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SGDGWDGMSHAEIVGKLSQLKPDNAFNLAQSWSDIYSKVSDSAEQYTRAASTMERIWTGDGPDAARQSLK AKYQELQADDGIAAKAGKLQNALTQDGACLTNAGRVPQMYPVPPDNTDKDAKQKLLEAVRAEAERLYTEP LDVTRPKIDDAASDNSGSGAIQQPGGGGGSGGGGGGNSAGGGSDSKPQSPGGGTDGLADKNTKPQLANGD GQGGQGQGAGSGSGSGAGGGQGAGSGSGAGGSSPFGSGSGTGTGGSGLPLGSTTAAGYGPSGSAGGTGLA SGTAGGASALRAGGGLPGGATSGAGANPAAIGAAGVRGGAMGPMGMMGGAGAHGKGGHGEDDDEHETPAI LINLDNTYEFMGDLPKASPAVIGDWSEQEKADKQAQEREKRRYKKLGWDVEFE*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0010c | - | - | 100% (404) | hypothetical protein MAB_0010c |
M. abscessus ATCC 19977 | MAB_1830 | - | e-135 | 60.48% (415) | hypothetical protein MAB_1830 |
M. abscessus ATCC 19977 | MAB_1280c | - | 2e-77 | 42.96% (426) | hypothetical protein MAB_1280c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3543 | PE_PGRS57 | 1e-27 | 39.20% (199) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-26 | 40.00% (185) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 8e-28 | 38.89% (216) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 5e-08 | 28.65% (171) | translation initiation factor IF-2 |
M. marinum M | MMAR_0943 | - | 7e-28 | 38.49% (239) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 7e-17 | 36.63% (202) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-19 | 35.75% (221) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 3e-15 | 34.74% (190) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 2e-25 | 36.32% (234) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 9e-25 | 38.83% (188) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv -------------------------------------------------- MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0943|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -----------------------------------------MSFVLIAPE Rv3508|M.tuberculosis_H37Rv -----------------------------------------MSFVLIAPE MUL_4367|M.ulcerans_Agy99 -----------------------------------------MSFVSVGPG MMAR_0943|M.marinum_M -----------------------------------------MSFTVVEPQ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 --------------------------------------MNIVLGVSMAPS MLBr_01556|M.leprae_Br4923 ----------------------------------------MAGKARVHEL Mb3543|M.bovis_AF2122/97 FVTAAAGDLTNLGSSISAANASAASATTQVLAAG---------------- Rv3508|M.tuberculosis_H37Rv FVTAAAGDLTNLGSSISAANASAASATTQVLAAG---------------- MUL_4367|M.ulcerans_Agy99 LLEAAARDLAGLGAGLREANLAAAGATVGVLPAA---------------- MMAR_0943|M.marinum_M MLTAAAADLAKIGAAIDTVSTAAAASTTNLLPAA---------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------MMFLAPPGGPGPISAAIQLTSTG---------------- MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 SIQMVVLEGEYADGATVEEDAIDVTGADDAATAS---------------- MLBr_01556|M.leprae_Br4923 AKELGVTSKEVLARLNEQGEFVKSASSTVEAPVAR--------------- Mb3543|M.bovis_AF2122/97 ----ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS Rv3508|M.tuberculosis_H37Rv ----ADEVSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYAS MUL_4367|M.ulcerans_Agy99 ----GDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQ MMAR_0943|M.marinum_M ----ADEVSAAIASLFGTHALAYQAIGAQAATFHDGFVQALSRAASRYAA Mflv_5091|M.gilvum_PYR-GCK ------------MVTFGGGATPTPTS--------------LGAAAVDLSG Mvan_1264|M.vanbaalenii_PYR-1 ----SEATEPWYVVSFGGSGAPTPNN--------------LAASLVDLSG MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------APDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDAL MLBr_01556|M.leprae_Br4923 ----------RLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRA Mb3543|M.bovis_AF2122/97 AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT Rv3508|M.tuberculosis_H37Rv AEAA---------------AAEQIVLGVINAPTQALLGRPLIGDGAN-AT MUL_4367|M.ulcerans_Agy99 AEALNMWPLQ---------ELEQQALGVVNAPSMALFGRPSIGNGVDGVA MMAR_0943|M.marinum_M TEVAN---------------VEQNLLGLINAPTQALFGRPLIGNGADGAA Mflv_5091|M.gilvum_PYR-GCK TSCG------------------------------------LICNGQD--- Mvan_1264|M.vanbaalenii_PYR-1 TSCG------------------------------------LICNGQD--- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN-GT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 ----------------------------------------MSGDGWD--- MAV_4827|M.avium_104 AARR---------------------------IDNVMLVSAFLAAAALAQN MLBr_01556|M.leprae_Br4923 LDKAVAG----------------------------------NGATTAAPV Mb3543|M.bovis_AF2122/97 TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG Rv3508|M.tuberculosis_H37Rv TPGGAGGAGGLLFGNGGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSG MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGGVG MMAR_0943|M.marinum_M GTGQTGQAGGLLWGNGGAGG-SGAPGQSGGTGGAAGFIGSGGSGGTGGLG Mflv_5091|M.gilvum_PYR-GCK ---GTGQNGGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG Mvan_1264|M.vanbaalenii_PYR-1 ---GTGQNGGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------VDGDGGSGGRTGLFSKLSRGGDGGDG MAB_0010c|M.abscessus_ATCC_199 -----GMSHAEIVGKLSQLKPDNAFNLAQSWSDIYSKVSDSAEQYTRAAS MAV_4827|M.avium_104 VGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAG MLBr_01556|M.leprae_Br4923 QVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAP . . Mb3543|M.bovis_AF2122/97 -----GGTGGAGGAGGWLFGVGGAGGVG-----GAGGGTGGAGGPGGLIW Rv3508|M.tuberculosis_H37Rv -----GGTGGAGGAGGWLFGVGGAGGVG-----GAGGGTGGAGGPGGLIW MUL_4367|M.ulcerans_Agy99 AAGMTGGSGGAGGGGGWLWGAGGSGGAA-----GAGG----SGGSGGWLW MMAR_0943|M.marinum_M ------AAGGAGG-SAWLLGTGGTGGAGGWAAAGATGGIGGQGGAGGWLY Mflv_5091|M.gilvum_PYR-GCK -----GGNGGNGGNAGAFALFGNGGNGG-------------NGGVG---- Mvan_1264|M.vanbaalenii_PYR-1 -----SGDGGNGGDAGLFSLFGRGGNGG-------------NGGVG---- MSMEG_0868|M.smegmatis_MC2_155 ------LDGGNGGSGGLLMGIGGAGGAG------------GVGADGTSAH TH_3810|M.thermoresistible__bu -------------------GLGGNGGHG---------------------- MAB_0010c|M.abscessus_ATCC_199 ----------------TMERIWTGDGPD---------------------- MAV_4827|M.avium_104 ------------QLSAMVAGLEKLESLP---------------------- MLBr_01556|M.leprae_Br4923 ----------HPGHPGMPTGPHPGPAPK---------------------- Mb3543|M.bovis_AF2122/97 GGGG------AGGVGGAGGG--------TGGAGGRAELLFGAGGAGGAGG Rv3508|M.tuberculosis_H37Rv GGGG------AGGVGGAGGG--------TGGAGGRAELLFGAGGAG---G MUL_4367|M.ulcerans_Agy99 GNAGQTA---GAGVGGAGG---------AGGAGDAGDQGVSGVAPG---E MMAR_0943|M.marinum_M GNGGIGGQGGAGALGGAGGSGGAARLFGIGGAGGAGGHGVAGTAGTTASS Mflv_5091|M.gilvum_PYR-GCK ---------VVGATGAVGAP---------GVAGATGATGVTSGVVG---- Mvan_1264|M.vanbaalenii_PYR-1 ---------IAGATGAVGAP---------GVAGATGATGVTSNVTG---- MSMEG_0868|M.smegmatis_MC2_155 VDGG------TGGTGGTGGG--------TGGTGGIG--GTGGGLFG---L TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -----------GGLLLVGSG---------------VDVAPLKQVLQTTTF MLBr_01556|M.leprae_Br4923 ---------PGGRPPRVGNN--------PFSSAQSVARPIPRPPAPRPSA Mb3543|M.bovis_AF2122/97 AGTDGGPGATGGTGGHGGVGGDG----GWLAPGGAGGAGGQGGAGGAGSD Rv3508|M.tuberculosis_H37Rv AGTDGGPGATGGTGGHGGVGGDG----GWLAPGGAGGAGGQGGAGGAGSD MUL_4367|M.ulcerans_Agy99 AGAVGFAGGAGGAGGAGGNGVGG----GVNGAGGAGGAGGVGGGGGAGAS MMAR_0943|M.marinum_M AGVSGTDGGAGGIGGDGGAGGAGGLLIGNGGAGGAGGLGGLGGVGGAGAT Mflv_5091|M.gilvum_PYR-GCK -GNGEDAVGYGATGAAGAAGAAG-------AAGAAGAVGSAGAAGEAGET Mvan_1264|M.vanbaalenii_PYR-1 -GNGADAVGYGATGAAGAAGAAG-------AAGKAGAVGSAGTAGSAGAP MSMEG_0868|M.smegmatis_MC2_155 LGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGSETRGGTGGAGGT TH_3810|M.thermoresistible__bu ----------GGTGIISLLSLAG-----------------NGGNGGNGYR MAB_0010c|M.abscessus_ATCC_199 -----AARQSLKAKYQELQADDG----------------IAAKAGKLQNA MAV_4827|M.avium_104 LDVSVAEEPETALARGAALAAAN-------APLFASSTAALAYAQDPGTG MLBr_01556|M.leprae_Br4923 SPSSMSPRPGGAVGGGGPRPPRTG----VPRPGGGRPGAPVGGRSDAGGG . Mb3543|M.bovis_AF2122/97 GGALG------GTGGTGGTGGAGGAGGRGAL-----------LLGAGGQG Rv3508|M.tuberculosis_H37Rv GGALG------GTGGTGGTGGAGGAGGRGAL-----------LLGAGGQG MUL_4367|M.ulcerans_Agy99 GVGAG------VAGGDGGTGGAGGAAGVG---------------GAAGTG MMAR_0943|M.marinum_M GADAANPTTTGQAGGDGGNGGAGGAGGDGGGGGKSGWLGLAGALGGGGTG Mflv_5091|M.gilvum_PYR-GCK GTWGN-------AGLPGKAGDAGGAGAVG----------------AAGAA Mvan_1264|M.vanbaalenii_PYR-1 GVWGN-------AGLPGAAGAAGGAGAIG----------------TAGVA MSMEG_0868|M.smegmatis_MC2_155 GGQST-------AAGPGKGGGGGGGGGGAIL--------------IGANG TH_3810|M.thermoresistible__bu TTDNN--------ALDGGHGGNGG------------------------NV MAB_0010c|M.abscessus_ATCC_199 LTQDG--------ACLTNAGRVPQMYPVP----------------PDNTD MAV_4827|M.avium_104 AVDQYSLPDYLYVPVDPEPGDDELAYSAVGE--------------EDAES MLBr_01556|M.leprae_Br4923 NYRGG------GVGALPGGGSGGFRGRPGG----------------GGHG * Mb3543|M.bovis_AF2122/97 GLGGAGGQGGMGGAGGAGADNP----------TGIGGTGGDGGTGG---- Rv3508|M.tuberculosis_H37Rv GLGGAGGQGGTGGAGGDGVLG------------GVGGTGGKGGVGG---- MUL_4367|M.ulcerans_Agy99 GTGGAAGVAGTGGDGGD------------------GGAGGAGSDAS---- MMAR_0943|M.marinum_M GSGGAGGAAGDGGDGATGVSGGDGSSGGNGGNPGVGGAGGAGGTGAGGAR Mflv_5091|M.gilvum_PYR-GCK GTVGTAGATGGTGTGAN------------------GGAGGVGGVGG---- Mvan_1264|M.vanbaalenii_PYR-1 GAAGTAGATGGTGVGGN------------------GGAGQAGGIGG---- MSMEG_0868|M.smegmatis_MC2_155 GTVDGHAIGGNGGNGGNGSTT------------AAGGNGGTGGTGR---- TH_3810|M.thermoresistible__bu GFFSLFNLGGAGGWGGS-------------------GVDGVDVVGG---- MAB_0010c|M.abscessus_ATCC_199 KDAKQKLLEAVRAEAER------------------LYTEPLDVTRP---- MAV_4827|M.avium_104 PTVVIEKLFLPEDSEPR--------------------RRPVLLVGS---- MLBr_01556|M.leprae_Br4923 GGGRPGQRGGAAGAFGR-----------------PGGAPRRGRKSKRQ-- Mb3543|M.bovis_AF2122/97 -----------SAGEGGAGGA------AGQLFSASGAAGNAGVGGAGGQG Rv3508|M.tuberculosis_H37Rv -----------VAGLGGAGGA------AGQLFSAGGAAGAVGVGGTGGQG MUL_4367|M.ulcerans_Agy99 -----------LAGQAGFAGG------SGGAGGVGGSAGAGGVNGSGGDG MMAR_0943|M.marinum_M AADGATGNSPTSGGNGGNGGAGADAIGSGQSGGAGGAGGNGGRVGNGGNG Mflv_5091|M.gilvum_PYR-GCK ---------------------------TGAAGAAGGAGGLGETGTTGGAG Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------TGAAGAAGQAGTAGETGVTGGVG MSMEG_0868|M.smegmatis_MC2_155 ---------VIAEGTGSTAEG-------TATGGDGGHSTGTGIGGNGGIG TH_3810|M.thermoresistible__bu -------------------------------NPDGGTPGAHGESHTPGVY MAB_0010c|M.abscessus_ATCC_199 ----------------------------KIDDAASDNSGSGAIQQPGGGG MAV_4827|M.avium_104 ----------------------------GLAVVGISAVLALEIALAIGIR MLBr_01556|M.leprae_Br4923 ---------------------------KRQEYDSMQAPVVGGVRLPHGNG * Mb3543|M.bovis_AF2122/97 GDGGAGGAGADADQ--PGATGGTGFAGGAGGA----------GGAGGSSG Rv3508|M.tuberculosis_H37Rv GAGGAGAAGADAPAS-TGLTGGTGFAGGAGGV----------GGQGGNAI MUL_4367|M.ulcerans_Agy99 GAGAAGGAGG-ASAT-VAGSGGVGGDGGAG------------GAAGGGVG MMAR_0943|M.marinum_M GAGGNGFLGAPAFSSNPGGNGGNGGAGGAGGNGGIQAGNGGDGGAGGHGG Mflv_5091|M.gilvum_PYR-GCK GVGGQGTAGG---------TGGVGGIGGAGST----------GAVGGVGG Mvan_1264|M.vanbaalenii_PYR-1 GIGGQGTEGG---------TGGVGGVGGVGAT----------GGAGGVGG MSMEG_0868|M.smegmatis_MC2_155 SVYAYGNNGAVSGTA-TGGRGGDGIDGGTGGAGGMGEIYSGADGEATGIS TH_3810|M.thermoresistible__bu TD-----------------RQGEDGEDGTG-------------------- MAB_0010c|M.abscessus_ATCC_199 GSGGGG--------------GGNSAGGGSDSK------------------ MAV_4827|M.avium_104 TTGTVALQPTPNQHLIVPTEQAPAPPPVQASAP----------------- MLBr_01556|M.leprae_Br4923 ETIRLARGASLSDFAEKIDANPAALVQALFNLG----------------- Mb3543|M.bovis_AF2122/97 AGGTNGS-------------GGAGGTGGQGGM----GGAGGAGADNPTGI Rv3508|M.tuberculosis_H37Rv AGGINGS-------------GGAGGTGGQGGA----GGMGGSGADNASGI MUL_4367|M.ulcerans_Agy99 AASLGGD-------------GGHAGAGGAGGE----GLSGGFNTGAAGGI MMAR_0943|M.marinum_M AGATGGSGTNGFDGAFSGADGSPGGNGGKGGT----GGAGGNGGAAGLAL Mflv_5091|M.gilvum_PYR-GCK KGIQGGQ-------------GLQGGKGGDGGA----GGKGG----DADSM Mvan_1264|M.vanbaalenii_PYR-1 KGIQGGQ-------------GLQGGQGGDGGT----GGTGG----DATSM MSMEG_0868|M.smegmatis_MC2_155 AGGDGGS------------ATGADSLGGRGGTSWVQAGYGPTTGGKASGT TH_3810|M.thermoresistible__bu --------------------TGIGGRGGNGGS--------------SSGT MAB_0010c|M.abscessus_ATCC_199 ---------------------PQSPGGGTDGL-------------ADKNT MAV_4827|M.avium_104 --------------------QPKISVPEPVAAPKPLSPPVAAPLPAAPPP MLBr_01556|M.leprae_Br4923 --------------------EMVTATQSVGDET--LELLGSEMNYNVQVV Mb3543|M.bovis_AF2122/97 GGTGGDG--GTGGAAGAGGAGGAAGTGGTGGM------IGTTGNAG-VGG Rv3508|M.tuberculosis_H37Rv GADGGAG--GTGGNAGAGGAGGAAGTGGTGGV------VGAAGKAG-IGG MUL_4367|M.ulcerans_Agy99 GGAGGAG--GTGGDS--GGVGGVNGDGGAGGG------GGRGGDGGSSTS MMAR_0943|M.marinum_M AATGHDGGHGTGGAGGNGGAGGSAGNGGNGAKGVSGVNNGAGGNGG-DGG Mflv_5091|M.gilvum_PYR-GCK GSAGATG--GKGGNGGNGGRGGLFGKGGNAGN---------GADGG-TGG Mvan_1264|M.vanbaalenii_PYR-1 GEAGATG--GKGGNGGNGGRGSLFGRGGNAGN---------GGNGG-TGG MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATG---NTAIGGNGGAASA TH_3810|M.thermoresistible__bu HPMAEDG-----------------------------------------EH MAB_0010c|M.abscessus_ATCC_199 KPQLANG-----------------------------------------DG MAV_4827|M.avium_104 AAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPP MLBr_01556|M.leprae_Br4923 SPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDT Mb3543|M.bovis_AF2122/97 AGGQGGDGGAGGA--GADADQPGATGGTGFAGGAGGAGGAG--------- Rv3508|M.tuberculosis_H37Rv TGGQGGAGGAGSA--GTDATATGATGGTGFSGGAGGAGGAGGNTGVGGTN MUL_4367|M.ulcerans_Agy99 TSGVGGAGGAGGN--GGNAGFGVSAGGTGGSAGDGGAGGGAG-------- MMAR_0943|M.marinum_M TPGIGGTGGAGGDSGGGSHGATGSDGATPHSGGNGGKGGDGADATG---- Mflv_5091|M.gilvum_PYR-GCK AGGAGGTGGTGGA------------GGTGGTGGTGGIGGAG--------- Mvan_1264|M.vanbaalenii_PYR-1 NGGNGGTGGTGGN------------GGTGGTGGTGGIGGAG--------- MSMEG_0868|M.smegmatis_MC2_155 NGAVGGNGGFTNI--------AAIHGSITDSSATSGHGGAAQ-------- TH_3810|M.thermoresistible__bu VKALDGRPGLDGG-----------------NGSHGGN------------- MAB_0010c|M.abscessus_ATCC_199 QGGQGQGAGSGSG-----------------SGAGGGQG------------ MAV_4827|M.avium_104 RLSVPQPVQPPVR-----------VPQPPSPPQVGGTVPQSP-------- MLBr_01556|M.leprae_Br4923 IRKANVREAEAGG-----------ITQHIGAYQVGVDLDGSE-------- . Mb3543|M.bovis_AF2122/97 -----------------------------------------------GSS Rv3508|M.tuberculosis_H37Rv GSGGQGGTGGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGAGGQGGSS MUL_4367|M.ulcerans_Agy99 -----------------------------------------------GVD MMAR_0943|M.marinum_M ---------------------------------------------FGQTG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------G TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------P MLBr_01556|M.leprae_Br4923 -----------------------------------------------RLI Mb3543|M.bovis_AF2122/97 GAGGTNGSGGAGGTGGQGGAGGAGGAGADNPT----GIGGTGGD-GGTGG Rv3508|M.tuberculosis_H37Rv GAGGTNGSGGAGGTGGQGGAGGAGGAGADNPT----GIGGAGGT-GGTGG MUL_4367|M.ulcerans_Agy99 GVGGASGNGGAAGAGGAGGSG--IGAGIDG------GAGGAGGT-GGAAG MMAR_0943|M.marinum_M GNGGRGGNGGLVGNGGDGGTGGAGGTGLGGLTNSFPGSSGTGGDPGGTGG Mflv_5091|M.gilvum_PYR-GCK STGGTGGTGGTGGTGGTGGTG---------------GTGGTGGT-GGTGG Mvan_1264|M.vanbaalenii_PYR-1 STGGTGGTGGTGGTGGTGGTG---------------GTGGTGGT-GGTGG MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNG--GDGGFNGTGGATGG TH_3810|M.thermoresistible__bu --GGHGGRGGFLGIGGSGGWG---------------GHGGNGGD------ MAB_0010c|M.abscessus_ATCC_199 -AGSGSGAGGSSPFGSGSGTG----------------TGGSGLP------ MAV_4827|M.avium_104 QHQTPPGEGTPPKPDGPGNYG-----------------GGHVPT------ MLBr_01556|M.leprae_Br4923 TFIDTPGHEAFTAMRARGAKAT------DIAILVVAADDGVMPQTVEAIN * . . .* Mb3543|M.bovis_AF2122/97 AAGAGGAGGAAG-TGGTG-GMIGTTGNAGVGGAGGQGGDGGAG------- Rv3508|M.tuberculosis_H37Rv AAGAGGAGGAIG-TGGTG-GAVGSVGNAGIGGTGGTGGVGGAGGAGAAAA MUL_4367|M.ulcerans_Agy99 FPGGGGTTGAWG-TGGAG-GAGGAGGAGDHGGVGVNPGDSGTAG------ MMAR_0943|M.marinum_M NGGAGGSGGFFAGDGGNG-GAGGVGGTGGDGGNGATGGTGATAG----AN Mflv_5091|M.gilvum_PYR-GCK KGGTGG-------TGGAG-GTGGDGGTGGTGGTGGTGGTGGTGG------ Mvan_1264|M.vanbaalenii_PYR-1 KGGTGG-------TGGDG-GTGGTGGTGGTGGTGGTGGTGGTGG------ MSMEG_0868|M.smegmatis_MC2_155 RGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANG------ TH_3810|M.thermoresistible__bu --------------------TDADGGNGGDGGNGGSAGRGGTGG------ MAB_0010c|M.abscessus_ATCC_199 ------------------LGSTTAAGYGPSGSAGGTGLASGTAG------ MAV_4827|M.avium_104 --------------------PGAGGSGGSGGGHVPTPGAGGSGG------ MLBr_01556|M.leprae_Br4923 HAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDT------ . . Mb3543|M.bovis_AF2122/97 ----------------GAGGAGGS--SGAGGTNGSGGAGGTGGQGGAGGA Rv3508|M.tuberculosis_H37Rv AGSSATGGAGFAGGAGGEGGAGGN--SGVGGTNGSGGAGGAGGKGGTGGA MUL_4367|M.ulcerans_Agy99 -------------WAGGAGGAGGA--GGSAAFNGVNGAGGAGGNGGAGGG MMAR_0943|M.marinum_M GQDGGNGGTGGTGGQGGAGGAGGATFTGKAGTQGAGGAGGDGGAGGNAGN Mflv_5091|M.gilvum_PYR-GCK -----------------TGGAGDG----TGGTGGTGGTGGQGGQGGQGGT Mvan_1264|M.vanbaalenii_PYR-1 -----------------TGGAGDG----LGGTGGTGGTGGFGGQGGQGGT MSMEG_0868|M.smegmatis_MC2_155 --------------NGGAGGAGGVS-EGEGGTGGHGGDGGRGGDGALGGN TH_3810|M.thermoresistible__bu ----------------------------LRGVFGINGGNGRAGLGGRGXX MAB_0010c|M.abscessus_ATCC_199 ------------------------------GASALRAGGGLPGGATSGAG MAV_4827|M.avium_104 ------------------------------SGGGHVPTPGTGGPGGTGGS MLBr_01556|M.leprae_Br4923 -------------MFIDISAKVGTNIEALLEAVLLTADAALDLRANSGME . . . Mb3543|M.bovis_AF2122/97 GGAGADNP----TGIGGTGGDGGTGGAAG------AGGAGGAAGTGGTGG Rv3508|M.tuberculosis_H37Rv GGSGADNP----TGAGFAGGAGGTGGAAG------AGGAGGATGTGGTGG MUL_4367|M.ulcerans_Agy99 GGAGASG-----IGAGVAGGDGGTGGTGG------AAGTGGAAGTGGTGG MMAR_0943|M.marinum_M GGSGATGADGATVGTGVDGQDGGNGGAGG------TGGQGGAGGDGGAGS Mflv_5091|M.gilvum_PYR-GCK GGTGGQG------GLGGGGGTGGQGGTGG------TGGQGGTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQG------GLGGVGGTGGTGGTGG------TGGQGGTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GGTGGVG-----LGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGR TH_3810|M.thermoresistible__bu XXGGGVG-------AAVRSGNGVFSGGGG----------TPSAGFGVPTT MAB_0010c|M.abscessus_ATCC_199 ANPAAIG------AAGVRGGAMGPMGMMG------GAGAHGKGGHGEDDD MAV_4827|M.avium_104 GGGHVPTP-----GAGTPGGSGGGHLPFP--------GAGSTPGGSGGGH MLBr_01556|M.leprae_Br4923 AQGVAIEAHLD-RGRGPVATVLVQRGTLR-----IGDSVVAGDAYGRVRR . . . . Mb3543|M.bovis_AF2122/97 MIGTTGNAGVGGAGGQGGDGG----------------------------- Rv3508|M.tuberculosis_H37Rv VVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGA MUL_4367|M.ulcerans_Agy99 AAGAAGSAGDGGAGGAGGAGDDGSAG------------------------ MMAR_0943|M.marinum_M TTGNQGGGGAGGNGGGGGAGGNGGSGANGADGSISGLGGQAGGNGGDGGD Mflv_5091|M.gilvum_PYR-GCK TGGTGGAGGDGGLGGLGGFGG----------------------------- Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGAGGDGGLGGLGGFGG----------------------------- MSMEG_0868|M.smegmatis_MC2_155 IRVNNGTATGTATGGNGGNGGNGD-------------------------- TH_3810|M.thermoresistible__bu IQFPAGSCTSRAVSREG--------------------------------- MAB_0010c|M.abscessus_ATCC_199 EHETPAILINLDNTYEFMGDLP---------------------------- MAV_4827|M.avium_104 LPTPGAGTPGGGLGGFGGGHAPAP-------------------------- MLBr_01556|M.leprae_Br4923 MVDEHGVDIEAALPSSPVQVIG---------------------------- . Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGINGAGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGV MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0943|M.marinum_M AGVGGSGGDGGAGLSVG--------------------AHGATGNVVANGG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------AGGAGADADQ--------------------- Rv3508|M.tuberculosis_H37Rv GLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGA MUL_4367|M.ulcerans_Agy99 -----VVSGDPGTAGKAGGAGGAGGVGGNGVAGGVNGSGGAGG------- MMAR_0943|M.marinum_M NGGQGGNGGNALIGTSDGGAGGAGGAGGKAWLMGDGGSGGHGG------- Mflv_5091|M.gilvum_PYR-GCK -------------------SGGTGGQGGL--------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------VGGTGGQGGQ--------------------- MSMEG_0868|M.smegmatis_MC2_155 ---------------ADGHRGGKGGDGGEALIRATVIGSNASG------- TH_3810|M.thermoresistible__bu ------------------IMPSSRAASAR--------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------KASPAVIGDWS-------------------- MAV_4827|M.avium_104 -------------------GGGLGGGGGHAP------------------- MLBr_01556|M.leprae_Br4923 -------------------FTSVPGAGDNFLVVD---------------- . . Mb3543|M.bovis_AF2122/97 ---------------------------------PGATGG----------- Rv3508|M.tuberculosis_H37Rv STTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGG MUL_4367|M.ulcerans_Agy99 ------------------------------AGGAGGTGGAGASG------ MMAR_0943|M.marinum_M -------------------NGGAGGSSPQGSGGGGGNGGAGGTGGDAG-- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------GGPGGS---------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------GGPGGS---------- MSMEG_0868|M.smegmatis_MC2_155 ----------------------------TATGGDGGNGGTLGATNGTGG- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 --------------------------------TGFAGGAGGAGGAGGS-- Rv3508|M.tuberculosis_H37Rv GFGGAAGKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGS-- MUL_4367|M.ulcerans_Agy99 ------------------------------VPASVDGGDGGAGGAGGA-- MMAR_0943|M.marinum_M ----------------------------LQEGGGGTGGNGGNGGAGGTGK Mflv_5091|M.gilvum_PYR-GCK -----------------------------------TGGAGGAGGQAGT-- Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------TGGAGGAGGQAGV-- MSMEG_0868|M.smegmatis_MC2_155 ------AATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEA TH_3810|M.thermoresistible__bu ---------------------------------------AGAACASST-- MAB_0010c|M.abscessus_ATCC_199 -----------------------------------EQEKADKQAQERE-- MAV_4827|M.avium_104 ------------------------------------APGGGLGGFGGG-- MLBr_01556|M.leprae_Br4923 -----------------------------------EDRIARQIADRRS-- . Mb3543|M.bovis_AF2122/97 ---SGAGGTNGSGGAGG--------------------------------- Rv3508|M.tuberculosis_H37Rv ---AGAGGINGAGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGN MUL_4367|M.ulcerans_Agy99 ---AGTGGSGGSAGNTG--------------------------------- MMAR_0943|M.marinum_M -ASSATGGIGGGGGNGGAAG------------------------------ Mflv_5091|M.gilvum_PYR-GCK ---AGKGGLFGGSGSAG--------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---AGKGGLFGGSGSAG--------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGPSAVASGIGAGGNGGD-------------------------------- TH_3810|M.thermoresistible__bu ---SRSRRSFCCSRA----------------------------------- MAB_0010c|M.abscessus_ATCC_199 ---KRRYKKLGWDVEFE--------------------------------- MAV_4827|M.avium_104 ---HSGGGLGGLGGGHK--------------------------------- MLBr_01556|M.leprae_Br4923 ---ARKRNALAARSRKRIS------------------------------- Mb3543|M.bovis_AF2122/97 -------------------TGGQGGAGGAG-------------------- Rv3508|M.tuberculosis_H37Rv GGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQ MUL_4367|M.ulcerans_Agy99 -------------------AGGAGGAGGAGG------------------- MMAR_0943|M.marinum_M ----------QVGDGGGGGTGGNGGNGGAGRDGAMGGTGG---------- Mflv_5091|M.gilvum_PYR-GCK -------------------KAGATGAAGASG------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------TAGVTGASGASG------------------- MSMEG_0868|M.smegmatis_MC2_155 -----------------GIDGGLGGNGGDGVVN----------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ----------ISFSNGS--NGGTGGTGGVG-------------------- Rv3508|M.tuberculosis_H37Rv GGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDA MUL_4367|M.ulcerans_Agy99 ----------SAASTGVNGDGGAGGAGGVGG------------------- MMAR_0943|M.marinum_M ----------IGGDAGMVGNGGGGGTGGNGG------------------- Mflv_5091|M.gilvum_PYR-GCK ------------------GKGAQGATGAQG-------------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------GKGAQGATGAQG-------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------TTANAANPGSATGTATGGDGG------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ----------LEDLDSALKETSQLNLILKGD------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GSGGGGGFGGAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQGG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0943|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv AGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGDGG MUL_4367|M.ulcerans_Agy99 -----------------------------------------------LGG MMAR_0943|M.marinum_M ------------------------------------------------NG Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ---------GTGGDGG-----NAGTG-AGDP----GKGGTGGTGGSGGAG Rv3508|M.tuberculosis_H37Rv NAGFGAGVPGDGGDGG-----NAGFG-AGVP----GDGGIGGTGGAGGAG MUL_4367|M.ulcerans_Agy99 DSAATAGGGGAGGDGG-----KGGAGGAGVNGVGGGDGGKGGTGGAGGAG MMAR_0943|M.marinum_M GNGNAGGGPGIGGNGA-----EGGAGGSGGS--SSGNGGAGGKGGSGGTG Mflv_5091|M.gilvum_PYR-GCK ---------ATGAQGA-----TGATGAAGKA------GATGAAGAAGAAG Mvan_1264|M.vanbaalenii_PYR-1 ---------ATGAQGA-----TGATGASGAQ------GSAGSAGSAGVAG MSMEG_0868|M.smegmatis_MC2_155 ---KATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ---------NAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLA Mb3543|M.bovis_AF2122/97 GS------------GGAN-------------------------------- Rv3508|M.tuberculosis_H37Rv GAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGA MUL_4367|M.ulcerans_Agy99 GAGSDG---IIPSNGGLGG------------------------------- MMAR_0943|M.marinum_M GAGQFG----NTGGNGANG------------------------------T Mflv_5091|M.gilvum_PYR-GCK SAGTTG-------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 SAGTTG-------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGNALVMAAGTTGVATG------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 SASDAIIIG----------------------------------------- Mb3543|M.bovis_AF2122/97 ---------FNGGTGGTGGTG----------------------------- Rv3508|M.tuberculosis_H37Rv GGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGD MUL_4367|M.ulcerans_Agy99 ----------NGGNGGNGGQAFG--------------------------- MMAR_0943|M.marinum_M FDNGGDGRGGAGGTGGTGGTGGDGGVGGNGGAGG---------------- Mflv_5091|M.gilvum_PYR-GCK ----------AQGSAGTNGAN----------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------AQGSAGTNGAN----------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------NTATGGDGGAATTAG------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ---------------------------------------GTGGKGGMGG- Rv3508|M.tuberculosis_H37Rv GGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGD MUL_4367|M.ulcerans_Agy99 --------------------------------------DGVGGAGGIGGK MMAR_0943|M.marinum_M ------------------KAISPTGQDGAQGAGGNGGAGGTGGNGGFGGS Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------GANGSQGAAG- Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------GANGSQGAAG- MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------ATGGAGGFSNI TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGG MUL_4367|M.ulcerans_Agy99 GGNAAIG------------------------------------------- MMAR_0943|M.marinum_M GGSGADGTLFSSLAG----------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AAIHGAITDSTAISG----------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv AGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0943|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ---------------IAGDGGPGGDGGNAGVG------------------ Rv3508|M.tuberculosis_H37Rv GAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAG MUL_4367|M.ulcerans_Agy99 --------------TIVINGGVGGAGGSGGLGGATEDG------------ MMAR_0943|M.marinum_M ------------TGGTGGNGGTGGDGGAGGAGGAPGTGLIPGSTG----- Mflv_5091|M.gilvum_PYR-GCK --------------KAGATGTTGATGAAGEDGDA---------------- Mvan_1264|M.vanbaalenii_PYR-1 --------------KAGATGTTGATGAAGDAGDP---------------- MSMEG_0868|M.smegmatis_MC2_155 -------------HGGAGNGGNGGKGADGWVQAYDPAGPVG--------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------FNVRAEGKATELASREGVEIR---------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0943|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGI MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0943|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0943|M.marinum_M -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -----------------------GKGGTNGNG----GSGGTGGT-GGPGG Rv3508|M.tuberculosis_H37Rv DGGNGGAGGAGGNGGAGGLGGGGGTGGTNGNG----GLGGGGGN-GGAGG MUL_4367|M.ulcerans_Agy99 ---------------VGGVGCAGGAGGNGGRGDMLFTVGGSGGT-GGDGG MMAR_0943|M.marinum_M ---------------AAGATGRAGTGGFGGNGGLG-SAFGPGGT-GGNGG Mflv_5091|M.gilvum_PYR-GCK -----------------------GSGGSGING----GAGGAGGA-GGEGG Mvan_1264|M.vanbaalenii_PYR-1 -----------------------GSEAVDING----GAGGAGGA-GGEGG MSMEG_0868|M.smegmatis_MC2_155 ----------------SKIANSSAVAGNGGDG----GVNGTGGASGGDGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ----------------------YYLVIYQAIDDIEKALRGMLKPIYEENQ Mb3543|M.bovis_AF2122/97 SGGAPTGSGTGGKGGAGGD--GGDGADGGAATGVGDGGDGGN-------G Rv3508|M.tuberculosis_H37Rv AGGTPTGSGTEGTGGDGGD--AGAGGNGGSATGVGNGGNGGD-------G MUL_4367|M.ulcerans_Agy99 GGGSASGSGTGGSGGTGGV--GGIGGDGK------LGGFGGD-------G MMAR_0943|M.marinum_M SGGSSSTS-AGGGGGTGGA--GGTGFDGSAGGAGGNGGQGGDGLGTAGDG Mflv_5091|M.gilvum_PYR-GCK EGGDGGKGGAGAEGGAGGG--GGAGGSGA--------------------G Mvan_1264|M.vanbaalenii_PYR-1 EGGAGGAGGDGSEGGAGGS--GGAGGSGT--------------------G MSMEG_0868|M.smegmatis_MC2_155 NGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGG-----AG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 LGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVT Mb3543|M.bovis_AF2122/97 GNGGNGGTGVGSPGGL--GGAGGTGGLGGAG--------AGGGADGDDGD Rv3508|M.tuberculosis_H37Rv GNGGDGGN--GAPGGF--GGGAGAGGLGGSG--------AGGGTDGDDGN MUL_4367|M.ulcerans_Agy99 GDGGDGGF--GVIGGQ--GGGGGFGGLGGTG--------AGG-APSDKGI MMAR_0943|M.marinum_M GNGGTGGKGSNAPIGFSFGGAGGKGGTGGTGGTAHLGPLAIHGQSGDPGQ Mflv_5091|M.gilvum_PYR-GCK GAGGAGGS----------GGSGGSGGSGGSG-----------GAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 GAGGAGGS----------GGSGGSGGAGGSG-----------GAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 GNGGTGGTT---------AGGSGNGGNGGNG--------GNGGADGTPGT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0010c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 SLRREKDDVTEVREGFECGMTLGYSDIKEGD-----------VIESYELV Mb3543|M.bovis_AF2122/97 DGQPGNNGS---------------- Rv3508|M.tuberculosis_H37Rv GGSPGTDGS---------------- MUL_4367|M.ulcerans_Agy99 NGEPGNPG----------------- MMAR_0943|M.marinum_M SGPPVVDGNGGAGGQGGPGGAGGSF Mflv_5091|M.gilvum_PYR-GCK ------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------------- MSMEG_0868|M.smegmatis_MC2_155 AGTTGANNP---------------- TH_3810|M.thermoresistible__bu ------------------------- MAB_0010c|M.abscessus_ATCC_199 ------------------------- MAV_4827|M.avium_104 ------------------------- MLBr_01556|M.leprae_Br4923 EKQRA--------------------