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NTGMSPRLDRRELLRLGMTAAAAGFLASCTKNTSGAATSPRVNPDSPRIAAVEAARRGRGAPVRQFALNA GPTELDLAGTRVSTWAYGGRVPGQEIRLRKGEILRVQTVNNLPAPTSVHWHGLALRNDMDGVPGLTQPEI APTGVFDYEFAVPHAGTYWFHPHVGTQIDRGLYAPLIIEDPDEGADYDEELVVALDDWIDGTGTDPDRVL EGLRTKGMPPMDHSMMGGMGADPTAPLGMDAGDVTYPYYLINGRVAADPQAANYRAGQRVRLRMVNAGGD TAFRVGIPGVPMTVTHTDGFPVQPYKADTILVTMGERVDAVVTIPGSSVPLIAVPEGKKGFAQLILRSGD TPVRGRAEDAAMLMKSQVPLDTAMLTAADAVQLTRREPGVIHDVRLAGPGGKYTWTINGKTYDPRDGLPV REGQRVRLRFINNSMMFHPMHLHGHTFAVRDGKGAFRARKDTVLVAPMKTVEVDFDADNPGQWLTHCHNI YHGETGMMAVVSYMQD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1271c | - | - | 100% (507) | oxidase (copper-binding protein) |
| M. abscessus ATCC 19977 | MAB_0463c | - | 0.0 | 68.45% (504) | oxidase (copper-binding protein) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0869c | - | 1e-108 | 43.65% (504) | oxidase |
| M. gilvum PYR-GCK | Mflv_3489 | - | 2e-08 | 23.33% (180) | multicopper oxidase, type 3 |
| M. tuberculosis H37Rv | Rv0846c | - | 1e-108 | 44.16% (505) | oxidase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4770 | - | 1e-103 | 39.78% (548) | oxidase |
| M. avium 104 | MAV_3048 | - | 1e-39 | 28.54% (459) | multicopper oxidase family protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0341 | - | 1e-103 | 39.60% (548) | oxidase |
| M. vanbaalenii PYR-1 | Mvan_3672 | - | 1e-115 | 44.75% (514) | multicopper oxidase, type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0869c|M.bovis_AF2122/97 -------------------MPELATSGNA-FDKRRFSRRGFLGAGIASG-
Rv0846c|M.tuberculosis_H37Rv -------------------MPELATSGNA-FDKRRFSRRGFLGAGIASG-
MMAR_4770|M.marinum_M -------------------MPVLPTGGHP-FGSAQLSRRGFIGAGIAGG-
MUL_0341|M.ulcerans_Agy99 -------------------MPVLPTGGHP-FGSAQLSRRGFIGAGIAGG-
Mvan_3672|M.vanbaalenii_PYR-1 ------------------------MNRQS-VGTKILTRRTFLAATLAAST
MAB_1271c|M.abscessus_ATCC_199 ----------------------MNTGMSPRLDRRELLRLGMTAA--AAG-
MAV_3048|M.avium_104 --------------------------MMVAVTRRDFCKWGGIAALAACA-
Mflv_3489|M.gilvum_PYR-GCK MKRSSWHLRAGSVVLGWLVALVMAAIAHPYIALSNWLLIHLLGLGAASNA
. . *
Mb0869c|M.bovis_AF2122/97 FALAAC-ASKP---TASGA-----------------------------AG
Rv0846c|M.tuberculosis_H37Rv FALAAC-ASKP---TASGA-----------------------------AG
MMAR_4770|M.marinum_M LALAGCGHSQT---TQTGE-----------------------------TA
MUL_0341|M.ulcerans_Agy99 LALAGCGHSQT---TQTGE-----------------------------TA
Mvan_3672|M.vanbaalenii_PYR-1 AAMAACGKPTS---VNP---------------------------------
MAB_1271c|M.abscessus_ATCC_199 -FLASCTKNTSGAATSPRV-----------------------------NP
MAV_3048|M.avium_104 --------------------------------------------------
Mflv_3489|M.gilvum_PYR-GCK ILIWSRHFADALLRRSPDPPYPGQVIRLLAFNIGAVTVITGMLGGWWPVV
Mb0869c|M.bovis_AF2122/97 MTAAIDAAEAARPHSGRTV-TATLTPQP---ARIDLGGPIVSTLTYGNTI
Rv0846c|M.tuberculosis_H37Rv MTAAIDAAEAARPHSGRTV-TATLTPQP---ARIDLGGPIVSTLTYGNTI
MMAR_4770|M.marinum_M MADAIAAAERARPHTGRTV-TASLTPQQ---AQIDLGGPVVQTLAFGNTV
MUL_0341|M.ulcerans_Agy99 MADAIAAAERARPHTGRTV-TASLTPQQ---AQIDLGGPVVQTLAFGNTV
Mvan_3672|M.vanbaalenii_PYR-1 ATDPIAVAEAARPHTGRTV-TAALTPGP---ADIDLGGPVARTLAYNNSV
MAB_1271c|M.abscessus_ATCC_199 DSPRIAAVEAARRGRGAPVRQFALNAGP---TELDLAGTRVSTWAYGGRV
MAV_3048|M.avium_104 -----------GPPHGKADYTLRIATGT---VELAPG-RVVSTLTYNGQF
Mflv_3489|M.gilvum_PYR-GCK LAGGVLVAAVAAVHAGDLMRFLRAALPARFSITVHYYVAAAACLAVGAGL
* : . : . .
Mb0869c|M.bovis_AF2122/97 PGPLIRATVGDEIVVSVTNRLGDPTSVHWHGIALRNDMDGTEPAT-ANIG
Rv0846c|M.tuberculosis_H37Rv PGPLIRATVGDEIVVSVTNRLGDPTSVHWHGIALRNDMDGTEPAT-ANIG
MMAR_4770|M.marinum_M PGPLIRASVGDEVVVAVSNRLDRATSVHWHGIALRNDMDGAEPAT-PNIG
MUL_0341|M.ulcerans_Agy99 PGPLIRASVGDEVVVAVSNRLDRTTSVHWHGIALRNDMDGAEPAT-PNIG
Mvan_3672|M.vanbaalenii_PYR-1 PGPLIRANVGDELAISVTNGLDHPSSLHWHGIALRNDMDGATPAT-PNID
MAB_1271c|M.abscessus_ATCC_199 PGQEIRLRKGEILRVQTVNNLPAPTSVHWHGLALRNDMDGVPGLTQPEIA
MAV_3048|M.avium_104 PGPLLRFMQGRRTWVDVYNDTDAPEQLHWHGQHIGADVDGAAEEGTPYVP
Mflv_3489|M.gilvum_PYR-GCK GVAMANSALPGILAERFRTAHAVLNLFGWVGLTVLGTLVTLWPTMLRTRM
. . . * * : :
Mb0869c|M.bovis_AF2122/97 PG----------GDFTYRFSVPDPGTYWAHPHVGLQGDH------GLYLP
Rv0846c|M.tuberculosis_H37Rv PG----------GDFTYRFSVPDPGTYWAHPHVGLQGDH------GLYLP
MMAR_4770|M.marinum_M AD----------QDFTYRFSVPNAGTYWAHPHVGLEDDH------GLYLP
MUL_0341|M.ulcerans_Agy99 AD----------QDFTYRFSVPNAGTYWAHPHVGLEDDH------GLYLP
Mvan_3672|M.vanbaalenii_PYR-1 PS----------STFTYRFSAPHPGTYWAHPHTGLDADY------GLYAP
MAB_1271c|M.abscessus_ATCC_199 PT----------GVFDYEFAVPHAGTYWFHPHVGTQIDR------GLYAP
MAV_3048|M.avium_104 AH----------GMRRISFVPGPAGFRFYHTHVVPRADLSRGQYSGLVGP
Mflv_3489|M.gilvum_PYR-GCK ADGVERAARRGLPALVLSVAVAVAGAILGSSRVVGVGALSFLTAVGFVLW
. . .* .:. *:
Mb0869c|M.bovis_AF2122/97 VVVDDPTE--PGHYDAEWIIILDDWTDG---------------------I
Rv0846c|M.tuberculosis_H37Rv VVVDDPTE--PGHYDAEWIIILDDWTDG---------------------I
MMAR_4770|M.marinum_M FIVDDPTE--PNRYDAEWIVVLDDWTDG---------------------V
MUL_0341|M.ulcerans_Agy99 FIVDDPTE--PNRYDAEWIVVLDDWTDG---------------------V
Mvan_3672|M.vanbaalenii_PYR-1 VIIDDAAE--PGRYDAEWIVVLDDWTDG---------------------I
MAB_1271c|M.abscessus_ATCC_199 LIIEDPDE--GADYDEELVVALDDWIDG---------------------T
MAV_3048|M.avium_104 VHIASKDDD-AGAFDQETFLTLKEFEPS---------------------L
Mflv_3489|M.gilvum_PYR-GCK PHIDEVRRKRPADFPTLSVLCGVVWLAGSLGYLSVGLLTAPNSMAAATVT
: . : .: : .
Mb0869c|M.bovis_AF2122/97 GKSPQQLYGELTDPN--------KPTMQNT--------------------
Rv0846c|M.tuberculosis_H37Rv GKSPQQLYGELTDPN--------KPTMQNT--------------------
MMAR_4770|M.marinum_M GKSPQQLFDALVDPN--------KPRMQELPGSSTAPSTSTST-------
MUL_0341|M.ulcerans_Agy99 GKSPQQLFDAFVDPN--------KPRMQELPGSSTAPSTSTST-------
Mvan_3672|M.vanbaalenii_PYR-1 GSSPQQLYDGLRPVTGAGGHSGGMPGMSGTPG------------------
MAB_1271c|M.abscessus_ATCC_199 GTDPDRVLEGLRTKG--------MPPMDHS--------------------
MAV_3048|M.avium_104 SRGGDMAVDFLAGAQEPDLRER----------------------------
Mflv_3489|M.gilvum_PYR-GCK AAAGPALLAGFLVQVLFGSLAYLIPMVVGGRASALAATAELERGAPWRLS
. :
Mb0869c|M.bovis_AF2122/97 ----------------------------------------------TGMP
Rv0846c|M.tuberculosis_H37Rv ----------------------------------------------TGMP
MMAR_4770|M.marinum_M ---------------TTTTTTPTTKTSTTTTTTGTSKTSPTTTTSATGKP
MUL_0341|M.ulcerans_Agy99 ---------------TTTTTTPTTKTSTTTTTTGTSKTSPTTTTSATGKP
Mvan_3672|M.vanbaalenii_PYR-1 ---------------------------------------------MPGVP
MAB_1271c|M.abscessus_ATCC_199 ---------------------------------------------MMGGM
MAV_3048|M.avium_104 -----------------------------------------------GES
Mflv_3489|M.gilvum_PYR-GCK VANFGLLICVLPVPNLVRVAVSALVLVAYGAFLPLLVRAVWLAQRNTGVR
*
Mb0869c|M.bovis_AF2122/97 E---GEGVDSNLLGGDGGDIAYPYYLINGRIPVAATSFKAKPGQRIRIRI
Rv0846c|M.tuberculosis_H37Rv E---GEGVDSNLLGGDGGDIAYPYYLINGRIPVAATSFKAKPGQRIRIRI
MMAR_4770|M.marinum_M DEESGEVGSSDLLGGDAGDIAYPYYLVNGRIPAAPTSFKAKPGQRIRIRI
MUL_0341|M.ulcerans_Agy99 DEESGEVGSSDLLGGDAGDIAYPYYLVNGRIPAAPTSFKAKPGQRIRIRI
Mvan_3672|M.vanbaalenii_PYR-1 G--VGGVGASQLLGGDAGDVSYPFYLANGRIPAAPTTLTARPGQRIRMRI
MAB_1271c|M.abscessus_ATCC_199 G-----ADPTAPLGMDAGDVTYPYYLINGRVAADPQAANYRAGQRVRLRM
MAV_3048|M.avium_104 S----MAASRGRGEQPGYEVGYRAFAINGRMLGHGDPIRVRTGQLVLLHV
Mflv_3489|M.gilvum_PYR-GCK STPGRLDPPPLRQRLGIAAAGFGVVILTAAAGVAADPATLGIGSAPTVTA
: .. . *. :
Mb0869c|M.bovis_AF2122/97 INSAADTAFRIALAGH-----SMTVTHTDGYPVIP----TEVDALLIGMA
Rv0846c|M.tuberculosis_H37Rv INSAADTAFRIALAGH-----SMTVTHTDGYPVIP----TEVDALLIGMA
MMAR_4770|M.marinum_M INVASDTAFRVALAGH-----TMTVTHTDGYPVIP----TQVDALLIGMA
MUL_0341|M.ulcerans_Agy99 INVASDTAFRVALAGH-----TMTVTHTDGYPVIP----TQVDALLIGMA
Mvan_3672|M.vanbaalenii_PYR-1 INAASDTAFRVALAGH-----RMTVTHTDGFPVVP----TEVDALLIGMG
MAB_1271c|M.abscessus_ATCC_199 VNAGGDTAFRVGIPGV-----PMTVTHTDGFPVQP----YKADTILVTMG
MAV_3048|M.avium_104 LNAGATETRSLALPGH-----AFTVVALDGNPVPNR---APVPVLWLGAG
Mflv_3489|M.gilvum_PYR-GCK APTGHTTEVRVRVDGMRYVPDTITVPAGDRLRITFHNTGTDRHDLVLANG
. : : * :** * : : : .
Mb0869c|M.bovis_AF2122/97 ERYDVMVTAAG-GVFPLVALA---------EGKNALARALLSTGAGSP--
Rv0846c|M.tuberculosis_H37Rv ERYDVMVTAAG-GVFPLVALA---------EGKNALARALLSTGAGSP--
MMAR_4770|M.marinum_M ERYDVIVTAAD-GVFPLVASA---------EGKNALARALLSTGSGTA--
MUL_0341|M.ulcerans_Agy99 ERYDVIVTAAD-GVFPLVASA---------EGKNALARALLSTGSGTA--
Mvan_3672|M.vanbaalenii_PYR-1 ERYDALITTGD-GVFPFVASA---------EGKNALARALLSTGAGAA--
MAB_1271c|M.abscessus_ATCC_199 ERVDAVVTIPG-SSVPLIAVP---------EGKKGFAQLILRSGDTPV--
MAV_3048|M.avium_104 ERVSALVSMTNPGVWVLGDLS---------DDDREHGLGVVVEYAGRA--
Mflv_3489|M.gilvum_PYR-GCK ARTDRVAPGVT-AVLDAGVIGSDLAGWCSIAGHRQMGMTLTIKAIGTPPV
* . : . . ... . :
Mb0869c|M.bovis_AF2122/97 -----------PDPQFRPDELNWRVG--TVEMFTAATTANLGRPEPTHDL
Rv0846c|M.tuberculosis_H37Rv -----------PDPQFRPDELNWRVG--TVEMFTAATTANLGRPEPTHDL
MMAR_4770|M.marinum_M -----------PDPQFRPAELNKRVG--TVEMFTATTAVNLGRPDPQMSL
MUL_0341|M.ulcerans_Agy99 -----------PDPQFRPAELNKRVG--TVEMFTATTAVNLGRPDPQMSL
Mvan_3672|M.vanbaalenii_PYR-1 -----------PDPTFMPPELQRRVG--TVGVFTAAPEAVLDVSRADVAL
MAB_1271c|M.abscessus_ATCC_199 -----------RGRAEDAAMLMKSQVPLDTAMLTAADAVQLTRREPGVIH
MAV_3048|M.avium_104 -----------GEPQWVPPPPFTWDY----RLFAGPHPAPVAPPDHTIDL
Mflv_3489|M.gilvum_PYR-GCK SGHEHELPGHGPDPSLTATDIARSLGGRPGPGFAARDPKLSAAETAEHRV
. ::.
Mb0869c|M.bovis_AF2122/97 PVTLGGTMAK--YDWTINGEPHSTTNP---LHVRLGQRPTLMFDNTTMMY
Rv0846c|M.tuberculosis_H37Rv PVTLGGTMAK--YDWTINGEPYSTTNP---LHVRLGQRPTLMFDNTTMMY
MMAR_4770|M.marinum_M PITLGGTMAK--YDWTINGEPYSKTHP---LTVRLGERPTLMFDNPTMMY
MUL_0341|M.ulcerans_Agy99 PITLGGTMAK--YDWTINGEPYSKTHP---LTVRLGERPTLMFDNPTMMY
Mvan_3672|M.vanbaalenii_PYR-1 SARLSGSMAS--YDWTINGRPFEDTVP---LTVMQGQKATLTFTNTTMMW
MAB_1271c|M.abscessus_ATCC_199 DVRLAGPGGK--YTWTINGKTYDPRDG---LPVREGQRVRLRFINNSMMF
MAV_3048|M.avium_104 LIEKRNAADNGFNVWTVNGTPFAMDSNQPVLDVERGRRYRLRLRNASDDL
Mflv_3489|M.gilvum_PYR-GCK TLTVSEVEREVSPGITQRLWTFGGSAPGPTLRGRVGDVFEITLINDGTIG
. * . .. * * : : *
Mb0869c|M.bovis_AF2122/97 HPIHLHGHTFQMIKADGSPGA-----------------------------
Rv0846c|M.tuberculosis_H37Rv HPIHLHGHTFQMIKADGSPGA-----------------------------
MMAR_4770|M.marinum_M HPIHLHGHTFQMIKPDGTPGA-----------------------------
MUL_0341|M.ulcerans_Agy99 HPIHLHGHTFQMIKPDGTPGA-----------------------------
Mvan_3672|M.vanbaalenii_PYR-1 HPMHLHGHTFQVIKPDGTPGP-----------------------------
MAB_1271c|M.abscessus_ATCC_199 HPMHLHGHTFAVRDGKGAFRA-----------------------------
MAV_3048|M.avium_104 HPMHLHRHTFEITRFAGTPTAGV---------------------------
Mflv_3489|M.gilvum_PYR-GCK HSIDFHAGSLAPDRPMRTIEPGAQLVYRFTATRAGVWLYHCATMPMSVHI
*.:.:* :: : .
Mb0869c|M.bovis_AF2122/97 ------------------RKDTVIVLPKQKMRAV--------LVADNPGV
Rv0846c|M.tuberculosis_H37Rv ------------------RKDTVIVLPKQKMRAV--------LVADNPGV
MMAR_4770|M.marinum_M ------------------RKDTVIVLPGQQLRAV--------LVADNPGY
MUL_0341|M.ulcerans_Agy99 ------------------RKDTVIVLPGQQLRAV--------LVADNPGY
Mvan_3672|M.vanbaalenii_PYR-1 ------------------RKDTVIVLPMQELTVA--------LAADNPGV
MAB_1271c|M.abscessus_ATCC_199 ------------------RKDTVLVAPMKTVEVD--------FDADNPGQ
MAV_3048|M.avium_104 ------------------RKDVAMLGGYQSMEID--------FVADQPGL
Mflv_3489|M.gilvum_PYR-GCK ANGMFGAVVIDPPDLSTVDREYLMVQSEFYLGADGGEVDADKVAADTPDL
:: :: : . ** *.
Mb0869c|M.bovis_AF2122/97 WVMHCHNNYHQVAGMATRLDYIL---------------------------
Rv0846c|M.tuberculosis_H37Rv WVMHCHNNYHQVAGMATRLDYIL---------------------------
MMAR_4770|M.marinum_M WVLHCHNSYHREAGMMTLLDYIF---------------------------
MUL_0341|M.ulcerans_Agy99 WVLHCHNSYHREAGMMTLLDYIF---------------------------
Mvan_3672|M.vanbaalenii_PYR-1 WMMHCHNTYHQEAGMMTSLNYSPQPGAAPSHGQRQ---------------
MAB_1271c|M.abscessus_ATCC_199 WLTHCHNIYHGETGMMAVVSYMQD--------------------------
MAV_3048|M.avium_104 SLLHCHQQIHMDYGLMLLLNGV----------------------------
Mflv_3489|M.gilvum_PYR-GCK VVFNGYAQQYDHAPLTARVGERVRIWVLAAGPNRGSAFHVVGGQFDTVWA
: : : : : :.
Mb0869c|M.bovis_AF2122/97 --------------------------------------------------
Rv0846c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4770|M.marinum_M --------------------------------------------------
MUL_0341|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3672|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1271c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3048|M.avium_104 --------------------------------------------------
Mflv_3489|M.gilvum_PYR-GCK EGAYRLRPGAGGSQTLGLFPAQGGFVELSFPEPGNYPFVSHAMVDAERGA
Mb0869c|M.bovis_AF2122/97 --------
Rv0846c|M.tuberculosis_H37Rv --------
MMAR_4770|M.marinum_M --------
MUL_0341|M.ulcerans_Agy99 --------
Mvan_3672|M.vanbaalenii_PYR-1 --------
MAB_1271c|M.abscessus_ATCC_199 --------
MAV_3048|M.avium_104 --------
Mflv_3489|M.gilvum_PYR-GCK HGVIAVGN