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MVAKTTGNGLPDVVVTAVASTTSLAPHAEDTWKLLLEGRSGIRALDKPFVEEFDSPVRIGGQLTEAFADK LGRVEQHRLSYMGQMSTVLGRRLWETAGNPEVDTRRLMVSIGMALGTTEELILQYDLWKAKGLRAVPPTA IQKYMPNAPAAAVGLDRKAKAGIMSPIMADASGAAAIAHAWREIILGDADIAICGGVETWIEAVPVGAFS QLGMLSTYNDDPPAACRPFDKDRDGMVLGEAGALMLVETEEHAKARGAPILARLMGAGMTNDCYDIVKPD PDGQLAGDAIRRAIELAGLAPGDIDHINAHATGTDFGDLAEARAIHNVLGSHRPSVYASKAALGHSLGSA GAVEAVLTVQTLRDGIVPATLNVKNPDPQIDLDVVTDQPRSEHYRYALSNSFGLGGNNVVLAFGAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1204 | - | - | 100% (416) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. smegmatis MC2 155 | MSMEG_4328 | - | e-156 | 65.06% (415) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. smegmatis MC2 155 | MSMEG_4327 | - | e-134 | 56.83% (410) | 3-oxoacyl-(acyl carrier protein) synthase II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2270 | kasB | 1e-157 | 64.82% (415) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. gilvum PYR-GCK | Mflv_2776 | - | 1e-158 | 65.30% (415) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. tuberculosis H37Rv | Rv2246 | kasB | 1e-157 | 64.82% (415) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. leprae Br4923 | MLBr_01656 | kasB | 1e-152 | 63.66% (410) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. abscessus ATCC 19977 | MAB_1877c | - | 1e-131 | 55.96% (411) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. marinum M | MMAR_3339 | kasB | 1e-154 | 63.37% (415) | 3-oxoacyl- |
| M. avium 104 | MAV_2191 | - | 1e-153 | 63.07% (417) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. thermoresistible (build 8) | TH_3445 | - | 1e-163 | 66.75% (415) | PUTATIVE beta-ketoacyl synthase |
| M. ulcerans Agy99 | MUL_1303 | kasB | 1e-154 | 63.37% (415) | 3-oxoacyl-(acyl carrier protein) synthase II |
| M. vanbaalenii PYR-1 | Mvan_3757 | - | 1e-155 | 64.58% (415) | 3-oxoacyl-(acyl carrier protein) synthase II |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3339|M.marinum_M ---------------------MTELVTGK-AFPHVVVTGIAMTTALATDA
MUL_1303|M.ulcerans_Agy99 ---------------------MTELVTGK-AFPHVVVTGIAMTTALATDA
Mb2270|M.bovis_AF2122/97 MGVPPLAGASRTDMEGTFARPMTELVTGK-AFPYVVVTGIAMTTALATDA
Rv2246|M.tuberculosis_H37Rv MGVPPLAGASRTDMEGTFARPMTELVTGK-AFPYVVVTGIAMTTALATDA
MLBr_01656|M.leprae_Br4923 -------------MIARLMTTSPELVTGK-AFPNVVVTGIAMTTALATDA
MAV_2191|M.avium_104 MRAATARKVAGQVREGIFARPMTELVTGK-TLPNVVVTGIAMTTALATDA
Mflv_2776|M.gilvum_PYR-GCK ---------------------MASPTTGN-GLPDVVVTGIAMTTALATDA
Mvan_3757|M.vanbaalenii_PYR-1 ---------------------MASPTTGN-GLPDVVVTGIAMTTSLATDA
MAB_1877c|M.abscessus_ATCC_199 ---------------------MTLPSTANGGFPNVVVTALAATTSIAPDI
MSMEG_1204|M.smegmatis_MC2_155 ---------------------MVAKTTGN-GLPDVVVTAVASTTSLAPHA
TH_3445|M.thermoresistible__bu ---------------------MVSMRTGD-GFRNVVVTAVAATTPLAADA
*.. : ****.:* **.:*..
MMAR_3339|M.marinum_M ETTWKLLLDSQSGIRTLDDPFVEEFNLPVRIGGHLLEEFDHQLTRVELRR
MUL_1303|M.ulcerans_Agy99 ETTWKLLLDSQSGIRTLDDPFVEEFNLPVRIGGHLLEEFDHQLTRVELRR
Mb2270|M.bovis_AF2122/97 ETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIGGHLLEEFDHQLTRIELRR
Rv2246|M.tuberculosis_H37Rv ETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIGGHLLEEFDHQLTRIELRR
MLBr_01656|M.leprae_Br4923 ETTWKLLLDNQSGIRMLDDPFIEEFNLPVRIGGHLLEEFDHQLTRVELRR
MAV_2191|M.avium_104 ETTWKLLLDSQSGIRTLDDPFVEEFDLPVRIGGHLLEEFDSQLTRVELRR
Mflv_2776|M.gilvum_PYR-GCK EQTWTSLLDGRSGIRKLDDPFVEQFDLPVRIGGHLLEEFDAQLTKVENRR
Mvan_3757|M.vanbaalenii_PYR-1 EATWKSLLDGHSGIRKLQDPFVEEFDLPVQIGGHLLEEFDSQLTKVENRR
MAB_1877c|M.abscessus_ATCC_199 EGTWKGLIAGESGIEVLEDEFVEKFGLPVWIGGHLKEPIDNHMTRLELRR
MSMEG_1204|M.smegmatis_MC2_155 EDTWKLLLEGRSGIRALDKPFVEEFDSPVRIGGQLTEAFADKLGRVEQHR
TH_3445|M.thermoresistible__bu EGTWAGLLAGDSGIRPLDRPFVTDFDSPVRIGGRLVENFADQLSRVELRR
* ** *: ***. *: *: .*. ** ***:* * : :: ::* :*
MMAR_3339|M.marinum_M TAYLQRMSTVIGRRVWENAGSPE-VDTNRLAVSIGTGLGSAEELVFGYDE
MUL_1303|M.ulcerans_Agy99 TAYLQRMSTVIGRRVWENAGSPE-VDTNRLAVSIGTGLGSAEELVFGYDE
Mb2270|M.bovis_AF2122/97 MGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYDD
Rv2246|M.tuberculosis_H37Rv MGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYDD
MLBr_01656|M.leprae_Br4923 MGYLQRMSTVLSRRLWENAGSPE-VDTNRLMVSIGTGLGSAEELVFSYDD
MAV_2191|M.avium_104 TGYLQRMSTILGRRVWENAGSPE-VDSNRLMVSIGTGLGSSEEMVFSYDD
Mflv_2776|M.gilvum_PYR-GCK MSYIQKMATVLGRRVWENAGAPE-VDTERLLVSIGTGLGGAEALVFAYDG
Mvan_3757|M.vanbaalenii_PYR-1 MSYVQKMATVLGRRVWENAGSPE-VDTERLLVSIGTGLGGAEALVFAYDG
MAB_1877c|M.abscessus_ATCC_199 MAYVQRMALHVGRQVWQNAGSPDDIDKDRLGVVIGTGLGGGERIVETYDT
MSMEG_1204|M.smegmatis_MC2_155 LSYMGQMSTVLGRRLWETAGNPE-VDTRRLMVSIGMALGTTEELILQYDL
TH_3445|M.thermoresistible__bu LGFMQQMSTLLSRRLWETAGNPD-VDTKRLLVSIGLALGSTEEIPIQHNA
.:: :*: :.*::*:.** *: :*. ** * ** .** * : ::
MMAR_3339|M.marinum_M MRVRGFRAISPLAVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGSEAI
MUL_1303|M.ulcerans_Agy99 MRVRGFRAISPLAVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGSEAI
Mb2270|M.bovis_AF2122/97 MRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAI
Rv2246|M.tuberculosis_H37Rv MRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAI
MLBr_01656|M.leprae_Br4923 MRARGMKAVSPLAVQKYMPNGAAAAVGLEHHAKAGVMTPVSACASGSEAI
MAV_2191|M.avium_104 MRARGMKAVSPLGVQKYMPNGAAAAVGLEHHAKAGVITPVSACASGSEGI
Mflv_2776|M.gilvum_PYR-GCK LRERGLRSVSPLSVQMYMPNGPSAVVGLERHAKAGVVTPVSACASGSEGI
Mvan_3757|M.vanbaalenii_PYR-1 LRERGLRSVSPLSVQMYMPNGPSAVVGLERHAKAGVVTPVSACASGSEGI
MAB_1877c|M.abscessus_ATCC_199 MNEHGIRKVSPLAVQMCMPNGAAAVVGLEIGARAGVITPVSACSSGSEAI
MSMEG_1204|M.smegmatis_MC2_155 WKAKGLRAVPPTAIQKYMPNAPAAAVGLDRKAKAGIMSPIMADASGAAAI
TH_3445|M.thermoresistible__bu WKERGMRAISPLTVQMHMPNSAAAAVGLDRQAKAGVISPVMSDASGAAAI
. :*:: :.* :* ***..:*.***: *:**:::*: : :**: .*
MMAR_3339|M.marinum_M ARAWQQVVLGEADIAICGGVETRIEAVPIAGFANMRIVMSTNNDDPAGAC
MUL_1303|M.ulcerans_Agy99 ARAWQQVVLGEADIAICGGVETRIEAVPIAGFANMRIVMSTNNDDPAGAC
Mb2270|M.bovis_AF2122/97 ARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGAC
Rv2246|M.tuberculosis_H37Rv ARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGAC
MLBr_01656|M.leprae_Br4923 AHAWQQIVLGEADSAICGGVETKIEAVPIAGFSQMRIVMSTKNDNPAGAC
MAV_2191|M.avium_104 AQAWRNIVFGEADIAICGGVETKIEAVPIAAFAQMRIVMSTKNDDPVGAC
Mflv_2776|M.gilvum_PYR-GCK AQAWRNIVMGEADIAICGGVEQRIEAVPIAAFAQMRIVMSTNNDDPAGAC
Mvan_3757|M.vanbaalenii_PYR-1 AQAWRNIVLGEADIAICGGVEQRIEAVPIAGFAQMRIVMSANNDDPAGAC
MAB_1877c|M.abscessus_ATCC_199 AHAWRQIVMGDADMIVCGGVEGMIEALPIAAFSMMR-AMSTRNDEPEKAS
MSMEG_1204|M.smegmatis_MC2_155 AHAWREIILGDADIAICGGVETWIEAVPVGAFSQLG-MLSTYNDDPPAAC
TH_3445|M.thermoresistible__bu TEAWRHIVLGEADVAICGGVETVVEAVPVACFTQLG-MLSTHNDDPAAAC
:.**:.:::*:** :***** :**:*:. *: : :*: **:* *.
MMAR_3339|M.marinum_M RPFDKDRDGFVFGEGGALMVIETEEHAKARGANILARIMGASITSDGFHM
MUL_1303|M.ulcerans_Agy99 RPFDKDRDGFVFGEGGALMVIETEEHAKARGANILARIMGASITSDGFHM
Mb2270|M.bovis_AF2122/97 RPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHM
Rv2246|M.tuberculosis_H37Rv RPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHM
MLBr_01656|M.leprae_Br4923 RPFDRDRDGFVFGEAGALMLIETEDSAKARSANILARIMGASITSDGFHM
MAV_2191|M.avium_104 RPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYHM
Mflv_2776|M.gilvum_PYR-GCK RPFDKDRDGFVFGEAGALLVIETEEHAKARGATPLARLMGASITSDGFHM
Mvan_3757|M.vanbaalenii_PYR-1 RPFDKDRDGFVFGEAGALMVIETEEHARARGATPLARVMGASITSDGYHM
MAB_1877c|M.abscessus_ATCC_199 RPFDKDRDGFVFGEAGALMVIETEEHAKARGAQIIGRVMGAGITSDAYHM
MSMEG_1204|M.smegmatis_MC2_155 RPFDKDRDGMVLGEAGALMLVETEEHAKARGAPILARLMGAGMTNDCYDI
TH_3445|M.thermoresistible__bu RPFDQERDGMVFGEGGALLLIEAEEHAKARGATILARVMGGAITSDAYDP
****::* *:*:**.***:::*:*: *:**.* :.*:**..:*.* :.
MMAR_3339|M.marinum_M VAPDPNGERAGHAITRAVQLAGLQPSDIDHVNAHATGTQVGDVAEGRAIN
MUL_1303|M.ulcerans_Agy99 VAPDPNGERAGHAITRAVQLAGLQPSDIDHVNAHATGTQVGDVAEGRAIN
Mb2270|M.bovis_AF2122/97 VAPDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAIN
Rv2246|M.tuberculosis_H37Rv VAPDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAIN
MLBr_01656|M.leprae_Br4923 VAPDPNGERAGHAIARAVHLAGLSPSDIDHVNAHATGTQVGDLAEAKAIN
MAV_2191|M.avium_104 VAPDPNGERAGHAMSRAIQLAGLTPGDIDHVNAHATGTSVGDVAESKAIN
Mflv_2776|M.gilvum_PYR-GCK VAPDPDGERAGYAMTRAIELAGLTPTDIDHVNAHATGTSVGDVAEGRAIN
Mvan_3757|M.vanbaalenii_PYR-1 VAPDPNGERAGYAITRAIELAGLKPTDIDHVNAHATGTSVGDLAEGHAIN
MAB_1877c|M.abscessus_ATCC_199 VAPGPDGIRAGAAMTRAIQTAGLSPKDIDHINAHGTATPIGDVAEANAIH
MSMEG_1204|M.smegmatis_MC2_155 VKPDPDGQLAGDAIRRAIELAGLAPGDIDHINAHATGTDFGDLAEARAIH
TH_3445|M.thermoresistible__bu IDLEPGGECAAEAIGRAIYLAGLEPTDIDHVNAHAAGTRTGDLAEAHALQ
: *.* *. *: **: *** * ****:***.:.* **:**..*::
MMAR_3339|M.marinum_M NALGSH--KPAVYAPKSALGHSVGAVGAVESILTVLALRDQVVPPTLNLV
MUL_1303|M.ulcerans_Agy99 NALGSH--KPAVYAPKSALGHSVGAVGAVESILTVLALRDQVVPPTLNLV
Mb2270|M.bovis_AF2122/97 NALGGN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLV
Rv2246|M.tuberculosis_H37Rv NALGGN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLV
MLBr_01656|M.leprae_Br4923 KALCNN--RPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLV
MAV_2191|M.avium_104 NALGPHGGNAAVYAPKAALGHSVGAVGAVESILTVLALRDQVVPPTLNLE
Mflv_2776|M.gilvum_PYR-GCK RALGGH--RPAVYAPKSALGHSVGAVGAVESILTVQALRDGVVPPTLNLK
Mvan_3757|M.vanbaalenii_PYR-1 LAMGGH--RPAVYAPKSALGHSVGAVGAVESILTVQSLRDGIIPPTLNLK
MAB_1877c|M.abscessus_ATCC_199 VAGVQH---AAVYAPKSALGHSIGAVGALESVLTVLALRDGVIPPTLNLD
MSMEG_1204|M.smegmatis_MC2_155 NVLGSH--RPSVYASKAALGHSLGSAGAVEAVLTVQTLRDGIVPATLNVK
TH_3445|M.thermoresistible__bu RVFGAH--RPAVYAPKAALGNALGAAGAIEAVLTVQALRDGVVPPTLNLK
. : .:***.*:***:::*:.**:*::*** :*** ::*.***:
MMAR_3339|M.marinum_M NLDPEIDLDVVAGKPRPGNYRYAVNNSFGFGGHNVAITFGRY
MUL_1303|M.ulcerans_Agy99 NLDPEIDLDVVAGKPRPGNYRYAVNNSFGFGGHNVAITFGRY
Mb2270|M.bovis_AF2122/97 NLDPEIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY
Rv2246|M.tuberculosis_H37Rv NLDPEIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY
MLBr_01656|M.leprae_Br4923 NLDPDIDLDVVAGKPRPGDYRYAVNNSFGFGGHNVAIAFGCY
MAV_2191|M.avium_104 NLDPEIDLDVVAGKPRPGNYQYAINNSFGFGGHNVAIAFGRY
Mflv_2776|M.gilvum_PYR-GCK NQDPEIDLDVVAGSPRPGNYNYALNNSFGFGGHNVALAFGKY
Mvan_3757|M.vanbaalenii_PYR-1 NLDPEIDLDVVAGGPRPGNYEYAINNSFGFGGHNVALAFGKY
MAB_1877c|M.abscessus_ATCC_199 NLDPEIDLDVVAGEPRHGDFKYAINNSFGFGGHNVALAFGKY
MSMEG_1204|M.smegmatis_MC2_155 NPDPQIDLDVVTDQPRSEHYRYALSNSFGLGGNNVVLAFGAA
TH_3445|M.thermoresistible__bu NLDPEIDLDVVAGESRRGDYRYALTTSMGIGGHNVAVVFGAY
* **:******:. .* .:.**:..*:*:**:**.:.**