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M. thermoresistible (build 8) TH_3128 (-)

annotation: short chain dehydrogenase
coordinates: 970536 - 971282
length: 249

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3128 - - 100% (249) short chain dehydrogenase
M. thermoresistible (build 8) TH_1604 - 4e-44 41.49% (241) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8) TH_2552 - 3e-13 31.51% (219) PUTATIVE putative short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3820 - 5e-47 41.98% (243) short chain dehydrogenase
M. gilvum PYR-GCK Mflv_3100 - 1e-95 72.58% (248) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv2073c - 1e-101 75.71% (247) shortchain dehydrogenase
M. leprae Br4923 MLBr_00108 - 2e-48 41.56% (243) short chain dehydrogenase
M. abscessus ATCC 19977 MAB_2194 - 1e-88 68.05% (241) Probabme short-chain dehydrogenase/reductase
M. marinum M MMAR_3055 - 1e-102 76.33% (245) short chain dehydrogenase
M. avium 104 MAV_2423 - 1e-104 77.73% (247) short chain dehydrogenase
M. smegmatis MC2 155 MSMEG_3879 - 1e-107 78.57% (252) short chain dehydrogenase
M. ulcerans Agy99 MUL_2299 - 1e-101 75.51% (245) short chain dehydrogenase
M. vanbaalenii PYR-1 Mvan_3435 - 1e-96 72.69% (249) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


TH_3128|M.thermoresistible__bu      -MKDTGG----L-----------VVIFGGRSEIGAELAARLAPG--ATVL
MSMEG_3879|M.smegmatis_MC2_155      -MKDTADTDRRV-----------VVIFGGRSEIGTELAVRLAPG--NTVV
MMAR_3055|M.marinum_M               -MDDTSAGP--------------VVIFGGRSEIGGELARRLAPG--ATVI
MUL_2299|M.ulcerans_Agy99           -MDDTSAGP--------------VVIFGGRSEIGSELARRLAPG--ATVI
Rv2073c|M.tuberculosis_H37Rv        -MDDTGAAP--------------VVIFGGRSQIGGELARRLAAG--ATMV
MAV_2423|M.avium_104                -MDDTGAAP--------------VLILGGRSEIGVELARRLAPG--ATVV
Mflv_3100|M.gilvum_PYR-GCK          -MRDTNV----------------VVIFGGRSEIGSELAQRLARG--ATVV
Mvan_3435|M.vanbaalenii_PYR-1       -MKDTNAGP--------------VVIFGGRSEIGVEVARRLAPG--ATVV
MAB_2194|M.abscessus_ATCC_1997      -MTDTVRHSGQLGDKPLGRRPSTVVIFGGRSEIGLEVATRLAPD--NTVV
Mb3820|M.bovis_AF2122/97            MVLDAVGNPQ------------TVLLLGGTSEIGLAICERYLHNSAARIV
MLBr_00108|M.leprae_Br4923          MVLDAVGHPQ------------TVLLLGGTSEIGLAICKRYLRNAPARIV
                                     : *:                  *:::** *:**  :. *   .    ::

TH_3128|M.thermoresistible__bu      LAARRAD-RLDDQVAAVAAAGAAAVHTREFDADDLDSHAPLVSGIVDEFG
MSMEG_3879|M.smegmatis_MC2_155      LAARGAD-RLEPQVAAVRDAGAAAVHTCEFDADDIAAHAPVVEEIESAHG
MMAR_3055|M.marinum_M               LAARGAD-RLDVQVAALKTAGAAAVHTREFDADNVAGHGPLVASIVADHG
MUL_2299|M.ulcerans_Agy99           LAARGAD-QLDVQVAALKTAGAAAVHTREFDADDVAGHGPLVASIVADHG
Rv2073c|M.tuberculosis_H37Rv        LAARNAD-QLADQAAALRAAGAIAVHTREFDADDLAAHGPLVASLVAEHG
MAV_2423|M.avium_104                LAARDAD-RLNDKVDALKAAGASAVHTREFDADDLASHGPLVASVVADHG
Mflv_3100|M.gilvum_PYR-GCK          LAARRPD-DLAPQIEELRRAGAAAVHPVGFDADDLASHQPVVDAIIAEHG
Mvan_3435|M.vanbaalenii_PYR-1       LAARRPD-ELQGEVAELQRAGAVAVHTVGFDADDLASHRGVVDGIVAEHG
MAB_2194|M.abscessus_ATCC_1997      LAARRAD-DLREEKRRILEAGATGIDCVEFDAGRLDTHESVLDSIIERYG
Mb3820|M.bovis_AF2122/97            LACLPDDPRREDAAAAMKQAGARSVELIDFDALDTDSHPKMIEAAFSG-G
MLBr_00108|M.leprae_Br4923          LAAMPDDPNREDAVAQMTAVGARSVELIDFEALDTDSHPRMIEQAFTG-G
                                    **.   *         :  .** .:.   *:*     *  ::       *

TH_3128|M.thermoresistible__bu      PIDTAVLAFGILGDQARAESDPAHAVQIVHTDYVAQVSLLTVLADRMRAA
MSMEG_3879|M.smegmatis_MC2_155      PIDTAVLAFGVLGDQARAEDDAAHAVAVVHTDYVAQVGLLTELARRMRTA
MMAR_3055|M.marinum_M               PIGTAVLAFGILGDQARAERDAEHAIAIVHTDYVAQISLLTHLAAAMRSA
MUL_2299|M.ulcerans_Agy99           PIGTAVLAFGILGDQARAERDAEHAIAIVHTDYVAQISLLTHLAAAMRTA
Rv2073c|M.tuberculosis_H37Rv        PIGTAVLAFGILGDQARAETDAAHAVAIVHTDYVAQVSLLTHLAAAMRTA
MAV_2423|M.avium_104                PIGTAVLAYGILGDQARAETDAEHAVAIVHTDYVAQVSMLTHLATAMRAA
Mflv_3100|M.gilvum_PYR-GCK          PIGTAVLAFGILGDQARAETDAAHAAAIAHTDYVAQVSLLTVLAVRMREA
Mvan_3435|M.vanbaalenii_PYR-1       PIGIAVLAFGILGDQARAEKDPAHAAAIAHTDYVAQVSLLTVLAASMRDA
MAB_2194|M.abscessus_ATCC_1997      AIDVAVLAFGLLGDQARAETDSEHAAAIVHIDYVAQIALLTSLAVRMRGV
Mb3820|M.bovis_AF2122/97            DVDVAIVAFGLLGDAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQ
MLBr_00108|M.leprae_Br4923          DVDVAIVAFGLLGDAEELWQNQSKAVQIAEINYTAAVSVGVLLGEKMRAQ
                                     :. *::*:*:***  .   :  :*  :.. :*.* :.: . *.  **  

TH_3128|M.thermoresistible__bu      GRGRLVVFSSIAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVHLLI
MSMEG_3879|M.smegmatis_MC2_155      GHGRLVVFSSIAGARVRRANYVYGSAKAGLDGFACGLSDALHGTGVHVLI
MMAR_3055|M.marinum_M               GRGALVVFSSVAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVRLLI
MUL_2299|M.ulcerans_Agy99           GRGALVVFSSVAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVRLLI
Rv2073c|M.tuberculosis_H37Rv        GRGSLVVFSSVAGIRVRRANYVYGSAKAGLDGFASGLADALHGTGVRLLI
MAV_2423|M.avium_104                GRGQLVVFSSIAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVRLLI
Mflv_3100|M.gilvum_PYR-GCK          GSGRLVVFSSIAGHRVRRANYVYGSAKAGLDGFCSGLADALHGSGVHLLL
Mvan_3435|M.vanbaalenii_PYR-1       GSGTLVVFSSVAGVRVRRANYVYGSAKAGLDGFSSGLADALHGTGVRLLL
MAB_2194|M.abscessus_ATCC_1997      GRGALVVFSSIAGWRVRRANYVYGSAKAGLDGFASGLADALHGSGVRLLI
Mb3820|M.bovis_AF2122/97            GFGQIIAMSSAAGERVRRANFVYGSTKAGLDGFYLGLSEALREYGVRVLV
MLBr_00108|M.leprae_Br4923          GFGQIIVMSSAAGERVRRSNFVYGSTKAGLDGFYLGLSEALHEYGVHVLV
                                    * * ::.:** ** ****:*:****:*******  **::**:  **::*:

TH_3128|M.thermoresistible__bu      VRPGFVIGRMTEGMDPAPFASTPAQVANAAARALARGRRAVWVPRVIGPL
MSMEG_3879|M.smegmatis_MC2_155      VRPGFVIGHMTEGMEPAPFASTPAQVADAAAKALARGKRAVWVPWVIRPM
MMAR_3055|M.marinum_M               VRPGFVIGRMTEGMAPAPLSSTPDQVAAATTRALAKGRRTVWIPWALRPM
MUL_2299|M.ulcerans_Agy99           LRPGFVIGRMTEGMAPAPLSCTPDQVAAATTRALAKGRRTVWIPWALRPM
Rv2073c|M.tuberculosis_H37Rv        ARPGFVIGRMTEGMTPAPLSVTPERVAAATARALVNGKRVVWIPWALRPM
MAV_2423|M.avium_104                VRPGFVIGRMTEGMTPAPLSSTPAQVAAATARALAKGRRTVWIPWALGPA
Mflv_3100|M.gilvum_PYR-GCK          VRPGFVIGRMTEGMSPAPLSSTPAQVADATVTALNRGRDTVWIPAPLAVL
Mvan_3435|M.vanbaalenii_PYR-1       VRPGFVVGRMTQGMSPAPLSSTPGQVAEATVRALRKGRGTVWIPAPLVLL
MAB_2194|M.abscessus_ATCC_1997      ARPGFVIGRMSAGMSPAPLSSTPPQVAAATVRALRGGKRTVWIPRPLGAL
Mb3820|M.bovis_AF2122/97            IRPGQVRTRMSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYV
MLBr_00108|M.leprae_Br4923          IRPGQVRTRMSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYV
                                     *** *  :*:  :  **::     **  :. *   *:  ** *  :   

TH_3128|M.thermoresistible__bu      AVTMRFVPRFVWRRMPR
MSMEG_3879|M.smegmatis_MC2_155      AFTTRFVPQVLWRRMPR
MMAR_3055|M.marinum_M               FFVLRLLPQFVWRKMPR
MUL_2299|M.ulcerans_Agy99           FFVLRPLPQFVWRKMPR
Rv2073c|M.tuberculosis_H37Rv        FVALRLLPRFVWRRMPR
MAV_2423|M.avium_104                AAVLRMLPQPIWRRMPR
Mflv_3100|M.gilvum_PYR-GCK          ATALRLMPRWAWRRVKR
Mvan_3435|M.vanbaalenii_PYR-1       AFAFRTMPRFVWRRLPR
MAB_2194|M.abscessus_ATCC_1997      AFVMRWVPSSVWRRMPR
Mb3820|M.bovis_AF2122/97            MMVLRHIPRSIFRKLPI
MLBr_00108|M.leprae_Br4923          MMVLRHIPRSIFRKLPI
                                      . * :*   :*::

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3128	-	-	100% (249)	short chain dehydrogenase
M. thermoresistible (build 8)	TH_1604	-	4e-44	41.49% (241)	PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8)	TH_2552	-	3e-13	31.51% (219)	PUTATIVE putative short-chain dehydrogenase/reductase SDR