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VKALVAQELTGPAGLAYTDVEDVHGGDAVVLDVGAAGVCFPDLLMLRGEYQMKVPAPFVPGLEVAGTVRS APAESGFVAGQRVSAFSLLGAWAEQVAVPVGSVVPTNDALDDGSAVCLLGNYYTMHFALQRRGALQAGET VLVLGSGGGVGTASVQIAKALGARVIAMVHRPSAIEFVESLGADVVLPLTEGWLDAVKAETGGRGVDLVV DPIGGPAFDDAIRALATEGRLLVIGFAAGGIPTVKVNRLLLRNVSVVGVGWGEFVNRTPGAQAQVGAALA TLVDQGLRPPEPVRFSLSDGVAALQAFADRAVNGKLVLEPDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0107 | - | - | 100% (322) | alcohol dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1864 | - | 5e-69 | 46.58% (322) | alcohol dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4202 | - | 6e-43 | 35.35% (297) | alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0154 | - | 1e-112 | 63.04% (322) | putative quinone oxidoreductase (NADPH:quinone oxidoreductase) |
| M. gilvum PYR-GCK | Mflv_0740 | - | 1e-161 | 88.75% (320) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv0149 | - | 1e-112 | 63.04% (322) | quinone oxidoreductase |
| M. leprae Br4923 | MLBr_00118 | - | 1e-28 | 28.66% (314) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_4603c | - | 1e-109 | 61.37% (321) | oxidoreductase |
| M. marinum M | MMAR_0361 | - | 1e-116 | 66.77% (322) | quinone oxidoreductase |
| M. avium 104 | MAV_4021 | - | 1e-69 | 47.68% (323) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_0097 | - | 1e-129 | 73.52% (321) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. thermoresistible (build 8) | TH_2952 | - | 1e-120 | 68.63% (322) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. ulcerans Agy99 | MUL_4758 | - | 1e-114 | 65.53% (322) | quinone oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0107|M.vanbaalenii_PYR-1 MKALVAQELTGPAGLAYTDVEDVH-GGDAVVLDVGAAGVCFPDLLMLRGE
Mflv_0740|M.gilvum_PYR-GCK MKALVAQELTGPAGLAYTEVDEPN-GADAVVIDVGAAGVCFPDLLMLRGE
MSMEG_0097|M.smegmatis_MC2_155 MKALVAQALTGTSGLAYADVDEPV-SGDAVIIDVGAAGVCFPDLLLLRGE
TH_2952|M.thermoresistible__bu VKALVAQELSGPSGLVYTDWEDPSENDDVVVIDVRAAGLSFPDLLLIRGE
Mb0154|M.bovis_AF2122/97 MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGE
Rv0149|M.tuberculosis_H37Rv MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGE
MMAR_0361|M.marinum_M MKACVVQELSGPSGLVYTEVDDVSDGGGNVVIDVRAAGVCFPDLLLTKGE
MUL_4758|M.ulcerans_Agy99 MKACVVQELSGPSGLVYTEVDDVSDGGGNVVIDVRAAGVCLPDLLLTKGE
MAB_4603c|M.abscessus_ATCC_199 MKAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGE
MAV_4021|M.avium_104 MRAARVTRLDGPDAIEVTDVDEPT--GDGVVVDVHAAGVAFPDALLTRGL
MLBr_00118|M.leprae_Br4923 MHAIVAESAN---QMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGK
::* . : : . *:::* *:*: .* * *
Mvan_0107|M.vanbaalenii_PYR-1 YQMKVPAPFVPGLEVAGTVRSAPA-ESGFVAGQRVSAFSLLG-AWAEQVA
Mflv_0740|M.gilvum_PYR-GCK YQMKVPAPFVPGLEVAGTVRSAPD-GSGFAAGQRVSGFSLLG-AWAERVA
MSMEG_0097|M.smegmatis_MC2_155 YQMRLDPPFIPGMEVAGTVRSAPE-SSGFAPGQRVSAFTMIG-GYAEQVA
TH_2952|M.thermoresistible__bu YQLRLDPPFIPGMEIAGEVRSAPQ-GSGFRPGQRVSAFSMMG-GFAERVA
Mb0154|M.bovis_AF2122/97 YQLKLTPPFVPGMETAGVVRSAPS-DAGFHVGERVSAFGVLG-GYAEQIA
Rv0149|M.tuberculosis_H37Rv YQLKLTPPFVPGMETAGVVRSAPS-DAGFHVGERVSAFGVLG-GYAEQIA
MMAR_0361|M.marinum_M YQLKLPPPFVPGLETAGVVRSAPA-RSGFRVGERVSAFGVLG-GYAEQVA
MUL_4758|M.ulcerans_Agy99 YQLKLPPPFVPGLETAGVVRSAPA-RSGFRVGERVSAFGVLG-GYAEQVA
MAB_4603c|M.abscessus_ATCC_199 YQLKMEPPFVPGIETAGVVRSAPE-GSGIKPGDRVMAFNFIG-GYAERVA
MAV_4021|M.avium_104 YQYRPELPFVLGAEIAGVVRSAPE-GAHVRSGDRVVGLTMLSGGMAEVAV
MLBr_00118|M.leprae_Br4923 YPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGG-GYAEYVA
* . : * * ** * :.. : *:.* .: . . ** .
Mvan_0107|M.vanbaalenii_PYR-1 VPVGSVVPTNDALDDGSAVCLLGNYYTMHFALQRRGALQAGETVLVLGSG
Mflv_0740|M.gilvum_PYR-GCK LPVGSVVPTNAALDDGEAVCLLGNYYTMYFALHRRGALQPGETVLVLGSG
MSMEG_0097|M.smegmatis_MC2_155 ALPDNVIPTPENLDDASAAALLGNYYTTQFALARRGALVPGETVLVLGSA
TH_2952|M.thermoresistible__bu VAPQNVIPTADGIDDASAAALLGNYYTMYFALARRAALRPGETVLVFGSA
Mb0154|M.bovis_AF2122/97 VPVANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAA
Rv0149|M.tuberculosis_H37Rv VPVANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAA
MMAR_0361|M.marinum_M VPVSNVVRSPAELDDAEAVSLLVNYNTMYFALARRAAMRPGETVLVLGGA
MUL_4758|M.ulcerans_Agy99 VPVSNVVRSPAELDDAEAVSLLVNYNTMYFALARRAAMRPGETVLVLGGA
MAB_4603c|M.abscessus_ATCC_199 VAPSNILPTPPQLDDAEAVALIANYHTMYFAYARRGQLRAGETVLVLGAA
MAV_4021|M.avium_104 LAPDRVFKLPDNVSFEAGAGLLFNDLTVYFALTVRGRLQRGETVLVHGAA
MLBr_00118|M.leprae_Br4923 VPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHGGT
:. :. .. : * . : *: :*: *.
Mvan_0107|M.vanbaalenii_PYR-1 GGVGTASVQIAKALGA-RVIAMVHRPSAIEFVESLGADVVLPLTEGWLDA
Mflv_0740|M.gilvum_PYR-GCK GGIGTASIQIAKALGA-KVIAMVHRSSATDFVRSLGADVVLPLTDGWLDA
MSMEG_0097|M.smegmatis_MC2_155 GGIGTASIQLAKAHGA-GVIAMVHRAGAEDFVSGLGADVVLPLTDGWRDA
TH_2952|M.thermoresistible__bu GGVGTAAIQIAKAMGA-RVIAMVRRARGTEYVESLGPDVVLPLTEGWPQA
Mb0154|M.bovis_AF2122/97 GGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQ
Rv0149|M.tuberculosis_H37Rv GGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQ
MMAR_0361|M.marinum_M GGVGTAAIQIAKAMGAGQVIAVVHREGAIDYVASVGADVVLPLTEGWVDE
MUL_4758|M.ulcerans_Agy99 GGVGTAAIQIAKAMGAGQVIAVVHREGAIDYVASVGADVVLPLTEGWVEE
MAB_4603c|M.abscessus_ATCC_199 GGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKSVGADIVLPLEEGWAKA
MAV_4021|M.avium_104 GGIGTSALRLAPALGAARTIAVVSTTDKADIATAAGATDVV-LADGFKDA
MLBr_00118|M.leprae_Br4923 SGIGSHGIQVARALGA-KVAVTAGSEEKLEFCRALGAQITINYRDEDFVA
.*:*: .:::* . * . . . : . *. .: :
Mvan_0107|M.vanbaalenii_PYR-1 VKAETGGRGVDLVVDPIGGPAFDDAIRALATEGRLLVIGFAAG-GIPTVK
Mflv_0740|M.gilvum_PYR-GCK VKAETGGRGVDLVVDPIGGPAFDDAVRALATEGRLLVIGFAAG-GIPTVK
MSMEG_0097|M.smegmatis_MC2_155 VLAATDGRGVDLVVDPIGGPAFDDAVRVLAPEGRLLVIGFAAGAGIPTVK
TH_2952|M.thermoresistible__bu VRDATDGRGVDVVVDPVGGDVFDDAIRVLATEGRLLVLGFAAGQGIPTVK
Mb0154|M.bovis_AF2122/97 VRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIGFAAG-AVPTLK
Rv0149|M.tuberculosis_H37Rv VRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIGFAAG-AVPTLK
MMAR_0361|M.marinum_M VHKHTHGRGVDIVVDPIGGPVFDDAIRALAIDGKLLAIGFAAG-SIPTLA
MUL_4758|M.ulcerans_Agy99 VHKHTHGRGVDIVVDPIGGPVFDDAIHALAVDGKLLAIGFAAG-SIPTLA
MAB_4603c|M.abscessus_ATCC_199 VREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVGFAAG-GIPTIK
MAV_4021|M.avium_104 VKELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGG-EIPTVK
MLBr_00118|M.leprae_Br4923 RLQQQNG-GADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGG-VKGELN
* *.*:::* :*. : : ** *:*: :*: .* :
Mvan_0107|M.vanbaalenii_PYR-1 VNRLLLRNVSVVGVGWGEFVNRTPG----AQAQVGAALATLVDQG-LRPP
Mflv_0740|M.gilvum_PYR-GCK VNRLLLRNVSVVGVGWGEFVNRTPG----AQAEVGAALADLVDRG-LKPP
MSMEG_0097|M.smegmatis_MC2_155 VNRLLLRNVSVVGVGWGEFVRRNPG----AQAAVGAELGKLVADG-LRPP
TH_2952|M.thermoresistible__bu VNRLLLRNVGVIGVGYGEFVARNPG----AQQLFGSGLRHLVEGG-LRPP
Mb0154|M.bovis_AF2122/97 VNRLLVRNISVVGVGWGEYLNAVPG----SAALFAWGLNQLVFLG-LRPP
Rv0149|M.tuberculosis_H37Rv VNRLLVRNISVVGVGWGEYLNAVPG----SAALFAWGLNQLVFLG-LRPP
MMAR_0361|M.marinum_M VNRLLRRNVGVLGVAWGEYLNRVPG----SVYLFSWGLNHLVSLG-LRPP
MUL_4758|M.ulcerans_Agy99 VNRLLRRNVGVLGVAWGEYLNRVPG----SVYLFSWGLNHLVSLG-LRPP
MAB_4603c|M.abscessus_ATCC_199 VNRLLLRNASLIGVAWGEFLRTHAD----YLYETQAGLEKLVAEG-MRPP
MAV_4021|M.avium_104 VNRLLLNNIDVVGVGWGAWTGTHPG----ALAEQWAGLERLLTSGELAPP
MLBr_00118|M.leprae_Br4923 LGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVRPI
:.::* .. ::* .. : :: * : *
Mvan_0107|M.vanbaalenii_PYR-1 EPVRFSLSDGVAALQAFADRAVNGKLVLEPDR-----------
Mflv_0740|M.gilvum_PYR-GCK APVRYPLSDGVAALQAFADGAVNGKLVLEP-------------
MSMEG_0097|M.smegmatis_MC2_155 PPVRYRLADGAAALDAMAAGEVRGKLVLEP-------------
TH_2952|M.thermoresistible__bu PPVRFPLSEGRAAFEALAAGEVLGKAVLEP-------------
Mb0154|M.bovis_AF2122/97 PPQRYPLSEAQAALQSLDDGGVLGKVVLEP-------------
Rv0149|M.tuberculosis_H37Rv PPQRYPLSEAQAALQSLDDGGVLGKVVLEP-------------
MMAR_0361|M.marinum_M PPQRFPLSEAQAALQSLADGAVLGKIVLEP-------------
MUL_4758|M.ulcerans_Agy99 PPQRFPLSEAQAALQSLAGGAVLGKIVLEP-------------
MAB_4603c|M.abscessus_ATCC_199 VSARIPLSEGRQALQDFADGKVYGKMVLVP-------------
MAV_4021|M.avium_104 EPVVYPLDEAAAAVASLENRTAKGKVVLRVRG-----------
MLBr_00118|M.leprae_Br4923 IGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
: :. * : . ** **