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MTDQPETFRRRIFSRSSWPEWQRVSELLRTETVGGALLLVAALAALVWANSPWSAGYDQVSDFVVGPHSL HLDLSISAWAADGLLAIFFFVVGVELKREFVVGDLRDPAKAALPIAAAVGGMIVPAVIFVGVNLVAGHTE NLGGWAIPVATDIAFALAVLAVIATHLPSALRIFLLTLAVVDDLLAIIVIAVFYTTQLSFGPLAGALVTI AVFGLAVQRGVRTPFLLLPLAVVAWALMHASGVHATVAGVLLGFTIPVLGRHACADRMEHRLRPLSAGFA VPVFAFFAAGVTVGGLSGFASALSHPVTYGVIAGLVLGKPIGVFLTTYVLARFTNASLDEDLAWRDVLGL ALLAGIGFTVSLLIGELAFENSPIAHDDAKIAVLTGSVLAGLLAAVVLLSRNAVYRRIHEAETVDADDDG VPDIYQPRQDQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2775 | nhaA | - | 100% (431) | Na+/H+ antiporter NhaA |
| M. smegmatis MC2 155 | MSMEG_6769 | - | 1e-07 | 25.27% (277) | transporter, monovalent cation:proton antiporter-2 (CPA2) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3924 | nhaA | 1e-149 | 63.70% (438) | Na+/H+ antiporter NhaA |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2991c | - | 1e-154 | 65.58% (430) | Na+/H+ antiporter NhaA |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3766 | - | 1e-144 | 63.17% (429) | PUTATIVE Na+/H+ antiporter NhaA |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2476 | nhaA | 1e-148 | 63.16% (437) | Na+/H+ antiporter NhaA |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3924|M.gilvum_PYR-GCK ----------------MAATPLPPPR---RPVFSRGSWAETRRVTEILRK
Mvan_2476|M.vanbaalenii_PYR-1 MCREDWSASIRRRPVRQAVTSDPRARRIRRALLARGSWSETNRVTEILRK
TH_3766|M.thermoresistible__bu ----------------VIARPLRRPP---RRLLTRGSWAETSRITAILRR
MAB_2991c|M.abscessus_ATCC_199 ----------------MRLS---------QRVFTRGSWAESSRVAEILRK
MSMEG_2775|M.smegmatis_MC2_155 ----------------MTDQPETFR----RRIFSRSSWPEWQRVSELLRT
: :::*.**.* *:: :**
Mflv_3924|M.gilvum_PYR-GCK ETVGGVILLVAAAAALIWANSPWAEGYFALRDLELGGEWFGLHLNLTLGA
Mvan_2476|M.vanbaalenii_PYR-1 ETVGGIILLVAAAAALIWANSPWSQSYFALRDFELGGEWLGLHLNLTLGA
TH_3766|M.thermoresistible__bu ETVGGGVLLVVAAAALLWANSPWSAGYFGLRDATVGGEPLGLHLNLTVGT
MAB_2991c|M.abscessus_ATCC_199 ETVGGVLLVVAAVAALLWANSPWSSWYYRLGAITVGPE--QLHLHLTLAG
MSMEG_2775|M.smegmatis_MC2_155 ETVGGALLLVAALAALVWANSPWSAGYDQVSDFVVGPH--SLHLDLSISA
***** :*:*.* ***:******: * : :* . ***.*::.
Mflv_3924|M.gilvum_PYR-GCK WAADGLLAIFFLVVGLELKREFVAGDLRDPSRAALPIAAAVGGMVVPALI
Mvan_2476|M.vanbaalenii_PYR-1 WAADGLLAIFFLVVGLELKREFVAGDLRDPSRAALPIAAAVGGMVVPALI
TH_3766|M.thermoresistible__bu WAADGLLAIFFLVVGLELKREFVAGDLRDPARAVLPIVAAVGGMVAPALI
MAB_2991c|M.abscessus_ATCC_199 WATDGLLAIFFFVVGVELKREFVAGDLRDPGRAALPIVAAVGGMLVPAAI
MSMEG_2775|M.smegmatis_MC2_155 WAADGLLAIFFFVVGVELKREFVVGDLRDPAKAALPIAAAVGGMIVPAVI
**:********:***:*******.******.:*.***.******:.** *
Mflv_3924|M.gilvum_PYR-GCK FVLVNLNTGD-GALRGWAIPTATDIAFAVAVLAVIGTHLPSALRTFLLTL
Mvan_2476|M.vanbaalenii_PYR-1 FVLVNLNTGD-GALRGWAIPTATDIAFAVAVLAVISTHLPSALRTFLLTL
TH_3766|M.thermoresistible__bu FVVVAAGGGE-GALRGWAIPTATDIAFAVAVLAVLSTHLPAALRTFLLTL
MAB_2991c|M.abscessus_ATCC_199 YLAVNASGGG-AAMRGWAIPTATDIAFALAVLAVISTHLPTALRTFLLTL
MSMEG_2775|M.smegmatis_MC2_155 FVGVNLVAGHTENLGGWAIPVATDIAFALAVLAVIATHLPSALRIFLLTL
:: * * : *****.*******:*****:.****:*** *****
Mflv_3924|M.gilvum_PYR-GCK AVVDDLLAITVIAVFYTEDINGLALALAAVPLALFALCVQRGVQKWWVLV
Mvan_2476|M.vanbaalenii_PYR-1 AVVDDLLAITVIAVFYTDDIKAWALALAVVPLALFTVCAQRGVQKWWLLV
TH_3766|M.thermoresistible__bu AVVDDLLAVTVIAVFYTEEINTTALGLTLVPLAAFTVCVQRRIRAWWLLI
MAB_2991c|M.abscessus_ATCC_199 AVVDDLLAVIVIAVFYTDELHWGPLGLALVPLGLFALAVQRRRREWWLLV
MSMEG_2775|M.smegmatis_MC2_155 AVVDDLLAIIVIAVFYTTQLSFGPLAGALVTIAVFGLAVQRGVRTPFLLL
********: ******* :: .*. : *.:. * :..** : ::*:
Mflv_3924|M.gilvum_PYR-GCK PLSVATWVLMHESGVHATVAGVLLGFAVPVRRQATPRGRGPAPSQRVGMA
Mvan_2476|M.vanbaalenii_PYR-1 PLSVATWVLVHESGVHATVAGVLLGFAVPVHRSATRRGQQVDHAERVGMA
TH_3766|M.thermoresistible__bu PLGVATWVLMHESGVHATVAGVLLGFAVPVRRSAAAGG----PAAGPGMA
MAB_2991c|M.abscessus_ATCC_199 PLAVATWALVHASGVHATVAGVLLGFTVPVLR---RDG----RTDAHGMA
MSMEG_2775|M.smegmatis_MC2_155 PLAVVAWALMHASGVHATVAGVLLGFTIPVLG-------------RHACA
**.*.:*.*:* **************::** . *
Mflv_3924|M.gilvum_PYR-GCK EYFEHRVRPVSAGIAIPVFAFFAAGVSIGGLDGFTRALSDPITLGIVLGL
Mvan_2476|M.vanbaalenii_PYR-1 EYFEHRVRPISAGIAIPVFAFFAAGVSIGGLSGLSRALGDPITLGIVLGL
TH_3766|M.thermoresistible__bu EHFEHRLRPLSAGLAVPVFAFFAAGVDFGGLSGLGDALRDPVTLGIIGGL
MAB_2991c|M.abscessus_ATCC_199 EQFEHRLRPLSAGVAVPVFAFFAAGVTLGGFAGLGQALLDPVALGVVLGL
MSMEG_2775|M.smegmatis_MC2_155 DRMEHRLRPLSAGFAVPVFAFFAAGVTVGGLSGFASALSHPVTYGVIAGL
: :***:**:***.*:********** .**: *: ** .*:: *:: **
Mflv_3924|M.gilvum_PYR-GCK VLGKPIGIVLTTRVLSAVTRANLDASLRWVDVVGMSMLAGIGFTVSLLIG
Mvan_2476|M.vanbaalenii_PYR-1 VAGKPIGILVTTRVLSAVTRASLDSSLRWVDVLGMSMLAGIGFTVSLLIG
TH_3766|M.thermoresistible__bu VVGKPVGIWLTTRLLAAFTRARLDATLRWVDVFGVSLLAGIGFTVSLLIG
MAB_2991c|M.abscessus_ATCC_199 LVGKPVGVFLTTYLLARFTRASLDDDLSWLDIAGVALLAGIGFTVSLLIG
MSMEG_2775|M.smegmatis_MC2_155 VLGKPIGVFLTTYVLARFTNASLDEDLAWRDVLGLALLAGIGFTVSLLIG
: ***:*: :** :*: .*.* ** * * *: *:::*************
Mflv_3924|M.gilvum_PYR-GCK DLAY--------GLGSERDEFVKIGVLFGSLLAAGVAAVVLLTRNRAYRR
Mvan_2476|M.vanbaalenii_PYR-1 DLAF--------GMGSERDEFVKIGVLSGSLLAASLAAIVLLTRNRAYRR
TH_3766|M.thermoresistible__bu DLAY--------GTGSIRDDHVKVGVLLGSVTAAALAAAVLRMRNRYYRI
MAB_2991c|M.abscessus_ATCC_199 ELAFGAAESATSGVGAETASHVKVGVLAGSLTSAAVASVVLRLRNRVYQR
MSMEG_2775|M.smegmatis_MC2_155 ELAFE--------NSPIAHDDAKIAVLTGSVLAGLLAAVVLLSRNAVYRR
:**: .. . .*:.** **: :. :*: ** ** *:
Mflv_3924|M.gilvum_PYR-GCK IYREETVDEDRDGVPDVYQTRQDRT-
Mvan_2476|M.vanbaalenii_PYR-1 IHREETADDDHDGVPDVYQTRQD---
TH_3766|M.thermoresistible__bu LHQQETEDADRDGVPDIYQSPNT---
MAB_2991c|M.abscessus_ATCC_199 IEAKETLDADHDGVPDVFGSAPGDRI
MSMEG_2775|M.smegmatis_MC2_155 IHEAETVDADDDGVPDIYQPRQDQ--
: ** * * *****:: .