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M. thermoresistible (build 8) TH_4268 (-)

annotation: putative monooxygenase
coordinates: 4700812 - 4702230
length: 473

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4268--100% (473)putative monooxygenase
M. thermoresistible (build 8)TH_4079-2e-6838.80% (415) PUTATIVE nitrilotriacetate monooxygenase component A
M. thermoresistible (build 8)TH_3119-1e-2026.20% (332) PUTATIVE putative Alkanesulfonate monooxygenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0815c-3e-0823.87% (243) hypothetical protein Mb0815c
M. gilvum PYR-GCKMflv_1269-2e-8938.51% (444) putative monooxygenase
M. tuberculosis H37RvRv0791c-3e-0823.87% (243) hypothetical protein Rv0791c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3401-0.084.96% (472) putative monooxygenase
M. marinum MMMAR_0703-8e-5332.85% (414) FMNH2-utilizing oxygenase
M. avium 104MAV_4059-1e-14557.21% (444) monoxygenase
M. smegmatis MC2 155MSMEG_4389-1e-15859.95% (442) monooxygenase, NtaA/SnaA/SoxA family protein
M. ulcerans Agy99MUL_3024-5e-0923.05% (243) oxidoreductase
M. vanbaalenii PYR-1Mvan_3887-6e-9840.65% (460) putative monooxygenase

CLUSTAL 2.0.9 multiple sequence alignment


TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4389|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4059|M.avium_104                MTLTSPAAASAGDLPARPGLRTVAAGSMIGTTIEWYDFYLYATASALVFK
Mflv_1269|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               --------------------------------------------------
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4389|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4059|M.avium_104                PLFFPNISPSAGTLASFATYAAGFGARPLGAVLSGHFGDRLGRKTVLVAA
Mflv_1269|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               --------------------------------------------------
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4389|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4059|M.avium_104                LLVMGLVTTAIGALPTYAEAGLAAPALLASLRVVQGLAVGAEWGGAAVLS
Mflv_1269|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               --------------------------------------------------
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4389|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4059|M.avium_104                VEHAPPGRRGLFGSFTQLGSPAGMLLATSVFFGVRKATGPAAFLGFGWRI
Mflv_1269|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               --------------------------------------------------
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4389|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4059|M.avium_104                PFLLSIFLVAVGLFVRLRLTDAEVFDRLRSRDELARLPIVQVLRTDARNV
Mflv_1269|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               --------------------------------------------------
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4389|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4059|M.avium_104                VITTGLRLSQIGLFVLLTTYSLSYLQDSFGKGSGVGLVAVLISSALGFLS
Mflv_1269|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               --------------------------------------------------
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4389|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4059|M.avium_104                TPGWALLSDRVGRRPPYLFGALASVVALVLFFVAAGTGSAVLVVVAIVFG
Mflv_1269|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               --------------------------------------------------
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_4389|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4059|M.avium_104                VNVVHDAMYGPQAAWFAELFDTRVRYSGSSLGYHIGAVLSGGFAPLIAAS
Mflv_1269|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               --------------------------------------------------
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --------------------------------------------------
MAB_3401|M.abscessus_ATCC_1997      -----------------------------------------MTRVIRFNA
MSMEG_4389|M.smegmatis_MC2_155      -----------------------------------------MTKQIILNA
MAV_4059|M.avium_104                LLVAGGGRPWLIVGYFAVLAAITVGAACAGPGDARGADRMSAARRIYLNA
Mflv_1269|M.gilvum_PYR-GCK          ----------------------------------MYSIQGMTQR-MIFTL
Mvan_3887|M.vanbaalenii_PYR-1       ----------------------------------------MTKRPLYYSA
Mb0815c|M.bovis_AF2122/97           ----------------------------------MNAKDDPHFGLMLAAT
Rv0791c|M.tuberculosis_H37Rv        ----------------------------------MNAKDDPHFGLMLAAT
MMAR_0703|M.marinum_M               ---------------------------------------------MIRKP
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      --MNCVAHQSPGLWKHPEDQSWRYKDLEYWTELARLLERGRFDGLFIADV
MAB_3401|M.abscessus_ATCC_1997      FDMNCVAHQSPGLWRHPDDQSWRYKDLSYWTNLATLLERGRFDGLFIADV
MSMEG_4389|M.smegmatis_MC2_155      FDMNCVTHIVAGTWRHPESQARRYKDIEYWTDLAKVLEKGLFDGLFIADV
MAV_4059|M.avium_104                FDMACVGHQSAGLWRHPDDQGHRYRELSYWTELARTLEAGGFDALFLADV
Mflv_1269|M.gilvum_PYR-GCK          LVMDSIGHNFHGSWRHPAARNREFKGFDMWVDLARKAEQAKVDAFFFTDV
Mvan_3887|M.vanbaalenii_PYR-1       FVMNTASHVLHGLWRAPDAQNHRFNSLRHWTSLAAEVDKAGYDVLFFADV
Mb0815c|M.bovis_AF2122/97           VNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFLTISPGEYAKVAGIAAD
Rv0791c|M.tuberculosis_H37Rv        VNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFLTISPGEYAKVAGIAAD
MMAR_0703|M.marinum_M               VHLAAHFPGVNNTTVWADPGAGSQIEFESFVHLARTAERGLFDFFFLAEG
MUL_3024|M.ulcerans_Agy99           -----MAIRLGFQIPSFSYGTGVDKLFPSVIAQAREAEAAGFDSLFLMDH
                                                              .               .   :   

TH_4268|M.thermoresistible__bu      LGTYDVYGAGDEAAIRQAAQIPVNDPMMLVSAMALVTEHLGFGITTGT-G
MAB_3401|M.abscessus_ATCC_1997      LGTYDIYGASDEAAIRQAAQIPVADPLLLVSAMALVTEHLGFGVTTGT-G
MSMEG_4389|M.smegmatis_MC2_155      LGIYDVFGGGPETALRTGAQVPVNDPLLVVPAMAAVTKHLGFGVTAAT-S
MAV_4059|M.avium_104                LGVYDIYGASRDAAVVDAAQFPVNEPSAAVSAMAAVTETLGFGITLSL-T
Mflv_1269|M.gilvum_PYR-GCK          MGVQGEYNGKRDIVFEMAMNVPIGDCTMLIPALAQQTRDLGFLYTSSV-I
Mvan_3887|M.vanbaalenii_PYR-1       FGLRAPWNGNWRKAVEGGIQVPVNDPSVLASAIAAATENLGIVFTSSI-V
Mb0815c|M.bovis_AF2122/97           TGSATGTETGGAGQCAPSRSLPLLECWTALAALSRDTTKLRLGTSVLCNS
Rv0791c|M.tuberculosis_H37Rv        TGSATGTETGGAGQCAPSRSLPLLECWTALAALSRDTTKLRLGTSVLCNS
MMAR_0703|M.marinum_M               LRLREHRGRIHDLDVVGRP-----DTFTLLAALAGVTDRIGLTGTINT-T
MUL_3024|M.ulcerans_Agy99           FYQLPMLG---------TPDQPMLEAYTALGALATATERLQLGTLVTGNT
                                                            :      *::  *  : :        

TH_4268|M.thermoresistible__bu      FEHPYPFARRMSTLDHLTKGRIGWNVVTGYLPAAARNMGQSDQPAHDARY
MAB_3401|M.abscessus_ATCC_1997      FEHPYPFARRLSTLDHLTGGRVGWNVVTGYLPAAARNMGQTDQPAHDARY
MSMEG_4389|M.smegmatis_MC2_155      FEHPYSFSRRMSTLDHLTKGRVGWNIVTGYLESAARNHGLDTITPHADRY
MAV_4059|M.avium_104                YEQPYALARRLSTLDHLTGGRVAWNIVTSYLDSAARNLGLDAQIPHDQRY
Mflv_1269|M.gilvum_PYR-GCK          SHHPFVFARAASTLDNLSNGRIGWNIVTSANEKAFRNLGLPGNLSHDERY
Mvan_3887|M.vanbaalenii_PYR-1       QDHPFNFARRMSSLDHYTDGRLGWNIVTSFNANMFRSFGHEGTLAHDQRY
Mb0815c|M.bovis_AF2122/97           YRHPSVLAKMAATLDVISQGRLDLGLGAGWFRRESQAYGIP-FPPVGDRV
Rv0791c|M.tuberculosis_H37Rv        YRHPSVLAKMAATLDVISQGRLDLGLGAGWFRRESQAYGIP-FPPVGDRV
MMAR_0703|M.marinum_M               FNEPFEVARQFATLDHLSEGRAGWNIVTSSDAFTGANFRRGGYLDHADRY
MUL_3024|M.ulcerans_Agy99           YRNPALLAKIITTLDVVSAGRAVLGIGAGWFELEHRQLGYE-FGTFTDRF
                                      .*  .::  ::**  : **   .: :.                   * 

TH_4268|M.thermoresistible__bu      DHADEYLEVLYKLWEGSWEDDAVIRDRERGVFTDPDKVHHIGHRGRHFSV
MAB_3401|M.abscessus_ATCC_1997      DHADEYLEVLYKLWEGSWEDDAVVRDAARGVFTDPDKVHHIGHEGTHFTV
MSMEG_4389|M.smegmatis_MC2_155      DIADEYTEVLYKLWEGSWEDDAVGADPNRAEYADAAKVHPINHEGTHFRV
MAV_4059|M.avium_104                EIADEYLEVCYKLWEGSWEAGAVLRDRQRGVFTDPAKVHDIEHKGRYFSV
Mflv_1269|M.gilvum_PYR-GCK          VWAQEYVDVTYKLWEGSWDVDAIVDDPASGVYADPSKVHDINHKGARYSV
Mvan_3887|M.vanbaalenii_PYR-1       EWANEYVDVTYKLWEGSWDDDALVQDKERSVHSDPSKIHKINHVGRRYTV
Mb0815c|M.bovis_AF2122/97           SALAESLQVIKAVWTE----------------------PNPTYAGRFYTL
Rv0791c|M.tuberculosis_H37Rv        SALAESLQVIKAVWTE----------------------PNPTYAGRFYTL
MMAR_0703|M.marinum_M               QRAEEFLTVARKFWDS-WAPGAVLADIENGDYVDPERIRSVEHSGPQFEV
MUL_3024|M.ulcerans_Agy99           NRLEEALQILDPIIKG----------------------ERPTFSGSWYQA
                                        *   :   .                             . *  :  

TH_4268|M.thermoresistible__bu      PGVHLSEPSPQR-TPVIYQAGSSPRGVRFAAENAEAIFTASPTKEILRRT
MAB_3401|M.abscessus_ATCC_1997      PGVHLVEPSPQR-TPVIYQAGSSPRGVRFAAENAEAVFTAAPTKELLRQT
MSMEG_4389|M.smegmatis_MC2_155      PGIHLCEPSPQR-TPVLYQAGASSRGRQFGAENAEVIFIGAPTKDVLREA
MAV_4059|M.avium_104                PGPFLCEPSPQR-TPVLFQAGASPRGIRFAAAHAEAVFVSGPTAQVVREP
Mflv_1269|M.gilvum_PYR-GCK          EGFNLMEPSPQR-TPVLAQAGGSPAGLAFAGKHAELMFLSAYSLETIAAQ
Mvan_3887|M.vanbaalenii_PYR-1       EGPHFTSPSPQR-TPVLFQAGSSPAGQLFSARNAEGVYISSPTPADAHKL
Mb0815c|M.bovis_AF2122/97           DGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSPQQVTQR
Rv0791c|M.tuberculosis_H37Rv        DGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSPQQVTQR
MMAR_0703|M.marinum_M               RGFATLPAGPQG-HPVLLQAGDSEQGRAFGARHADAMFTLHSSLRDGQRY
MUL_3024|M.ulcerans_Agy99           ESAMAEPRYRDR-IPILIGGGGEKKTFRIAAHWADHLNIVAA-LDELPRK
                                     .        :   * :  .*       :..  *: :             

TH_4268|M.thermoresistible__bu      VSTIRQELEIAGRDPYSVKIFNLTTIITAETDEEA-HARHAEYLAYGDPE
MAB_3401|M.abscessus_ATCC_1997      VTTIRRELELAGRDPYSAKIFNLTTVVTGENSEAA-HAKHAELLGYGSAE
MSMEG_4389|M.smegmatis_MC2_155      VADIRTRAAAAGRDPYDVKIVNSHVIVTGETESVA-QARYDEFRSYTDPQ
MAV_4059|M.avium_104                VRALRTAAAQLGRDPRAVKVFTMVTPVVAETHDAA-VAKLAEYRRFVSPR
Mflv_1269|M.gilvum_PYR-GCK          VGAVREQARTNGRRDGDILFLQGMMFVIGSTDEEA-YRKWGELEEWRSPE
Mvan_3887|M.vanbaalenii_PYR-1       TGETRALAAANGRDPQDITFAQGLSFVIGDTHAEA-VRRNDELKRYLDVE
Mb0815c|M.bovis_AF2122/97           RGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEE-VRIREEFASIPEPG
Rv0791c|M.tuberculosis_H37Rv        RGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEE-VRIREEFASIPEPG
MMAR_0703|M.marinum_M               YADVKGRARSYGRDPDQLKVFPAATFVIGDTPDQAGEKARQISYQQVSGA
MUL_3024|M.ulcerans_Agy99           MDAVAARCEEAGRDPSTLETSVMLTVVVDAKAKVERLPAETSRR------
                                               **                 .                   

TH_4268|M.thermoresistible__bu      GALTFMSGWMGVDLARYGLDEPVG---------NVDSNAILSAVAAFQSA
MAB_3401|M.abscessus_ATCC_1997      GALVFMSGWMGVDLARYGLDEPIG---------NVDSNAILSAVAAFQAA
MSMEG_4389|M.smegmatis_MC2_155      GALALWSGWLGTDLSRFDLDDPVE---------VTDNEFLKSSVEMFGQG
MAV_4059|M.avium_104                GALALFGGWTGVDLAELDPDEPLT---------YVETDANRSALASFTTA
Mflv_1269|M.gilvum_PYR-GCK          AQTAYFSSLSGMDLGRYDPGTPLENI-------LDEIPGIQGAFLAVINA
Mvan_3887|M.vanbaalenii_PYR-1       GVALHALGDAGIDAGNLPLDTPIS-A-------LGEFTGIQ-SFSRWAAE
Mb0815c|M.bovis_AF2122/97           --------------------------------------------------
Rv0791c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0703|M.marinum_M               TAIAMLEQVWGRDLSDYDPDGPLPDIDPIADAAISQGRVRHADPVAVARR
MUL_3024|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_4268|M.thermoresistible__bu      DPDGREWAVRDIAEWGKIGGMGPRIVGSGFTVADTLQEWVEETD-VDGFN
MAB_3401|M.abscessus_ATCC_1997      TADGREWKVRDIAEWGEIGGMGPRIVGSGTEVADTLQEWVEETD-VDGFN
MSMEG_4389|M.smegmatis_MC2_155      -----QWTLRDFIDAHAINVDGAMAVGSPQQVADDLQEWVEETD-VDGFN
MAV_4059|M.avium_104                G---RAWTVAELAAEIGIGGRGPVLVGSPTEVADELERWVDDAD-VDGFN
Mflv_1269|M.gilvum_PYR-GCK          WPDGSKPTIKDFLTSLSLPQ---MVVGSPETIAGRLLEYQGAG--VNGVQ
Mvan_3887|M.vanbaalenii_PYR-1       ISGNDEPTIRDMAWALEGAN---RVVGTPKEIADRLEEWREAG--VDGIN
Mb0815c|M.bovis_AF2122/97           -----------------------LIVGTPDRCVERIREYQDRGVGHFLFT
Rv0791c|M.tuberculosis_H37Rv        -----------------------LIVGTPDRCVERIREYQDRGVGHFLFT
MMAR_0703|M.marinum_M               YRERSQAENLSIRELVIAVTSRQQFVGTPSHIADEIDRYVQADA-CDGFI
MUL_3024|M.ulcerans_Agy99           -----------------------MVTGSPAQIADQVQTKVLDTG-IDGVI
                                                             .*:    .  :            . 

TH_4268|M.thermoresistible__bu      L---AYAITPGSFAQFIEHVVPVLTERGAYQPAYTPGTLRHKLFGKGDRL
MAB_3401|M.abscessus_ATCC_1997      L---AYAITPGTFEDFIEYVVPVLTERGAYQSSYTPGTLRHKLLGHGDRL
MSMEG_4389|M.smegmatis_MC2_155      L---TNVITPGTFVDVAEHVIPELQRRGAYKTEYTEGTLRHKLFGRGPRL
MAV_4059|M.avium_104                V---AYVTTPGTFVDFAKFVVPELRRRGHVPEQVPGSTLRERLGAAGPLL
Mflv_1269|M.gilvum_PYR-GCK          V---MNALLPNSYAEFFEHLVPVLQDKGIMQKEYQPGTLRQKLFGSGPDI
Mvan_3887|M.vanbaalenii_PYR-1       V---YHATLPASFREVADRLFPTLRERGLIGTD-KSGTLRHKLLGRGDRL
Mb0815c|M.bovis_AF2122/97           I---PHVVKSDYLHIIGSDIIPRVKTEVTIP-------------------
Rv0791c|M.tuberculosis_H37Rv        I---PHVVKSDYLHIIGSDIIPRVKTEVTIP-------------------
MMAR_0703|M.marinum_M               L---VPHLTPHGLDEFVDRVVPLLQERGAFRTAYTGQTLRDHLGLAGLPS
MUL_3024|M.ulcerans_Agy99           MNLSAHGHSPGLITTVAEALRPLLTG------------------------
                                    :        .     . . : * :                          

TH_4268|M.thermoresistible__bu      PDDHRGSRYRVGGPLSTIIDRPSTLPSSPASAASQPISGR
MAB_3401|M.abscessus_ATCC_1997      PEEHRGAKYRIGGPLSTIIDRPSTVPSSSGSTAPAPTPGR
MSMEG_4389|M.smegmatis_MC2_155      PETHRAANYRH---------------------VTQEVSA-
MAV_4059|M.avium_104                GDDHPGAAYRLRRDR-------------------------
Mflv_1269|M.gilvum_PYR-GCK          SERHPAHGYRGMFC--------------------------
Mvan_3887|M.vanbaalenii_PYR-1       PDTHPAARYRGAFSDNSLADRVPETVGSV-----------
Mb0815c|M.bovis_AF2122/97           ----------------------------------------
Rv0791c|M.tuberculosis_H37Rv        ----------------------------------------
MMAR_0703|M.marinum_M               ----------------------------------------
MUL_3024|M.ulcerans_Agy99           ----------------------------------------