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M. thermoresistible (build 8) TH_3445 (-)

annotation: beta-ketoacyl synthase
coordinates: 685430 - 686680
length: 417

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3445--100% (417)beta-ketoacyl synthase
M. thermoresistible (build 8)TH_2837-e-14963.46% (405) PUTATIVE beta-ketoacyl synthase
M. thermoresistible (build 8)TH_3425-e-13057.57% (403) PUTATIVE beta-ketoacyl synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2270kasB1e-15665.71% (417) 3-oxoacyl-(acyl carrier protein) synthase II
M. gilvum PYR-GCKMflv_2776-1e-15363.55% (417) 3-oxoacyl-(acyl carrier protein) synthase II
M. tuberculosis H37RvRv2246kasB1e-15665.71% (417) 3-oxoacyl-(acyl carrier protein) synthase II
M. leprae Br4923MLBr_01656kasB1e-15163.59% (412) 3-oxoacyl-(acyl carrier protein) synthase II
M. abscessus ATCC 19977MAB_1877c-1e-13257.46% (409) 3-oxoacyl-(acyl carrier protein) synthase II
M. marinum MMMAR_3339kasB1e-15263.07% (417) 3-oxoacyl-
M. avium 104MAV_2191-1e-14962.53% (419) 3-oxoacyl-(acyl carrier protein) synthase II
M. smegmatis MC2 155MSMEG_1204-1e-16366.75% (415) 3-oxoacyl-(acyl carrier protein) synthase II
M. ulcerans Agy99MUL_1303kasB1e-15263.07% (417) 3-oxoacyl-(acyl carrier protein) synthase II
M. vanbaalenii PYR-1Mvan_3757-1e-15362.83% (417) 3-oxoacyl-(acyl carrier protein) synthase II

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3339|M.marinum_M               ---------------------MTELVTGK-AFPHVVVTGIAMTTALATDA
MUL_1303|M.ulcerans_Agy99           ---------------------MTELVTGK-AFPHVVVTGIAMTTALATDA
Mb2270|M.bovis_AF2122/97            MGVPPLAGASRTDMEGTFARPMTELVTGK-AFPYVVVTGIAMTTALATDA
Rv2246|M.tuberculosis_H37Rv         MGVPPLAGASRTDMEGTFARPMTELVTGK-AFPYVVVTGIAMTTALATDA
MLBr_01656|M.leprae_Br4923          -------------MIARLMTTSPELVTGK-AFPNVVVTGIAMTTALATDA
MAV_2191|M.avium_104                MRAATARKVAGQVREGIFARPMTELVTGK-TLPNVVVTGIAMTTALATDA
Mflv_2776|M.gilvum_PYR-GCK          ---------------------MASPTTGN-GLPDVVVTGIAMTTALATDA
Mvan_3757|M.vanbaalenii_PYR-1       ---------------------MASPTTGN-GLPDVVVTGIAMTTSLATDA
MAB_1877c|M.abscessus_ATCC_199      ---------------------MTLPSTANGGFPNVVVTALAATTSIAPDI
TH_3445|M.thermoresistible__bu      ---------------------MVSMRTGD-GFRNVVVTAVAATTPLAADA
MSMEG_1204|M.smegmatis_MC2_155      ---------------------MVAKTTGN-GLPDVVVTAVASTTSLAPHA
                                                              *..  :  ****.:* **.:*.. 

MMAR_3339|M.marinum_M               ETTWKLLLDSQSGIRTLDDPFVEEFNLPVRIGGHLLEEFDHQLTRVELRR
MUL_1303|M.ulcerans_Agy99           ETTWKLLLDSQSGIRTLDDPFVEEFNLPVRIGGHLLEEFDHQLTRVELRR
Mb2270|M.bovis_AF2122/97            ETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIGGHLLEEFDHQLTRIELRR
Rv2246|M.tuberculosis_H37Rv         ETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIGGHLLEEFDHQLTRIELRR
MLBr_01656|M.leprae_Br4923          ETTWKLLLDNQSGIRMLDDPFIEEFNLPVRIGGHLLEEFDHQLTRVELRR
MAV_2191|M.avium_104                ETTWKLLLDSQSGIRTLDDPFVEEFDLPVRIGGHLLEEFDSQLTRVELRR
Mflv_2776|M.gilvum_PYR-GCK          EQTWTSLLDGRSGIRKLDDPFVEQFDLPVRIGGHLLEEFDAQLTKVENRR
Mvan_3757|M.vanbaalenii_PYR-1       EATWKSLLDGHSGIRKLQDPFVEEFDLPVQIGGHLLEEFDSQLTKVENRR
MAB_1877c|M.abscessus_ATCC_199      EGTWKGLIAGESGIEVLEDEFVEKFGLPVWIGGHLKEPIDNHMTRLELRR
TH_3445|M.thermoresistible__bu      EGTWAGLLAGDSGIRPLDRPFVTDFDSPVRIGGRLVENFADQLSRVELRR
MSMEG_1204|M.smegmatis_MC2_155      EDTWKLLLEGRSGIRALDKPFVEEFDSPVRIGGQLTEAFADKLGRVEQHR
                                    * **  *:   ***. *:  *: .*. ** ***:* * :  :: ::* :*

MMAR_3339|M.marinum_M               TAYLQRMSTVIGRRVWENAGSPE-VDTNRLAVSIGTGLGSAEELVFGYDE
MUL_1303|M.ulcerans_Agy99           TAYLQRMSTVIGRRVWENAGSPE-VDTNRLAVSIGTGLGSAEELVFGYDE
Mb2270|M.bovis_AF2122/97            MGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYDD
Rv2246|M.tuberculosis_H37Rv         MGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYDD
MLBr_01656|M.leprae_Br4923          MGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYDD
MAV_2191|M.avium_104                TGYLQRMSTILGRRVWENAGSPE-VDSNRLMVSIGTGLGSSEEMVFSYDD
Mflv_2776|M.gilvum_PYR-GCK          MSYIQKMATVLGRRVWENAGAPE-VDTERLLVSIGTGLGGAEALVFAYDG
Mvan_3757|M.vanbaalenii_PYR-1       MSYVQKMATVLGRRVWENAGSPE-VDTERLLVSIGTGLGGAEALVFAYDG
MAB_1877c|M.abscessus_ATCC_199      MAYVQRMALHVGRQVWQNAGSPDDIDKDRLGVVIGTGLGGGERIVETYDT
TH_3445|M.thermoresistible__bu      LGFMQQMSTLLSRRLWETAGNPD-VDTKRLLVSIGLALGSTEEIPIQHNA
MSMEG_1204|M.smegmatis_MC2_155      LSYMGQMSTVLGRRLWETAGNPE-VDTRRLMVSIGMALGTTEELILQYDL
                                     .:: :*:  :.*::*:.** *: :*. ** * ** .**  * :   :: 

MMAR_3339|M.marinum_M               MRVRGFRAISPLAVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGSEAI
MUL_1303|M.ulcerans_Agy99           MRVRGFRAISPLAVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGSEAI
Mb2270|M.bovis_AF2122/97            MRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAI
Rv2246|M.tuberculosis_H37Rv         MRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAI
MLBr_01656|M.leprae_Br4923          MRARGMKAVSPLAVQKYMPNGAAAAVGLEHHAKAGVMTPVSACASGSEAI
MAV_2191|M.avium_104                MRARGMKAVSPLGVQKYMPNGAAAAVGLEHHAKAGVITPVSACASGSEGI
Mflv_2776|M.gilvum_PYR-GCK          LRERGLRSVSPLSVQMYMPNGPSAVVGLERHAKAGVVTPVSACASGSEGI
Mvan_3757|M.vanbaalenii_PYR-1       LRERGLRSVSPLSVQMYMPNGPSAVVGLERHAKAGVVTPVSACASGSEGI
MAB_1877c|M.abscessus_ATCC_199      MNEHGIRKVSPLAVQMCMPNGAAAVVGLEIGARAGVITPVSACSSGSEAI
TH_3445|M.thermoresistible__bu      WKERGMRAISPLTVQMHMPNSAAAAVGLDRQAKAGVISPVMSDASGAAAI
MSMEG_1204|M.smegmatis_MC2_155      WKAKGLRAVPPTAIQKYMPNAPAAAVGLDRKAKAGIMSPIMADASGAAAI
                                     . :*:: :.*  :*  ***..:*.***:  *:**:::*: : :**: .*

MMAR_3339|M.marinum_M               ARAWQQVVLGEADIAICGGVETRIEAVPIAGFANMRIVMSTNNDDPAGAC
MUL_1303|M.ulcerans_Agy99           ARAWQQVVLGEADIAICGGVETRIEAVPIAGFANMRIVMSTNNDDPAGAC
Mb2270|M.bovis_AF2122/97            ARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGAC
Rv2246|M.tuberculosis_H37Rv         ARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGAC
MLBr_01656|M.leprae_Br4923          AHAWQQIVLGEADSAICGGVETKIEAVPIAGFSQMRIVMSTKNDNPAGAC
MAV_2191|M.avium_104                AQAWRNIVFGEADIAICGGVETKIEAVPIAAFAQMRIVMSTKNDDPVGAC
Mflv_2776|M.gilvum_PYR-GCK          AQAWRNIVMGEADIAICGGVEQRIEAVPIAAFAQMRIVMSTNNDDPAGAC
Mvan_3757|M.vanbaalenii_PYR-1       AQAWRNIVLGEADIAICGGVEQRIEAVPIAGFAQMRIVMSANNDDPAGAC
MAB_1877c|M.abscessus_ATCC_199      AHAWRQIVMGDADMIVCGGVEGMIEALPIAAFSMMR-AMSTRNDEPEKAS
TH_3445|M.thermoresistible__bu      TEAWRHIVLGEADVAICGGVETVVEAVPVACFTQLG-MLSTHNDDPAAAC
MSMEG_1204|M.smegmatis_MC2_155      AHAWREIILGDADIAICGGVETWIEAVPVGAFSQLG-MLSTYNDDPPAAC
                                    :.**:.:::*:**  :*****  :**:*:. *: :   :*: **:*  *.

MMAR_3339|M.marinum_M               RPFDKDRDGFVFGEGGALMVIETEEHAKARGANILARIMGASITSDGFHM
MUL_1303|M.ulcerans_Agy99           RPFDKDRDGFVFGEGGALMVIETEEHAKARGANILARIMGASITSDGFHM
Mb2270|M.bovis_AF2122/97            RPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHM
Rv2246|M.tuberculosis_H37Rv         RPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHM
MLBr_01656|M.leprae_Br4923          RPFDRDRDGFVFGEAGALMLIETEDSAKARSANILARIMGASITSDGFHM
MAV_2191|M.avium_104                RPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYHM
Mflv_2776|M.gilvum_PYR-GCK          RPFDKDRDGFVFGEAGALLVIETEEHAKARGATPLARLMGASITSDGFHM
Mvan_3757|M.vanbaalenii_PYR-1       RPFDKDRDGFVFGEAGALMVIETEEHARARGATPLARVMGASITSDGYHM
MAB_1877c|M.abscessus_ATCC_199      RPFDKDRDGFVFGEAGALMVIETEEHAKARGAQIIGRVMGAGITSDAYHM
TH_3445|M.thermoresistible__bu      RPFDQERDGMVFGEGGALLLIEAEEHAKARGATILARVMGGAITSDAYDP
MSMEG_1204|M.smegmatis_MC2_155      RPFDKDRDGMVLGEAGALMLVETEEHAKARGAPILARLMGAGMTNDCYDI
                                    ****::* *:*:**.***:::*:*: *:**.*  :.*:**..:*.* :. 

MMAR_3339|M.marinum_M               VAPDPNGERAGHAITRAVQLAGLQPSDIDHVNAHATGTQVGDVAEGRAIN
MUL_1303|M.ulcerans_Agy99           VAPDPNGERAGHAITRAVQLAGLQPSDIDHVNAHATGTQVGDVAEGRAIN
Mb2270|M.bovis_AF2122/97            VAPDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAIN
Rv2246|M.tuberculosis_H37Rv         VAPDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAIN
MLBr_01656|M.leprae_Br4923          VAPDPNGERAGHAIARAVHLAGLSPSDIDHVNAHATGTQVGDLAEAKAIN
MAV_2191|M.avium_104                VAPDPNGERAGHAMSRAIQLAGLTPGDIDHVNAHATGTSVGDVAESKAIN
Mflv_2776|M.gilvum_PYR-GCK          VAPDPDGERAGYAMTRAIELAGLTPTDIDHVNAHATGTSVGDVAEGRAIN
Mvan_3757|M.vanbaalenii_PYR-1       VAPDPNGERAGYAITRAIELAGLKPTDIDHVNAHATGTSVGDLAEGHAIN
MAB_1877c|M.abscessus_ATCC_199      VAPGPDGIRAGAAMTRAIQTAGLSPKDIDHINAHGTATPIGDVAEANAIH
TH_3445|M.thermoresistible__bu      IDLEPGGECAAEAIGRAIYLAGLEPTDIDHVNAHAAGTRTGDLAEAHALQ
MSMEG_1204|M.smegmatis_MC2_155      VKPDPDGQLAGDAIRRAIELAGLAPGDIDHINAHATGTDFGDLAEARAIH
                                    :   *.*  *. *: **:  *** * ****:***.:.*  **:**..*::

MMAR_3339|M.marinum_M               NALGSH--KPAVYAPKSALGHSVGAVGAVESILTVLALRDQVVPPTLNLV
MUL_1303|M.ulcerans_Agy99           NALGSH--KPAVYAPKSALGHSVGAVGAVESILTVLALRDQVVPPTLNLV
Mb2270|M.bovis_AF2122/97            NALGGN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLV
Rv2246|M.tuberculosis_H37Rv         NALGGN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLV
MLBr_01656|M.leprae_Br4923          KALCNN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLV
MAV_2191|M.avium_104                NALGPHGGNAAVYAPKAALGHSVGAVGAVESILTVLALRDQVVPPTLNLE
Mflv_2776|M.gilvum_PYR-GCK          RALGGH--RPAVYAPKSALGHSVGAVGAVESILTVQALRDGVVPPTLNLK
Mvan_3757|M.vanbaalenii_PYR-1       LAMGGH--RPAVYAPKSALGHSVGAVGAVESILTVQSLRDGIIPPTLNLK
MAB_1877c|M.abscessus_ATCC_199      VAGVQH---AAVYAPKSALGHSIGAVGALESVLTVLALRDGVIPPTLNLD
TH_3445|M.thermoresistible__bu      RVFGAH--RPAVYAPKAALGNALGAAGAIEAVLTVQALRDGVVPPTLNLK
MSMEG_1204|M.smegmatis_MC2_155      NVLGSH--RPSVYASKAALGHSLGSAGAVEAVLTVQTLRDGIVPATLNVK
                                     .   :   .:***.*:***:::*:.**:*::*** :*** ::*.***: 

MMAR_3339|M.marinum_M               NLDPEIDLDVVAGKPRPGNYRYAVNNSFGFGGHNVAITFGRY
MUL_1303|M.ulcerans_Agy99           NLDPEIDLDVVAGKPRPGNYRYAVNNSFGFGGHNVAITFGRY
Mb2270|M.bovis_AF2122/97            NLDPEIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY
Rv2246|M.tuberculosis_H37Rv         NLDPEIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY
MLBr_01656|M.leprae_Br4923          NLDPDIDLDVVAGKPRPGDYRYAVNNSFGFGGHNVAIAFGCY
MAV_2191|M.avium_104                NLDPEIDLDVVAGKPRPGNYQYAINNSFGFGGHNVAIAFGRY
Mflv_2776|M.gilvum_PYR-GCK          NQDPEIDLDVVAGSPRPGNYNYALNNSFGFGGHNVALAFGKY
Mvan_3757|M.vanbaalenii_PYR-1       NLDPEIDLDVVAGGPRPGNYEYAINNSFGFGGHNVALAFGKY
MAB_1877c|M.abscessus_ATCC_199      NLDPEIDLDVVAGEPRHGDFKYAINNSFGFGGHNVALAFGKY
TH_3445|M.thermoresistible__bu      NLDPEIDLDVVAGESRRGDYRYALTTSMGIGGHNVAVVFGAY
MSMEG_1204|M.smegmatis_MC2_155      NPDPQIDLDVVTDQPRSEHYRYALSNSFGLGGNNVVLAFGAA
                                    * **:******:. .*  .:.**:..*:*:**:**.:.**