For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4522 | - | - | 100% (391) | putative caib/baif family protein |
| M. thermoresistible (build 8) | TH_3752 | - | 9e-53 | 35.25% (366) | PUTATIVE - |
| M. thermoresistible (build 8) | TH_3339 | - | 3e-34 | 31.77% (384) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1897 | - | 7e-31 | 30.60% (366) | hypothetical protein Mb1897 |
| M. gilvum PYR-GCK | Mflv_5186 | - | 8e-28 | 29.60% (402) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv1866 | - | 3e-31 | 30.87% (366) | hypothetical protein Rv1866 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 9e-30 | 30.05% (396) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_2745 | - | 2e-31 | 29.82% (389) | acyl-CoA transferase/dehydratase |
| M. avium 104 | MAV_2852 | - | 2e-31 | 30.45% (381) | caib/baif family protein |
| M. smegmatis MC2 155 | MSMEG_2171 | - | 2e-31 | 30.71% (394) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_1046 | - | 2e-27 | 30.61% (392) | acyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_1126 | - | 2e-31 | 30.94% (404) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1897|M.bovis_AF2122/97 ----------------------MVTRLLADLGADVLKVQPPGGSPGRHVR
Rv1866|M.tuberculosis_H37Rv ----------------------MVTRLLADLGADVLKVEPPGGSPGRHVR
MMAR_2745|M.marinum_M --MADQLLAAVRVLDLSGGTADTVARLLADLGADVLKVEPPGGSPGRNQA
MAV_2852|M.avium_104 MQMADRLLDAVRVLDLSNGVADAVTRLFADLGADVLKVEPPGGCLGRDAL
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5186|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1126|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1046|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2171|M.smegmatis_MC2_155 --------------------------------------------------
TH_4522|M.thermoresistible__bu --------------------------------------------------
Mb1897|M.bovis_AF2122/97 PTLAGTSIGFAMHNANKRSAVLNPLDESDRRRFLDLAASADIVVDCGLPG
Rv1866|M.tuberculosis_H37Rv PTLAGTSIGFAMHNANKRSAVLNPLDESDRRRFLDLAASADIVVDCGLPG
MMAR_2745|M.marinum_M PTLAGASIPFAVHNANKRSVVLDPNDAADRARLLELAAGADILVDSGLPG
MAV_2852|M.avium_104 PTLRGASIPFAVHNANKRSTVLDPFDDEDCARFLDLAADADIVVDTGVDE
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5186|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1126|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1046|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2171|M.smegmatis_MC2_155 --------------------------------------------------
TH_4522|M.thermoresistible__bu --------------------------------------------------
Mb1897|M.bovis_AF2122/97 QAAAYGASCAELADRYRHLVALSITDFGAAGPRSSWRATDPVLYAMSGAL
Rv1866|M.tuberculosis_H37Rv QAAAYGASCAELADRYRHLVALSITDFGAAGPRSSWRATDPVLYAMSGAL
MMAR_2745|M.marinum_M QASSYGTSCVELADRCPHLVVLSFTDFGASGPRSSWRATDAVLYAMSGSL
MAV_2852|M.avium_104 RGAMFGTSAEELAARYPHLVVLSITDFGATGPRSSWRATDPVLYAMCGAL
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5186|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1126|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1046|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2171|M.smegmatis_MC2_155 --------------------------------------------------
TH_4522|M.thermoresistible__bu --------------------------------------------------
Mb1897|M.bovis_AF2122/97 SRSGPTAGTPVLPPDGIASATAAVQAAWAVLVAYFNRLRCGTGDYIDFSR
Rv1866|M.tuberculosis_H37Rv SRSGPTAGTPVLPPDGIASATAAVQAAWAVLVAYFNRLRCGTGDYIDFSR
MMAR_2745|M.marinum_M SRSGPTTGTPVLPPDGIASATAAVQATWSVLAAYYNKLRCGTGDYIDFSR
MAV_2852|M.avium_104 SRSGPTTGTPVLPPDGIASATAAVQAAWAALAAYYNRLRCGTGDYIDFSW
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5186|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1126|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1046|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2171|M.smegmatis_MC2_155 --------------------------------------------------
TH_4522|M.thermoresistible__bu --------------------------------------------------
Mb1897|M.bovis_AF2122/97 FDAVVMALDPPFGAHGQVAAGIRSTGRWRGRPKNQDAYPIYPCRDGYVRF
Rv1866|M.tuberculosis_H37Rv FDAVVMALDPPFGAHGQVAAGIRSTGRWRGRPKNQDAYPIYPCRDGYVRF
MMAR_2745|M.marinum_M FDAVVMALDPAFGAHGQVAAGIRSSARWRGRPKNQDAYPIYPCQDGYVRL
MAV_2852|M.avium_104 FDAVVMALDPAFGAHGQAAAGIRRSGRWRGRPKNQDAYPIYPCQDGYVRL
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5186|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1126|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1046|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2171|M.smegmatis_MC2_155 --------------------------------------------------
TH_4522|M.thermoresistible__bu --------------------------------------------------
Mb1897|M.bovis_AF2122/97 CVMAPRQWRGLRRWLGEPEDFQDPKYDVIGARLAAWPQISVLVAKLCAEK
Rv1866|M.tuberculosis_H37Rv CVMAPRQWRGLRRWLGEPEDFQDPKYDVIGARLAAWPQISVLVAKLCAEK
MMAR_2745|M.marinum_M CVMAPRQWRGLRRWLGEPPDFQDPKYDVIGARFAAWPQISELVAALFAPQ
MAV_2852|M.avium_104 CVMAPRQWHGLRRWLGEPEDFQDPKYDVIGARFAVWPQISELLQKLFAGQ
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5186|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1126|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1046|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2171|M.smegmatis_MC2_155 --------------------------------------------------
TH_4522|M.thermoresistible__bu --------------------------------------------------
Mb1897|M.bovis_AF2122/97 TMKELVAAGQALGVPITAVLTPSRILASEHFQAVGAITDAELVPGVRTGV
Rv1866|M.tuberculosis_H37Rv TMKELVAAGQALGVPITAVLTPSRILASEHFQAVGAITDAELVPGVRTGV
MMAR_2745|M.marinum_M TMKELVAAGQAHGVPIAAVLTPSRILASEHFQAVGAITEAELVPGVHTKV
MAV_2852|M.avium_104 TMKDLVAAGQAHGVPIAAVLTPSQILGSDHFQAVGAITDAELVPGVHTAV
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5186|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1126|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1046|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2171|M.smegmatis_MC2_155 --------------------------------------------------
TH_4522|M.thermoresistible__bu --------------------------------------------------
Mb1897|M.bovis_AF2122/97 PTGYFVVDGKRAGFRTPAPAAGQDEPRWLADPAPVPPPSGRVGGYPFEGL
Rv1866|M.tuberculosis_H37Rv PTGYFVVDGKRAGFRTPAPAAGQDEPRWLADPAPVPPPSGRVGGYPFEGL
MMAR_2745|M.marinum_M PTGYFVVNEQRAGFHTPAPAVGQDQPRWLAGPAPELASTASVGGCPLEGL
MAV_2852|M.avium_104 PSGYFVVDGRRAGFRAPVPAAGRDEPYWRGAPSVVPSPAGRLGDHPFAGL
MAB_4651c|M.abscessus_ATCC_199 ------------------------------------------MTGALDGI
Mflv_5186|M.gilvum_PYR-GCK ----------------------------------------MPSAGPLSGV
Mvan_1126|M.vanbaalenii_PYR-1 ----------------------------------------MSSAGPLSGV
MUL_1046|M.ulcerans_Agy99 ------------------------------------------MAGPVEGI
MSMEG_2171|M.smegmatis_MC2_155 ---------------------------MTDTIHPSDGPQLALSAGPLADL
TH_4522|M.thermoresistible__bu ------------------------------------------MELAFTGL
.. .:
Mb1897|M.bovis_AF2122/97 RILDLGIIVAGGELSRLFGDLGAEVIKVESADHPDGLRQTR-----VGDA
Rv1866|M.tuberculosis_H37Rv RILDLGIIVAGGELSRLFGDLGAEVIKVESADHPDGLRQTR-----VGDA
MMAR_2745|M.marinum_M RILDLGIIVAGGELSRLFGDLGAEVIKVESADYPDGLRQAR-----AGDA
MAV_2852|M.avium_104 RILDLGIIVAGGELSRLFGDLGADVIKVESADYPDGLRQAR-----ASEA
MAB_4651c|M.abscessus_ATCC_199 RVLELGTLIAGPFAGRLLGDMGAEVLKIEPPGAPDPLRTWG-----QAEV
Mflv_5186|M.gilvum_PYR-GCK KVVDLTAVVAGPYCTQIMADMGADVVKVEAPQGDNARYIS------VGPE
Mvan_1126|M.vanbaalenii_PYR-1 NVVDLTAVVAGPYCTQIMADMGADVVKVEPPQGDNARYIS------VGPE
MUL_1046|M.ulcerans_Agy99 KVVELGVWVAAPAAAAILADWGADVIKIEPPAGDPGRLFGRM----LGCD
MSMEG_2171|M.smegmatis_MC2_155 TVVDLTRALAGPHAAMMLGDLGADVIKVESPVGGDDTRGWGPPFIEPTGA
TH_4522|M.thermoresistible__bu RVVEIADDPAGEHTGKLLADQGATVVKIEPEGGATSRHIGPWAG--GVQD
:::: *. ::.* ** *:*:*.
Mb1897|M.bovis_AF2122/97 MSESFAWTH--RNHLALGLDLRNSEGKAIFGRLVAESDAVFANFKPGTLT
Rv1866|M.tuberculosis_H37Rv MSESFAWTH--RNHLALGLDLRNSEGKAIFGRLVAESDAVFANFKPGTLT
MMAR_2745|M.marinum_M MSESFAWTH--RNHRALGLDLRSPEGKQIFGRLVAAADAVFANFKPGTLT
MAV_2852|M.avium_104 MGESFAWTH--RNNRALGLDLRSAQGKTIFARLVAEADAVFANFKPGTLA
MAB_4651c|M.abscessus_ATCC_199 DGHHVFWTVHARNKKAITLDLRTEAGRALFLDLVDKSDVIVENFRPGTLE
Mflv_5186|M.gilvum_PYR-GCK PGLSGVFTNVNRGKRSVVLDLQTDAGKDALRTLVARADVFIHSMRAAAIA
Mvan_1126|M.vanbaalenii_PYR-1 PGLSGVFTNVNRGKRSAVLDLQTDEGKRALRALVGQADVFIHSMRAAAIA
MUL_1046|M.ulcerans_Agy99 LGMNPPFEMDNRCKRSVVLDLSTDTGRELAYELLSDADVFITNVRPAALR
MSMEG_2171|M.smegmatis_MC2_155 ERESTYFLSANRNKKSVTLDLKSPLGRDALTELLRRADVLMENFRPGVLD
TH_4522|M.thermoresistible__bu VDRSLHFWTYNTSKKSVVLPD-DDEGRAARDRLIADADVLLTTGRPVDLE
: : : * *: *: :*... . :. :
Mb1897|M.bovis_AF2122/97 SLGFSYDVLHAFNPRIVLAGSSAFGNRGPWSTRMGYGPLVRAATG-VTRV
Rv1866|M.tuberculosis_H37Rv SLGFSYDVLHAFNPRIVLAGSSAFGNRGPWSTRMGYGPLVRAATG-VTRV
MMAR_2745|M.marinum_M SLGFNYANLHALNPHIVLAGSSAFGNRGPWSTRLGYGPLVRATTG-VTRV
MAV_2852|M.avium_104 ALGFSYEQLRAINPRIVLAESSAFGDTGPWSTRMGYGPLVRATTG-VTRL
MAB_4651c|M.abscessus_ATCC_199 RWGLGYDVLAQRNKGIILVRVSGYGQTGPDAHKAGYASVAEAASG-LRHL
Mflv_5186|M.gilvum_PYR-GCK KLGFDYAAVADLNPSIVYTNCYGYGRTGPYAARPAYDDTIQAECG-LAAV
Mvan_1126|M.vanbaalenii_PYR-1 KLGFDYQTVAALNPSIVYTNCYGYGRTGPYAARPAYDDTIQAECG-LAAV
MUL_1046|M.ulcerans_Agy99 GLGLDFAAVSDRNPRLVYGLITGYGETGPDADRAAYDVAAFWSRGGLAHL
MSMEG_2171|M.smegmatis_MC2_155 RLGFSEEVLQELNPRLIILSISGFGHDGPEAGRAGYDQIAQGEAGLMSLT
TH_4522|M.thermoresistible__bu RAGLDLEDLCERHEKLVALSISPFGLTGPWANYRTSDLVALAAGGLLNSC
*:. : : :: :* ** : * :
Mb1897|M.bovis_AF2122/97 WTSDEAQP--DNSRHPFYDATTIFPDHVVGRVGALLALAALIHRDRTGGG
Rv1866|M.tuberculosis_H37Rv WTSDEAQP--DNSRHPFYDATTIFPDHVVGRVGALLALAALIHRDRTGGG
MMAR_2745|M.marinum_M WTSEDAAT--DGSRHAFYDATTIFPDHVVGRIVAVLALAALIHRHRTGAG
MAV_2852|M.avium_104 WTSDDAREHDDDGRHAFYDATTIFPDHVVGRVTAIAALAALIHRDRAGAG
MAB_4651c|M.abscessus_ATCC_199 NGFPGGPP---------PRMALSIGDTLAGMFAAQGALAALYRRTVTGRG
Mflv_5186|M.gilvum_PYR-GCK QEELTGTAG---------YVGSIMADKICGLTAVNATMMALFHRERTGEG
Mvan_1126|M.vanbaalenii_PYR-1 QEELTGTAG---------YVGSIMADKVCGLSALNATMMALFHRARTGEG
MUL_1046|M.ulcerans_Agy99 LTRPGDTPP---------FQRGGMGDHTTGMTLAAAVCAAPLARERTGTG
MSMEG_2171|M.smegmatis_MC2_155 GANPHDLQR----------VGVPIADLLAGMYGAFGVLAALNERARTGRG
TH_4522|M.thermoresistible__bu GYDDHSIPP--------IRPGGNQAYMTAASFALCGVTLALIERQATGRG
. . * * :* *
Mb1897|M.bovis_AF2122/97 --AHVHISQAEVVVNQLDTMFVAEAARATDVAEIHPDTSVHAV--YPCAG
Rv1866|M.tuberculosis_H37Rv --AHVHISQAEVVVNQLDTMFVAEAARATDVAEIHPDTSVHAV--YPCAG
MMAR_2745|M.marinum_M --AHVHISQAEVVVNQLDTLFVTEAALAAGIAEVRNDLSVHAV--CPCAG
MAV_2852|M.avium_104 --AHVHISQAEVVVNQLDTLYVTQAALAAGVAQIRPDTGLHAV--YPCAG
MAB_4651c|M.abscessus_ATCC_199 QVVDAALTESCLAVQESTIPDYDVGRVVRGPSGTRLEGIAPSN--IYQSA
Mflv_5186|M.gilvum_PYR-GCK QEVEVPMFETMAAFMLVEHANGAMFDPPLGPALYPRTVARNRR--PYQTS
Mvan_1126|M.vanbaalenii_PYR-1 QEVEVPMFETMAAFMLVEHANGAMFDPPLGPALYPRTVARNRR--PYPTL
MUL_1046|M.ulcerans_Agy99 QLVSTSLYRQGAYTVSFDLNTYLLTGQQIAIGQRESMGNPCMN--NYTAG
MSMEG_2171|M.smegmatis_MC2_155 QVVRASLLAAVVGVHAFQGTKWTVAGQIGEATGNHHPSICPYG--LFDTA
TH_4522|M.thermoresistible__bu QLVDVSIHEANAVTGELANPYWFYPKAIVKRQTCRHAQPLPTQPALFQCA
. . :
Mb1897|M.bovis_AF2122/97 DDE-WCVISIRSDD----EWRRATSVFGQPELANDPRFGASRSRVANRSE
Rv1866|M.tuberculosis_H37Rv DDE-WCVISIRSDD----EWRRATSVFGQPELANDPRFGASRSRVANRSE
MMAR_2745|M.marinum_M DDE-WCVVTICSDN----EWRCAAKLIDQPELADDPRFASAESRMANRAE
MAV_2852|M.avium_104 DDE-WCVISIRSDD----EWRRAAAVFDHAEWADDPRFGTAEARLAHRRE
MAB_4651c|M.abscessus_ATCC_199 DGS-WVVIAANQDT----VFRRLCEAMGRPELSSDARFANHVARGRNQDD
Mflv_5186|M.gilvum_PYR-GCK DG--HIAALIYNDK----QWQAFIDAVK-PAWATD-RYATMAGRAADIDT
Mvan_1126|M.vanbaalenii_PYR-1 DG--HIAVLIYNDK----QWHAFIDAVK-PAWASD-RYATMAGRAADIDT
MUL_1046|M.ulcerans_Agy99 DGRRFWIVGLEIDR----HWPALCRVVERPDWLADPRYGDARGRATNAVE
MSMEG_2171|M.smegmatis_MC2_155 DGA--VQIAVGSEG----LWKRFCDGFHLDAHAPG--MATNPERVANQKR
TH_4522|M.thermoresistible__bu DGVWVYFALILADQHAWKALTSWMDEVGVAADLIEEEYLSLAHRQANFAH
*. : . * .
Mb1897|M.bovis_AF2122/97 LVAAVSAWTSTRTPVQAAGALQAAG-VAAGPMNRPSDILEDPQLIERNLF
Rv1866|M.tuberculosis_H37Rv LVAAVSAWTSTRTPVQAAGALQAAG-VAAGPMNRPSDILEDPQLIERNLF
MMAR_2745|M.marinum_M LVAVVSAWTADHTPFEAAQALQAAG-IAAGPMNRPPDLLEDPQLIARNLF
MAV_2852|M.avium_104 LVELVSAWTRTRTPVRAAELLQAAA-VPAGPMNRPPDILEDPQLIARNLY
MAB_4651c|M.abscessus_ATCC_199 LDAIIAQWAAQRLPTDIIDVLSAAG-VIAGPINTVADVVQDPQLKAREML
Mflv_5186|M.gilvum_PYR-GCK VYGLIGDALRERTTAEWLALFDELG-IPASPLRSTGDLFTDPHLDAVGFF
Mvan_1126|M.vanbaalenii_PYR-1 VYGLVGDTLREQTTADWLALFDKLG-IPASPLRTTDELFTDAHLEAVGFF
MUL_1046|M.ulcerans_Agy99 LIAQLDQIFATRSLAEWTEIFDAEPDFFWSPINSLEDIVADEQFHAAGGI
MSMEG_2171|M.smegmatis_MC2_155 VNDLVQNVFSLYSTDELLGILDQIG-VPAGRIRNLREVYEWEQTRSQGLL
TH_4522|M.thermoresistible__bu IQGLLEAFFMLQDSETVYRDGQRWG-LPIGPLRAPEEVLQDEHLKARNFF
: : . . . :. :: :
Mb1897|M.bovis_AF2122/97 RDMVHPLIARPLPAETGPAPFRHI-PQAPQRPAPL-PGQDSVQICRKLLG
Rv1866|M.tuberculosis_H37Rv RDMVHPLIARPLPAETGPAPFRHI-PQAPQRPAPL-PGQDSVQICRKLLG
MMAR_2745|M.marinum_M RDMTHPLIARPLPAETGPAPFRHI-PQSPQRPAPQ-PGQDTREICAELLD
MAV_2852|M.avium_104 RPMRHPLIDNPLPAETGPAPFRHI-PPARQAPAPL-PGQDTVAICRDLLG
MAB_4651c|M.abscessus_ATCC_199 VEHFDERLGRSVLGPGVVPVLSES-PGGVRNAGPARPGQDNDDVYVGLLG
Mflv_5186|M.gilvum_PYR-GCK ETVQTG--HGPVRFPGVPTGFSRT-PGRVRGGAPR-LGEHTAEVLADWGQ
Mvan_1126|M.vanbaalenii_PYR-1 ETVQTA--HGPVRFPGVPTGFSRT-PGRVRGGAPR-LGEHTAEVLAEVGI
MUL_1046|M.ulcerans_Agy99 VDVPDG--ASSVPMVATPADFHGT-PCTPRSVAPQ-LGQHTDQVLGELAA
MSMEG_2171|M.smegmatis_MC2_155 IDVDHATLGKITLPGPPLRFFDVAGPERTRRDHSAPPVLGADNHLIDELT
TH_4522|M.thermoresistible__bu VDVELAD-GSTATFPGLPYRFSNG---NGTPARPPLLGEHTDEVLSGV--
: .
Mb1897|M.bovis_AF2122/97 MTADETERLINERVMFGPAVTA--------------
Rv1866|M.tuberculosis_H37Rv MTADETERLINERVMFGPAVTA--------------
MMAR_2745|M.marinum_M MSPEEIEFLITEGVLFAPSANSEQLATEQQGSGESR
MAV_2852|M.avium_104 MNTADIRRLIDERVLFGPADPAGPAPGPTARPDS--
MAB_4651c|M.abscessus_ATCC_199 KSAQDIERLRAEGVL---------------------
Mflv_5186|M.gilvum_PYR-GCK EPVK--------------------------------
Mvan_1126|M.vanbaalenii_PYR-1 APPD--------------------------------
MUL_1046|M.ulcerans_Agy99 RRRS--------------------------------
MSMEG_2171|M.smegmatis_MC2_155 AGRR--------------------------------
TH_4522|M.thermoresistible__bu ------------------------------------