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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_4175 | - | - | 100% (613) | linalool 8-monooxygenase |
M. thermoresistible (build 8) | TH_1956 | - | 4e-83 | 41.54% (402) | PROBABLE CYTOCHROME P450 125 CYP125 |
M. thermoresistible (build 8) | TH_3205 | - | 2e-81 | 41.48% (393) | PUTATIVE NikQ protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2289 | cyp124 | 1e-179 | 72.46% (414) | cytochrome P450 124 CYP124 |
M. gilvum PYR-GCK | Mflv_3307 | - | 0.0 | 74.94% (411) | cytochrome P450 |
M. tuberculosis H37Rv | Rv2266 | cyp124 | 1e-179 | 72.46% (414) | cytochrome P450 124 CYP124 |
M. leprae Br4923 | MLBr_02088 | - | 2e-38 | 30.72% (345) | putative cytochrome p450 |
M. abscessus ATCC 19977 | MAB_1211c | - | 2e-77 | 41.41% (384) | cytochrome P450 |
M. marinum M | MMAR_3361 | cyp124A1 | 1e-177 | 71.81% (415) | cytochrome P450 124A1, Cyp124A1 |
M. avium 104 | MAV_2174 | - | 1e-178 | 72.53% (415) | P450 heme-thiolate protein |
M. smegmatis MC2 155 | MSMEG_3551 | - | 0.0 | 78.90% (417) | linalool 8-monooxygenase |
M. ulcerans Agy99 | MUL_1282 | cyp124A1 | 1e-176 | 71.33% (415) | cytochrome P450 124A1, Cyp124A1 |
M. vanbaalenii PYR-1 | Mvan_3029 | - | 0.0 | 76.64% (411) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment Mb2289|M.bovis_AF2122/97 ----MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFATL Rv2266|M.tuberculosis_H37Rv ----MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFATL MMAR_3361|M.marinum_M MDLSTNLNTGLLPRVNGTPPPEVPLADIELGSLEFWGRDDDFRDGAFATL MUL_1282|M.ulcerans_Agy99 MDLSTNLNTGLLPRVNGTPPPEVPLADIELGSLEFWGRDDDFRDGAFATL MAV_2174|M.avium_104 MSLKTRPKKGLATRINGAPPPRVPLADIHLESLDFWGYDDDFRDGAFATL Mflv_3307|M.gilvum_PYR-GCK -MDGMSLDAHPVRR-NGIAPPEVPLADIDLGSWEFWGLDDDFRDGAFATL Mvan_3029|M.vanbaalenii_PYR-1 MSLGMGIEKSAVTRTNGVAPPEVPLADIDLGSWDFWGLDDDYRDGAFATL MSMEG_3551|M.smegmatis_MC2_155 ----MGIAP----RVNGAAPPDVPLSEINLGSWDFWALDDDIRDGAFATL TH_4175|M.thermoresistible__bu ----MGIAA----RVNGAAPPPVPLADINLGDWTFWALDDDIRDGAFATL MAB_1211c|M.abscessus_ATCC_199 -----------MTAMKTAAELGLPEG-FDFTDPELYG--NRMPHEEFATL MLBr_02088|M.leprae_Br4923 ----MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGT : : . Mb2289|M.bovis_AF2122/97 RREAPISFWPTIELPGFV-AGNGHWALTKYDDVFYASRHPDIFSSYPNIT Rv2266|M.tuberculosis_H37Rv RREAPISFWPTIELPGFV-AGNGHWALTKYDDVFYASRHPDIFSSYPNIT MMAR_3361|M.marinum_M RREAPISFWPPIELAGLT-AGKGHWALTKHDDIHFASRHPEIFHSSPNIV MUL_1282|M.ulcerans_Agy99 RREAPISFWPPIELAGLT-AGKGHWALTKHDDIHFASRHPEIFHSSPNIV MAV_2174|M.avium_104 RREAPISFWPAIEMDGFV-AGNGYWALTKHEDVHFASRHPEIFSSVPNIT Mflv_3307|M.gilvum_PYR-GCK RREAPVSFHRAYITDEDA-EVAGHWALTRHDDVFFASRHPEIFSSALGIT Mvan_3029|M.vanbaalenii_PYR-1 RREAPISFHEAYVIDPDN-EVAGHWALTRHDDVFYASRHPEIFSSALGIT MSMEG_3551|M.smegmatis_MC2_155 RREAPISFHPAFDTEEGFPQGAGHWALTRHDDVFYASRHPELFSSASGIV TH_4175|M.thermoresistible__bu RREAPISFHPEYVDGGGT----GHWALTRYDDVFHASRHPEVFSSASGIT MAB_1211c|M.abscessus_ATCC_199 RREAPVWWNPQPRTVGGF-ADEGYWVISKHRDVREVSLHTDTFSSGRKGA MLBr_02088|M.leprae_Br4923 RADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKAT * :. : .:: . * . *. . . Mb2289|M.bovis_AF2122/97 IN----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAA Rv2266|M.tuberculosis_H37Rv IN----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAA MMAR_3361|M.marinum_M IH----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAS MUL_1282|M.ulcerans_Agy99 IH----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAS MAV_2174|M.avium_104 IN----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAS Mflv_3307|M.gilvum_PYR-GCK VG----DQTPE-LAEYFGSMIAMDDPRHTRLRNIVRSAFTPRVLALIEDS Mvan_3029|M.vanbaalenii_PYR-1 VG----DQTPE-LAEYFGSMIAMDDPRHTRLRNIVRSAFTPRVLALIEDS MSMEG_3551|M.smegmatis_MC2_155 IG----DQTPE-LAEYFGSMIAMDDPRHTRLRNIVRSAFTPRVLAVIEDS TH_4175|M.thermoresistible__bu LG----EQNPD-LTEYFGSMIAMDDPRHGRLRGIVRSAFTPRVVARTEES MAB_1211c|M.abscessus_ATCC_199 IPRLEDHISPEEFQATLSVLINKDAPEHTQLRGLVSRMFTPRSIAALRIT MLBr_02088|M.leprae_Br4923 LAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGD : .: . :: * * * :** :* *:*: : . Mb2289|M.bovis_AF2122/97 VRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRI Rv2266|M.tuberculosis_H37Rv VRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRI MMAR_3361|M.marinum_M VRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGIPEEDHEQI MUL_1282|M.ulcerans_Agy99 VRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGIPEEDHEQI MAV_2174|M.avium_104 VRERARRLVSSLVANHPNGEAELVSELAGPLPLQVICDMMGIPEEDHQRV Mflv_3307|M.gilvum_PYR-GCK VRQRARRLVEDMVAAHPDGRGELVSELAGPLPLQIICDMMGIPPRDHQKI Mvan_3029|M.vanbaalenii_PYR-1 VRQRARSLVQQMVAAHPDGNGELVAELAGPLPLQIICDMMGIPEEDHQKI MSMEG_3551|M.smegmatis_MC2_155 VRDRARRLVAGMVDRNPDGHAELVTELAGPLPLQIICDMMGIPESDHQQI TH_4175|M.thermoresistible__bu VRRRARRLVAAMVAGHPAGAAELVSAFAGPLPLQVICDMMGIPETDHQQI MAB_1211c|M.abscessus_ATCC_199 LEERAERIVRAALEG---GHGEFVREVASELPMQAIAELIGVPEEDRVKL MLBr_02088|M.leprae_Br4923 IAALVDSLLD---KGAAAGQFDVIADLAFPLAVAVICRLLGVPYEDAPEF : . :: :.: .* *.: *. ::*:* * .. Mb2289|M.bovis_AF2122/97 FHWTNVILGFGDPDLATDFDEFMQVSADIGA------YATALAEDRRVNH Rv2266|M.tuberculosis_H37Rv FHWTNVILGFGDPDLATDFDEFMQVSADIGA------YATALAEDRRVNH MMAR_3361|M.marinum_M FHWTNVILGFGDPDLTTDFDEFLQVSMAIGG------YATALADDRRVNH MUL_1282|M.ulcerans_Agy99 FHWTNVILGFGDPDLTTDFDDFLQVSMAIGG------YATALADDRRVNH MAV_2174|M.avium_104 FHWTNVILGFGDPDLATDFEEFLQVSMDIGA------YATALAEDRRVNH Mflv_3307|M.gilvum_PYR-GCK FHWTNVILGFGDPDIATDFDEFVSVAMGIGA------YASELADDRRAHP Mvan_3029|M.vanbaalenii_PYR-1 FHWTNVILGFGDPDIATDFDEFVSVAMGIGA------YATQLADDRRDHP MSMEG_3551|M.smegmatis_MC2_155 FHWTNVILGFGDPDLTTDFDEFVTVAMDIGA------YATALADQRRSAP TH_4175|M.thermoresistible__bu FHWTNVILGFGDPDLTTDYDEFVQVAVDIGG------YATDLAEQRRKNP MAB_1211c|M.abscessus_ATCC_199 FEWSNQMTGYDEADVEIDP---RVGAAQILG------YSYQLAEQRRDCP MLBr_02088|M.leprae_Br4923 GRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTP . : : :. : : . * *.. ** Mb2289|M.bovis_AF2122/97 HDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALS Rv2266|M.tuberculosis_H37Rv HDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALS MMAR_3361|M.marinum_M HGDLTTSLVEAEVDGERLSSSEIAMFFILLVVAGNETTRNAISHGMLALS MUL_1282|M.ulcerans_Agy99 HGDLTTSLVEAEVDGERLSSSEIAMFFILLVVAGNETTRNTISHGMLALS MAV_2174|M.avium_104 HDDLTTSLVEAEVDGERLTSSEIASFFILLVVAGNETTRNAISHGVLALS Mflv_3307|M.gilvum_PYR-GCK GDDLTTALIEAELDGERLTSAEVASFFILLVVAGNETTRNAISHGVLALS Mvan_3029|M.vanbaalenii_PYR-1 GDDLTTSLVAAELDGERLTSAEVASFFILLVVAGNETTRNAISHGVLALS MSMEG_3551|M.smegmatis_MC2_155 ADDLTTSLVQAEVDGERLTSAEVASFFILLVVAGNETTRNAISHGVLALT TH_4175|M.thermoresistible__bu GPDLTTSLVQAEVDGEQLTSADIASFFILLVVAGNETTRNAISHGMLALT MAB_1211c|M.abscessus_ATCC_199 GNDVVSRLLTGTVDGEQLTPEQFGFFVVMLSVAGNETTRNATTMGMMAFL MLBr_02088|M.leprae_Br4923 GEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAML *: : *: .*::*: :. :* ***:*** * : .::*: Mb2289|M.bovis_AF2122/97 RYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMRRTLTQDIELRGTKMA Rv2266|M.tuberculosis_H37Rv RYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMRRTLTQDIELRGTKMA MMAR_3361|M.marinum_M RYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMRRTLSQDVDLRGTKMA MUL_1282|M.ulcerans_Agy99 RYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMRRTLNQDVDLRGTKMA MAV_2174|M.avium_104 RYPDERDKWFSDFDRLTPTAVEEVVRWASPVVYMRRTLTRDVKLRGTKMK Mflv_3307|M.gilvum_PYR-GCK RYPEERDRWWSDYAGLAPTAVEEIVRWASPVAYMRRTATRDVEVGGQTIA Mvan_3029|M.vanbaalenii_PYR-1 RYPEQRQRWWSDYQGMAPTAVEEIVRWASPVAYMRRTATRDVEMSGVRIA MSMEG_3551|M.smegmatis_MC2_155 RYPEQRRLWWSRFDELAPTAVEEIVRWASPVSYMRRTVTRDTELAGTALP TH_4175|M.thermoresistible__bu RHPDQRQDWWDHFDEVTPTAVEEIVRWASPVTYMRRTVTRDTELRGVRMA MAB_1211c|M.abscessus_ATCC_199 EHPGQWELFKS---ARPSTTVDEIVRYTSPLISQQRTALQDTVISDVRIR MLBr_02088|M.leprae_Br4923 RNPSQWKALSSN-PQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTLT . * : . .. .*:* :*: ..: *. :* : : Mb2289|M.bovis_AF2122/97 AGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANL Rv2266|M.tuberculosis_H37Rv AGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANL MMAR_3361|M.marinum_M AGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGGGAHFCLGANL MUL_1282|M.ulcerans_Agy99 AGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGGGAHFCLGANL MAV_2174|M.avium_104 AGDKVALWYNSANRDESTFDNPWLFDVARTPNPHLGFGGGGAHFCLGANL Mflv_3307|M.gilvum_PYR-GCK AGDKVTLWYGSANRDETKFDNPWLFDVGRHPNPHVGFGGGGAHFCLGANL Mvan_3029|M.vanbaalenii_PYR-1 AGDKVSLWYGSANRDESKFENPWLFDVGRHPNPHVGFGGGGAHFCLGANL MSMEG_3551|M.smegmatis_MC2_155 AGSKVTLWYGSANRDETKFDNPWMFDVQRHPNPHVGFGGGGAHFCLGANL TH_4175|M.thermoresistible__bu AGDKVTLWYGSANRDESRFSDPWLFDVRRHPNPHVGFGGGGVHFCLGANL MAB_1211c|M.abscessus_ATCC_199 AGERVVMLYPSANFDEEVFENPHTFDITRDPNPHLGFGGTGAHYCLGANL MLBr_02088|M.leprae_Br4923 EGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVG-SHFCLGAAL *. : : :** * : * ** * .. ::.*. *:**** * Mb2289|M.bovis_AF2122/97 ARREIRVAFDELRRQMPDVVATEEPARLLSQFIHGIKT------------ Rv2266|M.tuberculosis_H37Rv ARREIRVAFDELRRQMPDVVATEEPARLLSQFIHGIKT------------ MMAR_3361|M.marinum_M ARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKR------------ MUL_1282|M.ulcerans_Agy99 ARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKR------------ MAV_2174|M.avium_104 ARREIRVVFDELRHEIPDIVATEEPARLLSQFIHGIKR------------ Mflv_3307|M.gilvum_PYR-GCK ARREITVAFEELHRLVPDIHATEEPGRLHSAFIHGIKT------------ Mvan_3029|M.vanbaalenii_PYR-1 ARREITVAFEELHRLVPGIRAVEEPDRLHSAFIHGIKR------------ MSMEG_3551|M.smegmatis_MC2_155 ARREITVLFSELHRHLPDIVATEEPDRLQSAFIHGIKR------------ TH_4175|M.thermoresistible__bu ARREIAVAFDELRRQVPDIEVTEEPDRLHSAFIHGIXXXAEPESLPEPPP MAB_1211c|M.abscessus_ATCC_199 AKAELEIIFNKIADRMPDISRIGDAPRFHSGWINGIKK------------ MLBr_02088|M.leprae_Br4923 ARLEATVTLSAISARFPQVQLAGELVYKPNVAMRGMSA------------ *: * : :. : .* : : . :.*: Mb2289|M.bovis_AF2122/97 --------------------------------LPVTWS------------ Rv2266|M.tuberculosis_H37Rv --------------------------------LPVTWS------------ MMAR_3361|M.marinum_M --------------------------------LPVAWSR----------- MUL_1282|M.ulcerans_Agy99 --------------------------------LPVAWSR----------- MAV_2174|M.avium_104 --------------------------------LPVAWTPPR--------- Mflv_3307|M.gilvum_PYR-GCK --------------------------------LPVAWTPPTR-------- Mvan_3029|M.vanbaalenii_PYR-1 --------------------------------LPVSWSA----------- MSMEG_3551|M.smegmatis_MC2_155 --------------------------------LPVAWR------------ TH_4175|M.thermoresistible__bu VASPSEALVNPRFLVAPPEPPAVGPSAFVPPMLGVSSSAPTSTERSSSSE MAB_1211c|M.abscessus_ATCC_199 --------------------------------FDTAYCPVTH-------- MLBr_02088|M.leprae_Br4923 --------------------------------LPVQV------------- : . Mb2289|M.bovis_AF2122/97 -------------------------------------------------- Rv2266|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3361|M.marinum_M -------------------------------------------------- MUL_1282|M.ulcerans_Agy99 -------------------------------------------------- MAV_2174|M.avium_104 -------------------------------------------------- Mflv_3307|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3029|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3551|M.smegmatis_MC2_155 -------------------------------------------------- TH_4175|M.thermoresistible__bu PASVSTTSTPPFSEVASVRAALLAFLAGLSTKPATSTVSASDPWPVLSPT MAB_1211c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_02088|M.leprae_Br4923 -------------------------------------------------- Mb2289|M.bovis_AF2122/97 -------------------------------------------------- Rv2266|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_3361|M.marinum_M -------------------------------------------------- MUL_1282|M.ulcerans_Agy99 -------------------------------------------------- MAV_2174|M.avium_104 -------------------------------------------------- Mflv_3307|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3029|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3551|M.smegmatis_MC2_155 -------------------------------------------------- TH_4175|M.thermoresistible__bu ASPPLASPSPSSKPTATNSPLPVLGSPTPPAADGADFSAALNNPPKGFVG MAB_1211c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_02088|M.leprae_Br4923 -------------------------------------------------- Mb2289|M.bovis_AF2122/97 ----------------------------------- Rv2266|M.tuberculosis_H37Rv ----------------------------------- MMAR_3361|M.marinum_M ----------------------------------- MUL_1282|M.ulcerans_Agy99 ----------------------------------- MAV_2174|M.avium_104 ----------------------------------- Mflv_3307|M.gilvum_PYR-GCK ----------------------------------- Mvan_3029|M.vanbaalenii_PYR-1 ----------------------------------- MSMEG_3551|M.smegmatis_MC2_155 ----------------------------------- TH_4175|M.thermoresistible__bu TPPEAPSASAIARGRVTVSTSTSPGIPSAPTRSPG MAB_1211c|M.abscessus_ATCC_199 ----------------------------------- MLBr_02088|M.leprae_Br4923 -----------------------------------