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M. thermoresistible (build 8) TH_4428 (-)

annotation: -
coordinates: 298420 - 299253
length: 278

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4428--100% (278)-
M. thermoresistible (build 8)TH_1455-6e-1028.85% (104) CBS domain protein
M. thermoresistible (build 8)TH_1679guaB23e-0932.48% (117) PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB2 (IMP

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2659c-4e-1333.90% (118) hypothetical protein Mb2659c
M. gilvum PYR-GCKMflv_2670-2e-1128.57% (126) signal-transduction protein
M. tuberculosis H37RvRv2626c-5e-1333.90% (118) hypothetical protein Rv2626c
M. leprae Br4923MLBr_00387guaB21e-1131.16% (138) inosine 5'-monophosphate dehydrogenase
M. abscessus ATCC 19977MAB_3721c-4e-0831.62% (117) inosine 5'-monophosphate dehydrogenase
M. marinum MMMAR_3726-3e-1226.19% (126) transcriptional regulator
M. avium 104MAV_4356guaB2e-1233.33% (138) inositol-5-monophosphate dehydrogenase
M. smegmatis MC2 155MSMEG_4564-7e-1329.69% (128) CBS domain-containing protein
M. ulcerans Agy99MUL_3669-3e-1226.19% (126) transcriptional regulator
M. vanbaalenii PYR-1Mvan_3907-5e-1126.98% (126) signal-transduction protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2659c|M.bovis_AF2122/97           --------------------------------------------------
Rv2626c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_2670|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3726|M.marinum_M               --------------------------------------------------
MUL_3669|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4564|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_00387|M.leprae_Br4923          MIRGMSNLKESSDFVASSYVRLGGLMDDPAATGGDNPHKVAMLGLTFDDV
MAV_4356|M.avium_104                MTRGTSHLEDSSDLVGSAYVRVGGLVDDPVPTGGDNPHKIAMLGLTFDDV
MAB_3721c|M.abscessus_ATCC_199      MT----------------------IAAGSVHTGGDDPHKVAMLGLTFDDV
TH_4428|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2659c|M.bovis_AF2122/97           ----------------------------------------MTTARDIMNA
Rv2626c|M.tuberculosis_H37Rv        ----------------------------------------MTTARDIMNA
Mflv_2670|M.gilvum_PYR-GCK          ----------------------------------------MRISDVLRSK
Mvan_3907|M.vanbaalenii_PYR-1       ----------------------------------------MRISDVLRNK
MMAR_3726|M.marinum_M               ----------------------------------------MRIADVLRNK
MUL_3669|M.ulcerans_Agy99           ----------------------------------------MRIADVLRNK
MSMEG_4564|M.smegmatis_MC2_155      ----------------------------------------MRIADVLKNK
MLBr_00387|M.leprae_Br4923          LLLPAASDVVPATADISSQLTKKIRLKVPLVSSAMDTVTEARMAIAMARA
MAV_4356|M.avium_104                LLLPAASDVVPATADTSSQLTKKIRLKVPLVSSAMDTVTESRMAIAMARA
MAB_3721c|M.abscessus_ATCC_199      LLLPAASDVLPAGADTSSQLTKRIRLNVPLVSSAMDTVTEARMAIAMARA
TH_4428|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2659c|M.bovis_AF2122/97           G-------------------------------VTCVGEHETLTAAAQYMR
Rv2626c|M.tuberculosis_H37Rv        G-------------------------------VTCVGEHETLTAAAQYMR
Mflv_2670|M.gilvum_PYR-GCK          GAA-----------------------------VATITPETSVAGLLTELS
Mvan_3907|M.vanbaalenii_PYR-1       GAT-----------------------------VATITPETSVAGLLTELS
MMAR_3726|M.marinum_M               GAA-----------------------------VTTINPDATVRELLAGLA
MUL_3669|M.ulcerans_Agy99           GAV-----------------------------VTTINPDATVRELFAGLA
MSMEG_4564|M.smegmatis_MC2_155      GTA-----------------------------VVTISPQATVTELLAGLA
MLBr_00387|M.leprae_Br4923          GGMGVLHRNLPVGEQAGQVETVKRSEAGMVTDPVTCRPDNTLAQVGALCA
MAV_4356|M.avium_104                GGMGVLHRNLPVAEQAGQVEMVKRSEAGMVTDPVTCRPDNTLAQVDALCA
MAB_3721c|M.abscessus_ATCC_199      GGMGVLHRNLSVEDQAGQVETVKRSEAGMVTNPVTCSPANTLAEVDALCA
TH_4428|M.thermoresistible__bu      ---------------------------------VVLNPNDPILEAARAIE
                                                                     .      .:        

Mb2659c|M.bovis_AF2122/97           EHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELARDSIY
Rv2626c|M.tuberculosis_H37Rv        EHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELARDSIY
Mflv_2670|M.gilvum_PYR-GCK          VRNIGAMVVVSPDG-LQGIVSERDIVRKLHDMGADLLRRPVSEIMTTLVA
Mvan_3907|M.vanbaalenii_PYR-1       VHNIGAMVVVSPDG-LLGIVSERDVVRKLHDMGADLLRRPVSEIMSTLVA
MMAR_3726|M.marinum_M               EQNIGAMVVVGVEG-VVGIVSERDVVRQLHTHGASVLTRPVSKIMTSAVA
MUL_3669|M.ulcerans_Agy99           EQNIGAMVVVGVEG-VVGIVSERDVVRQLHTHGASVLTRPVSKIMTSAVA
MSMEG_4564|M.smegmatis_MC2_155      EMNIGAMVVMGKSG-LEGIVSERDVVRQLHKRGSSLLAQPVSSIMTSVVA
MLBr_00387|M.leprae_Br4923          RFRISGLPVVDDSGALAGIITNRDMR-----FEVDQSKQVAEVMTKTPLI
MAV_4356|M.avium_104                RFRISGLPVVDDSGALVGIITNRDMR-----FEVDQTKKVAEVMTKAPLI
MAB_3721c|M.abscessus_ATCC_199      RFRISGLPVVDAQGALVGIITNRDMR-----FEADLSKPVAEVMTKAPLI
TH_4428|M.thermoresistible__bu      ENRIGAVVIQ-KGGRLVGIVTDRDLAVRALGRGLDPNTTKIAEVMTESPI
                                       *..: :    . : *::::**:         .        :      

Mb2659c|M.bovis_AF2122/97           YVDANASIQEMLNVMEEHQVRRVPVISE-HRLVGIVTEADIARHLPEHAI
Rv2626c|M.tuberculosis_H37Rv        YVDANASIQEMLNVMEEHQVRRVPVISE-HRLVGIVTEADIARHLPEHAI
Mflv_2670|M.gilvum_PYR-GCK          TCTPDDSVDSLSALMTNNRVRHVPVVVD-GRLAGIVSIGDVVKTR-MEEL
Mvan_3907|M.vanbaalenii_PYR-1       TCTPDDTVDSLSALMTNNRVRHVPVVVD-GRLAGIVSIGDVVKTR-MEEL
MMAR_3726|M.marinum_M               TCTKSDTVDSISVLMTQNRVRHVPVLDG-QKLIGIVSIGDVVKSR-MGEL
MUL_3669|M.ulcerans_Agy99           TCTKSDTVDSISVLMTQNRVRHVPVLDG-QKLIGIVSIGDVVKSR-MGEL
MSMEG_4564|M.smegmatis_MC2_155      TCTPRDTVDRLNVLMTQNRVRHIPVLDD-GRLAGIVSIGDVVKTR-MEEL
MLBr_00387|M.leprae_Br4923          TAAEGVSADAALGLLRRNKIEKLPVVDGHGRLTGLITVKDFVKTEQHPLA
MAV_4356|M.avium_104                TAQEGVSADAALGLLRRNKIEKLPIVDGHGRLTGLITVKDFVKTEQHPLA
MAB_3721c|M.abscessus_ATCC_199      TAREGVTADAALGLLRRNKIEKLPIVDGEGRLTGLITVKDFAKTEQHPNA
TH_4428|M.thermoresistible__bu      TLTPRDSTDDAIRLMRERNIRRIPLVEH-DRVVGMVTLDDLILDEAAPLE
                                          : :    :: ...:.::*::    :: *:::  *.         

Mb2659c|M.bovis_AF2122/97           VQFVKA---ICSPMALAS--------------------------------
Rv2626c|M.tuberculosis_H37Rv        VQFVKA---ICSPMALAS--------------------------------
Mflv_2670|M.gilvum_PYR-GCK          EHEHER---LQAYITQG---------------------------------
Mvan_3907|M.vanbaalenii_PYR-1       EREQQH---LQAYITQG---------------------------------
MMAR_3726|M.marinum_M               EAEQEQ---LQSYITQG---------------------------------
MUL_3669|M.ulcerans_Agy99           EAEQEQ---LQSYITQG---------------------------------
MSMEG_4564|M.smegmatis_MC2_155      ETEQQQ---LQAYITQGR--------------------------------
MLBr_00387|M.leprae_Br4923          TKDNDGRLLVGAAVGVGGDAWVRAMMLVDAGVDVLIVDTAHAHNRLVLDM
MAV_4356|M.avium_104                TKDSDGRLLVGAAVGVGGDAWVRAMMLVDAGVDVLVVDTAHAHNRLVLDM
MAB_3721c|M.abscessus_ATCC_199      TKDSDGRLLVGAAVGVGEDAWTRAMSLVDAGVDVLIVDTAHAHNRKVLDM
TH_4428|M.thermoresistible__bu      ELAAIVEAQIGEGGPADS-------------------DRSPARRRRLVRA
                                             :                                        

Mb2659c|M.bovis_AF2122/97           --------------------------------------------------
Rv2626c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_2670|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3726|M.marinum_M               --------------------------------------------------
MUL_3669|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4564|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_00387|M.leprae_Br4923          VGKLKVEIGDRVQVIGGNVATRSAAAALVEAGADAVKVGVGPGSTCTTRV
MAV_4356|M.avium_104                VGKLKAEVGERVEVIGGNVATRAAAAALVAAGADAVKVGVGPGSICTTRV
MAB_3721c|M.abscessus_ATCC_199      VGKLKAEVGERVDVVGGNVATRSAAAALVEAGADAVKVGVGPGSICTTRV
TH_4428|M.thermoresistible__bu      EATLNRLVKQVQEDAGLEDADQARAALDIVVGALVRRLTPGEAKDFISQL
                                                                                      

Mb2659c|M.bovis_AF2122/97           --------------------------------------------------
Rv2626c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_2670|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3726|M.marinum_M               --------------------------------------------------
MUL_3669|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4564|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_00387|M.leprae_Br4923          VAGVGAPQITAILEAVAACGPAGVPVIADGGLQYSGDIAKALAAGASTTM
MAV_4356|M.avium_104                VAGVGAPQITAILEAVAACGPAGVPVIADGGLQYSGDIAKALAAGASTAM
MAB_3721c|M.abscessus_ATCC_199      VAGVGAPQITAILEAATVCHPAGVPVIADGGMQYSGDIAKALAAGASTTM
TH_4428|M.thermoresistible__bu      PSLLKPHLQTLPPGPDRSVTRESIEGDLVARLGVDQSRATSVLASVANTV
                                                                                      

Mb2659c|M.bovis_AF2122/97           --------------------------------------------------
Rv2626c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_2670|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3726|M.marinum_M               --------------------------------------------------
MUL_3669|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4564|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_00387|M.leprae_Br4923          LGSLLAGTAEAPGELIFVNGKQFKSYRGMGSLGAMQGRG--GDKSYSKDR
MAV_4356|M.avium_104                LGSLLAGTAEAPGELIFVNGKQFKSYRGMGSLGAMAGRGSGAGKSYSKDR
MAB_3721c|M.abscessus_ATCC_199      LGSLLAGTAESPGELIFVNGKQFKSYRGMGSMGAMQGRG--ATKSYSKDR
TH_4428|M.thermoresistible__bu      LDSISPGEADEVRRQLPKELQDVLAAPAAGS-------------------
                                                                                      

Mb2659c|M.bovis_AF2122/97           --------------------------------------------------
Rv2626c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_2670|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3726|M.marinum_M               --------------------------------------------------
MUL_3669|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4564|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_00387|M.leprae_Br4923          YFADDALSEDKLVPEGIEGRVPFRGPLSSVIHQLVGGLRAAMGYTGSPTI
MAV_4356|M.avium_104                YFADDALSEDKLVPEGIEGRVPFRGPLSSVIHQLTGGLRAAMGYTGSPTI
MAB_3721c|M.abscessus_ATCC_199      YFQDDVLSEDKLVPEGIEGRVPFRGPLSTVMHQLTGGLRAAMGYTGASSI
TH_4428|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2659c|M.bovis_AF2122/97           ------------------------------------
Rv2626c|M.tuberculosis_H37Rv        ------------------------------------
Mflv_2670|M.gilvum_PYR-GCK          ------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1       ------------------------------------
MMAR_3726|M.marinum_M               ------------------------------------
MUL_3669|M.ulcerans_Agy99           ------------------------------------
MSMEG_4564|M.smegmatis_MC2_155      ------------------------------------
MLBr_00387|M.leprae_Br4923          EVLQQAQFVRITPAGLKESHPHDVAMTVEAPNYYPR
MAV_4356|M.avium_104                EALQQAQFVRITAAGLRESHPHDVAMTVEAPNYYAR
MAB_3721c|M.abscessus_ATCC_199      EELQRAQFVQITAAGLKESHPHDITMTAEAPNYYVR
TH_4428|M.thermoresistible__bu      ------------------------------------