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SAPNDSVADGSEDEILDRTGPIIPIKLGAHAKRQRAEAAAQQQQQTQPEPLPSQLPPRGPLSIVDAVPPH DPLVDLPPAIGDALGAQLRSEILPPLRRPASAGWRKWVYRGSFGVINPGESREEAELRELTAVVRSPWRG IHSLAVLGGNGGVGKTMITAALGSVLSELRRKDMVLATDADPGQSANLASWIDPSASSTFADVLAQHEPE RNFDLRFFVGQNSETGLDVLAANSHSVRPRGELNAEIYTQAHHRLQRLYSLLITDTGVDFWHPVMPGVLR CANGVVLVAAATPVGAEGAVRAIEWLIAEGYEHLIPRMVVVINHVRGYDNREDRRNSERLVAAMVARFHR WISPNHIVAVPYDPHIATAGPLDIQQLQPETWHGLLTAAASVSAGLASAWSV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0058c | - | - | 100% (403) | hypothetical protein MAB_0058c |
| M. abscessus ATCC 19977 | MAB_3972c | - | 5e-40 | 32.92% (322) | hypothetical protein MAB_3972c |
| M. abscessus ATCC 19977 | MAB_0630 | - | 1e-34 | 31.15% (382) | hypothetical protein MAB_0630 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3906 | - | 3e-40 | 33.33% (360) | hypothetical protein Mb3906 |
| M. gilvum PYR-GCK | Mflv_0048 | - | 2e-40 | 31.97% (366) | hypothetical protein Mflv_0048 |
| M. tuberculosis H37Rv | Rv3876 | - | 3e-40 | 33.33% (360) | hypothetical protein Rv3876 |
| M. leprae Br4923 | MLBr_00048 | - | 2e-37 | 30.67% (375) | hypothetical protein MLBr_00048 |
| M. marinum M | MMAR_5436 | - | 2e-42 | 34.09% (352) | hypothetical protein MMAR_5436 |
| M. avium 104 | MAV_0156 | - | 3e-38 | 33.01% (312) | hypothetical protein MAV_0156 |
| M. smegmatis MC2 155 | MSMEG_0053 | - | 8e-46 | 34.29% (350) | hypothetical protein MSMEG_0053 |
| M. thermoresistible (build 8) | TH_0884 | - | 7e-40 | 34.43% (305) | conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0080 | - | 8e-40 | 31.77% (362) | hypothetical protein Mvan_0080 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5436|M.marinum_M -------------------------------MNEREEFLRDRVRPDQPSV
MSMEG_0053|M.smegmatis_MC2_155 -------------------------------MADPDDTLRRELGWTGPEE
MAV_0156|M.avium_104 --------------------------------------------------
MAB_0058c|M.abscessus_ATCC_199 -----------------------------------------------MSA
Mb3906|M.bovis_AF2122/97 MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
Rv3876|M.tuberculosis_H37Rv MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
MLBr_00048|M.leprae_Br4923 MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPPPIIPTCTTTPNGEVA
Mvan_0080|M.vanbaalenii_PYR-1 MSADYDRLFHSPDAARTADE------------------------SDRETP
Mflv_0048|M.gilvum_PYR-GCK MSFRAQQRFSDP--------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
MMAR_5436|M.marinum_M PDAS--RSHQRSGMHRTATDASG-PPVAPTHQ----PRPAPPRPPTPQPS
MSMEG_0053|M.smegmatis_MC2_155 DDFEPDTGPTRPTLRPEPPSIPGRPPVSPTPPNPVNPDAEDRVPADPDAE
MAV_0156|M.avium_104 --------------------------------------------------
MAB_0058c|M.abscessus_ATCC_199 PNDSVADGSEDEILDRTG-------PIIPIKLGAHAKRQRAEAAAQQQQQ
Mb3906|M.bovis_AF2122/97 PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
Rv3876|M.tuberculosis_H37Rv PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
MLBr_00048|M.leprae_Br4923 SPMPD-----WSEQLPPNPPAASKSPLPPMPIGSSVQPPP--ASSESPRA
Mvan_0080|M.vanbaalenii_PYR-1 PAGRD-------TVAPPGGAPNGDATPPPMPAARAQ------AMQAPPSW
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
MMAR_5436|M.marinum_M PVPPRGA-------------------------------------------
MSMEG_0053|M.smegmatis_MC2_155 RARTTFR-------------------------------------------
MAV_0156|M.avium_104 --------------------------------------------------
MAB_0058c|M.abscessus_ATCC_199 TQPEPLP-------------------------------------------
Mb3906|M.bovis_AF2122/97 PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
Rv3876|M.tuberculosis_H37Rv PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
MLBr_00048|M.leprae_Br4923 PMPVSAP---PRSPAASLMPISEPPQWPP----------AEAPEHQFAKA
Mvan_0080|M.vanbaalenii_PYR-1 QTEVMSP-------------ITG--------------------------L
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
MMAR_5436|M.marinum_M ------------------NPHPPPPPAPPSVPAPPPPPVAHPPN------
MSMEG_0053|M.smegmatis_MC2_155 ------------------EPTQPSPPQQPSQPPPPPPPSALHPRPDPWEQ
MAV_0156|M.avium_104 --------------------------------------------------
MAB_0058c|M.abscessus_ATCC_199 ------------------SQLPPRGPLSIVDAVPPHDPLVDLPP------
Mb3906|M.bovis_AF2122/97 APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
Rv3876|M.tuberculosis_H37Rv APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
MLBr_00048|M.leprae_Br4923 EPPSVPIPINEP-SPAKPATPMPMTPIDGSQRTPVTSPEPSLAEFEAQPP
Mvan_0080|M.vanbaalenii_PYR-1 QPPNQP--------------AAQRVPDNGMMRAPQAPPVGARHEQQRSAP
Mflv_0048|M.gilvum_PYR-GCK ---------------------------MAPVPAEWTAPTPPEGVVPVVAA
TH_0884|M.thermoresistible__bu --------------------------------------------------
MMAR_5436|M.marinum_M ---GHNSPPQAAP--HEPMPEVP---------------PPSLWAEPTPAR
MSMEG_0053|M.smegmatis_MC2_155 RVPGWNAPQYGPPPGNQPWPQAGGFGGGPGQPPHVPPGPPQSYADRIRAS
MAV_0156|M.avium_104 ----------------------------------------------MRIT
MAB_0058c|M.abscessus_ATCC_199 --------------------------------------AIGDALGAQLRS
Mb3906|M.bovis_AF2122/97 P-PAP---SRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATG
Rv3876|M.tuberculosis_H37Rv P-PAP---SRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATG
MLBr_00048|M.leprae_Br4923 ATPKPSLLPRPMSSPPEAPRPSANQHSRHARRGHHHRDETQQANPASATE
Mvan_0080|M.vanbaalenii_PYR-1 P-PAP----RPAPAPPPS---------------QFYGEPTDQRQPTAPTS
Mflv_0048|M.gilvum_PYR-GCK ATPS-----------------------------------TELVPYRELST
TH_0884|M.thermoresistible__bu ---------------------------------------------VDLST
MMAR_5436|M.marinum_M --TPGEPPSTDH--------------------------------------
MSMEG_0053|M.smegmatis_MC2_155 DLVPPKRQPPSG--------------------------------------
MAV_0156|M.avium_104 DLAAPRKIPPGS--------------------------------------
MAB_0058c|M.abscessus_ATCC_199 EILPPLRRPASA--------------------------------------
Mb3906|M.bovis_AF2122/97 PSIQARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSP
Rv3876|M.tuberculosis_H37Rv PSIQARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSP
MLBr_00048|M.leprae_Br4923 PMIAPRARTAELRQAP------------------------HAAAEPAPTQ
Mvan_0080|M.vanbaalenii_PYR-1 AAAMGNHRAIDA--------------------------------------
Mflv_0048|M.gilvum_PYR-GCK VALLGALPKAPS--------------------------------------
TH_0884|M.thermoresistible__bu TALLGQRRPAPS--------------------------------------
MMAR_5436|M.marinum_M --------------------------------------------------
MSMEG_0053|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0156|M.avium_104 --------------------------------------------------
MAB_0058c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 SPQRNSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDAT
Rv3876|M.tuberculosis_H37Rv SPQRNSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDAT
MLBr_00048|M.leprae_Br4923 HLTR-----------PDGLVSHRTALHDSTATSAIG-------------V
Mvan_0080|M.vanbaalenii_PYR-1 -------------------LSHVGVR------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
MMAR_5436|M.marinum_M ---------------------------------GWRHIIRVASFGLINPR
MSMEG_0053|M.smegmatis_MC2_155 ---------------------------------GWRLLVYRATFGLVNPG
MAV_0156|M.avium_104 ---------------------------------GWRKFIYTISFHKINPG
MAB_0058c|M.abscessus_ATCC_199 ---------------------------------GWRKWVYRGSFGVINPG
Mb3906|M.bovis_AF2122/97 QKSLRPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTR--INLG
Rv3876|M.tuberculosis_H37Rv QKSLRPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTR--INLG
MLBr_00048|M.leprae_Br4923 QTGRSTGAK---------------KPSKVVAKRGWRHWVHTVTR--INLG
Mvan_0080|M.vanbaalenii_PYR-1 ------------------------SAVKMPSQRGWRHWLYVMTR--INLG
Mflv_0048|M.gilvum_PYR-GCK --------------------------------AGWRKWVYRASGRLINPG
TH_0884|M.thermoresistible__bu --------------------------------RGWRRWLYRATFRTVNLG
*** : : :*
MMAR_5436|M.marinum_M PSAAQRDAAEFEAAIRAPLRGTHKVGVLG-KGGVGKTSVAASIGSLLAEL
MSMEG_0053|M.smegmatis_MC2_155 PSAEELRQAELEAKIRGVLRGHYKIGVMG-KGGVGKTTVSATIGSIFAHL
MAV_0156|M.avium_104 ESPRERHYRDLQNRIRRHIRRQYVITVVSGKGGVGVTTLVACIGGVFREC
MAB_0058c|M.abscessus_ATCC_199 ESREEAELRELTAVVRSPWRGIHSLAVLGGNGGVGKTMITAALGSVLSEL
Mb3906|M.bovis_AF2122/97 LSPDEKYELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQV
Rv3876|M.tuberculosis_H37Rv LSPDEKYELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQV
MLBr_00048|M.leprae_Br4923 LSPDERYELDLRTRVRRPPRGSYQIGILGLKGGAGKTTVTVTLGSMFARV
Mvan_0080|M.vanbaalenii_PYR-1 LSADELYELDLHARIRRNARDSYHIGVFGLKGGVGKTAVTVALGSALASI
Mflv_0048|M.gilvum_PYR-GCK ESPKVIRHDDLLARVQQPLQGCYRVAMLSQKGGVGKTTITATLGATFAGA
TH_0884|M.thermoresistible__bu ESPKVARHNELLNRVRHPLQDCYRIAVLSLKGGVGKTTITATLGSTFGSA
* :: :: : : : :.. :**.* * : . :*. :
MMAR_5436|M.marinum_M RQQDRIVAVDADTAFGR-LSSRIDPTARGSFWDLTADRN-LASFADVVAR
MSMEG_0053|M.smegmatis_MC2_155 RQDDRVVAIDADTSFGK-LGSRVDPRAHGSYWELTSDKN-LETFADVRSR
MAV_0156|M.avium_104 RPQN-VIAIDAVPGFGT-LADRIDESPPGDYTAIINDTD-VQGYADIREH
MAB_0058c|M.abscessus_ATCC_199 RRKDMVLATDADPGQSANLASWIDPSASSTFADVLAQHE-PERNFDLRFF
Mb3906|M.bovis_AF2122/97 RADR-ILALDADPGAGN-LADRVGRQSGATIADVLAEKE-LSHYNDIRAH
Rv3876|M.tuberculosis_H37Rv RADR-ILALDADPGAGN-LADRVGRQSGATIADVLAEKE-LSHYNDIRAH
MLBr_00048|M.leprae_Br4923 RNDR-ILVVDADTSCGN-LADRAGRFSEANIADLLADKD-VKSYNDIRTH
Mvan_0080|M.vanbaalenii_PYR-1 RGDR-ILAIDADPDGGN-LADRAGRQSAATITDLLSDKE-LNRYNDIRAY
Mflv_0048|M.gilvum_PYR-GCK RGDR-VIAVDANPDRGT-LSQKVPVETPATVRHLLRDAEGVSAYSDVRRY
TH_0884|M.thermoresistible__bu RGDR-VVAVDANPDRGT-LSQKVPLQTRATVRDLLRDADRIQTYSDMRAY
* . ::. ** . . *.. . . : : : *:
MMAR_5436|M.marinum_M LGRNA-AGLHVLPGEAAVGGRR-LLDPAIYREAALRLDRHFTISIIDCGS
MSMEG_0053|M.smegmatis_MC2_155 VGNNS-AGLFVLAGESTPARRR-VLDAAIYREAVTRLDKHFSISVVDCSS
MAV_0156|M.avium_104 LGQNA-VGLDVLAGNRTSDQPR-PLVPAMFSGVLSRLRRTHTVMIVDTSP
MAB_0058c|M.abscessus_ATCC_199 VGQNSETGLDVLAANSHSVRPRGELNAEIYTQAHHRLQRLYSLLITDTGV
Mb3906|M.bovis_AF2122/97 TSVNA-VNLEVLPAPEYSSAQR-ALSDADWHFIADPASRFYNLVLADCGA
Rv3876|M.tuberculosis_H37Rv TSVNA-VNLEVLPAPEYSSAQR-ALSDADWHFIADPASRFYNLVLADCGA
MLBr_00048|M.leprae_Br4923 TSVNA-VNLEVLPAAEYSTAQH-ALSGEDWNFAAATVSKYYNVMLADCGV
Mvan_0080|M.vanbaalenii_PYR-1 TSMNA-SNLEVLSSDEYSAARR-EFNDEDWREATEIVSRYYNLVLADCGA
Mflv_0048|M.gilvum_PYR-GCK TSQGP-SRLEVLASESDPAVSE-AFSATDYVRALNILERFYSMVLTDCGT
TH_0884|M.thermoresistible__bu TSQSP-SRLEVLASESDPAVSE-AFSSDDYTRTLRVLERFYSLVLTDCGT
. .. * **.. . : : : ..: : * .
MMAR_5436|M.marinum_M TMDAPLTQEVLRDLDALIVVSSPWADGASAAAKTMEWLADRKLSGLLRRS
MSMEG_0053|M.smegmatis_MC2_155 TMDSPVTQEVLRDLDALIVVSSPWVDGAATAGQTLDWLSANGMTRLLQRT
MAV_0156|M.avium_104 DLEHEVMKPVLENTDTLVFVSGITADRSRPVLRAVDYLRSQGYHELVSRS
MAB_0058c|M.abscessus_ATCC_199 DFWHPVMPGVLRCANGVVLVAAATPVGAEGAVRAIEWLIAEGYEHLIPRM
Mb3906|M.bovis_AF2122/97 GFFDPLTRGVLSTVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRA
Rv3876|M.tuberculosis_H37Rv GFFDPLTRGVLSTVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRA
MLBr_00048|M.leprae_Br4923 GLFDPVTRGVLSTASGVVIVTSTSVDAARQAAIALDWLRHNGYQDLLSRA
Mvan_0080|M.vanbaalenii_PYR-1 GLFQPGARGVLSTVSGLVIVASASIDGARQAAITMDWLRQNGYQDLLGRS
Mflv_0048|M.gilvum_PYR-GCK GMLHSAMSAVIDKADVLVVISSGSADGARSASATLDWLDAHGHDDMVRNS
TH_0884|M.thermoresistible__bu GLIHSAMSAVLANADVLIVISSGSVDGARSAAATLDWLDAHGHQDMVRNS
: *: . ::.::. : . ::::* . : .
MMAR_5436|M.marinum_M VVVLNDS--------DGHSDKRTRSVLAREFVD------HGQQVVEVPFD
MSMEG_0053|M.smegmatis_MC2_155 VVVLNDS--------DGHADKRTRSILLNQFAG------QGQAVVEIPFD
MAV_0156|M.avium_104 TVIVNHT--------DQITDKDALAYLTERFTK------VGATVEALPFD
MAB_0058c|M.abscessus_ATCC_199 VVVINHVRGY-----DNREDRRNSERLVAAMVARFHRWISPNHIVAVPYD
Mb3906|M.bovis_AF2122/97 CVVINHIMPG--------EPNVAVKDLVRHFEQ----QVQPGRVVVMPWD
Rv3876|M.tuberculosis_H37Rv CVVINHIMPG--------EPNVAVKDLVRHFEQ----QVQPGRVVVMPWD
MLBr_00048|M.leprae_Br4923 CVVINHVMPK--------EPNIASKDLVQQFEQ----QIQPGRVVVLPWD
Mvan_0080|M.vanbaalenii_PYR-1 CVVINHVTPG--------KPNIDVEDLVQQFER----HVPAGRVIVLPWD
Mflv_0048|M.gilvum_PYR-GCK IAVINAVRPRGRRGTSRGTAKVDLDKIVDHFTR----RCR--AVCQVPFD
TH_0884|M.thermoresistible__bu IAVINAVRPR--------SGKVDLQKVVDHFSR----RCR--AVKMVPFD
.::* . : : : :*:*
MMAR_5436|M.marinum_M PHLRPGGVIDVSHELEPGTRLKFLQIAATITGHFAARSAADDDPRPTENV
MSMEG_0053|M.smegmatis_MC2_155 GHLRPGGVVDI-QEMSPKVRRKFLEVAAALADHFPT---SDDHTRERS--
MAV_0156|M.avium_104 PHLAKGGIIDTVHELKKKTRLRLFEITAGLADKYIP-----DAERAVP--
MAB_0058c|M.abscessus_ATCC_199 PHIATAGPLDI-QQLQPETWHGLLTAAASVSAGLAS-------AWSV---
Mb3906|M.bovis_AF2122/97 RHIAAGTEISL-DLLDPIYKRKVLELAAALSDDFERAGRR----------
Rv3876|M.tuberculosis_H37Rv RHIAAGTEISL-DLLDPIYKRKVLELAAALSDDFERAGRR----------
MLBr_00048|M.leprae_Br4923 KHIAAGTEIRL-DRLDPLYRRRILELAAALSDDFERAGRH----------
Mvan_0080|M.vanbaalenii_PYR-1 KHIAAGTEIQL-SLLGKTFNRKIVELAAALSDDFDRLERR----------
Mflv_0048|M.gilvum_PYR-GCK AHLEEGAEISL-DRLRPQTRESLLELAAAVADGFPGARNRSDPAD-----
TH_0884|M.thermoresistible__bu PHLEEGAEIDL-DQLKPQTRQALLELAAVVADGFPGAQQLQSPPF-----
*: . : : .. :* ::
MMAR_5436|M.marinum_M ASET
MSMEG_0053|M.smegmatis_MC2_155 ----
MAV_0156|M.avium_104 ----
MAB_0058c|M.abscessus_ATCC_199 ----
Mb3906|M.bovis_AF2122/97 ----
Rv3876|M.tuberculosis_H37Rv ----
MLBr_00048|M.leprae_Br4923 ----
Mvan_0080|M.vanbaalenii_PYR-1 ----
Mflv_0048|M.gilvum_PYR-GCK ----
TH_0884|M.thermoresistible__bu ----