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M. ulcerans Agy99 MUL_1794 (lipH)

annotation: lipase LipH
coordinates: 1982270 - 1983241
length: 323

TEQISTRPGIDPILKMLLDAVPMTFCAADGVELARERLAALKAPPELLPDLRTEDRKIGYGELTDIPVRT
YWPTVEPDWVLPVVVYYHGGGWALGSLDTHDHVARAHAVGAEAIVVSVDYRLAPEHPYPAGIEDSWAALR
WVGEHAHELGGDPNRIAVAGDSAGGNISAIMAQLARDHAGNGAPNLVFQLLWYPSCVGDLALPSFSENAT
APILDLEVIDAFLSWYVPDLDVSDHTALPATLAPGNGDLTGLPPAFIGTAEHDPLRDDGARYAELLTAAG
IAAEWCNEPNLVHGYVSFAVVVPSAAEATSRGLATLRKVLHY*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1794lipH-100% (323)lipase LipH
M. ulcerans Agy99MUL_1795lipI9e-9654.72% (318) lipase LipI
M. ulcerans Agy99MUL_1989lipN3e-4537.97% (316) lipase/esterase LipN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1434clipH1e-14376.71% (322) lipase LipH
M. gilvum PYR-GCKMflv_3735-6e-9457.56% (311) alpha/beta hydrolase domain-containing protein
M. tuberculosis H37RvRv1399clipH1e-14376.71% (322) lipase LipH
M. leprae Br4923MLBr_00314-3e-1527.23% (224) putative esterase
M. abscessus ATCC 19977MAB_2814-7e-8754.29% (315) lipase LipH
M. marinum MMMAR_2208lipH0.099.07% (323) lipase LipH
M. avium 104MAV_3377-4e-9557.28% (316) alpha/beta hydrolase domain-containing protein
M. smegmatis MC2 155MSMEG_3059-2e-8753.97% (302) esterase
M. thermoresistible (build 8)TH_3304-1e-5959.59% (193) PUTATIVE esterase
M. vanbaalenii PYR-1Mvan_2672-2e-8854.34% (311) alpha/beta hydrolase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1794|M.ulcerans_Agy99           -------MTEQISTRPGIDPILKMLLDAVPMTFCAADGVELARERLAALK
MMAR_2208|M.marinum_M               -------MTEQISTRPGIDPILKMLLDAVPMTFCAADGVELARERLAALK
Mb1434c|M.bovis_AF2122/97           -------MTEPTVARPDIDPVLKMLLDTFPVTFTAADGVEVARARLRQLK
Rv1399c|M.tuberculosis_H37Rv        -------MTEPTVARPDIDPVLKMLLDTFPVTFTAADGVEVARARLRQLK
Mflv_3735|M.gilvum_PYR-GCK          ------------MGMAALDPVLQTVLDAVPFQLTTDGGPEAARRRFRDLP
Mvan_2672|M.vanbaalenii_PYR-1       ----------MTVNPATLDAVLQKVLEAVPFKLTTEGGPEPARQRFKELP
MSMEG_3059|M.smegmatis_MC2_155      ----------------------------MPFQLSTADGVEEARRKFSELP
TH_3304|M.thermoresistible__bu      --------------------------------------------------
MAV_3377|M.avium_104                ----MPRLDNPADEKPGIDPILQKVLDAVPFRLSTEDGIDAARQRFRDLP
MAB_2814|M.abscessus_ATCC_1997      -----------MTATAGIDPIIVKILEAVPIQLVSPDGPQASRDAYRAIA
MLBr_00314|M.leprae_Br4923          MAISAGAPVEIVESGPSIAARLASLTSRLTIRPILAVGSYVPQLPWPFGL
                                                                                      

MUL_1794|M.ulcerans_Agy99           APPELLPDLR-TEDRKIGYGELTDIPVRTYWP-TVEPDWVLPVVVYYHGG
MMAR_2208|M.marinum_M               APPELLPDLR-TEDRKIGYGELTDIPVRIYWP-TVEPDRVLPVVVYYHGG
Mb1434c|M.bovis_AF2122/97           TPPELLPELR-IEERTVGYDGLTDIPVRVYWP-PVVRD-NLPVVVYYHGG
Rv1399c|M.tuberculosis_H37Rv        TPPELLPELR-IEERTVGYDGLTDIPVRVYWP-PVVRD-NLPVVVYYHGG
Mflv_3735|M.gilvum_PYR-GCK          RS-PVHPDVE-TQDRAID-GPAGPIALRIYRPPTEQ--SVLPVVVFLHGG
Mvan_2672|M.vanbaalenii_PYR-1       RN-AILPEVA-AQDLSIE-GPAGPVPVRIYRPPSDE--AAPPTVVFIHGG
MSMEG_3059|M.smegmatis_MC2_155      RA-EIHPELS-VHDRTIE-GPAGPIGVRVYRPPTAEG-VKLPVVLFFHGG
TH_3304|M.thermoresistible__bu      --------------------------------------------------
MAV_3377|M.avium_104                RR-PLHPELR-VEDRTIP-GPQGAIAVRIYWPPIHSESRPAPVVLYFHGG
MAB_2814|M.abscessus_ATCC_1997      TARPPWIEVANIEDRTIP-GPAGEIPVRIYSP---AEGGVRPVFVLIHGG
MLBr_00314|M.leprae_Br4923          IDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADGSGRIVLYLHGG
                                                                                      

MUL_1794|M.ulcerans_Agy99           GWALGSLDTHDHVARAHAVGAEAIVVSVDYRLAPEHPYPAGIEDSWAALR
MMAR_2208|M.marinum_M               GWALGSLDTHDHVARAHAVGAEAIVVSVDYRLAPEHPYPAGIEDSWAALR
Mb1434c|M.bovis_AF2122/97           GWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALR
Rv1399c|M.tuberculosis_H37Rv        GWSLGGLDTHDPVARAHAVGAQAIVVSVDYRLAPEHPYPAGIDDSWAALR
Mflv_3735|M.gilvum_PYR-GCK          GWTVGDLDTYDGQARMHAAGAGAVVVSVDYRLAPEHPYPAAVEDVWAATR
Mvan_2672|M.vanbaalenii_PYR-1       GWTVGDLDSYDGTARLHAAGAGAVVVSVDYRLAPEHPYPAAVDDVWAATR
MSMEG_3059|M.smegmatis_MC2_155      GWSVGDLDSYDATARRHAAGAEAVVVSVDYRLAPEHPYPAAVDDVWAATQ
TH_3304|M.thermoresistible__bu      -----------------------------------------VEDCWAAVR
MAV_3377|M.avium_104                GFVIGDLDTHDGTARQHAVGAGAIVVSVDYRLAPEHPYPAAVEDAWAATL
MAB_2814|M.abscessus_ATCC_1997      GWVIGDLDTHDAVARAAAVQADAVVVSVDYRLAPEHPYPAAVEDCWAALQ
MLBr_00314|M.leprae_Br4923          AFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDGYQ
                                                                             ::*   .  

MUL_1794|M.ulcerans_Agy99           WVGEHAHELGGDPNRIAVAGDSAGGNISAIMAQLARDHAGN--GAPNLVF
MMAR_2208|M.marinum_M               WVGEHAHELGGDPNRIAVAGDSAGGNISAIMAQLARDHAGN--GAPNLVF
Mb1434c|M.bovis_AF2122/97           WVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGG-----PPLVF
Rv1399c|M.tuberculosis_H37Rv        WVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGG-----PPLVF
Mflv_3735|M.gilvum_PYR-GCK          WVADNADQIGADADRVAVAGDSAGGNLAAVTAQSARDAG------IALRF
Mvan_2672|M.vanbaalenii_PYR-1       WVAENAAELGADPDRLAVAGDSAGGNLAAVVAQSARDAG------IPLRF
MSMEG_3059|M.smegmatis_MC2_155      WVAAHAEELGGDAERLAVAGDSAGGNLAAVVAQLARDAG-----APALRM
TH_3304|M.thermoresistible__bu      WTAAHAAELGGDPARIAVAGDSAGGNLSAVMALLDRDHARADGSAPILRF
MAV_3377|M.avium_104                WAAENAAGLHGDPGRIAVAGDSAGGTLAAVTAQRARDRG-----GPPVRF
MAB_2814|M.abscessus_ATCC_1997      WVHEHAAEIGGDPGRLAVGGDSAGGNLSAVMAQLARDNG------IDLAF
MLBr_00314|M.leprae_Br4923          WLRR----LGYDPEQIVLAGDSAGGYLALALAQRLQDVGEE--PAALVAI
                                    *       :  *. ::.:.****** ::   *   :* .        : :

MUL_1794|M.ulcerans_Agy99           QLLWYPSCVGDLALPSFSENATAPILDLEVIDAFLSWYVPDLDVSDHTAL
MMAR_2208|M.marinum_M               QLLWYPSCVGDLALPSFSENATAPILDLEVIDAFLSWYVPDLDVSDHTAL
Mb1434c|M.bovis_AF2122/97           QLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGLDISDHTML
Rv1399c|M.tuberculosis_H37Rv        QLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGLDISDHTML
Mflv_3735|M.gilvum_PYR-GCK          QLLWYPSTTFDTSLPSFRENADAPILDLASCKGFSRWYVGDLDLSGPSGP
Mvan_2672|M.vanbaalenii_PYR-1       QLLWYPSTTFDTSLPSFVENAQAPILDLAACKGFTRWYIGDTDLSEP---
MSMEG_3059|M.smegmatis_MC2_155      QLLWYPATTWDTSLPSFAENADAPVLAIDAVKGFSAWYAGHVDLTDP---
TH_3304|M.thermoresistible__bu      QLLWYPATTWDTSLPSFSENADAPVLGLDAVAGLSRWYAGHVDLSDP---
MAV_3377|M.avium_104                QLLWYPSTMWDASLPSFAENATAPILDVKAVAEFSRWYAGDVDLSDP---
MAB_2814|M.abscessus_ATCC_1997      QVLWYPATTFDTTLPSMVENAEAPVLDFKTVGALSKWYLGDTNPATAG--
MLBr_00314|M.leprae_Br4923          SPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVDDK---
                                    . *   :   . : *.   :*  *         :        .       

MUL_1794|M.ulcerans_Agy99           PATLAPGNG-DLTGLPPAFIGTAEHDPLRDDGARYAELLTAAGIAAEWCN
MMAR_2208|M.marinum_M               PATLAPGNG-DLTGLPPAFIGTAEHDPLRDDGARYAELLTAAGIAAEWCN
Mb1434c|M.bovis_AF2122/97           PTTLAPGNA-DLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVELSN
Rv1399c|M.tuberculosis_H37Rv        PTTLAPGNA-DLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVELSN
Mflv_3735|M.gilvum_PYR-GCK          PVTLVPARG-DLTGLPPAYIAVAGHDPLRDDGVRYAELLTAAGVPVELHH
Mvan_2672|M.vanbaalenii_PYR-1       PVTLVPARG-NLAGLPPAYIAVAGHDPLRDDGLRYGELLTAAGVPVELHH
MSMEG_3059|M.smegmatis_MC2_155      PATLVPARHDDLSGLAPAYIAVAGHDPLRDDGVHYGDLLAAAGVPVQLDN
TH_3304|M.thermoresistible__bu      PVTLVPARADDLSGLPPAYIAVAGHDPLRDDGAKYAELLTAAGVPVELHN
MAV_3377|M.avium_104                PADMAPGRATDLSNLPPAYIGVAGYDPLRDDGIRYGERLAAAGVAAQVHN
MAB_2814|M.abscessus_ATCC_1997      -PTLVPARAENFEGLAPAFIGTAQFDPLRDDGAKYAELLRDAGVPVQLHN
MLBr_00314|M.leprae_Br4923          PEELYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRV
                                       :         .*. : * .:  : * .*.   .  *  .*:..:   

MUL_1794|M.ulcerans_Agy99           EPNLVHGYVSFAVVVPSAAEATSRGLATLRKVLHY---------
MMAR_2208|M.marinum_M               EPNLVHGYVSFAVVVPSAAEATSRGLAALRKVLHY---------
Mb1434c|M.bovis_AF2122/97           EPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA---------
Rv1399c|M.tuberculosis_H37Rv        EPTMVHGYVNFALVVPAAAEATGRGLAALKRALHA---------
Mflv_3735|M.gilvum_PYR-GCK          AESLVHGYLGYAGIVPAATEATERGLEALRAALA----------
Mvan_2672|M.vanbaalenii_PYR-1       AESLVHGYLGYAGIVPAATEATERGLAALRAALA----------
MSMEG_3059|M.smegmatis_MC2_155      ADTLVHGYLGYSGVVPAATEAFDRGLAALREALHS---------
TH_3304|M.thermoresistible__bu      ADTLVHGYLGYSGVVPAATEATERALKALRAALHGPGSAS----
MAV_3377|M.avium_104                AETLVHGYLGYAGVVPAATAAMERGLVALRTALQG---------
MAB_2814|M.abscessus_ATCC_1997      APTLIHGYLGYADIVPSATEERDLSLAALKQALHG---------
MLBr_00314|M.leprae_Br4923          WPGQVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL
                                        :* :   : :** *:         :: .