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VTSPVDPLLMSVLEASPAVQLDRPEDLTLARESRRHAAPSDAQLPTVGRVKDTSIPVTDAPPIAVRIYWP AGFESAGELPLVLYYHGGGFALGSIDTHDWVARSICAHIEAVVVSVDYRLAPENPYPAAVDDAFAALSWA AEHAPELGADPARIAVAGDSAGGNLATVAAQLAEIRGGPHLKFQLLWYPGTTSDLSLPSVVENADGPVLS RDIMRIFGQAYLGELSETADPTALPFTVAPVNGKLDGLPPAYIATAQHDPLRDDGKIYATRLADAGVPVQ LRNADTLVHGYLDFARIVPAANEEFRLSLDACKTALQASPRPKAGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2039 | - | - | 100% (326) | lipase LipH (carboxylesterase) |
| M. abscessus ATCC 19977 | MAB_2814 | - | 7e-79 | 51.58% (316) | lipase LipH |
| M. abscessus ATCC 19977 | MAB_3270c | - | 8e-51 | 40.38% (317) | lipase/esterase LipN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1434c | lipH | 6e-84 | 51.91% (314) | lipase LipH |
| M. gilvum PYR-GCK | Mflv_3735 | - | 3e-74 | 51.27% (314) | alpha/beta hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv1399c | lipH | 6e-84 | 51.91% (314) | lipase LipH |
| M. leprae Br4923 | MLBr_00314 | - | 4e-16 | 28.31% (272) | putative esterase |
| M. marinum M | MMAR_2208 | lipH | 4e-79 | 50.48% (315) | lipase LipH |
| M. avium 104 | MAV_3377 | - | 8e-77 | 51.59% (314) | alpha/beta hydrolase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3059 | - | 9e-76 | 57.92% (259) | esterase |
| M. thermoresistible (build 8) | TH_3304 | - | 1e-49 | 56.48% (193) | PUTATIVE esterase |
| M. ulcerans Agy99 | MUL_1794 | lipH | 3e-78 | 51.32% (302) | lipase LipH |
| M. vanbaalenii PYR-1 | Mvan_2672 | - | 2e-74 | 52.88% (312) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3059|M.smegmatis_MC2_155 ----------------------------MP--FQLSTADGVEEARRKFSE
TH_3304|M.thermoresistible__bu --------------------------------------------------
Mflv_3735|M.gilvum_PYR-GCK ------------MGMAALDPVLQTVLDAVP--FQLTTDGGPEAARRRFRD
Mvan_2672|M.vanbaalenii_PYR-1 ----------MTVNPATLDAVLQKVLEAVP--FKLTTEGGPEPARQRFKE
MAV_3377|M.avium_104 ----MPRLDNPADEKPGIDPILQKVLDAVP--FRLSTEDGIDAARQRFRD
Mb1434c|M.bovis_AF2122/97 -------MTEPTVARPDIDPVLKMLLDTFP--VTFTAADGVEVARARLRQ
Rv1399c|M.tuberculosis_H37Rv -------MTEPTVARPDIDPVLKMLLDTFP--VTFTAADGVEVARARLRQ
MMAR_2208|M.marinum_M -------MTEQISTRPGIDPILKMLLDAVP--MTFCAADGVELARERLAA
MUL_1794|M.ulcerans_Agy99 -------MTEQISTRPGIDPILKMLLDAVP--MTFCAADGVELARERLAA
MAB_2039|M.abscessus_ATCC_1997 -------------MTSPVDPLLMSVLEASPA-VQLDRPEDLTLARESRRH
MLBr_00314|M.leprae_Br4923 MAISAGAPVEIVESGPSIAARLASLTSRLTIRPILAVGSYVPQLPWPFGL
MSMEG_3059|M.smegmatis_MC2_155 LPRA-EIHPEL-SVHDRTIE-GPAGPIGVRVYRPPTAEG-VKLPVVLFFH
TH_3304|M.thermoresistible__bu --------------------------------------------------
Mflv_3735|M.gilvum_PYR-GCK LPRS-PVHPDV-ETQDRAID-GPAGPIALRIYRPPTEQ--SVLPVVVFLH
Mvan_2672|M.vanbaalenii_PYR-1 LPRN-AILPEV-AAQDLSIE-GPAGPVPVRIYRPPSDE--AAPPTVVFIH
MAV_3377|M.avium_104 LPRR-PLHPEL-RVEDRTIP-GPQGAIAVRIYWPPIHSESRPAPVVLYFH
Mb1434c|M.bovis_AF2122/97 LKTPPELLPEL-RIEERTVGYDGLTDIPVRVYWP-PVVRD-NLPVVVYYH
Rv1399c|M.tuberculosis_H37Rv LKTPPELLPEL-RIEERTVGYDGLTDIPVRVYWP-PVVRD-NLPVVVYYH
MMAR_2208|M.marinum_M LKAPPELLPDL-RTEDRKIGYGELTDIPVRIYWP-TVEPDRVLPVVVYYH
MUL_1794|M.ulcerans_Agy99 LKAPPELLPDL-RTEDRKIGYGELTDIPVRTYWP-TVEPDWVLPVVVYYH
MAB_2039|M.abscessus_ATCC_1997 AAPSDAQLPTVGRVKDTSIPVTDAPPIAVRIYWPAGFESAGELPLVLYYH
MLBr_00314|M.leprae_Br4923 IDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADG--SGRIVLYLH
MSMEG_3059|M.smegmatis_MC2_155 GGGWSVGDLDSYDATARRHAAGAEAVVVSVDYRLAPEHPYPAAVDDVWAA
TH_3304|M.thermoresistible__bu -------------------------------------------VEDCWAA
Mflv_3735|M.gilvum_PYR-GCK GGGWTVGDLDTYDGQARMHAAGAGAVVVSVDYRLAPEHPYPAAVEDVWAA
Mvan_2672|M.vanbaalenii_PYR-1 GGGWTVGDLDSYDGTARLHAAGAGAVVVSVDYRLAPEHPYPAAVDDVWAA
MAV_3377|M.avium_104 GGGFVIGDLDTHDGTARQHAVGAGAIVVSVDYRLAPEHPYPAAVEDAWAA
Mb1434c|M.bovis_AF2122/97 GGGWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAA
Rv1399c|M.tuberculosis_H37Rv GGGWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAA
MMAR_2208|M.marinum_M GGGWALGSLDTHDHVARAHAVGAEAIVVSVDYRLAPEHPYPAGIEDSWAA
MUL_1794|M.ulcerans_Agy99 GGGWALGSLDTHDHVARAHAVGAEAIVVSVDYRLAPEHPYPAGIEDSWAA
MAB_2039|M.abscessus_ATCC_1997 GGGFALGSIDTHDWVARSICAHIEAVVVSVDYRLAPENPYPAAVDDAFAA
MLBr_00314|M.leprae_Br4923 GGAFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDG
::* .
MSMEG_3059|M.smegmatis_MC2_155 TQWVAAHAEELGGDAERLAVAGDSAGGNLAAVVAQLARDAG-----APAL
TH_3304|M.thermoresistible__bu VRWTAAHAAELGGDPARIAVAGDSAGGNLSAVMALLDRDHARADGSAPIL
Mflv_3735|M.gilvum_PYR-GCK TRWVADNADQIGADADRVAVAGDSAGGNLAAVTAQSARDAG------IAL
Mvan_2672|M.vanbaalenii_PYR-1 TRWVAENAAELGADPDRLAVAGDSAGGNLAAVVAQSARDAG------IPL
MAV_3377|M.avium_104 TLWAAENAAGLHGDPGRIAVAGDSAGGTLAAVTAQRARDRG-----GPPV
Mb1434c|M.bovis_AF2122/97 LRWVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGG-----PPL
Rv1399c|M.tuberculosis_H37Rv LRWVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGG-----PPL
MMAR_2208|M.marinum_M LRWVGEHAHELGGDPNRIAVAGDSAGGNISAIMAQLARDHAGN--GAPNL
MUL_1794|M.ulcerans_Agy99 LRWVGEHAHELGGDPNRIAVAGDSAGGNISAIMAQLARDHAGN--GAPNL
MAB_2039|M.abscessus_ATCC_1997 LSWAAEHAPELGADPARIAVAGDSAGGNLATVAAQLAEIRGG-----PHL
MLBr_00314|M.leprae_Br4923 YQWLRR----LGYDPEQIVLAGDSAGGYLALALAQRLQDVGEE--PAALV
* : *. ::.:******* :: * . . :
MSMEG_3059|M.smegmatis_MC2_155 RMQLLWYPATTWDTSLPSFAENADAPVLAIDAVKGFSAWYAGHV-DLTDP
TH_3304|M.thermoresistible__bu RFQLLWYPATTWDTSLPSFSENADAPVLGLDAVAGLSRWYAGHV-DLSDP
Mflv_3735|M.gilvum_PYR-GCK RFQLLWYPSTTFDTSLPSFRENADAPILDLASCKGFSRWYVGDL-DLSGP
Mvan_2672|M.vanbaalenii_PYR-1 RFQLLWYPSTTFDTSLPSFVENAQAPILDLAACKGFTRWYIGDT-DLSEP
MAV_3377|M.avium_104 RFQLLWYPSTMWDASLPSFAENATAPILDVKAVAEFSRWYAGDV-DLSDP
Mb1434c|M.bovis_AF2122/97 VFQLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGL-DISDH
Rv1399c|M.tuberculosis_H37Rv VFQLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGL-DISDH
MMAR_2208|M.marinum_M VFQLLWYPSCVGDLALPSFSENATAPILDLEVIDAFLSWYVPDL-DVSDH
MUL_1794|M.ulcerans_Agy99 VFQLLWYPSCVGDLALPSFSENATAPILDLEVIDAFLSWYVPDL-DVSDH
MAB_2039|M.abscessus_ATCC_1997 KFQLLWYPGTTSDLSLPSVVENADGPVLSRDIMRIFGQAYLGELSETADP
MLBr_00314|M.leprae_Br4923 AISPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKN-KVDDK
:. * . : *. :* * : .
MSMEG_3059|M.smegmatis_MC2_155 ---PATLVPARHDDLSGLAPAYIAVAGHDPLRDDGVHYGDLLAAAGVPVQ
TH_3304|M.thermoresistible__bu ---PVTLVPARADDLSGLPPAYIAVAGHDPLRDDGAKYAELLTAAGVPVE
Mflv_3735|M.gilvum_PYR-GCK SGPPVTLVPARG-DLTGLPPAYIAVAGHDPLRDDGVRYAELLTAAGVPVE
Mvan_2672|M.vanbaalenii_PYR-1 ---PVTLVPARG-NLAGLPPAYIAVAGHDPLRDDGLRYGELLTAAGVPVE
MAV_3377|M.avium_104 ---PADMAPGRATDLSNLPPAYIGVAGYDPLRDDGIRYGERLAAAGVAAQ
Mb1434c|M.bovis_AF2122/97 TMLPTTLAPGNA-DLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVE
Rv1399c|M.tuberculosis_H37Rv TMLPTTLAPGNA-DLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVE
MMAR_2208|M.marinum_M TALPATLAPGNG-DLTGLPPAFIGTAEHDPLRDDGARYAELLTAAGIAAE
MUL_1794|M.ulcerans_Agy99 TALPATLAPGNG-DLTGLPPAFIGTAEHDPLRDDGARYAELLTAAGIAAE
MAB_2039|M.abscessus_ATCC_1997 TALPFTVAPVNG-KLDGLPPAYIATAQHDPLRDDGKIYATRLADAGVPVQ
MLBr_00314|M.leprae_Br4923 ---PEELYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAE
* : .*. : * .: : * .*. . *: .*:..:
MSMEG_3059|M.smegmatis_MC2_155 LDNADTLVHGYLGYSGVVPAATEAFDRGLAALREALHS---------
TH_3304|M.thermoresistible__bu LHNADTLVHGYLGYSGVVPAATEATERALKALRAALHGPGSAS----
Mflv_3735|M.gilvum_PYR-GCK LHHAESLVHGYLGYAGIVPAATEATERGLEALRAALA----------
Mvan_2672|M.vanbaalenii_PYR-1 LHHAESLVHGYLGYAGIVPAATEATERGLAALRAALA----------
MAV_3377|M.avium_104 VHNAETLVHGYLGYAGVVPAATAAMERGLVALRTALQG---------
Mb1434c|M.bovis_AF2122/97 LSNEPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA---------
Rv1399c|M.tuberculosis_H37Rv LSNEPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA---------
MMAR_2208|M.marinum_M WCNEPNLVHGYVSFAVVVPSAAEATSRGLAALRKVLHY---------
MUL_1794|M.ulcerans_Agy99 WCNEPNLVHGYVSFAVVVPSAAEATSRGLATLRKVLHY---------
MAB_2039|M.abscessus_ATCC_1997 LRNADTLVHGYLDFARIVPAANEEFRLSLDACKTALQASPRPKAGP-
MLBr_00314|M.leprae_Br4923 IRVWPGQVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL
** : : :** * : .