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MVGNRRGVASRAALLEAGRTAFSAQRYDEVSIVDVARSLGVAAGSISYHFGGKRGFYLAVVEQAAEEFWS DLIQMRGPALERLADGIGKFLDRAQQEPRAFEALLADVADAEVRRIREQHRQRLAHALAVEITGTESTPI LRAAISGSLSFMEGIVLHWMHTDGVSRDAIRDLITANFIGTILSAVRSDPDIELSQRVVEAVLPDARLLS VFADPASLIPVTNNTQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2541c | - | - | 100% (227) | transcriptional regulatory protein TetR |
| M. abscessus ATCC 19977 | MAB_0483c | - | 1e-07 | 24.83% (149) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3650 | - | 2e-07 | 27.86% (140) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 5e-09 | 24.70% (166) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4581 | - | 7e-08 | 29.29% (140) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 1e-08 | 24.10% (166) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 1e-06 | 23.44% (209) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_1934 | - | 1e-07 | 34.55% (110) | hypothetical protein MMAR_1934 |
| M. avium 104 | MAV_4266 | - | 4e-07 | 27.39% (157) | hypothetical protein MAV_4266 |
| M. smegmatis MC2 155 | MSMEG_0735 | - | 5e-06 | 31.36% (118) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3297 | - | 2e-06 | 25.63% (199) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_2160 | - | 7e-08 | 33.64% (110) | hypothetical protein MUL_2160 |
| M. vanbaalenii PYR-1 | Mvan_3785 | - | 1e-07 | 31.71% (123) | hypothetical protein Mvan_3785 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1934|M.marinum_M ------------MTRAGVAG--------RRPNRRGNATRESMLEAALTSL
MUL_2160|M.ulcerans_Agy99 ------------MTRAGVAG--------RRPNRRGNATRESMIEAALTSL
Mvan_3785|M.vanbaalenii_PYR-1 ------------MTEAAAPA--------RRPNRRGQATRANMLEAALKSL
MSMEG_0735|M.smegmatis_MC2_155 ------------MTDAAQPGSGPRAERPNRPNRRGLATRENMLEAALQAL
Mb0310|M.bovis_AF2122/97 ---------------MGVPA--------KKKQQQGERSRESILDATERLM
Rv0302|M.tuberculosis_H37Rv ---------------MGVPA--------KKKQQQGERSRESILDATERLM
MLBr_00717|M.leprae_Br4923 ------------MTT-------------ARRRLSPEDRRAELLALGAEVF
MAV_4266|M.avium_104 ------------MAT-------------ARRRLSPEDRRAELLALGAEVF
Mflv_4581|M.gilvum_PYR-GCK MTFPQARSHGKTLPSEANSVATEKRAANASRSRASARRRETILDAALTVA
MAB_2541c|M.abscessus_ATCC_199 ---------------------------MMVGNRRGVASRAALLEAGRTAF
TH_3297|M.thermoresistible__bu ------------MDSDAAAP----------GVRKSDRTRLTILDAARVAF
* ::
MMAR_1934|M.marinum_M ASGDPGSVSANRIAKEIGATWGAVQYQFGDVDGFWAAVLHRTAERRAG--
MUL_2160|M.ulcerans_Agy99 ASGDPGSVSANRIAKAIGATWGAVQYQFGDADGFWAAVLHRTAERRAG--
Mvan_3785|M.vanbaalenii_PYR-1 ASGDPGSVSANRIAKDIGATWGAVQYQFGDADGFWAAVLHRTAERRA---
MSMEG_0735|M.smegmatis_MC2_155 ATGDPGAVSANRIAKQIGATWGAVKYQFGDIDGLWAAVLHRTAERRA---
Mb0310|M.bovis_AF2122/97 ATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA--
Rv0302|M.tuberculosis_H37Rv ATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA--
MLBr_00717|M.leprae_Br4923 GKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLY---
MAV_4266|M.avium_104 GKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLY---
Mflv_4581|M.gilvum_PYR-GCK AAGGYEAVQMRTVAERVGIAVGTLYRYFPAKTHLLVAALTREFRRLD---
MAB_2541c|M.abscessus_ATCC_199 SAQRYDEVSIVDVARSLGVAAGSISYHFGGKRGFYLAVVEQAAEEFWSDL
TH_3297|M.thermoresistible__bu ARKGFSGVTIRDITDLAGVTRANFYYYFKDKTELFVELGTATYREVLEVI
. . : * : . . * . .
MMAR_1934|M.marinum_M -----------------SMLALSKPLQSGRPLQERVAAVIETLFHGLASA
MUL_2160|M.ulcerans_Agy99 -----------------SMLALSKPLQSGRPLQERVAAVIETLFHGLASA
Mvan_3785|M.vanbaalenii_PYR-1 -----------------DVFASVDPDAS---LRDRVASIIDTLYDGLAEP
MSMEG_0735|M.smegmatis_MC2_155 -----------------GVLGRHDPGAP---LRQRVAGIIDMLYDGLTAS
Mb0310|M.bovis_AF2122/97 -----------------AIPTWDEAHGPVEQRSERQLTELVSLQS-QHPD
Rv0302|M.tuberculosis_H37Rv -----------------AIPTWDEAHGPVEQRSERQLTELVSLQS-QHPD
MLBr_00717|M.leprae_Br4923 -----------------AATNIPPPAGLTMFEEVRVGVLAYMAYHKQNPE
MAV_4266|M.avium_104 -----------------ENTNMDDVTGLTMYEEIRVGVLAYMAYHEQNPE
Mflv_4581|M.gilvum_PYR-GCK -----------------SAGDWASGEGPPLERLERLTAHLHDRWQ-----
MAB_2541c|M.abscessus_ATCC_199 IQM-----------RGPALERLADGIGKFLDRAQQEPRAFEALLADVADA
TH_3297|M.thermoresistible__bu ETFSDTASPVIIDQWVSRYFTYLDRNGAFVIRSEEDMPQDGAFRTAVARS
.
MMAR_1934|M.marinum_M DSRAIENLRAALPRDPGELERLYPRTA-----------------AELFSW
MUL_2160|M.ulcerans_Agy99 DSRAIENLRAALPRDPGELERLYPRTA-----------------AELFSW
Mvan_3785|M.vanbaalenii_PYR-1 DSRAIENLRAALPRDPAELERLYPQTA-----------------AELFSW
MSMEG_0735|M.smegmatis_MC2_155 DSRAIENLRAALPRDRAELERLYPRTA-----------------AELSSW
Mb0310|M.bovis_AF2122/97 FLRLFYLLSMERSQDPVVAAVVRRVRN-----------------TAIARF
Rv0302|M.tuberculosis_H37Rv FLRLFYLLSMERSQDPAVAAVVRRVRN-----------------TAIARF
MLBr_00717|M.leprae_Br4923 ---AAWAAYVGLGRSDPVLLGIDDEAK-----------------NRQMEH
MAV_4266|M.avium_104 ---AAWAAYVGLGRSDPVLLGVEDDAK-----------------NRQMEH
Mflv_4581|M.gilvum_PYR-GCK ---RDPRLTTAMTR---AFAVADTRAA-----------------AELDRA
MAB_2541c|M.abscessus_ATCC_199 EVRRIREQHRQRLAHALAVEITGTEST-----------------PILRAA
TH_3297|M.thermoresistible__bu HRRAAQALGQQIAKASSTPLAADEAATGLVVMAMLERSWLIHHNGVFDAP
MMAR_1934|M.marinum_M GRSWLETCQNAFADLDVDPNRVREVA--ALIPGAMRG--LVSERQLG-SY
MUL_2160|M.ulcerans_Agy99 GRSWLETCQNAFANLDVDPNRVREVA--ALIPGAMRG--LVSERQLG-SY
Mvan_3785|M.vanbaalenii_PYR-1 GQSWLQICHNAFAGLGVDPDRVREVA--TLIPGAMRG--LVSERQLG-SY
MSMEG_0735|M.smegmatis_MC2_155 GQGWLATCQQAFADLDVDPERVREVA--SFIPGAMRG--ITSERQLG-TY
Mb0310|M.bovis_AF2122/97 RDSITHLLPSDIPPGKAD-LVVAELT--AFAVALSDG--VYFAGHLEPDT
Rv0302|M.tuberculosis_H37Rv RDSITHLLPSDIPPGKAD-LVVAELT--AFAVALSDG--VYFAGHLEPDT
MLBr_00717|M.leprae_Br4923 IMSRIGDVVSVVPESKLHPDIERDLR--VIVHGWLAFTFEVCRQRIMDPS
MAV_4266|M.avium_104 IMSRINQLLAEVP-ATLEPDVERHLR--VILHGWLAFTFEICRQRIIDPT
Mflv_4581|M.gilvum_PYR-GCK ADEIQILLARTLRGGEPTPTDLHVAG--VISDIWLAN-LVAFSGHRATAA
MAB_2541c|M.abscessus_ATCC_199 ISGSLSFMEGIVLHWMHTDGVSRDAIRDLITANFIGTILSAVRSDPDIEL
TH_3297|M.thermoresistible__bu RDVVLAAASEVIRRLVEDDGRPGTSIQEILPRVSVEPQRCRDGTQLEPGR
. :
MMAR_1934|M.marinum_M ADLELARRALTNALAGYLKNSRTP----------------
MUL_2160|M.ulcerans_Agy99 ADLELARRALTNALAGYLKNSRTP----------------
Mvan_3785|M.vanbaalenii_PYR-1 ADLDVARRGLTNALVAYLQAAD------------------
MSMEG_0735|M.smegmatis_MC2_155 TDLDVARRGLTNAIVSYLEDNGSGRRE-------------
Mb0310|M.bovis_AF2122/97 TDVERMYRRLRQALEALIPVLLEET---------------
Rv0302|M.tuberculosis_H37Rv TDVERMYRRLRQALEALIPVLLEET---------------
MLBr_00717|M.leprae_Br4923 TDADRLADSCAHALLDAIARVPEISKELADAMAIARQPPQ
MAV_4266|M.avium_104 TDADKLADACAHALLDAIGRVPEIPEELGEAMANSRL---
Mflv_4581|M.gilvum_PYR-GCK DTRERIDRATRRVVTSAARPTANR----------------
MAB_2541c|M.abscessus_ATCC_199 SQRVVEAVLPDARLLSVFADPASLIPVTNNTQ--------
TH_3297|M.thermoresistible__bu APAQQALASHRHASGSTWPHRPEVIRATGRTQT-------