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M. thermoresistible (build 8) TH_4175 (-)

annotation: linalool 8-monooxygenase
coordinates: 3811462 - 3813300
length: 613

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4175--100% (613)linalool 8-monooxygenase
M. thermoresistible (build 8)TH_1956-4e-8341.54% (402) PROBABLE CYTOCHROME P450 125 CYP125
M. thermoresistible (build 8)TH_3205-2e-8141.48% (393) PUTATIVE NikQ protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2289cyp1241e-17972.46% (414) cytochrome P450 124 CYP124
M. gilvum PYR-GCKMflv_3307-0.074.94% (411) cytochrome P450
M. tuberculosis H37RvRv2266cyp1241e-17972.46% (414) cytochrome P450 124 CYP124
M. leprae Br4923MLBr_02088-2e-3830.72% (345) putative cytochrome p450
M. abscessus ATCC 19977MAB_1211c-2e-7741.41% (384) cytochrome P450
M. marinum MMMAR_3361cyp124A11e-17771.81% (415) cytochrome P450 124A1, Cyp124A1
M. avium 104MAV_2174-1e-17872.53% (415) P450 heme-thiolate protein
M. smegmatis MC2 155MSMEG_3551-0.078.90% (417) linalool 8-monooxygenase
M. ulcerans Agy99MUL_1282cyp124A11e-17671.33% (415) cytochrome P450 124A1, Cyp124A1
M. vanbaalenii PYR-1Mvan_3029-0.076.64% (411) cytochrome P450

CLUSTAL 2.0.9 multiple sequence alignment


Mb2289|M.bovis_AF2122/97            ----MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFATL
Rv2266|M.tuberculosis_H37Rv         ----MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFATL
MMAR_3361|M.marinum_M               MDLSTNLNTGLLPRVNGTPPPEVPLADIELGSLEFWGRDDDFRDGAFATL
MUL_1282|M.ulcerans_Agy99           MDLSTNLNTGLLPRVNGTPPPEVPLADIELGSLEFWGRDDDFRDGAFATL
MAV_2174|M.avium_104                MSLKTRPKKGLATRINGAPPPRVPLADIHLESLDFWGYDDDFRDGAFATL
Mflv_3307|M.gilvum_PYR-GCK          -MDGMSLDAHPVRR-NGIAPPEVPLADIDLGSWEFWGLDDDFRDGAFATL
Mvan_3029|M.vanbaalenii_PYR-1       MSLGMGIEKSAVTRTNGVAPPEVPLADIDLGSWDFWGLDDDYRDGAFATL
MSMEG_3551|M.smegmatis_MC2_155      ----MGIAP----RVNGAAPPDVPLSEINLGSWDFWALDDDIRDGAFATL
TH_4175|M.thermoresistible__bu      ----MGIAA----RVNGAAPPPVPLADINLGDWTFWALDDDIRDGAFATL
MAB_1211c|M.abscessus_ATCC_199      -----------MTAMKTAAELGLPEG-FDFTDPELYG--NRMPHEEFATL
MLBr_02088|M.leprae_Br4923          ----MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGT
                                                               :      :            .  

Mb2289|M.bovis_AF2122/97            RREAPISFWPTIELPGFV-AGNGHWALTKYDDVFYASRHPDIFSSYPNIT
Rv2266|M.tuberculosis_H37Rv         RREAPISFWPTIELPGFV-AGNGHWALTKYDDVFYASRHPDIFSSYPNIT
MMAR_3361|M.marinum_M               RREAPISFWPPIELAGLT-AGKGHWALTKHDDIHFASRHPEIFHSSPNIV
MUL_1282|M.ulcerans_Agy99           RREAPISFWPPIELAGLT-AGKGHWALTKHDDIHFASRHPEIFHSSPNIV
MAV_2174|M.avium_104                RREAPISFWPAIEMDGFV-AGNGYWALTKHEDVHFASRHPEIFSSVPNIT
Mflv_3307|M.gilvum_PYR-GCK          RREAPVSFHRAYITDEDA-EVAGHWALTRHDDVFFASRHPEIFSSALGIT
Mvan_3029|M.vanbaalenii_PYR-1       RREAPISFHEAYVIDPDN-EVAGHWALTRHDDVFYASRHPEIFSSALGIT
MSMEG_3551|M.smegmatis_MC2_155      RREAPISFHPAFDTEEGFPQGAGHWALTRHDDVFYASRHPELFSSASGIV
TH_4175|M.thermoresistible__bu      RREAPISFHPEYVDGGGT----GHWALTRYDDVFHASRHPEVFSSASGIT
MAB_1211c|M.abscessus_ATCC_199      RREAPVWWNPQPRTVGGF-ADEGYWVISKHRDVREVSLHTDTFSSGRKGA
MLBr_02088|M.leprae_Br4923          RADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKAT
                                    * :.   :                 .:: . *   .  *.    .    .

Mb2289|M.bovis_AF2122/97            IN----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAA
Rv2266|M.tuberculosis_H37Rv         IN----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAA
MMAR_3361|M.marinum_M               IH----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAS
MUL_1282|M.ulcerans_Agy99           IH----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAS
MAV_2174|M.avium_104                IN----DQTPE-LAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAS
Mflv_3307|M.gilvum_PYR-GCK          VG----DQTPE-LAEYFGSMIAMDDPRHTRLRNIVRSAFTPRVLALIEDS
Mvan_3029|M.vanbaalenii_PYR-1       VG----DQTPE-LAEYFGSMIAMDDPRHTRLRNIVRSAFTPRVLALIEDS
MSMEG_3551|M.smegmatis_MC2_155      IG----DQTPE-LAEYFGSMIAMDDPRHTRLRNIVRSAFTPRVLAVIEDS
TH_4175|M.thermoresistible__bu      LG----EQNPD-LTEYFGSMIAMDDPRHGRLRGIVRSAFTPRVVARTEES
MAB_1211c|M.abscessus_ATCC_199      IPRLEDHISPEEFQATLSVLINKDAPEHTQLRGLVSRMFTPRSIAALRIT
MLBr_02088|M.leprae_Br4923          LAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGD
                                    :        .:      . ::  * * * :** :*   *:*: :   .  

Mb2289|M.bovis_AF2122/97            VRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRI
Rv2266|M.tuberculosis_H37Rv         VRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRI
MMAR_3361|M.marinum_M               VRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGIPEEDHEQI
MUL_1282|M.ulcerans_Agy99           VRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGIPEEDHEQI
MAV_2174|M.avium_104                VRERARRLVSSLVANHPNGEAELVSELAGPLPLQVICDMMGIPEEDHQRV
Mflv_3307|M.gilvum_PYR-GCK          VRQRARRLVEDMVAAHPDGRGELVSELAGPLPLQIICDMMGIPPRDHQKI
Mvan_3029|M.vanbaalenii_PYR-1       VRQRARSLVQQMVAAHPDGNGELVAELAGPLPLQIICDMMGIPEEDHQKI
MSMEG_3551|M.smegmatis_MC2_155      VRDRARRLVAGMVDRNPDGHAELVTELAGPLPLQIICDMMGIPESDHQQI
TH_4175|M.thermoresistible__bu      VRRRARRLVAAMVAGHPAGAAELVSAFAGPLPLQVICDMMGIPETDHQQI
MAB_1211c|M.abscessus_ATCC_199      LEERAERIVRAALEG---GHGEFVREVASELPMQAIAELIGVPEEDRVKL
MLBr_02088|M.leprae_Br4923          IAALVDSLLD---KGAAAGQFDVIADLAFPLAVAVICRLLGVPYEDAPEF
                                    :   .  ::            :.:  .*  *.:  *. ::*:*  *  ..

Mb2289|M.bovis_AF2122/97            FHWTNVILGFGDPDLATDFDEFMQVSADIGA------YATALAEDRRVNH
Rv2266|M.tuberculosis_H37Rv         FHWTNVILGFGDPDLATDFDEFMQVSADIGA------YATALAEDRRVNH
MMAR_3361|M.marinum_M               FHWTNVILGFGDPDLTTDFDEFLQVSMAIGG------YATALADDRRVNH
MUL_1282|M.ulcerans_Agy99           FHWTNVILGFGDPDLTTDFDDFLQVSMAIGG------YATALADDRRVNH
MAV_2174|M.avium_104                FHWTNVILGFGDPDLATDFEEFLQVSMDIGA------YATALAEDRRVNH
Mflv_3307|M.gilvum_PYR-GCK          FHWTNVILGFGDPDIATDFDEFVSVAMGIGA------YASELADDRRAHP
Mvan_3029|M.vanbaalenii_PYR-1       FHWTNVILGFGDPDIATDFDEFVSVAMGIGA------YATQLADDRRDHP
MSMEG_3551|M.smegmatis_MC2_155      FHWTNVILGFGDPDLTTDFDEFVTVAMDIGA------YATALADQRRSAP
TH_4175|M.thermoresistible__bu      FHWTNVILGFGDPDLTTDYDEFVQVAVDIGG------YATDLAEQRRKNP
MAB_1211c|M.abscessus_ATCC_199      FEWSNQMTGYDEADVEIDP---RVGAAQILG------YSYQLAEQRRDCP
MLBr_02088|M.leprae_Br4923          GRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTP
                                     . :  :    :. :             : .      *   *.. **   

Mb2289|M.bovis_AF2122/97            HDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALS
Rv2266|M.tuberculosis_H37Rv         HDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALS
MMAR_3361|M.marinum_M               HGDLTTSLVEAEVDGERLSSSEIAMFFILLVVAGNETTRNAISHGMLALS
MUL_1282|M.ulcerans_Agy99           HGDLTTSLVEAEVDGERLSSSEIAMFFILLVVAGNETTRNTISHGMLALS
MAV_2174|M.avium_104                HDDLTTSLVEAEVDGERLTSSEIASFFILLVVAGNETTRNAISHGVLALS
Mflv_3307|M.gilvum_PYR-GCK          GDDLTTALIEAELDGERLTSAEVASFFILLVVAGNETTRNAISHGVLALS
Mvan_3029|M.vanbaalenii_PYR-1       GDDLTTSLVAAELDGERLTSAEVASFFILLVVAGNETTRNAISHGVLALS
MSMEG_3551|M.smegmatis_MC2_155      ADDLTTSLVQAEVDGERLTSAEVASFFILLVVAGNETTRNAISHGVLALT
TH_4175|M.thermoresistible__bu      GPDLTTSLVQAEVDGEQLTSADIASFFILLVVAGNETTRNAISHGMLALT
MAB_1211c|M.abscessus_ATCC_199      GNDVVSRLLTGTVDGEQLTPEQFGFFVVMLSVAGNETTRNATTMGMMAFL
MLBr_02088|M.leprae_Br4923          GEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANAVLAML
                                      *: : *:    .*::*:  :.     :* ***:*** *  : .::*: 

Mb2289|M.bovis_AF2122/97            RYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMRRTLTQDIELRGTKMA
Rv2266|M.tuberculosis_H37Rv         RYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMRRTLTQDIELRGTKMA
MMAR_3361|M.marinum_M               RYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMRRTLSQDVDLRGTKMA
MUL_1282|M.ulcerans_Agy99           RYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMRRTLNQDVDLRGTKMA
MAV_2174|M.avium_104                RYPDERDKWFSDFDRLTPTAVEEVVRWASPVVYMRRTLTRDVKLRGTKMK
Mflv_3307|M.gilvum_PYR-GCK          RYPEERDRWWSDYAGLAPTAVEEIVRWASPVAYMRRTATRDVEVGGQTIA
Mvan_3029|M.vanbaalenii_PYR-1       RYPEQRQRWWSDYQGMAPTAVEEIVRWASPVAYMRRTATRDVEMSGVRIA
MSMEG_3551|M.smegmatis_MC2_155      RYPEQRRLWWSRFDELAPTAVEEIVRWASPVSYMRRTVTRDTELAGTALP
TH_4175|M.thermoresistible__bu      RHPDQRQDWWDHFDEVTPTAVEEIVRWASPVTYMRRTVTRDTELRGVRMA
MAB_1211c|M.abscessus_ATCC_199      EHPGQWELFKS---ARPSTTVDEIVRYTSPLISQQRTALQDTVISDVRIR
MLBr_02088|M.leprae_Br4923          RNPSQWKALSSN-PQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTLT
                                    . * :     .     .. .*:* :*: ..:    *.  :*  :    : 

Mb2289|M.bovis_AF2122/97            AGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANL
Rv2266|M.tuberculosis_H37Rv         AGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANL
MMAR_3361|M.marinum_M               AGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGGGAHFCLGANL
MUL_1282|M.ulcerans_Agy99           AGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGGGAHFCLGANL
MAV_2174|M.avium_104                AGDKVALWYNSANRDESTFDNPWLFDVARTPNPHLGFGGGGAHFCLGANL
Mflv_3307|M.gilvum_PYR-GCK          AGDKVTLWYGSANRDETKFDNPWLFDVGRHPNPHVGFGGGGAHFCLGANL
Mvan_3029|M.vanbaalenii_PYR-1       AGDKVSLWYGSANRDESKFENPWLFDVGRHPNPHVGFGGGGAHFCLGANL
MSMEG_3551|M.smegmatis_MC2_155      AGSKVTLWYGSANRDETKFDNPWMFDVQRHPNPHVGFGGGGAHFCLGANL
TH_4175|M.thermoresistible__bu      AGDKVTLWYGSANRDESRFSDPWLFDVRRHPNPHVGFGGGGVHFCLGANL
MAB_1211c|M.abscessus_ATCC_199      AGERVVMLYPSANFDEEVFENPHTFDITRDPNPHLGFGGTGAHYCLGANL
MLBr_02088|M.leprae_Br4923          EGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVG-SHFCLGAAL
                                     *. : :   :** *   :  *  **  * .. ::.*.    *:**** *

Mb2289|M.bovis_AF2122/97            ARREIRVAFDELRRQMPDVVATEEPARLLSQFIHGIKT------------
Rv2266|M.tuberculosis_H37Rv         ARREIRVAFDELRRQMPDVVATEEPARLLSQFIHGIKT------------
MMAR_3361|M.marinum_M               ARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKR------------
MUL_1282|M.ulcerans_Agy99           ARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKR------------
MAV_2174|M.avium_104                ARREIRVVFDELRHEIPDIVATEEPARLLSQFIHGIKR------------
Mflv_3307|M.gilvum_PYR-GCK          ARREITVAFEELHRLVPDIHATEEPGRLHSAFIHGIKT------------
Mvan_3029|M.vanbaalenii_PYR-1       ARREITVAFEELHRLVPGIRAVEEPDRLHSAFIHGIKR------------
MSMEG_3551|M.smegmatis_MC2_155      ARREITVLFSELHRHLPDIVATEEPDRLQSAFIHGIKR------------
TH_4175|M.thermoresistible__bu      ARREIAVAFDELRRQVPDIEVTEEPDRLHSAFIHGIXXXAEPESLPEPPP
MAB_1211c|M.abscessus_ATCC_199      AKAELEIIFNKIADRMPDISRIGDAPRFHSGWINGIKK------------
MLBr_02088|M.leprae_Br4923          ARLEATVTLSAISARFPQVQLAGELVYKPNVAMRGMSA------------
                                    *: *  : :. :   .* :    :     .  :.*:              

Mb2289|M.bovis_AF2122/97            --------------------------------LPVTWS------------
Rv2266|M.tuberculosis_H37Rv         --------------------------------LPVTWS------------
MMAR_3361|M.marinum_M               --------------------------------LPVAWSR-----------
MUL_1282|M.ulcerans_Agy99           --------------------------------LPVAWSR-----------
MAV_2174|M.avium_104                --------------------------------LPVAWTPPR---------
Mflv_3307|M.gilvum_PYR-GCK          --------------------------------LPVAWTPPTR--------
Mvan_3029|M.vanbaalenii_PYR-1       --------------------------------LPVSWSA-----------
MSMEG_3551|M.smegmatis_MC2_155      --------------------------------LPVAWR------------
TH_4175|M.thermoresistible__bu      VASPSEALVNPRFLVAPPEPPAVGPSAFVPPMLGVSSSAPTSTERSSSSE
MAB_1211c|M.abscessus_ATCC_199      --------------------------------FDTAYCPVTH--------
MLBr_02088|M.leprae_Br4923          --------------------------------LPVQV-------------
                                                                    : .               

Mb2289|M.bovis_AF2122/97            --------------------------------------------------
Rv2266|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_3361|M.marinum_M               --------------------------------------------------
MUL_1282|M.ulcerans_Agy99           --------------------------------------------------
MAV_2174|M.avium_104                --------------------------------------------------
Mflv_3307|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3029|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3551|M.smegmatis_MC2_155      --------------------------------------------------
TH_4175|M.thermoresistible__bu      PASVSTTSTPPFSEVASVRAALLAFLAGLSTKPATSTVSASDPWPVLSPT
MAB_1211c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02088|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2289|M.bovis_AF2122/97            --------------------------------------------------
Rv2266|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_3361|M.marinum_M               --------------------------------------------------
MUL_1282|M.ulcerans_Agy99           --------------------------------------------------
MAV_2174|M.avium_104                --------------------------------------------------
Mflv_3307|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3029|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3551|M.smegmatis_MC2_155      --------------------------------------------------
TH_4175|M.thermoresistible__bu      ASPPLASPSPSSKPTATNSPLPVLGSPTPPAADGADFSAALNNPPKGFVG
MAB_1211c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02088|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2289|M.bovis_AF2122/97            -----------------------------------
Rv2266|M.tuberculosis_H37Rv         -----------------------------------
MMAR_3361|M.marinum_M               -----------------------------------
MUL_1282|M.ulcerans_Agy99           -----------------------------------
MAV_2174|M.avium_104                -----------------------------------
Mflv_3307|M.gilvum_PYR-GCK          -----------------------------------
Mvan_3029|M.vanbaalenii_PYR-1       -----------------------------------
MSMEG_3551|M.smegmatis_MC2_155      -----------------------------------
TH_4175|M.thermoresistible__bu      TPPEAPSASAIARGRVTVSTSTSPGIPSAPTRSPG
MAB_1211c|M.abscessus_ATCC_199      -----------------------------------
MLBr_02088|M.leprae_Br4923          -----------------------------------