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PPTTPTPPPAPTPIPQLPANDFHQYSHGVSALGGWFPIAVQVLAVVVLLVVIGWRSRRWRLLWVPVSVAF GALGALAAWMYMNSEGLASDPAPFRLWLWIGVFATSVAVAAVGFRSARWWRRGVSLLAIPLTLLAALVAL NTWVGYYPTVQAAWGAISAGPLPNEVDMSDLAGLRNSTPATGKLVPVDIPADASGFKHRGEYVYLPPAWF AGETPPRLPVVMMIAGEFNTPADWVRTGNATKMIDDYAASHAGQAPIFVFVDVAGSFNNDTECVNGPRGN AASHLTEDVRPYVVSEFDSSPDPANWAVVGWSMGGTCAVDLTVMHPDLFSTFVDIAGDHGPTAGTKQQTI DRLYGGDAAQWDAFDPRTVMAKHGPYTGVTGWFEDAIPPADAKKPSGPKRPTADTPTGIGGHDDVTDDDR EGAAQDLCAAAQRVQISCSIHQMISGHTWQFASRTFSDALPWLAAQIRTPGATG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2451c | - | - | 100% (475) | hypothetical protein MAB_2451c |
| M. abscessus ATCC 19977 | MAB_2318c | - | e-134 | 51.33% (450) | hypothetical protein MAB_2318c |
| M. abscessus ATCC 19977 | MAB_1022 | - | e-116 | 45.83% (456) | hypothetical protein MAB_1022 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1666c | - | 1e-145 | 52.40% (479) | hypothetical protein Mb1666c |
| M. gilvum PYR-GCK | Mflv_3545 | - | 1e-139 | 51.56% (450) | putative esterase |
| M. tuberculosis H37Rv | Rv1639c | - | 1e-145 | 52.40% (479) | hypothetical protein Rv1639c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2446 | - | 1e-140 | 52.80% (447) | hypothetical protein MMAR_2446 |
| M. avium 104 | MAV_3129 | - | 1e-140 | 53.83% (444) | putative esterase family protein |
| M. smegmatis MC2 155 | MSMEG_3797 | - | 1e-139 | 52.01% (448) | putative esterase family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1625 | - | 1e-139 | 52.80% (447) | hypothetical protein MUL_1625 |
| M. vanbaalenii PYR-1 | Mvan_3331 | - | 1e-139 | 52.49% (442) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1666c|M.bovis_AF2122/97 ------MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLV
Rv1639c|M.tuberculosis_H37Rv ------MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLV
MMAR_2446|M.marinum_M ------------MTTS-PPALARVLASTHTSLMHGWVPVTVQVVTAIVLL
MUL_1625|M.ulcerans_Agy99 ------MFDNETVTTS-PPALARVLASTHTSLMHGWVPDTVQVVTAIVLL
MAV_3129|M.avium_104 ------------------------------------MPMTVQVLAGVVLT
Mflv_3545|M.gilvum_PYR-GCK -------------------MTLPYLARHDLSLMHGWVPVSVQILAAAAMI
Mvan_3331|M.vanbaalenii_PYR-1 --------------------------------MHGWLPVAVQILAVVAVV
MSMEG_3797|M.smegmatis_MC2_155 -----------------------MTFTHHLSLMHGWVPTTVQVVTAVILI
MAB_2451c|M.abscessus_ATCC_199 MPPTTPTPPPAPTPIPQLPANDFHQYSHGVSALGGWFPIAVQVLAVVVLL
.* :**::: :
Mb1666c|M.bovis_AF2122/97 LAAGWRSRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLW
Rv1639c|M.tuberculosis_H37Rv LAAGWRSRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLW
MMAR_2446|M.marinum_M LAIGWRS----RRRLPAAVIFGAIAAWATRWYLG--TLANE--PVPAALW
MUL_1625|M.ulcerans_Agy99 LAIGWRS----RRRLPAAVIFGAIAAWVTRWYLG--TLANE--PVPAALW
MAV_3129|M.avium_104 LAVGWRSRRWRTVWVPVAALAGAAVAYLTHWYIVDRGLSDE--PAPAALW
Mflv_3545|M.gilvum_PYR-GCK AAVGWRTRRWRRVWVPWAASIGGGLAFTTYCYIRSAGVADESNPAPPTLW
Mvan_3331|M.vanbaalenii_PYR-1 TAIGRRTRRWRLVWVPWSALIGVVLAVAAYCYIASAGVADDSNPAPHTLW
MSMEG_3797|M.smegmatis_MC2_155 AAVGRRTWRWHLIWLPAAAAVGAVLALGTFWYIQSEGLAG--NPAPRSLW
MAB_2451c|M.abscessus_ATCC_199 VVIGWRSRRWRLLWVPVSVAFGALGALAAWMYMNSEGLASD--PAPFRLW
. * *: :* :. * * : *: ::. * **
Mb1666c|M.bovis_AF2122/97 IWVALTGAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYF
Rv1639c|M.tuberculosis_H37Rv IWVALTGAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYF
MMAR_2446|M.marinum_M VWVGLTAVAAAMLVVGWRGARWRRRTASLVAVPFCALCAALGLNIWVGYF
MUL_1625|M.ulcerans_Agy99 VWVGLTAVAAAMLVVGWRGARWRRRTASLVAVPLCALCAALGLNIWVGYF
MAV_3129|M.avium_104 LWVMLTGTAVAVLVLGWRTARRWRRGAAVLAVPLCLLSAALVLNLWVGYF
Mflv_3545|M.gilvum_PYR-GCK VWIALSGTAFGVLVAGWRGARRWRRTASALAVPLCALAAALVLNLWVGYF
Mvan_3331|M.vanbaalenii_PYR-1 VWIALSGFAFGVLVSGWRGARWWRRTAATLAVPLCVLSAALVVNLWVGYF
MSMEG_3797|M.smegmatis_MC2_155 VWIAISGATVVVLVAGWPRSRWWRRGASALAIPMSVLCAALALNLWVGYF
MAB_2451c|M.abscessus_ATCC_199 LWIGVFATSVAVAAVGFRSARWWRRGVSLLAIPLTLLAALVALNTWVGYY
:*: : . : : *: :* ** .: :*:*: *.* : :* ****:
Mb1666c|M.bovis_AF2122/97 PTVQTAWNQLTSGPLPDQADQAAVAALAHSGVRPSHGTLLPVVIPSDASH
Rv1639c|M.tuberculosis_H37Rv PTVQTAWNQLTSGPLPDQADQAAVAALAHSGVRPSHGTLLPVVIPSDASH
MMAR_2446|M.marinum_M PTVQAAWNQLSSGPLPDQADPAAVVAMAGKGVRPAHGSMVPVAIPSNASH
MUL_1625|M.ulcerans_Agy99 PTVQAAWNQLSSGPLPDQADPAAVVAMAGKGVRPAHGSMVPVAIPSNASH
MAV_3129|M.avium_104 PTVQSAWSQLTSGPLPDQTDQATVTAMAASRIRPPHGTVVPVAIPSDGSH
Mflv_3545|M.gilvum_PYR-GCK PTVDTAWNQLTAGPVPDQTDQVVVAALQKQHAVPIKGSVVPVQIPSTASG
Mvan_3331|M.vanbaalenii_PYR-1 PTVQTAWNQLTAGPLPDQTDAVTVAAMQKQHAMPVKGSLVAVDIPDTASG
MSMEG_3797|M.smegmatis_MC2_155 PWVQTAWNQLTAGPLPDQTDQVTVAAMQRDGAVPAKGTVVPVQIPNTASG
MAB_2451c|M.abscessus_ATCC_199 PTVQAAWGAISAGPLPNEVDMSDLAGLRNS--TPATGKLVPVDIPADASG
* *::**. :::**:*::.* :..: . * *.::.* ** .*
Mb1666c|M.bovis_AF2122/97 FKHRGELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGN
Rv1639c|M.tuberculosis_H37Rv FKHRGELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGN
MMAR_2446|M.marinum_M FKHRGELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGN
MUL_1625|M.ulcerans_Agy99 FKHRGELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGN
MAV_3129|M.avium_104 FKHRGELVYLPPEWFA------TTPPPALPTVMMIGGQFNTPADWTRAGN
Mflv_3545|M.gilvum_PYR-GCK FTHRQEFVYVPPAWFA------SDPPPALPVVMMIGGEFNTPADWLRAGE
Mvan_3331|M.vanbaalenii_PYR-1 FRHRQEWVYLPPAWYA------SDPPPALPTVMMIGGEFNTPADWLRAGG
MSMEG_3797|M.smegmatis_MC2_155 FRHRQEYVYLPPAWFA------ANPPPKLPTVMMIGGEFNTPADWMRAGN
MAB_2451c|M.abscessus_ATCC_199 FKHRGEYVYLPPAWFA------GETPPRLPVVMMIAGEFNTPADWVRTGN
* ** * **:** *: .** **.****.*:******* *:*
Mb1666c|M.bovis_AF2122/97 AVKTLDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDV
Rv1639c|M.tuberculosis_H37Rv AVKTLDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDV
MMAR_2446|M.marinum_M AVRTIDDFALAHNGNAPVLVFVDSGGAFNNDTECVNGRRGNAADHLTKDV
MUL_1625|M.ulcerans_Agy99 AVRTIDDFALAHNGNAPVLVFVDSGGAFNNDTERVNGRRGNAADHLTKDV
MAV_3129|M.avium_104 AVKTIDDFAAAHHGQAPVLVFVDSGGAFNNDTECVNGVRGNAADHLTKDV
Mflv_3545|M.gilvum_PYR-GCK AVKILDEFARAHRGYAPVAVFVDPGGTFDNDTECVNGPRGNAADHLVKDV
Mvan_3331|M.vanbaalenii_PYR-1 AARTLDAFAAAHGGYAPVVVFVDPGGTFNNDTECVNGTRGNSADHLVKDV
MSMEG_3797|M.smegmatis_MC2_155 VISTVDAFAASHHGFAPVLVFVDPGGAFNNDTECVNGSRGNAADHLTKDV
MAB_2451c|M.abscessus_ATCC_199 ATKMIDDYAASHAGQAPIFVFVDVAGSFNNDTECVNGPRGNAASHLTEDV
. :* :* :* * **: **** .*:*:**** *** ***:*.**.:**
Mb1666c|M.bovis_AF2122/97 VPYMVSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDF
Rv1639c|M.tuberculosis_H37Rv VPYMVSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDF
MMAR_2446|M.marinum_M VPYMISAFGVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDF
MUL_1625|M.ulcerans_Agy99 VPYMISAFDVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDF
MAV_3129|M.avium_104 VPFMISAFGVSPHRSNWGVAGWSMGGTCAVDLTVMHPELFSAFVDVAGDF
Mflv_3545|M.gilvum_PYR-GCK VPYLKSQYGVSPAAAGWGVVGWSMGGTCAVDLTVMHPDIFSTFVDIAGDA
Mvan_3331|M.vanbaalenii_PYR-1 VPYMKSHFGVSSAAANWGVVGWSMGGTCAVDLTVMHPEVFSAFVDIAGDA
MSMEG_3797|M.smegmatis_MC2_155 VPYLEAHYGVSAAAAHWGIVGWSMGGTCAVDLAVMHPDMFSAFVDIAGDL
MAB_2451c|M.abscessus_ATCC_199 RPYVVSEFDSSPDPANWAVVGWSMGGTCAVDLTVMHPDLFSTFVDIAGDH
*:: : :. *. : *.:.************:**** :**:***:***
Mb1666c|M.bovis_AF2122/97 YPNAGNKTQTIVRLFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-
Rv1639c|M.tuberculosis_H37Rv YPNAGNKTQTIVRLFGGNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-
MMAR_2446|M.marinum_M YPNAGNKAETITRLFGGNADAWAAFDPTTVINRHGQYTGISGWFSISVPA
MUL_1625|M.ulcerans_Agy99 YPNAGNKAETITRLFGGNADAWAAFDPTTVINRHGQYTGISGWFSISVPA
MAV_3129|M.avium_104 FPNAGNKAQTIARLFGGNADAWAAFDPTTVINRHGPYRDVAGWFAISSD-
Mflv_3545|M.gilvum_PYR-GCK APNAGTRNETVQRLFGGDSAAYAAFDPTAVMERHGPYRGVEGWFAVN---
Mvan_3331|M.vanbaalenii_PYR-1 APNAGTQAETVDRLFGGDTAAYTSFDPTAVMTRHGPYRGVAGWFDVNGA-
MSMEG_3797|M.smegmatis_MC2_155 TPNSGTKAQTIDRLFGGNAAAWDAFDPTTVINRHGHYQDVAGWFDVN---
MAB_2451c|M.abscessus_ATCC_199 GPTAGTKQQTIDRLYGGDAAQWDAFDPRTVMAKHGPYTGVTGWFEDAIPP
*.:*.: :*: **:**: : :*** :*: :** * .: ***
Mb1666c|M.bovis_AF2122/97 GPPSP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCA
Rv1639c|M.tuberculosis_H37Rv GPPSP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCA
MMAR_2446|M.marinum_M GPGAPR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCA
MUL_1625|M.ulcerans_Agy99 GPGAPR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCA
MAV_3129|M.avium_104 GPPAPRRDIQLSDSGAIRLAAREAAANPGNQTAAAYSLCALGRANGIDCA
Mflv_3545|M.gilvum_PYR-GCK --------------------AVPGAATPNEQAVSAASLCGVGSRSGIACA
Mvan_3331|M.vanbaalenii_PYR-1 -------------------VAVSATAQPNDQAVAASSLCATGGRSGIDCA
MSMEG_3797|M.smegmatis_MC2_155 --------------------TGGPGTAPNDQAKAANSLCTLCSSHGIACA
MAB_2451c|M.abscessus_ATCC_199 ADAKKPSGPKRPTADTPTGIGGHDDVTDDDREGAAQDLCAAAQRVQISCS
. .:: :* ** * *:
Mb1666c|M.bovis_AF2122/97 VVPQPGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQ
Rv1639c|M.tuberculosis_H37Rv VVPQPGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQ
MMAR_2446|M.marinum_M VVPQPGRHDWPFADQVFARALPWLAGQVGTPGVPRIPLPGTAS---PATQ
MUL_1625|M.ulcerans_Agy99 VVPQPGRHDWPFADQVFARALPWLAGQLGTPGVPRIPLPGTAS---PATQ
MAV_3129|M.avium_104 VVPQPGRHDWPFADRAFAAALPWLAGALGTPGIPRTPLPATSSPAVGAPL
Mflv_3545|M.gilvum_PYR-GCK VVSRPGNHDWPFASTAFATALPWLAARIGTPGVPQTGFPGTVH---G---
Mvan_3331|M.vanbaalenii_PYR-1 VVSQPGNHDWPFASTAFTSALPWLAGRIGTPGVPQIDLPRTVS---G---
MSMEG_3797|M.smegmatis_MC2_155 VQAQPGTHDWPFATQAFKASLPWLAGAIGTPDVPVVGLPASAP---SAPA
MAB_2451c|M.abscessus_ATCC_199 IHQMISGHTWQFASRTFSDALPWLAAQIRTPGATG---------------
: . * * ** .* :*****. : **. .
Mb1666c|M.bovis_AF2122/97 IAGTGR------
Rv1639c|M.tuberculosis_H37Rv IAGTGR------
MMAR_2446|M.marinum_M VVPAGR------
MUL_1625|M.ulcerans_Agy99 EVPAGR------
MAV_3129|M.avium_104 VVPAERSNTGKR
Mflv_3545|M.gilvum_PYR-GCK ------------
Mvan_3331|M.vanbaalenii_PYR-1 ------------
MSMEG_3797|M.smegmatis_MC2_155 FIETGKTAGPK-
MAB_2451c|M.abscessus_ATCC_199 ------------