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TEQISTRPGIDPILKMLLDAVPMTFCAADGVELARERLAALKAPPELLPDLRTEDRKIGYGELTDIPVRT YWPTVEPDWVLPVVVYYHGGGWALGSLDTHDHVARAHAVGAEAIVVSVDYRLAPEHPYPAGIEDSWAALR WVGEHAHELGGDPNRIAVAGDSAGGNISAIMAQLARDHAGNGAPNLVFQLLWYPSCVGDLALPSFSENAT APILDLEVIDAFLSWYVPDLDVSDHTALPATLAPGNGDLTGLPPAFIGTAEHDPLRDDGARYAELLTAAG IAAEWCNEPNLVHGYVSFAVVVPSAAEATSRGLATLRKVLHY*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_1794 | lipH | - | 100% (323) | lipase LipH |
M. ulcerans Agy99 | MUL_1795 | lipI | 9e-96 | 54.72% (318) | lipase LipI |
M. ulcerans Agy99 | MUL_1989 | lipN | 3e-45 | 37.97% (316) | lipase/esterase LipN |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1434c | lipH | 1e-143 | 76.71% (322) | lipase LipH |
M. gilvum PYR-GCK | Mflv_3735 | - | 6e-94 | 57.56% (311) | alpha/beta hydrolase domain-containing protein |
M. tuberculosis H37Rv | Rv1399c | lipH | 1e-143 | 76.71% (322) | lipase LipH |
M. leprae Br4923 | MLBr_00314 | - | 3e-15 | 27.23% (224) | putative esterase |
M. abscessus ATCC 19977 | MAB_2814 | - | 7e-87 | 54.29% (315) | lipase LipH |
M. marinum M | MMAR_2208 | lipH | 0.0 | 99.07% (323) | lipase LipH |
M. avium 104 | MAV_3377 | - | 4e-95 | 57.28% (316) | alpha/beta hydrolase domain-containing protein |
M. smegmatis MC2 155 | MSMEG_3059 | - | 2e-87 | 53.97% (302) | esterase |
M. thermoresistible (build 8) | TH_3304 | - | 1e-59 | 59.59% (193) | PUTATIVE esterase |
M. vanbaalenii PYR-1 | Mvan_2672 | - | 2e-88 | 54.34% (311) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MUL_1794|M.ulcerans_Agy99 -------MTEQISTRPGIDPILKMLLDAVPMTFCAADGVELARERLAALK MMAR_2208|M.marinum_M -------MTEQISTRPGIDPILKMLLDAVPMTFCAADGVELARERLAALK Mb1434c|M.bovis_AF2122/97 -------MTEPTVARPDIDPVLKMLLDTFPVTFTAADGVEVARARLRQLK Rv1399c|M.tuberculosis_H37Rv -------MTEPTVARPDIDPVLKMLLDTFPVTFTAADGVEVARARLRQLK Mflv_3735|M.gilvum_PYR-GCK ------------MGMAALDPVLQTVLDAVPFQLTTDGGPEAARRRFRDLP Mvan_2672|M.vanbaalenii_PYR-1 ----------MTVNPATLDAVLQKVLEAVPFKLTTEGGPEPARQRFKELP MSMEG_3059|M.smegmatis_MC2_155 ----------------------------MPFQLSTADGVEEARRKFSELP TH_3304|M.thermoresistible__bu -------------------------------------------------- MAV_3377|M.avium_104 ----MPRLDNPADEKPGIDPILQKVLDAVPFRLSTEDGIDAARQRFRDLP MAB_2814|M.abscessus_ATCC_1997 -----------MTATAGIDPIIVKILEAVPIQLVSPDGPQASRDAYRAIA MLBr_00314|M.leprae_Br4923 MAISAGAPVEIVESGPSIAARLASLTSRLTIRPILAVGSYVPQLPWPFGL MUL_1794|M.ulcerans_Agy99 APPELLPDLR-TEDRKIGYGELTDIPVRTYWP-TVEPDWVLPVVVYYHGG MMAR_2208|M.marinum_M APPELLPDLR-TEDRKIGYGELTDIPVRIYWP-TVEPDRVLPVVVYYHGG Mb1434c|M.bovis_AF2122/97 TPPELLPELR-IEERTVGYDGLTDIPVRVYWP-PVVRD-NLPVVVYYHGG Rv1399c|M.tuberculosis_H37Rv TPPELLPELR-IEERTVGYDGLTDIPVRVYWP-PVVRD-NLPVVVYYHGG Mflv_3735|M.gilvum_PYR-GCK RS-PVHPDVE-TQDRAID-GPAGPIALRIYRPPTEQ--SVLPVVVFLHGG Mvan_2672|M.vanbaalenii_PYR-1 RN-AILPEVA-AQDLSIE-GPAGPVPVRIYRPPSDE--AAPPTVVFIHGG MSMEG_3059|M.smegmatis_MC2_155 RA-EIHPELS-VHDRTIE-GPAGPIGVRVYRPPTAEG-VKLPVVLFFHGG TH_3304|M.thermoresistible__bu -------------------------------------------------- MAV_3377|M.avium_104 RR-PLHPELR-VEDRTIP-GPQGAIAVRIYWPPIHSESRPAPVVLYFHGG MAB_2814|M.abscessus_ATCC_1997 TARPPWIEVANIEDRTIP-GPAGEIPVRIYSP---AEGGVRPVFVLIHGG MLBr_00314|M.leprae_Br4923 IDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADGSGRIVLYLHGG MUL_1794|M.ulcerans_Agy99 GWALGSLDTHDHVARAHAVGAEAIVVSVDYRLAPEHPYPAGIEDSWAALR MMAR_2208|M.marinum_M GWALGSLDTHDHVARAHAVGAEAIVVSVDYRLAPEHPYPAGIEDSWAALR Mb1434c|M.bovis_AF2122/97 GWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALR Rv1399c|M.tuberculosis_H37Rv GWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALR Mflv_3735|M.gilvum_PYR-GCK GWTVGDLDTYDGQARMHAAGAGAVVVSVDYRLAPEHPYPAAVEDVWAATR Mvan_2672|M.vanbaalenii_PYR-1 GWTVGDLDSYDGTARLHAAGAGAVVVSVDYRLAPEHPYPAAVDDVWAATR MSMEG_3059|M.smegmatis_MC2_155 GWSVGDLDSYDATARRHAAGAEAVVVSVDYRLAPEHPYPAAVDDVWAATQ TH_3304|M.thermoresistible__bu -----------------------------------------VEDCWAAVR MAV_3377|M.avium_104 GFVIGDLDTHDGTARQHAVGAGAIVVSVDYRLAPEHPYPAAVEDAWAATL MAB_2814|M.abscessus_ATCC_1997 GWVIGDLDTHDAVARAAAVQADAVVVSVDYRLAPEHPYPAAVEDCWAALQ MLBr_00314|M.leprae_Br4923 AFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDGYQ ::* . MUL_1794|M.ulcerans_Agy99 WVGEHAHELGGDPNRIAVAGDSAGGNISAIMAQLARDHAGN--GAPNLVF MMAR_2208|M.marinum_M WVGEHAHELGGDPNRIAVAGDSAGGNISAIMAQLARDHAGN--GAPNLVF Mb1434c|M.bovis_AF2122/97 WVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGG-----PPLVF Rv1399c|M.tuberculosis_H37Rv WVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGG-----PPLVF Mflv_3735|M.gilvum_PYR-GCK WVADNADQIGADADRVAVAGDSAGGNLAAVTAQSARDAG------IALRF Mvan_2672|M.vanbaalenii_PYR-1 WVAENAAELGADPDRLAVAGDSAGGNLAAVVAQSARDAG------IPLRF MSMEG_3059|M.smegmatis_MC2_155 WVAAHAEELGGDAERLAVAGDSAGGNLAAVVAQLARDAG-----APALRM TH_3304|M.thermoresistible__bu WTAAHAAELGGDPARIAVAGDSAGGNLSAVMALLDRDHARADGSAPILRF MAV_3377|M.avium_104 WAAENAAGLHGDPGRIAVAGDSAGGTLAAVTAQRARDRG-----GPPVRF MAB_2814|M.abscessus_ATCC_1997 WVHEHAAEIGGDPGRLAVGGDSAGGNLSAVMAQLARDNG------IDLAF MLBr_00314|M.leprae_Br4923 WLRR----LGYDPEQIVLAGDSAGGYLALALAQRLQDVGEE--PAALVAI * : *. ::.:.****** :: * :* . : : MUL_1794|M.ulcerans_Agy99 QLLWYPSCVGDLALPSFSENATAPILDLEVIDAFLSWYVPDLDVSDHTAL MMAR_2208|M.marinum_M QLLWYPSCVGDLALPSFSENATAPILDLEVIDAFLSWYVPDLDVSDHTAL Mb1434c|M.bovis_AF2122/97 QLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGLDISDHTML Rv1399c|M.tuberculosis_H37Rv QLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGLDISDHTML Mflv_3735|M.gilvum_PYR-GCK QLLWYPSTTFDTSLPSFRENADAPILDLASCKGFSRWYVGDLDLSGPSGP Mvan_2672|M.vanbaalenii_PYR-1 QLLWYPSTTFDTSLPSFVENAQAPILDLAACKGFTRWYIGDTDLSEP--- MSMEG_3059|M.smegmatis_MC2_155 QLLWYPATTWDTSLPSFAENADAPVLAIDAVKGFSAWYAGHVDLTDP--- TH_3304|M.thermoresistible__bu QLLWYPATTWDTSLPSFSENADAPVLGLDAVAGLSRWYAGHVDLSDP--- MAV_3377|M.avium_104 QLLWYPSTMWDASLPSFAENATAPILDVKAVAEFSRWYAGDVDLSDP--- MAB_2814|M.abscessus_ATCC_1997 QVLWYPATTFDTTLPSMVENAEAPVLDFKTVGALSKWYLGDTNPATAG-- MLBr_00314|M.leprae_Br4923 SPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVDDK--- . * : . : *. :* * : . MUL_1794|M.ulcerans_Agy99 PATLAPGNG-DLTGLPPAFIGTAEHDPLRDDGARYAELLTAAGIAAEWCN MMAR_2208|M.marinum_M PATLAPGNG-DLTGLPPAFIGTAEHDPLRDDGARYAELLTAAGIAAEWCN Mb1434c|M.bovis_AF2122/97 PTTLAPGNA-DLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVELSN Rv1399c|M.tuberculosis_H37Rv PTTLAPGNA-DLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVELSN Mflv_3735|M.gilvum_PYR-GCK PVTLVPARG-DLTGLPPAYIAVAGHDPLRDDGVRYAELLTAAGVPVELHH Mvan_2672|M.vanbaalenii_PYR-1 PVTLVPARG-NLAGLPPAYIAVAGHDPLRDDGLRYGELLTAAGVPVELHH MSMEG_3059|M.smegmatis_MC2_155 PATLVPARHDDLSGLAPAYIAVAGHDPLRDDGVHYGDLLAAAGVPVQLDN TH_3304|M.thermoresistible__bu PVTLVPARADDLSGLPPAYIAVAGHDPLRDDGAKYAELLTAAGVPVELHN MAV_3377|M.avium_104 PADMAPGRATDLSNLPPAYIGVAGYDPLRDDGIRYGERLAAAGVAAQVHN MAB_2814|M.abscessus_ATCC_1997 -PTLVPARAENFEGLAPAFIGTAQFDPLRDDGAKYAELLRDAGVPVQLHN MLBr_00314|M.leprae_Br4923 PEELYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRV : .*. : * .: : * .*. . * .*:..: MUL_1794|M.ulcerans_Agy99 EPNLVHGYVSFAVVVPSAAEATSRGLATLRKVLHY--------- MMAR_2208|M.marinum_M EPNLVHGYVSFAVVVPSAAEATSRGLAALRKVLHY--------- Mb1434c|M.bovis_AF2122/97 EPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA--------- Rv1399c|M.tuberculosis_H37Rv EPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA--------- Mflv_3735|M.gilvum_PYR-GCK AESLVHGYLGYAGIVPAATEATERGLEALRAALA---------- Mvan_2672|M.vanbaalenii_PYR-1 AESLVHGYLGYAGIVPAATEATERGLAALRAALA---------- MSMEG_3059|M.smegmatis_MC2_155 ADTLVHGYLGYSGVVPAATEAFDRGLAALREALHS--------- TH_3304|M.thermoresistible__bu ADTLVHGYLGYSGVVPAATEATERALKALRAALHGPGSAS---- MAV_3377|M.avium_104 AETLVHGYLGYAGVVPAATAAMERGLVALRTALQG--------- MAB_2814|M.abscessus_ATCC_1997 APTLIHGYLGYADIVPSATEERDLSLAALKQALHG--------- MLBr_00314|M.leprae_Br4923 WPGQVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL :* : : :** *: :: .