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MGVAAHQQIYRPVSGHGGAMSLGLEKHRRSVDIERGRISYLDIGAGSPTVFVHGVLTNSLLWRDVVTAVA ATGRRCIALDLPGHGHSPVPADGIDVTLSGLAQLIAEFLDSIGIDEFDLVANDTGGAVAQIMVARQPDRI RTLALTNCDTEGHVPPKLFKPVVALARPPLMALIGPRLFARRKVLRALLGAGYRKPGRLPDSIVESYGQP VFGTAESSRFLSKMLRAMHTRDLEAARAGLVTFTKPTLIAWGLGDYFFPLKYGQRLAELFGGPVTFETVP DGRLYFPDEDADRLLPLLYRHWHSAGRQESSTEVGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2289 | - | - | 100% (316) | putative hydrolase, alpha/beta hydrolase fold |
| M. abscessus ATCC 19977 | MAB_0195c | - | 4e-26 | 31.42% (261) | putative hydrolase, alpha/beta hydrolase fold |
| M. abscessus ATCC 19977 | MAB_4522c | - | 1e-11 | 26.76% (213) | epoxide hydrolase EphF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0079c | - | 5e-34 | 33.70% (270) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3236 | - | 2e-23 | 29.55% (291) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0077c | - | 6e-34 | 33.70% (270) | oxidoreductase |
| M. leprae Br4923 | MLBr_00685 | - | 5e-05 | 27.27% (88) | putative hydrolase |
| M. marinum M | MMAR_0223 | - | 1e-33 | 32.85% (277) | oxidoreductase |
| M. avium 104 | MAV_5254 | - | 8e-34 | 33.09% (272) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_6763 | - | 3e-26 | 32.64% (242) | oxidoreductase |
| M. thermoresistible (build 8) | TH_3479 | - | 4e-30 | 34.65% (254) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_4891 | - | 6e-33 | 32.49% (277) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5859 | - | 8e-29 | 32.13% (277) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3236|M.gilvum_PYR-GCK ---------------------------MSTVGVPSGTIAY------EDTG
Mvan_5859|M.vanbaalenii_PYR-1 ---------------------------MFTADVPAGPIAY------DDTG
MSMEG_6763|M.smegmatis_MC2_155 ---------------------------MPVIELPSGPIAY------EDTG
Mb0079c|M.bovis_AF2122/97 ---------------------------MSTIDISAGTIHY------EATG
Rv0077c|M.tuberculosis_H37Rv ---------------------------MSTIDISAGTIHY------EATG
MMAR_0223|M.marinum_M ---------------------------MPTIDINAGTIHY------EVTG
MUL_4891|M.ulcerans_Agy99 ---------------------------MPTIDINAGTIHY------EITG
MAV_5254|M.avium_104 ---------------------------MSTIDISAGTIHY------EATG
MAB_2289|M.abscessus_ATCC_1997 MGVAAHQQIYRPVSGHGGAMSLGLEKHRRSVDIERGRISY------LDIG
TH_3479|M.thermoresistible__bu -------------------------MSATTITVDDAAIEY------TDVG
MLBr_00685|M.leprae_Br4923 ------------------MPACQHQRHRPVVACGTRGTTFRVGSMRQPIH
:
Mflv_3236|M.gilvum_PYR-GCK -GDGPVMVFGHGLLMDGRQWRKVLPQLP--EYRCITPTLPMGAHTSPMRH
Mvan_5859|M.vanbaalenii_PYR-1 -GDGPVLVFGHGLLMDGRQWRKVIPRLP--GYRCITPTLPLGAHTVPMRD
MSMEG_6763|M.smegmatis_MC2_155 -GDGPVLVFGHGLLMDGRQWRKVIPLLP--GCRCITPTLPMGAHTAPMRP
Mb0079c|M.bovis_AF2122/97 PETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPLRP
Rv0077c|M.tuberculosis_H37Rv PETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPLRP
MMAR_0223|M.marinum_M PEHGRPVMFVHGYLMGGQLWRQVSERLAKRGLRCFAPTWPLGAHPRALGP
MUL_4891|M.ulcerans_Agy99 PEHGRPVMFVHGYLMGGQLWRQVSERLAEWGLRCFAPTWPLGTHPRALGP
MAV_5254|M.avium_104 PADGRPVVFVHGYLMGGQLWRQVGDRLAGRGLRCIAPTWPMGAHPEPLRR
MAB_2289|M.abscessus_ATCC_1997 --AGSPTVFVHGVLTNSLLWRDVVTAVAATGRRCIALDLPGHGHSPVPAD
TH_3479|M.thermoresistible__bu --GGPPIVFVHGAYVTGALWDDVVTRLS-RGHRCIAPTWPFGAQRTPVGD
MLBr_00685|M.leprae_Br4923 LGSGEPVLLLHPFMMSQTVWEIVAPQLANTERYEVFAPTMAAHHGGPSAS
* :: * * * :. . :
Mflv_3236|M.gilvum_PYR-GCK DADLTETGMANILADFLDALDLDDVTLVLNDWGG----GQFMISEGRDKR
Mvan_5859|M.vanbaalenii_PYR-1 DADLTQTGVAGILADFLDALDLDDVTLVLNDWGG----GQFVISEGRDKR
MSMEG_6763|M.smegmatis_MC2_155 DADLTEQGVAGILADFLDALDLKDVTLVLNDWGG----GQFLITDGRDAR
Mb0079c|M.bovis_AF2122/97 GADQTIGGVAGIVADVLAALELKDVVLVGNDTGG---VVTQLVAVHYPER
Rv0077c|M.tuberculosis_H37Rv GADQTIGGVAGIVADVLAALELKDVVLVGNDTGG---VVTQLVAVHYPER
MMAR_0223|M.marinum_M DADRSITGVGDLVADVLATLDLHDVVLVGNDTGG---VVAQLVAVRHPER
MUL_4891|M.ulcerans_Agy99 DADRSITGVGDLVADVLATLDLHDVVLVGNDTGG---VVAQLVAVHHPER
MAV_5254|M.avium_104 GADRTITGVAAMVAELLSALDLEDVVLVGNDTGG---VVSQLVAVHHRER
MAB_2289|M.abscessus_ATCC_1997 GIDVTLSGLAQLIAEFLDSIGIDEFDLVANDTGG---AVAQIMVARQPDR
TH_3479|M.thermoresistible__bu SVDLDVVACGRRIIGLLEQLDLRDVTLVANDSGGGITLSALGILGLDWSR
MLBr_00685|M.leprae_Br4923 SWMMSVSTLADHVEQQLDELGWDTAHLVGNSLGG----WVVFELERRGRA
. . : * : ** *. **
Mflv_3236|M.gilvum_PYR-GCK IGRMVLASVTAFDNYPPEPARPAALLCRMPGGGWVLSRMLGTRFFRHSRR
Mvan_5859|M.vanbaalenii_PYR-1 IGRLVLVSCEAFDNFPPKPARPAALLCRFPGGGWVLSRMLGTRLFRHSRR
MSMEG_6763|M.smegmatis_MC2_155 IGRLVLASCTAFDNYPPAPARPAAALCRLPGGGRLLTKMFGTRFFRHSRL
Mb0079c|M.bovis_AF2122/97 LGALVLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAY
Rv0077c|M.tuberculosis_H37Rv LGALVLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAARNRAY
MMAR_0223|M.marinum_M LGALVLTSCDAFEHFPPPILKPVILAAKSKKMFRAAIQTMRSPAARRRAY
MUL_4891|M.ulcerans_Agy99 LGALVLTSCDAFEHFPPPILKPVILAAKSKKMFRAAIQTMRSPAARRRTY
MAV_5254|M.avium_104 LGALVLTSCDAFEHFPPPVLRPVILAAKSKATFRAVAQAMRAPAVRKRAF
MAB_2289|M.abscessus_ATCC_1997 IRTLALTNCDTEGHVPPKLFKPVVALARPPLMALIGPRLFARRKVLRALL
TH_3479|M.thermoresistible__bu VSRLVFTNCDTFEHFPPKQFAPLVKLCRVAPPLGGAVLRLLATGPGLAFF
MLBr_00685|M.leprae_Br4923 RSVTGIAPAGGWTRWSLAKFEVIAKFVAGMPLVAVARGLGSRALSLPFSH
:. . .
Mflv_3236|M.gilvum_PYR-GCK AYGAMAKSGLPDELFDAWFAPAVENPAIRRDLVKFATGAPPRARLLEMSE
Mvan_5859|M.vanbaalenii_PYR-1 AYGALAKSGIPDAMFDEWFRPAVESAAIRRDLVKFATGSPSRRRLLELSE
MSMEG_6763|M.smegmatis_MC2_155 AYGALSKAGLPDGLFDEWFRPAVENAAVRRDLVKFATGAPPRRRLLELSE
Mb0079c|M.bovis_AF2122/97 AG---LSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRT-EVTTAVAA
Rv0077c|M.tuberculosis_H37Rv AG---LSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRT-EVTTAVAA
MMAR_0223|M.marinum_M GD---LAHADIDELAQRWVQPALSNPAIAEDLRQLTLSLHT-DVTRGVAA
MUL_4891|M.ulcerans_Agy99 GD---LAHADIDELAQRWVQPALSNPAIAEDLRQLTLSLHT-DVTRGVAA
MAV_5254|M.avium_104 DG---LAHSNIDALTELWVRPALSLPAVAEDLRRFTLSLRT-EVTTAAAA
MAB_2289|M.abscessus_ATCC_1997 GAGYRKPGRLPDSIVESYGQPVFGTAESSRFLSKMLRAMHT-RDLEAARA
TH_3479|M.thermoresistible__bu KR-AVTRNGITGDRDDAIFGGFLSSAAVRREAVRFSAGLHP-QHTAAAAQ
MLBr_00685|M.leprae_Br4923 RLASLPLTGSPAGLSEHQLRNIVEDAG--HCPAYFLLLIKT--LLQPGLR
. . . : .
Mflv_3236|M.gilvum_PYR-GCK QMRTFDRPVLVIWAREDRMMPL-EHADRLVELYPD-ATKIVVDDSWTLIP
Mvan_5859|M.vanbaalenii_PYR-1 NLATFDRPVLVVWAREDRMMPL-QHADRLVELFSD-ARKVVVDDSWTLIP
MSMEG_6763|M.smegmatis_MC2_155 RLRTFTRPVLVVWAREDRMMPL-DHADRLVELFPD-ATKVIVDDSWTLIP
Mb0079c|M.bovis_AF2122/97 RLPEFDKPALIAWSADDVFFAL-ENGQRLAATIPR-ARFEVIEGARTFSM
Rv0077c|M.tuberculosis_H37Rv RLPEFDKPALIAWSADDVFFAL-ENGQRLAATIPR-ARFEVIEGARTFSM
MMAR_0223|M.marinum_M RLPEFSKPALIAWSADDKFFAL-EDGRRLAATIPN-ARLELIEGARTFSM
MUL_4891|M.ulcerans_Agy99 RLPEFSKPALIAWSADDKFFAL-EDGRRLAATIPN-ARLELIEGARTFSM
MAV_5254|M.avium_104 RLYDFDKPTLIAWSADDVFFAQ-EDGARLAATIPN-ARHEVIAGARTFSM
MAB_2289|M.abscessus_ATCC_1997 GLVTFTKPTLIAWGLGDYFFPL-KYGQRLAELFGGPVTFETVPDGRLYFP
TH_3479|M.thermoresistible__bu AIGKWTKPVLVLWGTADDLFPV-SHAQRLAEAFPN-SRLRLIEGSSTYVM
MLBr_00685|M.leprae_Br4923 ELADITVPVLLVLCEKDRVLPPPKYSRHFTDHLPERTQVTKFDGMGHVPM
: *.*: * .:. . . ::. . .
Mflv_3236|M.gilvum_PYR-GCK EDQPAAMAQALR----------DFVSLSPRES
Mvan_5859|M.vanbaalenii_PYR-1 EDQPEIMAQLLR----------DFVG------
MSMEG_6763|M.smegmatis_MC2_155 EDQPEVMAGALR----------EFVG------
Mb0079c|M.bovis_AF2122/97 VDSPDRLADQLS-----------TVAVRT---
Rv0077c|M.tuberculosis_H37Rv VDSPDRLADQLS-----------TVAVRT---
MMAR_0223|M.marinum_M LDRPDRLADLLS-----------AVAVRT---
MUL_4891|M.ulcerans_Agy99 LDRPDRLADLLS-----------AVAVRT---
MAV_5254|M.avium_104 VDQPDRLADLLS-----------TVAVRT---
MAB_2289|M.abscessus_ATCC_1997 DEDADRLLPLLYRHWHSAGRQESSTEVGS---
TH_3479|M.thermoresistible__bu LDHPSETADAIG----------TFIAGRS---
MLBr_00685|M.leprae_Br4923 FEAPEVITKLITNFINQCSKPAEAASPAS---
: . :