For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VLPLTGVNVVSLAINLPGPAACARLAEFGAAVTKVEPPGGDPLARAASGWYAELAGRQTVLTLDLKAAAD RATLDELLTGADLLITSMRPTALQRLGLAAPHEQFPRLSLIEIVGHDGDLADEPGHDLNYQAAQGTLTPP HMPRVPLADLLGAERAVSTALAALQARDRSGGGAVFRVALADAAAWAGGAVRHGLMGDNAILGGAFPGYG IYECADGHVALGALESHFYVRTLEIFGADGTHESLRTAFSGKTIAQLEAIAAEADIPLNGVK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1862 | - | - | 100% (272) | hypothetical protein MAB_1862 |
| M. abscessus ATCC 19977 | MAB_0845 | - | 9e-23 | 33.85% (257) | fatty-acid-CoA racemase Far |
| M. abscessus ATCC 19977 | MAB_4651c | - | 2e-15 | 28.77% (292) | putative L-carnitine dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0878 | far | 1e-20 | 33.07% (257) | fatty-acid-CoA racemase |
| M. gilvum PYR-GCK | Mflv_2126 | - | 3e-23 | 35.00% (260) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv0855 | far | 1e-20 | 33.07% (257) | fatty-acid-CoA racemase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4308 | mcr | 5e-23 | 33.72% (261) | alpha-methylacyl-CoA racemase Mcr |
| M. avium 104 | MAV_2704 | - | 1e-105 | 70.00% (270) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_4111 | - | 8e-27 | 35.85% (265) | alpha-methylacyl-CoA racemase |
| M. thermoresistible (build 8) | TH_4477 | - | 1e-22 | 33.85% (260) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_0986 | mcr | 4e-23 | 33.72% (261) | alpha-methylacyl-CoA racemase Mcr |
| M. vanbaalenii PYR-1 | Mvan_4578 | - | 3e-24 | 35.38% (260) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2126|M.gilvum_PYR-GCK --MAGPLQGLRVVELAGIGPGPHAAMIFGDLGADVVRIERPGK-------
Mvan_4578|M.vanbaalenii_PYR-1 --MAGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPGK-------
TH_4477|M.thermoresistible__bu --MAGPLQGLRVVELAGIGPGPHAAMILGDLGADVVRIERPRN-------
MMAR_4308|M.marinum_M --MSGPLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSS-------
MUL_0986|M.ulcerans_Agy99 --MSGPLNGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSS-------
Mb0878|M.bovis_AF2122/97 MTTGGPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPG--------
Rv0855|M.tuberculosis_H37Rv MTTGGPLAGVKVIELGGIGPGPHAGMVLADLGADVVRVRRPG--------
MAB_1862|M.abscessus_ATCC_1997 ---MLPLTGVNVVSLAINLPGPAACARLAEFGAAVTKVEPPGG-------
MAV_2704|M.avium_104 ---MQPLIGVTVVSLAVNLPGPLAAARLAELGAAVTKVEPATG-------
MSMEG_4111|M.smegmatis_MC2_155 MTGTLPLAGIKVLDLSTLLPGPLATLMLAEAGADVIKLERPGRGDEMRTY
** *: *:.*. *** * :.: ** * :: .
Mflv_2126|M.gilvum_PYR-GCK GPGPATKPGG-DYLLRNRRSVAANLKSDEDREMVLRLIAKADVLIEGFRP
Mvan_4578|M.vanbaalenii_PYR-1 GPGPATKPGG-DYLLRNRRSVAANLKSEEDRDMVLRLIAKADVLIEGFRP
TH_4477|M.thermoresistible__bu TPGPGIPRGAKDHLLRNRRSVAADLKTEEGKELVRKLIAKADVLIEGYRP
MMAR_4308|M.marinum_M SAG-GRGGGVKDAMLRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRP
MUL_0986|M.ulcerans_Agy99 SAG-GRGGGVKDAMLRNRRIVTADLKSDQGRELVLKLVAKADVLIEGYRP
Mb0878|M.bovis_AF2122/97 --GLTMPSEDRDLLHRGKRIVDLDVKTQP--QAMLELAAKADVLLDCFRP
Rv0855|M.tuberculosis_H37Rv --GLTMPSEDRDLLHRGKRIVDLDVKTQP--QAMLELAAKADVLLDCFRP
MAB_1862|M.abscessus_ATCC_1997 DPLARAASGWYAELAGRQTVLTLDLKAAADRATLDELLTGADLLITSMRP
MAV_2704|M.avium_104 DPLAAAAPDWYARLIEHQNVLTLDLKDTGDRAKLDELLAGADLLITSMRP
MSMEG_4111|M.smegmatis_MC2_155 EPTFGEASANYAILNRGKRAYAVDFKDPAQRDRVLEIAADADIVMEQFRP
: : :.* : .: : **::: **
Mflv_2126|M.gilvum_PYR-GCK GVTERLGLGPEDCAKVNEKLVYARMTGWGQDGPRAQQAGHDINYISLNGV
Mvan_4578|M.vanbaalenii_PYR-1 GVTERLGLGPHDCAKVNEKLIYARMTGWGQDGPRAQQAGHDINYISLNGA
TH_4477|M.thermoresistible__bu GVTERLGLGPEDCAKINPRLIYGRMTGWGQDGPRAQQAGHDINYISLNGT
MMAR_4308|M.marinum_M GVTERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYISLNGI
MUL_0986|M.ulcerans_Agy99 GVTERLGLGPQDCAKVNDRLIYARMTGWGQAGPRSQQAGHDINYISLNGI
Mb0878|M.bovis_AF2122/97 GTCERLGIGPDDCASVNPRLIFARITGWGQDGPLASTAGHDINYLSQTGA
Rv0855|M.tuberculosis_H37Rv GTCERLGIGPDDCASVNPRLIFARITGWGQDGPLASTAGHDINYLSQTGA
MAB_1862|M.abscessus_ATCC_1997 TALQRLGLAA--PHEQFPRLSLIEIVGH--DGDLADEPGHDLNYQAAQGT
MAV_2704|M.avium_104 SALHRSGLAR--PQQRFPRLSLIEIVGH--HGEHAETPGHDLNYQAAQGT
MSMEG_4111|M.smegmatis_MC2_155 GVAERLGLSYDAMRERNPRIVYCSISGYGPTGQHASRAGHDLNYLAESGL
. .* *:. . :: : * * :. .***:** : *
Mflv_2126|M.gilvum_PYR-GCK LHAIGRHGERPVPPLNLAGDFGGGSMFLLVGVLAALWERERSGKGQVVDA
Mvan_4578|M.vanbaalenii_PYR-1 LHAIGRAGERPVPPLNLVGDFGGGSMFLLVGVLSALYERERSGKGQVVDA
TH_4477|M.thermoresistible__bu LHAVGRKGERPVPPLNLAGDFGGGSMFLLVGILAALFERQTSGKGQVVDA
MMAR_4308|M.marinum_M LHAIGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQVIDA
MUL_0986|M.ulcerans_Agy99 LHAIGRVGERPVPPLNLVGDFGGGSMFLLVGILAALWERHNSGKGQVIDA
Mb0878|M.bovis_AF2122/97 LAAFGYADRPPMPPLNLVADFGGGSMLVLLGIVVALYERERSGVGQVVDA
Rv0855|M.tuberculosis_H37Rv LAAFGYADRPPMPPLNLVADFGGGSMLVLLGIVVALYERERSGVGQVVDA
MAB_1862|M.abscessus_ATCC_1997 L-------TPPHMPRVPLADLLG-AERAVSTALAALQARDRSGGGAVFRV
MAV_2704|M.avium_104 L-------TPPHMPKVPIADVLG-AERAVSSALAALLQAAKAGAGQRYRV
MSMEG_4111|M.smegmatis_MC2_155 LGVVTDANGSPNLPVSVLADIAAGTYPAVMNVLLALRMAERTGEGAHLQV
* * * .*. . : : : ** :* * .
Mflv_2126|M.gilvum_PYR-GCK AMVDGSSVLSMMMWSFRGMGMWSDERGVNMLDTGAPYYDTYECSDGRHIA
Mvan_4578|M.vanbaalenii_PYR-1 AMVDGSSVLSMMMWAFRGMGMWSDERGTNMLDTGAPYYDTYETADGKYVA
TH_4477|M.thermoresistible__bu AMIDGSAVLMQMMWAFRAMGMWSDERGVNMLDTGAPYYDTYETADGKYVA
MMAR_4308|M.marinum_M AMVDGSSVLVQMMWAMRGIGIWSDVRGTNMLDGGAPYYDTYECADGGYVA
MUL_0986|M.ulcerans_Agy99 AMVDGSSVLVQMMWAMRGIGIWSDVRGTNMLDGGAPYYDTYECADGGYVA
Mb0878|M.bovis_AF2122/97 AMVDGVSVLAQMMWTMKGIGSLRDQRESFLLDGGAPFYRCYETSDGKYMA
Rv0855|M.tuberculosis_H37Rv AMVDGVSVLAQMMWTMKGIGSLRDQRESFLLDGGAPFYRCYETSDGKYMA
MAB_1862|M.abscessus_ATCC_1997 ALADAAAWAGG-------AVRHGLMGDNAILGGAFPGYGIYECADG-HVA
MAV_2704|M.avium_104 VLEEAAARAGD-------AVRYGLMGEGAVLGGAYPGYGIYASADG-YVA
MSMEG_4111|M.smegmatis_MC2_155 SMTHNLQVLAYGYIATHQAAGTWPQPSAELLTGGSPRYQIYPAADGRYIA
: . :* . * * * :** ::*
Mflv_2126|M.gilvum_PYR-GCK VGCIEPQFYAEFLKGVGLEGADLPGQNDMGRWPELREAFSKAIAAHDRDH
Mvan_4578|M.vanbaalenii_PYR-1 VGAIEPQFYAEMLKGIGLDGADLPDQNDMSRWPELREAFTKAFAAHDRDH
TH_4477|M.thermoresistible__bu VGAIEPQFYAEMLKGLGLEGEDLPDQNDMSRWDELRARFAEVFKSKDRDH
MMAR_4308|M.marinum_M VGAIEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLTEAFGRYDRDH
MUL_0986|M.ulcerans_Agy99 VGAIEPQFYAAMLAGLGLDAVNLPPQNDVARWPELRAVLTEAFGRYDRDH
Mb0878|M.bovis_AF2122/97 VGAIEPQFFAALLSGLGLSAADVPTQLDVAGYPQMYDIFAERFASRTRDE
Rv0855|M.tuberculosis_H37Rv VGAIEPQFFAALLSGLGLSAADVPTQLDVAGYPQMYDIFAERFASRTRDE
MAB_1862|M.abscessus_ATCC_1997 LGALESHFYVRTLEIFGADG--------------THESLRTAFSGKTIAQ
MAV_2704|M.avium_104 LGAIEPHFFARTCQVFGADG--------------SHESLGAAFAAKTTAE
MSMEG_4111|M.smegmatis_MC2_155 CAALEEKFWQRLVTLVGLDKR---FHDDVGQEQAVTAALTDIFASQPSSY
..:* :*: .* . : :
Mflv_2126|M.gilvum_PYR-GCK WAGVFAGTDACVTPVLSFAEVESEPHNTERDTFYS-ENGSLYPAPAPRFS
Mvan_4578|M.vanbaalenii_PYR-1 WAKVFAGTDACVTPVLSFAEVESEPHNTERDTFYS-ENGSLYPAPAPRFS
TH_4477|M.thermoresistible__bu WAQVFAGTDACVTPVLSFAEVESEAHVVERNTFYR-EGDHLLPAPAPRFS
MMAR_4308|M.marinum_M WAKVFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPAPRFS
MUL_0986|M.ulcerans_Agy99 WAKVFADSDACVTPVLSFGEVHTEPHIAERNTFYEGDDGGPQPMPAPRFS
Mb0878|M.bovis_AF2122/97 WTRVFAGTDACVTPVLAWSEAANNDHLKARSTVIT-AHGVQQAAPAPRFS
Rv0855|M.tuberculosis_H37Rv WTRVFAGTDACVTPVLAWSEAANNDHLKARSTVIT-AHGVQQAAPAPRFS
MAB_1862|M.abscessus_ATCC_1997 LEAIAAEADIPLNGVK----------------------------------
MAV_2704|M.avium_104 LEDLARHMDIPLNEVR----------------------------------
MSMEG_4111|M.smegmatis_MC2_155 WRELLAGEDVCTVVVNTWEEAVEAGHVNINSADRVCVPGDPDLSIPTLTT
: * *
Mflv_2126|M.gilvum_PYR-GCK RSVPSAPKAPGVPGADTEAVLQEWV----
Mvan_4578|M.vanbaalenii_PYR-1 RSAPSAPKPPGVPGADTEAVLREWV----
TH_4477|M.thermoresistible__bu RSVPSAPTPPRDPGADTDAVLQDWQ----
MMAR_4308|M.marinum_M RTVPSRPRPPAAPLTDVEAVLSDWV----
MUL_0986|M.ulcerans_Agy99 RTVPSRPRPPAAPLTDVEAVLSDWA----
Mb0878|M.bovis_AF2122/97 RTPAGPVRPPPAAATPIDEIN--W-----
Rv0855|M.tuberculosis_H37Rv RTPAGPVRPPPAAATPIDEIN--W-----
MAB_1862|M.abscessus_ATCC_1997 -----------------------------
MAV_2704|M.avium_104 -----------------------------
MSMEG_4111|M.smegmatis_MC2_155 SVDPTLRIPDNTRAYPSLAPLPDGHVVWA