For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPANNSQPRPLSAASRAVHTRRIAFTFDRSAPSRRHFMAGDIAMSHLVALLSGFFPSGEEFFIQSVRRYD RQILDPVLKKQVAGFIGQEMTHGMQHRELNTQLVRRGYWATGLMDRVGTRLVKRMKQHRERMPDTVARAA LAVTAGVEHLTAILGEQVLSVPWIQQQLTDPEVRAMLNWHAIEEMEHKSVAFDVYRYVGGTERMRIAAMV LTLGLFLTRTVILLASIVTDPWAWRRPARTLRSLATLPRTPLFAGLGAKIRCYLRPGFHPDDIDHGPLLE KWREEYFGPEGTLLDHLK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1701 | - | - | 100% (298) | hypothetical protein MAB_1701 |
| M. abscessus ATCC 19977 | MAB_2967c | - | 4e-69 | 50.52% (287) | hypothetical protein MAB_2967c |
| M. abscessus ATCC 19977 | MAB_4451c | - | 2e-68 | 46.69% (287) | hypothetical protein MAB_4451c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2799c | - | 4e-23 | 29.55% (247) | hypothetical protein Mb2799c |
| M. gilvum PYR-GCK | Mflv_4629 | - | 2e-51 | 43.38% (272) | metal-dependent hydrolase |
| M. tuberculosis H37Rv | Rv2777c | - | 4e-23 | 29.55% (247) | hypothetical protein Rv2777c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3143 | - | 1e-53 | 42.86% (273) | hypothetical protein MMAR_3143 |
| M. avium 104 | MAV_3671 | - | 2e-21 | 29.60% (250) | FF domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3675 | - | 6e-20 | 29.24% (277) | metal-dependent hydrolase |
| M. thermoresistible (build 8) | TH_2221 | - | 2e-18 | 28.47% (288) | metal-dependent hydrolase |
| M. ulcerans Agy99 | MUL_2157 | - | 1e-23 | 31.20% (250) | hypothetical protein MUL_2157 |
| M. vanbaalenii PYR-1 | Mvan_0314 | - | 2e-52 | 44.12% (272) | metal-dependent hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2799c|M.bovis_AF2122/97 MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
Rv2777c|M.tuberculosis_H37Rv MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGA
MUL_2157|M.ulcerans_Agy99 --------------------------------------------------
MAV_3671|M.avium_104 --------------------------------------------------
MSMEG_3675|M.smegmatis_MC2_155 --------------------------------------------------
TH_2221|M.thermoresistible__bu --------------------------------------------------
Mflv_4629|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0314|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3143|M.marinum_M --------------------------------------------------
MAB_1701|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2799c|M.bovis_AF2122/97 AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWT---NLPFHYVPNE
Rv2777c|M.tuberculosis_H37Rv AMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWT---NLPFHYVPNE
MUL_2157|M.ulcerans_Agy99 -MFTVDNRAVGPHSGESGAADHERLVLEARDVEFDWA---NLPFHYVPNE
MAV_3671|M.avium_104 -MVIIDNQAAGPHDAS---VDHERLVLEARDVDFDWA---QLPFHYAPGE
MSMEG_3675|M.smegmatis_MC2_155 -MLRPLRFDH--------EIDPGPVQIQARKVHFDLS---DIPLHWIPGH
TH_2221|M.thermoresistible__bu -MLRPRRFAT--------EVDPGPVQIQARQVHFDVS---GIPLHWIPGH
Mflv_4629|M.gilvum_PYR-GCK --MSDDSSTR-------PTTRVVP---KPRRVRFDMP-AETSRQHFVDGD
Mvan_0314|M.vanbaalenii_PYR-1 --MSDDSSTR-------PTTRVVP---KPRRVRFDMP-AGTSRQHFVDGD
MMAR_3143|M.marinum_M --MPEDRAS--------TKSRVLP---KPRRVRFPMP-TSTKRRHFVDGD
MAB_1701|M.abscessus_ATCC_1997 --MPANNSQP-------RPLSAASRAVHTRRIAFTFDRSAPSRRHFMAGD
. ..* : * *: ..
Mb2799c|M.bovis_AF2122/97 PMATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAM
Rv2777c|M.tuberculosis_H37Rv PMATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAM
MUL_2157|M.ulcerans_Agy99 PLPTHVLNVLHLLLPAGEEFFVEVFKKTLPLIKDDQLRLDVQGFIGQEAM
MAV_3671|M.avium_104 PFATHVLNVLHLLLPAGEQFFVEVFKQALPLIRDDQLRLDVQGFIGQEGV
MSMEG_3675|M.smegmatis_MC2_155 PVASTMVNLFNVVLPVAEHWFVDTFNEALPYVRDPKLADDMRGFIGQEAT
TH_2221|M.thermoresistible__bu PVASNLISLLNVVLPDAERWFVATFNEALPYVKDPKLADDMRGFIGQEAT
Mflv_4629|M.gilvum_PYR-GCK LVMSHFVSTLSATFPEGEDFFIRSVREYRDHISDADLKEAVKGFIAQEAT
Mvan_0314|M.vanbaalenii_PYR-1 LVMSHFVSTLSATFPEGEDFFIRSVREYRDHISDADLKEAVKGFIAQEAT
MMAR_3143|M.marinum_M LVMSHFISVLSATFPEGEDFFIRSVKYFQSSIDDPQLLTAVKGFIGQEAT
MAB_1701|M.abscessus_ATCC_1997 IAMSHLVALLSGFFPSGEEFFIQSVRRYDRQILDPVLKKQVAGFIGQEMT
: .: : :* .* :*: .. : * * : ***.**
Mb2799c|M.bovis_AF2122/97 HSQAHSGVVDHFD-AQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWL
Rv2777c|M.tuberculosis_H37Rv HSQAHSGVVDHFD-AQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWL
MUL_2157|M.ulcerans_Agy99 HSQAHSGVLAHFE-AQGVDVTPYTDQIRWLFGKLLAEKPGRNPRQRHRWL
MAV_3671|M.avium_104 HSRAHANVLAHFA-ARGIDLRPYTGQIEWLFGTLLGPRPNWSPRRRQSWL
MSMEG_3675|M.smegmatis_MC2_155 HAETHDKVLEEFLTAHDVHYQPILELVDHVFNTMLAPKPATDPRRRLNDL
TH_2221|M.thermoresistible__bu HADVHEQVMYDFMVEHGVNPEPILAQIEYMFTKVLTPSTSSDPKRRFNNL
Mflv_4629|M.gilvum_PYR-GCK HRHQHRLLNDRLQ----AMGYPTEG-IDRHIKKLVGRLEKR------FSP
Mvan_0314|M.vanbaalenii_PYR-1 HRHQHRLLNDRLQ----AMGYPTEG-IDRHIKKLVGRLEKR------FSP
MMAR_3143|M.marinum_M HRHQHRLLNERLQ----AMGYPTAR-IDRHVARLIKRLERR------FSP
MAB_1701|M.abscessus_ATCC_1997 HGMQHRELNTQLV----RRGYWATGLMDRVGTRLVKRMKQHRERMPDTVA
* * : : : ::
Mb2799c|M.bovis_AF2122/97 LEQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEH
Rv2777c|M.tuberculosis_H37Rv LEQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEH
MUL_2157|M.ulcerans_Agy99 LEQVSFIAAIEHYTAVLGEWILNSPQLDVVGTDPVMLDMLRWHGAEEVEH
MAV_3671|M.avium_104 LEQISLVSAIEHYTAILGEWILDSPAHDRIGTDPVMLDMLRWHGAEEVEH
MSMEG_3675|M.smegmatis_MC2_155 CDRLWLIAAIEHYTAVLGDFVLN-CAWDDHHADPTLTDLFRWHGAEEVEH
TH_2221|M.thermoresistible__bu CERLWLIAALEHYTAVLGDFALN-CRWDDHGAHPTMVDLYRWHGAEEVEH
Mflv_4629|M.gilvum_PYR-GCK KMRLAVTAALEHYTATFAEIILTSDEAQELIGYTEVRPILLWHALEECEH
Mvan_0314|M.vanbaalenii_PYR-1 RMRLAVTAALEHYTATFAEIILTSDEAQELIGDTEVRPILLWHALEECEH
MMAR_3143|M.marinum_M EMRLSMTSALEHYTATLAEIILTSDDAQKLIGQTEVRPILLWHAFEESEH
MAB_1701|M.abscessus_ATCC_1997 RAALAVTAGVEHLTAILGEQVLSVPWIQQQLTDPEVRAMLNWHAIEEMEH
: . :.:** ** :.: * : . : : **. ** **
Mb2799c|M.bovis_AF2122/97 KAVAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPG
Rv2777c|M.tuberculosis_H37Rv KAVAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPG
MUL_2157|M.ulcerans_Agy99 KAVAFDTMKHLRAGYWRQVRAQLAVTPVMLLLWIRGVRFMYTVDPLLAPG
MAV_3671|M.avium_104 KAVAFDTMKHLRAGYWRQVRTQLVVTPAMLLLWIRGVRFMYSRDPYLPPH
MSMEG_3675|M.smegmatis_MC2_155 RSVAHDVAVYFQDSYLARVRAMTIAATAVYMFFQRGTWAMIRKDPTVDIG
TH_2221|M.thermoresistible__bu RNVAHDVAVYFRDSYVDRIRAMCIAMPLMWAFFERGMWYLVKTDPSVELS
Mflv_4629|M.gilvum_PYR-GCK KAVAFDVYETVGGSERTRVWGMRIASLLLFTELVIQTTRSLAG----DRA
Mvan_0314|M.vanbaalenii_PYR-1 KAVAFDVYETVGGSERTRVWGMRIASLLLFSELVIQTTRSLAG----DRA
MMAR_3143|M.marinum_M KAVAFDAYRLIGGTERTRVRGMRIASAILFGELILQTALSMAS----DKA
MAB_1701|M.abscessus_ATCC_1997 KSVAFDVYRYVGGTERMRIAAMVLTLGLFLTRTVILLASIVTD----PWA
: **.*. . :: . .
Mb2799c|M.bovis_AF2122/97 TKPRWRDYFKAARRGLVPGLPRLLRV-VGHYYKPGFHPSQLGGLGAAVDY
Rv2777c|M.tuberculosis_H37Rv TKPRWRDYFKAARRGLVPGLPRLLRV-VGHYYKPGFHPSQLGGLGAAVDY
MUL_2157|M.ulcerans_Agy99 TKPRWRDYVRSARRGLTPGPWRLIRV-VGDYYKPGFHPSQLGGLERAVDY
MAV_3671|M.avium_104 TKPRWRDYFRAAWRGLVPGPLRFVRA-VANYYRPGFHPSQLGGLQRAVDY
MSMEG_3675|M.smegmatis_MC2_155 WWKMHRLRMRDSKLGLLPKFSTLFGTNTLAYCRPSFTPDQMGSTAQAVAY
TH_2221|M.thermoresistible__bu WWQTQRQRCRDSGLGLLPKWRTLFFTNTLDYFRPGFTPEQMGSTAQAVAY
Mflv_4629|M.gilvum_PYR-GCK AYNPVRLLRSLRAFRHNPLFSRAAIERFRSYTHAGFHPDDWDSAEILERW
Mvan_0314|M.vanbaalenii_PYR-1 AYNPVRLLRSLRAFRHNPLFSSAAIERFRSYSRGGFHPDDWDSAEILECW
MMAR_3143|M.marinum_M SYNPVTLVRSLRRFSRTPMFTADALQRFRSYNRPGFHPDDWDSTAVLERW
MAB_1701|M.abscessus_ATCC_1997 WRRPARTLRSLATLPRTPLFAGLG-AKIRCYLRPGFHPDDIDHGPLLEKW
* * : .* *.: . :
Mb2799c|M.bovis_AF2122/97 LAVSPAARASH-------
Rv2777c|M.tuberculosis_H37Rv LAVSPAARASH-------
MUL_2157|M.ulcerans_Agy99 LAVSPAARASH-------
MAV_3671|M.avium_104 LAVSPAARASH-------
MSMEG_3675|M.smegmatis_MC2_155 LASSPAARAAHL------
TH_2221|M.thermoresistible__bu LASSPAARSARL------
Mflv_4629|M.gilvum_PYR-GCK TKELFDADGGQQLRSNV-
Mvan_0314|M.vanbaalenii_PYR-1 TKELFDADGRQQARSSV-
MMAR_3143|M.marinum_M SKELFDQDGSQKVIAQPG
MAB_1701|M.abscessus_ATCC_1997 REEYFGPEGTLLDHLK--
.