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M. thermoresistible (build 8) TH_3590 (-)

annotation: putative hypothetical protein MSMEG_5421
coordinates: 4078245 - 4080641
length: 799

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3590--100% (799)putative hypothetical protein MSMEG_5421
M. thermoresistible (build 8)TH_3772-2e-3033.95% (377) PUTATIVE putative AAA ATPase containing von Willebrand factor
M. thermoresistible (build 8)TH_2700-2e-2534.41% (279) PUTATIVE putative AAA ATPase containing von Willebrand factor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2640PPE423e-0925.73% (241) PPE family protein
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2608PPE423e-0925.73% (241) PPE family protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4141-5e-0529.58% (142) PE/PPE family protein
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_5421-1e-11648.84% (475) hypothetical protein MSMEG_5421
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


TH_3590|M.thermoresistible__bu      MQNARARRRRIRRLKATKVALAGASAATAVAVGLTPFMANAAVSETQVIG
MSMEG_5421|M.smegmatis_MC2_155      ---------------MTKAAVVGTAIAATLGVGITPTMANAVSSDTYFIG
Mb2640|M.bovis_AF2122/97            -------------MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLAEE
Rv2608|M.tuberculosis_H37Rv         -------------MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLAEE
MAB_4141|M.abscessus_ATCC_1997      -------------MAGQYSVPGKRHSLRRYVATITAVAATCTVLAPLAME
                                                                   . : .  * .         

TH_3590|M.thermoresistible__bu      LPGWLPIDIPGVNLLPADPAAINGAVAALRDTDPITGLPTQLLGLP----
MSMEG_5421|M.smegmatis_MC2_155      FPDWLPIGAS--NSVDADADAIYQAIVGSKDTSPLVGWGTGGVALDPKWV
Mb2640|M.bovis_AF2122/97            LHAAAGSFASVTTGLAGDAWHGPASLAMTRAASPYVGWLN----------
Rv2608|M.tuberculosis_H37Rv         LHAAAGSFASVTTGLAGDAWHGPASLAMTRAASPYVGWLN----------
MAB_4141|M.abscessus_ATCC_1997      SRTIASTLASYVIGIGGNNDGASANIPRKLGGAYSVDYHP----------
                                             .    : .:       :         ..             

TH_3590|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5421|M.smegmatis_MC2_155      QWYNPNLGGLDLSDIDLGDLSTGDLAALLTKMDLGELTNSDNDQYYTPPK
Mb2640|M.bovis_AF2122/97            --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4141|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_3590|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5421|M.smegmatis_MC2_155      WGQTGTKDVLVDNPEYQAAFEEALAEVMAQDREAILAADKINLTISYQVP
Mb2640|M.bovis_AF2122/97            --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4141|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_3590|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5421|M.smegmatis_MC2_155      EPSWWKEGYLGFSLSSIFGSWANQKINGQSVTSIATTVSIDNPFKNDPAA
Mb2640|M.bovis_AF2122/97            --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4141|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_3590|M.thermoresistible__bu      ------------ATPSVAIGPVWHTSLEWRADFFN---------------
MSMEG_5421|M.smegmatis_MC2_155      LDKFLETGKYDGTYTVPTINPVTALGLKRPSGYLAGAAYDYIVKTWLKPI
Mb2640|M.bovis_AF2122/97            ------------TAAGQAAQAAGQARLAASA-------------------
Rv2608|M.tuberculosis_H37Rv         ------------TAAGQAAQAAGQARLAASA-------------------
MAB_4141|M.abscessus_ATCC_1997      ------------VSYPGAIWPVSGLTAPTFK-------------------
                                                .    :  ..                            

TH_3590|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5421|M.smegmatis_MC2_155      NIDPVNYTFDRTKFNLPGGSWEERAEDLVDPTIPQQIPETQPVFGWLPGG
Mb2640|M.bovis_AF2122/97            --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4141|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_3590|M.thermoresistible__bu      FETVVRGQWIDP-------------------------------RREPLFH
MSMEG_5421|M.smegmatis_MC2_155      WTTNTFGQWVSPTDQLANLDLSALAGLANGDFDLSTLAGLANLSPQTIAY
Mb2640|M.bovis_AF2122/97            -FEATLAATVSP--------------------------------------
Rv2608|M.tuberculosis_H37Rv         -FEATLAATVSP--------------------------------------
MAB_4141|M.abscessus_ATCC_1997      -TSVAQGRTNLN--------------------------------------
                                        . .                                           

TH_3590|M.thermoresistible__bu      LAESLALEVAPALNWTWYLQNANLIAYGDGAIAAGLAYQAIIDAVGAGDW
MSMEG_5421|M.smegmatis_MC2_155      FLSGDLGFLAPLLNWTLYAQNINLIAYGDGAIATGEAYRRFIEAVTSGEI
Mb2640|M.bovis_AF2122/97            ------AMVAANRTRLASLVAANLLGQNAPAIAAAEAEYEQIWAQDVAAM
Rv2608|M.tuberculosis_H37Rv         ------AMVAANRTRLASLVAANLLGQNAPAIAAAEAEYEQIWAQDVAAM
MAB_4141|M.abscessus_ATCC_1997      -----------DEIVTAGNQPITIVGYSLGAVVVSKSHSDLLQRYPGG--
                                                          .::. .  *:... :    :     .  

TH_3590|M.thermoresistible__bu      VVGVPLTDPRDILVPG------------ASSPDPDDPDFRNPIHQQIHPG
MSMEG_5421|M.smegmatis_MC2_155      KAGEPRTDGRYIVFDVDEDGNPILKVVNHSTGNGGLDDIIVSYPLPNDLE
Mb2640|M.bovis_AF2122/97            FG--------------------------YHSAASAVATQLAPIQEGLQQQ
Rv2608|M.tuberculosis_H37Rv         FG--------------------------YHSAASAVATQLAPIQEGLQQQ
MAB_4141|M.abscessus_ATCC_1997      -------------------------------------------NPNIQFV
                                                                                   .  

TH_3590|M.thermoresistible__bu      WVDPGMSPRGEPVWR--VVKPGGVIDISLLSLILLRNPGRPNGGLYARFA
MSMEG_5421|M.smegmatis_MC2_155      FPDMPVDANGNPLYPSYTETPGGVIDVTLMTLALLRNPGRPNGGLYARFA
Mb2640|M.bovis_AF2122/97            LQNVLAQLASGNLGS-------GNVGVGNIGNDNIGNAN-------IGFG
Rv2608|M.tuberculosis_H37Rv         LQNVLAQLASGNLGS-------GNVGVGNIGNDNIGNAN-------IGFG
MAB_4141|M.abscessus_ATCC_1997      LMGSANTPNGGIFAR---------FPWLKIPLADIESNG--------AWE
                                      .      .  .           .    :    : . .         : 

TH_3590|M.thermoresistible__bu      PIYEAVRGVDPVSPERIDALPAGVDPDLIARLLTGDTSGLTADDLGALLE
MSMEG_5421|M.smegmatis_MC2_155      PIYQELTGVNPVSPERKDVLYG-LPDDTVTKLLKGDVSGIGLSDLNDLLV
Mb2640|M.bovis_AF2122/97            NRGDANIGIGNIG-DRNLGIGNTGNWNIGIGITGNGQIGFGKPANPDVLV
Rv2608|M.tuberculosis_H37Rv         NRGDANIGIGNIG-DRNLGIGNTGNWNIGIGITGNGQIGFGKPANPDVLV
MAB_4141|M.abscessus_ATCC_1997      P-DQFKTKVINTEYDTYGDFPAYFNPLALANSIAAIQYAHPDAYYDRIDP
                                       :    :     :    :                  .        :  

TH_3590|M.thermoresistible__bu      ALATDGDGKPTVVTAKVDATWAYDILSDAPATANPVAWLNSLASGIFLTN
MSMEG_5421|M.smegmatis_MC2_155      FLN-DADGKPMVITIKADATWEYDLLSDAPVTANPIAWANSVASSMLVFT
Mb2640|M.bovis_AF2122/97            VGN----GGPGVTALVMGGTDSLLSLPNIPLLEYAARFITPVHP------
Rv2608|M.tuberculosis_H37Rv         VGN----GGPGVTALVMGGTDSLLPLPNIPLLEYAARFITPVHP------
MAB_4141|M.abscessus_ATCC_1997      AALDDPDNPNVVKTVQGNTTYYLVRAEHLPLLQPLRDLTNPIGAS-----
                                           .   * :   . *       . *         ..: .      

TH_3590|M.thermoresistible__bu      LLTGIDPTNPGGAPDGFTLSMYVVPVGERDAGTVYLTYAPNQLPLLAPLR
MSMEG_5421|M.smegmatis_MC2_155      YGAELINMATN-REGGVGVVAYQVPDGEYDAGSFYATLTSQGLPLLAPAR
Mb2640|M.bovis_AF2122/97            ---------------GYTATFLETP--------------SQFFPFTGLNS
Rv2608|M.tuberculosis_H37Rv         ---------------GYTATFLETP--------------SQFFPFTGLNS
MAB_4141|M.abscessus_ATCC_1997      ----------------FVLDAIEPT-----------------------LR
                                                            .                         

TH_3590|M.thermoresistible__bu      LPAQLLSLVTGEDINTPVSDALEPFLRILTN-IAYDDVVRNPDGSWERTL
MSMEG_5421|M.smegmatis_MC2_155      LVAGLLSAATGEDVNTPLADALEPVLKLLVN-TSYTDAVRNEDGTWTRTL
Mb2640|M.bovis_AF2122/97            LTYDVSVAQGVTNLHTAIMAQLAAGNEVVVFGTSQSATIATFEMRYLQSL
Rv2608|M.tuberculosis_H37Rv         LTYDVSVAQGVTNLHTAIMAQLAAGNEVVVFGTSQSATIATFEMRYLQSL
MAB_4141|M.abscessus_ATCC_1997      VFIDMAYDRDTGPGTTTQFSFFTPSKNIVDAFNKLPTAIAEG--------
                                    :   :          *.    : .  .::        .:           

TH_3590|M.thermoresistible__bu      DRFHEAALFGTRTLTKDQALYLPGDLIAALGRGIGDELTDVLTRTLSRVV
MSMEG_5421|M.smegmatis_MC2_155      DQMHVPTLFGTQTISRQQAALLAGDILAEFGRGVGAEYTDVVQRVTARVV
Mb2640|M.bovis_AF2122/97            PAHLRPGLDELSFTLTGNPNRPDGGILTRFGFSIPQLGFTLSGATPADAY
Rv2608|M.tuberculosis_H37Rv         PAHLRPGLDELSFTLTGNPNRPDGGILTRFGFSIPQLGFTLSGATPADAY
MAB_4141|M.abscessus_ATCC_1997      AHNVENGLAGATPKQSASPEKPASPPVPQPGPTNPGSATTQIPAPEAPTP
                                           *         ..    .  :.  *               : . 

TH_3590|M.thermoresistible__bu      QFLNLFGIEVPQAQVEQLGELLGFPGEVIKTVSREIGTGVSELLHALEPV
MSMEG_5421|M.smegmatis_MC2_155      KFLEDNDIKVPTEIKEAAAKLATEPGKVIQTVSREVGTGVSKVLGAVDAK
Mb2640|M.bovis_AF2122/97            PTVDY------AFQYDGVNDFPKYPLNVFATAN--AIAGILFLHSGLIAL
Rv2608|M.tuberculosis_H37Rv         PTVDY------AFQYDGVNDFPKYPLNVFATAN--AIAGILFLHSGLIAL
MAB_4141|M.abscessus_ATCC_1997      SVVSLS---TAEPPAPPASAKAADPTAISVSTAGASTARDQDFQPDTKPD
                                      :.                    *  :  :.     :    .     . 

TH_3590|M.thermoresistible__bu      IPDLPAFTQSQLREGQSALAPVVAPVLQAADAIGSPIIAAAEDALGDVIR
MSMEG_5421|M.smegmatis_MC2_155      LPETPAPTQEQLAEGQKEVGQALAEVNEATEGAVTKGLKDTTAFINDPIT
Mb2640|M.bovis_AF2122/97            PPDLASGVVQPVSSPDVLTTYILLPSQDLPLLVPLRAIPLLGNPLADLIQ
Rv2608|M.tuberculosis_H37Rv         PPDLASGVVQPVSSPDVLTTYILLPSQDLPLLVPLRAIPLLGNPLADLIQ
MAB_4141|M.abscessus_ATCC_1997      PKSTPPPTKDSVGEADKSKNTLKPTLRLPKLPVAQPGTAPKSPKFPSLKN
                                      . .. . . : . :                            : .   

TH_3590|M.thermoresistible__bu      GLFESLAGGGTTTLLATGTENATAAEAKFVQVPEQPLTATAFGTNDPLPP
MSMEG_5421|M.smegmatis_MC2_155      ------------PVLKAGKDIESKVTKRITKTQNSLAKAQVRAG------
Mb2640|M.bovis_AF2122/97            ------------PDLRVLVELGYDRTAHQDVPSPFGLFPDVDWA------
Rv2608|M.tuberculosis_H37Rv         ------------PDLRVLVELGYDRTAHQDVPSPFGLFPDVDWA------
MAB_4141|M.abscessus_ATCC_1997      -------------HLKSVPGLSEKKNPAADASSKHSQPANAPAH------
                                                  *                       . .         

TH_3590|M.thermoresistible__bu      AEPNNAPVPQASEPEPTPAAELDTKLEHNTQNYAQNTARNNLGDSVQNTK
MSMEG_5421|M.smegmatis_MC2_155      ------------------------KVTEKLQKGDIKGAVKQVGENVQN-R
Mb2640|M.bovis_AF2122/97            ------------------------EVAADLQQGAVQGVNDALSGLGLPPP
Rv2608|M.tuberculosis_H37Rv         ------------------------EVAADLQQGAVQGVNDALSGLGLPPP
MAB_4141|M.abscessus_ATCC_1997      -------------------------TSDKTSDHASETGRGAA--------
                                                                . ..   :              

TH_3590|M.thermoresistible__bu      VQRLKPTLRRNDLNASPAGSPTWSSGVQADDNTGRELVGVTAVTDADRTT
MSMEG_5421|M.smegmatis_MC2_155      VDRLKKDINN----------------------------GVKKITGKDKTK
Mb2640|M.bovis_AF2122/97            WQPALPRLF-----------------------------------------
Rv2608|M.tuberculosis_H37Rv         WQPALPRLF-----------------------------------------
MAB_4141|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_3590|M.thermoresistible__bu      VAGQGDSTGRTTVKEETSADSSPED
MSMEG_5421|M.smegmatis_MC2_155      STS---SSSTDSDKDKGGSED----
Mb2640|M.bovis_AF2122/97            -------------------------
Rv2608|M.tuberculosis_H37Rv         -------------------------
MAB_4141|M.abscessus_ATCC_1997      -------------------------