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VRDTNVVVIFGGRSEIGSELAQRLARGATVVLAARRPDDLAPQIEELRRAGAAAVHPVGFDADDLASHQP VVDAIIAEHGPIGTAVLAFGILGDQARAETDAAHAAAIAHTDYVAQVSLLTVLAVRMREAGSGRLVVFSS IAGHRVRRANYVYGSAKAGLDGFCSGLADALHGSGVHLLLVRPGFVIGRMTEGMSPAPLSSTPAQVADAT VTALNRGRDTVWIPAPLAVLATALRLMPRWAWRRVKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3100 | - | - | 100% (247) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1177 | - | 7e-41 | 39.52% (248) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1569 | - | 6e-11 | 30.73% (218) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3820 | - | 2e-43 | 40.40% (250) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2073c | - | 4e-95 | 73.86% (241) | shortchain dehydrogenase |
| M. leprae Br4923 | MLBr_00108 | - | 1e-44 | 40.08% (242) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2194 | - | 8e-87 | 67.89% (246) | Probabme short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_3055 | - | 9e-94 | 71.49% (249) | short chain dehydrogenase |
| M. avium 104 | MAV_2423 | - | 6e-95 | 73.44% (241) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3879 | - | 3e-93 | 70.61% (245) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3128 | - | 8e-96 | 72.58% (248) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_2299 | - | 2e-93 | 71.08% (249) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3435 | - | 1e-108 | 79.92% (249) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3100|M.gilvum_PYR-GCK -MRDTNV----------------VVIFGGRSEIGSELAQRLARG--ATVV
Mvan_3435|M.vanbaalenii_PYR-1 -MKDTNAGP--------------VVIFGGRSEIGVEVARRLAPG--ATVV
MMAR_3055|M.marinum_M -MDDTSAGP--------------VVIFGGRSEIGGELARRLAPG--ATVI
MUL_2299|M.ulcerans_Agy99 -MDDTSAGP--------------VVIFGGRSEIGSELARRLAPG--ATVI
Rv2073c|M.tuberculosis_H37Rv -MDDTGAAP--------------VVIFGGRSQIGGELARRLAAG--ATMV
MAV_2423|M.avium_104 -MDDTGAAP--------------VLILGGRSEIGVELARRLAPG--ATVV
MSMEG_3879|M.smegmatis_MC2_155 -MKDTADTDRRV-----------VVIFGGRSEIGTELAVRLAPG--NTVV
TH_3128|M.thermoresistible__bu -MKDTGG----L-----------VVIFGGRSEIGAELAARLAPG--ATVL
MAB_2194|M.abscessus_ATCC_1997 -MTDTVRHSGQLGDKPLGRRPSTVVIFGGRSEIGLEVATRLAPD--NTVV
Mb3820|M.bovis_AF2122/97 MVLDAVGNPQ------------TVLLLGGTSEIGLAICERYLHNSAARIV
MLBr_00108|M.leprae_Br4923 MVLDAVGHPQ------------TVLLLGGTSEIGLAICKRYLRNAPARIV
: *: *:::** *:** :. * . ::
Mflv_3100|M.gilvum_PYR-GCK LAARRPD-DLAPQIEELRRAGAAAVHPVGFDADDLASHQPVVDAIIAEHG
Mvan_3435|M.vanbaalenii_PYR-1 LAARRPD-ELQGEVAELQRAGAVAVHTVGFDADDLASHRGVVDGIVAEHG
MMAR_3055|M.marinum_M LAARGAD-RLDVQVAALKTAGAAAVHTREFDADNVAGHGPLVASIVADHG
MUL_2299|M.ulcerans_Agy99 LAARGAD-QLDVQVAALKTAGAAAVHTREFDADDVAGHGPLVASIVADHG
Rv2073c|M.tuberculosis_H37Rv LAARNAD-QLADQAAALRAAGAIAVHTREFDADDLAAHGPLVASLVAEHG
MAV_2423|M.avium_104 LAARDAD-RLNDKVDALKAAGASAVHTREFDADDLASHGPLVASVVADHG
MSMEG_3879|M.smegmatis_MC2_155 LAARGAD-RLEPQVAAVRDAGAAAVHTCEFDADDIAAHAPVVEEIESAHG
TH_3128|M.thermoresistible__bu LAARRAD-RLDDQVAAVAAAGAAAVHTREFDADDLDSHAPLVSGIVDEFG
MAB_2194|M.abscessus_ATCC_1997 LAARRAD-DLREEKRRILEAGATGIDCVEFDAGRLDTHESVLDSIIERYG
Mb3820|M.bovis_AF2122/97 LACLPDDPRREDAAAAMKQAGARSVELIDFDALDTDSHPKMIEAAFSG-G
MLBr_00108|M.leprae_Br4923 LAAMPDDPNREDAVAQMTAVGARSVELIDFEALDTDSHPRMIEQAFTG-G
**. * : .** .:. *:* * :: *
Mflv_3100|M.gilvum_PYR-GCK PIGTAVLAFGILGDQARAETDAAHAAAIAHTDYVAQVSLLTVLAVRMREA
Mvan_3435|M.vanbaalenii_PYR-1 PIGIAVLAFGILGDQARAEKDPAHAAAIAHTDYVAQVSLLTVLAASMRDA
MMAR_3055|M.marinum_M PIGTAVLAFGILGDQARAERDAEHAIAIVHTDYVAQISLLTHLAAAMRSA
MUL_2299|M.ulcerans_Agy99 PIGTAVLAFGILGDQARAERDAEHAIAIVHTDYVAQISLLTHLAAAMRTA
Rv2073c|M.tuberculosis_H37Rv PIGTAVLAFGILGDQARAETDAAHAVAIVHTDYVAQVSLLTHLAAAMRTA
MAV_2423|M.avium_104 PIGTAVLAYGILGDQARAETDAEHAVAIVHTDYVAQVSMLTHLATAMRAA
MSMEG_3879|M.smegmatis_MC2_155 PIDTAVLAFGVLGDQARAEDDAAHAVAVVHTDYVAQVGLLTELARRMRTA
TH_3128|M.thermoresistible__bu PIDTAVLAFGILGDQARAESDPAHAVQIVHTDYVAQVSLLTVLADRMRAA
MAB_2194|M.abscessus_ATCC_1997 AIDVAVLAFGLLGDQARAETDSEHAAAIVHIDYVAQIALLTSLAVRMRGV
Mb3820|M.bovis_AF2122/97 DVDVAIVAFGLLGDAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQ
MLBr_00108|M.leprae_Br4923 DVDVAIVAFGLLGDAEELWQNQSKAVQIAEINYTAAVSVGVLLGEKMRAQ
:. *::*:*:*** . : :* :.. :*.* :.: . *. **
Mflv_3100|M.gilvum_PYR-GCK GSGRLVVFSSIAGHRVRRANYVYGSAKAGLDGFCSGLADALHGSGVHLLL
Mvan_3435|M.vanbaalenii_PYR-1 GSGTLVVFSSVAGVRVRRANYVYGSAKAGLDGFSSGLADALHGTGVRLLL
MMAR_3055|M.marinum_M GRGALVVFSSVAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVRLLI
MUL_2299|M.ulcerans_Agy99 GRGALVVFSSVAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVRLLI
Rv2073c|M.tuberculosis_H37Rv GRGSLVVFSSVAGIRVRRANYVYGSAKAGLDGFASGLADALHGTGVRLLI
MAV_2423|M.avium_104 GRGQLVVFSSIAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVRLLI
MSMEG_3879|M.smegmatis_MC2_155 GHGRLVVFSSIAGARVRRANYVYGSAKAGLDGFACGLSDALHGTGVHVLI
TH_3128|M.thermoresistible__bu GRGRLVVFSSIAGARVRRANYVYGSAKAGLDGFASGLADALHGTGVHLLI
MAB_2194|M.abscessus_ATCC_1997 GRGALVVFSSIAGWRVRRANYVYGSAKAGLDGFASGLADALHGSGVRLLI
Mb3820|M.bovis_AF2122/97 GFGQIIAMSSAAGERVRRANFVYGSTKAGLDGFYLGLSEALREYGVRVLV
MLBr_00108|M.leprae_Br4923 GFGQIIVMSSAAGERVRRSNFVYGSTKAGLDGFYLGLSEALHEYGVHVLV
* * ::.:** ** ****:*:****:******* **::**: **::*:
Mflv_3100|M.gilvum_PYR-GCK VRPGFVIGRMTEGMSPAPLSSTPAQVADATVTALNRGRDTVWIPAPLAVL
Mvan_3435|M.vanbaalenii_PYR-1 VRPGFVVGRMTQGMSPAPLSSTPGQVAEATVRALRKGRGTVWIPAPLVLL
MMAR_3055|M.marinum_M VRPGFVIGRMTEGMAPAPLSSTPDQVAAATTRALAKGRRTVWIPWALRPM
MUL_2299|M.ulcerans_Agy99 LRPGFVIGRMTEGMAPAPLSCTPDQVAAATTRALAKGRRTVWIPWALRPM
Rv2073c|M.tuberculosis_H37Rv ARPGFVIGRMTEGMTPAPLSVTPERVAAATARALVNGKRVVWIPWALRPM
MAV_2423|M.avium_104 VRPGFVIGRMTEGMTPAPLSSTPAQVAAATARALAKGRRTVWIPWALGPA
MSMEG_3879|M.smegmatis_MC2_155 VRPGFVIGHMTEGMEPAPFASTPAQVADAAAKALARGKRAVWVPWVIRPM
TH_3128|M.thermoresistible__bu VRPGFVIGRMTEGMDPAPFASTPAQVANAAARALARGRRAVWVPRVIGPL
MAB_2194|M.abscessus_ATCC_1997 ARPGFVIGRMSAGMSPAPLSSTPPQVAAATVRALRGGKRTVWIPRPLGAL
Mb3820|M.bovis_AF2122/97 IRPGQVRTRMSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYV
MLBr_00108|M.leprae_Br4923 IRPGQVRTRMSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYV
*** * :*: : **:: ** :. * *: ** * :
Mflv_3100|M.gilvum_PYR-GCK ATALRLMPRWAWRRVKR
Mvan_3435|M.vanbaalenii_PYR-1 AFAFRTMPRFVWRRLPR
MMAR_3055|M.marinum_M FFVLRLLPQFVWRKMPR
MUL_2299|M.ulcerans_Agy99 FFVLRPLPQFVWRKMPR
Rv2073c|M.tuberculosis_H37Rv FVALRLLPRFVWRRMPR
MAV_2423|M.avium_104 AAVLRMLPQPIWRRMPR
MSMEG_3879|M.smegmatis_MC2_155 AFTTRFVPQVLWRRMPR
TH_3128|M.thermoresistible__bu AVTMRFVPRFVWRRMPR
MAB_2194|M.abscessus_ATCC_1997 AFVMRWVPSSVWRRMPR
Mb3820|M.bovis_AF2122/97 MMVLRHIPRSIFRKLPI
MLBr_00108|M.leprae_Br4923 MMVLRHIPRSIFRKLPI
. * :* :*::