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TQSTRDRAVDVIRLAALVVVMFGHCALLLATIDSGGVRIANLIGEVPAVAPATWVVQVMPLFFLAGGAAG VHSYHTGTPWGAWLFRRAQRLCRPVFWYLAVWAAVLAAARVVLGADSAVRLGGESVALLWFLGVYLVALA FVPALVRLRSGRAVAGVLAALLVVAASTDALRFATGDEAAGLTNFVIVWLIPVVIGVGYAQRLIGRRAAA VGAAAAFTTAWALVVFGPYEVSLVVTGAERISNVSPPTLLLAMHCVWMSCVFVVAAAAIGRWARRPRVWR VVAAGNAGAMTLYLWHIVAIAIAAFGLHAVGLQAYDVAAPDLWAQLLVRTLVFAVVMLILFRLLSPLERR PLPWWDGAVTESGPRAIGAGALVCAAGVALVLTAKFGLGESAGWAACAGFVAAVVAARFCARVAPHDLGP DVRSPSESPENENLEHIASNS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3453 | - | - | 100% (442) | hypothetical protein Mflv_3453 |
| M. gilvum PYR-GCK | Mflv_3017 | - | 5e-36 | 32.29% (353) | hypothetical protein Mflv_3017 |
| M. gilvum PYR-GCK | Mflv_1873 | - | 3e-06 | 25.62% (320) | hypothetical protein Mflv_1873 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1297c | - | 7e-88 | 43.20% (412) | hypothetical protein MAB_1297c |
| M. marinum M | MMAR_2582 | - | 1e-152 | 63.87% (429) | hypothetical protein MMAR_2582 |
| M. avium 104 | MAV_4113 | - | 2e-80 | 42.36% (432) | hypothetical protein MAV_4113 |
| M. smegmatis MC2 155 | MSMEG_3709 | - | 1e-158 | 64.62% (424) | hypothetical protein MSMEG_3709 |
| M. thermoresistible (build 8) | TH_0209 | - | 1e-55 | 46.36% (261) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3178 | - | 1e-146 | 62.24% (429) | hypothetical protein MUL_3178 |
| M. vanbaalenii PYR-1 | Mvan_3210 | - | 1e-170 | 69.39% (428) | hypothetical protein Mvan_3210 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3453|M.gilvum_PYR-GCK ----------------MTQSTRDRAVDVIRLAALVVVMFGHCALLLATID
Mvan_3210|M.vanbaalenii_PYR-1 ----------------MTHATRDRAVDVARLAALVVVMFGHCALLLATID
MMAR_2582|M.marinum_M -MRKTSLTPDPAALARSTPPGRDRAVDVARLCALVVVMFGHCALLLATID
MUL_3178|M.ulcerans_Agy99 -MRKTSLTPDPAALARSTPPGRVRAVDVARLWALVVVMFGHRALLLATID
TH_0209|M.thermoresistible__bu --------------------------------------------LPATID
MSMEG_3709|M.smegmatis_MC2_155 MPTPEAVPTRASDVDRATRPDRDRAVDVARLAALVAVMFGHCALLLATID
MAB_1297c|M.abscessus_ATCC_199 -MTMTLGLPTADEVGAATPATRDRALDVIRIVSLAGVVLGHTIMAVSTID
MAV_4113|M.avium_104 -----MRFPDAAEVAARTPADRDRVLDVIRIVSLGGVVLGHTVMAASIIR
: *
Mflv_3453|M.gilvum_PYR-GCK SGGVRIANLIGEVPAVAPATWVVQVMPLFFLAGGAAGVHSYHTG------
Mvan_3210|M.vanbaalenii_PYR-1 GSGVRIGNLIGQVPAVAPVTWIVQVMPLFFLAGGAAGAYGHRAG------
MMAR_2582|M.marinum_M SHGVRIGNLLGELPALTPLTWLVQVMPLFFLAGGAAGAYGWHPT---EPA
MUL_3178|M.ulcerans_Agy99 SHGVRIGNLLGELPALTPLTWLVQVMPLFFMAGGAAGAYGWHPT---EPA
TH_0209|M.thermoresistible__bu RGGVRIANILGALPALAPVTWAVQVMPLFFLAGGAAGAYGWCAANRRDQA
MSMEG_3709|M.smegmatis_MC2_155 STGVRVGNILGALPALAPITWILQVMPLFFLAGGAAGTYSRHAG------
MAB_1297c|M.abscessus_ATCC_199 NGVLLWGNLLNGRPVFQALTWVFQIMPLFFFAGVAASVGSWKPG------
MAV_4113|M.avium_104 DHVLIWDNLLTTSALFQAMTWLLQIMPLFFFAGAAACVSSWTPG------
: *:: . . . ** .*:*****:** ** . . .
Mflv_3453|M.gilvum_PYR-GCK TPWGAWLFRRAQRLCRPVFWYLAVWAAVLAAARVVLGADSAVRLGGESVA
Mvan_3210|M.vanbaalenii_PYR-1 TPWGAWLFTRAQRLYRPVFWYLAAWSVGLLAAWAALGADSAAGLGGESVA
MMAR_2582|M.marinum_M VPWGAWLLTRAQRLCRPVFWYLAAWTGALVVVRATLGAQSAAGLGRECVA
MUL_3178|M.ulcerans_Agy99 VPWGAWLLTRAQRLCRPVFWYLAAWTGALVVVRATLGAQSAAGLGRECVA
TH_0209|M.thermoresistible__bu PTWGGWLMVRAQRLCRPLFCYLGMWAVALLTLRLTVGGADADRIGREVVA
MSMEG_3709|M.smegmatis_MC2_155 TPWGTWLFTRAQRLCRPVFAYLAAWVVALVAVHLTLGADSTAALGRECVA
MAB_1297c|M.abscessus_ATCC_199 TSWGSWLMHRCTRLYRPVFYYLGFWAVALLILRQILPLHVYEPVAGVSTQ
MAV_4113|M.avium_104 TDWGGWLMRRCTRLFRPVFYYLAFWAVTLTVLYQALPQHIYEPIAGVSTQ
** **: *. ** **:* **. * * : :. .
Mflv_3453|M.gilvum_PYR-GCK LLWFLGVYLVALAFVPALVRLRSGRAVAGVLAALLVVAASTDALRFATGD
Mvan_3210|M.vanbaalenii_PYR-1 LLWFLGVYVVTLAFVPALVRMRTGRAAAVVIAFLVAAAAAMDAVRLNTGT
MMAR_2582|M.marinum_M LLWFLGVYLVVLAFVPALTRLRTGYGIAAVSVTLLVLAAAVDQIRFAVGT
MUL_3178|M.ulcerans_Agy99 LLWFLGVYLVVLAFVPALTRVRTGYGIATVSVTLLVLAAAVDQIRLAVGT
TH_0209|M.thermoresistible__bu LLWFLGVYLIVPALVPAMTRLRT---------------------------
MSMEG_3709|M.smegmatis_MC2_155 LLWFLGVYLVVLAFVPALTRMSSGRAVGALVTALVALAAVFDGLRFAVGT
MAB_1297c|M.abscessus_ATCC_199 LLWFLGAYVLVLAAIPLLARITTTRAMFTALAAVYLGIAAIDVLRLGLDA
MAV_4113|M.avium_104 LLWFLGAYVLVLAAMPVLYRITTTGRLAAGVAAVYGAIALIDVIRLHWPA
******.*::. * :* : *: :
Mflv_3453|M.gilvum_PYR-GCK EAAGLTNFVIVWLIPVVIGVGYAQRLIGRRAAAVGAAAAFTTAWALVVFG
Mvan_3210|M.vanbaalenii_PYR-1 PAVAVGNFLFVWLIPVALGVAYARRLIGRHVALAVAVAAFAVQTVLVAAG
MMAR_2582|M.marinum_M AESGAANFLIVWLIPVALGVGYARRLIGPRAALVAAVAAFAAQLRLAGTG
MUL_3178|M.ulcerans_Agy99 AESGAANFLIVWLIPVALGVGYARRLIGPRAALVAAVDAFAAQLRLVGTG
TH_0209|M.thermoresistible__bu -----------------------------AAAPMVLVVAFCGQLILAATG
MSMEG_3709|M.smegmatis_MC2_155 PAAGTANLVVVWLIPVVIGVAYARRLIRPRIALAVAVCTLAGQIMLALVG
MAB_1297c|M.abscessus_ATCC_199 PKGIGYVNFVVWLLPAVLGVGYRRQLITQRAALVLAATVFAINVALVTFG
MAV_4113|M.avium_104 LMPLGYLNLAVWLIPAMFGAAYRRGLLGGRAALAVAAAFFAADVALVRWG
* . : *. *
Mflv_3453|M.gilvum_PYR-GCK PYEVSLVVTGAERISNVSPPTLLLAMHCVWMSCVFVVAAAAIGRWARRPR
Mvan_3210|M.vanbaalenii_PYR-1 PYEVSLVVTGTEQISNVSPPTLLLAMHCLWMSCLFVAAAGAIGRWAQRPR
MMAR_2582|M.marinum_M VYDVSLVVTGADRMSNVAPPTLLLALHCTWMSCAFVAAAAVIRRWAARPR
MUL_3178|M.ulcerans_Agy99 VYDVSLVVTGADRMSNVAPPTLLLALHCTWMSCAFVAAAAVIRRWAGRPR
TH_0209|M.thermoresistible__bu RYEVALVVTGIERVSNVSPPTLVLALQCTWMSCAFVVAAPAVRRLAERP-
MSMEG_3709|M.smegmatis_MC2_155 PYDVSLVVTGAERVSNVSPPTMLLALHCTWVSCLFVACARAVGRWAHRPR
MAB_1297c|M.abscessus_ATCC_199 PYTISLVGVAGQKVPNMIPPSLVLAGHAIILSALASAAMPAINRWAQRPR
MAV_4113|M.avium_104 PYQLSMVGTGDHHLSNTSPPSLLLAGHAIILSALAIAAAPAIARWAQRPR
* :::* .. .::.* **:::** :. :*. .. .: * * **
Mflv_3453|M.gilvum_PYR-GCK VWRVVAAGNAGAMTLYLWHIVAIAIAAFGLHAVGLQAYDVAAPDLWAQLL
Mvan_3210|M.vanbaalenii_PYR-1 VWTVVAAGNAGAMTLYLWHIVAIAIAAFGLHALGVDAYDVTASGFWGLLA
MMAR_2582|M.marinum_M VWQLVAMGNGGAMTLYLWHIPAIAVAAFVLHAVGLDAFDVHTPWFWCLLA
MUL_3178|M.ulcerans_Agy99 VWQLVAMGNGGAMTLYLWHIPAIAVAAFVLHAVGLDAFDVHTPWFWCLLA
TH_0209|M.thermoresistible__bu --------------------------------------------------
MSMEG_3709|M.smegmatis_MC2_155 VWHVVAVGNGGAMTLYLWHIPVIAAAALGLHALGLDAFDPHAPEFWGLLA
MAB_1297c|M.abscessus_ATCC_199 VWWAVAIGNSGAMTLYLWHMPALLGMHLAFDFLGFDRYDTTAPDFIALSV
MAV_4113|M.avium_104 VWWWTAIGNSGAMTLYLWHMPVLLGVHLAFDYLGCPRFPG-APDFLAISV
Mflv_3453|M.gilvum_PYR-GCK VRTLVFAVVMLILFRLLSPLERRPLPWWDGA-VTESGPRAIGAGALVCAA
Mvan_3210|M.vanbaalenii_PYR-1 LRALVFSVVMFALFRLLAPLERHPLPWWDAP-ATAAGARATAAGALLCAS
MMAR_2582|M.marinum_M LRAVVFTLVMAATFWLLSPLEHRRLPWWDEP-VRVVGARASAAGLLVCGA
MUL_3178|M.ulcerans_Agy99 LRAVVFTLVMAATFWLLSPLEHRRLPWWDEP-VPVVGTRASASGLLVCGA
TH_0209|M.thermoresistible__bu ---------------------------WTG--------------------
MSMEG_3709|M.smegmatis_MC2_155 LRAVVFAVLMAIAFRLLSPIEHRPLPWWDDQ-VQATGARSIVAGALICVA
MAB_1297c|M.abscessus_ATCC_199 LQVATMMLLVTGLFLALRPLENNPLPGWDGGYIARPGARSAAAGTALMLA
MAV_4113|M.avium_104 AQVLLVVVAVAVLFVALRPLENNPLSGWDGAPAVMSRGWGAAVGALLCVA
*
Mflv_3453|M.gilvum_PYR-GCK GVALVLTAKFGLGESAGWAACAGFVAAVVAARFCARVAPHDLGPDVRSPS
Mvan_3210|M.vanbaalenii_PYR-1 AVVLVVMAKFGLGDGTGWSALAVFLGLAAAARTCAAAPAAVSGP--QAPT
MMAR_2582|M.marinum_M GVALLLVAKNGLSGAPGWVSLGCFLVALVAARAMTGPPSGAGEAERAPAA
MUL_3178|M.ulcerans_Agy99 RVALLLVAKNGLSGAPGWVSLGCFLVALVAARAMTGPPSGAGEAQRAPAA
TH_0209|M.thermoresistible__bu RAVLLVLAKSGLGGAVGWTALGVFLATAAAARITAGSPTRP--AATHPSA
MSMEG_3709|M.smegmatis_MC2_155 GAVLTLMAKNGLDGVVGWSALAGFVASTAAARLCAG-RTGP--AGTGSAA
MAB_1297c|M.abscessus_ATCC_199 GGFTLASVVWGLKGF-GLVCWVVVLAGLILARVLANRTKI----------
MAV_4113|M.avium_104 GVALLAAIRWGLKDD-GLVCMAVVVAALVAARIVAQHAGPAGHGSSSRPC
** * . .: ** :
Mflv_3453|M.gilvum_PYR-GCK ESPENENLEHIASNS
Mvan_3210|M.vanbaalenii_PYR-1 EVGSRRP--------
MMAR_2582|M.marinum_M VRQRVG---------
MUL_3178|M.ulcerans_Agy99 VRQRVG---------
TH_0209|M.thermoresistible__bu GDEAVGAIR------
MSMEG_3709|M.smegmatis_MC2_155 RG-------------
MAB_1297c|M.abscessus_ATCC_199 ---------------
MAV_4113|M.avium_104 SMA------------