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MTKAAVVGTAIAATLGVGITPTMANAVSSDTYFIGFPDWLPIGASNSVDADADAIYQAIVGSKDTSPLVG WGTGGVALDPKWVQWYNPNLGGLDLSDIDLGDLSTGDLAALLTKMDLGELTNSDNDQYYTPPKWGQTGTK DVLVDNPEYQAAFEEALAEVMAQDREAILAADKINLTISYQVPEPSWWKEGYLGFSLSSIFGSWANQKIN GQSVTSIATTVSIDNPFKNDPAALDKFLETGKYDGTYTVPTINPVTALGLKRPSGYLAGAAYDYIVKTWL KPINIDPVNYTFDRTKFNLPGGSWEERAEDLVDPTIPQQIPETQPVFGWLPGGWTTNTFGQWVSPTDQLA NLDLSALAGLANGDFDLSTLAGLANLSPQTIAYFLSGDLGFLAPLLNWTLYAQNINLIAYGDGAIATGEA YRRFIEAVTSGEIKAGEPRTDGRYIVFDVDEDGNPILKVVNHSTGNGGLDDIIVSYPLPNDLEFPDMPVD ANGNPLYPSYTETPGGVIDVTLMTLALLRNPGRPNGGLYARFAPIYQELTGVNPVSPERKDVLYGLPDDT VTKLLKGDVSGIGLSDLNDLLVFLNDADGKPMVITIKADATWEYDLLSDAPVTANPIAWANSVASSMLVF TYGAELINMATNREGGVGVVAYQVPDGEYDAGSFYATLTSQGLPLLAPARLVAGLLSAATGEDVNTPLAD ALEPVLKLLVNTSYTDAVRNEDGTWTRTLDQMHVPTLFGTQTISRQQAALLAGDILAEFGRGVGAEYTDV VQRVTARVVKFLEDNDIKVPTEIKEAAAKLATEPGKVIQTVSREVGTGVSKVLGAVDAKLPETPAPTQEQ LAEGQKEVGQALAEVNEATEGAVTKGLKDTTAFINDPITPVLKAGKDIESKVTKRITKTQNSLAKAQVRA GKVTEKLQKGDIKGAVKQVGENVQNRVDRLKKDINNGVKKITGKDKTKSTSSSSTDSDKDKGGSED
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5421 | - | - | 100% (976) | hypothetical protein MSMEG_5421 |
| M. smegmatis MC2 155 | MSMEG_0200 | - | 5e-31 | 28.44% (531) | hypothetical protein MSMEG_0200 |
| M. smegmatis MC2 155 | MSMEG_5502 | - | 2e-19 | 23.35% (544) | hypothetical protein MSMEG_5502 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2640 | PPE42 | 1e-05 | 25.59% (211) | PPE family protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2608 | PPE42 | 1e-05 | 25.59% (211) | PPE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3590 | - | 1e-116 | 48.84% (475) | PUTATIVE putative hypothetical protein MSMEG_5421 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5421|M.smegmatis_MC2_155 ---------------MTKAAVVGTAIAATLGVGITPTMANAVSSDTYFIG
TH_3590|M.thermoresistible__bu MQNARARRRRIRRLKATKVALAGASAATAVAVGLTPFMANAAVSETQVIG
Mb2640|M.bovis_AF2122/97 -------------MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLAEE
Rv2608|M.tuberculosis_H37Rv -------------MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLAEE
: . : ..*: * :* * :
MSMEG_5421|M.smegmatis_MC2_155 FPDWLPIGAS--NSVDADADAIYQAIVGSKDTSPLVGWGTGGVALDPKWV
TH_3590|M.thermoresistible__bu LPGWLPIDIPGVNLLPADPAAINGAVAALRDTDPITGLPTQLLGLP----
Mb2640|M.bovis_AF2122/97 LHAAAGSFASVTTGLAGDAWHGPASLAMTRAASPYVGWLN----------
Rv2608|M.tuberculosis_H37Rv LHAAAGSFASVTTGLAGDAWHGPASLAMTRAASPYVGWLN----------
: . . : .*. ::. : :.* .* .
MSMEG_5421|M.smegmatis_MC2_155 QWYNPNLGGLDLSDIDLGDLSTGDLAALLTKMDLGELTNSDNDQYYTPPK
TH_3590|M.thermoresistible__bu --------------------------------------------------
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5421|M.smegmatis_MC2_155 WGQTGTKDVLVDNPEYQAAFEEALAEVMAQDREAILAADKINLTISYQVP
TH_3590|M.thermoresistible__bu --------------------------------------------------
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5421|M.smegmatis_MC2_155 EPSWWKEGYLGFSLSSIFGSWANQKINGQSVTSIATTVSIDNPFKNDPAA
TH_3590|M.thermoresistible__bu --------------------------------------------------
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5421|M.smegmatis_MC2_155 LDKFLETGKYDGTYTVPTINPVTALGLKRPSGYLAGAAYDYIVKTWLKPI
TH_3590|M.thermoresistible__bu ------------ATPSVAIGPVWHTSLEWRADFFN---------------
Mb2640|M.bovis_AF2122/97 ------------TAAGQAAQAAGQARLAASA-------------------
Rv2608|M.tuberculosis_H37Rv ------------TAAGQAAQAAGQARLAASA-------------------
: . : .. * :
MSMEG_5421|M.smegmatis_MC2_155 NIDPVNYTFDRTKFNLPGGSWEERAEDLVDPTIPQQIPETQPVFGWLPGG
TH_3590|M.thermoresistible__bu --------------------------------------------------
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_5421|M.smegmatis_MC2_155 WTTNTFGQWVSPTDQLANLDLSALAGLANGDFDLSTLAGLANLSPQTIAY
TH_3590|M.thermoresistible__bu FETVVRGQWIDP-------------------------------RREPLFH
Mb2640|M.bovis_AF2122/97 -FEATLAATVSP--------------------------------------
Rv2608|M.tuberculosis_H37Rv -FEATLAATVSP--------------------------------------
. . :.*
MSMEG_5421|M.smegmatis_MC2_155 FLSGDLGFLAPLLNWTLYAQNINLIAYGDGAIATGEAYRRFIEAVTSGEI
TH_3590|M.thermoresistible__bu LAESLALEVAPALNWTWYLQNANLIAYGDGAIAAGLAYQAIIDAVGAGDW
Mb2640|M.bovis_AF2122/97 ------AMVAANRTRLASLVAANLLGQNAPAIAAAEAEYEQIWAQDVAAM
Rv2608|M.tuberculosis_H37Rv ------AMVAANRTRLASLVAANLLGQNAPAIAAAEAEYEQIWAQDVAAM
:*. . **:. . ***:. * * * .
MSMEG_5421|M.smegmatis_MC2_155 KAGEPRTDGRYIVFDVDEDGNPILKVVNHSTGNGGLDDIIVSYPLPNDLE
TH_3590|M.thermoresistible__bu VVGVPLTDPRDILVPG------------ASSPDPDDPDFRNPIHQQIHPG
Mb2640|M.bovis_AF2122/97 FG--------------------------YHSAASAVATQLAPIQEGLQQQ
Rv2608|M.tuberculosis_H37Rv FG--------------------------YHSAASAVATQLAPIQEGLQQQ
: . .
MSMEG_5421|M.smegmatis_MC2_155 FPDMPVDANGNPLYPSYTETPGGVIDVTLMTLALLRNPGRPNGGLYARFA
TH_3590|M.thermoresistible__bu WVDPGMSPRGEPVWR--VVKPGGVIDISLLSLILLRNPGRPNGGLYARFA
Mb2640|M.bovis_AF2122/97 LQNVLAQLASGNLGS-------GNVGVGNIGNDNIGNAN-------IGFG
Rv2608|M.tuberculosis_H37Rv LQNVLAQLASGNLGS-------GNVGVGNIGNDNIGNAN-------IGFG
: . . : * :.: : : *.. *.
MSMEG_5421|M.smegmatis_MC2_155 PIYQELTGVNPVSPERKDVLYG-LPDDTVTKLLKGDVSGIGLSDLNDLLV
TH_3590|M.thermoresistible__bu PIYEAVRGVDPVSPERIDALPAGVDPDLIARLLTGDTSGLTADDLGALLE
Mb2640|M.bovis_AF2122/97 NRGDANIGIGNIG-DRNLGIGNTGNWNIGIGITGNGQIGFGKPANPDVLV
Rv2608|M.tuberculosis_H37Rv NRGDANIGIGNIG-DRNLGIGNTGNWNIGIGITGNGQIGFGKPANPDVLV
: *:. :. :* : : : .. *: :*
MSMEG_5421|M.smegmatis_MC2_155 FLN-DADGKPMVITIKADATWEYDLLSDAPVTANPIAWANSVASSMLVFT
TH_3590|M.thermoresistible__bu ALATDGDGKPTVVTAKVDATWAYDILSDAPATANPVAWLNSLASGIFLTN
Mb2640|M.bovis_AF2122/97 VGN----GGPGVTALVMGGTDSLLSLPNIPLLEYAARFITPVHP------
Rv2608|M.tuberculosis_H37Rv VGN----GGPGVTALVMGGTDSLLPLPNIPLLEYAARFITPVHP------
* * * : ..* *.: * . : ..: .
MSMEG_5421|M.smegmatis_MC2_155 YGAELINMATN-REGGVGVVAYQVPDGEYDAGSFYATLTSQGLPLLAPAR
TH_3590|M.thermoresistible__bu LLTGIDPTNPGGAPDGFTLSMYVVPVGERDAGTVYLTYAPNQLPLLAPLR
Mb2640|M.bovis_AF2122/97 ---------------GYTATFLETP--------------SQFFPFTGLNS
Rv2608|M.tuberculosis_H37Rv ---------------GYTATFLETP--------------SQFFPFTGLNS
* .* .: :*: .
MSMEG_5421|M.smegmatis_MC2_155 LVAGLLSAATGEDVNTPLADALEPVLKLLVN-TSYTDAVRNEDGTWTRTL
TH_3590|M.thermoresistible__bu LPAQLLSLVTGEDINTPVSDALEPFLRILTN-IAYDDVVRNPDGSWERTL
Mb2640|M.bovis_AF2122/97 LTYDVSVAQGVTNLHTAIMAQLAAGNEVVVFGTSQSATIATFEMRYLQSL
Rv2608|M.tuberculosis_H37Rv LTYDVSVAQGVTNLHTAIMAQLAAGNEVVVFGTSQSATIATFEMRYLQSL
* : :::*.: * . .::. : .: . : : ::*
MSMEG_5421|M.smegmatis_MC2_155 DQMHVPTLFGTQTISRQQAALLAGDILAEFGRGVGAEYTDVVQRVTARVV
TH_3590|M.thermoresistible__bu DRFHEAALFGTRTLTKDQALYLPGDLIAALGRGIGDELTDVLTRTLSRVV
Mb2640|M.bovis_AF2122/97 PAHLRPGLDELSFTLTGNPNRPDGGILTRFGFSIPQLGFTLSGATPADAY
Rv2608|M.tuberculosis_H37Rv PAHLRPGLDELSFTLTGNPNRPDGGILTRFGFSIPQLGFTLSGATPADAY
. * :. *.::: :* .: : . : .
MSMEG_5421|M.smegmatis_MC2_155 KFLEDNDIKVPTEIKEAAAKLATEPGKVIQTVSREVGTGVSKVLGAVDAK
TH_3590|M.thermoresistible__bu QFLNLFGIEVPQAQVEQLGELLGFPGEVIKTVSREIGTGVSELLHALEPV
Mb2640|M.bovis_AF2122/97 PTVDY------AFQYDGVNDFPKYPLNVFATAN--AIAGILFLHSGLIAL
Rv2608|M.tuberculosis_H37Rv PTVDY------AFQYDGVNDFPKYPLNVFATAN--AIAGILFLHSGLIAL
:: : .: * :*: *.. :*: : .: .
MSMEG_5421|M.smegmatis_MC2_155 LPETPAPTQEQLAEGQKEVGQALAEVNEATEGAVTKGLKDTTAFINDPIT
TH_3590|M.thermoresistible__bu IPDLPAFTQSQLREGQSALAPVVAPVLQAADAIGSPIIAAAEDALGDVIR
Mb2640|M.bovis_AF2122/97 PPDLASGVVQPVSSPDVLTTYILLPSQDLPLLVPLRAIPLLGNPLADLIQ
Rv2608|M.tuberculosis_H37Rv PPDLASGVVQPVSSPDVLTTYILLPSQDLPLLVPLRAIPLLGNPLADLIQ
*: .: . . : . : : : . : : * *
MSMEG_5421|M.smegmatis_MC2_155 ------------PVLKAGKDIESKVTKRITKTQNSLAKAQVRAG------
TH_3590|M.thermoresistible__bu GLFESLAGGGTTTLLATGTENATAAEAKFVQVPEQPLTATAFGTNDPLPP
Mb2640|M.bovis_AF2122/97 ------------PDLRVLVELGYDRTAHQDVPSPFGLFPDVDWA------
Rv2608|M.tuberculosis_H37Rv ------------PDLRVLVELGYDRTAHQDVPSPFGLFPDVDWA------
. * . : : . .
MSMEG_5421|M.smegmatis_MC2_155 ------------------------KVTEKLQKGDIKGAVKQVGENVQN-R
TH_3590|M.thermoresistible__bu AEPNNAPVPQASEPEPTPAAELDTKLEHNTQNYAQNTARNNLGDSVQNTK
Mb2640|M.bovis_AF2122/97 ------------------------EVAADLQQGAVQGVNDALSGLGLPPP
Rv2608|M.tuberculosis_H37Rv ------------------------EVAADLQQGAVQGVNDALSGLGLPPP
:: . *: : . . :.
MSMEG_5421|M.smegmatis_MC2_155 VDRLKKDINN----------------------------GVKKITGKDKTK
TH_3590|M.thermoresistible__bu VQRLKPTLRRNDLNASPAGSPTWSSGVQADDNTGRELVGVTAVTDADRTT
Mb2640|M.bovis_AF2122/97 WQPALPRLF-----------------------------------------
Rv2608|M.tuberculosis_H37Rv WQPALPRLF-----------------------------------------
: :
MSMEG_5421|M.smegmatis_MC2_155 STS---SSSTDSDKDKGGSED----
TH_3590|M.thermoresistible__bu VAGQGDSTGRTTVKEETSADSSPED
Mb2640|M.bovis_AF2122/97 -------------------------
Rv2608|M.tuberculosis_H37Rv -------------------------