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M. thermoresistible (build 8) TH_3304 (-)

annotation: esterase
coordinates: 1710489 - 1711079
length: 197

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3304--100% (197)esterase
M. thermoresistible (build 8)TH_1220lipN8e-3444.10% (195) PROBABLE LIPASE/ESTERASE LIPN
M. thermoresistible (build 8)TH_2802-8e-2642.07% (164) PUTATIVE esterase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1435clipI2e-7064.92% (191) lipase LipH
M. gilvum PYR-GCKMflv_3735-3e-7271.35% (192) alpha/beta hydrolase domain-containing protein
M. tuberculosis H37RvRv1400clipI2e-7064.92% (191) lipase LipH
M. leprae Br4923MLBr_00314-4e-1229.26% (188) putative esterase
M. abscessus ATCC 19977MAB_2814-1e-6462.30% (191) lipase LipH
M. marinum MMMAR_2209lipI8e-6862.83% (191) lipase LipI
M. avium 104MAV_3377-2e-6967.02% (191) alpha/beta hydrolase domain-containing protein
M. smegmatis MC2 155MSMEG_3059-3e-8176.84% (190) esterase
M. ulcerans Agy99MUL_1795lipI9e-6862.83% (191) lipase LipI
M. vanbaalenii PYR-1Mvan_2672-3e-7371.96% (189) alpha/beta hydrolase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3304|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3059|M.smegmatis_MC2_155      ------------------------MPFQLSTADGVEEARRKFSELP--RA
Mb1435c|M.bovis_AF2122/97           MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDDGIEAVRQRLRDLP--RQ
Rv1400c|M.tuberculosis_H37Rv        MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDDGIEAVRQRLRDLP--RQ
MMAR_2209|M.marinum_M               MPSLDKTADEKPAIDPIMQKVLDAVPFRLSTEDGIDAVRQRLRDLP--RR
MUL_1795|M.ulcerans_Agy99           MPSLDKTADEKPAIDPIMQKVLDAVPFRLSTEDGIDAVRQRLRDLP--RR
MAV_3377|M.avium_104                MPRLDNPADEKPGIDPILQKVLDAVPFRLSTEDGIDAARQRFRDLP--RR
Mflv_3735|M.gilvum_PYR-GCK          --------MGMAALDPVLQTVLDAVPFQLTTDGGPEAARRRFRDLP--RS
Mvan_2672|M.vanbaalenii_PYR-1       ------MTVNPATLDAVLQKVLEAVPFKLTTEGGPEPARQRFKELP--RN
MAB_2814|M.abscessus_ATCC_1997      -------MTATAGIDPIIVKILEAVPIQLVSPDGPQASRDAYRAIATARP
MLBr_00314|M.leprae_Br4923          MAISAGAPVEIVESGPSIAARLASLTSRLTIRP-ILAVGSYVPQLPWPFG
                                                                                      

TH_3304|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3059|M.smegmatis_MC2_155      EIHPELSVHDRTIEGPAGPIGVR-----VYRPPTAEG--VKLPVVLFFHG
Mb1435c|M.bovis_AF2122/97           PVHPELRVVDLAIDGPAGPIGTR-----IYWPPTCPDQAE-APVVLYFHG
Rv1400c|M.tuberculosis_H37Rv        PVHPELRVVDLAIDGPAGPIGTR-----IYWPPTCPDQAE-APVVLYFHG
MMAR_2209|M.marinum_M               PVHPELRVEDRAIDGPGGSIPIR-----IYWPPISPDATDPLPVVLFFHG
MUL_1795|M.ulcerans_Agy99           PVHPELRVEDRAIDGPGGSIPIR-----IYWPPISPDATDPLPVVLFFHG
MAV_3377|M.avium_104                PLHPELRVEDRTIPGPQGAIAVR-----IYWPPIHSESRP-APVVLYFHG
Mflv_3735|M.gilvum_PYR-GCK          PVHPDVETQDRAIDGPAGPIALR-----IYRPPTE---QSVLPVVVFLHG
Mvan_2672|M.vanbaalenii_PYR-1       AILPEVAAQDLSIEGPAGPVPVR-----IYRPPSD---EAAPPTVVFIHG
MAB_2814|M.abscessus_ATCC_1997      PWIEVANIEDRTIPGPAGEIPVR-----IYSPAEG----GVRPVFVLIHG
MLBr_00314|M.leprae_Br4923          LIDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADGSGRIVLYLHG
                                                                                      

TH_3304|M.thermoresistible__bu      ------------------------------------------VEDCWAAV
MSMEG_3059|M.smegmatis_MC2_155      GGWSVGDLDSYDATARRHAAGAEAVVVSVDYRLAPEHPYPAAVDDVWAAT
Mb1435c|M.bovis_AF2122/97           GGFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWAAT
Rv1400c|M.tuberculosis_H37Rv        GGFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWAAT
MMAR_2209|M.marinum_M               GGFVMGDLDTHDGTCRQHAVGADTLVVSVDYRLAPEHPYPAAIQDAWAAT
MUL_1795|M.ulcerans_Agy99           GGFVMGDLDTHDGTCRQHAVGADTLVVSVDYRLAPEHPYPAAIQDAWAAT
MAV_3377|M.avium_104                GGFVIGDLDTHDGTARQHAVGAGAIVVSVDYRLAPEHPYPAAVEDAWAAT
Mflv_3735|M.gilvum_PYR-GCK          GGWTVGDLDTYDGQARMHAAGAGAVVVSVDYRLAPEHPYPAAVEDVWAAT
Mvan_2672|M.vanbaalenii_PYR-1       GGWTVGDLDSYDGTARLHAAGAGAVVVSVDYRLAPEHPYPAAVDDVWAAT
MAB_2814|M.abscessus_ATCC_1997      GGWVIGDLDTHDAVARAAAVQADAVVVSVDYRLAPEHPYPAAVEDCWAAL
MLBr_00314|M.leprae_Br4923          GAFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDGY
                                                                              ::*   . 

TH_3304|M.thermoresistible__bu      RWTAAHAAELGGDPARIAVAGDSAGGNLSAVMALLDRDHARADGSAPILR
MSMEG_3059|M.smegmatis_MC2_155      QWVAAHAEELGGDAERLAVAGDSAGGNLAAVVAQLARDAG-----APALR
Mb1435c|M.bovis_AF2122/97           RWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGG-----PPIV
Rv1400c|M.tuberculosis_H37Rv        RWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGG-----PPIV
MMAR_2209|M.marinum_M               RWVADHGSTIGADLNRVAVAGDSAGGTIAAVIAQQARDNADG--PIPPIA
MUL_1795|M.ulcerans_Agy99           RWVADHRSTIGADLNRVAVAGDSAGGTIAAVIAQQARDNADG--PIPPIA
MAV_3377|M.avium_104                LWAAENAAGLHGDPGRIAVAGDSAGGTLAAVTAQRARDRGG-----PPVR
Mflv_3735|M.gilvum_PYR-GCK          RWVADNADQIGADADRVAVAGDSAGGNLAAVTAQSARDAGI------ALR
Mvan_2672|M.vanbaalenii_PYR-1       RWVAENAAELGADPDRLAVAGDSAGGNLAAVVAQSARDAGI------PLR
MAB_2814|M.abscessus_ATCC_1997      QWVHEHAAEIGGDPGRLAVGGDSAGGNLSAVMAQLARDNGID------LA
MLBr_00314|M.leprae_Br4923          QWLRR----LGYDPEQIVLAGDSAGGYLALALAQRLQDVGEE--PAALVA
                                     *       :  *  ::.:.****** :: . *   :* .        : 

TH_3304|M.thermoresistible__bu      FQLLWYPATTWDTSLPSFSENADAPVLGLDAVAGLSRWYAGHVDLSDP--
MSMEG_3059|M.smegmatis_MC2_155      MQLLWYPATTWDTSLPSFAENADAPVLAIDAVKGFSAWYAGHVDLTDP--
Mb1435c|M.bovis_AF2122/97           FQLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNP--
Rv1400c|M.tuberculosis_H37Rv        FQLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNP--
MMAR_2209|M.marinum_M               FQLLWYPSTMWDQTLPSFTENATGEVLDVKAIADFSRWYAGDTDLSNP--
MUL_1795|M.ulcerans_Agy99           FQLLWYPSTMWDQTLPSFTENATGEVLDVKAIADFSRWYAGDTDLSNP--
MAV_3377|M.avium_104                FQLLWYPSTMWDASLPSFAENATAPILDVKAVAEFSRWYAGDVDLSDP--
Mflv_3735|M.gilvum_PYR-GCK          FQLLWYPSTTFDTSLPSFRENADAPILDLASCKGFSRWYVGDLDLSGPSG
Mvan_2672|M.vanbaalenii_PYR-1       FQLLWYPSTTFDTSLPSFVENAQAPILDLAACKGFTRWYIGDTDLSEP--
MAB_2814|M.abscessus_ATCC_1997      FQVLWYPATTFDTTLPSMVENAEAPVLDFKTVGALSKWYLGDTNPATAG-
MLBr_00314|M.leprae_Br4923          ISPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVDDK--
                                    :. *   :.  . : *.   :*      . :   :     .. .      

TH_3304|M.thermoresistible__bu      -PVTLVPARADDLSGLPPAYIAVAGHDPLRDDGAKYAELLTAAGVPVELH
MSMEG_3059|M.smegmatis_MC2_155      -PATLVPARHDDLSGLAPAYIAVAGHDPLRDDGVHYGDLLAAAGVPVQLD
Mb1435c|M.bovis_AF2122/97           -PAPMAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVH
Rv1400c|M.tuberculosis_H37Rv        -PAPMAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVH
MMAR_2209|M.marinum_M               -PAGMAPGRAENLANLPAAYIAVAGHDPLRDDGIRYGELLAAAGVSVEVH
MUL_1795|M.ulcerans_Agy99           -PAGMAPGRAENLANLPAAYIAVAGHDPLRDDGIRYGELLAAAGVSVEVH
MAV_3377|M.avium_104                -PADMAPGRATDLSNLPPAYIGVAGYDPLRDDGIRYGERLAAAGVAAQVH
Mflv_3735|M.gilvum_PYR-GCK          PPVTLVPARGD-LTGLPPAYIAVAGHDPLRDDGVRYAELLTAAGVPVELH
Mvan_2672|M.vanbaalenii_PYR-1       -PVTLVPARGN-LAGLPPAYIAVAGHDPLRDDGLRYGELLTAAGVPVELH
MAB_2814|M.abscessus_ATCC_1997      --PTLVPARAENFEGLAPAFIGTAQFDPLRDDGAKYAELLRDAGVPVQLH
MLBr_00314|M.leprae_Br4923          -PEELYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIR
                                        :         .*. : * .:  : * .*.   .  *  .**..:: 

TH_3304|M.thermoresistible__bu      NADTLVHGYLGYSGVVPAATEATERALKALRAALHGPGSAS----
MSMEG_3059|M.smegmatis_MC2_155      NADTLVHGYLGYSGVVPAATEAFDRGLAALREALHS---------
Mb1435c|M.bovis_AF2122/97           NAQTLVHGYVGYAGVVPAATEATNRGLVALRVVLHG---------
Rv1400c|M.tuberculosis_H37Rv        NAQTLVHGYVGYAGVVPAATEATNRGLVALRVVLHG---------
MMAR_2209|M.marinum_M               NAGSLVHGYIGYAGVVPAATTAMERGLAALRVALHG---------
MUL_1795|M.ulcerans_Agy99           NAGSLVHGYIGYAGVVPAATTAMERGLAALRIALHG---------
MAV_3377|M.avium_104                NAETLVHGYLGYAGVVPAATAAMERGLVALRTALQG---------
Mflv_3735|M.gilvum_PYR-GCK          HAESLVHGYLGYAGIVPAATEATERGLEALRAALA----------
Mvan_2672|M.vanbaalenii_PYR-1       HAESLVHGYLGYAGIVPAATEATERGLAALRAALA----------
MAB_2814|M.abscessus_ATCC_1997      NAPTLIHGYLGYADIVPSATEERDLSLAALKQALHG---------
MLBr_00314|M.leprae_Br4923          VWPGQVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL
                                         :* : . : :** **         :: .