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VLAAAIQLEAVIGDVAANLGKCAQLAAEAGRAGAKIIALPEFFTTGIAFDPALRDAALPPEGAATELLRT LAHHYDALVGGSFLCRDKDGHVRNAYFAADATGMVGRHDKDLPTMWENAFYIGGQDDGVFRAGTLNVGAA VCWELMRTRTARRMRAHVDLVMAGSGWWSIPPWRPRATFAAMERRNHQTARAAAATFAKYVGAPVVHAAH VGEFHCAMPWIPLKYRGHFEGSTLITDGTGSIVAERRPEEGPGIVLGDIHLGRLPPAAEVPDRFWLHSRG ALPTAAWHYQRWHGRRWYRRNMVTT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0482c | - | - | 100% (306) | hypothetical protein MAB_0482c |
| M. abscessus ATCC 19977 | MAB_0819 | - | 7e-08 | 23.66% (262) | carbon-nitrogen hydrolase family protein |
| M. abscessus ATCC 19977 | MAB_2818c | - | 2e-06 | 25.00% (272) | putative hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0490c | - | 1e-05 | 24.07% (270) | hypothetical protein Mb0490c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0480c | - | 1e-05 | 24.07% (270) | amidohydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0805 | - | 2e-05 | 26.02% (269) | amidohydrolase |
| M. avium 104 | MAV_4670 | - | 6e-08 | 24.71% (263) | carbon-nitrogen hydrolase |
| M. smegmatis MC2 155 | MSMEG_6733 | - | 4e-08 | 32.93% (167) | hydrolase, carbon-nitrogen family protein |
| M. thermoresistible (build 8) | TH_2485 | - | 1e-135 | 74.26% (303) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4548 | - | 5e-06 | 26.39% (269) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_0813 | - | 0.0001 | 24.66% (219) | Nitrilase/cyanide hydratase and apolipoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0490c|M.bovis_AF2122/97 MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSGTDPAANLQ
Rv0480c|M.tuberculosis_H37Rv -------------------------------MRIALAQIRSGTDPAANLQ
MAV_4670|M.avium_104 -------------------------------MRIALAQILSGTDPAANLA
MMAR_0805|M.marinum_M -------------------------------MRIALAQILSGTDPTANLE
MUL_4548|M.ulcerans_Agy99 -------------------------------MRIALAQILSGTDPTANLE
Mvan_0813|M.vanbaalenii_PYR-1 -------------------------------MRIALAQIRGSTDPAENLD
MAB_0482c|M.abscessus_ATCC_199 -----------------------------MVLAAAIQLEAVIGDVAANLG
TH_2485|M.thermoresistible__bu -----------------------------MVLAAAIQLEAVLGDVAANLA
MSMEG_6733|M.smegmatis_MC2_155 ---------------------------MRTVDVAVVQEPAVAGDVAANVR
.: * : *:
Mb0490c|M.bovis_AF2122/97 LVGKYAGEAATAGAQLVVFPEATMC--RLGVPLRQVAEPVDGP-WANGVR
Rv0480c|M.tuberculosis_H37Rv LVGKYAGEAATAGAQLVVFPEATMC--RLGVPLRQVAEPVDGP-WANGVR
MAV_4670|M.avium_104 LVGEYTRRAAGAGARLVVFPEATMC--RFGVPLAPIAEPVDGP-WADGVR
MMAR_0805|M.marinum_M LVRDYAERAADAGARLVVFPEATMC--RFGVPLGPVAQPLDGP-WANGVR
MUL_4548|M.ulcerans_Agy99 LVRDYAERAADAGARLVVFPEATMC--RFGVPLGPVAQPLDGP-WANGVR
Mvan_0813|M.vanbaalenii_PYR-1 LVEEYTGRAAEAGASLVLFPEATIC--RFGVPPAEIAEPFDGP-WASAVR
MAB_0482c|M.abscessus_ATCC_199 KCAQLAAEAGRAGAKIIALPEFFTTGIAFDPALRDAALPPEGA-ATELLR
TH_2485|M.thermoresistible__bu TCERLADEAGRAGAKIIALPEFFTTGIGFDESLGHAVLPPDGK-ATALLT
MSMEG_6733|M.smegmatis_MC2_155 --RAVAALAKHPGADLVVFPELFLCGYRLDVVADAAIEMIPEPGPVADLC
: * .** :: :** :. . :
Mb0490c|M.bovis_AF2122/97 RIATEAGITVIAGMFTPTGDG-RVTNTLIAAGPGTPNQPDAHYHKIHLYD
Rv0480c|M.tuberculosis_H37Rv RIATEAGITVIAGMFTPTGDG-RVTNTLIAAGPGTPNQPDAHYHKIHLYD
MAV_4670|M.avium_104 RIATEANVTVIAGMFTPSGDG-RVKNTLLVAN--SDDQAVTHYDKIHLYD
MMAR_0805|M.marinum_M RIAAQTGITVVAGMFTPADAG-RVSNTLFAAGPGAPNQPDDHYHKIHLYD
MUL_4548|M.ulcerans_Agy99 RIAAQTGITVVAGMFTPADAG-RVSNTLFAAGPGAPNQPDDHYHKIHLYD
Mvan_0813|M.vanbaalenii_PYR-1 GIAARAGVVVVAGMYVPSDDDDRVTNTLIATGPGVDAR----YDKIHLYD
MAB_0482c|M.abscessus_ATCC_199 TLAHHYDALVGGSFLCRDKDG-HVRNAYFAADATGMVG-------RHDKD
TH_2485|M.thermoresistible__bu SLAKRYGALVGGSFLCRDADG-EVRNAYLAADPGGVIG-------RHDKD
MSMEG_6733|M.smegmatis_MC2_155 AAAAAHDTAVVTGFAERSGDL--VYNSLLCIDRTGAVAG--VYRKTHLFG
* . * .: * *: : . * .
Mb0490c|M.bovis_AF2122/97 AFGFTESRTVAPGREPVVVVVDG----VRVGLTVCYDIRFPALYTELARR
Rv0480c|M.tuberculosis_H37Rv AFGFTESRTVAPGREPVVVVVDG----VRVGLTVCYDIRFPALYTELARR
MAV_4670|M.avium_104 AFGFTESRTVAPGREPVVVGVDG----VRVGLSVCYDIRFPELYTELARR
MMAR_0805|M.marinum_M AFGFAESRTVAPGHEPVVITVDD----VQVGLTVCYDIRFPALYTELARR
MUL_4548|M.ulcerans_Agy99 AFGFAESRTVAPGHEPVVITVDD----FQVGLTVCYDIRFPALYTELARR
Mvan_0813|M.vanbaalenii_PYR-1 AFGFSESKTVAPGRDPVVITVESESGPVKVGLTLCYDIRFPELYVELAER
MAB_0482c|M.abscessus_ATCC_199 LPTMWENAFYIGGQDDGVFRAGT----LNVGAAVCWELMRTRTARRMRAH
TH_2485|M.thermoresistible__bu RPTMWENAFYIGGADDGVFRYGD----HHVGAAVCWELMRTPTVHRLRSR
MSMEG_6733|M.smegmatis_MC2_155 ----AECEAFATGDRLEVIEVDG----LRVGPMICFDVEFPEIARTLALS
* * *. .** :*::: . :
Mb0490c|M.bovis_AF2122/97 GAQLIAVCASWGSGPGK--------LEQWTLLARARALDSMSYVAA--AG
Rv0480c|M.tuberculosis_H37Rv GAQLIAVCASWGSGPGK--------LEQWTLLARARALDSMSYVAA--AG
MAV_4670|M.avium_104 GAQLIAVCASWGAGPGK--------LDQWTLLARARALDSMSYIAA--AG
MMAR_0805|M.marinum_M GAELIVVSASWGSGPGK--------LDQWTLLARARALDSASYVAA--AG
MUL_4548|M.ulcerans_Agy99 GAELIVVSASWGSGPGK--------LDQWTLLARARALDSASYVAA--AG
Mvan_0813|M.vanbaalenii_PYR-1 GAEIITAHASWGNGPGK--------IDQWTLLARARAIDTSTVVAA--VG
MAB_0482c|M.abscessus_ATCC_199 VDLVMAGSGWWSIPPWRPRATFAAMERRNHQTARAAAATFAKYVGAPVVH
TH_2485|M.thermoresistible__bu VDLVLTGSGWWSIPPWPPRALFERWEERNRATARAAAATFAKYVGAPVVH
MSMEG_6733|M.smegmatis_MC2_155 GVDLFVVSSANMFPYHH----------DHRVACLSRALENRTPLVYSNLI
::. . . : * . :
Mb0490c|M.bovis_AF2122/97 QADPGDARTGVGASSAAPTG--VGGSLVASPLGEVVVSAGTQ--PQLLVA
Rv0480c|M.tuberculosis_H37Rv QADPGDARTGVGASSAAPTG--VGGSLVASPLGEVVVSAGTQ--PQLLVA
MAV_4670|M.avium_104 QADPG----GSLSASGAPTG--VGGSLVASPLGEVVASAGAQ--PQLVLA
MMAR_0805|M.marinum_M QADPGDTASDPGGGSGAPRG--VGGSLVASPLGEVVASAGSD--PQLVVA
MUL_4548|M.ulcerans_Agy99 QADPGDTASDPGGGSGAPRG--VGGSLVTSPLGEVVASAGSD--PQLVVA
Mvan_0813|M.vanbaalenii_PYR-1 QAYPGD-----EIAALGPTG--VGHSVVASALGEVLASAGAD--PQLLMC
MAB_0482c|M.abscessus_ATCC_199 AAHVGEFHCAMPWIPLKYRGHFEGSTLITDGTGSIVAERRPEEGPGIVLG
TH_2485|M.thermoresistible__bu AAHAGELTCRMPWAPITYRGRFEGSTLITDADGTVIAERRPEEGQGVVLG
MSMEG_6733|M.smegmatis_MC2_155 GAEAG----------LTFVG----GSRVVDAGGELLVECGGE--VSVARC
* * * : :.. * ::.. : :
Mb0490c|M.bovis_AF2122/97 DIDVDNVAAARDRIAVLRNQTDFVQIDKAQSRG-----------------
Rv0480c|M.tuberculosis_H37Rv DIDVDNVAAARDRIAVLRNQTDFVQIDKAQSRG-----------------
MAV_4670|M.avium_104 DIDVDRVAQARKTIAALSNRSDFAQVGRAESVG-----------------
MMAR_0805|M.marinum_M DIDLAKVGAARDNIGVLRNQSRFTQTDKAQSRR-----------------
MUL_4548|M.ulcerans_Agy99 DIDLAKVGAARDNIGMLRNQSRFTQTDKAQSRR-----------------
Mvan_0813|M.vanbaalenii_PYR-1 DIDLEAARAARQTVAVMHNRSEAVRSSRERSSPAVRSSRERSSPAVRSSR
MAB_0482c|M.abscessus_ATCC_199 DIHLGRLPPAAEVPDRFWLHSRGALPTAAWHYQRWHGRRWYRRNMVTT--
TH_2485|M.thermoresistible__bu EIDLGRRPPLLDPPRRYWLHPRGPLPAAVWHYQRWHGRRWYRRHMRSARG
MSMEG_6733|M.smegmatis_MC2_155 RVTPATATSTEDDVDYLRHRRPELYRLK----------------------
: . :
Mb0490c|M.bovis_AF2122/97 -----
Rv0480c|M.tuberculosis_H37Rv -----
MAV_4670|M.avium_104 -----
MMAR_0805|M.marinum_M -----
MUL_4548|M.ulcerans_Agy99 -----
Mvan_0813|M.vanbaalenii_PYR-1 ER---
MAB_0482c|M.abscessus_ATCC_199 -----
TH_2485|M.thermoresistible__bu ASGPS
MSMEG_6733|M.smegmatis_MC2_155 -----