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VLLTFLDSLKGEVAVLSKRHRKSSKKVVVQRTVTAAGAVAATASLAFVGPTAQAAAAAPDYKGAVTDYKN ALNNYLSGTNAIGTAAGGVWNPLAQGSGGLLPTFGTSLTHSNLTKIGDLPDVLRNLASTPLPTAVPGVIP AIKIPGQGFVDLPLPTTIPGASVLNGLANALDGVFNNPVIGPIVNRLPPLSDIVDGLIAEQDTFTAGYNW PLLQASGLTTITNTFVQTPSGLNIKIPAALDPLGILPDSVRILPDGTLPNVTAWVPMGAGNYTFPLGMET GWWATAPTLIVDGGAVNVPQTVLSIPMWANGIKAPLGLGQAGQFNAHVLIPTQNGIYSPIGTTLSNFSIP VLGLGMTNLNVTTGNYLGTNGFNVNNGQNVMVLQTPFSGALPVPLVYSLGGFNFGTEGAGFTLPSLFGVG LMPSFQLGTAPGANTPLGVIPPNLIPTGAVVPTQLITVSGLISTALGIPDPTVELAKALTPLYKGLVTPA LTPISDLLTQQYGNLFNGAASNTLQASKFYKDVMTQLGGLIGAAPLSSPVPKALAAADIQAPAAEHVAAP APAAKEPTGPAAPEVKQLEAPKPDITSNLVATKERIVEKVTSTTLSVSAPTVPEQSVVSVGETATSPAAE PVKNVAKEAPKAEVKDAKEADKPAKPVVKEKLQDKVDKATQALKDSATGSIKQTRGAITSTITNTAESAT SAVTGGGTSAAAAEGTKDAKAKDSDSGKHHEDGSAGSPNKVKVKTPSESGGKHRAPDASGGGSSGSNAGG GSDGSGSHGGSGAGGGKHSAGD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1013 | - | - | 100% (792) | hypothetical protein MAB_1013 |
| M. abscessus ATCC 19977 | MAB_0978 | - | 2e-11 | 22.68% (807) | hypothetical protein MAB_0978 |
| M. abscessus ATCC 19977 | MAB_0974 | - | 2e-11 | 23.84% (344) | hypothetical protein MAB_0974 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 2e-07 | 30.36% (112) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-09 | 31.90% (116) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 1e-07 | 35.23% (88) | PE-PGRS family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0884 | - | 9e-09 | 23.55% (259) | hypothetical protein MMAR_0884 |
| M. avium 104 | MAV_4827 | - | 2e-07 | 24.24% (264) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0204 | - | 1e-81 | 32.33% (733) | hypothetical protein MSMEG_0204 |
| M. thermoresistible (build 8) | TH_4162 | - | 3e-07 | 27.27% (198) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1721 | - | 3e-07 | 30.56% (108) | PE_PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 6e-08 | 33.33% (120) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------MMFLAPPGGPGPISAAIQLTSTGSEATEPW
Rv3508|M.tuberculosis_H37Rv MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSAR
Mb1485c|M.bovis_AF2122/97 MSLVIVAPETVAAAALDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAA
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -MVTFG--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 YVVSFG--------------------------------------------
Rv3508|M.tuberculosis_H37Rv IAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAAAAEQIVL
Mb1485c|M.bovis_AF2122/97 IATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYVSAEATNAAPLAT
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------------------GGATPTP-----------TSLGAAAVDLSGTS
Mvan_1264|M.vanbaalenii_PYR-1 ------------------GSGAPTP-----------NNLAASLVDLSGTS
Rv3508|M.tuberculosis_H37Rv GVINAPTQALLGRPLIGDGANATTPGGAGGAGGLLFGNGGAGAAGAPGQA
Mb1485c|M.bovis_AF2122/97 LEHN-----------VLNALNAPTQALLG------RPLIGDGAAGAPGTG
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------CGLICNG-----------QDGTGQNGGILFGNGGSGWNSDVVGM
Mvan_1264|M.vanbaalenii_PYR-1 ------CGLICNG-----------QDGTGQNGGILFGNGGSGWNSEIAGV
Rv3508|M.tuberculosis_H37Rv GGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFGVGGAGGVGGAGGG
Mb1485c|M.bovis_AF2122/97 QAGGAGGILWGNGGAGGSGAPG--QVGGAGGAAGLFGTGGAGGAGGAG-A
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------MNIVLGVSMAPSSIQMVVL
MMAR_0884|M.marinum_M -------------------------------MDVVLGVAIAGPIARLALV
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 MLLTFLDSLKGEVAVLSKRHRKSSKKVVVQRTVTAAGAVAATASLAFVGP
MSMEG_0204|M.smegmatis_MC2_155 ------MATKRSSRKARAKKAATLSAAAMTATALTAGVAPIAEANSAVVS
Mflv_5091|M.gilvum_PYR-GCK DGGNGGNGGLFGGNGGNGGNG----LGGGNGGNGGNAGAFA---------
Mvan_1264|M.vanbaalenii_PYR-1 SGGNGGNAGLFGGNGGNGGNG----LGSGDGGNGGDAGLFS---------
Rv3508|M.tuberculosis_H37Rv TGGAGGPGGLIWGGGGAGGVGG---AGGGTGGAGGRAELLFGAGGAGGAG
Mb1485c|M.bovis_AF2122/97 AGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVGG------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 EGEYADGATVEEDAIDVTGADD---AATASAPDRVISAILG---------
MMAR_0884|M.marinum_M GAAAEGSAVIDQSSVDLAEGPVAVLTETIVGTN-----------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 TAQAAAAAPDYKGAVTDYKNALNNYLSGTNAIGTAAGGVWN---------
MSMEG_0204|M.smegmatis_MC2_155 REVALMAGPNYTQLVNDSSNSLNNVLFAGGNFGGAAAGLWN---------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv TDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGGAGSDGGALGG
Mb1485c|M.bovis_AF2122/97 --------------------------------------------------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------LFGNGGNGGNGGVGVVGATGAVGAPGVAGAT
Mvan_1264|M.vanbaalenii_PYR-1 -------------------LFGRGGNGGNGGVGIAGATGAVGAPGVAGAT
Rv3508|M.tuberculosis_H37Rv TGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGTGGAGGDGVLGGV
Mb1485c|M.bovis_AF2122/97 -------------------TGGPGGPGGPGGPGGPGGPGGVGGTGGAGGL
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 ------------------TREGAADAGLQLSSIGVTWTDQLEAAALRDAL
MMAR_0884|M.marinum_M --------------------QLLADEGHHLVATRLCWSDQDRAEDLRRAL
TH_4162|M.thermoresistible__bu ----------------------MAARPFVTTGIALVSAGVIAAVPAFN--
MAB_1013|M.abscessus_ATCC_1997 ------------------PLAQGSGGLLPTFGTSLTHSNLTKIGDLPDVL
MSMEG_0204|M.smegmatis_MC2_155 -----------------PLAAAFPGGVLPTFYSGTGQEDLSSVDGFVDAL
Mflv_5091|M.gilvum_PYR-GCK GATGVTSGVVG-----------------GNGEDAVGYGATGAAGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GATGVTSNVTG-----------------GNGADAVGYGATGAAGAAGAAG
Rv3508|M.tuberculosis_H37Rv GGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGAG
Mb1485c|M.bovis_AF2122/97 GGTLYGAGGHGGAGGPGPIGGVGGHGGVGGAAGLLGVGGHGGAGGHGAAG
MUL_1721|M.ulcerans_Agy99 -----------------------------MSSFVIATPEFLTAAANDLSG
MAV_4827|M.avium_104 AARRIDN------------------------VMLVSAFLAAAALAQNVGG
MMAR_0884|M.marinum_M DDS---------------------------GVLDVAVLSESEAVTALLGP
TH_4162|M.thermoresistible__bu ------------------------------PAILSPQDEKLTAGDAGTAP
MAB_1013|M.abscessus_ATCC_1997 RNLASTPLPTAVPGVIPAIKIPGQGFVDLPLPTTIPGASVLNGLANALDG
MSMEG_0204|M.smegmatis_MC2_155 NALTGVFGDLN-----------------LDAVPGLPDGASTAVLAGLIPG
Mflv_5091|M.gilvum_PYR-GCK AAG-----AAGAVGSAGAAGEAGETGTWGNAGLPGKAGDAGGAGAVGAAG
Mvan_1264|M.vanbaalenii_PYR-1 AAG-----KAGAVGSAGTAGSAGAPGVWGNAGLPGAAGAAGGAGAIGTAG
Rv3508|M.tuberculosis_H37Rv AAGADAPASTGLTGGTGFAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQG
Mb1485c|M.bovis_AF2122/97 IAG--AAGKGGIFPDGSNGGAGGDAGDGGTGGRGGWLAGAGGAGGDGGIG
MUL_1721|M.ulcerans_Agy99 IGD-----------AVRAATGAAAPSTTAIAPLAGDEVSAAVTRMFGAYA
MAV_4827|M.avium_104 AMG----YERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAA
MMAR_0884|M.marinum_M AHAG------SAVLLVGEETASLSVLGGGDAP----PTMLAAAPVEGDAT
TH_4162|M.thermoresistible__bu DHT------LTLEQLRLLALTDITLGELSDVFFQGYGGGVGPNDPYYPLP
MAB_1013|M.abscessus_ATCC_1997 VFNN-PVIGPIVNRLPPLSDIVDGLIAEQDTFTAGYNWPLLQASGLTTIT
MSMEG_0204|M.smegmatis_MC2_155 LAP--AALVFALANAPLLPVTGIEVLLSGLSGIRGVTGVPSIDELIEGLS
Mflv_5091|M.gilvum_PYR-GCK AAGTVGTAGATGGTGTGANGGAGGVGGVGGTGAAGAAGGAGGLG------
Mvan_1264|M.vanbaalenii_PYR-1 VAGAAGTAGATGGTGVGGNGGAGQAGGIGGTGAAGAAGQAGTAG------
Rv3508|M.tuberculosis_H37Rv GAGGMGGSGADNASGIGADGGAGGTGGNAGAGGAGGAAGTGGTGGVVGAA
Mb1485c|M.bovis_AF2122/97 GTGGAGGAGFSRALIVAGDN--GGDGGNGGMGGAGGAGGPGGAGG-----
MUL_1721|M.ulcerans_Agy99 QEFQTLSARMEQFYTDCVRALLTGAGAYSGAEAANASP------------
MAV_4827|M.avium_104 GQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVS-----
MMAR_0884|M.marinum_M STFDTLMAHLDDQGGAPGEVLLVGSSEHTTVIADQFRDASTMRVE-----
TH_4162|M.thermoresistible__bu EGFSIYLDGFTGLAYYLTDQFLDSVVQTGIPLLADAAEFAYNNVT-----
MAB_1013|M.abscessus_ATCC_1997 NTFVQTPSGLNIKIPAALDPLGILPDSVRILPDGTLPNVTAWVPMGAG--
MSMEG_0204|M.smegmatis_MC2_155 VTQTTYSSGFDWP-ILGGSGNTTVSNLFAQLPEQSFGDIIAAIQG-----
Mflv_5091|M.gilvum_PYR-GCK ---ETGTTGGAGGVGGQGTAG----------GTGGVGGIGGAGSTGAVGG
Mvan_1264|M.vanbaalenii_PYR-1 ---ETGVTGGVGGIGGQGTEG----------GTGGVGGVGGVGATGGAGG
Rv3508|M.tuberculosis_H37Rv GKAGIGGTGGQGGAGGAGSAGTDATATGATGGTGFSGGAGGAGGAGGNTG
Mb1485c|M.bovis_AF2122/97 ---LISLLGGQG-AGGDGGDG----------GAGGVGGDRGAGANGNQAV
MUL_1721|M.ulcerans_Agy99 --------------------------------LQTLEQDLLAGINAPSQM
MAV_4827|M.avium_104 ----------------------------------VAEEPETALARGAALA
MMAR_0884|M.marinum_M ----------------------------------VPEDPTFALARGAAMA
TH_4162|M.thermoresistible__bu -------------------------------------SYFYELGVWEAFR
MAB_1013|M.abscessus_ATCC_1997 ------------------------NYTFPLGMETGWWATAPTLIVDGGAV
MSMEG_0204|M.smegmatis_MC2_155 -------------------------------EVDVPNNALTKLFVAGLFA
Mflv_5091|M.gilvum_PYR-GCK VGGKGIQGGQGLQGGKGGDGGAGGKGGD-ADSMGSAGATGGKGGNGGNGG
Mvan_1264|M.vanbaalenii_PYR-1 VGGKGIQGGQGLQGGQGGDGGTGGTGGD-ATSMGEAGATGGKGGNGGNGG
Rv3508|M.tuberculosis_H37Rv VGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGAGG
Mb1485c|M.bovis_AF2122/97 NAGAGGAGGHGGDPGAGGAGGTGGAGST-IGAHGAAGASPTSGGNGGAGG
MUL_1721|M.ulcerans_Agy99 LTGRPLIGN-----GANGVDGTGAAGGD-------GGWLVGNGGNGGSGA
MAV_4827|M.avium_104 AANAPLFASSTAALAYAQDPGTGAVDQY------SLPDYLYVPVDPEPGD
MMAR_0884|M.marinum_M AAGAGSTMAQQVLGGDAGEATT------------YLPPELAATASGQDED
TH_4162|M.thermoresistible__bu VAASELTGGPEGPVGIAL----------------GVAEFVAKNWVYLAGA
MAB_1013|M.abscessus_ATCC_1997 NVPQTVLSIPMWANGIKAPLGLGQAGQFNAHVLIPTQNGIYSPIGTTLSN
MSMEG_0204|M.smegmatis_MC2_155 TANAALGGVETPSVTAWLPSGSGNYSLLG-------GSYGWLAAMPTLVV
Mflv_5091|M.gilvum_PYR-GCK RGGLFGKGGNAG-NGADGGTG-GAGGAGGTG--------GTGGAGGTGG-
Mvan_1264|M.vanbaalenii_PYR-1 RGSLFGRGGNAG-NGGNGGTG-GNGGNGGTG--------GTGGNGGTGG-
Rv3508|M.tuberculosis_H37Rv QGGSSGAGGTNG-SGGAGGTG-GQGGAGGAGGAGADNPTGIGGAGGTGG-
Mb1485c|M.bovis_AF2122/97 NGAHFSSGGKAGGNGGAGGAG-GLVGNGGAG--------GAGGNGAPGAP
MUL_1721|M.ulcerans_Agy99 PG-------QAG---GAGGSA-GLWGAGGAG--------GAGGSATTPG-
MAV_4827|M.avium_104 DELAYSAVGEEDAESPTVVIE-KLFLPEDSE--------PRRRPVLLVG-
MMAR_0884|M.marinum_M EQLAYSQAGENELLPVTGADEYGDYGPDDDEFADDYEDEAPAGTRLSSRS
TH_4162|M.thermoresistible__bu ALTEVTSLAPLIGPDLSYATSIFFFGAEQIR--------PIGDEQYVVR-
MAB_1013|M.abscessus_ATCC_1997 FSIPVLGLGMTNLNVTTGNYLGTNGFNVNNGQNVMVLQTPFSGALPVPLV
MSMEG_0204|M.smegmatis_MC2_155 GPVDLGPIGESGTETVVAIPIFAQGLTLPMG---------LASMAMVTSP
Mflv_5091|M.gilvum_PYR-GCK -TGG--TGGIGGAG---STGGTG---------GTGGTGGTGGTGGTG---
Mvan_1264|M.vanbaalenii_PYR-1 -TGG--TGGIGGAG---STGGTG---------GTGGTGGTGGTGGTG---
Rv3508|M.tuberculosis_H37Rv -TGG--AAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGAG
Mb1485c|M.bovis_AF2122/97 PSGGDPNGGGGGAGGAGGKGGDGG-----AQAGDGGAGGAGGKGGNG---
MUL_1721|M.ulcerans_Agy99 --------GAGGAG------------------GTGGANGLIG-GGNG---
MAV_4827|M.avium_104 -------SGLAVVG-------------------ISAVLALEIALAIG---
MMAR_0884|M.marinum_M LLISNAVVAFAVIG----------------FASLAVAVAVAIRPTAS---
TH_4162|M.thermoresistible__bu ------EYTPGAVG----------------------VVNYIVDRILG---
MAB_1013|M.abscessus_ATCC_1997 YSLGGFNFGTEGAG-----------FTLPSLFGVGLMPSFQLGTAPG---
MSMEG_0204|M.smegmatis_MC2_155 GALFPTATGVSTLG--------------------GTTVQSFGIPLLG---
* .
Mflv_5091|M.gilvum_PYR-GCK -----------------GTGGTGGTG----GTGGKGGTGGTGGAGGTGGD
Mvan_1264|M.vanbaalenii_PYR-1 -----------------GTGGTGGTG----GTGGKGGTGGTGGDGGTGGT
Rv3508|M.tuberculosis_H37Rv AAAAAGSSATGGAGFAGGAGGEGGAG----GNSGVGGTNGSGGAGGAGGK
Mb1485c|M.bovis_AF2122/97 -----------------GNGATGATGLNGLGAGADGTDGGKGGNGGAGGG
MUL_1721|M.ulcerans_Agy99 -----------------GVGGAGGAG----AAGGAGAVGSTAQAGGTGGD
MAV_4827|M.avium_104 ------------------IRTTGTVALQPTPNQHLIVPTEQAPAPPPVQA
MMAR_0884|M.marinum_M -----------------SEPVEGHQNAQPGKFMPLLPTQQQAPVPPPPPD
TH_4162|M.thermoresistible__bu -----------------------------QAEPWYEPPQDPDPEPDPDPE
MAB_1013|M.abscessus_ATCC_1997 -----------------ANTPLGVIPPNLIPTGAVVPTQLITVSGLISTA
MSMEG_0204|M.smegmatis_MC2_155 ----------------IDFSVTNLLQSTYVGTNGFNVNSGTTIAALTTPF
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGG-----------TGGTGGTGGTGGTGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGG-----------TGGTGGTGGTGGTGGAG--------------
Rv3508|M.tuberculosis_H37Rv GGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGGAGGATGTGGTGGVVGA
Mb1485c|M.bovis_AF2122/97 GGAGGQGG----KALAATHQDGSMGAGGAGGNGGAG--------------
MUL_1721|M.ulcerans_Agy99 GGAGGANR----------QLVSLFGAGGAGGADGAG--------------
MAV_4827|M.avium_104 SAPQPKIS----------VPEPVAAPKPLSPPVAAP--------------
MMAR_0884|M.marinum_M APTAGFQG-------GTIPTVQGVVPRQATPTVPAP--------------
TH_4162|M.thermoresistible__bu ETENGDGD----------------GADGLTSLLGSN--------------
MAB_1013|M.abscessus_ATCC_1997 LGIPDPTVELAKALTPLYKGLVTPALTPISDLLTQQYG------------
MSMEG_0204|M.smegmatis_MC2_155 GTLPIVFS----------LGGLNAGSTGFGFTLPSLFT------------
Mflv_5091|M.gilvum_PYR-GCK ---DGTGGTGGTGGTGGQ-------------GGQGGQGGTGGTGGQGGLG
Mvan_1264|M.vanbaalenii_PYR-1 ---DGLGGTGGTGGTGGF-------------GGQGGQGGTGGTGGQGGLG
Rv3508|M.tuberculosis_H37Rv TGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGIN
Mb1485c|M.bovis_AF2122/97 ----GMGGDGGNGAKGTFDNGGDG------VGGNGGNGGSRGIGGAGGIG
MUL_1721|M.ulcerans_Agy99 ----GLGGNGGD------------------------ATGFGMTGGDGAMG
MAV_4827|M.avium_104 -----LPAAPPPAAPPLPEAPPIP--------AAPPVVPVPVVVPPVPVP
MMAR_0884|M.marinum_M -----VAPAPAPAPGVVPAPIPLP--------IPIIIPPWPNWSPGMPTP
TH_4162|M.thermoresistible__bu ------------------------------------AGSSALSSRFVTLD
MAB_1013|M.abscessus_ATCC_1997 ---NLFNGAASNTLQASKFYKDVMTQLGGLIGAAPLSSPVPKALAAADIQ
MSMEG_0204|M.smegmatis_MC2_155 -----VGVAPSFQVGTAPN-------------QQSPDGVIPASVLNLGLE
Mflv_5091|M.gilvum_PYR-GCK GGGGTGGQGGTGG-------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GVGGTGGTGGTGG-------------------------------------
Rv3508|M.tuberculosis_H37Rv GAGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTA
Mb1485c|M.bovis_AF2122/97 GAGSTAGADGARG-------------------------------------
MUL_1721|M.ulcerans_Agy99 GAVTVPVN------------------------------------------
MAV_4827|M.avium_104 VPVRIPVPDPVSPP------------------------------------
MMAR_0884|M.marinum_M STVTVTPTTPTTTAP-----------------------------------
TH_4162|M.thermoresistible__bu VAPNQKVEEADDAE------------------------------------
MAB_1013|M.abscessus_ATCC_1997 APAAEHVAAPAPAAKEP---------------------------------
MSMEG_0204|M.smegmatis_MC2_155 LPTQTTDVASLLGLP-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------TGGQGGTGGTGGTGGTG------GTGGAGGDGGLGGLG------
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGQGGTGGTGGTGGTG------GTGGAGGDGGLGGLG------
Rv3508|M.tuberculosis_H37Rv KAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTS
Mb1485c|M.bovis_AF2122/97 -----ATPTSGGNGGTGGNGANATVAG--GAGGAGGKGGNGGLV------
MUL_1721|M.ulcerans_Agy99 ------FLAHAGSDGGIGTGGNG------GLGGNGGAGGHGGIN------
MAV_4827|M.avium_104 -----QLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQ------
MMAR_0884|M.marinum_M -----STVTPTTPTTTAPSTVTPTTPTTTAPSTLTPTTPTTTVP------
TH_4162|M.thermoresistible__bu --------KPGNVEDTKDTEDAEDTEDTESTLDEDGKTG-----------
MAB_1013|M.abscessus_ATCC_1997 -----TGPAAPEVKQLEAPKPDITSNLVATKERIVEKVTSTTLS------
MSMEG_0204|M.smegmatis_MC2_155 -------DVGGAVSNVLTPVFNVTIAPIGETFTEALNEQAGPLVN-----
Mflv_5091|M.gilvum_PYR-GCK -----GFGGSGGTGGQGGLGGPG---------GSTGGAGGAGGQAGTAGK
Mvan_1264|M.vanbaalenii_PYR-1 -----GFGGVGGTGGQGGQGGPG---------GSTGGAGGAGGQAGVAGK
Rv3508|M.tuberculosis_H37Rv INANGGAGGNGGTGGKGGAGGAGTL-----GVGGSGGTGGDGGDAGSGGG
Mb1485c|M.bovis_AF2122/97 -----GNGGAGGKGGDGMAGVAGSSPTTAGESGTSGQNGGAGGAGGAGGR
MUL_1721|M.ulcerans_Agy99 ------------TGTRG----------------TASASGGTGGNGGAGGN
MAV_4827|M.avium_104 ------HQTPPGEGTPPKPDGPG---------NYGGGHVPTPGAGGSGGS
MMAR_0884|M.marinum_M -----STVITPTTTAPITPTTVAP--------TTVNPTTVAPTTVAPTTQ
TH_4162|M.thermoresistible__bu -----------------------------------ELETETPAEKVTDGT
MAB_1013|M.abscessus_ATCC_1997 --------VSAPTVPEQSVVSVGETATSPAAEPVKNVAKEAPKAEVKDAK
MSMEG_0204|M.smegmatis_MC2_155 --------DFVSTVEQLTAAIADLS--------EQLPEAGTPPAVEQEQN
Mflv_5091|M.gilvum_PYR-GCK GGLFGGS----------------------------------------GSA
Mvan_1264|M.vanbaalenii_PYR-1 GGLFGGS----------------------------------------GSA
Rv3508|M.tuberculosis_H37Rv GGFGGAAGKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSA
Mb1485c|M.bovis_AF2122/97 GGDFGGDG---------------------------------------GTG
MUL_1721|M.ulcerans_Agy99 GG------------------------------------------------
MAV_4827|M.avium_104 GG------------------------------------------------
MMAR_0884|M.marinum_M QTVVPQP-------------------------------------------
TH_4162|M.thermoresistible__bu GS------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 EADKPAKP------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 NMLAAKTG------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKAGATGAAGASG--GKGAQGAT-GAQGATGAQGATGATGAAGKAGATG-
Mvan_1264|M.vanbaalenii_PYR-1 GTAGVTGASGASG--GKGAQGAT-GAQGATGAQGATGATGASGAQGSAG-
Rv3508|M.tuberculosis_H37Rv GAGGINGAGGAGGNGGDGGDGAT-GAAGLGDNGGVGGDGGAGGAAGNGGN
Mb1485c|M.bovis_AF2122/97 GAGGNGADGGAGGNGANGANATTPGAKGGDGGHGGPGAQGGNGGQGGPGG
MUL_1721|M.ulcerans_Agy99 ----------------------------------APGAANAIGGQGGQG-
MAV_4827|M.avium_104 ---------------------------------GHVPTPGAGGSGGSGG-
MMAR_0884|M.marinum_M -------------------------------TQETVAPLPTQQTVAPQP-
TH_4162|M.thermoresistible__bu ----------------------------------ETPAGDGAAAEGSSG-
MAB_1013|M.abscessus_ATCC_1997 --------------------------VVKEKLQDKVDKATQALKDSATG-
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------DPAPPKIEGTEAKSSEG-
.
Mflv_5091|M.gilvum_PYR-GCK -------AAGAAGAAGSAGTTGAQGSAGTN--------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------SAGSAGVAGSAGTTGAQGSAGTN--------------------
Rv3508|M.tuberculosis_H37Rv AGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGL
Mb1485c|M.bovis_AF2122/97 LAGNLFGQNGIQGVGGSGGKGGAGGLAGDGGNGANGNFAFGDGNGGHGG-
MUL_1721|M.ulcerans_Agy99 ------------GIGGNGGNGGNGGTASSS--------------------
MAV_4827|M.avium_104 ------------GHVPTPGTGGPGGTGGSG--------------------
MMAR_0884|M.marinum_M ------------TIAPQPTQQAPEPPSGGS--------------------
TH_4162|M.thermoresistible__bu -------------LKQKPSDKIKPRLNVKR--------------------
MAB_1013|M.abscessus_ATCC_1997 ------------SIKQTRGAITSTITNTAES-------------------
MSMEG_0204|M.smegmatis_MC2_155 ------------GVTEVAANTEETQAVLETG-------------------
Mflv_5091|M.gilvum_PYR-GCK --------------GANGANGSQGAAGKAG-ATGTTGATG----AAGEDG
Mvan_1264|M.vanbaalenii_PYR-1 --------------GANGANGSQGAAGKAG-ATGTTGATG----AAGDAG
Rv3508|M.tuberculosis_H37Rv GGASTTSINANGGAGGNGGTGGKGGAGGAG-TLGVGGSGG----TGGDGG
Mb1485c|M.bovis_AF2122/97 -------------NGGNPGAGGQGGSGGAGSTPGAKGAHGFTPTSGGDGG
MUL_1721|M.ulcerans_Agy99 ---------------------------NTGPTPSAG--------------
MAV_4827|M.avium_104 --------------------GGHVPTPGAGTPGGSGGGHLP---------
MMAR_0884|M.marinum_M ----------------------SGGSSGGGSSSGGGSSS-----------
TH_4162|M.thermoresistible__bu -------------------------FNGPGRAAGGESTESR---------
MAB_1013|M.abscessus_ATCC_1997 ---------------------ATSAVTGGGTSAAAAEGTK----------
MSMEG_0204|M.smegmatis_MC2_155 -----------------------AKKPDDSTKASAKKMR-----------
. .
Mflv_5091|M.gilvum_PYR-GCK DAGSGGSG------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 DPGSEAVD------------------------------------------
Rv3508|M.tuberculosis_H37Rv DAGSGGGGGFGGAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQ
Mb1485c|M.bovis_AF2122/97 DGGNGGHS------------------------------------------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------IN--GGAGGAGGAGGE-----------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------IN--GGAGGAGGAGGE-----------------------
Rv3508|M.tuberculosis_H37Rv GGAGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGD
Mb1485c|M.bovis_AF2122/97 ---------QVVGGNGGDGGNGGNGGS-----------------------
MUL_1721|M.ulcerans_Agy99 ---------------TGGGGTGGGGGG-----------------------
MAV_4827|M.avium_104 -------------FPGAGSTPGGSGGG-----------------------
MMAR_0884|M.marinum_M ---------------GGGSSSGGGSSS-----------------------
TH_4162|M.thermoresistible__bu ---------------TGGKHRAEDRAE-----------------------
MAB_1013|M.abscessus_ATCC_1997 ----------------DAKAKDSDSGK-----------------------
MSMEG_0204|M.smegmatis_MC2_155 ----------------QGTQQAVKKAQ-----------------------
.
Mflv_5091|M.gilvum_PYR-GCK --------------------------------GGEGGDGGKGGAGAEG--
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------GGEGGAGGAGGDGSEG--
Rv3508|M.tuberculosis_H37Rv GGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDP
Mb1485c|M.bovis_AF2122/97 --------------------------------AGTGGNGGRGGDGAFGGM
MUL_1721|M.ulcerans_Agy99 -----------------------------------GGGGGGGGASASG--
MAV_4827|M.avium_104 ------------------------------HLPTPGAGTPGGGLGGFG--
MMAR_0884|M.marinum_M -----------------------------------GGGSSSGGGSSSG--
TH_4162|M.thermoresistible__bu -----------------------------------DKDAASTTTASTP--
MAB_1013|M.abscessus_ATCC_1997 ----------------------------------HHEDGSAGSPNKVK--
MSMEG_0204|M.smegmatis_MC2_155 -----------------------------------DRVNKVAENGRKQ--
Mflv_5091|M.gilvum_PYR-GCK -------GAGGGGGAGG-------------SGAGGAGGAGGSGGSGGSG-
Mvan_1264|M.vanbaalenii_PYR-1 -------GAGGSGGAGG-------------SGTGGAGGAGGSGGSGGSG-
Rv3508|M.tuberculosis_H37Rv SIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGD
Mb1485c|M.bovis_AF2122/97 SANATNPGENGPNGNPG--------------GNGGAGGAGGAGLNGGNG-
MUL_1721|M.ulcerans_Agy99 -------AVGGTGGGGG---------------GGGAGAAAGTGAVGGGG-
MAV_4827|M.avium_104 ---------GGHAPAPG----------------GGLGGGGGHAPAPGGG-
MMAR_0884|M.marinum_M ---------GGSSSGGG--------------SSSGGGSSSGGGSSSGRG-
TH_4162|M.thermoresistible__bu --------TASTAEAAG---------------ASLSADADTYGKHAKKG-
MAB_1013|M.abscessus_ATCC_1997 --------VKTPSESGGK------------HRAPDASGGGSSGSNAGGGS
MSMEG_0204|M.smegmatis_MC2_155 ----------VKAVTDG---------------VKKAVKETRDAVKKAIS-
* . .
Mflv_5091|M.gilvum_PYR-GCK ----GSGGSGGAAGDSDD--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----GAGGSGGAAGDSD---------------------------------
Rv3508|M.tuberculosis_H37Rv GFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGA
Mb1485c|M.bovis_AF2122/97 ----GAGGNGGLGGFGGNGAAGANG-----VAVGAPGQPGGAGGHGGAG-
MUL_1721|M.ulcerans_Agy99 ---GGAAPPAAPVAPPEMEAREATP-------------------------
MAV_4827|M.avium_104 --LGGFGGGHSGGGLGGLGGGHK---------------------------
MMAR_0884|M.marinum_M ----SSSGGSSSGGHSSGGGS-----------------------------
TH_4162|M.thermoresistible__bu ---TGTGTGAGEGGDE----------------------------------
MAB_1013|M.abscessus_ATCC_1997 DGSGSHGGSGAGGGKHSAGD------------------------------
MSMEG_0204|M.smegmatis_MC2_155 ---KPAKKTQSTGTDNDNKDSE----------------------------
.
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv LSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGV
Mb1485c|M.bovis_AF2122/97 ----GNGGAGGNGGQGVVS--DGAGGAGGAGGDGGAPGDGANGGNGQGAG
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv ASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAG
Mb1485c|M.bovis_AF2122/97 AFAGGGGGRGGDGGNAGNAGAGGPGGTGS---------------TAGKAG
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv ADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGN
Mb1485c|M.bovis_AF2122/97 PAGSILHDGGNGGHGGHG--------------AASGGNGGPGGHGGNGGN
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGA
Mb1485c|M.bovis_AF2122/97 GGTGAN--GGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGGNGGRGGN
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQN
Mb1485c|M.bovis_AF2122/97 GGQGLTGAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDG-----------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGG
Mb1485c|M.bovis_AF2122/97 ---------GGGGRGGDAGRGGDAGLGGSSGPG-GTPGDWGTGGTGGTGG
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv AGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAG
Mb1485c|M.bovis_AF2122/97 TGGQGANG-----GLTGGRGGTGGNGGAGGTGGTGHNGSQPGMGGNGGAG
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GAGGNGGAGGLGGGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGT
Mb1485c|M.bovis_AF2122/97 GFGGNGFAG----------VGGRGGMGGSGGTGGTGDAGPFGTG-----T
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GGDGGDAGAGGNGGSATGVGNGGNGGDGGNGGDGGNGAPGGFGGGAGAGG
Mb1485c|M.bovis_AF2122/97 GGTGGHGGQGGGGGFSILLGLGGLGG-LGSPGSIATGTAGGAGGGGGFGG
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0884|M.marinum_M --------------------------------------------------
TH_4162|M.thermoresistible__bu --------------------------------------------------
MAB_1013|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0204|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------
Rv3508|M.tuberculosis_H37Rv LGGSGAGGGTDGDDGNGGSPGTDGS
Mb1485c|M.bovis_AF2122/97 LGGGEFV------------------
MUL_1721|M.ulcerans_Agy99 -------------------------
MAV_4827|M.avium_104 -------------------------
MMAR_0884|M.marinum_M -------------------------
TH_4162|M.thermoresistible__bu -------------------------
MAB_1013|M.abscessus_ATCC_1997 -------------------------
MSMEG_0204|M.smegmatis_MC2_155 -------------------------