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M. thermoresistible (build 8) TH_3766 (-)

annotation: Na+/H+ antiporter NhaA
coordinates: 4322266 - 4323591
length: 442

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3766--100% (442)Na+/H+ antiporter NhaA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3924nhaA0.073.41% (440) Na+/H+ antiporter NhaA
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2991c-1e-16367.88% (439) Na+/H+ antiporter NhaA
M. marinum MMMAR_3635-1e-0625.36% (280) integral membrane ion antiporter
M. avium 104-----
M. smegmatis MC2 155MSMEG_2775nhaA1e-14363.17% (429) Na+/H+ antiporter NhaA
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2476nhaA0.074.08% (436) Na+/H+ antiporter NhaA

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3924|M.gilvum_PYR-GCK          ----------------MAATPLPPPR---RPVFSRGSWAETRRVTEILRK
Mvan_2476|M.vanbaalenii_PYR-1       MCREDWSASIRRRPVRQAVTSDPRARRIRRALLARGSWSETNRVTEILRK
TH_3766|M.thermoresistible__bu      ----------------VIARPLRRPP---RRLLTRGSWAETSRITAILRR
MAB_2991c|M.abscessus_ATCC_199      ----------------MRLS---------QRVFTRGSWAESSRVAEILRK
MSMEG_2775|M.smegmatis_MC2_155      ----------------MTDQPETFR----RRIFSRSSWPEWQRVSELLRT
MMAR_3635|M.marinum_M               -------------------------------MLADELLEFFLQFGLLLLA
                                                                   :::        :.  :*  

Mflv_3924|M.gilvum_PYR-GCK          ETVGG---VILLVAAAAALIWANSPWAEGYFALRDLELGGEWFGLHLNLT
Mvan_2476|M.vanbaalenii_PYR-1       ETVGG---IILLVAAAAALIWANSPWSQSYFALRDFELGGEWLGLHLNLT
TH_3766|M.thermoresistible__bu      ETVGG---GVLLVVAAAALLWANSPWSAGYFGLRDATVGGEPLGLHLNLT
MAB_2991c|M.abscessus_ATCC_199      ETVGG---VLLVVAAVAALLWANSPWSSWYYRLGAITVGPE--QLHLHLT
MSMEG_2775|M.smegmatis_MC2_155      ETVGG---ALLLVAALAALVWANSPWSAGYDQVSDFVVGPH--SLHLDLS
MMAR_3635|M.marinum_M               ATILGRVAIRLGMPAIAGELCAGVLLGPSILGQVAPGLSSWLLPEQVSER
                                     *: *     * : * *. : *.   .          :.      ::   

Mflv_3924|M.gilvum_PYR-GCK          LGAWAADGLLAIFFL-VVGLELKREFVAGDLRDPSRAALPIAAAVGGMVV
Mvan_2476|M.vanbaalenii_PYR-1       LGAWAADGLLAIFFL-VVGLELKREFVAGDLRDPSRAALPIAAAVGGMVV
TH_3766|M.thermoresistible__bu      VGTWAADGLLAIFFL-VVGLELKREFVAGDLRDPARAVLPIVAAVGGMVA
MAB_2991c|M.abscessus_ATCC_199      LAGWATDGLLAIFFF-VVGVELKREFVAGDLRDPGRAALPIVAAVGGMLV
MSMEG_2775|M.smegmatis_MC2_155      ISAWAADGLLAIFFF-VVGVELKREFVVGDLRDPAKAALPIAAAVGGMIV
MMAR_3635|M.marinum_M               LGLDAVGTFGVLLLMGLTGMQVDLNLLKSNRLAITKISAACLLVPVVFGL
                                    :.  *.. : .:::: :.*:::. ::: .:     :   .   .   :  

Mflv_3924|M.gilvum_PYR-GCK          PALIFVLVNLNTGD-GALRGWAIPTATDIAFAVAVLAVIGTH--LPSALR
Mvan_2476|M.vanbaalenii_PYR-1       PALIFVLVNLNTGD-GALRGWAIPTATDIAFAVAVLAVISTH--LPSALR
TH_3766|M.thermoresistible__bu      PALIFVVVAAGGGE-GALRGWAIPTATDIAFAVAVLAVLSTH--LPAALR
MAB_2991c|M.abscessus_ATCC_199      PAAIYLAVNASGGG-AAMRGWAIPTATDIAFALAVLAVISTH--LPTALR
MSMEG_2775|M.smegmatis_MC2_155      PAVIFVGVNLVAGHTENLGGWAIPVATDIAFALAVLAVIATH--LPSALR
MMAR_3635|M.marinum_M               GIGFLMPSVLTGGSNRLVFALFLAVALSVSAIAVIVKTLSDLGLMHRDIA
                                       : :      *    : .  :..* .::   .:: .:.    :   : 

Mflv_3924|M.gilvum_PYR-GCK          TFLLTLAVVDDLLAITVIAVFYTEDINGLALALAAVPLALFALCVQR---
Mvan_2476|M.vanbaalenii_PYR-1       TFLLTLAVVDDLLAITVIAVFYTDDIKAWALALAVVPLALFTVCAQR---
TH_3766|M.thermoresistible__bu      TFLLTLAVVDDLLAVTVIAVFYTEEINTTALGLTLVPLAAFTVCVQR---
MAB_2991c|M.abscessus_ATCC_199      TFLLTLAVVDDLLAVIVIAVFYTDELHWGPLGLALVPLGLFALAVQR---
MSMEG_2775|M.smegmatis_MC2_155      IFLLTLAVVDDLLAIIVIAVFYTTQLSFGPLAGALVTIAVFGLAVQR---
MMAR_3635|M.marinum_M               QLILATAVIDNVIAWVLLSVVCAMALAHLSLGTVLLTVFLIISVVAATII
                                     ::*: **:*:::*  :::*. :  :   .*. . :.:  :   .     

Mflv_3924|M.gilvum_PYR-GCK          GVQKWWVLVPLSVATWVLMHESG---VHATVAGVLLGFAVPVRRQATPRG
Mvan_2476|M.vanbaalenii_PYR-1       GVQKWWLLVPLSVATWVLVHESG---VHATVAGVLLGFAVPVHRSATRRG
TH_3766|M.thermoresistible__bu      RIRAWWLLIPLGVATWVLMHESG---VHATVAGVLLGFAVPVRRSAAAGG
MAB_2991c|M.abscessus_ATCC_199      RRREWWLLVPLAVATWALVHASG---VHATVAGVLLGFTVPVLR---RDG
MSMEG_2775|M.smegmatis_MC2_155      GVRTPFLLLPLAVVAWALMHASG---VHATVAGVLLGFTIPVLG------
MMAR_3635|M.marinum_M               GRKIVEVFVNSRQQPAAAEHSAGPRPILAYAVGLVMLAAAATHALKLEPV
                                      :   :::     . .  * :*   : * ..*:::  : ..        

Mflv_3924|M.gilvum_PYR-GCK          RGPAPSQRVGMAEYFEHRVRPVSAGIAIPVFAFFAAGVSIGGLDGFTRAL
Mvan_2476|M.vanbaalenii_PYR-1       QQVDHAERVGMAEYFEHRVRPISAGIAIPVFAFFAAGVSIGGLSGLSRAL
TH_3766|M.thermoresistible__bu      ----PAAGPGMAEHFEHRLRPLSAGLAVPVFAFFAAGVDFGGLSGLGDAL
MAB_2991c|M.abscessus_ATCC_199      ----RTDAHGMAEQFEHRLRPLSAGVAVPVFAFFAAGVTLGGFAGLGQAL
MSMEG_2775|M.smegmatis_MC2_155      -------RHACADRMEHRLRPLSAGFAVPVFAFFAAGVTVGGLSGFASAL
MMAR_3635|M.marinum_M               LG-AFAAGIMLAALPPDRRSGLDSLHPVVNNVLAPLYFATAGLQADLTGL
                                               *    .*   :.:  .:   .: .  .  .*: .   .*

Mflv_3924|M.gilvum_PYR-GCK          SDPITLGIVLGLVLGKPIGIVLTTRVLSAVTRANLDASLRWVDVVGMSML
Mvan_2476|M.vanbaalenii_PYR-1       GDPITLGIVLGLVAGKPIGILVTTRVLSAVTRASLDSSLRWVDVLGMSML
TH_3766|M.thermoresistible__bu      RDPVTLGIIGGLVVGKPVGIWLTTRLLAAFTRARLDATLRWVDVFGVSLL
MAB_2991c|M.abscessus_ATCC_199      LDPVALGVVLGLLVGKPVGVFLTTYLLARFTRASLDDDLSWLDIAGVALL
MSMEG_2775|M.smegmatis_MC2_155      SHPVTYGVIAGLVLGKPIGVFLTTYVLARFTNASLDEDLAWRDVLGLALL
MMAR_3635|M.marinum_M               ADRTTLAAALVVLAAAVASKFLGAYIGAKSSGRSGAEAVALG--AGLNAR
                                     .  : .    :: .   .  : : : :  :       :      *:   

Mflv_3924|M.gilvum_PYR-GCK          AGIGFTVSLLIGDLAY--------GLGSERDEFVKIGVLFGSLLAAGVAA
Mvan_2476|M.vanbaalenii_PYR-1       AGIGFTVSLLIGDLAF--------GMGSERDEFVKIGVLSGSLLAASLAA
TH_3766|M.thermoresistible__bu      AGIGFTVSLLIGDLAY--------GTGSIRDDHVKVGVLLGSVTAAALAA
MAB_2991c|M.abscessus_ATCC_199      AGIGFTVSLLIGELAFGAAESATSGVGAETASHVKVGVLAGSLTSAAVAS
MSMEG_2775|M.smegmatis_MC2_155      AGIGFTVSLLIGELAFE--------NSPIAHDDAKIAVLTGSVLAGLLAA
MMAR_3635|M.marinum_M               G----VIQIIIADTAYD--------LGIFNDSFYTIVLLT-AIATSVMAA
                                    .    .:.::*.: *:          .    .  .: :*  :: :. :*:

Mflv_3924|M.gilvum_PYR-GCK          VVLLTRNRAYRRIYREETVDEDRDGVPDVYQTRQDRT-
Mvan_2476|M.vanbaalenii_PYR-1       IVLLTRNRAYRRIHREETADDDHDGVPDVYQTRQD---
TH_3766|M.thermoresistible__bu      AVLRMRNRYYRILHQQETEDADRDGVPDIYQSPNT---
MAB_2991c|M.abscessus_ATCC_199      VVLRLRNRVYQRIEAKETLDADHDGVPDVFGSAPGDRI
MSMEG_2775|M.smegmatis_MC2_155      VVLLSRNAVYRRIHEAETVDADDDGVPDIYQPRQDQ--
MMAR_3635|M.marinum_M               PILRIAAARIAIDPDDEIR--RQDALPEAH--------
                                     :*             *      *.:*: .