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MLAILAAHAAAALLAPLLVYRWGRLAFYPLALVPLGSLVWVVLNWPAKGQSRNVDVPWVPGLSMDITLRF DALAAIMSVLVLAIGALVLFYCADYFRHHDGRIEKRLPSFAAELVAFSGAMFGLVTSDNMLVLYVFWEIT TVLSFLLVGHYAERATTRRAAMQALLVTTFGGLAMLVGIVVIGNIADTFLLSELIANPPTGVAASVALVL ILVGALSKSAIVPLHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPEWRPTVVGLGLLTM LLAGWRAIREYDLKLILAFGTVSQLGFITIMVGVGGSEMMLAGLAMLCAHAMFKAALFMVVGIIDHATGT RDIRRLAWLGDRSKPLLIIGCAAAASMAALPPFFGFIAKEADFETVLHSPYLGAASPFVLAGIVLGSVLT TVYSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAGLVFGLWPKPLDTVLSNYSDTVPDPQ GYDGDYYLALWHGVNLPLILSALVLLAGVAVCVGRGRLRRARLPYVPLGNADRTYDAVIRGADILSVRLT ALTQRGSLPQTQSFILITLVLLPLGVLAFGARDRPEFALWDSPPQVIVGLLMVAAAIAAVVMRNRLAAVL MVGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVAFVLVLRTLPAETSREENTRYRLPRAALALAVGAAV TTLAAYAMAARTGRPIADLLPEAAYVLGHGSNTVNVLLVDIRAWDTMGEISVLLVAATGVASMVFRSRRF GAAPRVSDAGQPDIGLLPSSYNISPAAGEITWLRGSELRDPRHRSLVLEVATRLIFPVMMVLSAYFFFAG HNVPGGGFAGGLMAGLALVLRYLAGGRYELGETLPLDAGKILGAGLALSAGTAVASLLLGAPALSSAVIE FDVPVLGSVKFVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQRRQTDRTVRQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0162 | - | - | 100% (968) | putative monovalent cation/H+ antiporter subunit A |
| M. gilvum PYR-GCK | Mflv_4492 | - | 3e-46 | 30.69% (492) | NADH dehydrogenase subunit L |
| M. gilvum PYR-GCK | Mflv_0164 | - | 5e-32 | 29.30% (372) | putative monovalent cation/H+ antiporter subunit D |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3180 | nuoL | 3e-46 | 30.19% (477) | NADH dehydrogenase subunit L |
| M. tuberculosis H37Rv | Rv3156 | nuoL | 2e-46 | 30.19% (477) | NADH dehydrogenase subunit L |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0636c | - | 0.0 | 71.04% (960) | putative monovalent cation/H+ antiporter subunit A |
| M. marinum M | MMAR_1472 | nuoL | 5e-46 | 32.13% (417) | NADH dehydrogenase I (chain L) NuoL (NADH- ubiquinone |
| M. avium 104 | MAV_4044 | - | 1e-49 | 32.01% (478) | NADH dehydrogenase subunit L |
| M. smegmatis MC2 155 | MSMEG_0848 | - | 0.0 | 78.79% (957) | putative monovalent cation/H+ antiporter subunit A |
| M. thermoresistible (build 8) | TH_4098 | - | 0.0 | 75.94% (956) | PUTATIVE NADH dehydrogenase (quinone) |
| M. ulcerans Agy99 | MUL_2470 | nuoL | 3e-46 | 32.37% (417) | NADH dehydrogenase subunit L |
| M. vanbaalenii PYR-1 | Mvan_0744 | - | 0.0 | 91.64% (969) | putative monovalent cation/H+ antiporter subunit A |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3180|M.bovis_AF2122/97 MTTSLG-------THYTWLLVALPLAGAAILLFGGRRTDAWGHLLGCAAA
Rv3156|M.tuberculosis_H37Rv MTTSLG-------THYTWLLVALPLAGAAILLFGGRRTDAWGHLLGCAAA
MMAR_1472|M.marinum_M MTNFLG-------TQHTWLLVALPLAGAAILLFGGRRTDAWGHWLGCAAA
MUL_2470|M.ulcerans_Agy99 MTNFLG-------TQHTWLLVALPLAGAAILLFGGRRTDAWGHWLGCAAA
MAV_4044|M.avium_104 MTRTYSKAEHANMTHYTPLLVALPLAGAAILLFGGRRTDRWGHWLGCATA
Mflv_0162|M.gilvum_PYR-GCK -------------------MLAILAAHAAAALLAPLLVYRWGRLAFYPLA
Mvan_0744|M.vanbaalenii_PYR-1 -------------------MLAILAAHAVATLLAPLLVYRWGRMAFYPLA
MSMEG_0848|M.smegmatis_MC2_155 -------------------MLAVLLAHAVATALAPLMVARWGRMAFFPLS
TH_4098|M.thermoresistible__bu -------------------MLAILIAHAIATALAPLLVYRWDRKAFYPLA
MAB_0636c|M.abscessus_ATCC_199 -------------------MLAILLAHALAAAVAPLLVARMGRLAFYPLA
::*: * * .. . .: . :
Mb3180|M.bovis_AF2122/97 LAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGGLQVDFGLQIDQLSM
Rv3156|M.tuberculosis_H37Rv LAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGGLQVDFGLQIDQLSM
MMAR_1472|M.marinum_M LASFGVGATMLADLVGRSADDRLIHQTVFTWMPVSQLQVDFGLQIDQLSI
MUL_2470|M.ulcerans_Agy99 LASFGVGATMLADLVGRSADDRLIHQTVFTWMPVSQLQVDFGLQIDQLSI
MAV_4044|M.avium_104 VAAFVVGVGLLDELLGRPADQRAIHERVFSWIPVGQLQVDLGLQIDQLSV
Mflv_0162|M.gilvum_PYR-GCK LVPLGSLVWVVLNWPAKG----QSRNVDVPWVP--GLSMDITLRFDALAA
Mvan_0744|M.vanbaalenii_PYR-1 LVPLGSLFWVVLNWPAKG----QSHTVDVSWVP--ELSMDITLRFDALAA
MSMEG_0848|M.smegmatis_MC2_155 LVPLGSLVWVALNWPSPD----NIPTVHVSWVP--ELWMDFTLRFDALAA
TH_4098|M.thermoresistible__bu LVPLGSLVWVALNWPRDG----HVPTTDIEWVP--ELAMDVNLRFDSLAA
MAB_0636c|M.abscessus_ATCC_199 LVPFGSLIWVLARWPGNS----PGVRVDIPWVP--ELAMDIALRFDALAA
:..: : . *:* * :*. *::* *:
Mb3180|M.bovis_AF2122/97 CFVLLISGVGSLIHIYSVGYMAEDPDRRR-----FFGYLNLFLASMLLLV
Rv3156|M.tuberculosis_H37Rv CFVLLISGVGSLIHIYSVGYMAEDPDRRR-----FFGYLNLFLASMLLLV
MMAR_1472|M.marinum_M CFVLLITGVGSLIHIYSVAYMAEDPDRRR-----FFGYLNLFLASMLLLV
MUL_2470|M.ulcerans_Agy99 CFVLLITGVGSLIHIYSVAYMAEDPDRRR-----FFGYLNLFLASMLLLV
MAV_4044|M.avium_104 CFVLLITGVGSLIHIYSVAYMAEDADRRR-----FFGYLNLFLASMLLLV
Mflv_0162|M.gilvum_PYR-GCK IMSVLVLAIGALVLFYCADYFRHHDGRIEKRLPSFAAELVAFSGAMFGLV
Mvan_0744|M.vanbaalenii_PYR-1 VMSVLVLAIGALVLFYCADYFHHHDGHKEKRLPSFAAELVAFSGAMFGLV
MSMEG_0848|M.smegmatis_MC2_155 IMSVLVLAIGALVLFYCAHYFHHHDGRMEKRLPSFAAELVAFSGAMFGLV
TH_4098|M.thermoresistible__bu VMSVLVLAIGALVLFYCGDYFHHHDGRREKRLPSFAAELVAFSGAMFGLV
MAB_0636c|M.abscessus_ATCC_199 IMSVLVLGIGSLVLFYCASYFRHRDGHTEPRLPSFAAELVAFSGAMFGLV
: :*: .:*:*: :*. *: . .: . * . * * .:*: **
Mb3180|M.bovis_AF2122/97 VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL
Rv3156|M.tuberculosis_H37Rv VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL
MMAR_1472|M.marinum_M VADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGL
MUL_2470|M.ulcerans_Agy99 VADNYVLLYVGWEGVGLASYLLIGFWYHKASAATAAKKAFVMNRVGDAGL
MAV_4044|M.avium_104 IADNYVVLYVGWEGVGLASYLLIGFWYHKPTAATAAKKAFVMNRVGDAGL
Mflv_0162|M.gilvum_PYR-GCK TSDNMLVLYVFWEITTVLSFLLVGHYAERATTRRAAMQALLVTTFGGLAM
Mvan_0744|M.vanbaalenii_PYR-1 TSDNMLVLYVFWEITTVLSFLLVGHYAERATSRRSAMQALLVTTFGGLAM
MSMEG_0848|M.smegmatis_MC2_155 VSDNMLVLYIFWETTTVLSFLLVGHYAERATSRRAATQALLVTTFGGLAM
TH_4098|M.thermoresistible__bu VSDNMLVLYVFWEITTVLSFLLVGHYAERATSRRAATQALLVTTFGGLAM
MAB_0636c|M.abscessus_ATCC_199 ISDNLLVLYIFWELTTVLSFLLVGHYAERLASRRAAVQALLVTTAGGLAM
:** ::**: ** . : *:**:*.: .: :: :* :*:::. *. .:
Mb3180|M.bovis_AF2122/97 AVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACAKSAQVP
Rv3156|M.tuberculosis_H37Rv AVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACAKSAQVP
MMAR_1472|M.marinum_M ALGMFVMFSTFGTLSYAGVFAGAPAASRGALTAMGLLLLLGACAKSAQVP
MUL_2470|M.ulcerans_Agy99 ALGMFVMFSTFGTLSYAGVFAGAPAASRGALTAMGLLLLLGACAKSAQVP
MAV_4044|M.avium_104 ALGMFLMFSTFGTLSYAGVFAGAPAAGRGALTAMGLLLLLGACAKSAQVP
Mflv_0162|M.gilvum_PYR-GCK LVGIVVIGNIADTFLLSELIANPPTG--VAASVALVLILVGALSKSAIVP
Mvan_0744|M.vanbaalenii_PYR-1 LVGIVVIGNIAGTFLLSELIADPPTG--LAASVAVVLILVGALSKSAIVP
MSMEG_0848|M.smegmatis_MC2_155 LTGIVVLGNMAGTYLLSELIAAPPTG--TAASVGIALILIGALSKSAIVP
TH_4098|M.thermoresistible__bu LAGIVVLGNLAGTYLLSELIAAPPTG--VAATVAVVLVLVGALSKSAIVP
MAB_0636c|M.abscessus_ATCC_199 LVGVIVLGHVGGSFLLSDLIANPPTG--LAASVGLVLVLIGALSKSAIVP
*:.: .: : ::* *:. . :. *:*:** :*** **
Mb3180|M.bovis_AF2122/97 LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPTAQLAVV
Rv3156|M.tuberculosis_H37Rv LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPTAQLAVV
MMAR_1472|M.marinum_M LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNPLYNLAPDAQLAVV
MUL_2470|M.ulcerans_Agy99 LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNLLYNLAPDAQLAVV
MAV_4044|M.avium_104 LQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSNPLYNLSPDAQLAVV
Mflv_0162|M.gilvum_PYR-GCK LHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPEWRPTVV
Mvan_0744|M.vanbaalenii_PYR-1 MHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADSPEWRPTVV
MSMEG_0848|M.smegmatis_MC2_155 MHFWLPGAMAAPTPVSAYLHAAAMVKAGVYLIARMTPGFADTAFWRPMVI
TH_4098|M.thermoresistible__bu LHFWLPGAMAAPSPVSAYLHAAAMVKAGVYLVARMTPGFADFSVWRPMAI
MAB_0636c|M.abscessus_ATCC_199 LHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLLARMSPGFAEAAPWRPVVL
:: ** .** .*:**** :***:**.**:**:.* : . : .:
Mb3180|M.bovis_AF2122/97 IVGAVTLLYGAIIGCAKDDIKRALAASTISQIGYMVLAAGLGPAGYAFA-
Rv3156|M.tuberculosis_H37Rv IVGAVTLLFGAIIGCAKDDIKRALAASTISQIGYMVLAAGLGPAGYAFA-
MMAR_1472|M.marinum_M VVGTVTLLLGAVIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA-
MUL_2470|M.ulcerans_Agy99 VVGTVTLLLGGVIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA-
MAV_4044|M.avium_104 IVGAVTLLLGAFIGCAKDDIKRALAASTMSQIGYMVLAAGLGPAGYAFA-
Mflv_0162|M.gilvum_PYR-GCK GLGLLTMLLAGWRAIREYDLKLILAFGTVSQLGFITIMVGVGGSEMMLAG
Mvan_0744|M.vanbaalenii_PYR-1 TLGLLTMLLAGWRAIREYDLKLILAFGTVSQLGFITVMVGVGGSEMMLAG
MSMEG_0848|M.smegmatis_MC2_155 GLGLLTMLLAGWRAVREYDLKLILAFGTVSQLGLITVMVGAGGPDMMLAG
TH_4098|M.thermoresistible__bu VLGLATLLLAGWRAIREYDLKLILAFGTVSQLGLITVLVSAGSGDLMLAG
MAB_0636c|M.abscessus_ATCC_199 VLGIATMILAGWRALREYDLKLILAFGTVSQLGFLVVLTGTGDPDILLAG
:* *:: .. . : *:* ** .*:**:* :.: .. * :*
Mb3180|M.bovis_AF2122/97 IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFATFGL
Rv3156|M.tuberculosis_H37Rv IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFATFGL
MMAR_1472|M.marinum_M IMHLLTHGFFKAGLFLGSGSVIHAMHEEQDMRRYGGLRAALPVTFVTFGL
MUL_2470|M.ulcerans_Agy99 IMHLLTHGFFKAGLFLGSGSVIHAIHEEQDMRRYGGLRAALPVTFVTFGL
MAV_4044|M.avium_104 IMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFVTFGL
Mflv_0162|M.gilvum_PYR-GCK LAMLCAHAMFKAALFMVVGIIDHATG-TRDIRRLAWLGDRSKPLLIIGCA
Mvan_0744|M.vanbaalenii_PYR-1 LAMLCAHAMFKAALFMTVGIIDHATG-TRDIRRLAWLGDRSRPLLIVGCA
MSMEG_0848|M.smegmatis_MC2_155 LAMLIAHAMFKASLFMVVGVIDHATG-TRDIRRLAGLGRAHRPLLIIALG
TH_4098|M.thermoresistible__bu LAMLVAHAMFKAALFMVVGIIDHTTG-TRDIRRLAWLGNRNKPLLVIAVA
MAB_0636c|M.abscessus_ATCC_199 LVMLCAHALFKAALFMVVGIIDHTVG-TRDIRKLAWLGNRQPPLLVIAGI
: * :*.:***.**: * : *: :*:*: . * :
Mb3180|M.bovis_AF2122/97 AYLAIIGVPPFAGFFSKDAIIEAALGAG--GIRGSLLGGAALLGAGVTAF
Rv3156|M.tuberculosis_H37Rv AYLAIIGVPPFAGFFSKDAIIEAALGAG--GIRGSLLGGAALLGAGVTAF
MMAR_1472|M.marinum_M GYLAIIGVPPFAGFFSKDAIIEAALGAG--DTRGYVLGGAALLGAGVTAF
MUL_2470|M.ulcerans_Agy99 GYLAIIGVPPFAGFFSKDAIIEAALGAG--DTRGYVLGGAALLGAGVTAF
MAV_4044|M.avium_104 GYLAIIGVPPFAGFFSKDAIIEAALAAG--GVRGYLLGGAALLGAGVTAF
Mflv_0162|M.gilvum_PYR-GCK AAASMAALPPFFGFIAKEADFETVLHSPYLGAASPFVLAGIVLGSVLTTV
Mvan_0744|M.vanbaalenii_PYR-1 AAASMAALPPFFGFVAKEADFETVLHSPYLGAASPFVLAGIVLGSVLTTV
MSMEG_0848|M.smegmatis_MC2_155 AVASMAALPPFFGFVAKEADLETVLHSPALGTAAPYVLTGIVVGSVFTTI
TH_4098|M.thermoresistible__bu AAASMGAIPPFFGFVAKEAVFETMLHSEQLGPSGPWVLAGLVLGSVFTTI
MAB_0636c|M.abscessus_ATCC_199 AAASMAGVPLTLGFVGKELAFATVLHSRVLGSAAPWVLAGIVIGSMFTIT
. :: .:* **..*: : : * : . . : . ::*: .*
Mb3180|M.bovis_AF2122/97 YMTRVMLMTFFG--------------------------------------
Rv3156|M.tuberculosis_H37Rv YMTRVMLMTFFG--------------------------------------
MMAR_1472|M.marinum_M YMTRVMLMTFFG--------------------------------------
MUL_2470|M.ulcerans_Agy99 YMTRVMLMTFFG--------------------------------------
MAV_4044|M.avium_104 YMTRVMLMTFFG--------------------------------------
Mflv_0162|M.gilvum_PYR-GCK YSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAGLVFGLWP
Mvan_0744|M.vanbaalenii_PYR-1 YSLRFVFGAFGRKGLPHPSTRVEEMHRPELGFLIPPAILAAAGLLFGLWP
MSMEG_0848|M.smegmatis_MC2_155 YSLRFLWGAFAGKGLSGPSVRVAEMHRPPVNFLLAPAILSAAGLVFGLWP
TH_4098|M.thermoresistible__bu YSLRFVVGAFGRKGLPGPSRRVEEQHRTPVTFLLAPGVLAAAALVFGVWP
MAB_0636c|M.abscessus_ATCC_199 YSMRFMWGAFARKGLPEPSARVQGMHTPTPAFLTAPALLAVTSVAVGILP
* *.: :*
Mb3180|M.bovis_AF2122/97 --------------------------------------------------
Rv3156|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1472|M.marinum_M --------------------------------------------------
MUL_2470|M.ulcerans_Agy99 --------------------------------------------------
MAV_4044|M.avium_104 --------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK KPLDTVLSNYSDTVPDPQGYDGDYYLALWHGVNLPLILSALVLLAGVAVC
Mvan_0744|M.vanbaalenii_PYR-1 KPLDTVLRNYSDTVPDPLGYTGDYHLALWHGVNLPLLLSVLVLAAGIGVY
MSMEG_0848|M.smegmatis_MC2_155 KGLDAVLEDYADTVPG----GSTYHLALWHGVGLPLLLSIVVLATGFTVF
TH_4098|M.thermoresistible__bu SPVDAALHSYAETVPNG-VLLGHYQLALWHGFGPPLLLSAVVIGLGVTVY
MAB_0636c|M.abscessus_ATCC_199 GWLNGTLGSYADPVDA--------HIAIWEGFGIPLLLTAIAFAVGILAF
Mb3180|M.bovis_AF2122/97 ------------------------------------------EKRWTPGA
Rv3156|M.tuberculosis_H37Rv ------------------------------------------EKRWTPGA
MMAR_1472|M.marinum_M ------------------------------------------EKRWAPGA
MUL_2470|M.ulcerans_Agy99 ------------------------------------------EKRWAPGA
MAV_4044|M.avium_104 ------------------------------------------EKRWAPGS
Mflv_0162|M.gilvum_PYR-GCK VGRGRLR-RARLPYVPLGNADRTYDAVIRGADILSVRLTALTQRGSLPQT
Mvan_0744|M.vanbaalenii_PYR-1 FGRKRLR-RARADFVPLGNADRIYDAVIRGADVLSVRLTALTQRGSLPQT
MSMEG_0848|M.smegmatis_MC2_155 LVRHRLP-KAKSGFLPLGNADRIYDAVIRGLDVVSLRLTASTQRGSLPAT
TH_4098|M.thermoresistible__bu FLREVLRRRARLPMEVLGNADIVYDKVMRGLDLLAVRTTAITQRGSIPAT
MAB_0636c|M.abscessus_ATCC_199 FSRGRLR-RARLAVNPLGNADRGYDAVLRGADVLSQRLTALTQRGSIPFT
:: * :
Mb3180|M.bovis_AF2122/97 HPHEAPAVMTWPMILLAVGSVFSGGLLAVGGTLRHWLQPVVGSHEEATHA
Rv3156|M.tuberculosis_H37Rv HPHEAPAVMTWPMILLAVGSVFSGGLLAVGGTLRHWLQPVVGSHEEATHA
MMAR_1472|M.marinum_M HPHEAPALMTWPMILLAFGSVFSGGLLAMGGTLQRWLEPVVGAHEEATHA
MUL_2470|M.ulcerans_Agy99 HPHEAPALMTWPMILLAFGSVFSGGLLAMGGTLQRWLEPVGGAHEEATHA
MAV_4044|M.avium_104 HPHEAPGLMTWPMILLAVGSVFSGGLFAVGGTLQRWLEPVVGRHEEVTHA
Mflv_0162|M.gilvum_PYR-GCK QSFILITLVLLPLGVLAFGARDRPEFALWDSPPQVIVGLLMVAAAIAAVV
Mvan_0744|M.vanbaalenii_PYR-1 QSFILVTLVLLPLGVLALGARDRPRFELWDSPPQVVVGLLMVAAALAAVV
MSMEG_0848|M.smegmatis_MC2_155 QSVILLTLVLFPTAALVLGAHNRPDLQLWDSPLQVVVGLLMLAAALGATV
TH_4098|M.thermoresistible__bu QSVILSVLVLVPVVVLAVGARDRPGFELWDTPLHTVVAAAALAAAAGTTV
MAB_0636c|M.abscessus_ATCC_199 QATILVTLVMLPTIVLAVGDRDQAHLKLWDSPLQGVVGLLILAAAIGATV
:. :: * *..* : . . : : : .
Mb3180|M.bovis_AF2122/97 LPTWVATTLALGVVAVGIAVAYRMYGTAPIPR------------------
Rv3156|M.tuberculosis_H37Rv LPTWVATTLALGVVAVGIAVAYRMYGTAPIPR------------------
MMAR_1472|M.marinum_M LPTWVSTTVALGVVAVGIAVAYRMYGTAAIPR------------------
MUL_2470|M.ulcerans_Agy99 LPTWVSTTVALGVVAVGIVVAYRMYGTAAIPR------------------
MAV_4044|M.avium_104 VPVWISTALALGVVAVGIAVAYRLYATAPIPR------------------
Mflv_0162|M.gilvum_PYR-GCK MRNRLAAVLMVGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVAFVLVLR
Mvan_0744|M.vanbaalenii_PYR-1 MRNRLAAVLLVGVTGYGCGAIFAFHGAPDLALTQFLVETLTLVAFVLVLR
MSMEG_0848|M.smegmatis_MC2_155 MRNRLAAVLLVGVTGYGCGAIFAFHGAPDLALTQFLVETLVLVIFVLVLR
TH_4098|M.thermoresistible__bu MRNRLAAALLVGVTGYSCGAIFAFHGAPDLALTQFLVETVTLVIFVLVLR
MAB_0636c|M.abscessus_ATCC_199 MRNRLAAVLLVGITGYGTGTIFALHGAPDLALTQFLVETLTLVIFVLVLR
: :::.: :*:.. . . : ::.:. :.
Mb3180|M.bovis_AF2122/97 --------------------------VAPVRVSALTAAAR-ADLYGDAFN
Rv3156|M.tuberculosis_H37Rv --------------------------VAPVRVSALTAAAR-ADLYGDAFN
MMAR_1472|M.marinum_M --------------------------VAPVRVSVLTTAAR-ADMYADAFN
MUL_2470|M.ulcerans_Agy99 --------------------------VAPVRVSVLTTAAR-ADMYADAFN
MAV_4044|M.avium_104 --------------------------VAPLSVSPLTTAVR-NDFYGDAFN
Mflv_0162|M.gilvum_PYR-GCK TLPAETSREENTRYRLPRAALALAVGAAVTTLAAYAMAARTGRPIADLLP
Mvan_0744|M.vanbaalenii_PYR-1 TLPAETSRAENTRFRVPRAALAVAVGATVTTLAAFAMAARTGRPIAELLP
MSMEG_0848|M.smegmatis_MC2_155 TLPAEADAANINKNRLPRALLALSVGAAVTTLTVYAMAARTGPGVAVLLP
TH_4098|M.thermoresistible__bu SLPPETDQAQISRFRWPRAVLALSVGFSLTTLAVFALAARDGMAVAALLP
MAB_0636c|M.abscessus_ATCC_199 ALPAESDIQQANRFRLPRAVLAIAVGCTVTALGVYAMAARRDRPIADLLP
: : : *.* . :
Mb3180|M.bovis_AF2122/97 EEVFMRPGAQLTNAVVAVDDAGVDGSVNALATLVSQTSNR----------
Rv3156|M.tuberculosis_H37Rv EEVFMRPGAQLTNAVVAVDDAGVDGSVNALATLVSQTSNR----------
MMAR_1472|M.marinum_M EEVFMRPGAQLTDAVVEVDNAGVDGSVNALAGLVSMTSNR----------
MUL_2470|M.ulcerans_Agy99 EEVFMRPGAQLTDAVVEVDNAGVDGSVNALAGLVSMTSNR----------
MAV_4044|M.avium_104 EEVFMRPGAQLTHALVEVDDAGVDGSVNALAALVSATSNR----------
Mflv_0162|M.gilvum_PYR-GCK EAAYVLGHGSNTVNVLLVDIRAWDTMGEISVLLVAATGVASMVFRSRRFG
Mvan_0744|M.vanbaalenii_PYR-1 EAAYVLGHGSNTVNVILVDIRAWDTMGEVSVLLVAATGVASMVFRSRRFG
MSMEG_0848|M.smegmatis_MC2_155 DAAYYRGHGSNTVNVLLVDIRAWDTMGEVMVLLVAATGVASLVFRHRRFG
TH_4098|M.thermoresistible__bu DAAYHLGHGANTVNVILVDIRAWDTMGEIMVLVVAATGVASMVFRHRRFG
MAB_0636c|M.abscessus_ATCC_199 QAAYQRGHGANTVNVLLVDIRAWDTLGEISVLLVAATGVASLMFRHRRFG
: .: . * :: ** . * : . :*: *.
Mb3180|M.bovis_AF2122/97 --------------------------------LRQMQTGFARNYALSMLV
Rv3156|M.tuberculosis_H37Rv --------------------------------LRQMQTGFARNYALSMLV
MMAR_1472|M.marinum_M --------------------------------LRRMQTGFARNYALSMLA
MUL_2470|M.ulcerans_Agy99 --------------------------------LRLMQTGFARNYALSMLA
MAV_4044|M.avium_104 --------------------------------LRGLQTGFARNYALSMLT
Mflv_0162|M.gilvum_PYR-GCK AAPRVS-DAGQPDIGLLPSSYNISPAAGEITWLRGSELRDPRHRSLVLEV
Mvan_0744|M.vanbaalenii_PYR-1 AAPRVS-DAGQPDIGRLPTSFNTSPAAGDIIWLRGSGLRDPRHRSLVLEV
MSMEG_0848|M.smegmatis_MC2_155 AAPRVSTAVGQPDIGPVAA---YSPAAGDVTWLRGSELRDPRHRSLILEV
TH_4098|M.thermoresistible__bu SPPRVS-DAGQPDIGRIAQFVDISPAVGDITWLRGSEFRDPQHRSLVLEV
MAB_0636c|M.abscessus_ATCC_199 RAPRVGDAAGQPDV-----------VVASGIWLRGSELRDPKHRSLVLEV
** .:: :* : .
Mb3180|M.bovis_AF2122/97 GAVLVAAALLVVQLW-----------------------------------
Rv3156|M.tuberculosis_H37Rv GAVLVAAALLVVQLW-----------------------------------
MMAR_1472|M.marinum_M GAVLVAAVLLAVQLW-----------------------------------
MUL_2470|M.ulcerans_Agy99 GAVLVAAVLLAVQLW-----------------------------------
MAV_4044|M.avium_104 GAVLVIALILAVRLW-----------------------------------
Mflv_0162|M.gilvum_PYR-GCK ATRLIFPVMMVLSAYFFFAGHNVPGGGFAGGLMAGLALVLRYLAGGRYEL
Mvan_0744|M.vanbaalenii_PYR-1 ATRLIFPVMMVLSAYFFFAGHNVPGGGFAGGLMAGLALVLRYLAGGRYEL
MSMEG_0848|M.smegmatis_MC2_155 ATRLIFPLIMVLSAYFFFAGHNTPGGGFAGGLVAGLALVLRYLAGGRYEL
TH_4098|M.thermoresistible__bu ATRIIFPLMMVLSAYFFFAGHNSPGGGFAGGLTAGLAVVLRYIAGGRYEL
MAB_0636c|M.abscessus_ATCC_199 ATRLIFPLVMVLSFYFFFAGHNVPGGGFAGGLTAGLALVLRYLAGGRYEL
.: :: . ::.: :
Mb3180|M.bovis_AF2122/97 --------------------------------------------------
Rv3156|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1472|M.marinum_M --------------------------------------------------
MUL_2470|M.ulcerans_Agy99 --------------------------------------------------
MAV_4044|M.avium_104 --------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK GETLPLDAGKILGAGLALSAGTAVASLLLGAPALSSAVIEFDVPVLGSVK
Mvan_0744|M.vanbaalenii_PYR-1 GETLPLDAGKILGAGLTLAAGTAAASLFLGAPVLSSALIQVDLPVLGTVK
MSMEG_0848|M.smegmatis_MC2_155 GETLPLDAGKILGTGLGLSAGTAVASLLLGAPALSSAVVQLDVPVIGPIK
TH_4098|M.thermoresistible__bu GETIPLDAGKVLGAGLTLAAGTAATSLLLGAPALSSALIELTLPVLGQVT
MAB_0636c|M.abscessus_ATCC_199 GETLPFDAGKILGLGLAFSGGAALSSMLLGAPVLSSATIQFDMLGFGHVK
Mb3180|M.bovis_AF2122/97 -------------------------------------------------
Rv3156|M.tuberculosis_H37Rv -------------------------------------------------
MMAR_1472|M.marinum_M -------------------------------------------------
MUL_2470|M.ulcerans_Agy99 -------------------------------------------------
MAV_4044|M.avium_104 -------------------------------------------------
Mflv_0162|M.gilvum_PYR-GCK FVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQRR-QTDRTVRQR
Mvan_0744|M.vanbaalenii_PYR-1 FVTALFFDLGVYLIVVGLVLDVLRSLGARIDVELSEQSRPQTGRMARQR
MSMEG_0848|M.smegmatis_MC2_155 FVTALFFDLGVYLIVVGLVLDVLRSLGARVDVELAESGQPQKAAA----
TH_4098|M.thermoresistible__bu FMTTLFFDLGVYLIVVGLVLDVLRSLGARLDVELAGPAPARAVAKPR--
MAB_0636c|M.abscessus_ATCC_199 IVTAIFFDLGVYLVVVGLVLDVLRSLGARLDVELEESPRTRAGARTS--