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M. thermoresistible (build 8) TH_4098 (-)

annotation: NADH dehydrogenase (quinone)
coordinates: 1875783 - 1878686
length: 968

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4098--100% (968)NADH dehydrogenase (quinone)
M. thermoresistible (build 8)TH_1090nuoL6e-4831.75% (485) PROBABLE NADH DEHYDROGENASE I (CHAIN L) NUOL
M. thermoresistible (build 8)TH_4005-3e-3329.76% (457) PUTATIVE NADH-ubiquinone oxidoreductase/multisubunit na+/h+

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3180nuoL1e-4528.47% (562) NADH dehydrogenase subunit L
M. gilvum PYR-GCKMflv_0162-0.075.94% (956) putative monovalent cation/H+ antiporter subunit A
M. tuberculosis H37RvRv3156nuoL1e-4528.47% (562) NADH dehydrogenase subunit L
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0636c-0.067.08% (966) putative monovalent cation/H+ antiporter subunit A
M. marinum MMMAR_1472nuoL4e-4630.06% (479) NADH dehydrogenase I (chain L) NuoL (NADH- ubiquinone
M. avium 104MAV_4044-5e-4730.34% (468) NADH dehydrogenase subunit L
M. smegmatis MC2 155MSMEG_0848-0.074.95% (966) putative monovalent cation/H+ antiporter subunit A
M. ulcerans Agy99MUL_2470nuoL4e-4631.36% (456) NADH dehydrogenase subunit L
M. vanbaalenii PYR-1Mvan_0744-0.076.57% (956) putative monovalent cation/H+ antiporter subunit A

CLUSTAL 2.0.9 multiple sequence alignment


Mb3180|M.bovis_AF2122/97            MTTSLG-------THYTWLLVALPLAGAAILLFGGRRTDAWGHLLGCAAA
Rv3156|M.tuberculosis_H37Rv         MTTSLG-------THYTWLLVALPLAGAAILLFGGRRTDAWGHLLGCAAA
MMAR_1472|M.marinum_M               MTNFLG-------TQHTWLLVALPLAGAAILLFGGRRTDAWGHWLGCAAA
MUL_2470|M.ulcerans_Agy99           MTNFLG-------TQHTWLLVALPLAGAAILLFGGRRTDAWGHWLGCAAA
MAV_4044|M.avium_104                MTRTYSKAEHANMTHYTPLLVALPLAGAAILLFGGRRTDRWGHWLGCATA
Mflv_0162|M.gilvum_PYR-GCK          -------------------MLAILAAHAAAALLAPLLVYRWGRLAFYPLA
Mvan_0744|M.vanbaalenii_PYR-1       -------------------MLAILAAHAVATLLAPLLVYRWGRMAFYPLA
MSMEG_0848|M.smegmatis_MC2_155      -------------------MLAVLLAHAVATALAPLMVARWGRMAFFPLS
TH_4098|M.thermoresistible__bu      -------------------MLAILIAHAIATALAPLLVYRWDRKAFYPLA
MAB_0636c|M.abscessus_ATCC_199      -------------------MLAILLAHALAAAVAPLLVARMGRLAFYPLA
                                                       ::*:  * *    ..   .   .:    . :

Mb3180|M.bovis_AF2122/97            LAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGGLQVDFGLQIDQLSM
Rv3156|M.tuberculosis_H37Rv         LAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGGLQVDFGLQIDQLSM
MMAR_1472|M.marinum_M               LASFGVGATMLADLVGRSADDRLIHQTVFTWMPVSQLQVDFGLQIDQLSI
MUL_2470|M.ulcerans_Agy99           LASFGVGATMLADLVGRSADDRLIHQTVFTWMPVSQLQVDFGLQIDQLSI
MAV_4044|M.avium_104                VAAFVVGVGLLDELLGRPADQRAIHERVFSWIPVGQLQVDLGLQIDQLSV
Mflv_0162|M.gilvum_PYR-GCK          LVPLGSLVWVVLNWPAKG----QSRNVDVPWVP--GLSMDITLRFDALAA
Mvan_0744|M.vanbaalenii_PYR-1       LVPLGSLFWVVLNWPAKG----QSHTVDVSWVP--ELSMDITLRFDALAA
MSMEG_0848|M.smegmatis_MC2_155      LVPLGSLVWVALNWPSPD----NIPTVHVSWVP--ELWMDFTLRFDALAA
TH_4098|M.thermoresistible__bu      LVPLGSLVWVALNWPRDG----HVPTTDIEWVP--ELAMDVNLRFDSLAA
MAB_0636c|M.abscessus_ATCC_199      LVPFGSLIWVLARWPGNS----PGVRVDIPWVP--ELAMDIALRFDALAA
                                    :..:     :                  . *:*   * :*. *::* *: 

Mb3180|M.bovis_AF2122/97            CFVLLISGVGSLIHIYSVGYMAEDPDRRR-----FFGYLNLFLASMLLLV
Rv3156|M.tuberculosis_H37Rv         CFVLLISGVGSLIHIYSVGYMAEDPDRRR-----FFGYLNLFLASMLLLV
MMAR_1472|M.marinum_M               CFVLLITGVGSLIHIYSVAYMAEDPDRRR-----FFGYLNLFLASMLLLV
MUL_2470|M.ulcerans_Agy99           CFVLLITGVGSLIHIYSVAYMAEDPDRRR-----FFGYLNLFLASMLLLV
MAV_4044|M.avium_104                CFVLLITGVGSLIHIYSVAYMAEDADRRR-----FFGYLNLFLASMLLLV
Mflv_0162|M.gilvum_PYR-GCK          IMSVLVLAIGALVLFYCADYFRHHDGRIEKRLPSFAAELVAFSGAMFGLV
Mvan_0744|M.vanbaalenii_PYR-1       VMSVLVLAIGALVLFYCADYFHHHDGHKEKRLPSFAAELVAFSGAMFGLV
MSMEG_0848|M.smegmatis_MC2_155      IMSVLVLAIGALVLFYCAHYFHHHDGRMEKRLPSFAAELVAFSGAMFGLV
TH_4098|M.thermoresistible__bu      VMSVLVLAIGALVLFYCGDYFHHHDGRREKRLPSFAAELVAFSGAMFGLV
MAB_0636c|M.abscessus_ATCC_199      IMSVLVLGIGSLVLFYCASYFRHRDGHTEPRLPSFAAELVAFSGAMFGLV
                                     : :*: .:*:*: :*.  *: .  .: .     * . *  * .:*: **

Mb3180|M.bovis_AF2122/97            VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL
Rv3156|M.tuberculosis_H37Rv         VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL
MMAR_1472|M.marinum_M               VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL
MUL_2470|M.ulcerans_Agy99           VADNYVLLYVGWEGVGLASYLLIGFWYHKASAATAAKKAFVMNRVGDAGL
MAV_4044|M.avium_104                IADNYVVLYVGWEGVGLASYLLIGFWYHKPTAATAAKKAFVMNRVGDAGL
Mflv_0162|M.gilvum_PYR-GCK          TSDNMLVLYVFWEITTVLSFLLVGHYAERATTRRAAMQALLVTTFGGLAM
Mvan_0744|M.vanbaalenii_PYR-1       TSDNMLVLYVFWEITTVLSFLLVGHYAERATSRRSAMQALLVTTFGGLAM
MSMEG_0848|M.smegmatis_MC2_155      VSDNMLVLYIFWETTTVLSFLLVGHYAERATSRRAATQALLVTTFGGLAM
TH_4098|M.thermoresistible__bu      VSDNMLVLYVFWEITTVLSFLLVGHYAERATSRRAATQALLVTTFGGLAM
MAB_0636c|M.abscessus_ATCC_199      ISDNLLVLYIFWELTTVLSFLLVGHYAERLASRRAAVQALLVTTAGGLAM
                                     :** ::**: ** . : *:**:*.: .: ::  :* :*:::.  *. .:

Mb3180|M.bovis_AF2122/97            AVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACAKSAQVP
Rv3156|M.tuberculosis_H37Rv         AVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACAKSAQVP
MMAR_1472|M.marinum_M               ALGMFVMFSTFGTLSYAGVFAGAPAASRGALTAMGLLLLLGACAKSAQVP
MUL_2470|M.ulcerans_Agy99           ALGMFVMFSTFGTLSYAGVFAGAPAASRGALTAMGLLLLLGACAKSAQVP
MAV_4044|M.avium_104                ALGMFLMFSTFGTLSYAGVFAGAPAAGRGALTAMGLLLLLGACAKSAQVP
Mflv_0162|M.gilvum_PYR-GCK          LVGIVVIGNIADTFLLSELIANPPTG--VAASVALVLILVGALSKSAIVP
Mvan_0744|M.vanbaalenii_PYR-1       LVGIVVIGNIAGTFLLSELIADPPTG--LAASVAVVLILVGALSKSAIVP
MSMEG_0848|M.smegmatis_MC2_155      LTGIVVLGNMAGTYLLSELIAAPPTG--TAASVGIALILIGALSKSAIVP
TH_4098|M.thermoresistible__bu      LAGIVVLGNLAGTYLLSELIAAPPTG--VAATVAVVLVLVGALSKSAIVP
MAB_0636c|M.abscessus_ATCC_199      LVGVIVLGHVGGSFLLSDLIANPPTG--LAASVGLVLVLIGALSKSAIVP
                                      *:.:     .:   : ::*  *:.   . :.   *:*:** :*** **

Mb3180|M.bovis_AF2122/97            LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPTAQLAVV
Rv3156|M.tuberculosis_H37Rv         LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPTAQLAVV
MMAR_1472|M.marinum_M               LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNPLYNLAPDAQLAVV
MUL_2470|M.ulcerans_Agy99           LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNLLYNLAPDAQLAVV
MAV_4044|M.avium_104                LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNPLYNLSPDAQLAVV
Mflv_0162|M.gilvum_PYR-GCK          LHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPEWRPTVV
Mvan_0744|M.vanbaalenii_PYR-1       MHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPEWRPTVV
MSMEG_0848|M.smegmatis_MC2_155      MHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADTAFWRPMVI
TH_4098|M.thermoresistible__bu      LHFWLPGAMAAPSPVSAYLHAAAMVKAGVYLVARMTPGFADFSVWRPMAI
MAB_0636c|M.abscessus_ATCC_199      LHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLLARMSPGFAEAAPWRPVVL
                                    :: ** .** .*:**** :***:**.**:**:.*    :   .  :  .:

Mb3180|M.bovis_AF2122/97            IVGAVTLLYGAIIGCAKDDIKRALAASTISQIGYMVLAAGLGPAGYAFA-
Rv3156|M.tuberculosis_H37Rv         IVGAVTLLFGAIIGCAKDDIKRALAASTISQIGYMVLAAGLGPAGYAFA-
MMAR_1472|M.marinum_M               VVGTVTLLLGAVIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA-
MUL_2470|M.ulcerans_Agy99           VVGTVTLLLGGVIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA-
MAV_4044|M.avium_104                IVGAVTLLLGAFIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA-
Mflv_0162|M.gilvum_PYR-GCK          GLGLLTMLLAGWRAIREYDLKLILAFGTVSQLGFITIMVGVGGSEMMLAG
Mvan_0744|M.vanbaalenii_PYR-1       TLGLLTMLLAGWRAIREYDLKLILAFGTVSQLGFITVMVGVGGSEMMLAG
MSMEG_0848|M.smegmatis_MC2_155      GLGLLTMLLAGWRAVREYDLKLILAFGTVSQLGLITVMVGAGGPDMMLAG
TH_4098|M.thermoresistible__bu      VLGLATLLLAGWRAIREYDLKLILAFGTVSQLGLITVLVSAGSGDLMLAG
MAB_0636c|M.abscessus_ATCC_199      VLGIATMILAGWRALREYDLKLILAFGTVSQLGFLVVLTGTGDPDILLAG
                                     :*  *:: ..  .  : *:*  ** .*:**:* :.: .. *     :* 

Mb3180|M.bovis_AF2122/97            IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFATFGL
Rv3156|M.tuberculosis_H37Rv         IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFATFGL
MMAR_1472|M.marinum_M               IMHLLTHGFFKAGLFLGSGSVIHAMHEEQDMRRYGGLRAALPVTFVTFGL
MUL_2470|M.ulcerans_Agy99           IMHLLTHGFFKAGLFLGSGSVIHAIHEEQDMRRYGGLRAALPVTFVTFGL
MAV_4044|M.avium_104                IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFVTFGL
Mflv_0162|M.gilvum_PYR-GCK          LAMLCAHAMFKAALFMVVGIIDHATG-TRDIRRLAWLGDRSKPLLIIGCA
Mvan_0744|M.vanbaalenii_PYR-1       LAMLCAHAMFKAALFMTVGIIDHATG-TRDIRRLAWLGDRSRPLLIVGCA
MSMEG_0848|M.smegmatis_MC2_155      LAMLIAHAMFKASLFMVVGVIDHATG-TRDIRRLAGLGRAHRPLLIIALG
TH_4098|M.thermoresistible__bu      LAMLVAHAMFKAALFMVVGIIDHTTG-TRDIRRLAWLGNRNKPLLVIAVA
MAB_0636c|M.abscessus_ATCC_199      LVMLCAHALFKAALFMVVGIIDHTVG-TRDIRKLAWLGNRQPPLLVIAGI
                                    :  * :*.:***.**:  * : *:    :*:*: . *       :     

Mb3180|M.bovis_AF2122/97            AYLAIIGVPPFAGFFSKDAIIEAALGAG--GIRGSLLGGAALLGAGVTAF
Rv3156|M.tuberculosis_H37Rv         AYLAIIGVPPFAGFFSKDAIIEAALGAG--GIRGSLLGGAALLGAGVTAF
MMAR_1472|M.marinum_M               GYLAIIGVPPFAGFFSKDAIIEAALGAG--DTRGYVLGGAALLGAGVTAF
MUL_2470|M.ulcerans_Agy99           GYLAIIGVPPFAGFFSKDAIIEAALGAG--DTRGYVLGGAALLGAGVTAF
MAV_4044|M.avium_104                GYLAIIGVPPFAGFFSKDAIIEAALAAG--GVRGYLLGGAALLGAGVTAF
Mflv_0162|M.gilvum_PYR-GCK          AAASMAALPPFFGFIAKEADFETVLHSPYLGAASPFVLAGIVLGSVLTTV
Mvan_0744|M.vanbaalenii_PYR-1       AAASMAALPPFFGFVAKEADFETVLHSPYLGAASPFVLAGIVLGSVLTTV
MSMEG_0848|M.smegmatis_MC2_155      AVASMAALPPFFGFVAKEADLETVLHSPALGTAAPYVLTGIVVGSVFTTI
TH_4098|M.thermoresistible__bu      AAASMGAIPPFFGFVAKEAVFETMLHSEQLGPSGPWVLAGLVLGSVFTTI
MAB_0636c|M.abscessus_ATCC_199      AAASMAGVPLTLGFVGKELAFATVLHSRVLGSAAPWVLAGIVIGSMFTIT
                                    .  :: .:*   **..*:  : : * :   .  .  :  . ::*: .*  

Mb3180|M.bovis_AF2122/97            YMTRVMLMTFFG--------------------------------------
Rv3156|M.tuberculosis_H37Rv         YMTRVMLMTFFG--------------------------------------
MMAR_1472|M.marinum_M               YMTRVMLMTFFG--------------------------------------
MUL_2470|M.ulcerans_Agy99           YMTRVMLMTFFG--------------------------------------
MAV_4044|M.avium_104                YMTRVMLMTFFG--------------------------------------
Mflv_0162|M.gilvum_PYR-GCK          YSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAGLVFGLWP
Mvan_0744|M.vanbaalenii_PYR-1       YSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAGLLFGLWP
MSMEG_0848|M.smegmatis_MC2_155      YSLRFLWGAFAGKGLSGPSVRVAEMHRPPVNFLLAPAILSAAGLVFGLWP
TH_4098|M.thermoresistible__bu      YSLRFVVGAFGRKGLPGPSRRVEEQHRTPVTFLLAPGVLAAAALVFGVWP
MAB_0636c|M.abscessus_ATCC_199      YSMRFMWGAFARKGLPEPSARVQGMHTPTPAFLTAPALLAVTSVAVGILP
                                    *  *.:  :*                                        

Mb3180|M.bovis_AF2122/97            --------------------------------------------------
Rv3156|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1472|M.marinum_M               --------------------------------------------------
MUL_2470|M.ulcerans_Agy99           --------------------------------------------------
MAV_4044|M.avium_104                --------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK          KPLDTVLSNYSDTVPDPQGYDGDYYLALWHGVNLPLILSALVLLAGVAVC
Mvan_0744|M.vanbaalenii_PYR-1       KPLDTVLRNYSDTVPDPLGYTGDYHLALWHGVNLPLLLSVLVLAAGIGVY
MSMEG_0848|M.smegmatis_MC2_155      KGLDAVLEDYADTVPG----GSTYHLALWHGVGLPLLLSIVVLATGFTVF
TH_4098|M.thermoresistible__bu      SPVDAALHSYAETVPNG-VLLGHYQLALWHGFGPPLLLSAVVIGLGVTVY
MAB_0636c|M.abscessus_ATCC_199      GWLNGTLGSYADPVDA--------HIAIWEGFGIPLLLTAIAFAVGILAF
                                                                                      

Mb3180|M.bovis_AF2122/97            ------------------------------------------EKRWTPGA
Rv3156|M.tuberculosis_H37Rv         ------------------------------------------EKRWTPGA
MMAR_1472|M.marinum_M               ------------------------------------------EKRWAPGA
MUL_2470|M.ulcerans_Agy99           ------------------------------------------EKRWAPGA
MAV_4044|M.avium_104                ------------------------------------------EKRWAPGS
Mflv_0162|M.gilvum_PYR-GCK          VGRGRLR-RARLPYVPLGNADRTYDAVIRGADILSVRLTALTQRGSLPQT
Mvan_0744|M.vanbaalenii_PYR-1       FGRKRLR-RARADFVPLGNADRIYDAVIRGADVLSVRLTALTQRGSLPQT
MSMEG_0848|M.smegmatis_MC2_155      LVRHRLP-KAKSGFLPLGNADRIYDAVIRGLDVVSLRLTASTQRGSLPAT
TH_4098|M.thermoresistible__bu      FLREVLRRRARLPMEVLGNADIVYDKVMRGLDLLAVRTTAITQRGSIPAT
MAB_0636c|M.abscessus_ATCC_199      FSRGRLR-RARLAVNPLGNADRGYDAVLRGADVLSQRLTALTQRGSIPFT
                                                                              ::   * :

Mb3180|M.bovis_AF2122/97            HPHEAPAVMTWPMILLAVGSVFSGGLLAVGGTLRHWLQPVVGSHEEATHA
Rv3156|M.tuberculosis_H37Rv         HPHEAPAVMTWPMILLAVGSVFSGGLLAVGGTLRHWLQPVVGSHEEATHA
MMAR_1472|M.marinum_M               HPHEAPALMTWPMILLAFGSVFSGGLLAMGGTLQRWLEPVVGAHEEATHA
MUL_2470|M.ulcerans_Agy99           HPHEAPALMTWPMILLAFGSVFSGGLLAMGGTLQRWLEPVGGAHEEATHA
MAV_4044|M.avium_104                HPHEAPGLMTWPMILLAVGSVFSGGLFAVGGTLQRWLEPVVGRHEEVTHA
Mflv_0162|M.gilvum_PYR-GCK          QSFILITLVLLPLGVLAFGARDRPEFALWDSPPQVIVGLLMVAAAIAAVV
Mvan_0744|M.vanbaalenii_PYR-1       QSFILVTLVLLPLGVLALGARDRPRFELWDSPPQVVVGLLMVAAALAAVV
MSMEG_0848|M.smegmatis_MC2_155      QSVILLTLVLFPTAALVLGAHNRPDLQLWDSPLQVVVGLLMLAAALGATV
TH_4098|M.thermoresistible__bu      QSVILSVLVLVPVVVLAVGARDRPGFELWDTPLHTVVAAAALAAAAGTTV
MAB_0636c|M.abscessus_ATCC_199      QATILVTLVMLPTIVLAVGDRDQAHLKLWDSPLQGVVGLLILAAAIGATV
                                    :.     ::  *   *..*      :   . . :  :          : .

Mb3180|M.bovis_AF2122/97            LPTWVATTLALGVVAVGIAVAYRMYGTAPIPR------------------
Rv3156|M.tuberculosis_H37Rv         LPTWVATTLALGVVAVGIAVAYRMYGTAPIPR------------------
MMAR_1472|M.marinum_M               LPTWVSTTVALGVVAVGIAVAYRMYGTAAIPR------------------
MUL_2470|M.ulcerans_Agy99           LPTWVSTTVALGVVAVGIVVAYRMYGTAAIPR------------------
MAV_4044|M.avium_104                VPVWISTALALGVVAVGIAVAYRLYATAPIPR------------------
Mflv_0162|M.gilvum_PYR-GCK          MRNRLAAVLMVGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVAFVLVLR
Mvan_0744|M.vanbaalenii_PYR-1       MRNRLAAVLLVGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVAFVLVLR
MSMEG_0848|M.smegmatis_MC2_155      MRNRLAAVLLVGVTGYGCGAIFAFHGAPDLALTQFLVETLVLVIFVLVLR
TH_4098|M.thermoresistible__bu      MRNRLAAALLVGVTGYSCGAIFAFHGAPDLALTQFLVETVTLVIFVLVLR
MAB_0636c|M.abscessus_ATCC_199      MRNRLAAVLLVGITGYGTGTIFALHGAPDLALTQFLVETLTLVIFVLVLR
                                    :   :::.: :*:.. .  . : ::.:. :.                   

Mb3180|M.bovis_AF2122/97            --------------------------VAPVRVSALTAAAR-ADLYGDAFN
Rv3156|M.tuberculosis_H37Rv         --------------------------VAPVRVSALTAAAR-ADLYGDAFN
MMAR_1472|M.marinum_M               --------------------------VAPVRVSVLTTAAR-ADMYADAFN
MUL_2470|M.ulcerans_Agy99           --------------------------VAPVRVSVLTTAAR-ADMYADAFN
MAV_4044|M.avium_104                --------------------------VAPLSVSPLTTAVR-NDFYGDAFN
Mflv_0162|M.gilvum_PYR-GCK          TLPAETSREENTRYRLPRAALALAVGAAVTTLAAYAMAARTGRPIADLLP
Mvan_0744|M.vanbaalenii_PYR-1       TLPAETSRAENTRFRVPRAALAVAVGATVTTLAAFAMAARTGRPIAELLP
MSMEG_0848|M.smegmatis_MC2_155      TLPAEADAANINKNRLPRALLALSVGAAVTTLTVYAMAARTGPGVAVLLP
TH_4098|M.thermoresistible__bu      SLPPETDQAQISRFRWPRAVLALSVGFSLTTLAVFALAARDGMAVAALLP
MAB_0636c|M.abscessus_ATCC_199      ALPAESDIQQANRFRLPRAVLAIAVGCTVTALGVYAMAARRDRPIADLLP
                                                               :   :   : *.*     .  : 

Mb3180|M.bovis_AF2122/97            EEVFMRPGAQLTNAVVAVDDAGVDGSVNALATLVSQTSNR----------
Rv3156|M.tuberculosis_H37Rv         EEVFMRPGAQLTNAVVAVDDAGVDGSVNALATLVSQTSNR----------
MMAR_1472|M.marinum_M               EEVFMRPGAQLTDAVVEVDNAGVDGSVNALAGLVSMTSNR----------
MUL_2470|M.ulcerans_Agy99           EEVFMRPGAQLTDAVVEVDNAGVDGSVNALAGLVSMTSNR----------
MAV_4044|M.avium_104                EEVFMRPGAQLTHALVEVDDAGVDGSVNALAALVSATSNR----------
Mflv_0162|M.gilvum_PYR-GCK          EAAYVLGHGSNTVNVLLVDIRAWDTMGEISVLLVAATGVASMVFRSRRFG
Mvan_0744|M.vanbaalenii_PYR-1       EAAYVLGHGSNTVNVILVDIRAWDTMGEVSVLLVAATGVASMVFRSRRFG
MSMEG_0848|M.smegmatis_MC2_155      DAAYYRGHGSNTVNVLLVDIRAWDTMGEVMVLLVAATGVASLVFRHRRFG
TH_4098|M.thermoresistible__bu      DAAYHLGHGANTVNVILVDIRAWDTMGEIMVLVVAATGVASMVFRHRRFG
MAB_0636c|M.abscessus_ATCC_199      QAAYQRGHGANTVNVLLVDIRAWDTLGEISVLLVAATGVASLMFRHRRFG
                                    : .:    .  *  :: **  . *   :  . :*: *.            

Mb3180|M.bovis_AF2122/97            --------------------------------LRQMQTGFARNYALSMLV
Rv3156|M.tuberculosis_H37Rv         --------------------------------LRQMQTGFARNYALSMLV
MMAR_1472|M.marinum_M               --------------------------------LRRMQTGFARNYALSMLA
MUL_2470|M.ulcerans_Agy99           --------------------------------LRLMQTGFARNYALSMLA
MAV_4044|M.avium_104                --------------------------------LRGLQTGFARNYALSMLT
Mflv_0162|M.gilvum_PYR-GCK          AAPRVS-DAGQPDIGLLPSSYNISPAAGEITWLRGSELRDPRHRSLVLEV
Mvan_0744|M.vanbaalenii_PYR-1       AAPRVS-DAGQPDIGRLPTSFNTSPAAGDIIWLRGSGLRDPRHRSLVLEV
MSMEG_0848|M.smegmatis_MC2_155      AAPRVSTAVGQPDIGPVAA---YSPAAGDVTWLRGSELRDPRHRSLILEV
TH_4098|M.thermoresistible__bu      SPPRVS-DAGQPDIGRIAQFVDISPAVGDITWLRGSEFRDPQHRSLVLEV
MAB_0636c|M.abscessus_ATCC_199      RAPRVGDAAGQPDV-----------VVASGIWLRGSELRDPKHRSLVLEV
                                                                    **      .:: :* : .

Mb3180|M.bovis_AF2122/97            GAVLVAAALLVVQLW-----------------------------------
Rv3156|M.tuberculosis_H37Rv         GAVLVAAALLVVQLW-----------------------------------
MMAR_1472|M.marinum_M               GAVLVAAVLLAVQLW-----------------------------------
MUL_2470|M.ulcerans_Agy99           GAVLVAAVLLAVQLW-----------------------------------
MAV_4044|M.avium_104                GAVLVIALILAVRLW-----------------------------------
Mflv_0162|M.gilvum_PYR-GCK          ATRLIFPVMMVLSAYFFFAGHNVPGGGFAGGLMAGLALVLRYLAGGRYEL
Mvan_0744|M.vanbaalenii_PYR-1       ATRLIFPVMMVLSAYFFFAGHNVPGGGFAGGLMAGLALVLRYLAGGRYEL
MSMEG_0848|M.smegmatis_MC2_155      ATRLIFPLIMVLSAYFFFAGHNTPGGGFAGGLVAGLALVLRYLAGGRYEL
TH_4098|M.thermoresistible__bu      ATRIIFPLMMVLSAYFFFAGHNSPGGGFAGGLTAGLAVVLRYIAGGRYEL
MAB_0636c|M.abscessus_ATCC_199      ATRLIFPLVMVLSFYFFFAGHNVPGGGFAGGLTAGLALVLRYLAGGRYEL
                                    .: :: . ::.:  :                                   

Mb3180|M.bovis_AF2122/97            --------------------------------------------------
Rv3156|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1472|M.marinum_M               --------------------------------------------------
MUL_2470|M.ulcerans_Agy99           --------------------------------------------------
MAV_4044|M.avium_104                --------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK          GETLPLDAGKILGAGLALSAGTAVASLLLGAPALSSAVIEFDVPVLGSVK
Mvan_0744|M.vanbaalenii_PYR-1       GETLPLDAGKILGAGLTLAAGTAAASLFLGAPVLSSALIQVDLPVLGTVK
MSMEG_0848|M.smegmatis_MC2_155      GETLPLDAGKILGTGLGLSAGTAVASLLLGAPALSSAVVQLDVPVIGPIK
TH_4098|M.thermoresistible__bu      GETIPLDAGKVLGAGLTLAAGTAATSLLLGAPALSSALIELTLPVLGQVT
MAB_0636c|M.abscessus_ATCC_199      GETLPFDAGKILGLGLAFSGGAALSSMLLGAPVLSSATIQFDMLGFGHVK
                                                                                      

Mb3180|M.bovis_AF2122/97            -------------------------------------------------
Rv3156|M.tuberculosis_H37Rv         -------------------------------------------------
MMAR_1472|M.marinum_M               -------------------------------------------------
MUL_2470|M.ulcerans_Agy99           -------------------------------------------------
MAV_4044|M.avium_104                -------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK          FVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQRR-QTDRTVRQR
Mvan_0744|M.vanbaalenii_PYR-1       FVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQSRPQTGRMARQR
MSMEG_0848|M.smegmatis_MC2_155      FVTALFFDLGVYLIVVGLVLDVLRSLGARVDVELAESGQPQKAAA----
TH_4098|M.thermoresistible__bu      FMTTLFFDLGVYLIVVGLVLDVLRSLGARLDVELAGPAPARAVAKPR--
MAB_0636c|M.abscessus_ATCC_199      IVTAIFFDLGVYLVVVGLVLDVLRSLGARLDVELEESPRTRAGARTS--