For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3911 (-)

annotation: putative short-chain dehydrogenase/reductase SDR
coordinates: 804062 - 804838
length: 259

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3911--100% (259)putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3477-8e-4136.61% (254) PUTATIVE putative 3-oxoacyl-(acyl-carrier-protein) reductase,
M. thermoresistible (build 8)TH_3102-9e-3235.20% (250) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1519fabG19e-2430.00% (250) 3-oxoacyl-
M. gilvum PYR-GCKMflv_2501-5e-3437.15% (253) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1483fabG19e-2430.00% (250) 3-oxoacyl-
M. leprae Br4923MLBr_01807fabG11e-2432.80% (250) 3-oxoacyl-
M. abscessus ATCC 19977MAB_2723c-7e-2731.08% (251) 3-oxoacyl-
M. marinum MMMAR_4715-2e-3236.11% (252) 3-oxoacyl-
M. avium 104MAV_0942-2e-2935.20% (250) 3-oxoacyl-(acyl-carrier-protein) reductase, putative
M. smegmatis MC2 155MSMEG_6538-3e-3336.80% (250) 3-oxoacyl-(acyl-carrier-protein) reductase, putative
M. ulcerans Agy99MUL_0315fabG22e-3136.00% (250) 3-oxoacyl-
M. vanbaalenii PYR-1Mvan_4157-3e-3740.08% (252) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2501|M.gilvum_PYR-GCK          MK--------------------NAVVTGGASGIGAAVVERLRADGLQVAT
Mvan_4157|M.vanbaalenii_PYR-1       MK--------------------NAVVTGGASGIGAAIAERLRADGMRVAT
MMAR_4715|M.marinum_M               MK--------------------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99           MRPDSSPS----------WCTITSVVTGGASGIGLAIARRLSADGTDVAT
MAV_0942|M.avium_104                MK--------------------TAVVTGGGSGIGLAVVERLRADGLNVAS
MSMEG_6538|M.smegmatis_MC2_155      MT------------------AKTALVTGGASGIGKAIAERLASDGHQVAI
TH_3911|M.thermoresistible__bu      MTK-----------------PRNALVTGGTDGIGKAIALRLRADGMRVAV
Mb1519|M.bovis_AF2122/97            MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
Rv1483|M.tuberculosis_H37Rv         MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_2723c|M.abscessus_ATCC_199      MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAV
                                    *                     . :****  *** *:. ** :**  ** 

Mflv_2501|M.gilvum_PYR-GCK          IDLNPGD-----------AKFSYA-ADVTDRSAVDAALDEIRAELGPVTV
Mvan_4157|M.vanbaalenii_PYR-1       IDLNPGD-----------EKFSYA-ADVTDRAAVDAVLSEIHTELGPVTV
MMAR_4715|M.marinum_M               LDLKTPD-----------GELAFS-ADVTNRSQVDAALTAIRQRLGPVTI
MUL_0315|M.ulcerans_Agy99           LDLKTPD-----------GGLAFS-ADVTNRSQVDAALAAIRQRLGPVTI
MAV_0942|M.avium_104                IDLRPSD-----------AELAFT-ADVTDRSQVDAALSAIRAQLGPVTV
MSMEG_6538|M.smegmatis_MC2_155      LDLNPGD-----------GPHAYT-ADVTDRAQVDGVFKAVREELGPVSI
TH_3911|M.thermoresistible__bu      TGRNAERGAQLVDEVGCPEEFVFIRSDATDPHDAERVAAEVRNALGGIGV
Mb1519|M.bovis_AF2122/97            THRGSGAP----------KGLFGVECDVTDSDAVDRAFTAVEEHQGPVEV
Rv1483|M.tuberculosis_H37Rv         THRGSGAP----------KGLFGVECDVTDSDAVDRAFTAVEEHQGPVEV
MLBr_01807|M.leprae_Br4923          THRASVVP----------DWFFGVECDVTDNDAIGAAFKAVEEHQGPVEV
MAB_2723c|M.abscessus_ATCC_199      THRGSGAP----------EGLLGVQCDITDNDQIDAAFKEVEEKQGPVEV
                                        .                    .* *:      .   :.   * : :

Mflv_2501|M.gilvum_PYR-GCK          LVNAAG---LDRFKKFLDLSFEEWQKVVDVNLNGVFHCTQAVLPDMIEAG
Mvan_4157|M.vanbaalenii_PYR-1       LVNAAG---LDRFKKFLDLTFDEWQKVVDVNLNGVFHCTQAVLPDMIEAG
MMAR_4715|M.marinum_M               LVNAAG---LDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
MUL_0315|M.ulcerans_Agy99           LVNAAG---LDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
MAV_0942|M.avium_104                LVNAAG---LDGFKKFNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEAG
MSMEG_6538|M.smegmatis_MC2_155      LVNAAG---LSDFTPFTDISFDHWQRVVNVNLHGVFHVVQAALPDMVAAG
TH_3911|M.thermoresistible__bu      LVNNVGGGSSNEFGYIHDLDPDAWLDSFNRNVMSAIRMTRAVVPDMLAAS
Mb1519|M.bovis_AF2122/97            LVSNAG---LSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNK
Rv1483|M.tuberculosis_H37Rv         LVSNAG---LSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNK
MLBr_01807|M.leprae_Br4923          LVANAG---ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
MAB_2723c|M.abscessus_ATCC_199      LVANAG---ITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKR
                                    **  .*         :  :  : :   .: *: ..::  : .  .*    

Mflv_2501|M.gilvum_PYR-GCK          WGRIVNISSSS-THSGQPYMSPYVAAKSAVNGLTKSLALEYGPAGITVNA
Mvan_4157|M.vanbaalenii_PYR-1       WGRIVNISSSS-THSGQPYMSPYVAAKSAVNGLTKSLALEYGPDGITVNA
MMAR_4715|M.marinum_M               WGRIVNISSSS-THSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNA
MUL_0315|M.ulcerans_Agy99           WGRIVNISSSS-THSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNA
MAV_0942|M.avium_104                WGRIVNISSSS-THSGAPYMSHYVAAKSAVNGLTKSLALEYGPKGITVNA
MSMEG_6538|M.smegmatis_MC2_155      WGRIVNISSSS-THSGVPYMSSYVSAKSAVNGLTKSLALEFGPAGITVNA
TH_3911|M.thermoresistible__bu      WGRIVMMSSLEGKMPTLPKIGPYVTSKHALLGLTKSLAFDYGAHGITCNA
Mb1519|M.bovis_AF2122/97            FGRMIFIGSVS-GSWGIGNQANYAASKAGVIGMARSIARELSKANVTANV
Rv1483|M.tuberculosis_H37Rv         FGRMIFIGSVS-GSWGIGNQANYAASKAGVIGMARSIARELSKANVTANV
MLBr_01807|M.leprae_Br4923          FGRYIFMGSVV-GLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
MAB_2723c|M.abscessus_ATCC_199      FGRLIFMGSVA-GQIGLPGQANYSASKAGLVGMARALTRELGSRSITANV
                                    :** : :.*             * ::* .: *:::::: : .  .:* *.

Mflv_2501|M.gilvum_PYR-GCK          VPPGFIDTPMLR----KAEQRGFLGDTEQQIQQTP-VRRMGRPEDIAAAC
Mvan_4157|M.vanbaalenii_PYR-1       VPPGFIDTPMLR----KAEQRGFLGDTQKQIEQTP-VRRMGRPEDIAAAC
MMAR_4715|M.marinum_M               VPPGFIDTPMLR----NAAAQGHLGDIEQNIARTP-VRRIGKPEDIAAAC
MUL_0315|M.ulcerans_Agy99           VPPGFIDTPMLR----NAAAQGHLGDIEQNIARTP-VRRIGKPEDIAAAC
MAV_0942|M.avium_104                VPPGFIDTPMLR----AAEKNGFLGDIEETIARTP-VRRMGTPQDIAAAC
MSMEG_6538|M.smegmatis_MC2_155      VPPGFIDTPMLR----AAEARGELGDIDDTIAATP-VRRMGRPEDIAATC
TH_3911|M.thermoresistible__bu      VCPGYVHIPTRQRKASKAFDEGRFADPQQNYKDLSRIGRHIELDEVAHAV
Mb1519|M.bovis_AF2122/97            VAPGYIDTDMTR-----ALDER---IQQGALQFIP-AKRVGTPAEVAGVV
Rv1483|M.tuberculosis_H37Rv         VAPGYIDTDMTR-----ALDER---IQQGALQFIP-AKRVGTPAEVAGVV
MLBr_01807|M.leprae_Br4923          VAPGFIDTEMTR-----AMDSK---YQEAALQAIP-LGRIGAVEEIAGAV
MAB_2723c|M.abscessus_ATCC_199      VAPGFIDTDMTR-----ELGEK---HVETALTAIP-MGRIGEPSEVAGVV
                                    * **::.    :               :      .   *     ::* . 

Mflv_2501|M.gilvum_PYR-GCK          AFFISEEAGYITGQILGVNGGRNT--
Mvan_4157|M.vanbaalenii_PYR-1       SFLISEEAGYITGQILGVNGGRNT--
MMAR_4715|M.marinum_M               AFLVSEEAGYITGQILGVNGGRNT--
MUL_0315|M.ulcerans_Agy99           AFLVSEEAGYITGQILGVNGGRNT--
MAV_0942|M.avium_104                AFLVSEEAGYITGQILGVNGGRNT--
MSMEG_6538|M.smegmatis_MC2_155      SFLISEEAGYITGQIIGVNGGRNT--
TH_3911|M.thermoresistible__bu      SMLVAEESSAITGTTLNIDGGSSPY-
Mb1519|M.bovis_AF2122/97            SFLASEDASYISGAVIPVDGGMGMGH
Rv1483|M.tuberculosis_H37Rv         SFLASEDASYISGAVIPVDGGMGMGH
MLBr_01807|M.leprae_Br4923          SFLASEDAGYISGAVIPVDGGLGMGH
MAB_2723c|M.abscessus_ATCC_199      SWLASPDAAYVSGAVIPVDGGLGMGH
                                    : : : ::. ::*  : ::** .