For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_4428 | - | - | 100% (278) | - |
M. thermoresistible (build 8) | TH_1455 | - | 6e-10 | 28.85% (104) | CBS domain protein |
M. thermoresistible (build 8) | TH_1679 | guaB2 | 3e-09 | 32.48% (117) | PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB2 (IMP |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2659c | - | 4e-13 | 33.90% (118) | hypothetical protein Mb2659c |
M. gilvum PYR-GCK | Mflv_2670 | - | 2e-11 | 28.57% (126) | signal-transduction protein |
M. tuberculosis H37Rv | Rv2626c | - | 5e-13 | 33.90% (118) | hypothetical protein Rv2626c |
M. leprae Br4923 | MLBr_00387 | guaB2 | 1e-11 | 31.16% (138) | inosine 5'-monophosphate dehydrogenase |
M. abscessus ATCC 19977 | MAB_3721c | - | 4e-08 | 31.62% (117) | inosine 5'-monophosphate dehydrogenase |
M. marinum M | MMAR_3726 | - | 3e-12 | 26.19% (126) | transcriptional regulator |
M. avium 104 | MAV_4356 | guaB | 2e-12 | 33.33% (138) | inositol-5-monophosphate dehydrogenase |
M. smegmatis MC2 155 | MSMEG_4564 | - | 7e-13 | 29.69% (128) | CBS domain-containing protein |
M. ulcerans Agy99 | MUL_3669 | - | 3e-12 | 26.19% (126) | transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_3907 | - | 5e-11 | 26.98% (126) | signal-transduction protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb2659c|M.bovis_AF2122/97 -------------------------------------------------- Rv2626c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2670|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3907|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3726|M.marinum_M -------------------------------------------------- MUL_3669|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_4564|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_00387|M.leprae_Br4923 MIRGMSNLKESSDFVASSYVRLGGLMDDPAATGGDNPHKVAMLGLTFDDV MAV_4356|M.avium_104 MTRGTSHLEDSSDLVGSAYVRVGGLVDDPVPTGGDNPHKIAMLGLTFDDV MAB_3721c|M.abscessus_ATCC_199 MT----------------------IAAGSVHTGGDDPHKVAMLGLTFDDV TH_4428|M.thermoresistible__bu -------------------------------------------------- Mb2659c|M.bovis_AF2122/97 ----------------------------------------MTTARDIMNA Rv2626c|M.tuberculosis_H37Rv ----------------------------------------MTTARDIMNA Mflv_2670|M.gilvum_PYR-GCK ----------------------------------------MRISDVLRSK Mvan_3907|M.vanbaalenii_PYR-1 ----------------------------------------MRISDVLRNK MMAR_3726|M.marinum_M ----------------------------------------MRIADVLRNK MUL_3669|M.ulcerans_Agy99 ----------------------------------------MRIADVLRNK MSMEG_4564|M.smegmatis_MC2_155 ----------------------------------------MRIADVLKNK MLBr_00387|M.leprae_Br4923 LLLPAASDVVPATADISSQLTKKIRLKVPLVSSAMDTVTEARMAIAMARA MAV_4356|M.avium_104 LLLPAASDVVPATADTSSQLTKKIRLKVPLVSSAMDTVTESRMAIAMARA MAB_3721c|M.abscessus_ATCC_199 LLLPAASDVLPAGADTSSQLTKRIRLNVPLVSSAMDTVTEARMAIAMARA TH_4428|M.thermoresistible__bu -------------------------------------------------- Mb2659c|M.bovis_AF2122/97 G-------------------------------VTCVGEHETLTAAAQYMR Rv2626c|M.tuberculosis_H37Rv G-------------------------------VTCVGEHETLTAAAQYMR Mflv_2670|M.gilvum_PYR-GCK GAA-----------------------------VATITPETSVAGLLTELS Mvan_3907|M.vanbaalenii_PYR-1 GAT-----------------------------VATITPETSVAGLLTELS MMAR_3726|M.marinum_M GAA-----------------------------VTTINPDATVRELLAGLA MUL_3669|M.ulcerans_Agy99 GAV-----------------------------VTTINPDATVRELFAGLA MSMEG_4564|M.smegmatis_MC2_155 GTA-----------------------------VVTISPQATVTELLAGLA MLBr_00387|M.leprae_Br4923 GGMGVLHRNLPVGEQAGQVETVKRSEAGMVTDPVTCRPDNTLAQVGALCA MAV_4356|M.avium_104 GGMGVLHRNLPVAEQAGQVEMVKRSEAGMVTDPVTCRPDNTLAQVDALCA MAB_3721c|M.abscessus_ATCC_199 GGMGVLHRNLSVEDQAGQVETVKRSEAGMVTNPVTCSPANTLAEVDALCA TH_4428|M.thermoresistible__bu ---------------------------------VVLNPNDPILEAARAIE . .: Mb2659c|M.bovis_AF2122/97 EHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELARDSIY Rv2626c|M.tuberculosis_H37Rv EHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELARDSIY Mflv_2670|M.gilvum_PYR-GCK VRNIGAMVVVSPDG-LQGIVSERDIVRKLHDMGADLLRRPVSEIMTTLVA Mvan_3907|M.vanbaalenii_PYR-1 VHNIGAMVVVSPDG-LLGIVSERDVVRKLHDMGADLLRRPVSEIMSTLVA MMAR_3726|M.marinum_M EQNIGAMVVVGVEG-VVGIVSERDVVRQLHTHGASVLTRPVSKIMTSAVA MUL_3669|M.ulcerans_Agy99 EQNIGAMVVVGVEG-VVGIVSERDVVRQLHTHGASVLTRPVSKIMTSAVA MSMEG_4564|M.smegmatis_MC2_155 EMNIGAMVVMGKSG-LEGIVSERDVVRQLHKRGSSLLAQPVSSIMTSVVA MLBr_00387|M.leprae_Br4923 RFRISGLPVVDDSGALAGIITNRDMR-----FEVDQSKQVAEVMTKTPLI MAV_4356|M.avium_104 RFRISGLPVVDDSGALVGIITNRDMR-----FEVDQTKKVAEVMTKAPLI MAB_3721c|M.abscessus_ATCC_199 RFRISGLPVVDAQGALVGIITNRDMR-----FEADLSKPVAEVMTKAPLI TH_4428|M.thermoresistible__bu ENRIGAVVIQ-KGGRLVGIVTDRDLAVRALGRGLDPNTTKIAEVMTESPI *..: : . : *::::**: . : Mb2659c|M.bovis_AF2122/97 YVDANASIQEMLNVMEEHQVRRVPVISE-HRLVGIVTEADIARHLPEHAI Rv2626c|M.tuberculosis_H37Rv YVDANASIQEMLNVMEEHQVRRVPVISE-HRLVGIVTEADIARHLPEHAI Mflv_2670|M.gilvum_PYR-GCK TCTPDDSVDSLSALMTNNRVRHVPVVVD-GRLAGIVSIGDVVKTR-MEEL Mvan_3907|M.vanbaalenii_PYR-1 TCTPDDTVDSLSALMTNNRVRHVPVVVD-GRLAGIVSIGDVVKTR-MEEL MMAR_3726|M.marinum_M TCTKSDTVDSISVLMTQNRVRHVPVLDG-QKLIGIVSIGDVVKSR-MGEL MUL_3669|M.ulcerans_Agy99 TCTKSDTVDSISVLMTQNRVRHVPVLDG-QKLIGIVSIGDVVKSR-MGEL MSMEG_4564|M.smegmatis_MC2_155 TCTPRDTVDRLNVLMTQNRVRHIPVLDD-GRLAGIVSIGDVVKTR-MEEL MLBr_00387|M.leprae_Br4923 TAAEGVSADAALGLLRRNKIEKLPVVDGHGRLTGLITVKDFVKTEQHPLA MAV_4356|M.avium_104 TAQEGVSADAALGLLRRNKIEKLPIVDGHGRLTGLITVKDFVKTEQHPLA MAB_3721c|M.abscessus_ATCC_199 TAREGVTADAALGLLRRNKIEKLPIVDGEGRLTGLITVKDFAKTEQHPNA TH_4428|M.thermoresistible__bu TLTPRDSTDDAIRLMRERNIRRIPLVEH-DRVVGMVTLDDLILDEAAPLE : : :: ...:.::*:: :: *::: *. Mb2659c|M.bovis_AF2122/97 VQFVKA---ICSPMALAS-------------------------------- Rv2626c|M.tuberculosis_H37Rv VQFVKA---ICSPMALAS-------------------------------- Mflv_2670|M.gilvum_PYR-GCK EHEHER---LQAYITQG--------------------------------- Mvan_3907|M.vanbaalenii_PYR-1 EREQQH---LQAYITQG--------------------------------- MMAR_3726|M.marinum_M EAEQEQ---LQSYITQG--------------------------------- MUL_3669|M.ulcerans_Agy99 EAEQEQ---LQSYITQG--------------------------------- MSMEG_4564|M.smegmatis_MC2_155 ETEQQQ---LQAYITQGR-------------------------------- MLBr_00387|M.leprae_Br4923 TKDNDGRLLVGAAVGVGGDAWVRAMMLVDAGVDVLIVDTAHAHNRLVLDM MAV_4356|M.avium_104 TKDSDGRLLVGAAVGVGGDAWVRAMMLVDAGVDVLVVDTAHAHNRLVLDM MAB_3721c|M.abscessus_ATCC_199 TKDSDGRLLVGAAVGVGEDAWTRAMSLVDAGVDVLIVDTAHAHNRKVLDM TH_4428|M.thermoresistible__bu ELAAIVEAQIGEGGPADS-------------------DRSPARRRRLVRA : Mb2659c|M.bovis_AF2122/97 -------------------------------------------------- Rv2626c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2670|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3907|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3726|M.marinum_M -------------------------------------------------- MUL_3669|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_4564|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_00387|M.leprae_Br4923 VGKLKVEIGDRVQVIGGNVATRSAAAALVEAGADAVKVGVGPGSTCTTRV MAV_4356|M.avium_104 VGKLKAEVGERVEVIGGNVATRAAAAALVAAGADAVKVGVGPGSICTTRV MAB_3721c|M.abscessus_ATCC_199 VGKLKAEVGERVDVVGGNVATRSAAAALVEAGADAVKVGVGPGSICTTRV TH_4428|M.thermoresistible__bu EATLNRLVKQVQEDAGLEDADQARAALDIVVGALVRRLTPGEAKDFISQL Mb2659c|M.bovis_AF2122/97 -------------------------------------------------- Rv2626c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2670|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3907|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3726|M.marinum_M -------------------------------------------------- MUL_3669|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_4564|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_00387|M.leprae_Br4923 VAGVGAPQITAILEAVAACGPAGVPVIADGGLQYSGDIAKALAAGASTTM MAV_4356|M.avium_104 VAGVGAPQITAILEAVAACGPAGVPVIADGGLQYSGDIAKALAAGASTAM MAB_3721c|M.abscessus_ATCC_199 VAGVGAPQITAILEAATVCHPAGVPVIADGGMQYSGDIAKALAAGASTTM TH_4428|M.thermoresistible__bu PSLLKPHLQTLPPGPDRSVTRESIEGDLVARLGVDQSRATSVLASVANTV Mb2659c|M.bovis_AF2122/97 -------------------------------------------------- Rv2626c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2670|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3907|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3726|M.marinum_M -------------------------------------------------- MUL_3669|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_4564|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_00387|M.leprae_Br4923 LGSLLAGTAEAPGELIFVNGKQFKSYRGMGSLGAMQGRG--GDKSYSKDR MAV_4356|M.avium_104 LGSLLAGTAEAPGELIFVNGKQFKSYRGMGSLGAMAGRGSGAGKSYSKDR MAB_3721c|M.abscessus_ATCC_199 LGSLLAGTAESPGELIFVNGKQFKSYRGMGSMGAMQGRG--ATKSYSKDR TH_4428|M.thermoresistible__bu LDSISPGEADEVRRQLPKELQDVLAAPAAGS------------------- Mb2659c|M.bovis_AF2122/97 -------------------------------------------------- Rv2626c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_2670|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3907|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3726|M.marinum_M -------------------------------------------------- MUL_3669|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_4564|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_00387|M.leprae_Br4923 YFADDALSEDKLVPEGIEGRVPFRGPLSSVIHQLVGGLRAAMGYTGSPTI MAV_4356|M.avium_104 YFADDALSEDKLVPEGIEGRVPFRGPLSSVIHQLTGGLRAAMGYTGSPTI MAB_3721c|M.abscessus_ATCC_199 YFQDDVLSEDKLVPEGIEGRVPFRGPLSTVMHQLTGGLRAAMGYTGASSI TH_4428|M.thermoresistible__bu -------------------------------------------------- Mb2659c|M.bovis_AF2122/97 ------------------------------------ Rv2626c|M.tuberculosis_H37Rv ------------------------------------ Mflv_2670|M.gilvum_PYR-GCK ------------------------------------ Mvan_3907|M.vanbaalenii_PYR-1 ------------------------------------ MMAR_3726|M.marinum_M ------------------------------------ MUL_3669|M.ulcerans_Agy99 ------------------------------------ MSMEG_4564|M.smegmatis_MC2_155 ------------------------------------ MLBr_00387|M.leprae_Br4923 EVLQQAQFVRITPAGLKESHPHDVAMTVEAPNYYPR MAV_4356|M.avium_104 EALQQAQFVRITAAGLRESHPHDVAMTVEAPNYYAR MAB_3721c|M.abscessus_ATCC_199 EELQRAQFVQITAAGLKESHPHDITMTAEAPNYYVR TH_4428|M.thermoresistible__bu ------------------------------------