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M. thermoresistible (build 8) TH_2876 (-)

annotation: ATPase, P-type (transporting), HAD superfamily, subfamily IC
coordinates: 1987424 - 1992250
length: 1609

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2876--100% (1609)ATPase, P-type (transporting), HAD superfamily, subfamily IC
M. thermoresistible (build 8)TH_4494-5e-7529.83% (761) PUTATIVE cation-transporting ATPase Pma1
M. thermoresistible (build 8)TH_2842-6e-7029.46% (791) PUTATIVE ATPase, P-type (transporting), HAD superfamily,

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0433cctpH0.044.11% (1417) metal cation transporting P-type ATPase CtpH
M. gilvum PYR-GCKMflv_0956-2e-6428.71% (728) ATPase, P-type (transporting), HAD superfamily, subfamily IC
M. tuberculosis H37RvRv0425cctpH0.044.25% (1417) metal cation transporting P-type ATPase CtpH
M. leprae Br4923MLBr_02671-1e-16833.40% (1410) putative cation transport ATPase
M. abscessus ATCC 19977MAB_0962-2e-4528.15% (643) cation-transporting ATPase E
M. marinum MMMAR_1228ctpH_10.058.52% (1391) metal cation transporting p-type ATPase CtpH_1
M. avium 104MAV_5219-1e-17834.91% (1501) ATPase, P-type (transporting), HAD superfamily protein, subfamily
M. smegmatis MC2 155MSMEG_3926-8e-6928.13% (750) cation-transporting ATPase Pma1
M. ulcerans Agy99MUL_4826ctpI1e-17834.36% (1464) cation-transporter ATPase I CtpI
M. vanbaalenii PYR-1Mvan_1651-0.065.22% (1360) ATPase, P-type (transporting), HAD superfamily, subfamily IC

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           ----------MPVRAVATGFRATATLTGASITAATAVSATLAKTGVGTGM
Rv0425c|M.tuberculosis_H37Rv        ----------MPVRAVATGFRATATLTGASITAATAVSATLAKTGVGTGM
TH_2876|M.thermoresistible__bu      -----MGVLRSTVGGLIGASLRTLQVAAGTALLAGD-TVIGAGRTVAGTV
Mvan_1651|M.vanbaalenii_PYR-1       --------------------------------MVTD-VASGAASTAR-AA
MMAR_1228|M.marinum_M               -------MNNSITRYLPGFGLVTAPLRAGALLAATAGSTALLGGNVAASI
MAV_5219|M.avium_104                -----------------------MVRAGVSTAAGAAGALQTLASPVAELA
MUL_4826|M.ulcerans_Agy99           MKIPGVVNPVANLVAGVTGGAVQMVRAGVQTAADAAGVLQTLASPVVELA
MLBr_02671|M.leprae_Br4923          MKIPHVTDPVSNMVG----GMAQVVRASTHAATGAVNTMQMLASPVAEFA
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           KVAIIPLRAGAKALSG---ELSRETLG----RNCWRGERRAWIEVRGLRS
Rv0425c|M.tuberculosis_H37Rv        KVAIIPLRAGAKALSG---ELSRETLG----RNCWRGERRAWIEVRGLRS
TH_2876|M.thermoresistible__bu      ADLAADVATGAESTAHTTLGLVVEALGGPPARRTSRNDSRHWIEVCGLSG
Mvan_1651|M.vanbaalenii_PYR-1       AGMVQDAAAGAPAAVQTAAAITTEALGGHPVKRSSRLNSHHWIEICGLSG
MMAR_1228|M.marinum_M               GKSLARATPDVPALARAAAGVAVEAMGGPPARRCSTNGRRRWIEVRGLSG
MAV_5219|M.avium_104                GPVIQSMAQTTGRAIGLDGSADGAP-AIVPPVRWHSGRRVHLDLDPLLPF
MUL_4826|M.ulcerans_Agy99           GPVVQSVAQTTNRAIGRNGAADGAPDGVTPPLRWHSGRRVHFDLDPLLPF
MLBr_02671|M.leprae_Br4923          WPVVQSVAKSTGRALGTGHSPNFAN-RVDPPVRWHNGQRVHLDLDPLLPF
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           GGDDELGRVVLNAIQAHPGVGSASLNYPLSRVVVAIDDPD--TSLRELCR
Rv0425c|M.tuberculosis_H37Rv        GGDDELGRVVLNAIQAHPGVGSASLNYPLSRVVVAIDDPD--TSLRELCR
TH_2876|M.thermoresistible__bu      PDADAIAEEVVSALRAVPGVTDVAINHSMARAVVTVETGV---PAADLTA
Mvan_1651|M.vanbaalenii_PYR-1       PDADAIADEVLAAVHAVAGVRHAEINRSVARVIVTTEPEG---PAENLAQ
MMAR_1228|M.marinum_M               DDAAAIAGDVLAAVRQTPGVHTAFLNRTLARLVVTLDAEAEGPSTAQLCR
MAV_5219|M.avium_104                PRWHEYAPAVEEPVRRIPGVAKAHVEGSLGRLVVELADDAD--NAAVLDE
MUL_4826|M.ulcerans_Agy99           PRWHEHAAVVEEPVRRIPGVAKAHVEGALGRLVVELEDGAD--SDTVLDE
MLBr_02671|M.leprae_Br4923          PRWHEYAAVVEEPVRRIPGVAKGHVEGSLGRLVIELDKNAD--SDVVLGK
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           IVDDAEKAERHRHPDQAADQLAQSPGSLPGDGVLLAVRAVTVAATAAGLG
Rv0425c|M.tuberculosis_H37Rv        IVDDAEKAERHRHPDQAADQLAQSPGSLPGDGVLLAVRAVTVAATAAGLG
TH_2876|M.thermoresistible__bu      VVAEAERRARTTEAG------RHRPHTLPWDDALLAARAVGAAAAAVGLG
Mvan_1651|M.vanbaalenii_PYR-1       VVADAERRVRTGPCGD-----RHRPLTLPGDDALLAARTLGALAAVAGFG
MMAR_1228|M.marinum_M               IVAAAEGRHRTRTTG-------QQPTGLPGDDVVLMGRMIAAGAATMGLG
MAV_5219|M.avium_104                VRSTVASVAADISWSKAEAAPPSAPFADPGNPLAILVPLTAAALDLVAMG
MUL_4826|M.ulcerans_Agy99           VCDTAATVAADIFLSGSASSPNSAPFADPGNPLAVLVPLTAAALDLAALG
MLBr_02671|M.leprae_Br4923          VRDVVIALAADLALTGARSAPKVAPFADPGNPLAILMPLTAAVMDLVALS
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           LALGGRALRWPRFPLVIEAAVAAVDHQPLLRRLLEDRIGTAATATVLELA
Rv0425c|M.tuberculosis_H37Rv        LALGGRALRWPRFPLVIEAAVAAVDHQPLLRRLLEDRIGTEATATVLELA
TH_2876|M.thermoresistible__bu      LSVTGNVLRFRGLPDFLSAIPTLADHNPGIHRQFERRLGREGTDLLFSLL
Mvan_1651|M.vanbaalenii_PYR-1       LSVTGNALRVPRVMELLAVVPTMAANVPQLRRQFEHRLGRDSTDLLLSLM
MMAR_1228|M.marinum_M               LSLTGSLLRLPRLPDLVAVPPTLIDHLPRLRRELEKRLGPEGTDVLFGVV
MAV_5219|M.avium_104                AAVTGWVTRLPAAPQTTRAAAALINHQPRMVSILEARLGRVGTDIALAAT
MUL_4826|M.ulcerans_Agy99           AAVTGWVIRLPAAPQTTRAAAALINHQPRMVSLLESRLGRVGTDIALAAT
MLBr_02671|M.leprae_Br4923          AAVTGWVTRLPAVPQTIRAAAALVNHQPRMVSLLESRLGRVGTDIALSIT
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           MAAAHTVTLSPAALSVDLTIQALKAAECRAGARAWRRHEPQLALHADEPA
Rv0425c|M.tuberculosis_H37Rv        MAAAHTVTLSPAALSVDLTIQALKAAECRAGARAWRRHEPQLALHADEPA
TH_2876|M.thermoresistible__bu      TSASAAMTVSPTSAAAEMATRTMMVVEAVHTRRAWRRHEPRLVRHRP--S
Mvan_1651|M.vanbaalenii_PYR-1       NAAASALTASPTSAAAEAATRTLLAAEAWDARVAWRRHEPRLAAYPP--E
MMAR_1228|M.marinum_M               NASTAALTLSPTAAAAEAATRAMLAAEAWNGRSTWFRHEPRLGSYATPDA
MAV_5219|M.avium_104                TAAAHGLTQSFGTPLLDLTQRTLQISEAAAHRRVWRDREPQLASPDRPQA
MUL_4826|M.ulcerans_Agy99           TAAANGLTQAVSTPLLDLVQRGLQISEATAHRRVWRDREPALASPGRPQA
MLBr_02671|M.leprae_Br4923          TAAASGLTQAVGTPLLDLACRGLQLSEAAAHQRVWRDREPQLASPKRPQA
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           DQPQSLWPRPARSTQ-----------------------------------
Rv0425c|M.tuberculosis_H37Rv        DQPQSLWPRPARSTQ-----------------------------------
TH_2876|M.thermoresistible__bu      SRRPHRG-TLEFGAG-----------------------------------
Mvan_1651|M.vanbaalenii_PYR-1       GGFPDRG-TLEWDYG-----------------------------------
MMAR_1228|M.marinum_M               TAATPKR-ISSPPDG-----------------------------------
MAV_5219|M.avium_104                PVVPVISSA--KSEVPRHSWAAAAAGEASHVVVGGTIDAAMDKAKGSMAG
MUL_4826|M.ulcerans_Agy99           PVVPVISSAGVQAQEPRHSWAAAAAGEASHVMVGGSIDAAIDTAKGSMAG
MLBr_02671|M.leprae_Br4923          PVVPVISSAGEKSHAAGHNWTAAASNEASHLVVGGSIDAAIDTAKGSMKG
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           PVQRSVARFALIQALSAVLVGAGTRDADMAATATLVATPKASRTTPEAFA
Rv0425c|M.tuberculosis_H37Rv        PVQRSVARFALIQALSAVLVGAGTRDADMAATATLVATPKASRTTPEAFA
TH_2876|M.thermoresistible__bu      AGERYADRAVRMGVTAAAVVGAVSRNPTIGGAAALVTAPKPSRAAREAFG
Mvan_1651|M.vanbaalenii_PYR-1       PSERYAERIGEAGLAAATIIGAVTRNPTIAASAALVTAPKPSRAARDAFG
MMAR_1228|M.marinum_M               PAERYANRIGLTGLGAAAVVGLLSRNPDSAGAAALAAVPKPLRTVREAFG
MAV_5219|M.avium_104                PVESYVDSAANGSLIAAVSALVAGGGTEDAAAAIEAGVPRAAHMGRQAFA
MUL_4826|M.ulcerans_Agy99           PVESYVNSAANGALIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQAFA
MLBr_02671|M.leprae_Br4923          PVESYVDSAANGSLIAAASALLAGGGTEDAAGAILAGVPRAAHMGQQAFA
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           AALGQGLADQHAVLPLRPESLRRLDRVDAIVIDPRVLCTDDLRVARIRGC
Rv0425c|M.tuberculosis_H37Rv        AALGQGLADQHAVLPLRPESLRRLDRVDAIVIDPRVLCTDDLRVARIRGC
TH_2876|M.thermoresistible__bu      CAMTRGLITHHDALVVRPRALRALDRVDAVVIDPRVLYTDQLAVTRIVGV
Mvan_1651|M.vanbaalenii_PYR-1       AAMTRGLTNQHDVVVVRPRALRHLDRLDAIVIDPRALYTDKLTVTRIVGV
MMAR_1228|M.marinum_M               CALSNGLTSQHDALVLRPRALRALDRVDAIMIDPRALYTDELTVSRVLGV
MAV_5219|M.avium_104                AVLGRGLANS-GQLVLDPGALRRLDRVKVVVIDGAALRGDHRAVLRVRGE
MUL_4826|M.ulcerans_Agy99           AVLGRGLASE-GQLVLDPGALRRLDRVQVVVIDGAALRGDHRSVLRAQGD
MLBr_02671|M.leprae_Br4923          ATLGRGLANA-GQLVLDPGALRRLDQVKVVVIDGAALRGDHRAVLLARGN
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           GADELSTAWNRAQLVLTESGLRPG--------------WHRVPGVSASGS
Rv0425c|M.tuberculosis_H37Rv        GADELSTAWNRAQLVLTESGLRPG--------------WHRVPGVSASGS
TH_2876|M.thermoresistible__bu      TNSDRDRAWRAVQRALDRGGLTPG--------------WHPLSSIAGAP-
Mvan_1651|M.vanbaalenii_PYR-1       TNSRRTHAWEAVRAALDADSMSPG--------------WHKLSTIPGAG-
MMAR_1228|M.marinum_M               QNSARGKAWEAVAAALDDQRLAPG--------------WHHLADIPGAG-
MAV_5219|M.avium_104                APGWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPSQGPSAMPA
MUL_4826|M.ulcerans_Agy99           EPGWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPLRGPSATPA
MLBr_02671|M.leprae_Br4923          TPGWDDDRVYEVTDALLHGERAPEPDPDESPATGARLRWVPLQGPSATPV
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           ------------DSAVEALFRPMHDRLASAVVAEAHRTGADLVSVDVDAL
Rv0425c|M.tuberculosis_H37Rv        ------------DSAVEALFRPMHDRLASAVVAEAHRTGADLVSVDVDAL
TH_2876|M.thermoresistible__bu      -------------ASGRILISPVRDQFAAAVVTEAHRCGRRVLSLDDDGL
Mvan_1651|M.vanbaalenii_PYR-1       -------------RAGKALVSPVRDPLANAVVTEARRTKPRVVSIADDGL
MMAR_1228|M.marinum_M               -------------RTGRALISPVRDPYAAAVITEARRARPRVFSLEDDGL
MAV_5219|M.avium_104                QGLESADLIVDGDRVGRVDVGWEVDPYAIPLFQTAHRTGARVVLRHVAGT
MUL_4826|M.ulcerans_Agy99           QGLEHADLVVDGQTVGNVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGT
MLBr_02671|M.leprae_Br4923          QGREHADLVVNGECVGGVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGT
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           GELRPVFDDIRPLDDGASGSLDEALARAVAELRQAGRTVAVLSSVGKQAL
Rv0425c|M.tuberculosis_H37Rv        GELRPVFDDIRPLDDGASGSLDEALARAVAELRQAGRTVAVLSSVGKQAL
TH_2876|M.thermoresistible__bu      RSLARGFDKLYPLGD----SVDESLAAAVAEAKADGATVALFTSPAMTAP
Mvan_1651|M.vanbaalenii_PYR-1       RSLAQGFDRLYPVDG----SIDEALAAAVDELKADGATVALLTTPDLSAN
MMAR_1228|M.marinum_M               RSLAQGFDHLYPSAE----SIDDAMAAALAELKAGGATVALLTTSALQAE
MAV_5219|M.avium_104                EDLTASVGATHPPGTPLLNVVRELRADRGPVLLITALHRDFASTDTLAAL
MUL_4826|M.ulcerans_Agy99           EDLSASVGSTHPPGTPLLNLVRELRTDPGPVLLITALHRDFASTDTLAAL
MLBr_02671|M.leprae_Br4923          EDLSASVGATHPPGTPLLKLVRELRTDRGPVLLITAVHRDFASTDTLAAL
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           SAADVALGVLPPPGAGAPPWYADVLLP-DLGAAWRVLHAIPAARAARQRG
Rv0425c|M.tuberculosis_H37Rv        SAADVALGVLPPPGAGAPPWYADVLLP-DLGAAWRVLHAIPAARAARQRG
TH_2876|M.thermoresistible__bu      HAADITIGLSPD--GHPPPWGADVFVP-DLVSMWRILRALPAARSATTKG
Mvan_1651|M.vanbaalenii_PYR-1       QDADLTIGLERP--GWPPPWGADVFVP-DLLSVWRILHSLPTARAVTARG
MMAR_1228|M.marinum_M               HRSDVTIGVLRA--RHPPPWGADVLVS-DLTGAWRVLHALPAARTATDSA
MAV_5219|M.avium_104                AIADVGVALDDP--RAATAWTADIITGTDLADAVRILSAIPVARSASESA
MUL_4826|M.ulcerans_Agy99           AIADIGVALDDP--RAATPWTADIITGTDLAAAVRILSAIPVARASSVSS
MLBr_02671|M.leprae_Br4923          AIADVGVALDDP--HAATPWTADIITGTDLAAAVRILSALPVARSASESS
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
Mb0433c|M.bovis_AF2122/97           NEISGGASALGALLMLPGVR----------GLGPGPVTTGAAAGLLSGYL
Rv0425c|M.tuberculosis_H37Rv        NEISGGASALGALLMLPGVR----------GLGPGPVTTGAAAGLLSGYL
TH_2876|M.thermoresistible__bu      VRLSASSTAIGALMLIPGVT----------GNGPDSVNVGVAAGLWSGFR
Mvan_1651|M.vanbaalenii_PYR-1       VRLSVSATTLGALMLIPGVP----------GSGPESVSVGVVGALWSGFT
MMAR_1228|M.marinum_M               IRLSASASAIGALMLIPSVP----------GRGSASVNVGMAVSLYLGFR
MAV_5219|M.avium_104                VHLAQGGTTLAGLLLVTGEQ-EKGASPVSFRRWLNPVNAAAATALVAGTF
MUL_4826|M.ulcerans_Agy99           VHLAQGGTTLAGLLLVTGEQ-ARTTNPASFRRWLNPVNTAAATALLSGSW
MLBr_02671|M.leprae_Br4923          VHLAQGGTTLAGLLLITASAGSKSASPITLRRWFSPVNAAAATALVTGVV
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          ---------------MSDWHARSVREVTDALDTDVTAGLTSEAAEER---
MSMEG_3926|M.smegmatis_MC2_155      ---MRRPADAGGNSNENNWHTMQPDEVLDALGASR-SGLTDSEVERR---
Mb0433c|M.bovis_AF2122/97           LARKVVDAQAPRPAPAHEWHAMSVEQVRKALPSPDEQAPAKAPPSPYPAR
Rv0425c|M.tuberculosis_H37Rv        LARKVVDAQAPRPAPAHEWHAMSVEQVRKALPSPDEQAPAKAPPSPYPAR
TH_2876|M.thermoresistible__bu      TATKVFDDSPPEPEPSHDWHALPADEVRRLLPRPGDGDRQPPAGRDP---
Mvan_1651|M.vanbaalenii_PYR-1       AGSKVFRDPPPEPESVHDWHAMPVAEVERLLPRPPD--EEPDVSTGL---
MMAR_1228|M.marinum_M               SGTKVFHDTVPEPDAGHDWHSLPIAEVQRLLPRPAE-EDRRDAENRW---
MAV_5219|M.avium_104                SATRVLRLPDPTPQPLTAWHALDPEIVYSRLAGGARPLAVET-EPSWRR-
MUL_4826|M.ulcerans_Agy99           SAATVLRLPDPTPQPLTAWHALDPEIVYARLAGGARPMAVDPGTPTWRR-
MLBr_02671|M.leprae_Br4923          SASKVLRLPDPTPQPLTAWHALDPEIVYSRLAGVTQPLAVEPGTPDWRR-
MAB_0962|M.abscessus_ATCC_1997      ---------------MATIEGLTISGLTAAEVAERVAQGKTNDVPSR---
                                                       .      :                       

Mflv_0956|M.gilvum_PYR-GCK          ---------RHRHGPNQLTEAAAVPVWRKVLRLLADKMTLVLLVAAAVSA
MSMEG_3926|M.smegmatis_MC2_155      ---------RAVHGWNRLAAVRKQSALVPFIRQFHNVLIYVMSCAAIVTA
Mb0433c|M.bovis_AF2122/97           ALAGGLHTAKRGAQITQAPLNALWQLTKAVRAELSDPLTPMLALGAMASA
Rv0425c|M.tuberculosis_H37Rv        ALAGGLHTAKRGAQITQAPLNALWQLTKAMRAELSDPLTPMLALGAMASA
TH_2876|M.thermoresistible__bu      ---ALMRPVRAAAAAMTWFWQLTRDFTAEMRSNLADPITPLLATGAVASA
Mvan_1651|M.vanbaalenii_PYR-1       ---TDLPPLRALSQAGTWSWHLTRDFVAEMRTNLSDPITPLLATGAVASA
MMAR_1228|M.marinum_M               ---EKLPPIRMVHRGTAASLRLVRDFAAEMRDDLSDPITPMLATGAAASA
MAV_5219|M.avium_104                --RLDDLSYSPALAPLRAPLQNVLRLASATRTELADPLTPILAVGAAASA
MUL_4826|M.ulcerans_Agy99           --LLDDLSYEPLVSPLRGPAHTLAQLAAATRHELADPLTPILAVGAAASA
MLBr_02671|M.leprae_Br4923          --RLDDLSYTRALSPLRKPVTKLARLASATRQEFADPLTPILAVGAAASA
MAB_0962|M.abscessus_ATCC_1997      -------------AARSVSDIVRANVFTRINAILGVLLIIVLSTGSIING
                                                                     :   :  ::  .:  ..

Mflv_0956|M.gilvum_PYR-GCK          VVSREWETPVVIMLVVTLNTVLNYVQEARAENSLQALRDMSISYSR----
MSMEG_3926|M.smegmatis_MC2_155      VLQ-HWVDAAVLFAAVLINVVIAYVQEGRAQAALDAIRAMMSPHAT----
Mb0433c|M.bovis_AF2122/97           VLG-SPVDAVMVGSVLTGNSILAASQRLRAESRLNRLLAQQIPPARKVLA
Rv0425c|M.tuberculosis_H37Rv        VLG-SPVDAVMVGSVLTGNSILAASQRLRAESRLNRLLAQQIPPARKVLA
TH_2876|M.thermoresistible__bu      LLG-SPLDAALVGGVLLLNAALSAQQQLHAERILRRLMAVQEPSARRRVR
Mvan_1651|M.vanbaalenii_PYR-1       LLG-SPLDAALVGGVLLANAALSAEQQLHAERILQRLMAVEEPLARRRVG
MMAR_1228|M.marinum_M               LLG-SPLDAFLVSSVLLLNAALSAEQQLHAERILNRLLAVQDPPARRRLG
MAV_5219|M.avium_104                IVG-SNIDALLVAGVMTVNAITGGAQRLRAESAAAELFAEQDQMVRRVVV
MUL_4826|M.ulcerans_Agy99           IVG-SNVDALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQMVRRVVV
MLBr_02671|M.leprae_Br4923          IVG-SNIDALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVV
MAB_0962|M.abscessus_ATCC_1997      AFG----------LLIIANSAVGIIQELRAKQILDKLAIVGQTRPL----
                                     .             :  *      *. :*:     :             

Mflv_0956|M.gilvum_PYR-GCK          ---------------VRRDGGEHRLPRTELVPGDVVLLEAGDAVPADGRI
MSMEG_3926|M.smegmatis_MC2_155      ---------------VTRNGRTLDVEAVELVPGDVVQLAAGDRIPADLRL
Mb0433c|M.bovis_AF2122/97           G--------------ADDQPRYIEVRAEELRPGDIIEVRTHEVVPADARV
Rv0425c|M.tuberculosis_H37Rv        G--------------ADDQPRYIEVRAEELRPGDIIEVRTHEVVPADARV
TH_2876|M.thermoresistible__bu      MATATGTGATGTEATPVEAGPIEEVPANRLRPGDVIEVRVGDVVPADARI
Mvan_1651|M.vanbaalenii_PYR-1       ---------------PLDQRRNERVSASRLRPGDIIEVHADEVVPADARL
MMAR_1228|M.marinum_M               ---------------PLDEQRREKVPAKRLRPGDIIEVHADEVVPADARL
MAV_5219|M.avium_104                PAVATTRR---RLEAARHATRTATVSAKSLRPGDVIDLAAPEVVPADARL
MUL_4826|M.ulcerans_Agy99           PAVATTRR---RLEAARHATRTATVSAKSLRVGDVIDLAAPEVVPADARL
MLBr_02671|M.leprae_Br4923          PAVATTRR---RLEAAQHATRTVTVSAKSLRAGDVIDLAAPEVVPADARV
MAB_0962|M.abscessus_ATCC_1997      ---------------VRRDGAATALAPNEVVLDDIIELGPGDQIVVDGEV
                                                            :    :  .*:: :   : : .* .:

Mflv_0956|M.gilvum_PYR-GCK          VSAARLQVAESALTGESAPVDKAVDGLDDTDLPLGDRTNMLYMNTEVTRG
MSMEG_3926|M.smegmatis_MC2_155      IGVDGLQVDEAPLTGESAPVWKTIG-VDDEDTSLPDRRSMAYSGTLAIHG
Mb0433c|M.bovis_AF2122/97           IEEVDVEVDESALTGESLSVTKQVE--PTPGVDLIERRCMLYAGTTVVSG
Rv0425c|M.tuberculosis_H37Rv        IEEVDVEVDESALTGESLSVTKQVE--PTPGVDLIERRCMLYAGTTVVSG
TH_2876|M.thermoresistible__bu      MAASNVEVDESSLTGESLPVPKTAA--ATPGAPLAERSGMLYAGTTMVAG
Mvan_1651|M.vanbaalenii_PYR-1       IEATNIEVDESSLTGESLPVPKQTD--PTPGAPLAERACMLYAGSTLVAG
MMAR_1228|M.marinum_M               LHASSVEVDESTLTGESLPVSKQTE--PTPGAPLAERACMLYAGTTMVAG
MAV_5219|M.avium_104                LEAEDLEVDESLLTGESLPVDKQVE--PVA-VNDPDRASMLFEGSTIVAG
MUL_4826|M.ulcerans_Agy99           LVAEDLEVDESLLTGESLPVDKQVD--PVA-VNDADRASMLFEGSTIVAG
MLBr_02671|M.leprae_Br4923          LVAEDLEVDESLLTGESLPVDKRVD--PVA-INDADRASMLFEGSAIVAG
MAB_0962|M.abscessus_ATCC_1997      IEESALEIDESLLTGEADAIEKTIG-------------SQVLSGSFVVAG
                                    :    ::: *: ****: .: *                     .:    *

Mflv_0956|M.gilvum_PYR-GCK          RATMVVTATGMDTEVGAIATMLGTAGVSRTPLQQRIDNLAQMLTVVALLV
MSMEG_3926|M.smegmatis_MC2_155      QATGVVVGTGAQTELGRINHLLTGVAPTATPLLRQISRFGRVLAVVILLL
Mb0433c|M.bovis_AF2122/97           TAVAVVTAVGPDTQERRAAELVSGDLSSVG-LQHQLSRLTNQAWPVSMTG
Rv0425c|M.tuberculosis_H37Rv        TAVAVVTAVGPDTQERRAAELVSGDLSSVG-LQHQLSRLTNQAWPVSMTG
TH_2876|M.thermoresistible__bu      TAVAVVTAVGPRTEVRRALAMAAERPGEIG-LQRQLAHITKRALPFSVSS
Mvan_1651|M.vanbaalenii_PYR-1       TAVAVVTTVGSRTEMRRALAMAPDKSREIG-LQRQLSRITKRALPFSVGG
MMAR_1228|M.marinum_M               TAVAVVTAVGSRSEMRRALAMAPRKSREIG-LQRQLSRITRRALPFSVAS
MAV_5219|M.avium_104                HARAIVVATGVGTAAHRAISAVADVETAAG-VQARLRELTSKVLPLTLAG
MUL_4826|M.ulcerans_Agy99           RARAIVVATGAGTAAHRAISAVADVETSAG-VQARLRELTSKVLPLTLAG
MLBr_02671|M.leprae_Br4923          HARAIVVATGVGTAAHRAISAVADVEVSAG-VQARLRELTSKVLPLTLAG
MAB_0962|M.abscessus_ATCC_1997      SGAYRATKVGREAYAAKLAEEASKFTLVHSELRNGINKILQFITYLLLPA
                                     .   .. .*  :                  :   : .:      . :  

Mflv_0956|M.gilvum_PYR-GCK          VIVVTVLG-LLRGDTWTELLLTAVSLAVATIPEGLTAVVAFTLAMGASRL
MSMEG_3926|M.smegmatis_MC2_155      SAATYALGVIWRGETLTEMFMMTVALAASAIPEGLPAIMTVTLAIGVQRM
Mb0433c|M.bovis_AF2122/97           GALVTGLG-LLRRRGLRQAVASGIAVTVAAVPEGMPLVATLAQQASARRL
Rv0425c|M.tuberculosis_H37Rv        GALVTGLG-LLRRRGLRQAVASGIAVTVAAVPEGMPLVATLAQQASARRL
TH_2876|M.thermoresistible__bu      GALVGLLS-VLRGTPIRAAVGSAVSLIVAAVPEGLPLVATLAQLASARRL
Mvan_1651|M.vanbaalenii_PYR-1       GALVGLLS-LARGTPLREAVGSSVALTVAAVPEGLPLVATLAQLASARRL
MMAR_1228|M.marinum_M               GGLVGLLS-MSRGTPLREAVASAVTLVVAAVPEGLTLVVTLAQLAAARRL
MAV_5219|M.avium_104                GAAVSTLA-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLSAAQRL
MUL_4826|M.ulcerans_Agy99           GASVSVLA-LMRRATLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRL
MLBr_02671|M.leprae_Br4923          GAAVTGLA-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRL
MAB_0962|M.abscessus_ATCC_1997      GALIIYTQLFTTDDSWQESVLRMVGALVPMVPEGLVLMTSIAFAVGVIRL
                                             .         .   :   .. :***:  : :.:   .. *:

Mflv_0956|M.gilvum_PYR-GCK          ARRGAIIKQLSAVETLGSTADIATDKTGTLTLNEMTVRRLLLPGREFRVS
MSMEG_3926|M.smegmatis_MC2_155      SRRRAIVCRLPAVEALGSVTVICTDKTGTLTSNEMTVQRVVCGGHDIDVG
Mb0433c|M.bovis_AF2122/97           SHFGALVRIPRSVEALGRVDMVCFDKTGTLSENRLRVAQVRP--------
Rv0425c|M.tuberculosis_H37Rv        SHFGALVRIPRSVEALGRVDMVCFDKTGTLSENRLRVAQVRP--------
TH_2876|M.thermoresistible__bu      SGESILIRNPNSIEALARLQVVCFDKTGTLSENRLQVKAVHP--------
Mvan_1651|M.vanbaalenii_PYR-1       TGESVLIRNAQSIEAMARLQVVCFDKTGTLSENRLRVKAVRP--------
MMAR_1228|M.marinum_M               TGESVLIRNAHSIEALARLNVVCFDKTGTLSENRLKVKTVRP--------
MAV_5219|M.avium_104                TARGALVRAPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPDDV-----
MUL_4826|M.ulcerans_Agy99           TAHGALVRAPRTIEALGRVDTVCFDKTGTLTENRLRVVCAIPSST-----
MLBr_02671|M.leprae_Br4923          TAKGALVRSPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPNTR-----
MAB_0962|M.abscessus_ATCC_1997      GRRQCLVQELPAIEGLARVDTVCADKTGTLTENGMRLADVHFPDR-----
                                         ::    ::* :.    :. ******: * : :             

Mflv_0956|M.gilvum_PYR-GCK          GEGYSTDGKILVS----DGRPLPDLTAPLLAMALCSDASVREG----SLV
MSMEG_3926|M.smegmatis_MC2_155      GVGYAPVGDFSIDGRVIDPSRYPALMEALLAASLCNDASLDVEDEVWVIT
Mb0433c|M.bovis_AF2122/97           -------------------------VAGHSREEVLRCAAHAAPASNGP-Q
Rv0425c|M.tuberculosis_H37Rv        -------------------------VAGHSREEVLRCAAHAAPASNGP-Q
TH_2876|M.thermoresistible__bu      -------------------------MRGRTETEVLEAALSTTFAEPGHRA
Mvan_1651|M.vanbaalenii_PYR-1       -------------------------IDGFTEEQALDAALSTIFVRAGHRA
MMAR_1228|M.marinum_M               -------------------------APGFTPGQVLDAALSTTYSRHTHRV
MAV_5219|M.avium_104                ----------------NPHDPFPELTAPQSAELVRAAARASARPQEGQGH
MUL_4826|M.ulcerans_Agy99           ----------------SPLDPFIDSADPRSTEVLRAAARATTQPHDGQGH
MLBr_02671|M.leprae_Br4923          ----------------MPHDPLPDITDPHSAAVLRDAARASTQPHDGQGH
MAB_0962|M.abscessus_ATCC_1997      -----------------------------------DGDEDALAVLAQLAA
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          GDPTEGALVVLAEKGGVDVTGARAA--IPRLAEVPFDSEYKYMATFCARS
MSMEG_3926|M.smegmatis_MC2_155      GDPTEAALLVVAKKAGLDHDRETVS--HPRVATVPFASENRIMGTLHS--
Mb0433c|M.bovis_AF2122/97           VHATDVAIVQAAAAAAASGTDGAEPGAAEPAAHLPFRSGRSFSASVSGTE
Rv0425c|M.tuberculosis_H37Rv        VHATDVAIVQAAAAAAASGTDGAEPGAAEPAAHLPFRSGRSFSASVSGTE
TH_2876|M.thermoresistible__bu      HHATDEAIIRAVNG---AAIAAPAQ----RDGFLPFQAGRPYAAAVRGTR
Mvan_1651|M.vanbaalenii_PYR-1       HHATDDAIRRAVHGDEDAADTTEIE----RDAFLPFQAGRPFAAAIVGTR
MMAR_1228|M.marinum_M               EHATDDAIFQAADDPAVRGDGSQPQPRLSRDAFLPFQSGRPFAAALAGTR
MAV_5219|M.avium_104                AHATDEAILTAASSLNGQRDS-----DWSMIAEVPFESSRGFAAAIGTVG
MUL_4826|M.ulcerans_Agy99           AHATDEAIIVAANSLEGLNDS-----AWTVIAEVPFESSRGYAASIGTTG
MLBr_02671|M.leprae_Br4923          THATDEAILTAASSLNSHTDS-----TWSLIAEVPFESSRGYAAAIGITG
MAB_0962|M.abscessus_ATCC_1997      DDPRPNASIAAIAEAYDTPPG------WETTAIAPFSSAKKWSGASYGEH
                                     ..   *                        .  ** :     .:     

Mflv_0956|M.gilvum_PYR-GCK          DLDGSGGH--RCFVKGAPGVLLEHAGSVLGEDGPRPIDPGYRQRIRERVE
MSMEG_3926|M.smegmatis_MC2_155      DVDRTP----LIVVKGAPERVLDICDSQRSPHGEEPLDRLYWQRMAA---
Mb0433c|M.bovis_AF2122/97           -----------LTVKGAPEVVLAACEGIG-----SSMDDAVAE-------
Rv0425c|M.tuberculosis_H37Rv        -----------LTVKGAPEVVLAACEGIG-----SSMDDAVAE-------
TH_2876|M.thermoresistible__bu      -----------LTIKGAPEVLASALARG-----DSALTRRVEA-------
Mvan_1651|M.vanbaalenii_PYR-1       -----------LTIKGAPEVLASALAQA-----NGPAVAAIDD-------
MMAR_1228|M.marinum_M               -----------LTIKGSPEVLSAALRRAPEAA-ADPFTKQIDE-------
MAV_5219|M.avium_104                NANGNPSDTPVLILKGAPEVILPRCRFADPEADQQRAEAVVRG-------
MUL_4826|M.ulcerans_Agy99           TSNGHPT----LMLKGAPETILPRCRFADPDADLEHAEALVHS-------
MLBr_02671|M.leprae_Br4923          --NGKAP---MLMLKGAPEKILPRCRFADPEADVAHAESLVRH-------
MAB_0962|M.abscessus_ATCC_1997      G----------NWVIGAPDVLLDP---------ADAIATAAEE-------
                                                 : *:*  :                             

Mflv_0956|M.gilvum_PYR-GCK          QLASEGLRTLMIAGRDIDHDLPADPDGLQTLVD-----DLTVYAVVGIVD
MSMEG_3926|M.smegmatis_MC2_155      TTAAQGLRVLAIARR-CGAPRNAGTLDIADLDS-----GFTMLGLVGIID
Mb0433c|M.bovis_AF2122/97           -LAANGLRVIAVAHRQLTAQQAQSVVDDPDEIARLCRDELSLVGFLGLSD
Rv0425c|M.tuberculosis_H37Rv        -LAANGLRVIAVAHRQLTAQQAQSVVDDPDEIARLCRDELSLVGFLGLSD
TH_2876|M.thermoresistible__bu      -MAAQGLRVLAVAGRELSPEQAAAAVADPAVFTELCGSGLSLFGLIGLAD
Mvan_1651|M.vanbaalenii_PYR-1       -MAAKGLRVIAVAERQLTPEQAAAAAADAAAFEELCRSDLTPIGLLGLAD
MMAR_1228|M.marinum_M               -MATGGLRVLAVAERQLRPEQATAAAADPDLLESLCQSELTPVGLLGLAD
MAV_5219|M.avium_104                -LAEQGLRVLAVAQRGWKHDTDDDD-TDADAVDAAAH-NLELLGYVGLAD
MUL_4826|M.ulcerans_Agy99           -LAERGLRVLAVAKRPWEHDTADDDDTDADAVDAAAH-DLELLGYVGLAD
MLBr_02671|M.leprae_Br4923          -LAEQGLRVLAVAQCSWGHDTTDDNDTDADAVDAAAH-DLELVGYIGLAD
MAB_0962|M.abscessus_ATCC_1997      -IGARGLRVLLLASAELSVDDAHAP------------GAVTPRALVVLEQ
                                      .  ***.: :*                          .   . : : :

Mflv_0956|M.gilvum_PYR-GCK          PPRPEAGEAIATAHAAGITVHMITGDHLSTAAAVAHDLGIPG--AAASG-
MSMEG_3926|M.smegmatis_MC2_155      ALRPEVAAAVRECHRAGIRVKMITGDHAATAREIGAQLGIGIGKPAVIG-
Mb0433c|M.bovis_AF2122/97           TPRAQAAALLADLHEHDLDIRLITGDHPITAAAIAEELGMQVSPEQVISG
Rv0425c|M.tuberculosis_H37Rv        TPRAQAAALLADLHEHDLDIRLITGDHPITAAAIAEELGMQVSPEQVISG
TH_2876|M.thermoresistible__bu      TPRPSARGVLADLTERGIGVRLITGDHPVTAAVTARELGLDVDGEQVITG
Mvan_1651|M.vanbaalenii_PYR-1       TPRASAQDVLKELGNRGIGVRLITGDHPVTAMVIAGELGLDVTAEQVMTG
MMAR_1228|M.marinum_M               TPRPTAQSVLNGLADRDIGVRLITGDHPATATATAQELGLDVTDSEVITG
MAV_5219|M.avium_104                TARASARPLIEALLDAERDVVLITGDHPITARAIARQLGLPADAR-VVTG
MUL_4826|M.ulcerans_Agy99           TARPSARPLIEALVDAQRNVVLITGDHPITARAIARQLGLPEDVR-VVTG
MLBr_02671|M.leprae_Br4923          TARPSSRPLIEALVTAGRNVVLITGDHPITARAIAQQLGLRSDAR-VVNG
MAB_0962|M.abscessus_ATCC_1997      KIRPDARETLDYFASQHVSIKVISGDNAVSVSAVAQTLGLTG----AAVD
                                      *.     :         : :*:**:  :.   .  **:      .   

Mflv_0956|M.gilvum_PYR-GCK          ADLDRLDDDTLREQSPSFGVLARVAPEHKIRLVKALQSRGHVVAMTGDGV
MSMEG_3926|M.smegmatis_MC2_155      SEIASLNDTDLQTVVQERDIFARASPEHKLRLVRALQAGGEVVAMTGDGV
Mb0433c|M.bovis_AF2122/97           AEWDALSRKDQERAVAERVIFARMTPENKVQIVQTLEHSGRVCAMVGDGS
Rv0425c|M.tuberculosis_H37Rv        AEWDALSRKDQERAVAERVIFARMTPENKVQIVQTLEHSGRVCAMVGDGS
TH_2876|M.thermoresistible__bu      AEWETLSAEERAAAVRSRSVFARMSPEHKIDVVQTLERNGVVTAMVGDGA
Mvan_1651|M.vanbaalenii_PYR-1       AEWEGLSAEERSEAVVSRIVYARMSPEHKIDVVQTLERIGMVTAMVGDGA
MMAR_1228|M.marinum_M               AEWEALSADQRATVVASRLVFARMSPEHKVEVVQALERAGLVTAMVGDGV
MAV_5219|M.avium_104                AELAGLDEDACAKLVADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDGA
MUL_4826|M.ulcerans_Agy99           AELIGLDEDACAKLAADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDGA
MLBr_02671|M.leprae_Br4923          TELIGLDEDACAELAADVQVFARVSPEQKVQIVAALQRCGQVTAMVGDGA
MAB_0962|M.abscessus_ATCC_1997      ARTLPTDTDKLAATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDGV
                                    :     .         .    .*  *::*  :* :*:  * . **.*** 

Mflv_0956|M.gilvum_PYR-GCK          NDAPALKQADIGIAMGITGTDVSKGAANMILTDDNFGTIVAAVREGRGIY
MSMEG_3926|M.smegmatis_MC2_155      NDSPALKKADVGIAMGCRGTEAAKEAADMVLADDNFATIAAAVSEGRTVY
Mb0433c|M.bovis_AF2122/97           NDAAAIRAATVGIGVVAHGSDPARVAADLVLVDGRIESLLPAILEGRQLW
Rv0425c|M.tuberculosis_H37Rv        NDAAAIRAATVGIGVVAHGSDPARVAADLVLVDGRIESLLPAILEGRQLW
TH_2876|M.thermoresistible__bu      NDAAAIRAASVGVGVATRSSDPARTAADIVLLDGRIEALIDALDEGHHLW
Mvan_1651|M.vanbaalenii_PYR-1       NDAAAIRAASVGFGVASRGSDPARTAADVVLLDGRIEALLDALDEGKQLW
MMAR_1228|M.marinum_M               NDAAAIRAASVGIGMAARGSDAARTAADVVLLDGRIDALLEALDEGQQLW
MAV_5219|M.avium_104                NDAAAIRMADVGIGVSGRGSSAARGAADIVLTDQDLSVLLDALVEGRSMW
MUL_4826|M.ulcerans_Agy99           NDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMW
MLBr_02671|M.leprae_Br4923          NDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMW
MAB_0962|M.abscessus_ATCC_1997      NDVLALKDADIGVAMG-AGSSASRAVAQIVLLDNKFATLPYVVAEGRRVI
                                    **  *:: * :*..:   .:. :: .*:::* *  :  :  .: **: : 

Mflv_0956|M.gilvum_PYR-GCK          ANIIKFVKFQLTTAWGFVLIFLVCGSLGLAG-GAPFTALQILWVNIIMDG
MSMEG_3926|M.smegmatis_MC2_155      DNIRKFVLFMLPTNGGEALVVIAAILFQFT---LPLTPAQVLWINLVTSS
Mb0433c|M.bovis_AF2122/97           QRVQAAVSVLLGGNAGEVAFAIIGSAITG---TSPLNTRQLLLVNMLTDA
Rv0425c|M.tuberculosis_H37Rv        QRVQAAVSVLLGGNAGEVAFAIIGSAITG---TSPLNTRQLLLVNMLTDA
TH_2876|M.thermoresistible__bu      RRVQSAVSMLLGGNSGEIAFALLTSLLTG---RSVLNARXXXTTAADAEP
Mvan_1651|M.vanbaalenii_PYR-1       RRVQSAVSMLLGGNTGEIAFALITSLLTG---RSVLNARQMLLVNMLTDA
MMAR_1228|M.marinum_M               RRVHSAVSVLLGGNLGEVSFALITTLLTG---RSVFNARQMLLVNMLTDA
MAV_5219|M.avium_104                AGVRDAVTILVGGNVGEVLFTIIGTAFGAG--RAPVGTRQLLLVNLLTDM
MUL_4826|M.ulcerans_Agy99           AGVRDAVTILVGGNVGEVLFTIIGTAFGAG--RAPVGTRQLLLVNLLTDM
MLBr_02671|M.leprae_Br4923          AGVRDAVTILVGGNVGEVVFTIIGTVFGAG--RAPVGTRQLLLVNLLTDM
MAB_0962|M.abscessus_ATCC_1997      GNIERVSNLFLTKTVYSVLLALTVGLAGLGSKIFHYGAVPFPFQPIHVTI
                                      :     . :        . :               .            

Mflv_0956|M.gilvum_PYR-GCK          PPALALGVDPTEPDVMHQKPR---------------------PPTERLLN
MSMEG_3926|M.smegmatis_MC2_155      TLGLALAFEPPEAGVMRRKPR---------------------APSESLLS
Mb0433c|M.bovis_AF2122/97           LPAAALAVSKPSDPVTPATRG----------------------PDQRELW
Rv0425c|M.tuberculosis_H37Rv        LPAAALAVSKPSDPVTPATRG----------------------PDQRELW
TH_2876|M.thermoresistible__bu      IPCKARAIPSMVMSGATAHS------------------------TDASMC
Mvan_1651|M.vanbaalenii_PYR-1       LPAAALAVSRQTDTTGQVDL------------------------DEAAMW
MMAR_1228|M.marinum_M               LPAAALAVSPQTSN-VEVER------------------------DEAAMW
MAV_5219|M.avium_104                FPALAVAVTSQYVEPDEAEYPSAADAEAARREHRRAVLTGPTPSLDAPLM
MUL_4826|M.ulcerans_Agy99           FPALAVAITSQYDDPEDDSDLSDEEIEEARRRRQRAVLTAPTPSLDAPLM
MLBr_02671|M.leprae_Br4923          FPALSIAVTSQYEEPGEDEYQTDEEADEARRTHQHEVLTGPTPSLDAPLM
MAB_0962|M.abscessus_ATCC_1997      AAWFTIGIPAFILSLAPNNER-----------------------AQTGFV
                                        : ..                                     :  : 

Mflv_0956|M.gilvum_PYR-GCK          RARLQRILVLG-MVMTLGTVTVLMLADDLFPESAGDPLFATTLAFTTFVF
MSMEG_3926|M.smegmatis_MC2_155      RHFAWRVLLVS-VLMAGGALGMFLWE----LRSGTSVETARTMAVNAIVA
Mb0433c|M.bovis_AF2122/97           RAVGIRG-----ATTAAAATVAWVMAGFTGLPRRA---------STVALV
Rv0425c|M.tuberculosis_H37Rv        RAVGIRG-----ATTAAAATVAWVMAGFTGLPRRA---------STVALV
TH_2876|M.thermoresistible__bu      TAIPAISGRRRPNESDRGPTTSWPSASPTSVPVNVSCATDDDTFSSSAIR
Mvan_1651|M.vanbaalenii_PYR-1       RAIGVRG-----AATTVGATSAWAMASMTGTPQRA---------STVALI
MMAR_1228|M.marinum_M               RAIGIRG-----ASTTTGAMLAWLMASATGTRRRA---------ATVALI
MAV_5219|M.avium_104                RQIVTRG-----AVTAAGATAAWAIGRWTPGTERR--------TATMGLT
MUL_4826|M.ulcerans_Agy99           RQIANRG-----VVTAAGATAAWAIGRWTPGTERR--------TATMGLT
MLBr_02671|M.leprae_Br4923          RQIVNRG-----VVTAAGATTAWAIGRWTPGTERR--------TATMGLT
MAB_0962|M.abscessus_ATCC_1997      RRVMLSAIPSG-LTVGIATFLSYLLARQILHVSGN--------STQASTA
                                                     ..                               

Mflv_0956|M.gilvum_PYR-GCK          YQVFNLLNVRSDTGSAFSRQ-TFTNGAIWVS----------------LAA
MSMEG_3926|M.smegmatis_MC2_155      AEMFYLLNNRFLLEPVLNRIGLFGNKIAFAT----------------VVA
Mb0433c|M.bovis_AF2122/97           A----LVAAQLGQTLVD-SHAWLVVLTALGS---------------LAAL
Rv0425c|M.tuberculosis_H37Rv        A----LVAAQLGQTLVD-SHAWLVVLTALGS---------------LAAL
TH_2876|M.thermoresistible__bu      GSAGRYMSMVSGPRVIS-APSIRIMRVRLGIPLGVRGDVRSERATAFDSA
Mvan_1651|M.vanbaalenii_PYR-1       G----LVSTQLAQTLID-SRSPLVVATALGS---------------FATL
MMAR_1228|M.marinum_M               G----LVGTQLTQTVAD-SHGPLVVLTTVGS---------------FGVL
MAV_5219|M.avium_104                A----LVTTQLAQTLLTRRHSPLVVATALGS---------------AGVL
MUL_4826|M.ulcerans_Agy99           A----LVTTQLAQTLLTRSHSPLVLATAFGS---------------AGVL
MLBr_02671|M.leprae_Br4923          A----LVTTQLAQTLLTRRHSPLVVATALGS---------------AGVL
MAB_0962|M.abscessus_ATCC_1997      ALITELVAAVWVLAVVARPYQWWRVALVALSG---------------LGY
                                          :                                           

Mflv_0956|M.gilvum_PYR-GCK          VIVLQVLVVQLDVLQNLFDTTELTSAQ-------WLFAIAVGSSVLVVDE
MSMEG_3926|M.smegmatis_MC2_155      CTALQLVFTYAPAMNAVFGSTPLGYVD-------WIKAAAVGAPVFGVVE
Mb0433c|M.bovis_AF2122/97           ATLISIP-----VVSQLLGCTPLDPLG-------WAQATAAATAATVAVA
Rv0425c|M.tuberculosis_H37Rv        ATLISIP-----VVSQLLGCTPLDPLG-------WAQATAAATAATVAVA
TH_2876|M.thermoresistible__bu      TEVLSDANHLFCSRTRGFGARVVAHIGGTRQALAWAQPLRHREAAAHERM
Mvan_1651|M.vanbaalenii_PYR-1       AGVISTP-----GVSQVFGCTPVGPVG-------WGQAFSATAVAALLSA
MMAR_1228|M.marinum_M               AVVVTTP-----GLSHLFGCTPVGPLA-------WGQALLAAAVAGSASV
MAV_5219|M.avium_104                VGIVQTP-----VLSQFFGCTPLGPVA-------WTGVLGSTAGATAISA
MUL_4826|M.ulcerans_Agy99           IGIIQTP-----VVSHFFGCTPLGPVA-------WTGVFSATAGATAVSA
MLBr_02671|M.leprae_Br4923          IGIIQTP-----VISQFFGCTPLGPIA-------WSGVITATAGATAVSV
MAB_0962|M.abscessus_ATCC_1997      VAIFAIP---LARKAFMLDPGNLAVTG---------PALGIGIAAAAVIE
                                       .             :.   :                     .     

Mflv_0956|M.gilvum_PYR-GCK          IGKAVVRTAR----------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      LEKFMVR-------------------------------------------
Mb0433c|M.bovis_AF2122/97           VLNRVLTGRD------------------------------KSGQPNPQPP
Rv0425c|M.tuberculosis_H37Rv        VLNRVLTGRD------------------------------KSGQPNPQPP
TH_2876|M.thermoresistible__bu      VPREGPVGRDTRHSIRWGVRWGVRWGARSGGGGAGADRDHRTRLPGAGPR
Mvan_1651|M.vanbaalenii_PYR-1       TAPELLN------------------------------------------R
MMAR_1228|M.marinum_M               IAPELLM------------------------------------------R
MAV_5219|M.avium_104                LAP-----------------------------------------------
MUL_4826|M.ulcerans_Agy99           LAP-----------------------------------------------
MLBr_02671|M.leprae_Br4923          LAP-----------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      AVWWLQG-------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          -----RRRRRRVSGADRPREARPASGR-----------------------
MSMEG_3926|M.smegmatis_MC2_155      -----RRKARAALAGEEPKGGHTAAHR-----------------------
Mb0433c|M.bovis_AF2122/97           ETDALSRDASPGAPPGPRRRRRATARRKAPVKAPSATRQTTKPKGPPAHR
Rv0425c|M.tuberculosis_H37Rv        ETDALSRDASPGAPPGPRRRRRATARRKAPVKAPSATRQTTKPKGPPAHR
TH_2876|M.thermoresistible__bu      GARLRRPVAQQVPRRLPGQDRHQAGETLSGDRGGQRGGGRFHRRRAGRGH
Mvan_1651|M.vanbaalenii_PYR-1       ATDAVRKRVADVVESVPVVDDDDAGLDEDGVEGADR------RRQQ----
MMAR_1228|M.marinum_M               VSRQAQRLISVTADGQATVQEREAGAPT----------------------
MAV_5219|M.avium_104                -----NWLAKQVAALEPGQQDA----------------------------
MUL_4826|M.ulcerans_Agy99           -----KWLAKTVDVALEHQDWASGSA------------------------
MLBr_02671|M.leprae_Br4923          -----QWLNKAFGIAQLNQE------------------------------
MAB_0962|M.abscessus_ATCC_1997      -----KWSGQPRHFWATGDD------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          ---------
MSMEG_3926|M.smegmatis_MC2_155      ---------
Mb0433c|M.bovis_AF2122/97           SSSTYPRR-
Rv0425c|M.tuberculosis_H37Rv        SSSTYPRR-
TH_2876|M.thermoresistible__bu      IGRALGGDR
Mvan_1651|M.vanbaalenii_PYR-1       --MDTGGD-
MMAR_1228|M.marinum_M               ---------
MAV_5219|M.avium_104                ---------
MUL_4826|M.ulcerans_Agy99           ---------
MLBr_02671|M.leprae_Br4923          ---------
MAB_0962|M.abscessus_ATCC_1997      ---------