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KACVVQELSGPSGLVYTEVDDVSDGGGNVVIDVRAAGVCLPDLLLTKGEYQLKLPPPFVPGLETAGVVRS APARSGFRVGERVSAFGVLGGYAEQVAVPVSNVVRSPAELDDAEAVSLLVNYNTMYFALARRAAMRPGET VLVLGGAGGVGTAAIQIAKAMGAGQVIAVVHREGAIDYVASVGADVVLPLTEGWVEEVHKHTHGRGVDIV VDPIGGPVFDDAIHALAVDGKLLAIGFAAGSIPTLAVNRLLRRNVGVLGVAWGEYLNRVPGSVYLFSWGL NHLVSLGLRPPPPQRFPLSEAQAALQSLAGGAVLGKIVLEP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4758 | - | - | 100% (322) | quinone oxidoreductase |
| M. ulcerans Agy99 | MUL_2439 | fadB4 | 6e-65 | 45.03% (322) | NADPH quinone oxidoreductase FadB4 |
| M. ulcerans Agy99 | MUL_4387 | - | 2e-44 | 35.29% (323) | quinone oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0154 | - | 1e-153 | 81.68% (322) | putative quinone oxidoreductase (NADPH:quinone oxidoreductase) |
| M. gilvum PYR-GCK | Mflv_0740 | - | 1e-115 | 65.22% (322) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv0149 | - | 1e-153 | 81.68% (322) | quinone oxidoreductase |
| M. leprae Br4923 | MLBr_00118 | - | 2e-31 | 30.16% (315) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_4603c | - | 1e-111 | 62.42% (322) | oxidoreductase |
| M. marinum M | MMAR_0361 | - | 1e-180 | 98.45% (322) | quinone oxidoreductase |
| M. avium 104 | MAV_4021 | - | 7e-68 | 45.65% (322) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_0097 | - | 1e-107 | 61.92% (323) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. thermoresistible (build 8) | TH_2952 | - | 1e-116 | 66.56% (323) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. vanbaalenii PYR-1 | Mvan_0107 | - | 1e-114 | 65.53% (322) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4758|M.ulcerans_Agy99 MKACVVQELSGPSGLVYTEVDDVSDGGGNVVIDVRAAGVCLPDLLLTKGE
MMAR_0361|M.marinum_M MKACVVQELSGPSGLVYTEVDDVSDGGGNVVIDVRAAGVCFPDLLLTKGE
Mb0154|M.bovis_AF2122/97 MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGE
Rv0149|M.tuberculosis_H37Rv MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDLLLTKGE
Mflv_0740|M.gilvum_PYR-GCK MKALVAQELTGPAGLAYTEVDEPN-GADAVVIDVGAAGVCFPDLLMLRGE
Mvan_0107|M.vanbaalenii_PYR-1 MKALVAQELTGPAGLAYTDVEDVH-GGDAVVLDVGAAGVCFPDLLMLRGE
MSMEG_0097|M.smegmatis_MC2_155 MKALVAQALTGTSGLAYADVDEPV-SGDAVIIDVGAAGVCFPDLLLLRGE
TH_2952|M.thermoresistible__bu VKALVAQELSGPSGLVYTDWEDPSENDDVVVIDVRAAGLSFPDLLLIRGE
MAB_4603c|M.abscessus_ATCC_199 MKAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGE
MAV_4021|M.avium_104 MRAARVTRLDGPDAIEVTDVDEPT--GDGVVVDVHAAGVAFPDALLTRGL
MLBr_00118|M.leprae_Br4923 MHAIVAESAN---QMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGK
::* . : : . *:::* *:*: .* * *
MUL_4758|M.ulcerans_Agy99 YQLKLPPPFVPGLETAGVVRSAPA-RSGFRVGERVSAFGVLG-GYAEQVA
MMAR_0361|M.marinum_M YQLKLPPPFVPGLETAGVVRSAPA-RSGFRVGERVSAFGVLG-GYAEQVA
Mb0154|M.bovis_AF2122/97 YQLKLTPPFVPGMETAGVVRSAPS-DAGFHVGERVSAFGVLG-GYAEQIA
Rv0149|M.tuberculosis_H37Rv YQLKLTPPFVPGMETAGVVRSAPS-DAGFHVGERVSAFGVLG-GYAEQIA
Mflv_0740|M.gilvum_PYR-GCK YQMKVPAPFVPGLEVAGTVRSAPD-GSGFAAGQRVSGFSLLG-AWAERVA
Mvan_0107|M.vanbaalenii_PYR-1 YQMKVPAPFVPGLEVAGTVRSAPA-ESGFVAGQRVSAFSLLG-AWAEQVA
MSMEG_0097|M.smegmatis_MC2_155 YQMRLDPPFIPGMEVAGTVRSAPE-SSGFAPGQRVSAFTMIG-GYAEQVA
TH_2952|M.thermoresistible__bu YQLRLDPPFIPGMEIAGEVRSAPQ-GSGFRPGQRVSAFSMMG-GFAERVA
MAB_4603c|M.abscessus_ATCC_199 YQLKMEPPFVPGIETAGVVRSAPE-GSGIKPGDRVMAFNFIG-GYAERVA
MAV_4021|M.avium_104 YQYRPELPFVLGAEIAGVVRSAPE-GAHVRSGDRVVGLTMLSGGMAEVAV
MLBr_00118|M.leprae_Br4923 YPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGG-GYAEYVA
* . : * * ** * :.. : *:.* .: . . ** .
MUL_4758|M.ulcerans_Agy99 VPVSNVVRSPAELDDAEAVSLLVNYNTMYFALARRAAMRPGETVLVLGGA
MMAR_0361|M.marinum_M VPVSNVVRSPAELDDAEAVSLLVNYNTMYFALARRAAMRPGETVLVLGGA
Mb0154|M.bovis_AF2122/97 VPVANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAA
Rv0149|M.tuberculosis_H37Rv VPVANVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAA
Mflv_0740|M.gilvum_PYR-GCK LPVGSVVPTNAALDDGEAVCLLGNYYTMYFALHRRGALQPGETVLVLGSG
Mvan_0107|M.vanbaalenii_PYR-1 VPVGSVVPTNDALDDGSAVCLLGNYYTMHFALQRRGALQAGETVLVLGSG
MSMEG_0097|M.smegmatis_MC2_155 ALPDNVIPTPENLDDASAAALLGNYYTTQFALARRGALVPGETVLVLGSA
TH_2952|M.thermoresistible__bu VAPQNVIPTADGIDDASAAALLGNYYTMYFALARRAALRPGETVLVFGSA
MAB_4603c|M.abscessus_ATCC_199 VAPSNILPTPPQLDDAEAVALIANYHTMYFAYARRGQLRAGETVLVLGAA
MAV_4021|M.avium_104 LAPDRVFKLPDNVSFEAGAGLLFNDLTVYFALTVRGRLQRGETVLVHGAA
MLBr_00118|M.leprae_Br4923 VPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHGGT
:. :. .. : * . : *: :*: *.
MUL_4758|M.ulcerans_Agy99 GGVGTAAIQIAKAMGAGQVIAVVHREGAIDYVASVGADVVLPLTEGWVEE
MMAR_0361|M.marinum_M GGVGTAAIQIAKAMGAGQVIAVVHREGAIDYVASVGADVVLPLTEGWVDE
Mb0154|M.bovis_AF2122/97 GGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQ
Rv0149|M.tuberculosis_H37Rv GGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQ
Mflv_0740|M.gilvum_PYR-GCK GGIGTASIQIAKALGA-KVIAMVHRSSATDFVRSLGADVVLPLTDGWLDA
Mvan_0107|M.vanbaalenii_PYR-1 GGVGTASVQIAKALGA-RVIAMVHRPSAIEFVESLGADVVLPLTEGWLDA
MSMEG_0097|M.smegmatis_MC2_155 GGIGTASIQLAKAHGA-GVIAMVHRAGAEDFVSGLGADVVLPLTDGWRDA
TH_2952|M.thermoresistible__bu GGVGTAAIQIAKAMGA-RVIAMVRRARGTEYVESLGPDVVLPLTEGWPQA
MAB_4603c|M.abscessus_ATCC_199 GGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKSVGADIVLPLEEGWAKA
MAV_4021|M.avium_104 GGIGTSALRLAPALGAARTIAVVSTTDKADIATAAGATDVV-LADGFKDA
MLBr_00118|M.leprae_Br4923 SGIGSHGIQVARALGA-KVAVTAGSEEKLEFCRALGAQITINYRDEDFVA
.*:*: .:::* . * . . . : . *. .: :
MUL_4758|M.ulcerans_Agy99 VHKHTHGRGVDIVVDPIGGPVFDDAIHALAVDGKLLAIGFAAG-SIPTLA
MMAR_0361|M.marinum_M VHKHTHGRGVDIVVDPIGGPVFDDAIRALAIDGKLLAIGFAAG-SIPTLA
Mb0154|M.bovis_AF2122/97 VRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIGFAAG-AVPTLK
Rv0149|M.tuberculosis_H37Rv VRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDGKLLLIGFAAG-AVPTLK
Mflv_0740|M.gilvum_PYR-GCK VKAETGGRGVDLVVDPIGGPAFDDAVRALATEGRLLVIGFAAG-GIPTVK
Mvan_0107|M.vanbaalenii_PYR-1 VKAETGGRGVDLVVDPIGGPAFDDAIRALATEGRLLVIGFAAG-GIPTVK
MSMEG_0097|M.smegmatis_MC2_155 VLAATDGRGVDLVVDPIGGPAFDDAVRVLAPEGRLLVIGFAAGAGIPTVK
TH_2952|M.thermoresistible__bu VRDATDGRGVDVVVDPVGGDVFDDAIRVLATEGRLLVLGFAAGQGIPTVK
MAB_4603c|M.abscessus_ATCC_199 VREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVGFAAG-GIPTIK
MAV_4021|M.avium_104 VKELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGG-EIPTVK
MLBr_00118|M.leprae_Br4923 RLQQQNG-GADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGG-VKGELN
* *.*:::* :*. : : ** *:*: :*: .* :
MUL_4758|M.ulcerans_Agy99 VNRLLRRNVGVLGVAWGEYLNRVPG----SVYLFSWGLNHLVSLG-LRPP
MMAR_0361|M.marinum_M VNRLLRRNVGVLGVAWGEYLNRVPG----SVYLFSWGLNHLVSLG-LRPP
Mb0154|M.bovis_AF2122/97 VNRLLVRNISVVGVGWGEYLNAVPG----SAALFAWGLNQLVFLG-LRPP
Rv0149|M.tuberculosis_H37Rv VNRLLVRNISVVGVGWGEYLNAVPG----SAALFAWGLNQLVFLG-LRPP
Mflv_0740|M.gilvum_PYR-GCK VNRLLLRNVSVVGVGWGEFVNRTPG----AQAEVGAALADLVDRG-LKPP
Mvan_0107|M.vanbaalenii_PYR-1 VNRLLLRNVSVVGVGWGEFVNRTPG----AQAQVGAALATLVDQG-LRPP
MSMEG_0097|M.smegmatis_MC2_155 VNRLLLRNVSVVGVGWGEFVRRNPG----AQAAVGAELGKLVADG-LRPP
TH_2952|M.thermoresistible__bu VNRLLLRNVGVIGVGYGEFVARNPG----AQQLFGSGLRHLVEGG-LRPP
MAB_4603c|M.abscessus_ATCC_199 VNRLLLRNASLIGVAWGEFLRTHAD----YLYETQAGLEKLVAEG-MRPP
MAV_4021|M.avium_104 VNRLLLNNIDVVGVGWGAWTGTHPG----ALAEQWAGLERLLTSGELAPP
MLBr_00118|M.leprae_Br4923 LGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVRPI
:.::* .. ::* .. : :: * : *
MUL_4758|M.ulcerans_Agy99 PPQRFPLSEAQAALQSLAGGAVLGKIVLEP-------------
MMAR_0361|M.marinum_M PPQRFPLSEAQAALQSLADGAVLGKIVLEP-------------
Mb0154|M.bovis_AF2122/97 PPQRYPLSEAQAALQSLDDGGVLGKVVLEP-------------
Rv0149|M.tuberculosis_H37Rv PPQRYPLSEAQAALQSLDDGGVLGKVVLEP-------------
Mflv_0740|M.gilvum_PYR-GCK APVRYPLSDGVAALQAFADGAVNGKLVLEP-------------
Mvan_0107|M.vanbaalenii_PYR-1 EPVRFSLSDGVAALQAFADRAVNGKLVLEPDR-----------
MSMEG_0097|M.smegmatis_MC2_155 PPVRYRLADGAAALDAMAAGEVRGKLVLEP-------------
TH_2952|M.thermoresistible__bu PPVRFPLSEGRAAFEALAAGEVLGKAVLEP-------------
MAB_4603c|M.abscessus_ATCC_199 VSARIPLSEGRQALQDFADGKVYGKMVLVP-------------
MAV_4021|M.avium_104 EPVVYPLDEAAAAVASLENRTAKGKVVLRVRG-----------
MLBr_00118|M.leprae_Br4923 IGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
: :. * : . ** **