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LAILAAHAVATLLAPLLVYRWGRMAFYPLALVPLGSLFWVVLNWPAKGQSHTVDVSWVPELSMDITLRFD ALAAVMSVLVLAIGALVLFYCADYFHHHDGHKEKRLPSFAAELVAFSGAMFGLVTSDNMLVLYVFWEITT VLSFLLVGHYAERATSRRSAMQALLVTTFGGLAMLVGIVVIGNIAGTFLLSELIADPPTGLAASVAVVLI LVGALSKSAIVPMHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPEWRPTVVTLGLLTML LAGWRAIREYDLKLILAFGTVSQLGFITVMVGVGGSEMMLAGLAMLCAHAMFKAALFMTVGIIDHATGTR DIRRLAWLGDRSRPLLIVGCAAAASMAALPPFFGFVAKEADFETVLHSPYLGAASPFVLAGIVLGSVLTT VYSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAGLLFGLWPKPLDTVLRNYSDTVPDPLG YTGDYHLALWHGVNLPLLLSVLVLAAGIGVYFGRKRLRRARADFVPLGNADRIYDAVIRGADVLSVRLTA LTQRGSLPQTQSFILVTLVLLPLGVLALGARDRPRFELWDSPPQVVVGLLMVAAALAAVVMRNRLAAVLL VGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVAFVLVLRTLPAETSRAENTRFRVPRAALAVAVGATVT TLAAFAMAARTGRPIAELLPEAAYVLGHGSNTVNVILVDIRAWDTMGEVSVLLVAATGVASMVFRSRRFG AAPRVSDAGQPDIGRLPTSFNTSPAAGDIIWLRGSGLRDPRHRSLVLEVATRLIFPVMMVLSAYFFFAGH NVPGGGFAGGLMAGLALVLRYLAGGRYELGETLPLDAGKILGAGLTLAAGTAAASLFLGAPVLSSALIQV DLPVLGTVKFVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQSRPQTGRMARQR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_0744 | - | - | 100% (969) | putative monovalent cation/H+ antiporter subunit A |
M. vanbaalenii PYR-1 | Mvan_1874 | - | 7e-48 | 30.59% (559) | NADH dehydrogenase subunit L |
M. vanbaalenii PYR-1 | Mvan_0742 | - | 8e-33 | 26.55% (467) | putative monovalent cation/H+ antiporter subunit D |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3180 | nuoL | 4e-45 | 30.54% (429) | NADH dehydrogenase subunit L |
M. gilvum PYR-GCK | Mflv_0162 | - | 0.0 | 91.64% (969) | putative monovalent cation/H+ antiporter subunit A |
M. tuberculosis H37Rv | Rv3156 | nuoL | 3e-45 | 30.54% (429) | NADH dehydrogenase subunit L |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0636c | - | 0.0 | 70.23% (964) | putative monovalent cation/H+ antiporter subunit A |
M. marinum M | MMAR_1472 | nuoL | 5e-47 | 31.21% (423) | NADH dehydrogenase I (chain L) NuoL (NADH- ubiquinone |
M. avium 104 | MAV_4044 | - | 3e-50 | 31.38% (478) | NADH dehydrogenase subunit L |
M. smegmatis MC2 155 | MSMEG_0848 | - | 0.0 | 79.42% (962) | putative monovalent cation/H+ antiporter subunit A |
M. thermoresistible (build 8) | TH_4098 | - | 0.0 | 76.57% (956) | PUTATIVE NADH dehydrogenase (quinone) |
M. ulcerans Agy99 | MUL_2470 | nuoL | 2e-47 | 31.44% (423) | NADH dehydrogenase subunit L |
CLUSTAL 2.0.9 multiple sequence alignment Mb3180|M.bovis_AF2122/97 MTTSLG-------THYTWLLVALPLAGAAILLFGGRRTDAWGHLLGCAAA Rv3156|M.tuberculosis_H37Rv MTTSLG-------THYTWLLVALPLAGAAILLFGGRRTDAWGHLLGCAAA MMAR_1472|M.marinum_M MTNFLG-------TQHTWLLVALPLAGAAILLFGGRRTDAWGHWLGCAAA MUL_2470|M.ulcerans_Agy99 MTNFLG-------TQHTWLLVALPLAGAAILLFGGRRTDAWGHWLGCAAA MAV_4044|M.avium_104 MTRTYSKAEHANMTHYTPLLVALPLAGAAILLFGGRRTDRWGHWLGCATA Mvan_0744|M.vanbaalenii_PYR-1 -------------------MLAILAAHAVATLLAPLLVYRWGRMAFYPLA Mflv_0162|M.gilvum_PYR-GCK -------------------MLAILAAHAAAALLAPLLVYRWGRLAFYPLA MSMEG_0848|M.smegmatis_MC2_155 -------------------MLAVLLAHAVATALAPLMVARWGRMAFFPLS TH_4098|M.thermoresistible__bu -------------------MLAILIAHAIATALAPLLVYRWDRKAFYPLA MAB_0636c|M.abscessus_ATCC_199 -------------------MLAILLAHALAAAVAPLLVARMGRLAFYPLA ::*: * * .. . .: . : Mb3180|M.bovis_AF2122/97 LAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGGLQVDFGLQIDQLSM Rv3156|M.tuberculosis_H37Rv LAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGGLQVDFGLQIDQLSM MMAR_1472|M.marinum_M LASFGVGATMLADLVGRSADDRLIHQTVFTWMPVSQLQVDFGLQIDQLSI MUL_2470|M.ulcerans_Agy99 LASFGVGATMLADLVGRSADDRLIHQTVFTWMPVSQLQVDFGLQIDQLSI MAV_4044|M.avium_104 VAAFVVGVGLLDELLGRPADQRAIHERVFSWIPVGQLQVDLGLQIDQLSV Mvan_0744|M.vanbaalenii_PYR-1 LVPLGSLFWVVLNWPAKG----QSHTVDVSWVP--ELSMDITLRFDALAA Mflv_0162|M.gilvum_PYR-GCK LVPLGSLVWVVLNWPAKG----QSRNVDVPWVP--GLSMDITLRFDALAA MSMEG_0848|M.smegmatis_MC2_155 LVPLGSLVWVALNWPSPD----NIPTVHVSWVP--ELWMDFTLRFDALAA TH_4098|M.thermoresistible__bu LVPLGSLVWVALNWPRDG----HVPTTDIEWVP--ELAMDVNLRFDSLAA MAB_0636c|M.abscessus_ATCC_199 LVPFGSLIWVLARWPGNS----PGVRVDIPWVP--ELAMDIALRFDALAA :..: : . *:* * :*. *::* *: Mb3180|M.bovis_AF2122/97 CFVLLISGVGSLIHIYSVGYMAEDPDRRR-----FFGYLNLFLASMLLLV Rv3156|M.tuberculosis_H37Rv CFVLLISGVGSLIHIYSVGYMAEDPDRRR-----FFGYLNLFLASMLLLV MMAR_1472|M.marinum_M CFVLLITGVGSLIHIYSVAYMAEDPDRRR-----FFGYLNLFLASMLLLV MUL_2470|M.ulcerans_Agy99 CFVLLITGVGSLIHIYSVAYMAEDPDRRR-----FFGYLNLFLASMLLLV MAV_4044|M.avium_104 CFVLLITGVGSLIHIYSVAYMAEDADRRR-----FFGYLNLFLASMLLLV Mvan_0744|M.vanbaalenii_PYR-1 VMSVLVLAIGALVLFYCADYFHHHDGHKEKRLPSFAAELVAFSGAMFGLV Mflv_0162|M.gilvum_PYR-GCK IMSVLVLAIGALVLFYCADYFRHHDGRIEKRLPSFAAELVAFSGAMFGLV MSMEG_0848|M.smegmatis_MC2_155 IMSVLVLAIGALVLFYCAHYFHHHDGRMEKRLPSFAAELVAFSGAMFGLV TH_4098|M.thermoresistible__bu VMSVLVLAIGALVLFYCGDYFHHHDGRREKRLPSFAAELVAFSGAMFGLV MAB_0636c|M.abscessus_ATCC_199 IMSVLVLGIGSLVLFYCASYFRHRDGHTEPRLPSFAAELVAFSGAMFGLV : :*: .:*:*: :*. *: . .: . * . * * .:*: ** Mb3180|M.bovis_AF2122/97 VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL Rv3156|M.tuberculosis_H37Rv VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL MMAR_1472|M.marinum_M VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL MUL_2470|M.ulcerans_Agy99 VADNYVLLYVGWEGVGLASYLLIGFWYHKASAATAAKKAFVMNRVGDAGL MAV_4044|M.avium_104 IADNYVVLYVGWEGVGLASYLLIGFWYHKPTAATAAKKAFVMNRVGDAGL Mvan_0744|M.vanbaalenii_PYR-1 TSDNMLVLYVFWEITTVLSFLLVGHYAERATSRRSAMQALLVTTFGGLAM Mflv_0162|M.gilvum_PYR-GCK TSDNMLVLYVFWEITTVLSFLLVGHYAERATTRRAAMQALLVTTFGGLAM MSMEG_0848|M.smegmatis_MC2_155 VSDNMLVLYIFWETTTVLSFLLVGHYAERATSRRAATQALLVTTFGGLAM TH_4098|M.thermoresistible__bu VSDNMLVLYVFWEITTVLSFLLVGHYAERATSRRAATQALLVTTFGGLAM MAB_0636c|M.abscessus_ATCC_199 ISDNLLVLYIFWELTTVLSFLLVGHYAERLASRRAAVQALLVTTAGGLAM :** ::**: ** . : *:**:*.: .: :: :* :*:::. *. .: Mb3180|M.bovis_AF2122/97 AVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACAKSAQVP Rv3156|M.tuberculosis_H37Rv AVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACAKSAQVP MMAR_1472|M.marinum_M ALGMFVMFSTFGTLSYAGVFAGAPAASRGALTAMGLLLLLGACAKSAQVP MUL_2470|M.ulcerans_Agy99 ALGMFVMFSTFGTLSYAGVFAGAPAASRGALTAMGLLLLLGACAKSAQVP MAV_4044|M.avium_104 ALGMFLMFSTFGTLSYAGVFAGAPAAGRGALTAMGLLLLLGACAKSAQVP Mvan_0744|M.vanbaalenii_PYR-1 LVGIVVIGNIAGTFLLSELIADPPTG--LAASVAVVLILVGALSKSAIVP Mflv_0162|M.gilvum_PYR-GCK LVGIVVIGNIADTFLLSELIANPPTG--VAASVALVLILVGALSKSAIVP MSMEG_0848|M.smegmatis_MC2_155 LTGIVVLGNMAGTYLLSELIAAPPTG--TAASVGIALILIGALSKSAIVP TH_4098|M.thermoresistible__bu LAGIVVLGNLAGTYLLSELIAAPPTG--VAATVAVVLVLVGALSKSAIVP MAB_0636c|M.abscessus_ATCC_199 LVGVIVLGHVGGSFLLSDLIANPPTG--LAASVGLVLVLIGALSKSAIVP *:.: .: : ::* *:. . :. *:*:** :*** ** Mb3180|M.bovis_AF2122/97 LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPTAQLAVV Rv3156|M.tuberculosis_H37Rv LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPTAQLAVV MMAR_1472|M.marinum_M LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNPLYNLAPDAQLAVV MUL_2470|M.ulcerans_Agy99 LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNLLYNLAPDAQLAVV MAV_4044|M.avium_104 LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNPLYNLSPDAQLAVV Mvan_0744|M.vanbaalenii_PYR-1 MHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPEWRPTVV Mflv_0162|M.gilvum_PYR-GCK LHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPEWRPTVV MSMEG_0848|M.smegmatis_MC2_155 MHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADTAFWRPMVI TH_4098|M.thermoresistible__bu LHFWLPGAMAAPSPVSAYLHAAAMVKAGVYLVARMTPGFADFSVWRPMAI MAB_0636c|M.abscessus_ATCC_199 LHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLLARMSPGFAEAAPWRPVVL :: ** .** .*:**** :***:**.**:**:.* : . : .: Mb3180|M.bovis_AF2122/97 IVGAVTLLYGAIIGCAKDDIKRALAASTISQIGYMVLAAGLGPAGYAFA- Rv3156|M.tuberculosis_H37Rv IVGAVTLLFGAIIGCAKDDIKRALAASTISQIGYMVLAAGLGPAGYAFA- MMAR_1472|M.marinum_M VVGTVTLLLGAVIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA- MUL_2470|M.ulcerans_Agy99 VVGTVTLLLGGVIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA- MAV_4044|M.avium_104 IVGAVTLLLGAFIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA- Mvan_0744|M.vanbaalenii_PYR-1 TLGLLTMLLAGWRAIREYDLKLILAFGTVSQLGFITVMVGVGGSEMMLAG Mflv_0162|M.gilvum_PYR-GCK GLGLLTMLLAGWRAIREYDLKLILAFGTVSQLGFITIMVGVGGSEMMLAG MSMEG_0848|M.smegmatis_MC2_155 GLGLLTMLLAGWRAVREYDLKLILAFGTVSQLGLITVMVGAGGPDMMLAG TH_4098|M.thermoresistible__bu VLGLATLLLAGWRAIREYDLKLILAFGTVSQLGLITVLVSAGSGDLMLAG MAB_0636c|M.abscessus_ATCC_199 VLGIATMILAGWRALREYDLKLILAFGTVSQLGFLVVLTGTGDPDILLAG :* *:: .. . : *:* ** .*:**:* :.: .. * :* Mb3180|M.bovis_AF2122/97 IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFATFGL Rv3156|M.tuberculosis_H37Rv IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFATFGL MMAR_1472|M.marinum_M IMHLLTHGFFKAGLFLGSGSVIHAMHEEQDMRRYGGLRAALPVTFVTFGL MUL_2470|M.ulcerans_Agy99 IMHLLTHGFFKAGLFLGSGSVIHAIHEEQDMRRYGGLRAALPVTFVTFGL MAV_4044|M.avium_104 IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFVTFGL Mvan_0744|M.vanbaalenii_PYR-1 LAMLCAHAMFKAALFMTVGIIDHATG-TRDIRRLAWLGDRSRPLLIVGCA Mflv_0162|M.gilvum_PYR-GCK LAMLCAHAMFKAALFMVVGIIDHATG-TRDIRRLAWLGDRSKPLLIIGCA MSMEG_0848|M.smegmatis_MC2_155 LAMLIAHAMFKASLFMVVGVIDHATG-TRDIRRLAGLGRAHRPLLIIALG TH_4098|M.thermoresistible__bu LAMLVAHAMFKAALFMVVGIIDHTTG-TRDIRRLAWLGNRNKPLLVIAVA MAB_0636c|M.abscessus_ATCC_199 LVMLCAHALFKAALFMVVGIIDHTVG-TRDIRKLAWLGNRQPPLLVIAGI : * :*.:***.**: * : *: :*:*: . * : Mb3180|M.bovis_AF2122/97 AYLAIIGVPPFAGFFSKDAIIEAALGAG--GIRGSLLGGAALLGAGVTAF Rv3156|M.tuberculosis_H37Rv AYLAIIGVPPFAGFFSKDAIIEAALGAG--GIRGSLLGGAALLGAGVTAF MMAR_1472|M.marinum_M GYLAIIGVPPFAGFFSKDAIIEAALGAG--DTRGYVLGGAALLGAGVTAF MUL_2470|M.ulcerans_Agy99 GYLAIIGVPPFAGFFSKDAIIEAALGAG--DTRGYVLGGAALLGAGVTAF MAV_4044|M.avium_104 GYLAIIGVPPFAGFFSKDAIIEAALAAG--GVRGYLLGGAALLGAGVTAF Mvan_0744|M.vanbaalenii_PYR-1 AAASMAALPPFFGFVAKEADFETVLHSPYLGAASPFVLAGIVLGSVLTTV Mflv_0162|M.gilvum_PYR-GCK AAASMAALPPFFGFIAKEADFETVLHSPYLGAASPFVLAGIVLGSVLTTV MSMEG_0848|M.smegmatis_MC2_155 AVASMAALPPFFGFVAKEADLETVLHSPALGTAAPYVLTGIVVGSVFTTI TH_4098|M.thermoresistible__bu AAASMGAIPPFFGFVAKEAVFETMLHSEQLGPSGPWVLAGLVLGSVFTTI MAB_0636c|M.abscessus_ATCC_199 AAASMAGVPLTLGFVGKELAFATVLHSRVLGSAAPWVLAGIVIGSMFTIT . :: .:* **..*: : : * : . . : . ::*: .* Mb3180|M.bovis_AF2122/97 YMTRVMLMTFFG-------------------------------------- Rv3156|M.tuberculosis_H37Rv YMTRVMLMTFFG-------------------------------------- MMAR_1472|M.marinum_M YMTRVMLMTFFG-------------------------------------- MUL_2470|M.ulcerans_Agy99 YMTRVMLMTFFG-------------------------------------- MAV_4044|M.avium_104 YMTRVMLMTFFG-------------------------------------- Mvan_0744|M.vanbaalenii_PYR-1 YSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAGLLFGLWP Mflv_0162|M.gilvum_PYR-GCK YSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAGLVFGLWP MSMEG_0848|M.smegmatis_MC2_155 YSLRFLWGAFAGKGLSGPSVRVAEMHRPPVNFLLAPAILSAAGLVFGLWP TH_4098|M.thermoresistible__bu YSLRFVVGAFGRKGLPGPSRRVEEQHRTPVTFLLAPGVLAAAALVFGVWP MAB_0636c|M.abscessus_ATCC_199 YSMRFMWGAFARKGLPEPSARVQGMHTPTPAFLTAPALLAVTSVAVGILP * *.: :* Mb3180|M.bovis_AF2122/97 -------------------------------------------------- Rv3156|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1472|M.marinum_M -------------------------------------------------- MUL_2470|M.ulcerans_Agy99 -------------------------------------------------- MAV_4044|M.avium_104 -------------------------------------------------- Mvan_0744|M.vanbaalenii_PYR-1 KPLDTVLRNYSDTVPDPLGYTGDYHLALWHGVNLPLLLSVLVLAAGIGVY Mflv_0162|M.gilvum_PYR-GCK KPLDTVLSNYSDTVPDPQGYDGDYYLALWHGVNLPLILSALVLLAGVAVC MSMEG_0848|M.smegmatis_MC2_155 KGLDAVLEDYADTVPG----GSTYHLALWHGVGLPLLLSIVVLATGFTVF TH_4098|M.thermoresistible__bu SPVDAALHSYAETVPNG-VLLGHYQLALWHGFGPPLLLSAVVIGLGVTVY MAB_0636c|M.abscessus_ATCC_199 GWLNGTLGSYADPVDA--------HIAIWEGFGIPLLLTAIAFAVGILAF Mb3180|M.bovis_AF2122/97 ------------------------------------------EKRWTPGA Rv3156|M.tuberculosis_H37Rv ------------------------------------------EKRWTPGA MMAR_1472|M.marinum_M ------------------------------------------EKRWAPGA MUL_2470|M.ulcerans_Agy99 ------------------------------------------EKRWAPGA MAV_4044|M.avium_104 ------------------------------------------EKRWAPGS Mvan_0744|M.vanbaalenii_PYR-1 FGRKRLR-RARADFVPLGNADRIYDAVIRGADVLSVRLTALTQRGSLPQT Mflv_0162|M.gilvum_PYR-GCK VGRGRLR-RARLPYVPLGNADRTYDAVIRGADILSVRLTALTQRGSLPQT MSMEG_0848|M.smegmatis_MC2_155 LVRHRLP-KAKSGFLPLGNADRIYDAVIRGLDVVSLRLTASTQRGSLPAT TH_4098|M.thermoresistible__bu FLREVLRRRARLPMEVLGNADIVYDKVMRGLDLLAVRTTAITQRGSIPAT MAB_0636c|M.abscessus_ATCC_199 FSRGRLR-RARLAVNPLGNADRGYDAVLRGADVLSQRLTALTQRGSIPFT :: * : Mb3180|M.bovis_AF2122/97 HPHEAPAVMTWPMILLAVGSVFSGGLLAVGGTLRHWLQPVVGSHEEATHA Rv3156|M.tuberculosis_H37Rv HPHEAPAVMTWPMILLAVGSVFSGGLLAVGGTLRHWLQPVVGSHEEATHA MMAR_1472|M.marinum_M HPHEAPALMTWPMILLAFGSVFSGGLLAMGGTLQRWLEPVVGAHEEATHA MUL_2470|M.ulcerans_Agy99 HPHEAPALMTWPMILLAFGSVFSGGLLAMGGTLQRWLEPVGGAHEEATHA MAV_4044|M.avium_104 HPHEAPGLMTWPMILLAVGSVFSGGLFAVGGTLQRWLEPVVGRHEEVTHA Mvan_0744|M.vanbaalenii_PYR-1 QSFILVTLVLLPLGVLALGARDRPRFELWDSPPQVVVGLLMVAAALAAVV Mflv_0162|M.gilvum_PYR-GCK QSFILITLVLLPLGVLAFGARDRPEFALWDSPPQVIVGLLMVAAAIAAVV MSMEG_0848|M.smegmatis_MC2_155 QSVILLTLVLFPTAALVLGAHNRPDLQLWDSPLQVVVGLLMLAAALGATV TH_4098|M.thermoresistible__bu QSVILSVLVLVPVVVLAVGARDRPGFELWDTPLHTVVAAAALAAAAGTTV MAB_0636c|M.abscessus_ATCC_199 QATILVTLVMLPTIVLAVGDRDQAHLKLWDSPLQGVVGLLILAAAIGATV :. :: * *..* : . . : : : . Mb3180|M.bovis_AF2122/97 LPTWVATTLALGVVAVGIAVAYRMYGTAPIPR------------------ Rv3156|M.tuberculosis_H37Rv LPTWVATTLALGVVAVGIAVAYRMYGTAPIPR------------------ MMAR_1472|M.marinum_M LPTWVSTTVALGVVAVGIAVAYRMYGTAAIPR------------------ MUL_2470|M.ulcerans_Agy99 LPTWVSTTVALGVVAVGIVVAYRMYGTAAIPR------------------ MAV_4044|M.avium_104 VPVWISTALALGVVAVGIAVAYRLYATAPIPR------------------ Mvan_0744|M.vanbaalenii_PYR-1 MRNRLAAVLLVGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVAFVLVLR Mflv_0162|M.gilvum_PYR-GCK MRNRLAAVLMVGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVAFVLVLR MSMEG_0848|M.smegmatis_MC2_155 MRNRLAAVLLVGVTGYGCGAIFAFHGAPDLALTQFLVETLVLVIFVLVLR TH_4098|M.thermoresistible__bu MRNRLAAALLVGVTGYSCGAIFAFHGAPDLALTQFLVETVTLVIFVLVLR MAB_0636c|M.abscessus_ATCC_199 MRNRLAAVLLVGITGYGTGTIFALHGAPDLALTQFLVETLTLVIFVLVLR : :::.: :*:.. . . : ::.:. :. Mb3180|M.bovis_AF2122/97 --------------------------VAPVRVSALTAAAR-ADLYGDAFN Rv3156|M.tuberculosis_H37Rv --------------------------VAPVRVSALTAAAR-ADLYGDAFN MMAR_1472|M.marinum_M --------------------------VAPVRVSVLTTAAR-ADMYADAFN MUL_2470|M.ulcerans_Agy99 --------------------------VAPVRVSVLTTAAR-ADMYADAFN MAV_4044|M.avium_104 --------------------------VAPLSVSPLTTAVR-NDFYGDAFN Mvan_0744|M.vanbaalenii_PYR-1 TLPAETSRAENTRFRVPRAALAVAVGATVTTLAAFAMAARTGRPIAELLP Mflv_0162|M.gilvum_PYR-GCK TLPAETSREENTRYRLPRAALALAVGAAVTTLAAYAMAARTGRPIADLLP MSMEG_0848|M.smegmatis_MC2_155 TLPAEADAANINKNRLPRALLALSVGAAVTTLTVYAMAARTGPGVAVLLP TH_4098|M.thermoresistible__bu SLPPETDQAQISRFRWPRAVLALSVGFSLTTLAVFALAARDGMAVAALLP MAB_0636c|M.abscessus_ATCC_199 ALPAESDIQQANRFRLPRAVLAIAVGCTVTALGVYAMAARRDRPIADLLP : : : *.* . : Mb3180|M.bovis_AF2122/97 EEVFMRPGAQLTNAVVAVDDAGVDGSVNALATLVSQTSNR---------- Rv3156|M.tuberculosis_H37Rv EEVFMRPGAQLTNAVVAVDDAGVDGSVNALATLVSQTSNR---------- MMAR_1472|M.marinum_M EEVFMRPGAQLTDAVVEVDNAGVDGSVNALAGLVSMTSNR---------- MUL_2470|M.ulcerans_Agy99 EEVFMRPGAQLTDAVVEVDNAGVDGSVNALAGLVSMTSNR---------- MAV_4044|M.avium_104 EEVFMRPGAQLTHALVEVDDAGVDGSVNALAALVSATSNR---------- Mvan_0744|M.vanbaalenii_PYR-1 EAAYVLGHGSNTVNVILVDIRAWDTMGEVSVLLVAATGVASMVFRSRRFG Mflv_0162|M.gilvum_PYR-GCK EAAYVLGHGSNTVNVLLVDIRAWDTMGEISVLLVAATGVASMVFRSRRFG MSMEG_0848|M.smegmatis_MC2_155 DAAYYRGHGSNTVNVLLVDIRAWDTMGEVMVLLVAATGVASLVFRHRRFG TH_4098|M.thermoresistible__bu DAAYHLGHGANTVNVILVDIRAWDTMGEIMVLVVAATGVASMVFRHRRFG MAB_0636c|M.abscessus_ATCC_199 QAAYQRGHGANTVNVLLVDIRAWDTLGEISVLLVAATGVASLMFRHRRFG : .: . * :: ** . * : . :*: *. Mb3180|M.bovis_AF2122/97 --------------------------------LRQMQTGFARNYALSMLV Rv3156|M.tuberculosis_H37Rv --------------------------------LRQMQTGFARNYALSMLV MMAR_1472|M.marinum_M --------------------------------LRRMQTGFARNYALSMLA MUL_2470|M.ulcerans_Agy99 --------------------------------LRLMQTGFARNYALSMLA MAV_4044|M.avium_104 --------------------------------LRGLQTGFARNYALSMLT Mvan_0744|M.vanbaalenii_PYR-1 AAPRVS-DAGQPDIGRLPTSFNTSPAAGDIIWLRGSGLRDPRHRSLVLEV Mflv_0162|M.gilvum_PYR-GCK AAPRVS-DAGQPDIGLLPSSYNISPAAGEITWLRGSELRDPRHRSLVLEV MSMEG_0848|M.smegmatis_MC2_155 AAPRVSTAVGQPDIGPVAA---YSPAAGDVTWLRGSELRDPRHRSLILEV TH_4098|M.thermoresistible__bu SPPRVS-DAGQPDIGRIAQFVDISPAVGDITWLRGSEFRDPQHRSLVLEV MAB_0636c|M.abscessus_ATCC_199 RAPRVGDAAGQPDV-----------VVASGIWLRGSELRDPKHRSLVLEV ** .:: :* : . Mb3180|M.bovis_AF2122/97 GAVLVAAALLVVQLW----------------------------------- Rv3156|M.tuberculosis_H37Rv GAVLVAAALLVVQLW----------------------------------- MMAR_1472|M.marinum_M GAVLVAAVLLAVQLW----------------------------------- MUL_2470|M.ulcerans_Agy99 GAVLVAAVLLAVQLW----------------------------------- MAV_4044|M.avium_104 GAVLVIALILAVRLW----------------------------------- Mvan_0744|M.vanbaalenii_PYR-1 ATRLIFPVMMVLSAYFFFAGHNVPGGGFAGGLMAGLALVLRYLAGGRYEL Mflv_0162|M.gilvum_PYR-GCK ATRLIFPVMMVLSAYFFFAGHNVPGGGFAGGLMAGLALVLRYLAGGRYEL MSMEG_0848|M.smegmatis_MC2_155 ATRLIFPLIMVLSAYFFFAGHNTPGGGFAGGLVAGLALVLRYLAGGRYEL TH_4098|M.thermoresistible__bu ATRIIFPLMMVLSAYFFFAGHNSPGGGFAGGLTAGLAVVLRYIAGGRYEL MAB_0636c|M.abscessus_ATCC_199 ATRLIFPLVMVLSFYFFFAGHNVPGGGFAGGLTAGLALVLRYLAGGRYEL .: :: . ::.: : Mb3180|M.bovis_AF2122/97 -------------------------------------------------- Rv3156|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1472|M.marinum_M -------------------------------------------------- MUL_2470|M.ulcerans_Agy99 -------------------------------------------------- MAV_4044|M.avium_104 -------------------------------------------------- Mvan_0744|M.vanbaalenii_PYR-1 GETLPLDAGKILGAGLTLAAGTAAASLFLGAPVLSSALIQVDLPVLGTVK Mflv_0162|M.gilvum_PYR-GCK GETLPLDAGKILGAGLALSAGTAVASLLLGAPALSSAVIEFDVPVLGSVK MSMEG_0848|M.smegmatis_MC2_155 GETLPLDAGKILGTGLGLSAGTAVASLLLGAPALSSAVVQLDVPVIGPIK TH_4098|M.thermoresistible__bu GETIPLDAGKVLGAGLTLAAGTAATSLLLGAPALSSALIELTLPVLGQVT MAB_0636c|M.abscessus_ATCC_199 GETLPFDAGKILGLGLAFSGGAALSSMLLGAPVLSSATIQFDMLGFGHVK Mb3180|M.bovis_AF2122/97 ------------------------------------------------- Rv3156|M.tuberculosis_H37Rv ------------------------------------------------- MMAR_1472|M.marinum_M ------------------------------------------------- MUL_2470|M.ulcerans_Agy99 ------------------------------------------------- MAV_4044|M.avium_104 ------------------------------------------------- Mvan_0744|M.vanbaalenii_PYR-1 FVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQSRPQTGRMARQR Mflv_0162|M.gilvum_PYR-GCK FVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQRR-QTDRTVRQR MSMEG_0848|M.smegmatis_MC2_155 FVTALFFDLGVYLIVVGLVLDVLRSLGARVDVELAESGQPQKAAA---- TH_4098|M.thermoresistible__bu FMTTLFFDLGVYLIVVGLVLDVLRSLGARLDVELAGPAPARAVAKPR-- MAB_0636c|M.abscessus_ATCC_199 IVTAIFFDLGVYLVVVGLVLDVLRSLGARLDVELEESPRTRAGARTS--