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MVTPADIEKWNPDKLLAVIGTAESAHKSLEKLGENYDGTKRSLSDWGGLTAEAWKAQHGKLRTDIAEQGR QAKAVADAMKPLYDEVLAVKREYQDIKGTVERNASFDSSGTTVHWKLNPNGTINTGGASLDYQSAMVKQD LEQRMQNVLARATTVDADIANALRAITSGGMPTIGGQVPADKPKDEPKPAPQDPSMLASGPVGGPDGNPP YPNGATPTMIPGKTIPMADNPPGWDQNMAPGPQRDQAWKDYLSGKNPDGSQRAPGTPPLALPKPEAVSDK GLRVIGAAGRQQGVSYAWGGNKSVGGPTQGTLAGDPPDGGAHRYHDDQRTGFDCGGLVRYSTQQGAGYDV FQRADGLDSGAGTDRIDKSQHLTPVSGGARIPSGKISSIAQSGDILVFETPGSGHEAFSGNNTQHTGIYV GNGYMINAPESGKPVRLDNADEDSRMTDVLRLK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1832 | - | - | 100% (453) | hypothetical protein MAB_1832 |
| M. abscessus ATCC 19977 | MAB_2728c | - | 1e-08 | 28.66% (157) | invasion protein Inv1 |
| M. abscessus ATCC 19977 | MAB_3131c | - | 4e-07 | 29.68% (219) | translation initiation factor IF-2 (InfB) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1514 | - | 4e-10 | 34.21% (152) | invasion protein |
| M. gilvum PYR-GCK | Mflv_2872 | - | 1e-10 | 30.93% (194) | NLP/P60 protein |
| M. tuberculosis H37Rv | Rv1478 | - | 4e-10 | 34.21% (152) | invasion protein |
| M. leprae Br4923 | MLBr_01811 | - | 8e-10 | 35.81% (148) | putative exported p60 protein homologue |
| M. marinum M | MMAR_3234 | - | 6e-09 | 24.92% (321) | hypothetical protein MMAR_3234 |
| M. avium 104 | MAV_2304 | - | 4e-08 | 28.45% (232) | NLP/P60 family protein |
| M. smegmatis MC2 155 | MSMEG_4256 | - | 2e-08 | 22.69% (432) | NLP/P60 family protein |
| M. thermoresistible (build 8) | TH_0436 | - | 2e-08 | 24.38% (320) | Possible inv protein |
| M. ulcerans Agy99 | MUL_1487 | inv2 | 1e-08 | 32.24% (152) | invasion protein Inv2 |
| M. vanbaalenii PYR-1 | Mvan_3652 | - | 3e-09 | 31.36% (169) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
Mflv_2872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0436|M.thermoresistible__bu ----------MALATTINCGSVAVADPGDPNEVATLVAAVANVNQKLQEL
MMAR_3234|M.marinum_M MRLDCRQLTARVIRRSAIGSLASFTALSGFVAAGAMADPAEDALAKLNEL
MAV_2304|M.avium_104 -------------------------------------------MAKLNEL
MSMEG_4256|M.smegmatis_MC2_155 MRHARAHRPTSRFKRPIAGAIASLALGAGLLAGSVQADPADDALAKLNEL
MAB_1832|M.abscessus_ATCC_1997 ----MVTPADIEKWNPDKLLAVIGTAESAHKSLEKLGENYDGTKRSLSDW
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
Mflv_2872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0436|M.thermoresistible__bu GAAVQQKKESVN-KALVDLQEARDAAEAAQAELKAAQESVETANTAIEDA
MMAR_3234|M.marinum_M SRQAEQTTEAMH-SAELDLGAKLAAQQAAENKLTDDQAALDAAKGQLASF
MAV_2304|M.avium_104 SRQAEQTTEAMH-SAQLDLNEKLAAQRAAEKKHDDDQAAVDAAKAHLASY
MSMEG_4256|M.smegmatis_MC2_155 SRQAEQTTEAMH-SAQLDLDNKLAAQQAAEKKHSEDAAAAEQARAQLATF
MAB_1832|M.abscessus_ATCC_1997 GGLTAEAWKAQHGKLRTDIAEQGRQAKAVADAMKPLYDEVLAVKREYQDI
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
Mflv_2872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0436|M.thermoresistible__bu QKRFDTFAAATYVNGPSVSYLTASDPADVLDTAVAGQVLATSAQQVMKNL
MMAR_3234|M.marinum_M QTAVNKVAAAAYMGGRANG-------------------------------
MAV_2304|M.avium_104 QNAVNNLAAATYMGGRVDG-------------------------------
MSMEG_4256|M.smegmatis_MC2_155 QASVNRVAAAQYMGGRTSG-------------------------------
MAB_1832|M.abscessus_ATCC_1997 KGTVERNASFDSSGTTVHWKLN----------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
Mflv_2872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 --------------------------------------MESHVRSKGAPT
TH_0436|M.thermoresistible__bu QQARTEQVNKESLARLAKQRADEKLAAAQASQEAAVNALTEAQETFGAQQ
MMAR_3234|M.marinum_M --------------------MDTILTAPSPQLLIDGLSMQRVMAHQMATQ
MAV_2304|M.avium_104 --------------------MEAILTAGSPQGLIDKLAVQRLMATQMASQ
MSMEG_4256|M.smegmatis_MC2_155 --------------------VDAILTADSPQQLIDQLAVQRVMATEMATQ
MAB_1832|M.abscessus_ATCC_1997 --------------------PNGTINTGGASLDYQSAMVKQDLEQRMQNV
Mb1514|M.bovis_AF2122/97 ---------MRHTRFHPIKLAWITAVVAGLMVGVATPADAEP--------
Rv1478|M.tuberculosis_H37Rv ---------MRHTRFHPIKLAWITAVVAGLMVGVATPADAEP--------
MUL_1487|M.ulcerans_Agy99 ---------MRYKRFRLLGLAWITLAVAALMVVVSAPADADP--------
MLBr_01811|M.leprae_Br4923 ---------MRHKNFRLINLAGLTAMVAGLIIVVTIPATADP--------
Mflv_2872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 ARADRCDPTILVAAQAVRRLSGVIAIVVLLFLACAPVASAQPAA------
TH_0436|M.thermoresistible__bu AELQKLTAEREAAQAKLNEVRTMSAATAGATSGANGSAPAAAPTPGAASG
MMAR_3234|M.marinum_M MSGFRTAREQAAKAEQASEKSAADAKSAAEQAAAVRANLQHKQ-------
MAV_2304|M.avium_104 MKSYRIAGEQAAKAERESAKSAADAKSAAEQAAAVRASLQSKQ-------
MSMEG_4256|M.smegmatis_MC2_155 MQNFRSVGEKAAAAEQASAKSAAEAKTAAEQAAAVRAELQSKQ-------
MAB_1832|M.abscessus_ATCC_1997 LARATTVDADIANALRAITSGGMPTIGGQVPADKPKDEPKPAPQDPSMLA
Mb1514|M.bovis_AF2122/97 ----------------------GQWDPTLPALVS---AGAPGDPLAVANA
Rv1478|M.tuberculosis_H37Rv ----------------------GQWDPTLPALVS---AGAPGDPLAVANA
MUL_1487|M.ulcerans_Agy99 ----------------------GGWDPTLPATAS---AGAPGDALAMANA
MLBr_01811|M.leprae_Br4923 ----------------------GQWDPTLPAAVS---AGAPGDPLAVANA
Mflv_2872|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 ----------------------GPWDPLLPKVAS---AGAPGDPVAIANA
TH_0436|M.thermoresistible__bu TQDPARNWDRAPGGPVVPYGDPSQWDLTLPAIPS---AFVSGDPIAIINA
MMAR_3234|M.marinum_M ----------------------SQLQVQIAVVKSQYLALTPDQRTALADP
MAV_2304|M.avium_104 ----------------------SQLQVQIAVVKSQYMSLTADQRTALANP
MSMEG_4256|M.smegmatis_MC2_155 ----------------------SQLQVQIAIVKSQYEALTPQQREALATA
MAB_1832|M.abscessus_ATCC_1997 SG------------------PVGGPDGNPPYPNGATPTMIPGKTIPMADN
Mb1514|M.bovis_AF2122/97 S--LQATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTGASRIPRA
Rv1478|M.tuberculosis_H37Rv S--LQATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTGASRIPRA
MUL_1487|M.ulcerans_Agy99 S--LQATAQATQTTLDLGRQFLGGLGINLGG--SPAPSAANTGANRIPRV
MLBr_01811|M.leprae_Br4923 S--LQVTAQATQTTLDLGKQFLGRLGINFGGDPSNAATTSSNPGGRIPRV
Mflv_2872|M.gilvum_PYR-GCK --------------MNMGRNFLSSLGI-------VSPAAVPSTSVRGNRV
Mvan_3652|M.vanbaalenii_PYR-1 S--LQATAMATQTAMSMGRNFLSSLGL-------VSPAADPSTSVRGNRV
TH_0436|M.thermoresistible__bu S--LQIAATSAQVTADLGRRFLQRLGL-------VPTPTGYTNEGGIPRV
MMAR_3234|M.marinum_M G-QVPAGLPGAPGPAPEGTPPGGPPPAGAPVPGEAPPPGGVSAMPFTPPD
MAV_2304|M.avium_104 GPAVPAAATAPGAPAPEAAPPGTPP--GGPGPGEAPPPGGAPGMAPGGGG
MSMEG_4256|M.smegmatis_MC2_155 P----PPPAAPPAPAPDALPPANDP-GVLAAPPEGIPPGDIAPPDAAIPG
MAB_1832|M.abscessus_ATCC_1997 PPGWDQNMAPGPQRDQAWKDYLSGKNPD-----GSQRAPGTPPLALPKPE
.
Mb1514|M.bovis_AF2122/97 NARQAVEYVIRRAGSQMGVPYSWGGG-SLQGPSKGVDSGANTVG------
Rv1478|M.tuberculosis_H37Rv NARQAVEYVIRRAGSQMGVPYSWGGG-SLQGPSKGVDSGANTVG------
MUL_1487|M.ulcerans_Agy99 YGRQALEYVIRRGGSQMGVPYSWGGG-SLQGPSKGVDSGANTVG------
MLBr_01811|M.leprae_Br4923 YGGQAIEYVIKRGGAQIGVPYSWGGG-SLQGPSKGVGDGANITG------
Mflv_2872|M.gilvum_PYR-GCK NGAQAIEYVIRRAGTQIGIPYSWGGG-SLAGPSRGVDQGARTVG------
Mvan_3652|M.vanbaalenii_PYR-1 NGAQAIEYVIRRAGTQIGVPYSWGGG-SLTGPSRGVDQGAGTVG------
TH_0436|M.thermoresistible__bu YGRQATEYVIQRAMSQIGVPYSWGGG-NAAGPSRGIDSGANTVG------
MMAR_3234|M.marinum_M GAGGDRAAVVQAALTQVGTPYAWGG--------------AAPGG------
MAV_2304|M.avium_104 VGGGDRATVVQAALTQVGSPYVWGG--------------AAPGG------
MSMEG_4256|M.smegmatis_MC2_155 GPSPVSNTVIQAALSRIGSPYSWGG--------------SGPNA------
MAB_1832|M.abscessus_ATCC_1997 AVSDKGLRVIGAAGRQQGVSYAWGGNKSVGGPTQGTLAGDPPDGGAHRYH
*: . : * .* *** .
Mb1514|M.bovis_AF2122/97 ------FDCSGLVRYAFAG-VGVLIPRFSG--------DQYNAGRHVPPA
Rv1478|M.tuberculosis_H37Rv ------FDCSGLVRYAFAG-VGVLIPRFSG--------DQYNAGRHVPPA
MUL_1487|M.ulcerans_Agy99 ------FDCSGLMRYAFAG-VGVLIPRYSG--------DQYNAGRHISPD
MLBr_01811|M.leprae_Br4923 ------FDCSGLMRYAFAG-VGVLIPRFSG--------DQYNAGRHLTPD
Mflv_2872|M.gilvum_PYR-GCK ------FDCSGLTRFAFAG-VGVLLPRSSG--------DQYDVGRKVPPS
Mvan_3652|M.vanbaalenii_PYR-1 ------FDCSGLTRFAFAG-VGVLLPRWSG--------DQYDAGRKVPPS
TH_0436|M.thermoresistible__bu ------FDCSGLVLYAFAG-VGIKLPHYSG--------AQYNLGRKIPSA
MMAR_3234|M.marinum_M ------FDCSGLVMWAFQQ-AGIALPHSSQ--------ALAHGGQPVSLS
MAV_2304|M.avium_104 ------FDCSGLVMWAFQQ-AGISLPHSSQ--------ALAHGGQPVSLS
MSMEG_4256|M.smegmatis_MC2_155 ------FDCSGLVMWSFQQ-AGISLPHSSQ--------ALARGGQPVSMD
MAB_1832|M.abscessus_ATCC_1997 DDQRTGFDCGGLVRYSTQQGAGYDVFQRADGLDSGAGTDRIDKSQHLTPV
***.** :: .* : : : .: :.
Mb1514|M.bovis_AF2122/97 E-------------AKRGDLIFYGP----------GGGQHVTLYLGNGQM
Rv1478|M.tuberculosis_H37Rv E-------------AKRGDLIFYGP----------GGGQHVTLYLGNGQM
MUL_1487|M.ulcerans_Agy99 Q-------------ARRGDLIFYGP----------GGSQHVTMYLGNGQM
MLBr_01811|M.leprae_Br4923 Q-------------AKRGDLIFYGP----------GGGQHVTMYLGNGQM
Mflv_2872|M.gilvum_PYR-GCK Q-------------AKRGDLLFWGP----------GGSQHEAIYLGGGQM
Mvan_3652|M.vanbaalenii_PYR-1 Q-------------AKRGDLLFWGP----------GGSQHEAIYLGGGQM
TH_0436|M.thermoresistible__bu Q-------------MRRGDVIFYGP----------GGSQHVTIYLGNGQM
MMAR_3234|M.marinum_M D-------------LQPGDVLTFYS----------DAS-HAGIYIGDGLM
MAV_2304|M.avium_104 D-------------LQPGDVLTFYS----------DAS-HAGIYIGDGMM
MSMEG_4256|M.smegmatis_MC2_155 N-------------IQPGDLVTYYS----------DAS-HVGIYIGDGMM
MAB_1832|M.abscessus_ATCC_1997 SGGARIPSGKISSIAQSGDILVFETPGSGHEAFSGNNTQHTGIYVGNGYM
. : **:: : . . * :*:*.* *
Mb1514|M.bovis_AF2122/97 LEASGSAGKVTVSPVRKAGMTPFVTRIIEY
Rv1478|M.tuberculosis_H37Rv LEASGSAGKVTVSPVRKAGMTPFVTRIIEY
MUL_1487|M.ulcerans_Agy99 LEASGSAGKVTVSPVRKAGMTPFVTRIIEY
MLBr_01811|M.leprae_Br4923 LEASSSVGKVTVSSVRKAGMTPFVTRIIES
Mflv_2872|M.gilvum_PYR-GCK IEAQQTGVPIKVSPARTAGTTPYVVRIIET
Mvan_3652|M.vanbaalenii_PYR-1 LEAQQTGVPIKISPVRTSGMTPYVVRIIES
TH_0436|M.thermoresistible__bu IEAPYTGSHVKISPVRTSGMTPYVVRYIEW
MMAR_3234|M.marinum_M VHSSTYGVPVRVVPMNSSGPIYDARRY---
MAV_2304|M.avium_104 IHSSTYGVPVRVVPMNSSGPIYDARRY---
MSMEG_4256|M.smegmatis_MC2_155 VHASTYGSPVRVAPVNN-APIYNVRRY---
MAB_1832|M.abscessus_ATCC_1997 INAPESGKPVRLDNADEDSRMTDVLRLK--
:.: : : . . *