For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PVRAVATGFRATATLTGASITAATAVSATLAKTGVGTGMKVAIIPLRAGAKALSGELSRETLGRNCWRGE RRAWIEVRGLRSGGDDELGRVVLNAIQAHPGVGSASLNYPLSRVVVAIDDPDTSLRELCRIVDDAEKAER HRHPDQAADQLAQSPGSLPGDGVLLAVRAVTVAATAAGLGLALGGRALRWPRFPLVIEAAVAAVDHQPLL RRLLEDRIGTEATATVLELAMAAAHTVTLSPAALSVDLTIQALKAAECRAGARAWRRHEPQLALHADEPA DQPQSLWPRPARSTQPVQRSVARFALIQALSAVLVGAGTRDADMAATATLVATPKASRTTPEAFAAALGQ GLADQHAVLPLRPESLRRLDRVDAIVIDPRVLCTDDLRVARIRGCGADELSTAWNRAQLVLTESGLRPGW HRVPGVSASGSDSAVEALFRPMHDRLASAVVAEAHRTGADLVSVDVDALGELRPVFDDIRPLDDGASGSL DEALARAVAELRQAGRTVAVLSSVGKQALSAADVALGVLPPPGAGAPPWYADVLLPDLGAAWRVLHAIPA ARAARQRGNEISGGASALGALLMLPGVRGLGPGPVTTGAAAGLLSGYLLARKVVDAQAPRPAPAHEWHAM SVEQVRKALPSPDEQAPAKAPPSPYPARALAGGLHTAKRGAQITQAPLNALWQLTKAMRAELSDPLTPML ALGAMASAVLGSPVDAVMVGSVLTGNSILAASQRLRAESRLNRLLAQQIPPARKVLAGADDQPRYIEVRA EELRPGDIIEVRTHEVVPADARVIEEVDVEVDESALTGESLSVTKQVEPTPGVDLIERRCMLYAGTTVVS GTAVAVVTAVGPDTQERRAAELVSGDLSSVGLQHQLSRLTNQAWPVSMTGGALVTGLGLLRRRGLRQAVA SGIAVTVAAVPEGMPLVATLAQQASARRLSHFGALVRIPRSVEALGRVDMVCFDKTGTLSENRLRVAQVR PVAGHSREEVLRCAAHAAPASNGPQVHATDVAIVQAAAAAAASGTDGAEPGAAEPAAHLPFRSGRSFSAS VSGTELTVKGAPEVVLAACEGIGSSMDDAVAELAANGLRVIAVAHRQLTAQQAQSVVDDPDEIARLCRDE LSLVGFLGLSDTPRAQAAALLADLHEHDLDIRLITGDHPITAAAIAEELGMQVSPEQVISGAEWDALSRK DQERAVAERVIFARMTPENKVQIVQTLEHSGRVCAMVGDGSNDAAAIRAATVGIGVVAHGSDPARVAADL VLVDGRIESLLPAILEGRQLWQRVQAAVSVLLGGNAGEVAFAIIGSAITGTSPLNTRQLLLVNMLTDALP AAALAVSKPSDPVTPATRGPDQRELWRAVGIRGATTAAAATVAWVMAGFTGLPRRASTVALVALVAAQLG QTLVDSHAWLVVLTALGSLAALATLISIPVVSQLLGCTPLDPLGWAQATAAATAATVAVAVLNRVLTGRD KSGQPNPQPPETDALSRDASPGAPPGPRRRRRATARRKAPVKAPSATRQTTKPKGPPAHRSSSTYPRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0425c | ctpH | - | 100% (1539) | POSSIBLE METAL CATION TRANSPORTING P-TYPE ATPASE CTPH |
| M. tuberculosis H37Rv | Rv0107c | ctpI | 0.0 | 36.81% (1584) | cation-transporter ATPase I |
| M. tuberculosis H37Rv | Rv1997 | ctpF | 3e-79 | 29.75% (864) | metal cation transporter P-type ATPase A CtpF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0433c | ctpH | 0.0 | 99.87% (1539) | metal cation transporting P-type ATPase CtpH |
| M. gilvum PYR-GCK | Mflv_0956 | - | 1e-76 | 29.21% (914) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
| M. leprae Br4923 | MLBr_02671 | - | 0.0 | 37.76% (1528) | putative cation transport ATPase |
| M. abscessus ATCC 19977 | MAB_0962 | - | 1e-51 | 26.49% (838) | cation-transporting ATPase E |
| M. marinum M | MMAR_0740 | ctpH | 0.0 | 72.33% (1547) | metal cation transporting p-type ATPase CtpH |
| M. avium 104 | MAV_5219 | - | 0.0 | 36.78% (1626) | ATPase, P-type (transporting), HAD superfamily protein, subfamily |
| M. smegmatis MC2 155 | MSMEG_3926 | - | 2e-81 | 30.47% (850) | cation-transporting ATPase Pma1 |
| M. thermoresistible (build 8) | TH_2876 | - | 0.0 | 44.25% (1417) | PUTATIVE ATPase, P-type (transporting), HAD superfamily, |
| M. ulcerans Agy99 | MUL_4826 | ctpI | 0.0 | 38.45% (1524) | cation-transporter ATPase I CtpI |
| M. vanbaalenii PYR-1 | Mvan_1651 | - | 0.0 | 47.00% (1468) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv ---------------MPVRAVATGFRATATLTGASITAATAVSATLAKTG
Mb0433c|M.bovis_AF2122/97 ---------------MPVRAVATGFRATATLTGASITAATAVSATLAKTG
MMAR_0740|M.marinum_M --MSIATSIKG---ALPLRALATGIQATSAMATASVMTTAAVAATLGRTT
TH_2876|M.thermoresistible__bu --MGVLRSTVGGLIGASLRTLQVAAGTALLAGDTVIGAGRTVAGTVADLA
Mvan_1651|M.vanbaalenii_PYR-1 -----------------------------MVTDVASGAASTAR-AAAGMV
MAV_5219|M.avium_104 -----------------------MVRAGVSTAAGAAGALQTLASPVAELA
MUL_4826|M.ulcerans_Agy99 MKIPGVVNPVANLVAGVTGGAVQMVRAGVQTAADAAGVLQTLASPVVELA
MLBr_02671|M.leprae_Br4923 MKIPHVTDPVSNMVG----GMAQVVRASTHAATGAVNTMQMLASPVAEFA
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv ---VGTGMKVAIIPLRAGAKALSGELSRETLGRNCWRGERRAWIEVRGLR
Mb0433c|M.bovis_AF2122/97 ---VGTGMKVAIIPLRAGAKALSGELSRETLGRNCWRGERRAWIEVRGLR
MMAR_0740|M.marinum_M GSVTKACLEFGAAPLREGAKALSGELSPETLTRHCWRGAGRAWIEVRGLN
TH_2876|M.thermoresistible__bu ADVATGAESTAHTTLGLVVEALGGPPARRTS-----RNDSRHWIEVCGLS
Mvan_1651|M.vanbaalenii_PYR-1 QDAAAGAPAAVQTAAAITTEALGGHPVKRSS-----RLNSHHWIEICGLS
MAV_5219|M.avium_104 GPVIQSMAQTTGRAIGLDGSADGAP-AIVPPVR--WHSGRRVHLDLDPLL
MUL_4826|M.ulcerans_Agy99 GPVVQSVAQTTNRAIGRNGAADGAPDGVTPPLR--WHSGRRVHFDLDPLL
MLBr_02671|M.leprae_Br4923 WPVVQSVAKSTGRALGTGHSPNFAN-RVDPPVR--WHNGQRVHLDLDPLL
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv -SGGDDELGRVVLNAIQAHPGVGSASLNYPLSRVVVAIDDPDTSLRELCR
Mb0433c|M.bovis_AF2122/97 -SGGDDELGRVVLNAIQAHPGVGSASLNYPLSRVVVAIDDPDTSLRELCR
MMAR_0740|M.marinum_M -DTPDGELARMVREAMRTHPGIASVRINYPLSRVVVDID-AATSLPQLCR
TH_2876|M.thermoresistible__bu -GPDADAIAEEVVSALRAVPGVTDVAINHSMARAVVTVE-TGVPAADLTA
Mvan_1651|M.vanbaalenii_PYR-1 -GPDADAIADEVLAAVHAVAGVRHAEINRSVARVIVTTE-PEGPAENLAQ
MAV_5219|M.avium_104 PFPRWHEYAPAVEEPVRRIPGVAKAHVEGSLGRLVVELADDADNAAVLDE
MUL_4826|M.ulcerans_Agy99 PFPRWHEHAAVVEEPVRRIPGVAKAHVEGALGRLVVELEDGADSDTVLDE
MLBr_02671|M.leprae_Br4923 PFPRWHEYAAVVEEPVRRIPGVAKGHVEGSLGRLVIELDKNADSDVVLGK
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv IVDDAEKAERHRHPDQAADQLAQSPGSLPGDGVLLAVRAVTVAATAAGLG
Mb0433c|M.bovis_AF2122/97 IVDDAEKAERHRHPDQAADQLAQSPGSLPGDGVLLAVRAVTVAATAAGLG
MMAR_0740|M.marinum_M LVEDTEKRYRATQDTYRP----TPAISLPGDSVVLVNRAVTVATNAAGLG
TH_2876|M.thermoresistible__bu VVAEAERRART-----TEAG-RHRPHTLPWDDALLAARAVGAAAAAVGLG
Mvan_1651|M.vanbaalenii_PYR-1 VVADAERRVRT-----GPCGDRHRPLTLPGDDALLAARTLGALAAVAGFG
MAV_5219|M.avium_104 VRSTVASVAADISWSKAEAAPPSAPFADPGNPLAILVPLTAAALDLVAMG
MUL_4826|M.ulcerans_Agy99 VCDTAATVAADIFLSGSASSPNSAPFADPGNPLAVLVPLTAAALDLAALG
MLBr_02671|M.leprae_Br4923 VRDVVIALAADLALTGARSAPKVAPFADPGNPLAILMPLTAAVMDLVALS
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv LALGGRALRWPRFPLVIEAAVAAVDHQPLLRRLLEDRIGTEATATVLELA
Mb0433c|M.bovis_AF2122/97 LALGGRALRWPRFPLVIEAAVAAVDHQPLLRRLLEDRIGTAATATVLELA
MMAR_0740|M.marinum_M LALTGRALRWPRVPITLLAGVVAVDYQPRLRSLLEDRIGGPATDTVMTLA
TH_2876|M.thermoresistible__bu LSVTGNVLRFRGLPDFLSAIPTLADHNPGIHRQFERRLGREGTDLLFSLL
Mvan_1651|M.vanbaalenii_PYR-1 LSVTGNALRVPRVMELLAVVPTMAANVPQLRRQFEHRLGRDSTDLLLSLM
MAV_5219|M.avium_104 AAVTGWVTRLPAAPQTTRAAAALINHQPRMVSILEARLGRVGTDIALAAT
MUL_4826|M.ulcerans_Agy99 AAVTGWVIRLPAAPQTTRAAAALINHQPRMVSLLESRLGRVGTDIALAAT
MLBr_02671|M.leprae_Br4923 AAVTGWVTRLPAVPQTIRAAAALVNHQPRMVSLLESRLGRVGTDIALSIT
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv MAAAHTVTLSPAALSVDLTIQALKAAECRAGARAWRRHEPQLALHADE--
Mb0433c|M.bovis_AF2122/97 MAAAHTVTLSPAALSVDLTIQALKAAECRAGARAWRRHEPQLALHADE--
MMAR_0740|M.marinum_M VAAAETLTQAPTSLSVGLAMQTLKAAEARAGALAWQHHEPELAQYAEQ--
TH_2876|M.thermoresistible__bu TSASAAMTVSPTSAAAEMATRTMMVVEAVHTRRAWRRHEPRLVRHRPS--
Mvan_1651|M.vanbaalenii_PYR-1 NAAASALTASPTSAAAEAATRTLLAAEAWDARVAWRRHEPRLAAYPPE--
MAV_5219|M.avium_104 TAAAHGLTQSFGTPLLDLTQRTLQISEAAAHRRVWRDREPQLASPDRPQA
MUL_4826|M.ulcerans_Agy99 TAAANGLTQAVSTPLLDLVQRGLQISEATAHRRVWRDREPALASPGRPQA
MLBr_02671|M.leprae_Br4923 TAAASGLTQAVGTPLLDLACRGLQLSEAAAHQRVWRDREPQLASPKRPQA
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv ---------------------------------PADQPQSLWPRPARSTQ
Mb0433c|M.bovis_AF2122/97 ---------------------------------PADQPQSLWPRPARSTQ
MMAR_0740|M.marinum_M ---------------------------------PATSAPYTAPRPAP-AR
TH_2876|M.thermoresistible__bu ---------------------------------SRRPHRGTLEFGAG---
Mvan_1651|M.vanbaalenii_PYR-1 ---------------------------------GGFPDRGTLEWDYG---
MAV_5219|M.avium_104 PVVPVISSA--KSEVPRHSWAAAAAGEASHVVVGGTIDAAMDKAKGSMAG
MUL_4826|M.ulcerans_Agy99 PVVPVISSAGVQAQEPRHSWAAAAAGEASHVMVGGSIDAAIDTAKGSMAG
MLBr_02671|M.leprae_Br4923 PVVPVISSAGEKSHAAGHNWTAAASNEASHLVVGGSIDAAIDTAKGSMKG
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv PVQRSVARFALIQALSAVLVGAGTRDADMAATATLVATPKASRTTPEAFA
Mb0433c|M.bovis_AF2122/97 PVQRSVARFALIQALSAVLVGAGTRDADMAATATLVATPKASRTTPEAFA
MMAR_0740|M.marinum_M AAERNADRFAHIQTISAGLVGLATRNMDMAATAALVATPKASRTTPEAFA
TH_2876|M.thermoresistible__bu AGERYADRAVRMGVTAAAVVGAVSRNPTIGGAAALVTAPKPSRAAREAFG
Mvan_1651|M.vanbaalenii_PYR-1 PSERYAERIGEAGLAAATIIGAVTRNPTIAASAALVTAPKPSRAARDAFG
MAV_5219|M.avium_104 PVESYVDSAANGSLIAAVSALVAGGGTEDAAAAIEAGVPRAAHMGRQAFA
MUL_4826|M.ulcerans_Agy99 PVESYVNSAANGALIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQAFA
MLBr_02671|M.leprae_Br4923 PVESYVDSAANGSLIAAASALLAGGGTEDAAGAILAGVPRAAHMGQQAFA
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv AALGQGLADQHAVLPLRPESLRRLDRVDAIVIDPRVLCTDDLRVARIRGC
Mb0433c|M.bovis_AF2122/97 AALGQGLADQHAVLPLRPESLRRLDRVDAIVIDPRVLCTDDLRVARIRGC
MMAR_0740|M.marinum_M AALGQGLAQRHGVLSMRPDCLRRLDEVDAVVIDPRVLCTNKLRVARIRGA
TH_2876|M.thermoresistible__bu CAMTRGLITHHDALVVRPRALRALDRVDAVVIDPRVLYTDQLAVTRIVGV
Mvan_1651|M.vanbaalenii_PYR-1 AAMTRGLTNQHDVVVVRPRALRHLDRLDAIVIDPRALYTDKLTVTRIVGV
MAV_5219|M.avium_104 AVLGRGLANS-GQLVLDPGALRRLDRVKVVVIDGAALRGDHRAVLRVRGE
MUL_4826|M.ulcerans_Agy99 AVLGRGLASE-GQLVLDPGALRRLDRVQVVVIDGAALRGDHRSVLRAQGD
MLBr_02671|M.leprae_Br4923 ATLGRGLANA-GQLVLDPGALRRLDQVKVVVIDGAALRGDHRAVLLARGN
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv GADELSTAWNRAQLVLTESGLRPG--------------WHRVPGVSASGS
Mb0433c|M.bovis_AF2122/97 GADELSTAWNRAQLVLTESGLRPG--------------WHRVPGVSASGS
MMAR_0740|M.marinum_M DEDQLSAAWNRAQLLLERDDLSPG--------------WHAVPENPDSTG
TH_2876|M.thermoresistible__bu TNSDRDRAWRAVQRALDRGGLTPG--------------WHPLSSIAGAP-
Mvan_1651|M.vanbaalenii_PYR-1 TNSRRTHAWEAVRAALDADSMSPG--------------WHKLSTIPGAG-
MAV_5219|M.avium_104 APGWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPSQGPSAMPA
MUL_4826|M.ulcerans_Agy99 EPGWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPLRGPSATPA
MLBr_02671|M.leprae_Br4923 TPGWDDDRVYEVTDALLHGERAPEPDPDESPATGARLRWVPLQGPSATPV
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv ------------DSAVEALFRPMHDRLASAVVAEAHRTGADLVSVDVDAL
Mb0433c|M.bovis_AF2122/97 ------------DSAVEALFRPMHDRLASAVVAEAHRTGADLVSVDVDAL
MMAR_0740|M.marinum_M ------------VFEAEALFLPAHDPLASAVVAEAHRTGADLVSVDDDSL
TH_2876|M.thermoresistible__bu -------------ASGRILISPVRDQFAAAVVTEAHRCGRRVLSLDDDGL
Mvan_1651|M.vanbaalenii_PYR-1 -------------RAGKALVSPVRDPLANAVVTEARRTKPRVVSIADDGL
MAV_5219|M.avium_104 QGLESADLIVDGDRVGRVDVGWEVDPYAIPLFQTAHRTGARVVLRHVAGT
MUL_4826|M.ulcerans_Agy99 QGLEHADLVVDGQTVGNVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGT
MLBr_02671|M.leprae_Br4923 QGREHADLVVNGECVGGVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGT
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv GELRPVFDDIRPLDDGASGSLDEALARAVAELRQAGRTVAVLSSVGKQAL
Mb0433c|M.bovis_AF2122/97 GELRPVFDDIRPLDDGASGSLDEALARAVAELRQAGRTVAVLSSVGKQAL
MMAR_0740|M.marinum_M GELRPAFDDIRPLRH---GSIDDALTDAVVALRQAGRTVALLSSQ-SRAI
TH_2876|M.thermoresistible__bu RSLARGFDKLYPLGD----SVDESLAAAVAEAKADGATVALFTSPAMTAP
Mvan_1651|M.vanbaalenii_PYR-1 RSLAQGFDRLYPVDG----SIDEALAAAVDELKADGATVALLTTPDLSAN
MAV_5219|M.avium_104 EDLTASVGATHPPGTPLLNVVRELRADRGPVLLITALHRDFASTDTLAAL
MUL_4826|M.ulcerans_Agy99 EDLSASVGSTHPPGTPLLNLVRELRTDPGPVLLITALHRDFASTDTLAAL
MLBr_02671|M.leprae_Br4923 EDLSASVGATHPPGTPLLKLVRELRTDRGPVLLITAVHRDFASTDTLAAL
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv SAADVALGVLPPPGAGAPPWYADVLLP-DLGAAWRVLHAIPAARAARQRG
Mb0433c|M.bovis_AF2122/97 SAADVALGVLPPPGAGAPPWYADVLLP-DLGAAWRVLHAIPAARAARQRG
MMAR_0740|M.marinum_M SLADVALGVLPRTADAVPPWYADVLLP-DLGAAWRIMHAIPAAKAARRRG
TH_2876|M.thermoresistible__bu HAADITIGLSPD--GHPPPWGADVFVP-DLVSMWRILRALPAARSATTKG
Mvan_1651|M.vanbaalenii_PYR-1 QDADLTIGLERP--GWPPPWGADVFVP-DLLSVWRILHSLPTARAVTARG
MAV_5219|M.avium_104 AIADVGVALDDP--RAATAWTADIITGTDLADAVRILSAIPVARSASESA
MUL_4826|M.ulcerans_Agy99 AIADIGVALDDP--RAATPWTADIITGTDLAAAVRILSAIPVARASSVSS
MLBr_02671|M.leprae_Br4923 AIADVGVALDDP--HAATPWTADIITGTDLAAAVRILSALPVARSASESS
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Rv0425c|M.tuberculosis_H37Rv NEISGGASALGALLMLPGVR----------GLGPGPVTTGAAAGLLSGYL
Mb0433c|M.bovis_AF2122/97 NEISGGASALGALLMLPGVR----------GLGPGPVTTGAAAGLLSGYL
MMAR_0740|M.marinum_M IEISGGASALGALLMVPGVR----------GLGPGPVTTGAGAGLLSGYL
TH_2876|M.thermoresistible__bu VRLSASSTAIGALMLIPGVT----------GNGPDSVNVGVAAGLWSGFR
Mvan_1651|M.vanbaalenii_PYR-1 VRLSVSATTLGALMLIPGVP----------GSGPESVSVGVVGALWSGFT
MAV_5219|M.avium_104 VHLAQGGTTLAGLLLVTGEQ-EKGASPVSFRRWLNPVNAAAATALVAGTF
MUL_4826|M.ulcerans_Agy99 VHLAQGGTTLAGLLLVTGEQ-ARTTNPASFRRWLNPVNTAAATALLSGSW
MLBr_02671|M.leprae_Br4923 VHLAQGGTTLAGLLLITASAGSKSASPITLRRWFSPVNAAAATALVTGVV
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK ---------------MSDWHARSVREVTDALD-------TDVTAGLTSEA
MSMEG_3926|M.smegmatis_MC2_155 ---MRRPADAGGNSNENNWHTMQPDEVLDALG-------ASR-SGLTDSE
Rv0425c|M.tuberculosis_H37Rv LARKVVDAQAPRPAPAHEWHAMSVEQVRKALP-SPDEQAPAKAPPSPYPA
Mb0433c|M.bovis_AF2122/97 LARKVVDAQAPRPAPAHEWHAMSVEQVRKALP-SPDEQAPAKAPPSPYPA
MMAR_0740|M.marinum_M LARKVVGARPPRPAAFHEWHAMSVEQVQKLLP-PTDTSPQPGAPHSTLAT
TH_2876|M.thermoresistible__bu TATKVFDDSPPEPEPSHDWHALPADEVRRLLPRPGDGDRQPPAGRDPALM
Mvan_1651|M.vanbaalenii_PYR-1 AGSKVFRDPPPEPESVHDWHAMPVAEVERLLPRPPD--EEPDVSTGLTDL
MAV_5219|M.avium_104 SATRVLRLPDPTPQPLTAWHALDPEIVYSRLA----GGARPLAVET-EPS
MUL_4826|M.ulcerans_Agy99 SAATVLRLPDPTPQPLTAWHALDPEIVYARLA----GGARPMAVDPGTPT
MLBr_02671|M.leprae_Br4923 SASKVLRLPDPTPQPLTAWHALDPEIVYSRLA----GVTQPLAVEPGTPD
MAB_0962|M.abscessus_ATCC_1997 ---------------MATIEGLTISGLT-----------AAEVAERVAQG
. :
Mflv_0956|M.gilvum_PYR-GCK AEERRHRHGPNQLTEAAAVP------VWRKVLRLLADKMTLVLLVAAAVS
MSMEG_3926|M.smegmatis_MC2_155 VERRRAVHGWNRLAAVRKQS------ALVPFIRQFHNVLIYVMSCAAIVT
Rv0425c|M.tuberculosis_H37Rv RALAGGLHTAKRGAQITQAPLNALWQLTKAMRAELSDPLTPMLALGAMAS
Mb0433c|M.bovis_AF2122/97 RALAGGLHTAKRGAQITQAPLNALWQLTKAVRAELSDPLTPMLALGAMAS
MMAR_0740|M.marinum_M RALSSGAHAAKRGAELGAEPMQAIGQFLGAVRAELSDPLTPMLALGATAS
TH_2876|M.thermoresistible__bu RPVRAAAAAMTWFWQLTRD-------FTAEMRSNLADPITPLLATGAVAS
Mvan_1651|M.vanbaalenii_PYR-1 PPLRALSQAGTWSWHLTRD-------FVAEMRTNLSDPITPLLATGAVAS
MAV_5219|M.avium_104 WRRRLDDLSYSPALAPLRAPLQNVLRLASATRTELADPLTPILAVGAAAS
MUL_4826|M.ulcerans_Agy99 WRRLLDDLSYEPLVSPLRGPAHTLAQLAAATRHELADPLTPILAVGAAAS
MLBr_02671|M.leprae_Br4923 WRRRLDDLSYTRALSPLRKPVTKLARLASATRQEFADPLTPILAVGAAAS
MAB_0962|M.abscessus_ATCC_1997 KTNDVPSRAARSVSDIVRAN------VFTRINAILGVLLIIVLSTGSIIN
: : :: .: .
Mflv_0956|M.gilvum_PYR-GCK AVVSREWETPVVIMLVVTLNTVLNYVQEARAENSLQALRDMSISYSR---
MSMEG_3926|M.smegmatis_MC2_155 AVLQ-HWVDAAVLFAAVLINVVIAYVQEGRAQAALDAIRAMMSPHAT---
Rv0425c|M.tuberculosis_H37Rv AVLG-SPVDAVMVGSVLTGNSILAASQRLRAESRLNRLLAQQIPPARKVL
Mb0433c|M.bovis_AF2122/97 AVLG-SPVDAVMVGSVLTGNSILAASQRLRAESRLNRLLAQQIPPARKVL
MMAR_0740|M.marinum_M AVLG-SPVDAVMVGSVLTGNSILAATQRLRAESRLNRLLALQIPPARKVV
TH_2876|M.thermoresistible__bu ALLG-SPLDAALVGGVLLLNAALSAQQQLHAERILRRLMAVQEPSARRRV
Mvan_1651|M.vanbaalenii_PYR-1 ALLG-SPLDAALVGGVLLANAALSAEQQLHAERILQRLMAVEEPLARRRV
MAV_5219|M.avium_104 AIVG-SNIDALLVAGVMTVNAITGGAQRLRAESAAAELFAEQDQMVRRVV
MUL_4826|M.ulcerans_Agy99 AIVG-SNVDALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQMVRRVV
MLBr_02671|M.leprae_Br4923 AIVG-SNIDALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVV
MAB_0962|M.abscessus_ATCC_1997 GAFG----------LLIIANSAVGIIQELRAKQILDKLAIVGQTRPL---
. . : * *. :*: :
Mflv_0956|M.gilvum_PYR-GCK ----------------VRRDGGEHRLPRTELVPGDVVLLEAGDAVPADGR
MSMEG_3926|M.smegmatis_MC2_155 ----------------VTRNGRTLDVEAVELVPGDVVQLAAGDRIPADLR
Rv0425c|M.tuberculosis_H37Rv AG--------------ADDQPRYIEVRAEELRPGDIIEVRTHEVVPADAR
Mb0433c|M.bovis_AF2122/97 AG--------------ADDQPRYIEVRAEELRPGDIIEVRTHEVVPADAR
MMAR_0740|M.marinum_M TG--------------QDGQPGYVDVVAEQLRPGDVIEVRTHEVVPADAR
TH_2876|M.thermoresistible__bu RMATATGTGATGTEATPVEAGPIEEVPANRLRPGDVIEVRVGDVVPADAR
Mvan_1651|M.vanbaalenii_PYR-1 G---------------PLDQRRNERVSASRLRPGDIIEVHADEVVPADAR
MAV_5219|M.avium_104 VPAVATTRR---RLEAARHATRTATVSAKSLRPGDVIDLAAPEVVPADAR
MUL_4826|M.ulcerans_Agy99 VPAVATTRR---RLEAARHATRTATVSAKSLRVGDVIDLAAPEVVPADAR
MLBr_02671|M.leprae_Br4923 VPAVATTRR---RLEAAQHATRTVTVSAKSLRAGDVIDLAAPEVVPADAR
MAB_0962|M.abscessus_ATCC_1997 ----------------VRRDGAATALAPNEVVLDDIIELGPGDQIVVDGE
: : .*:: : : : .* .
Mflv_0956|M.gilvum_PYR-GCK IVSAARLQVAESALTGESAPVDKAVDGLDDTDLPLGDRTNMLYMNTEVTR
MSMEG_3926|M.smegmatis_MC2_155 LIGVDGLQVDEAPLTGESAPVWKTIG-VDDEDTSLPDRRSMAYSGTLAIH
Rv0425c|M.tuberculosis_H37Rv VIEEVDVEVDESALTGESLSVTKQVE--PTPGVDLIERRCMLYAGTTVVS
Mb0433c|M.bovis_AF2122/97 VIEEVDVEVDESALTGESLSVTKQVE--PTPGVDLIERRCMLYAGTTVVS
MMAR_0740|M.marinum_M VIDETDVEVDESALTGESLSVTKQVE--PTPGADLADRSCMLYAGTTVVA
TH_2876|M.thermoresistible__bu IMAASNVEVDESSLTGESLPVPKTAA--ATPGAPLAERSGMLYAGTTMVA
Mvan_1651|M.vanbaalenii_PYR-1 LIEATNIEVDESSLTGESLPVPKQTD--PTPGAPLAERACMLYAGSTLVA
MAV_5219|M.avium_104 LLEAEDLEVDESLLTGESLPVDKQVE--PVA-VNDPDRASMLFEGSTIVA
MUL_4826|M.ulcerans_Agy99 LLVAEDLEVDESLLTGESLPVDKQVD--PVA-VNDADRASMLFEGSTIVA
MLBr_02671|M.leprae_Br4923 VLVAEDLEVDESLLTGESLPVDKRVD--PVA-INDADRASMLFEGSAIVA
MAB_0962|M.abscessus_ATCC_1997 VIEESALEIDESLLTGEADAIEKTIG-------------SQVLSGSFVVA
:: ::: *: ****: .: * .:
Mflv_0956|M.gilvum_PYR-GCK GRATMVVTATGMDTEVGAIATMLGTAGVSRTPLQQRIDNLAQMLTVVALL
MSMEG_3926|M.smegmatis_MC2_155 GQATGVVVGTGAQTELGRINHLLTGVAPTATPLLRQISRFGRVLAVVILL
Rv0425c|M.tuberculosis_H37Rv GTAVAVVTAVGPDTQERRAAELVSGDLSSVG-LQHQLSRLTNQAWPVSMT
Mb0433c|M.bovis_AF2122/97 GTAVAVVTAVGPDTQERRAAELVSGDLSSVG-LQHQLSRLTNQAWPVSMT
MMAR_0740|M.marinum_M GTAVAVVTAVGADTQERRAADLVSGDLSNVG-LQHQLSQLTNRAWPVSMT
TH_2876|M.thermoresistible__bu GTAVAVVTAVGPRTEVRRALAMAAERPGEIG-LQRQLAHITKRALPFSVS
Mvan_1651|M.vanbaalenii_PYR-1 GTAVAVVTTVGSRTEMRRALAMAPDKSREIG-LQRQLSRITKRALPFSVG
MAV_5219|M.avium_104 GHARAIVVATGVGTAAHRAISAVADVETAAG-VQARLRELTSKVLPLTLA
MUL_4826|M.ulcerans_Agy99 GRARAIVVATGAGTAAHRAISAVADVETSAG-VQARLRELTSKVLPLTLA
MLBr_02671|M.leprae_Br4923 GHARAIVVATGVGTAAHRAISAVADVEVSAG-VQARLRELTSKVLPLTLA
MAB_0962|M.abscessus_ATCC_1997 GSGAYRATKVGREAYAAKLAEEASKFTLVHSELRNGINKILQFITYLLLP
* . .. .* : : : .: . :
Mflv_0956|M.gilvum_PYR-GCK VVIVVTVLG-LLRGDTWTELLLTAVSLAVATIPEGLTAVVAFTLAMGASR
MSMEG_3926|M.smegmatis_MC2_155 LSAATYALGVIWRGETLTEMFMMTVALAASAIPEGLPAIMTVTLAIGVQR
Rv0425c|M.tuberculosis_H37Rv GGALVTGLG-LLRRRGLRQAVASGIAVTVAAVPEGMPLVATLAQQASARR
Mb0433c|M.bovis_AF2122/97 GGALVTGLG-LLRRRGLRQAVASGIAVTVAAVPEGMPLVATLAQQASARR
MMAR_0740|M.marinum_M GGAVVTGLG-LLRRQGLRQAVASGIAVTVAAVPEGMPLVATLAQQASARR
TH_2876|M.thermoresistible__bu SGALVGLLS-VLRGTPIRAAVGSAVSLIVAAVPEGLPLVATLAQLASARR
Mvan_1651|M.vanbaalenii_PYR-1 GGALVGLLS-LARGTPLREAVGSSVALTVAAVPEGLPLVATLAQLASARR
MAV_5219|M.avium_104 GGAAVSTLA-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLSAAQR
MUL_4826|M.ulcerans_Agy99 GGASVSVLA-LMRRATLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQR
MLBr_02671|M.leprae_Br4923 GGAAVTGLA-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQR
MAB_0962|M.abscessus_ATCC_1997 AGALIIYTQLFTTDDSWQESVLRMVGALVPMVPEGLVLMTSIAFAVGVIR
. . :. .. :***: : :.: .. *
Mflv_0956|M.gilvum_PYR-GCK LARRGAIIKQLSAVETLGSTADIATDKTGTLTLNEMTVRRLLLPGREFRV
MSMEG_3926|M.smegmatis_MC2_155 MSRRRAIVCRLPAVEALGSVTVICTDKTGTLTSNEMTVQRVVCGGHDIDV
Rv0425c|M.tuberculosis_H37Rv LSHFGALVRIPRSVEALGRVDMVCFDKTGTLSENRLRVAQVRP-------
Mb0433c|M.bovis_AF2122/97 LSHFGALVRIPRSVEALGRVDMVCFDKTGTLSENRLRVAQVRP-------
MMAR_0740|M.marinum_M LTHFGALVRIPRSVEALGRVDMVCFDKTGTLSENRLRVAQVHP-------
TH_2876|M.thermoresistible__bu LSGESILIRNPNSIEALARLQVVCFDKTGTLSENRLQVKAVHP-------
Mvan_1651|M.vanbaalenii_PYR-1 LTGESVLIRNAQSIEAMARLQVVCFDKTGTLSENRLRVKAVRP-------
MAV_5219|M.avium_104 LTARGALVRAPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPDDV----
MUL_4826|M.ulcerans_Agy99 LTAHGALVRAPRTIEALGRVDTVCFDKTGTLTENRLRVVCAIPSST----
MLBr_02671|M.leprae_Br4923 LTAKGALVRSPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPNTR----
MAB_0962|M.abscessus_ATCC_1997 LGRRQCLVQELPAIEGLARVDTVCADKTGTLTENGMRLADVHFP------
: :: ::* :. :. ******: * : :
Mflv_0956|M.gilvum_PYR-GCK SGEGYSTDGKILVS----DGRPLPDLTAPLLAMALCSDASVREG----SL
MSMEG_3926|M.smegmatis_MC2_155 GGVGYAPVGDFSIDGRVIDPSRYPALMEALLAASLCNDASLDVEDEVWVI
Rv0425c|M.tuberculosis_H37Rv --------------------------VAGHSREEVLRCAAHAAPASNG-P
Mb0433c|M.bovis_AF2122/97 --------------------------VAGHSREEVLRCAAHAAPASNG-P
MMAR_0740|M.marinum_M --------------------------GPGFSDHDVLRCAVHAAPATNGGP
TH_2876|M.thermoresistible__bu --------------------------MRGRTETEVLEAALSTTFAEPGHR
Mvan_1651|M.vanbaalenii_PYR-1 --------------------------IDGFTEEQALDAALSTIFVRAGHR
MAV_5219|M.avium_104 -----------------NPHDPFPELTAPQSAELVRAAARASARPQEGQG
MUL_4826|M.ulcerans_Agy99 -----------------SPLDPFIDSADPRSTEVLRAAARATTQPHDGQG
MLBr_02671|M.leprae_Br4923 -----------------MPHDPLPDITDPHSAAVLRDAARASTQPHDGQG
MAB_0962|M.abscessus_ATCC_1997 ------------------------------DRDGDEDALAVLAQLAADDP
Mflv_0956|M.gilvum_PYR-GCK VGDPTEGALVVLAEKGGVDVTGARAAIP--RLAEVPFDSEYKYMATFCAR
MSMEG_3926|M.smegmatis_MC2_155 TGDPTEAALLVVAKKAGLDHDRETVSHP--RVATVPFASENRIMGTLHS-
Rv0425c|M.tuberculosis_H37Rv QVHATDVAIVQAAAAAAASGTDGAEPGAAEPAAHLPFRSGRSFSASVSGT
Mb0433c|M.bovis_AF2122/97 QVHATDVAIVQAAAAAAASGTDGAEPGAAEPAAHLPFRSGRSFSASVSGT
MMAR_0740|M.marinum_M QVHATDVAIVAAAPPELAAELDRSD-------AHLPFRSGRSFSASVSDT
TH_2876|M.thermoresistible__bu AHHATDEAIIRAVNG---AAIAAPAQRD----GFLPFQAGRPYAAAVRGT
Mvan_1651|M.vanbaalenii_PYR-1 AHHATDDAIRRAVHGDEDAADTTEIERD----AFLPFQAGRPFAAAIVGT
MAV_5219|M.avium_104 HAHATDEAILTAASSLNGQRDSDWS-----MIAEVPFESSRGFAAAIGTV
MUL_4826|M.ulcerans_Agy99 HAHATDEAIIVAANSLEGLNDSAWT-----VIAEVPFESSRGYAASIGTT
MLBr_02671|M.leprae_Br4923 HTHATDEAILTAASSLNSHTDSTWS-----LIAEVPFESSRGYAAAIGIT
MAB_0962|M.abscessus_ATCC_1997 RPNASIAAIAEAYDTPPGWETTAIA----------PFSSAKKWSGASYGE
..: *: ** : .:
Mflv_0956|M.gilvum_PYR-GCK SDLDGSGGH--RCFVKGAPGVLLEHAGSVLGEDGPRPIDPGYRQRIRERV
MSMEG_3926|M.smegmatis_MC2_155 -DVDRTP----LIVVKGAPERVLDICDSQRSPHGEEPLDRLYWQRMAA--
Rv0425c|M.tuberculosis_H37Rv E-----------LTVKGAPEVVLAACEGIG-------------SSMDDAV
Mb0433c|M.bovis_AF2122/97 E-----------LTVKGAPEVVLAACEGIG-------------SSMDDAV
MMAR_0740|M.marinum_M E-----------LSIKGAPEVVLAACGANG-------------PSIDRQV
TH_2876|M.thermoresistible__bu R-----------LTIKGAPEVLASALARGD-------------SALTRRV
Mvan_1651|M.vanbaalenii_PYR-1 R-----------LTIKGAPEVLASALAQAN-------------GPAVAAI
MAV_5219|M.avium_104 GNANGNPSDTPVLILKGAPEVILPRCRFADPEADQ--------QRAEAVV
MUL_4826|M.ulcerans_Agy99 GTSNGHPT----LMLKGAPETILPRCRFADPDADL--------EHAEALV
MLBr_02671|M.leprae_Br4923 G--NGKAP---MLMLKGAPEKILPRCRFADPEADV--------AHAESLV
MAB_0962|M.abscessus_ATCC_1997 HG----------NWVIGAPDVLLDPA-----------------DAIATAA
: *** :
Mflv_0956|M.gilvum_PYR-GCK EQLASEGLRTLMIAGRDIDHDLPADPDGLQT-----LVDDLTVYAVVGIV
MSMEG_3926|M.smegmatis_MC2_155 -TTAAQGLRVLAIARR-CGAPRNAGTLDIAD-----LDSGFTMLGLVGII
Rv0425c|M.tuberculosis_H37Rv AELAANGLRVIAVAHRQLTAQQAQSVVDDPDEIARLCRDELSLVGFLGLS
Mb0433c|M.bovis_AF2122/97 AELAANGLRVIAVAHRQLTAQQAQSVVDDPDEIARLCRDELSLVGFLGLS
MMAR_0740|M.marinum_M AELAADGLRVIAVARRELSPQQARTVVDDPDAIADFCHDGLALVGFLGLS
TH_2876|M.thermoresistible__bu EAMAAQGLRVLAVAGRELSPEQAAAAVADPAVFTELCGSGLSLFGLIGLA
Mvan_1651|M.vanbaalenii_PYR-1 DDMAAKGLRVIAVAERQLTPEQAAAAAADAAAFEELCRSDLTPIGLLGLA
MAV_5219|M.avium_104 RGLAEQGLRVLAVAQRGWKHDTDDDD-TDADAVDAAAHN-LELLGYVGLA
MUL_4826|M.ulcerans_Agy99 HSLAERGLRVLAVAKRPWEHDTADDDDTDADAVDAAAHD-LELLGYVGLA
MLBr_02671|M.leprae_Br4923 RHLAEQGLRVLAVAQCSWGHDTTDDNDTDADAVDAAAHD-LELVGYIGLA
MAB_0962|M.abscessus_ATCC_1997 EEIGARGLRVLLLASAELSVDDAHAP------------GAVTPRALVVLE
. ***.: :* . . . : :
Mflv_0956|M.gilvum_PYR-GCK DPPRPEAGEAIATAHAAGITVHMITGDHLSTAAAVAHDLGIPG--AAASG
MSMEG_3926|M.smegmatis_MC2_155 DALRPEVAAAVRECHRAGIRVKMITGDHAATAREIGAQLGIGIGKPAVIG
Rv0425c|M.tuberculosis_H37Rv DTPRAQAAALLADLHEHDLDIRLITGDHPITAAAIAEELGMQVSPEQVIS
Mb0433c|M.bovis_AF2122/97 DTPRAQAAALLADLHEHDLDIRLITGDHPITAAAIAEELGMQVSPEQVIS
MMAR_0740|M.marinum_M DTPRPTAAGLLAELSGHGLDVRLITGDHPITAAAIAEELGLRVSAKQIIS
TH_2876|M.thermoresistible__bu DTPRPSARGVLADLTERGIGVRLITGDHPVTAAVTARELGLDVDGEQVIT
Mvan_1651|M.vanbaalenii_PYR-1 DTPRASAQDVLKELGNRGIGVRLITGDHPVTAMVIAGELGLDVTAEQVMT
MAV_5219|M.avium_104 DTARASARPLIEALLDAERDVVLITGDHPITARAIARQLGLPADAR-VVT
MUL_4826|M.ulcerans_Agy99 DTARPSARPLIEALVDAQRNVVLITGDHPITARAIARQLGLPEDVR-VVT
MLBr_02671|M.leprae_Br4923 DTARPSSRPLIEALVTAGRNVVLITGDHPITARAIAQQLGLRSDAR-VVN
MAB_0962|M.abscessus_ATCC_1997 QKIRPDARETLDYFASQHVSIKVISGDNAVSVSAVAQTLGLTG----AAV
: *. : : :*:**: :. . **:
Mflv_0956|M.gilvum_PYR-GCK -ADLDRLDDDTLREQSPSFGVLARVAPEHKIRLVKALQSRGHVVAMTGDG
MSMEG_3926|M.smegmatis_MC2_155 -SEIASLNDTDLQTVVQERDIFARASPEHKLRLVRALQAGGEVVAMTGDG
Rv0425c|M.tuberculosis_H37Rv GAEWDALSRKDQERAVAERVIFARMTPENKVQIVQTLEHSGRVCAMVGDG
Mb0433c|M.bovis_AF2122/97 GAEWDALSRKDQERAVAERVIFARMTPENKVQIVQTLEHSGRVCAMVGDG
MMAR_0740|M.marinum_M GAQWDALSRKDQERAVAERVIFARMTPENKVQIVQTLERVGRVCAMVGDG
TH_2876|M.thermoresistible__bu GAEWETLSAEERAAAVRSRSVFARMSPEHKIDVVQTLERNGVVTAMVGDG
Mvan_1651|M.vanbaalenii_PYR-1 GAEWEGLSAEERSEAVVSRIVYARMSPEHKIDVVQTLERIGMVTAMVGDG
MAV_5219|M.avium_104 GAELAGLDEDACAKLVADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDG
MUL_4826|M.ulcerans_Agy99 GAELIGLDEDACAKLAADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDG
MLBr_02671|M.leprae_Br4923 GTELIGLDEDACAELAADVQVFARVSPEQKVQIVAALQRCGQVTAMVGDG
MAB_0962|M.abscessus_ATCC_1997 DARTLPTDTDKLAATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDG
: . . .* *::* :* :*: * . **.***
Mflv_0956|M.gilvum_PYR-GCK VNDAPALKQADIGIAMGITGTDVSKGAANMILTDDNFGTIVAAVREGRGI
MSMEG_3926|M.smegmatis_MC2_155 VNDSPALKKADVGIAMGCRGTEAAKEAADMVLADDNFATIAAAVSEGRTV
Rv0425c|M.tuberculosis_H37Rv SNDAAAIRAATVGIGVVAHGSDPARVAADLVLVDGRIESLLPAILEGRQL
Mb0433c|M.bovis_AF2122/97 SNDAAAIRAATVGIGVVAHGSDPARVAADLVLVDGRIESLLPAILEGRQL
MMAR_0740|M.marinum_M SNDAAAIRAATVGIGVVAHGSDPASVAADMVLLDGRIESLLPSILEGREL
TH_2876|M.thermoresistible__bu ANDAAAIRAASVGVGVATRSSDPARTAADIVLLDGRIEALIDALDEGHHL
Mvan_1651|M.vanbaalenii_PYR-1 ANDAAAIRAASVGFGVASRGSDPARTAADVVLLDGRIEALLDALDEGKQL
MAV_5219|M.avium_104 ANDAAAIRMADVGIGVSGRGSSAARGAADIVLTDQDLSVLLDALVEGRSM
MUL_4826|M.ulcerans_Agy99 ANDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSM
MLBr_02671|M.leprae_Br4923 ANDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSM
MAB_0962|M.abscessus_ATCC_1997 VNDVLALKDADIGVAMG-AGSSASRAVAQIVLLDNKFATLPYVVAEGRRV
** *:: * :*..: .:. : .*:::* * : : : **: :
Mflv_0956|M.gilvum_PYR-GCK YANIIKFVKFQLTTAWGFVLIFLVCGSLGLAG-GAPFTALQILWVNIIMD
MSMEG_3926|M.smegmatis_MC2_155 YDNIRKFVLFMLPTNGGEALVVIAAILFQFT---LPLTPAQVLWINLVTS
Rv0425c|M.tuberculosis_H37Rv WQRVQAAVSVLLGGNAGEVAFAIIGSAITG---TSPLNTRQLLLVNMLTD
Mb0433c|M.bovis_AF2122/97 WQRVQAAVSVLLGGNAGEVAFAIIGSAITG---TSPLNTRQLLLVNMLTD
MMAR_0740|M.marinum_M WQRVQAAVSVLLGGNAGEVAFAIIGSAITG---TSPLNTRQLLLVNMLTD
TH_2876|M.thermoresistible__bu WRRVQSAVSMLLGGNSGEIAFALLTSLLTG---RSVLNARXXXTTAADAE
Mvan_1651|M.vanbaalenii_PYR-1 WRRVQSAVSMLLGGNTGEIAFALITSLLTG---RSVLNARQMLLVNMLTD
MAV_5219|M.avium_104 WAGVRDAVTILVGGNVGEVLFTIIGTAFGAG--RAPVGTRQLLLVNLLTD
MUL_4826|M.ulcerans_Agy99 WAGVRDAVTILVGGNVGEVLFTIIGTAFGAG--RAPVGTRQLLLVNLLTD
MLBr_02671|M.leprae_Br4923 WAGVRDAVTILVGGNVGEVVFTIIGTVFGAG--RAPVGTRQLLLVNLLTD
MAB_0962|M.abscessus_ATCC_1997 IGNIERVSNLFLTKTVYSVLLALTVGLAGLGSKIFHYGAVPFPFQPIHVT
: . : . : .
Mflv_0956|M.gilvum_PYR-GCK GPPALALGVDPTEPDVMHQKPRPP----------------------TERL
MSMEG_3926|M.smegmatis_MC2_155 STLGLALAFEPPEAGVMRRKPRAP----------------------SESL
Rv0425c|M.tuberculosis_H37Rv ALPAAALAVSKPSDPVTPATRGPD----------------------QREL
Mb0433c|M.bovis_AF2122/97 ALPAAALAVSKPSDPVTPATRGPD----------------------QREL
MMAR_0740|M.marinum_M ALPAAALAVSKPRGQTDPNARGPD----------------------QQAL
TH_2876|M.thermoresistible__bu PIPCKARAIP--SMVMSGATAHST----------------------DASM
Mvan_1651|M.vanbaalenii_PYR-1 ALPAAALAVS--RQTDTTGQVDLD----------------------EAAM
MAV_5219|M.avium_104 MFPALAVAVTSQYVEPDEAEYPSAADAEAARREHRRAVLTGPTPSLDAPL
MUL_4826|M.ulcerans_Agy99 MFPALAVAITSQYDDPEDDSDLSDEEIEEARRRRQRAVLTAPTPSLDAPL
MLBr_02671|M.leprae_Br4923 MFPALSIAVTSQYEEPGEDEYQTDEEADEARRTHQHEVLTGPTPSLDAPL
MAB_0962|M.abscessus_ATCC_1997 IAAWFTIGIPAFILSLAPNNERAQTG-------------------FVRRV
: .. :
Mflv_0956|M.gilvum_PYR-GCK LNRARLQRILVLGMVMTLGTVTVLMLADDLFPESAGDPLFATTLAFTTFV
MSMEG_3926|M.smegmatis_MC2_155 LSRHFAWRVLLVSVLMAGGALGMFLWE----LRSGTSVETARTMAVNAIV
Rv0425c|M.tuberculosis_H37Rv WRAVGIRG-----ATTAAAATVAWVMAGFTGLPRRA---------STVAL
Mb0433c|M.bovis_AF2122/97 WRAVGIRG-----ATTAAAATVAWVMAGFTGLPRRA---------STVAL
MMAR_0740|M.marinum_M WRAVGVRG-----TTTAAAATAAWMMAGVTGLPRRA---------STVGL
TH_2876|M.thermoresistible__bu CTAIPAISGRRRPNESDRGPTTSWPSASPTSVPVNVSCATDDDTFSSSAI
Mvan_1651|M.vanbaalenii_PYR-1 WRAIGVRG-----AATTVGATSAWAMASMTGTPQRA---------STVAL
MAV_5219|M.avium_104 MRQIVTRG-----AVTAAGATAAWAIGRWTPGTERR--------TATMGL
MUL_4826|M.ulcerans_Agy99 MRQIANRG-----VVTAAGATAAWAIGRWTPGTERR--------TATMGL
MLBr_02671|M.leprae_Br4923 MRQIVNRG-----VVTAAGATTAWAIGRWTPGTERR--------TATMGL
MAB_0962|M.abscessus_ATCC_1997 MLSAIPSG-----LTVGIATFLSYLLARQILHVSGN--------STQAST
..
Mflv_0956|M.gilvum_PYR-GCK FYQVFNLLNVRSDTGSAFSRQ-TFTNGAIWVS----------------LA
MSMEG_3926|M.smegmatis_MC2_155 AAEMFYLLNNRFLLEPVLNRIGLFGNKIAFAT----------------VV
Rv0425c|M.tuberculosis_H37Rv VA----LVAAQLGQTLVD-SHAWLVVLTALGS---------------LAA
Mb0433c|M.bovis_AF2122/97 VA----LVAAQLGQTLVD-SHAWLVVLTALGS---------------LAA
MMAR_0740|M.marinum_M VA----LVSAQLGQTLLD-SHDWLVVLTALGS---------------LAA
TH_2876|M.thermoresistible__bu RGSAGRYMSMVSGPRVIS-APSIRIMRVRLGIPLGVRGDVRSERATAFDS
Mvan_1651|M.vanbaalenii_PYR-1 IG----LVSTQLAQTLID-SRSPLVVATALGS---------------FAT
MAV_5219|M.avium_104 TA----LVTTQLAQTLLTRRHSPLVVATALGS---------------AGV
MUL_4826|M.ulcerans_Agy99 TA----LVTTQLAQTLLTRSHSPLVLATAFGS---------------AGV
MLBr_02671|M.leprae_Br4923 TA----LVTTQLAQTLLTRRHSPLVVATALGS---------------AGV
MAB_0962|M.abscessus_ATCC_1997 AALITELVAAVWVLAVVARPYQWWRVALVALSG---------------LG
:
Mflv_0956|M.gilvum_PYR-GCK AVIVLQVLVVQLDVLQNLFDTTELTSAQ-------WLFAIAVGSSVLVVD
MSMEG_3926|M.smegmatis_MC2_155 ACTALQLVFTYAPAMNAVFGSTPLGYVD-------WIKAAAVGAPVFGVV
Rv0425c|M.tuberculosis_H37Rv LATLISIP-----VVSQLLGCTPLDPLG-------WAQATAAATAATVAV
Mb0433c|M.bovis_AF2122/97 LATLISIP-----VVSQLLGCTPLDPLG-------WAQATAAATAATVAV
MMAR_0740|M.marinum_M MGTLISIP-----IVSQLLGCTPLDPVG-------WAQALGAAAAATAAM
TH_2876|M.thermoresistible__bu ATEVLSDANHLFCSRTRGFGARVVAHIGGTRQALAWAQPLRHREAAAHER
Mvan_1651|M.vanbaalenii_PYR-1 LAGVISTP-----GVSQVFGCTPVGPVG-------WGQAFSATAVAALLS
MAV_5219|M.avium_104 LVGIVQTP-----VLSQFFGCTPLGPVA-------WTGVLGSTAGATAIS
MUL_4826|M.ulcerans_Agy99 LIGIIQTP-----VVSHFFGCTPLGPVA-------WTGVFSATAGATAVS
MLBr_02671|M.leprae_Br4923 LIGIIQTP-----VISQFFGCTPLGPIA-------WSGVITATAGATAVS
MAB_0962|M.abscessus_ATCC_1997 YVAIFAIP---LARKAFMLDPGNLAVTG---------PALGIGIAAAAVI
. :. : .
Mflv_0956|M.gilvum_PYR-GCK EIGKAVVRT-----------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 ELEKFMVR------------------------------------------
Rv0425c|M.tuberculosis_H37Rv AVLNRVLTGRDKS--------------GQPNPQPPETDALSRDASPGAPP
Mb0433c|M.bovis_AF2122/97 AVLNRVLTGRDKS--------------GQPNPQPPETDALSRDASPGAPP
MMAR_0740|M.marinum_M AVVDRVLDGRAQQ--------------PDPPAPPAPNTSTSPTPEPATAP
TH_2876|M.thermoresistible__bu MVPREGPVGRDTRHSIRWGVRWGVRWGARSGGGGAGADRDHRTRLPGAGP
Mvan_1651|M.vanbaalenii_PYR-1 ATAPELLN------------------------------------------
MAV_5219|M.avium_104 ALAP----------------------------------------------
MUL_4826|M.ulcerans_Agy99 ALAP----------------------------------------------
MLBr_02671|M.leprae_Br4923 VLAP----------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 EAVWWLQG------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------ARRRRRRRVSGADRPREARPASGR------------------
MSMEG_3926|M.smegmatis_MC2_155 ----------RRKARAALAGEEPKGGHTAAHR------------------
Rv0425c|M.tuberculosis_H37Rv GPR--RRRRATARRKAPVKAPSATRQTTKPKGPPAHRSSSTYPRR-----
Mb0433c|M.bovis_AF2122/97 GPR--RRRRATARRKAPVKAPSATRQTTKPKGPPAHRSSSTYPRR-----
MMAR_0740|M.marinum_M AGRSPRARRATTAHKSPATAQSAPQQTTKLADRPGRRSS-TYFRR-----
TH_2876|M.thermoresistible__bu RGARLRRPVAQQVPRRLPGQDRHQAGETLSGDRGGQRGGGRFHRRRAGRG
Mvan_1651|M.vanbaalenii_PYR-1 RATDAVRKRVADVVESVPVVDDDDAGLDEDGVEGADR------RRQQ---
MAV_5219|M.avium_104 ----------NWLAKQVAALEPGQQDA-----------------------
MUL_4826|M.ulcerans_Agy99 ----------KWLAKTVDVALEHQDWASGSA-------------------
MLBr_02671|M.leprae_Br4923 ----------QWLNKAFGIAQLNQE-------------------------
MAB_0962|M.abscessus_ATCC_1997 ----------KWSGQPRHFWATGDD-------------------------
.
Mflv_0956|M.gilvum_PYR-GCK ----------
MSMEG_3926|M.smegmatis_MC2_155 ----------
Rv0425c|M.tuberculosis_H37Rv ----------
Mb0433c|M.bovis_AF2122/97 ----------
MMAR_0740|M.marinum_M ----------
TH_2876|M.thermoresistible__bu HIGRALGGDR
Mvan_1651|M.vanbaalenii_PYR-1 ---MDTGGD-
MAV_5219|M.avium_104 ----------
MUL_4826|M.ulcerans_Agy99 ----------
MLBr_02671|M.leprae_Br4923 ----------
MAB_0962|M.abscessus_ATCC_1997 ----------