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M. vanbaalenii PYR-1 Mvan_2476 (nhaA)

annotation: Na+/H+ antiporter NhaA
coordinates: 2627804 - 2629198
length: 464

VCREDWSASIRRRPVRQAVTSDPRARRIRRALLARGSWSETNRVTEILRKETVGGIILLVAAAAALIWAN
SPWSQSYFALRDFELGGEWLGLHLNLTLGAWAADGLLAIFFLVVGLELKREFVAGDLRDPSRAALPIAAA
VGGMVVPALIFVLVNLNTGDGALRGWAIPTATDIAFAVAVLAVISTHLPSALRTFLLTLAVVDDLLAITV
IAVFYTDDIKAWALALAVVPLALFTVCAQRGVQKWWLLVPLSVATWVLVHESGVHATVAGVLLGFAVPVH
RSATRRGQQVDHAERVGMAEYFEHRVRPISAGIAIPVFAFFAAGVSIGGLSGLSRALGDPITLGIVLGLV
AGKPIGILVTTRVLSAVTRASLDSSLRWVDVLGMSMLAGIGFTVSLLIGDLAFGMGSERDEFVKIGVLSG
SLLAASLAAIVLLTRNRAYRRIHREETADDDHDGVPDVYQTRQD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2476nhaA-100% (464)Na+/H+ antiporter NhaA
M. vanbaalenii PYR-1Mvan_0667-8e-6336.56% (413) Na+/H+ antiporter NhaA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3924nhaA0.087.61% (436) Na+/H+ antiporter NhaA
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2991c-1e-16065.08% (441) Na+/H+ antiporter NhaA
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_2775nhaA1e-14863.16% (437) Na+/H+ antiporter NhaA
M. thermoresistible (build 8)TH_3766-0.074.08% (436) PUTATIVE Na+/H+ antiporter NhaA
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_2476|M.vanbaalenii_PYR-1       MCREDWSASIRRRPVRQAVTSDPRARRIRRALLARGSWSETNRVTEILRK
Mflv_3924|M.gilvum_PYR-GCK          ----------------MAATPLPPPR---RPVFSRGSWAETRRVTEILRK
TH_3766|M.thermoresistible__bu      ----------------VIARPLRRPP---RRLLTRGSWAETSRITAILRR
MAB_2991c|M.abscessus_ATCC_199      ----------------MRLS---------QRVFTRGSWAESSRVAEILRK
MSMEG_2775|M.smegmatis_MC2_155      ----------------MTDQPETFR----RRIFSRSSWPEWQRVSELLRT
                                                                 : :::*.**.*  *:: :** 

Mvan_2476|M.vanbaalenii_PYR-1       ETVGGIILLVAAAAALIWANSPWSQSYFALRDFELGGEWLGLHLNLTLGA
Mflv_3924|M.gilvum_PYR-GCK          ETVGGVILLVAAAAALIWANSPWAEGYFALRDLELGGEWFGLHLNLTLGA
TH_3766|M.thermoresistible__bu      ETVGGGVLLVVAAAALLWANSPWSAGYFGLRDATVGGEPLGLHLNLTVGT
MAB_2991c|M.abscessus_ATCC_199      ETVGGVLLVVAAVAALLWANSPWSSWYYRLGAITVGPE--QLHLHLTLAG
MSMEG_2775|M.smegmatis_MC2_155      ETVGGALLLVAALAALVWANSPWSAGYDQVSDFVVGPH--SLHLDLSISA
                                    ***** :*:*.* ***:******:  *  :    :* .   ***.*::. 

Mvan_2476|M.vanbaalenii_PYR-1       WAADGLLAIFFLVVGLELKREFVAGDLRDPSRAALPIAAAVGGMVVPALI
Mflv_3924|M.gilvum_PYR-GCK          WAADGLLAIFFLVVGLELKREFVAGDLRDPSRAALPIAAAVGGMVVPALI
TH_3766|M.thermoresistible__bu      WAADGLLAIFFLVVGLELKREFVAGDLRDPARAVLPIVAAVGGMVAPALI
MAB_2991c|M.abscessus_ATCC_199      WATDGLLAIFFFVVGVELKREFVAGDLRDPGRAALPIVAAVGGMLVPAAI
MSMEG_2775|M.smegmatis_MC2_155      WAADGLLAIFFFVVGVELKREFVVGDLRDPAKAALPIAAAVGGMIVPAVI
                                    **:********:***:*******.******.:*.***.******:.** *

Mvan_2476|M.vanbaalenii_PYR-1       FVLVNLNTGD-GALRGWAIPTATDIAFAVAVLAVISTHLPSALRTFLLTL
Mflv_3924|M.gilvum_PYR-GCK          FVLVNLNTGD-GALRGWAIPTATDIAFAVAVLAVIGTHLPSALRTFLLTL
TH_3766|M.thermoresistible__bu      FVVVAAGGGE-GALRGWAIPTATDIAFAVAVLAVLSTHLPAALRTFLLTL
MAB_2991c|M.abscessus_ATCC_199      YLAVNASGGG-AAMRGWAIPTATDIAFALAVLAVISTHLPTALRTFLLTL
MSMEG_2775|M.smegmatis_MC2_155      FVGVNLVAGHTENLGGWAIPVATDIAFALAVLAVIATHLPSALRIFLLTL
                                    :: *    *    : *****.*******:*****:.****:*** *****

Mvan_2476|M.vanbaalenii_PYR-1       AVVDDLLAITVIAVFYTDDIKAWALALAVVPLALFTVCAQRGVQKWWLLV
Mflv_3924|M.gilvum_PYR-GCK          AVVDDLLAITVIAVFYTEDINGLALALAAVPLALFALCVQRGVQKWWVLV
TH_3766|M.thermoresistible__bu      AVVDDLLAVTVIAVFYTEEINTTALGLTLVPLAAFTVCVQRRIRAWWLLI
MAB_2991c|M.abscessus_ATCC_199      AVVDDLLAVIVIAVFYTDELHWGPLGLALVPLGLFALAVQRRRREWWLLV
MSMEG_2775|M.smegmatis_MC2_155      AVVDDLLAIIVIAVFYTTQLSFGPLAGALVTIAVFGLAVQRGVRTPFLLL
                                    ********: ******* ::   .*. : *.:. * :..**  :  ::*:

Mvan_2476|M.vanbaalenii_PYR-1       PLSVATWVLVHESGVHATVAGVLLGFAVPVHRSATRRGQQVDHAERVGMA
Mflv_3924|M.gilvum_PYR-GCK          PLSVATWVLMHESGVHATVAGVLLGFAVPVRRQATPRGRGPAPSQRVGMA
TH_3766|M.thermoresistible__bu      PLGVATWVLMHESGVHATVAGVLLGFAVPVRRSAAAGG----PAAGPGMA
MAB_2991c|M.abscessus_ATCC_199      PLAVATWALVHASGVHATVAGVLLGFTVPVLR---RDG----RTDAHGMA
MSMEG_2775|M.smegmatis_MC2_155      PLAVVAWALMHASGVHATVAGVLLGFTIPVLG-------------RHACA
                                    **.*.:*.*:* **************::**                 . *

Mvan_2476|M.vanbaalenii_PYR-1       EYFEHRVRPISAGIAIPVFAFFAAGVSIGGLSGLSRALGDPITLGIVLGL
Mflv_3924|M.gilvum_PYR-GCK          EYFEHRVRPVSAGIAIPVFAFFAAGVSIGGLDGFTRALSDPITLGIVLGL
TH_3766|M.thermoresistible__bu      EHFEHRLRPLSAGLAVPVFAFFAAGVDFGGLSGLGDALRDPVTLGIIGGL
MAB_2991c|M.abscessus_ATCC_199      EQFEHRLRPLSAGVAVPVFAFFAAGVTLGGFAGLGQALLDPVALGVVLGL
MSMEG_2775|M.smegmatis_MC2_155      DRMEHRLRPLSAGFAVPVFAFFAAGVTVGGLSGFASALSHPVTYGVIAGL
                                    : :***:**:***.*:********** .**: *:  ** .*:: *:: **

Mvan_2476|M.vanbaalenii_PYR-1       VAGKPIGILVTTRVLSAVTRASLDSSLRWVDVLGMSMLAGIGFTVSLLIG
Mflv_3924|M.gilvum_PYR-GCK          VLGKPIGIVLTTRVLSAVTRANLDASLRWVDVVGMSMLAGIGFTVSLLIG
TH_3766|M.thermoresistible__bu      VVGKPVGIWLTTRLLAAFTRARLDATLRWVDVFGVSLLAGIGFTVSLLIG
MAB_2991c|M.abscessus_ATCC_199      LVGKPVGVFLTTYLLARFTRASLDDDLSWLDIAGVALLAGIGFTVSLLIG
MSMEG_2775|M.smegmatis_MC2_155      VLGKPIGVFLTTYVLARFTNASLDEDLAWRDVLGLALLAGIGFTVSLLIG
                                    : ***:*: :** :*: .*.* **  * * *: *:::*************

Mvan_2476|M.vanbaalenii_PYR-1       DLAF--------GMGSERDEFVKIGVLSGSLLAASLAAIVLLTRNRAYRR
Mflv_3924|M.gilvum_PYR-GCK          DLAY--------GLGSERDEFVKIGVLFGSLLAAGVAAVVLLTRNRAYRR
TH_3766|M.thermoresistible__bu      DLAY--------GTGSIRDDHVKVGVLLGSVTAAALAAAVLRMRNRYYRI
MAB_2991c|M.abscessus_ATCC_199      ELAFGAAESATSGVGAETASHVKVGVLAGSLTSAAVASVVLRLRNRVYQR
MSMEG_2775|M.smegmatis_MC2_155      ELAFE--------NSPIAHDDAKIAVLTGSVLAGLLAAVVLLSRNAVYRR
                                    :**:          ..   . .*:.** **: :. :*: **  **  *: 

Mvan_2476|M.vanbaalenii_PYR-1       IHREETADDDHDGVPDVYQTRQD---
Mflv_3924|M.gilvum_PYR-GCK          IYREETVDEDRDGVPDVYQTRQDRT-
TH_3766|M.thermoresistible__bu      LHQQETEDADRDGVPDIYQSPNT---
MAB_2991c|M.abscessus_ATCC_199      IEAKETLDADHDGVPDVFGSAPGDRI
MSMEG_2775|M.smegmatis_MC2_155      IHEAETVDADDDGVPDIYQPRQDQ--
                                    :   ** * * *****:: .