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M. thermoresistible (build 8) TH_3020 (-)

annotation: virulence factor Mce family protein
coordinates: 2705764 - 2707239
length: 492

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3020--100% (492)virulence factor Mce family protein
M. thermoresistible (build 8)TH_4233-e-17365.00% (440) PUTATIVE virulence factor mce family protein
M. thermoresistible (build 8)TH_3797-4e-8239.85% (399) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0178mce1D0.068.18% (440) MCE-family protein MCE1D
M. gilvum PYR-GCKMflv_0708-0.074.32% (440) virulence factor Mce family protein
M. tuberculosis H37RvRv0172mce1D0.068.18% (440) MCE-family protein MCE1D
M. leprae Br4923MLBr_02592mce1D1e-17667.73% (440) putative secreted protein
M. abscessus ATCC 19977MAB_4150c-3e-5932.82% (387) MCE-family protein
M. marinum MMMAR_0415mce1D1e-18068.86% (440) MCE-family protein Mce1D
M. avium 104MAV_5012-0.070.91% (440) mce-family protein mce1d
M. smegmatis MC2 155MSMEG_0137-0.073.81% (443) virulence factor mce family protein
M. ulcerans Agy99MUL_1065mce1D1e-18068.64% (440) MCE-family protein Mce1D
M. vanbaalenii PYR-1Mvan_0137-0.074.55% (440) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0708|M.gilvum_PYR-GCK          MSTIFNVRNMKGPGLSRG-LIIGAVVLVLVVVGAFLGMKLYKQMTTKTVV
Mvan_0137|M.vanbaalenii_PYR-1       MSTVFNVRNLKSPGASRATLIIGVIVVVLAVVGAVLGWNLYKQMTTKTVV
MSMEG_0137|M.smegmatis_MC2_155      MSTIFNIRNIQLPRLSRAAVIIGALVVAAALVAGYFGMNAYRKLTNTTVT
TH_3020|M.thermoresistible__bu      MSTIFNVRNLRLPRLSRTAVILGALVVALALVAAVVGYQLYKRITTNTAV
MMAR_0415|M.marinum_M               MSTIFDIRNIRLPKVSRATVIIGSLVLVLGLVAAFVGLKLYQKLTNNTVV
MUL_1065|M.ulcerans_Agy99           MSTIFDIRNIRLPEVSRATVIIGSLVLVLGLVAAFVGLKLYQKLTNNTVV
MAV_5012|M.avium_104                MSTIFDIRNIRLPKLSRTSVILGALVIVLALVVGYVGWRLYEKLTNNTVV
MLBr_02592|M.leprae_Br4923          MSTIFDVRKLKLLRLSRAPVIVGSLVVVLALVVGFVGWRLYQKLTNNTVV
Mb0178|M.bovis_AF2122/97            MSTIFDIRNLRLPQLSRASVVIGSLVVVLALAAGIVGVRLYQKLTNNTVV
Rv0172|M.tuberculosis_H37Rv         MSTIFDIRNLRLPQLSRASVVIGSLVVVLALAAGIVGVRLYQKLTNNTVV
MAB_4150c|M.abscessus_ATCC_199      ------------MTTSKTWLKRGAFAMLSVALVGGLLYWVWPSRGTYKIV
                                                   *:  :  * ..:      . .    :    . . .

Mflv_0708|M.gilvum_PYR-GCK          AYFTQTLAIYPGDKVQIMGVQVGAIDKIEPAGDKMKVTFHYEDKYRVPEN
Mvan_0137|M.vanbaalenii_PYR-1       AYFTQTLAIYPGDKVQIMGVQVGSIDKIEPAGDKMKVTFHYAGKYKVPQD
MSMEG_0137|M.smegmatis_MC2_155      AYFPEVLALYPGDKVLIMGVRVGSIDSIETAGDKMKVVFHFNNKYKVPEN
TH_3020|M.thermoresistible__bu      AYFEQTLALYPGDKVQIMGVHVGNIDTIEPAGDKMKVTFHYDSKYKLPSD
MMAR_0415|M.marinum_M               AYFPSANALYPGDKVQIMGLQVGKIDNIEPAGDKMKVTFHYQNKYKVPAN
MUL_1065|M.ulcerans_Agy99           AYFPSANALYPGDKVQIMGLQVGKIDNIEPAGDKMKVTFHYQNKYKVPAN
MAV_5012|M.avium_104                AYFPAANALYPGDKVQIMGLRVGAIDKIEPSGDKMKVTFHYQNKYRVPAN
MLBr_02592|M.leprae_Br4923          VYFPAATALYTGDKVQIMGLRVGSIDSIVPAGDKMKVTFHYQNKYKVPAN
Mb0178|M.bovis_AF2122/97            AYFTQANALYVGDKVQIMGLPVGSIDKIEPAGDKMKVTFHYQNKYKVPAN
Rv0172|M.tuberculosis_H37Rv         AYFTQANALYVGDKVQIMGLPVGSIDKIEPAGDKMKVTFHYQNKYKVPAN
MAB_4150c|M.abscessus_ATCC_199      GHFASAVGLYPGDDVRILGVKAGRISAVEPREGDVKVTMEMPDKFKVPEG
                                     :*  . .:* **.* *:*: .* *. : .  ..:**.:.  .*:::* .

Mflv_0708|M.gilvum_PYR-GCK          ATASILNPSLVASRTIQLSPAYTGGNTLPDNAVLDIDRTQVPVEYDDLRD
Mvan_0137|M.vanbaalenii_PYR-1       ATASILNPSLVASRTIQLSPPYTGGPVLADGAVLDVDRTQVPVEYDDVRD
MSMEG_0137|M.smegmatis_MC2_155      ATASILNPSLVASRVIQLSPPYTGGPTLRDGAVLDVDRTQVPIEYDEVRN
TH_3020|M.thermoresistible__bu      VSASILNPSLVASRSIQLSPPYTGGDTFPDGGVIPIERTQVPVEWDELRN
MMAR_0415|M.marinum_M               ASAVILNPTLVASRTIQLEPPYKGGPVLADNAVIPLERTQVPVEWDELRN
MUL_1065|M.ulcerans_Agy99           ASAVILNPTLVASRTIQLEPPYKGGPVLADNAVIPLERTQVPVEWDELRN
MAV_5012|M.avium_104                ASAVILNPTLVASRAIQLEPPYKGGPVLADNAVIPEERTQVPVEWDQLRN
MLBr_02592|M.leprae_Br4923          ASAVILNPTLVASRSIQLEPPYKGGPALGDNAVIPLERTQVPVEWDELRD
Mb0178|M.bovis_AF2122/97            ASAVILNPTLVASRNIQLEPPYRGGPVLADNAVIPVERTQVPTEWDELRD
Rv0172|M.tuberculosis_H37Rv         ASAVILNPTLVASRNIQLEPPYRGGPVLADNAVIPVERTQVPTEWDELRD
MAB_4150c|M.abscessus_ATCC_199      AQAIIMAPNLVTARFVQLTPAYTDGKALQDGASLGLDKTAVPIEWDEVKT
                                    . * *: *.**::* :** *.* .* .: *.. :  ::* ** *:*::: 

Mflv_0708|M.gilvum_PYR-GCK          SISRLLTDLGPTPEQPKGPFGDIIESAADGFAGKGKQLNSTLNNLSEALF
Mvan_0137|M.vanbaalenii_PYR-1       SISRLLTDLGPTPEQPKGPFGDIIESAADGFAGKGEQLNKTLNNLSEALF
MSMEG_0137|M.smegmatis_MC2_155      QVTRLLADLGPTPEQPKGPFGDIIESFADGFAGKGEQLNRTLRGLSDALT
TH_3020|M.thermoresistible__bu      SIDRILTDLGPTDEQPMGPFGDVVDSFADGLAGKGQQINQTLTSLSEALT
MMAR_0415|M.marinum_M               SITNIIDKLGPTKDQPTGPFGEVLESFANGLEGKGKQINTTLDSLSRALT
MUL_1065|M.ulcerans_Agy99           SITNIIDKLGPTKDQPTGPFGEVLESFANGLEGKGKQINTTLDSLSRALI
MAV_5012|M.avium_104                SITNIISKLGPTAEQPKGPFGEVIESFADGLAGKGKQFNTTLTNLSRALT
MLBr_02592|M.leprae_Br4923          SITKIISKLGPTKEQPKGPFGDVIESFADGLAGKGKQINATLDSLSRALT
Mb0178|M.bovis_AF2122/97            SVSHIIDELGPTPEQPKGPFGEVIEAFADGLAGKGKQINTTLNSLSQALN
Rv0172|M.tuberculosis_H37Rv         SVSHIIDELGPTPEQPKGPFGEVIEAFADGLAGKGKQINTTLNSLSQALN
MAB_4150c|M.abscessus_ATCC_199      ELAKLSDSLGPQ-GQSKGPVSDFINQAATTFDGNGDSFRNAVRELSQAAG
                                    .: .:  .***   *. **..:.::  *  : *:*..:. ::  ** *  

Mflv_0708|M.gilvum_PYR-GCK          ALNEGRGDFFSVVKSLATFVNALHQSDQQFVALNNDLAQFTNAFTDSDRE
Mvan_0137|M.vanbaalenii_PYR-1       ALNEGRGDFFSVVKSLALFVNALHQSDQQFVALNNNLAQFTNAFTDTDRE
MSMEG_0137|M.smegmatis_MC2_155      ALNEGRGDFFAVVKSLALFVNALHRSDQQFVALNNDLAQFTNSFTNTDQE
TH_3020|M.thermoresistible__bu      ALNEGRGDFFGVVKSLALFVNALHRSDQQFVALNRDLAQFTTSFANTDQE
MMAR_0415|M.marinum_M               ALNEGRGDFFAVVRSLALFVNALHQDDKQFVALNQNLADVTGRLVGYDRD
MUL_1065|M.ulcerans_Agy99           ALNEGRGDFFAVVRSLALFVNALHQDDKQFVALNQNLADVTGRLVGYDRD
MAV_5012|M.avium_104                ALNEGRGDFFAVVRSLALFVNALHQDDQQFVALNQNLADFTTRLAHSDGD
MLBr_02592|M.leprae_Br4923          ALNEGRGDFFAVLRSLALFVNALHTDDQQFVALNQNLADFTTRLAHSDTD
Mb0178|M.bovis_AF2122/97            ALNEGRGDFFAVVRSLALFVNALHQDDQQFVALNKNLAEFTDRLTHSDAD
Rv0172|M.tuberculosis_H37Rv         ALNEGRGDFFAVVRSLALFVNALHQDDQQFVALNKNLAEFTDRLTHSDAD
MAB_4150c|M.abscessus_ATCC_199      RLGDSRTDLFGTIKNLQTLVDALANSNEQIVQFSTHLASVSKVLAASTEN
                                     *.:.* *:*..::.*  :*:**  .::*:* :. .**..:  :.    :

Mflv_0708|M.gilvum_PYR-GCK          VANALQDLDELLTTTRGFIDENGEVLAHDVQNLAEVTNAILQPEPLDGLE
Mvan_0137|M.vanbaalenii_PYR-1       VADALRDLNELLTTTRNFVDENGEVLAHDVQNLADVTNAILQPEPRDGLE
MSMEG_0137|M.smegmatis_MC2_155      LANALQDLNRVLKTTREFLDRNGGVLTHDIDNLEQVTTAILQPEPRDGLE
TH_3020|M.thermoresistible__bu      LANAVRDLDELLTTTRQFLDENAEVLTYDINNLAEVTNAILQPEPLDGLE
MMAR_0415|M.marinum_M               LSNALQQFDSLLSTVRPFLDKNREVLTYDVNNLAEATNTLLQPDPLNGLE
MUL_1065|M.ulcerans_Agy99           LSNALQQFDSLLSTVRPFLDKNREVLTYDVNNLAEATNTLLQPDPLNGLE
MAV_5012|M.avium_104                LANAIEQFDSLLTTVRPWLDKNRGVLTYDVKNLETATNALLQPDPLNGLE
MLBr_02592|M.leprae_Br4923          LSSALQQFNSMLSTVQSFLVKNREVLAADVNNLATVNNTVVQPEPLNGVE
Mb0178|M.bovis_AF2122/97            LSNAIQQFDSLLAVARPFFAKNREVLTHDVNNLATVTTTLLQPDPLDGLE
Rv0172|M.tuberculosis_H37Rv         LSNAIQQFDSLLAVARPFFAKNREVLTHDVNNLATVTTTLLQPDPLDGLE
MAB_4150c|M.abscessus_ATCC_199      LGATLGALNQALTDVRGFLGDTNSALIDQVNKLSDFVKIFS--DQSDDLE
                                    :. ::  ::  *  .: :.  .  .*  ::.:*    . .   :  :.:*

Mflv_0708|M.gilvum_PYR-GCK          TALHAYPNVAANLMNISSPNAGGIVTMPVIS---NFANPMQFLCS-AIQA
Mvan_0137|M.vanbaalenii_PYR-1       TALHAYPNVAANLMNISSPNAGGIVTMPVIS---NFANPMQFLCS-AIQA
MSMEG_0137|M.smegmatis_MC2_155      TGLHAYPNLAANVLNINSPNQGGIIGLPVLPGVTNFSNPLQFVCS-SIQA
TH_3020|M.thermoresistible__bu      TALHVFPTMGANIMNISSPNSGGIVSLPVVT---NFANPLQFICS-AIQA
MMAR_0415|M.marinum_M               TALHVLPTAASNVNQIYHPAHGSVVAVPEIT---SFANPMQFVCS-SIQA
MUL_1065|M.ulcerans_Agy99           TALHVLPTAASNVNHIYHPAHGSVVAVPEIT---SFANPMQFVCS-SIQA
MAV_5012|M.avium_104                TALHVLPTAAANINQIYHPSHGSVVAIPSIT---NFANPMQFICS-AIQA
MLBr_02592|M.leprae_Br4923          TFLHVAPTAAANMNQLYHPAHGSVVGVPTIT---NFANPMQFICS-AIQA
Mb0178|M.bovis_AF2122/97            TVLHIFPTLAANINQLYHPTHGGVVSLSAFT---NFANPMEFICS-SIQA
Rv0172|M.tuberculosis_H37Rv         TVLHIFPTLAANINQLYHPTHGGVVSLSAFT---NFANPMEFICS-SIQA
MAB_4150c|M.abscessus_ATCC_199      QILHVAPNGLANFYNIYNPAAGTLNGMLSIP---NLANPVQFICGGVFET
                                      **  *.  :*. ::  *  * :  :  ..   .::**::*:*.  :::

Mflv_0708|M.gilvum_PYR-GCK          GSRLGYQESAELCAQYLGPILDAIKFNYLPFGANQLQTAMTLPKQISYSE
Mvan_0137|M.vanbaalenii_PYR-1       GSRLGYQESAELCAQYLGPILDAIKFNYLPFGANQLQTAMTLPKQIAYSE
MSMEG_0137|M.smegmatis_MC2_155      GSRLGYQESAELCAQYLAPIMDAIKFNYLPFGMNLASTAMTLPKQIAYSE
TH_3020|M.thermoresistible__bu      GSRLGYQESAELCAEYLAPILDAIKFNFPPFGFNQITTASVLPKQVAYSE
MMAR_0415|M.marinum_M               GSRLGYQESAELCAQYLAPVLDAIKFNYFPFGLNAFNTAEVLPKQVAYSE
MUL_1065|M.ulcerans_Agy99           GSRLGYQESAELCAQYLAPVLDAIKFNYFPFGLNAFNTAEVLPKQVAYSE
MAV_5012|M.avium_104                GSRLGYQESAELCAQYLAPILDAIKFNYPPFGLNLFSTAETLPKEVAYSE
MLBr_02592|M.leprae_Br4923          GSRLGYQESAELCAQYLSPVLDAIKFNYFPFGLNLFSTAEVLPKEVAYSE
Mb0178|M.bovis_AF2122/97            GSRLGYQESAELCAQYLAPVLDAIKFNYFPFGLNVASTASTLPKEIAYSE
Rv0172|M.tuberculosis_H37Rv         GSRLGYQESAELCAQYLAPVLDAIKFNYFPFGLNVASTASTLPKEIAYSE
MAB_4150c|M.abscessus_ATCC_199      GTKTEYLKRAEICRERMGPVLRRATFNYAPILLHPINQISAYKGQIIYDT
                                    *::  * : **:* : :.*::   .**: *:  :      .   :: *. 

Mflv_0708|M.gilvum_PYR-GCK          ERLRPPPGYKDTTVPGIFSRDTLFSHGNHEPAWVVAPGMQGVEVQPFTRN
Mvan_0137|M.vanbaalenii_PYR-1       ERLRPPPGYKDTTVPGIFSRDTLFSHGNHEPGWVVAPGMQGVEVQPFTQN
MSMEG_0137|M.smegmatis_MC2_155      KRLQPPPGYKDTTVPGIWSRDTLFSHGNHEPGWIVAPGMQGVQVQPATAN
TH_3020|M.thermoresistible__bu      PRLQPPPGYKDTTVPGIWSRDTLFSHGNHEPGWIVAPGMQGIQVX-----
MMAR_0415|M.marinum_M               PRLQPPNGYKDTTVPGIWVPDTPLSHRNTQPGWIVAPGMQGQQVGPITAG
MUL_1065|M.ulcerans_Agy99           PRLQPPNGYKDTTVPGIWVPDTPLSHRNTQPGWIVAPGMQGQQVGPITAG
MAV_5012|M.avium_104                PRLQPPNGYKDTTVPGIWVPDTPTSHRNTQPGWIVAPGMQGQQVGPITAG
MLBr_02592|M.leprae_Br4923          ARLQPPSGYKDTTVPGIWVPDTPLSHRNTQPGWIVAPGMQGQQVGPITAA
Mb0178|M.bovis_AF2122/97            PRLQPPNGYKDTTVPGIWVPDTPLSHRNTQPGWVVAPGMQGVQVGPITQG
Rv0172|M.tuberculosis_H37Rv         PRLQPPNGYKDTTVPGIWVPDTPLSHRNTQPGWVVAPGMQGVQVGPITQG
MAB_4150c|M.abscessus_ATCC_199      PETEAKSQAPREDLVWVRPNGAPPPPK-----------------------
                                     . ..        :  :   .:  .                         

Mflv_0708|M.gilvum_PYR-GCK          MLTPESLSELMGGPDVAPPPAPPAFGTTRNGNLPGPPNAFDQNNPLPPP-
Mvan_0137|M.vanbaalenii_PYR-1       MLTPESLAELMGGPDIVPPPAPPAFGTTRNGNLPGPPNAFDQNNPLPPP-
MSMEG_0137|M.smegmatis_MC2_155      MLTPESLAELLGGPDIVPPPAPPAFGTTRGGNLPGPPNAFDENNPLPPP-
TH_3020|M.thermoresistible__bu      ------------------XXAWDACRSTGSTSKIGSCSALRSRS------
MMAR_0415|M.marinum_M               LMTPESLSELMGGPDIEPVQST-------LQTPPGPPNAYDEYPVLPPIG
MUL_1065|M.ulcerans_Agy99           LMTPESLSELMGGPDIEPVQST-------LQTPPGPPNAYDEYPVLPPIG
MAV_5012|M.avium_104                LMTPDSLEELMGGPNIAPVQSN-------LQTPPGPPNAYDENPILPPMG
MLBr_02592|M.leprae_Br4923          LMTPDSLAELMGGPDIEPIQSN-------LQTPPGPPTAYDEHPVPPPIG
Mb0178|M.bovis_AF2122/97            LLTPESLAELMGGPDIAPPSSG-------LQTPPGPPNAYDEYPVLPPIG
Rv0172|M.tuberculosis_H37Rv         LLTPESLAELMGGPDIAPPSSG-------LQTPPGPPNAYDEYPVLPPIG
MAB_4150c|M.abscessus_ATCC_199      -PSPQDLSALMLGPDEVNAPPP-----------PGTEVRPAEPGPVPPG-
                                                        .             *.     .        

Mflv_0708|M.gilvum_PYR-GCK          --WYPQPGPPPAPAPGVVPGNPAPVNAPAP--AAPAPAAPSGPLLPAEAG
Mvan_0137|M.vanbaalenii_PYR-1       --WYPQPGPPPAPAPGVVQGNPLGAIAPAAPPAGPAPAAPSGPLLPAEAG
MSMEG_0137|M.smegmatis_MC2_155      --WYPQPGPPPAPAPGVIPGDPLSAVAPAAP-AAPAAPAPAGPPLPAEAG
TH_3020|M.thermoresistible__bu      -----SSSASSSTVRVRLASNSSRCLVNR---------------------
MMAR_0415|M.marinum_M               LQAP-VPIQPPPPGPEVIPGPVAPTPAPGPAPAP------VGAPLPAEAG
MUL_1065|M.ulcerans_Agy99           LQAP-VPIQPPPPGPEVIPGPVAPTPAPGPAPAP------VGAPLPAEAG
MAV_5012|M.avium_104                LNAP-VPIPPPPPGPGVAPGPVAPTPAPVSAPAPNA----GGPAAPADFG
MLBr_02592|M.leprae_Br4923          LQAS-VPIPS--PRPDVVPGPVAPTPSPAANVGD--------PPLPAELG
Mb0178|M.bovis_AF2122/97            LQAPQVPIPPPPPGPDVIPGPVPPTPAPVG------------APLPAEAG
Rv0172|M.tuberculosis_H37Rv         LQAPQVPIPPPPPGPDVIPGPVPPTPAPVG------------APLPAEAG
MAB_4150c|M.abscessus_ATCC_199      -----FPVTADDAPPPAIPGAPR---------------------------
                                          .  .  .      .                              

Mflv_0708|M.gilvum_PYR-GCK          GTR
Mvan_0137|M.vanbaalenii_PYR-1       G--
MSMEG_0137|M.smegmatis_MC2_155      AG-
TH_3020|M.thermoresistible__bu      ---
MMAR_0415|M.marinum_M               AGQ
MUL_1065|M.ulcerans_Agy99           AGQ
MAV_5012|M.avium_104                GGQ
MLBr_02592|M.leprae_Br4923          AGQ
Mb0178|M.bovis_AF2122/97            GGQ
Rv0172|M.tuberculosis_H37Rv         GGQ
MAB_4150c|M.abscessus_ATCC_199      ---