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M. thermoresistible (build 8) TH_4308 (-)

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4308	-	-	100% (264)	putative putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_4102	-	3e-31	28.91% (256)	PUTATIVE short chain enoyl-CoA hydratase
M. thermoresistible (build 8)	TH_4028	-	6e-31	33.08% (260)	PUTATIVE Enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb1099c	echA8	2e-33	29.96% (257)	enoyl-CoA hydratase
M. gilvum PYR-GCK	Mflv_2036	-	6e-30	28.12% (256)	enoyl-CoA hydratase
M. tuberculosis H37Rv	Rv1070c	echA8	2e-33	29.96% (257)	enoyl-CoA hydratase
M. leprae Br4923	MLBr_02402	-	5e-30	29.07% (258)	enoyl-CoA hydratase
M. abscessus ATCC 19977	MAB_4588c	-	9e-31	31.40% (258)	enoyl-CoA hydratase/isomerase
M. marinum M	MMAR_4396	echA8	7e-33	30.86% (256)	enoyl-CoA hydratase EchA8
M. avium 104	MAV_5087	-	5e-31	31.71% (246)	enoyl-CoA hydratase/isomerase family protein
M. smegmatis MC2 155	MSMEG_5277	-	8e-29	28.46% (260)	enoyl-CoA hydratase
M. ulcerans Agy99	MUL_0210	echA8	5e-33	30.86% (256)	enoyl-CoA hydratase
M. vanbaalenii PYR-1	Mvan_4681	-	7e-30	28.91% (256)	enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4396|M.marinum_M               ---MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELDNDP
MUL_0210|M.ulcerans_Agy99           ---MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELDNDP
Mb1099c|M.bovis_AF2122/97           ---MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDP
Rv1070c|M.tuberculosis_H37Rv        ---MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDP
MLBr_02402|M.leprae_Br4923          ---MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDIDP
Mflv_2036|M.gilvum_PYR-GCK          ---MTFETILVDRDDRVATITLNRPKALNALNTQVMNEVTTAAAELDAEP
Mvan_4681|M.vanbaalenii_PYR-1       MGSQNFETIIVERDDRVATITLNRPKALNALNSQVMDEVTTAAAELDADA
MSMEG_5277|M.smegmatis_MC2_155      --MSDFETILVTRTDRVATIQLNRPKALNALNSQVMTEVTAAAAELDKDP
MAB_4588c|M.abscessus_ATCC_199      ----MADEVLIEQRDRVLLITINRPDARNAVNRAVSQGLAAAADQLDSSA
TH_4308|M.thermoresistible__bu      -MAIDTDHIVLEKDGQVARVWLNRPHKLNAVTPELLYRLDEIIVEVDNDP
MAV_5087|M.avium_104                -----MSEVVCTLDGAIGRITLNRPDRMNAINIAIADKLKVAVRTYGNHP
                                          . ::      :  : :***.  **:.  :   :       .  .

MMAR_4396|M.marinum_M               GIGAIIITGSAKAFAAGADIKEMADLTFSEAFDA-DFFAAWG----KLAA
MUL_0210|M.ulcerans_Agy99           GIGAIIITGSAKAFAAGADIKEMADLTFSEAFDA-DFFAAWG----KLAA
Mb1099c|M.bovis_AF2122/97           DIGAIIITGSAKAFAAGADIKEMADLTFADAFTA-DFFATWG----KLAA
Rv1070c|M.tuberculosis_H37Rv        DIGAIIITGSAKAFAAGADIKEMADLTFADAFTA-DFFATWG----KLAA
MLBr_02402|M.leprae_Br4923          DVGAILITGSPKVFAAGADIKEMASLTFTDAFDA-DFFSAWG----KLAA
Mflv_2036|M.gilvum_PYR-GCK          GVGAIIVTGSERAFAAGADIKEMASLSFADVFSS-DFFAAWG----KFAA
Mvan_4681|M.vanbaalenii_PYR-1       GVGAIILTGSEKAFAAGADIKEMAGLSFADVFSS-DFFAGWG----KFAA
MSMEG_5277|M.smegmatis_MC2_155      GVGAIIVTGNEKAFAAGADIKEMADLSFAEVFEA-DFFELWS----KFAA
MAB_4588c|M.abscessus_ATCC_199      DLSVAIITGAGGNFCAGMDLKAFVS---GEAVLS-ERGLGFT----NVPP
TH_4308|M.thermoresistible__bu      DLRVLVLRGRGGTFCSGFDLDVLQADYVGSTTAM-DVAVLSAKVCDRLYS
MAV_5087|M.avium_104                DVHAIVIRGAGGNFCAGGDFTEVERLRAAGPAALRALFKTFHAACQAITD
                                    .: . :: *    *.:* *:  .                        .  

MMAR_4396|M.marinum_M               VRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGMGG
MUL_0210|M.ulcerans_Agy99           VRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGMGG
Mb1099c|M.bovis_AF2122/97           VRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGG
Rv1070c|M.tuberculosis_H37Rv        VRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGG
MLBr_02402|M.leprae_Br4923          VRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGG
Mflv_2036|M.gilvum_PYR-GCK          TRTPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVLPGMGG
Mvan_4681|M.vanbaalenii_PYR-1       TRTPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVLPGMGG
MSMEG_5277|M.smegmatis_MC2_155      TRTPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVLPGMGG
MAB_4588c|M.abscessus_ATCC_199      -RKPIIAAVEGFALAGGTELVLSCDLVVAGRSAKFGIPEVKRGLVAGAGG
TH_4308|M.thermoresistible__bu      MNTPSVAVLEGFVTAGGFELMISCDFALAAEDAKIGDFHIRRALFGGAGP
MAV_5087|M.avium_104                VDVPVVVAVEGVAMAGGFELMQAADIVLVSDNARIADNHINFGMIPGGGS
                                       * :..: * . .** *:   .*. :..  *::.  .:. .:. * * 

MMAR_4396|M.marinum_M               SQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAV
MUL_0210|M.ulcerans_Agy99           SQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAV
Mb1099c|M.bovis_AF2122/97           SQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARAT
Rv1070c|M.tuberculosis_H37Rv        SQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARAT
MLBr_02402|M.leprae_Br4923          SQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAV
Mflv_2036|M.gilvum_PYR-GCK          SQRLTRAIGKAKAMDLILTGRNMDAEEAERAGLVSRVVPADSLLSEAKAV
Mvan_4681|M.vanbaalenii_PYR-1       SQRLTRAIGKAKAMDLILTGRNMGAEEAERAGLVSRVVPADTLLEEARSV
MSMEG_5277|M.smegmatis_MC2_155      SQRLTRAIGKAKAMDLILTGRTIDAAEAERAGLVSRLVPADTLIDEALAV
MAB_4588c|M.abscessus_ATCC_199      LLRLPNRIPYQVAMELALTGESFTAEDAAKYGFINRLVDDGQALDTALEL
TH_4308|M.thermoresistible__bu      IYRLPRMIGIRKTKELMLTGKLLSGKEAEDFDLINASAPADQLDKLCEDF
MAV_5087|M.avium_104                TVRLPRNVGRQVALALMLSGERLSGADAVARGLAYRSFPAADFEDSVETF
                                      **.. :    :  * *:*. : . :*   .:                 

MMAR_4396|M.marinum_M               ATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAFATADQSEG
MUL_0210|M.ulcerans_Agy99           ATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAFATADQSEG
Mb1099c|M.bovis_AF2122/97           ATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEG
Rv1070c|M.tuberculosis_H37Rv        ATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEG
MLBr_02402|M.leprae_Br4923          ATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQSEG
Mflv_2036|M.gilvum_PYR-GCK          AQTIAGMSLSASRMAKEAVDRAFETTLSEGLLYERRLFHSAFATDDQTEG
Mvan_4681|M.vanbaalenii_PYR-1       AKTIAGMSLSASRMAKEAVDRAFETTLTEGLLYERRLFHSAFATDDQTEG
MSMEG_5277|M.smegmatis_MC2_155      AQTIAGMSLSASRMAKEAVNRAFETSLTEGLLYERRLFHSAFATADQKEG
MAB_4588c|M.abscessus_ATCC_199      AAKITANGPLAVAATKRIIIESASWAPEEAFAKQGEILMPIFVSEDAKEG
TH_4308|M.thermoresistible__bu      IAQLVDKSPFTMKLTKMCIDRGLDADIQSLMVMEHLAVGNALQSEDAKEG
MAV_5087|M.avium_104                VRQLAERDRGAATRIKRLVLDGLHRPIEEAVASETDAVVEWICGPAGSDG
                                       :   .  :    *  :         . .  :   .   :     .:*

MMAR_4396|M.marinum_M               MAAFIEKRPPNFTHR
MUL_0210|M.ulcerans_Agy99           MAAFIEKRPPNFTHR
Mb1099c|M.bovis_AF2122/97           MAAFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv        MAAFIEKRAPQFTHR
MLBr_02402|M.leprae_Br4923          MAAFIEKRAPQFTHR
Mflv_2036|M.gilvum_PYR-GCK          MNAFSEKRSPNFTHR
Mvan_4681|M.vanbaalenii_PYR-1       MNAFTEKRSPNFTHR
MSMEG_5277|M.smegmatis_MC2_155      MAAFAEKRAANFTHR
MAB_4588c|M.abscessus_ATCC_199      AKAFAEKRAPVWQGK
TH_4308|M.thermoresistible__bu      VAAFLEKREPKWVGR
MAV_5087|M.avium_104                VTAFQNREVAR----
                                      ** ::. .