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M. tuberculosis H37Rv Rv2686c (-)

annotation: PROBABLE ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE LEUCINE AND ALANINE AND VALINE RICH PROTEIN ABC TRANSPORTER
coordinates: 3003280 - 3004038
length: 252

RAISSLAGPRALAAFGRNDIRGTYRDPLLVMLVIAPVIWTTGVALLTPLFTEMLARRYGFDLVGYYPLIL
TAFLLLTSIIVAGALAAFLVLDDVDAGTMTALRVTPVPLSVFFGYRAATVMVVTTIYVVATMSCSGILEP
GLVSSLIPIGLVAGLSAVVTLLLILAVANNKIQGLAMVRALGMLIAGLPCLPWFISSNWNLAFGVLPPYW
AAKAFWVASDHGTWWPYLVGGAVYNLAIVWVLFRRFRAKHA*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv2686c - - 100% (252) PROBABLE ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE LEUCINE AND ALANINE AND VALINE RICH PROTEIN ABC TRANSPORTER

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2705c - 1e-142 100.00% (252) antibiotic ABC transporter transmembrane protein
M. gilvum PYR-GCK - - - - -
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_1860 - 1e-107 75.93% (241) antibiotic ABC transporter membrane protein
M. marinum M MMAR_2028 - 1e-111 81.15% (244) antibiotic-transport integral membrane leucine, alanine and
M. avium 104 - - - - -
M. smegmatis MC2 155 MSMEG_1504 - 1e-110 78.01% (241) antibiotic ABC transporter transmembrane protein
M. thermoresistible (build 8) - - - - -
M. ulcerans Agy99 - - - - -
M. vanbaalenii PYR-1 Mvan_0774 - 1e-98 69.71% (241) putative antibiotic-transport integral membrane leucine and

CLUSTAL 2.0.9 multiple sequence alignment


Rv2686c|M.tuberculosis_H37Rv        MRAISSLAGPRALAAFGRNDIRGTYRDPLLVMLVIAPVIWTTGVALLTPL
Mb2705c|M.bovis_AF2122/97           MRAISSLAGPRALAAFGRNDIRGTYRDPLLVMLVIAPVIWTTGVALLTPL
MMAR_2028|M.marinum_M               MSAPAG-ASIRALIAFGRNDIRGTYREPLLVMIVVAPAIWTSAVALLTPR
MAB_1860|M.abscessus_ATCC_1997      ------MMPIRVWAAFGRNDIRGTYRDPLLIMVVLAPIIWTTGVAVLTPQ
MSMEG_1504|M.smegmatis_MC2_155      MTEVLPAGTLRAVAAFGRKDIRGTYRDPLLIMLVVAPVIWTSLVAVLTPR
Mvan_0774|M.vanbaalenii_PYR-1       -MSVSMTPRLRAWAAFGRNDLRGTYRDPLLVMLVLAPAIWTIGTAVVVPR
                                              *.  ****:*:*****:***:*:*:** ***  .*::.* 

Rv2686c|M.tuberculosis_H37Rv        FTEMLARRYGFDLVGYYPLILTAFLLLTSIIVAGALAAFLVLDDVDAGTM
Mb2705c|M.bovis_AF2122/97           FTEMLARRYGFDLVGYYPLILTAFLLLTSIIVAGALAAFLVLDDVDAGTM
MMAR_2028|M.marinum_M               VTTMLADRNGFDLRPYYPLILTAFLLLTSIIIVGGLAAFLVLDEVDAGTL
MAB_1860|M.abscessus_ATCC_1997      ATDLLSATRGFDLVPYYPLVLTAFLLLTSIIIPGALAAFLVLDDVDAGTL
MSMEG_1504|M.smegmatis_MC2_155      FTETLGARYDFDLVPYYPLVLTGFLLLTSIIVAGGLGAFLVLDEVDAGTM
Mvan_0774|M.vanbaalenii_PYR-1       LSVALAQRYDFDLVPYYPLVVTGLLLLTSIIIVGGLAAFLVLDEIDAGTL
                                     :  *.   .***  ****::*.:*******: *.*.******::****:

Rv2686c|M.tuberculosis_H37Rv        TALRVTPVPLSVFFGYRAATVMVVTTIYVVATMSCSGILEPGLVSSLIPI
Mb2705c|M.bovis_AF2122/97           TALRVTPVPLSVFFGYRAATVMVVTTIYVVATMSCSGILEPGLVSSLIPI
MMAR_2028|M.marinum_M               AALRVTPVPLSTFFVYRAATVMVVTTIYVVATLSLSGILELRLLPSLIPI
MAB_1860|M.abscessus_ATCC_1997      TALRVTPVPMSGYFLYRAATVVVITTVYVVATLSLSGILEPGVLPALIPI
MSMEG_1504|M.smegmatis_MC2_155      TALRVTPVPIATFFAYRAVTVMLVTTVYVVATLPLSGILAPGLVGPLVPI
Mvan_0774|M.vanbaalenii_PYR-1       TALRVTPVTLASFFGYRAATVVAVTTAYVAVTIPLTGLLPSSVVWPLIPI
                                    :*******.:: :* ***.**: :** **..*:. :*:*   :: .*:**

Rv2686c|M.tuberculosis_H37Rv        GLVAGLSAVVTLLLILAVANNKIQGLAMVRALGMLIAGLPCLPWFISSNW
Mb2705c|M.bovis_AF2122/97           GLVAGLSAVVTLLLILAVANNKIQGLAMVRALGMLIAGLPCLPWFISSNW
MMAR_2028|M.marinum_M               GLLAGLSAVVTLLLILAVANNKIQGLAAVRALGMLIAGLPCLPWFIHSNW
MAB_1860|M.abscessus_ATCC_1997      GMLSGLSAVVTLLLVIAFANNKIQGLAAVRALGMLIAGLPCLPWFIHSNW
MSMEG_1504|M.smegmatis_MC2_155      GMLAGLSAVVTLLAVVALAGDKIQGIAMVRALGMLIAGLPCVPWFIDSAW
Mvan_0774|M.vanbaalenii_PYR-1       GMVAGLSSVVTMLLIVAVASNKVQGIAMLRLLGLLIAGIPCLPWFVDSAW
                                    *:::***:***:* ::*.*.:*:**:* :* **:****:**:***: * *

Rv2686c|M.tuberculosis_H37Rv        NLAFGVLPPYWAAKAFWVASDHGTWWPYLVGGAVYNLAIVWVLFRRFRAK
Mb2705c|M.bovis_AF2122/97           NLAFGVLPPYWAAKAFWVASDHGTWWPYLVGGAVYNLAIVWVLFRRFRAK
MMAR_2028|M.marinum_M               NFVFAVLPPYWPAKAFWLASDHATWWPYLVAGSAYNLALAWALFRRFHAK
MAB_1860|M.abscessus_ATCC_1997      GYAFGVLPPFWAAKAFWVASAHGMWWPFVLIGVAYNLLIAWALLRRFLAK
MSMEG_1504|M.smegmatis_MC2_155      NLAFGVLPPYWAAKAFWVASAHGTWWPYLVVGAVYNVVVAWPLFRRFQAR
Mvan_0774|M.vanbaalenii_PYR-1       NLAFGVLPPYWAAKAFWVACANGTWWPYLIGGVVFNAAAGWPLLRRFVAK
                                    . .*.****:*.*****:*. :. ***::: * .:*    * *:*** *:

Rv2686c|M.tuberculosis_H37Rv        HA---
Mb2705c|M.bovis_AF2122/97           HA---
MMAR_2028|M.marinum_M               HVASV
MAB_1860|M.abscessus_ATCC_1997      NL---
MSMEG_1504|M.smegmatis_MC2_155      HG---
Mvan_0774|M.vanbaalenii_PYR-1       NT---
                                    :

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv2686c	-	-	100% (252)	PROBABLE ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE LEUCINE AND ALANINE AND VALINE RICH PROTEIN ABC TRANSPORTER