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VTDVASGAASTARAAAGMVQDAAAGAPAAVQTAAAITTEALGGHPVKRSSRLNSHHWIEICGLSGPDADA IADEVLAAVHAVAGVRHAEINRSVARVIVTTEPEGPAENLAQVVADAERRVRTGPCGDRHRPLTLPGDDA LLAARTLGALAAVAGFGLSVTGNALRVPRVMELLAVVPTMAANVPQLRRQFEHRLGRDSTDLLLSLMNAA ASALTASPTSAAAEAATRTLLAAEAWDARVAWRRHEPRLAAYPPEGGFPDRGTLEWDYGPSERYAERIGE AGLAAATIIGAVTRNPTIAASAALVTAPKPSRAARDAFGAAMTRGLTNQHDVVVVRPRALRHLDRLDAIV IDPRALYTDKLTVTRIVGVTNSRRTHAWEAVRAALDADSMSPGWHKLSTIPGAGRAGKALVSPVRDPLAN AVVTEARRTKPRVVSIADDGLRSLAQGFDRLYPVDGSIDEALAAAVDELKADGATVALLTTPDLSANQDA DLTIGLERPGWPPPWGADVFVPDLLSVWRILHSLPTARAVTARGVRLSVSATTLGALMLIPGVPGSGPES VSVGVVGALWSGFTAGSKVFRDPPPEPESVHDWHAMPVAEVERLLPRPPDEEPDVSTGLTDLPPLRALSQ AGTWSWHLTRDFVAEMRTNLSDPITPLLATGAVASALLGSPLDAALVGGVLLANAALSAEQQLHAERILQ RLMAVEEPLARRRVGPLDQRRNERVSASRLRPGDIIEVHADEVVPADARLIEATNIEVDESSLTGESLPV PKQTDPTPGAPLAERACMLYAGSTLVAGTAVAVVTTVGSRTEMRRALAMAPDKSREIGLQRQLSRITKRA LPFSVGGGALVGLLSLARGTPLREAVGSSVALTVAAVPEGLPLVATLAQLASARRLTGESVLIRNAQSIE AMARLQVVCFDKTGTLSENRLRVKAVRPIDGFTEEQALDAALSTIFVRAGHRAHHATDDAIRRAVHGDED AADTTEIERDAFLPFQAGRPFAAAIVGTRLTIKGAPEVLASALAQANGPAVAAIDDMAAKGLRVIAVAER QLTPEQAAAAAADAAAFEELCRSDLTPIGLLGLADTPRASAQDVLKELGNRGIGVRLITGDHPVTAMVIA GELGLDVTAEQVMTGAEWEGLSAEERSEAVVSRIVYARMSPEHKIDVVQTLERIGMVTAMVGDGANDAAA IRAASVGFGVASRGSDPARTAADVVLLDGRIEALLDALDEGKQLWRRVQSAVSMLLGGNTGEIAFALITS LLTGRSVLNARQMLLVNMLTDALPAAALAVSRQTDTTGQVDLDEAAMWRAIGVRGAATTVGATSAWAMAS MTGTPQRASTVALIGLVSTQLAQTLIDSRSPLVVATALGSFATLAGVISTPGVSQVFGCTPVGPVGWGQA FSATAVAALLSATAPELLNRATDAVRKRVADVVESVPVVDDDDAGLDEDGVEGADRRRQQMDTGGD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1651 | - | - | 100% (1467) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
| M. vanbaalenii PYR-1 | Mvan_1648 | - | 4e-75 | 27.65% (926) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
| M. vanbaalenii PYR-1 | Mvan_1388 | - | 1e-72 | 31.79% (692) | magnesium-translocating P-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0433c | ctpH | 0.0 | 46.93% (1468) | metal cation transporting P-type ATPase CtpH |
| M. gilvum PYR-GCK | Mflv_0956 | - | 1e-68 | 28.17% (845) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
| M. tuberculosis H37Rv | Rv0425c | ctpH | 0.0 | 47.00% (1468) | metal cation transporting P-type ATPase CtpH |
| M. leprae Br4923 | MLBr_02671 | - | 0.0 | 35.58% (1599) | putative cation transport ATPase |
| M. abscessus ATCC 19977 | MAB_0962 | - | 6e-49 | 27.59% (725) | cation-transporting ATPase E |
| M. marinum M | MMAR_1228 | ctpH_1 | 0.0 | 64.37% (1454) | metal cation transporting p-type ATPase CtpH_1 |
| M. avium 104 | MAV_5219 | - | 0.0 | 36.74% (1614) | ATPase, P-type (transporting), HAD superfamily protein, subfamily |
| M. smegmatis MC2 155 | MSMEG_3926 | - | 2e-72 | 28.76% (831) | cation-transporting ATPase Pma1 |
| M. thermoresistible (build 8) | TH_2876 | - | 0.0 | 65.22% (1360) | PUTATIVE ATPase, P-type (transporting), HAD superfamily, |
| M. ulcerans Agy99 | MUL_4826 | ctpI | 0.0 | 35.67% (1615) | cation-transporter ATPase I CtpI |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 ----------MPVRAVATGFRATATLTGASITAATAVSATLAKTGVGTGM
Rv0425c|M.tuberculosis_H37Rv ----------MPVRAVATGFRATATLTGASITAATAVSATLAKTGVGTGM
Mvan_1651|M.vanbaalenii_PYR-1 --------------------------------MVTD-VASGAASTAR-AA
TH_2876|M.thermoresistible__bu -----MGVLRSTVGGLIGASLRTLQVAAGTALLAGD-TVIGAGRTVAGTV
MMAR_1228|M.marinum_M -------MNNSITRYLPGFGLVTAPLRAGALLAATAGSTALLGGNVAASI
MAV_5219|M.avium_104 -----------------------MVRAGVSTAAGAAGALQTLASPVAELA
MUL_4826|M.ulcerans_Agy99 MKIPGVVNPVANLVAGVTGGAVQMVRAGVQTAADAAGVLQTLASPVVELA
MLBr_02671|M.leprae_Br4923 MKIPHVTDPVSNMVG----GMAQVVRASTHAATGAVNTMQMLASPVAEFA
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 KVAIIPLRAGAKALSG---ELSRETLG----RNCWRGERRAWIEVRGLRS
Rv0425c|M.tuberculosis_H37Rv KVAIIPLRAGAKALSG---ELSRETLG----RNCWRGERRAWIEVRGLRS
Mvan_1651|M.vanbaalenii_PYR-1 AGMVQDAAAGAPAAVQTAAAITTEALGGHPVKRSSRLNSHHWIEICGLSG
TH_2876|M.thermoresistible__bu ADLAADVATGAESTAHTTLGLVVEALGGPPARRTSRNDSRHWIEVCGLSG
MMAR_1228|M.marinum_M GKSLARATPDVPALARAAAGVAVEAMGGPPARRCSTNGRRRWIEVRGLSG
MAV_5219|M.avium_104 GPVIQSMAQTTGRAIGLDGSADGAP-AIVPPVRWHSGRRVHLDLDPLLPF
MUL_4826|M.ulcerans_Agy99 GPVVQSVAQTTNRAIGRNGAADGAPDGVTPPLRWHSGRRVHFDLDPLLPF
MLBr_02671|M.leprae_Br4923 WPVVQSVAKSTGRALGTGHSPNFAN-RVDPPVRWHNGQRVHLDLDPLLPF
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 GGDDELGRVVLNAIQAHPGVGSASLNYPLSRVVVAIDDPD--TSLRELCR
Rv0425c|M.tuberculosis_H37Rv GGDDELGRVVLNAIQAHPGVGSASLNYPLSRVVVAIDDPD--TSLRELCR
Mvan_1651|M.vanbaalenii_PYR-1 PDADAIADEVLAAVHAVAGVRHAEINRSVARVIVTTEPEG---PAENLAQ
TH_2876|M.thermoresistible__bu PDADAIAEEVVSALRAVPGVTDVAINHSMARAVVTVETGV---PAADLTA
MMAR_1228|M.marinum_M DDAAAIAGDVLAAVRQTPGVHTAFLNRTLARLVVTLDAEAEGPSTAQLCR
MAV_5219|M.avium_104 PRWHEYAPAVEEPVRRIPGVAKAHVEGSLGRLVVELADDAD--NAAVLDE
MUL_4826|M.ulcerans_Agy99 PRWHEHAAVVEEPVRRIPGVAKAHVEGALGRLVVELEDGAD--SDTVLDE
MLBr_02671|M.leprae_Br4923 PRWHEYAAVVEEPVRRIPGVAKGHVEGSLGRLVIELDKNAD--SDVVLGK
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 IVDDAEKAERHRHPDQAADQLAQSPGSLPGDGVLLAVRAVTVAATAAGLG
Rv0425c|M.tuberculosis_H37Rv IVDDAEKAERHRHPDQAADQLAQSPGSLPGDGVLLAVRAVTVAATAAGLG
Mvan_1651|M.vanbaalenii_PYR-1 VVADAERRVRTGPCGD-----RHRPLTLPGDDALLAARTLGALAAVAGFG
TH_2876|M.thermoresistible__bu VVAEAERRARTTEAG------RHRPHTLPWDDALLAARAVGAAAAAVGLG
MMAR_1228|M.marinum_M IVAAAEGRHRTRTTG-------QQPTGLPGDDVVLMGRMIAAGAATMGLG
MAV_5219|M.avium_104 VRSTVASVAADISWSKAEAAPPSAPFADPGNPLAILVPLTAAALDLVAMG
MUL_4826|M.ulcerans_Agy99 VCDTAATVAADIFLSGSASSPNSAPFADPGNPLAVLVPLTAAALDLAALG
MLBr_02671|M.leprae_Br4923 VRDVVIALAADLALTGARSAPKVAPFADPGNPLAILMPLTAAVMDLVALS
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 LALGGRALRWPRFPLVIEAAVAAVDHQPLLRRLLEDRIGTAATATVLELA
Rv0425c|M.tuberculosis_H37Rv LALGGRALRWPRFPLVIEAAVAAVDHQPLLRRLLEDRIGTEATATVLELA
Mvan_1651|M.vanbaalenii_PYR-1 LSVTGNALRVPRVMELLAVVPTMAANVPQLRRQFEHRLGRDSTDLLLSLM
TH_2876|M.thermoresistible__bu LSVTGNVLRFRGLPDFLSAIPTLADHNPGIHRQFERRLGREGTDLLFSLL
MMAR_1228|M.marinum_M LSLTGSLLRLPRLPDLVAVPPTLIDHLPRLRRELEKRLGPEGTDVLFGVV
MAV_5219|M.avium_104 AAVTGWVTRLPAAPQTTRAAAALINHQPRMVSILEARLGRVGTDIALAAT
MUL_4826|M.ulcerans_Agy99 AAVTGWVIRLPAAPQTTRAAAALINHQPRMVSLLESRLGRVGTDIALAAT
MLBr_02671|M.leprae_Br4923 AAVTGWVTRLPAVPQTIRAAAALVNHQPRMVSLLESRLGRVGTDIALSIT
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 MAAAHTVTLSPAALSVDLTIQALKAAECRAGARAWRRHEPQLALHADEPA
Rv0425c|M.tuberculosis_H37Rv MAAAHTVTLSPAALSVDLTIQALKAAECRAGARAWRRHEPQLALHADEPA
Mvan_1651|M.vanbaalenii_PYR-1 NAAASALTASPTSAAAEAATRTLLAAEAWDARVAWRRHEPRLAAYPP--E
TH_2876|M.thermoresistible__bu TSASAAMTVSPTSAAAEMATRTMMVVEAVHTRRAWRRHEPRLVRHRP--S
MMAR_1228|M.marinum_M NASTAALTLSPTAAAAEAATRAMLAAEAWNGRSTWFRHEPRLGSYATPDA
MAV_5219|M.avium_104 TAAAHGLTQSFGTPLLDLTQRTLQISEAAAHRRVWRDREPQLASPDRPQA
MUL_4826|M.ulcerans_Agy99 TAAANGLTQAVSTPLLDLVQRGLQISEATAHRRVWRDREPALASPGRPQA
MLBr_02671|M.leprae_Br4923 TAAASGLTQAVGTPLLDLACRGLQLSEAAAHQRVWRDREPQLASPKRPQA
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 DQPQSLWPRPARSTQ-----------------------------------
Rv0425c|M.tuberculosis_H37Rv DQPQSLWPRPARSTQ-----------------------------------
Mvan_1651|M.vanbaalenii_PYR-1 GGFPDRG-TLEWDYG-----------------------------------
TH_2876|M.thermoresistible__bu SRRPHRG-TLEFGAG-----------------------------------
MMAR_1228|M.marinum_M TAATPKR-ISSPPDG-----------------------------------
MAV_5219|M.avium_104 PVVPVISSA--KSEVPRHSWAAAAAGEASHVVVGGTIDAAMDKAKGSMAG
MUL_4826|M.ulcerans_Agy99 PVVPVISSAGVQAQEPRHSWAAAAAGEASHVMVGGSIDAAIDTAKGSMAG
MLBr_02671|M.leprae_Br4923 PVVPVISSAGEKSHAAGHNWTAAASNEASHLVVGGSIDAAIDTAKGSMKG
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 PVQRSVARFALIQALSAVLVGAGTRDADMAATATLVATPKASRTTPEAFA
Rv0425c|M.tuberculosis_H37Rv PVQRSVARFALIQALSAVLVGAGTRDADMAATATLVATPKASRTTPEAFA
Mvan_1651|M.vanbaalenii_PYR-1 PSERYAERIGEAGLAAATIIGAVTRNPTIAASAALVTAPKPSRAARDAFG
TH_2876|M.thermoresistible__bu AGERYADRAVRMGVTAAAVVGAVSRNPTIGGAAALVTAPKPSRAAREAFG
MMAR_1228|M.marinum_M PAERYANRIGLTGLGAAAVVGLLSRNPDSAGAAALAAVPKPLRTVREAFG
MAV_5219|M.avium_104 PVESYVDSAANGSLIAAVSALVAGGGTEDAAAAIEAGVPRAAHMGRQAFA
MUL_4826|M.ulcerans_Agy99 PVESYVNSAANGALIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQAFA
MLBr_02671|M.leprae_Br4923 PVESYVDSAANGSLIAAASALLAGGGTEDAAGAILAGVPRAAHMGQQAFA
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 AALGQGLADQHAVLPLRPESLRRLDRVDAIVIDPRVLCTDDLRVARIRGC
Rv0425c|M.tuberculosis_H37Rv AALGQGLADQHAVLPLRPESLRRLDRVDAIVIDPRVLCTDDLRVARIRGC
Mvan_1651|M.vanbaalenii_PYR-1 AAMTRGLTNQHDVVVVRPRALRHLDRLDAIVIDPRALYTDKLTVTRIVGV
TH_2876|M.thermoresistible__bu CAMTRGLITHHDALVVRPRALRALDRVDAVVIDPRVLYTDQLAVTRIVGV
MMAR_1228|M.marinum_M CALSNGLTSQHDALVLRPRALRALDRVDAIMIDPRALYTDELTVSRVLGV
MAV_5219|M.avium_104 AVLGRGLANS-GQLVLDPGALRRLDRVKVVVIDGAALRGDHRAVLRVRGE
MUL_4826|M.ulcerans_Agy99 AVLGRGLASE-GQLVLDPGALRRLDRVQVVVIDGAALRGDHRSVLRAQGD
MLBr_02671|M.leprae_Br4923 ATLGRGLANA-GQLVLDPGALRRLDQVKVVVIDGAALRGDHRAVLLARGN
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 GADELSTAWNRAQLVLTESGLRPG--------------WHRVPGVSASGS
Rv0425c|M.tuberculosis_H37Rv GADELSTAWNRAQLVLTESGLRPG--------------WHRVPGVSASGS
Mvan_1651|M.vanbaalenii_PYR-1 TNSRRTHAWEAVRAALDADSMSPG--------------WHKLSTIPGAG-
TH_2876|M.thermoresistible__bu TNSDRDRAWRAVQRALDRGGLTPG--------------WHPLSSIAGAP-
MMAR_1228|M.marinum_M QNSARGKAWEAVAAALDDQRLAPG--------------WHHLADIPGAG-
MAV_5219|M.avium_104 APGWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPSQGPSAMPA
MUL_4826|M.ulcerans_Agy99 EPGWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPLRGPSATPA
MLBr_02671|M.leprae_Br4923 TPGWDDDRVYEVTDALLHGERAPEPDPDESPATGARLRWVPLQGPSATPV
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 ------------DSAVEALFRPMHDRLASAVVAEAHRTGADLVSVDVDAL
Rv0425c|M.tuberculosis_H37Rv ------------DSAVEALFRPMHDRLASAVVAEAHRTGADLVSVDVDAL
Mvan_1651|M.vanbaalenii_PYR-1 -------------RAGKALVSPVRDPLANAVVTEARRTKPRVVSIADDGL
TH_2876|M.thermoresistible__bu -------------ASGRILISPVRDQFAAAVVTEAHRCGRRVLSLDDDGL
MMAR_1228|M.marinum_M -------------RTGRALISPVRDPYAAAVITEARRARPRVFSLEDDGL
MAV_5219|M.avium_104 QGLESADLIVDGDRVGRVDVGWEVDPYAIPLFQTAHRTGARVVLRHVAGT
MUL_4826|M.ulcerans_Agy99 QGLEHADLVVDGQTVGNVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGT
MLBr_02671|M.leprae_Br4923 QGREHADLVVNGECVGGVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGT
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 GELRPVFDDIRPLDDGASGSLDEALARAVAELRQAGRTVAVLSSVGKQAL
Rv0425c|M.tuberculosis_H37Rv GELRPVFDDIRPLDDGASGSLDEALARAVAELRQAGRTVAVLSSVGKQAL
Mvan_1651|M.vanbaalenii_PYR-1 RSLAQGFDRLYPVDG----SIDEALAAAVDELKADGATVALLTTPDLSAN
TH_2876|M.thermoresistible__bu RSLARGFDKLYPLGD----SVDESLAAAVAEAKADGATVALFTSPAMTAP
MMAR_1228|M.marinum_M RSLAQGFDHLYPSAE----SIDDAMAAALAELKAGGATVALLTTSALQAE
MAV_5219|M.avium_104 EDLTASVGATHPPGTPLLNVVRELRADRGPVLLITALHRDFASTDTLAAL
MUL_4826|M.ulcerans_Agy99 EDLSASVGSTHPPGTPLLNLVRELRTDPGPVLLITALHRDFASTDTLAAL
MLBr_02671|M.leprae_Br4923 EDLSASVGATHPPGTPLLKLVRELRTDRGPVLLITAVHRDFASTDTLAAL
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 SAADVALGVLPPPGAGAPPWYADVLLP-DLGAAWRVLHAIPAARAARQRG
Rv0425c|M.tuberculosis_H37Rv SAADVALGVLPPPGAGAPPWYADVLLP-DLGAAWRVLHAIPAARAARQRG
Mvan_1651|M.vanbaalenii_PYR-1 QDADLTIGLERP--GWPPPWGADVFVP-DLLSVWRILHSLPTARAVTARG
TH_2876|M.thermoresistible__bu HAADITIGLSPD--GHPPPWGADVFVP-DLVSMWRILRALPAARSATTKG
MMAR_1228|M.marinum_M HRSDVTIGVLRA--RHPPPWGADVLVS-DLTGAWRVLHALPAARTATDSA
MAV_5219|M.avium_104 AIADVGVALDDP--RAATAWTADIITGTDLADAVRILSAIPVARSASESA
MUL_4826|M.ulcerans_Agy99 AIADIGVALDDP--RAATPWTADIITGTDLAAAVRILSAIPVARASSVSS
MLBr_02671|M.leprae_Br4923 AIADVGVALDDP--HAATPWTADIITGTDLAAAVRILSALPVARSASESS
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 --------------------------------------------------
Mb0433c|M.bovis_AF2122/97 NEISGGASALGALLMLPGVR----------GLGPGPVTTGAAAGLLSGYL
Rv0425c|M.tuberculosis_H37Rv NEISGGASALGALLMLPGVR----------GLGPGPVTTGAAAGLLSGYL
Mvan_1651|M.vanbaalenii_PYR-1 VRLSVSATTLGALMLIPGVP----------GSGPESVSVGVVGALWSGFT
TH_2876|M.thermoresistible__bu VRLSASSTAIGALMLIPGVT----------GNGPDSVNVGVAAGLWSGFR
MMAR_1228|M.marinum_M IRLSASASAIGALMLIPSVP----------GRGSASVNVGMAVSLYLGFR
MAV_5219|M.avium_104 VHLAQGGTTLAGLLLVTGEQ-EKGASPVSFRRWLNPVNAAAATALVAGTF
MUL_4826|M.ulcerans_Agy99 VHLAQGGTTLAGLLLVTGEQ-ARTTNPASFRRWLNPVNTAAATALLSGSW
MLBr_02671|M.leprae_Br4923 VHLAQGGTTLAGLLLITASAGSKSASPITLRRWFSPVNAAAATALVTGVV
MAB_0962|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK ---------------MSDWHARSVREVTDALDTDVTAGLTSEAAEER---
MSMEG_3926|M.smegmatis_MC2_155 ---MRRPADAGGNSNENNWHTMQPDEVLDALGASR-SGLTDSEVERR---
Mb0433c|M.bovis_AF2122/97 LARKVVDAQAPRPAPAHEWHAMSVEQVRKALPSPDEQAPAKAPPSPYPAR
Rv0425c|M.tuberculosis_H37Rv LARKVVDAQAPRPAPAHEWHAMSVEQVRKALPSPDEQAPAKAPPSPYPAR
Mvan_1651|M.vanbaalenii_PYR-1 AGSKVFRDPPPEPESVHDWHAMPVAEVERLLPRPPD--EEPDVSTGL---
TH_2876|M.thermoresistible__bu TATKVFDDSPPEPEPSHDWHALPADEVRRLLPRPGDGDRQPPAGRDP---
MMAR_1228|M.marinum_M SGTKVFHDTVPEPDAGHDWHSLPIAEVQRLLPRPAE-EDRRDAENRW---
MAV_5219|M.avium_104 SATRVLRLPDPTPQPLTAWHALDPEIVYSRLAGGARPLAVET-EPSWRR-
MUL_4826|M.ulcerans_Agy99 SAATVLRLPDPTPQPLTAWHALDPEIVYARLAGGARPMAVDPGTPTWRR-
MLBr_02671|M.leprae_Br4923 SASKVLRLPDPTPQPLTAWHALDPEIVYSRLAGVTQPLAVEPGTPDWRR-
MAB_0962|M.abscessus_ATCC_1997 ---------------MATIEGLTISGLTAAEVAERVAQGKTNDVPSR---
. :
Mflv_0956|M.gilvum_PYR-GCK ---------RHRHGPNQLTEAAAVPVWRKVLRLLADKMTLVLLVAAAVSA
MSMEG_3926|M.smegmatis_MC2_155 ---------RAVHGWNRLAAVRKQSALVPFIRQFHNVLIYVMSCAAIVTA
Mb0433c|M.bovis_AF2122/97 ALAGGLHTAKRGAQITQAPLNALWQLTKAVRAELSDPLTPMLALGAMASA
Rv0425c|M.tuberculosis_H37Rv ALAGGLHTAKRGAQITQAPLNALWQLTKAMRAELSDPLTPMLALGAMASA
Mvan_1651|M.vanbaalenii_PYR-1 ---TDLPPLRALSQAGTWSWHLTRDFVAEMRTNLSDPITPLLATGAVASA
TH_2876|M.thermoresistible__bu ---ALMRPVRAAAAAMTWFWQLTRDFTAEMRSNLADPITPLLATGAVASA
MMAR_1228|M.marinum_M ---EKLPPIRMVHRGTAASLRLVRDFAAEMRDDLSDPITPMLATGAAASA
MAV_5219|M.avium_104 --RLDDLSYSPALAPLRAPLQNVLRLASATRTELADPLTPILAVGAAASA
MUL_4826|M.ulcerans_Agy99 --LLDDLSYEPLVSPLRGPAHTLAQLAAATRHELADPLTPILAVGAAASA
MLBr_02671|M.leprae_Br4923 --RLDDLSYTRALSPLRKPVTKLARLASATRQEFADPLTPILAVGAAASA
MAB_0962|M.abscessus_ATCC_1997 -------------AARSVSDIVRANVFTRINAILGVLLIIVLSTGSIING
: : :: .: ..
Mflv_0956|M.gilvum_PYR-GCK VVSREWETPVVIMLVVTLNTVLNYVQEARAENSLQALRDMSISYSR----
MSMEG_3926|M.smegmatis_MC2_155 VLQ-HWVDAAVLFAAVLINVVIAYVQEGRAQAALDAIRAMMSPHAT----
Mb0433c|M.bovis_AF2122/97 VLG-SPVDAVMVGSVLTGNSILAASQRLRAESRLNRLLAQQIPPARKVLA
Rv0425c|M.tuberculosis_H37Rv VLG-SPVDAVMVGSVLTGNSILAASQRLRAESRLNRLLAQQIPPARKVLA
Mvan_1651|M.vanbaalenii_PYR-1 LLG-SPLDAALVGGVLLANAALSAEQQLHAERILQRLMAVEEPLARRRVG
TH_2876|M.thermoresistible__bu LLG-SPLDAALVGGVLLLNAALSAQQQLHAERILRRLMAVQEPSARRRVR
MMAR_1228|M.marinum_M LLG-SPLDAFLVSSVLLLNAALSAEQQLHAERILNRLLAVQDPPARRRLG
MAV_5219|M.avium_104 IVG-SNIDALLVAGVMTVNAITGGAQRLRAESAAAELFAEQDQMVRRVVV
MUL_4826|M.ulcerans_Agy99 IVG-SNVDALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQMVRRVVV
MLBr_02671|M.leprae_Br4923 IVG-SNIDALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVV
MAB_0962|M.abscessus_ATCC_1997 AFG----------LLIIANSAVGIIQELRAKQILDKLAIVGQTRPL----
. : * *. :*: :
Mflv_0956|M.gilvum_PYR-GCK ---------------VRRDGGEHRLPRTELVPGDVVLLEAGDAVPADGRI
MSMEG_3926|M.smegmatis_MC2_155 ---------------VTRNGRTLDVEAVELVPGDVVQLAAGDRIPADLRL
Mb0433c|M.bovis_AF2122/97 G--------------ADDQPRYIEVRAEELRPGDIIEVRTHEVVPADARV
Rv0425c|M.tuberculosis_H37Rv G--------------ADDQPRYIEVRAEELRPGDIIEVRTHEVVPADARV
Mvan_1651|M.vanbaalenii_PYR-1 ---------------PLDQRRNERVSASRLRPGDIIEVHADEVVPADARL
TH_2876|M.thermoresistible__bu MATATGTGATGTEATPVEAGPIEEVPANRLRPGDVIEVRVGDVVPADARI
MMAR_1228|M.marinum_M ---------------PLDEQRREKVPAKRLRPGDIIEVHADEVVPADARL
MAV_5219|M.avium_104 PAVATTR---RRLEAARHATRTATVSAKSLRPGDVIDLAAPEVVPADARL
MUL_4826|M.ulcerans_Agy99 PAVATTR---RRLEAARHATRTATVSAKSLRVGDVIDLAAPEVVPADARL
MLBr_02671|M.leprae_Br4923 PAVATTR---RRLEAAQHATRTVTVSAKSLRAGDVIDLAAPEVVPADARV
MAB_0962|M.abscessus_ATCC_1997 ---------------VRRDGAATALAPNEVVLDDIIELGPGDQIVVDGEV
: : .*:: : : : .* .:
Mflv_0956|M.gilvum_PYR-GCK VSAARLQVAESALTGESAPVDKAVDGLDDTDLPLGDRTNMLYMNTEVTRG
MSMEG_3926|M.smegmatis_MC2_155 IGVDGLQVDEAPLTGESAPVWKTIG-VDDEDTSLPDRRSMAYSGTLAIHG
Mb0433c|M.bovis_AF2122/97 IEEVDVEVDESALTGESLSVTKQVE--PTPGVDLIERRCMLYAGTTVVSG
Rv0425c|M.tuberculosis_H37Rv IEEVDVEVDESALTGESLSVTKQVE--PTPGVDLIERRCMLYAGTTVVSG
Mvan_1651|M.vanbaalenii_PYR-1 IEATNIEVDESSLTGESLPVPKQTD--PTPGAPLAERACMLYAGSTLVAG
TH_2876|M.thermoresistible__bu MAASNVEVDESSLTGESLPVPKTAA--ATPGAPLAERSGMLYAGTTMVAG
MMAR_1228|M.marinum_M LHASSVEVDESTLTGESLPVSKQTE--PTPGAPLAERACMLYAGTTMVAG
MAV_5219|M.avium_104 LEAEDLEVDESLLTGESLPVDKQVE--PVA-VNDPDRASMLFEGSTIVAG
MUL_4826|M.ulcerans_Agy99 LVAEDLEVDESLLTGESLPVDKQVD--PVA-VNDADRASMLFEGSTIVAG
MLBr_02671|M.leprae_Br4923 LVAEDLEVDESLLTGESLPVDKRVD--PVA-INDADRASMLFEGSAIVAG
MAB_0962|M.abscessus_ATCC_1997 IEESALEIDESLLTGEADAIEKTIG-------------SQVLSGSFVVAG
: ::: *: ****: .: * .: *
Mflv_0956|M.gilvum_PYR-GCK RATMVVTATGMDTEVGAIATMLGTAGVSRTPLQQRIDNLAQMLTVVALLV
MSMEG_3926|M.smegmatis_MC2_155 QATGVVVGTGAQTELGRINHLLTGVAPTATPLLRQISRFGRVLAVVILLL
Mb0433c|M.bovis_AF2122/97 TAVAVVTAVGPDTQERRAAELVSGDLSSVG-LQHQLSRLTNQAWPVSMTG
Rv0425c|M.tuberculosis_H37Rv TAVAVVTAVGPDTQERRAAELVSGDLSSVG-LQHQLSRLTNQAWPVSMTG
Mvan_1651|M.vanbaalenii_PYR-1 TAVAVVTTVGSRTEMRRALAMAPDKSREIG-LQRQLSRITKRALPFSVGG
TH_2876|M.thermoresistible__bu TAVAVVTAVGPRTEVRRALAMAAERPGEIG-LQRQLAHITKRALPFSVSS
MMAR_1228|M.marinum_M TAVAVVTAVGSRSEMRRALAMAPRKSREIG-LQRQLSRITRRALPFSVAS
MAV_5219|M.avium_104 HARAIVVATGVGTAAHRAISAVADVETAAG-VQARLRELTSKVLPLTLAG
MUL_4826|M.ulcerans_Agy99 RARAIVVATGAGTAAHRAISAVADVETSAG-VQARLRELTSKVLPLTLAG
MLBr_02671|M.leprae_Br4923 HARAIVVATGVGTAAHRAISAVADVEVSAG-VQARLRELTSKVLPLTLAG
MAB_0962|M.abscessus_ATCC_1997 SGAYRATKVGREAYAAKLAEEASKFTLVHSELRNGINKILQFITYLLLPA
. .. .* : : : .: . :
Mflv_0956|M.gilvum_PYR-GCK VIVVTVLG-LLRGDTWTELLLTAVSLAVATIPEGLTAVVAFTLAMGASRL
MSMEG_3926|M.smegmatis_MC2_155 SAATYALGVIWRGETLTEMFMMTVALAASAIPEGLPAIMTVTLAIGVQRM
Mb0433c|M.bovis_AF2122/97 GALVTGLG-LLRRRGLRQAVASGIAVTVAAVPEGMPLVATLAQQASARRL
Rv0425c|M.tuberculosis_H37Rv GALVTGLG-LLRRRGLRQAVASGIAVTVAAVPEGMPLVATLAQQASARRL
Mvan_1651|M.vanbaalenii_PYR-1 GALVGLLS-LARGTPLREAVGSSVALTVAAVPEGLPLVATLAQLASARRL
TH_2876|M.thermoresistible__bu GALVGLLS-VLRGTPIRAAVGSAVSLIVAAVPEGLPLVATLAQLASARRL
MMAR_1228|M.marinum_M GGLVGLLS-MSRGTPLREAVASAVTLVVAAVPEGLTLVVTLAQLAAARRL
MAV_5219|M.avium_104 GAAVSTLA-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLSAAQRL
MUL_4826|M.ulcerans_Agy99 GASVSVLA-LMRRATLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRL
MLBr_02671|M.leprae_Br4923 GAAVTGLA-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRL
MAB_0962|M.abscessus_ATCC_1997 GALIIYTQLFTTDDSWQESVLRMVGALVPMVPEGLVLMTSIAFAVGVIRL
. . : .. :***: : :.: .. *:
Mflv_0956|M.gilvum_PYR-GCK ARRGAIIKQLSAVETLGSTADIATDKTGTLTLNEMTVRRLLLPGREFRVS
MSMEG_3926|M.smegmatis_MC2_155 SRRRAIVCRLPAVEALGSVTVICTDKTGTLTSNEMTVQRVVCGGHDIDVG
Mb0433c|M.bovis_AF2122/97 SHFGALVRIPRSVEALGRVDMVCFDKTGTLSENRLRVAQVRP--------
Rv0425c|M.tuberculosis_H37Rv SHFGALVRIPRSVEALGRVDMVCFDKTGTLSENRLRVAQVRP--------
Mvan_1651|M.vanbaalenii_PYR-1 TGESVLIRNAQSIEAMARLQVVCFDKTGTLSENRLRVKAVRP--------
TH_2876|M.thermoresistible__bu SGESILIRNPNSIEALARLQVVCFDKTGTLSENRLQVKAVHP--------
MMAR_1228|M.marinum_M TGESVLIRNAHSIEALARLNVVCFDKTGTLSENRLKVKTVRP--------
MAV_5219|M.avium_104 TARGALVRAPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPDDV-----
MUL_4826|M.ulcerans_Agy99 TAHGALVRAPRTIEALGRVDTVCFDKTGTLTENRLRVVCAIPSST-----
MLBr_02671|M.leprae_Br4923 TAKGALVRSPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPNTR-----
MAB_0962|M.abscessus_ATCC_1997 GRRQCLVQELPAIEGLARVDTVCADKTGTLTENGMRLADVHFPDR-----
:: ::* :. :. ******: * : :
Mflv_0956|M.gilvum_PYR-GCK GEGYSTDGKILVS----DGRPLPDLTAPLLAMALCSDASVREG----SLV
MSMEG_3926|M.smegmatis_MC2_155 GVGYAPVGDFSIDGRVIDPSRYPALMEALLAASLCNDASLDVEDEVWVIT
Mb0433c|M.bovis_AF2122/97 -------------------------VAGHSREEVLRCAAHAAPASNGP-Q
Rv0425c|M.tuberculosis_H37Rv -------------------------VAGHSREEVLRCAAHAAPASNGP-Q
Mvan_1651|M.vanbaalenii_PYR-1 -------------------------IDGFTEEQALDAALSTIFVRAGHRA
TH_2876|M.thermoresistible__bu -------------------------MRGRTETEVLEAALSTTFAEPGHRA
MMAR_1228|M.marinum_M -------------------------APGFTPGQVLDAALSTTYSRHTHRV
MAV_5219|M.avium_104 ----------------NPHDPFPELTAPQSAELVRAAARASARPQEGQGH
MUL_4826|M.ulcerans_Agy99 ----------------SPLDPFIDSADPRSTEVLRAAARATTQPHDGQGH
MLBr_02671|M.leprae_Br4923 ----------------MPHDPLPDITDPHSAAVLRDAARASTQPHDGQGH
MAB_0962|M.abscessus_ATCC_1997 -----------------------------------DGDEDALAVLAQLAA
Mflv_0956|M.gilvum_PYR-GCK GDPTEGALVVLAEKGGVDVTGARAA--IPRLAEVPFDSEYKYMATFCARS
MSMEG_3926|M.smegmatis_MC2_155 GDPTEAALLVVAKKAGLDHDRETVS--HPRVATVPFASENRIMGTLHS--
Mb0433c|M.bovis_AF2122/97 VHATDVAIVQAAAAAAASGTDGAEPGAAEPAAHLPFRSGRSFSASVSGTE
Rv0425c|M.tuberculosis_H37Rv VHATDVAIVQAAAAAAASGTDGAEPGAAEPAAHLPFRSGRSFSASVSGTE
Mvan_1651|M.vanbaalenii_PYR-1 HHATDDAIRRAVHGDEDAADTTEIE----RDAFLPFQAGRPFAAAIVGTR
TH_2876|M.thermoresistible__bu HHATDEAIIRAVNG---AAIAAPAQ----RDGFLPFQAGRPYAAAVRGTR
MMAR_1228|M.marinum_M EHATDDAIFQAADDPAVRGDGSQPQPRLSRDAFLPFQSGRPFAAALAGTR
MAV_5219|M.avium_104 AHATDEAILTAASSLNGQRDS-----DWSMIAEVPFESSRGFAAAIGTVG
MUL_4826|M.ulcerans_Agy99 AHATDEAIIVAANSLEGLNDS-----AWTVIAEVPFESSRGYAASIGTTG
MLBr_02671|M.leprae_Br4923 THATDEAILTAASSLNSHTDS-----TWSLIAEVPFESSRGYAAAIGITG
MAB_0962|M.abscessus_ATCC_1997 DDPRPNASIAAIAEAYDTPPG------WETTAIAPFSSAKKWSGASYGEH
.. * . ** : .:
Mflv_0956|M.gilvum_PYR-GCK DLDGSGGH--RCFVKGAPGVLLEHAGSVLGEDGPRPIDPGYRQRIRERVE
MSMEG_3926|M.smegmatis_MC2_155 DVDRTP----LIVVKGAPERVLDICDSQRSPHGEEPLDRLYWQRMAA---
Mb0433c|M.bovis_AF2122/97 -----------LTVKGAPEVVLAACEGIG-----SSMDDAVAE-------
Rv0425c|M.tuberculosis_H37Rv -----------LTVKGAPEVVLAACEGIG-----SSMDDAVAE-------
Mvan_1651|M.vanbaalenii_PYR-1 -----------LTIKGAPEVLASALAQA-----NGPAVAAIDD-------
TH_2876|M.thermoresistible__bu -----------LTIKGAPEVLASALARG-----DSALTRRVEA-------
MMAR_1228|M.marinum_M -----------LTIKGSPEVLSAALRRAPEAA-ADPFTKQIDE-------
MAV_5219|M.avium_104 NANGNPSDTPVLILKGAPEVILPRCRFADPEADQQRAEAVVRG-------
MUL_4826|M.ulcerans_Agy99 TSNGHPT----LMLKGAPETILPRCRFADPDADLEHAEALVHS-------
MLBr_02671|M.leprae_Br4923 --NGKAP---MLMLKGAPEKILPRCRFADPEADVAHAESLVRH-------
MAB_0962|M.abscessus_ATCC_1997 G----------NWVIGAPDVLLDPADAIATAAEE----------------
: *:* :
Mflv_0956|M.gilvum_PYR-GCK QLASEGLRTLMIAGRDIDHDLPADPDGLQTLVD-----DLTVYAVVGIVD
MSMEG_3926|M.smegmatis_MC2_155 TTAAQGLRVLAIARR-CGAPRNAGTLDIADLDS-----GFTMLGLVGIID
Mb0433c|M.bovis_AF2122/97 -LAANGLRVIAVAHRQLTAQQAQSVVDDPDEIARLCRDELSLVGFLGLSD
Rv0425c|M.tuberculosis_H37Rv -LAANGLRVIAVAHRQLTAQQAQSVVDDPDEIARLCRDELSLVGFLGLSD
Mvan_1651|M.vanbaalenii_PYR-1 -MAAKGLRVIAVAERQLTPEQAAAAAADAAAFEELCRSDLTPIGLLGLAD
TH_2876|M.thermoresistible__bu -MAAQGLRVLAVAGRELSPEQAAAAVADPAVFTELCGSGLSLFGLIGLAD
MMAR_1228|M.marinum_M -MATGGLRVLAVAERQLRPEQATAAAADPDLLESLCQSELTPVGLLGLAD
MAV_5219|M.avium_104 -LAEQGLRVLAVAQRGWKHDTDDDD-TDADAVDAAAH-NLELLGYVGLAD
MUL_4826|M.ulcerans_Agy99 -LAERGLRVLAVAKRPWEHDTADDDDTDADAVDAAAH-DLELLGYVGLAD
MLBr_02671|M.leprae_Br4923 -LAEQGLRVLAVAQCSWGHDTTDDNDTDADAVDAAAH-DLELVGYIGLAD
MAB_0962|M.abscessus_ATCC_1997 -IGARGLRVLLLASAELSVDDAHAP------------GAVTPRALVVLEQ
. ***.: :* . . : : :
Mflv_0956|M.gilvum_PYR-GCK PPRPEAGEAIATAHAAGITVHMITGDHLSTAAAVAHDLGIPG--AAASG-
MSMEG_3926|M.smegmatis_MC2_155 ALRPEVAAAVRECHRAGIRVKMITGDHAATAREIGAQLGIGIGKPAVIG-
Mb0433c|M.bovis_AF2122/97 TPRAQAAALLADLHEHDLDIRLITGDHPITAAAIAEELGMQVSPEQVISG
Rv0425c|M.tuberculosis_H37Rv TPRAQAAALLADLHEHDLDIRLITGDHPITAAAIAEELGMQVSPEQVISG
Mvan_1651|M.vanbaalenii_PYR-1 TPRASAQDVLKELGNRGIGVRLITGDHPVTAMVIAGELGLDVTAEQVMTG
TH_2876|M.thermoresistible__bu TPRPSARGVLADLTERGIGVRLITGDHPVTAAVTARELGLDVDGEQVITG
MMAR_1228|M.marinum_M TPRPTAQSVLNGLADRDIGVRLITGDHPATATATAQELGLDVTDSEVITG
MAV_5219|M.avium_104 TARASARPLIEALLDAERDVVLITGDHPITARAIARQLGLPADAR-VVTG
MUL_4826|M.ulcerans_Agy99 TARPSARPLIEALVDAQRNVVLITGDHPITARAIARQLGLPEDVR-VVTG
MLBr_02671|M.leprae_Br4923 TARPSSRPLIEALVTAGRNVVLITGDHPITARAIAQQLGLRSDAR-VVNG
MAB_0962|M.abscessus_ATCC_1997 KIRPDARETLDYFASQHVSIKVISGDNAVSVSAVAQTLGLTG----AAVD
*. : : :*:**: :. . **: .
Mflv_0956|M.gilvum_PYR-GCK ADLDRLDDDTLREQSPSFGVLARVAPEHKIRLVKALQSRGHVVAMTGDGV
MSMEG_3926|M.smegmatis_MC2_155 SEIASLNDTDLQTVVQERDIFARASPEHKLRLVRALQAGGEVVAMTGDGV
Mb0433c|M.bovis_AF2122/97 AEWDALSRKDQERAVAERVIFARMTPENKVQIVQTLEHSGRVCAMVGDGS
Rv0425c|M.tuberculosis_H37Rv AEWDALSRKDQERAVAERVIFARMTPENKVQIVQTLEHSGRVCAMVGDGS
Mvan_1651|M.vanbaalenii_PYR-1 AEWEGLSAEERSEAVVSRIVYARMSPEHKIDVVQTLERIGMVTAMVGDGA
TH_2876|M.thermoresistible__bu AEWETLSAEERAAAVRSRSVFARMSPEHKIDVVQTLERNGVVTAMVGDGA
MMAR_1228|M.marinum_M AEWEALSADQRATVVASRLVFARMSPEHKVEVVQALERAGLVTAMVGDGV
MAV_5219|M.avium_104 AELAGLDEDACAKLVADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDGA
MUL_4826|M.ulcerans_Agy99 AELIGLDEDACAKLAADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDGA
MLBr_02671|M.leprae_Br4923 TELIGLDEDACAELAADVQVFARVSPEQKVQIVAALQRCGQVTAMVGDGA
MAB_0962|M.abscessus_ATCC_1997 ARTLPTDTDKLAATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDGV
: . . .* *::* :* :*: * . **.***
Mflv_0956|M.gilvum_PYR-GCK NDAPALKQADIGIAMGITGTDVSKGAANMILTDDNFGTIVAAVREGRGIY
MSMEG_3926|M.smegmatis_MC2_155 NDSPALKKADVGIAMGCRGTEAAKEAADMVLADDNFATIAAAVSEGRTVY
Mb0433c|M.bovis_AF2122/97 NDAAAIRAATVGIGVVAHGSDPARVAADLVLVDGRIESLLPAILEGRQLW
Rv0425c|M.tuberculosis_H37Rv NDAAAIRAATVGIGVVAHGSDPARVAADLVLVDGRIESLLPAILEGRQLW
Mvan_1651|M.vanbaalenii_PYR-1 NDAAAIRAASVGFGVASRGSDPARTAADVVLLDGRIEALLDALDEGKQLW
TH_2876|M.thermoresistible__bu NDAAAIRAASVGVGVATRSSDPARTAADIVLLDGRIEALIDALDEGHHLW
MMAR_1228|M.marinum_M NDAAAIRAASVGIGMAARGSDAARTAADVVLLDGRIDALLEALDEGQQLW
MAV_5219|M.avium_104 NDAAAIRMADVGIGVSGRGSSAARGAADIVLTDQDLSVLLDALVEGRSMW
MUL_4826|M.ulcerans_Agy99 NDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMW
MLBr_02671|M.leprae_Br4923 NDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMW
MAB_0962|M.abscessus_ATCC_1997 NDVLALKDADIGVAMG-AGSSASRAVAQIVLLDNKFATLPYVVAEGRRVI
** *:: * :*..: .:. :: .*:::* * : : .: **: :
Mflv_0956|M.gilvum_PYR-GCK ANIIKFVKFQLTTAWGFVLIFLVCGSLGLAG-GAPFTALQILWVNIIMDG
MSMEG_3926|M.smegmatis_MC2_155 DNIRKFVLFMLPTNGGEALVVIAAILFQFT---LPLTPAQVLWINLVTSS
Mb0433c|M.bovis_AF2122/97 QRVQAAVSVLLGGNAGEVAFAIIGSAITG---TSPLNTRQLLLVNMLTDA
Rv0425c|M.tuberculosis_H37Rv QRVQAAVSVLLGGNAGEVAFAIIGSAITG---TSPLNTRQLLLVNMLTDA
Mvan_1651|M.vanbaalenii_PYR-1 RRVQSAVSMLLGGNTGEIAFALITSLLTG---RSVLNARQMLLVNMLTDA
TH_2876|M.thermoresistible__bu RRVQSAVSMLLGGNSGEIAFALLTSLLTG---RSVLNARXXXTTAADAEP
MMAR_1228|M.marinum_M RRVHSAVSVLLGGNLGEVSFALITTLLTG---RSVFNARQMLLVNMLTDA
MAV_5219|M.avium_104 AGVRDAVTILVGGNVGEVLFTIIGTAFGAG--RAPVGTRQLLLVNLLTDM
MUL_4826|M.ulcerans_Agy99 AGVRDAVTILVGGNVGEVLFTIIGTAFGAG--RAPVGTRQLLLVNLLTDM
MLBr_02671|M.leprae_Br4923 AGVRDAVTILVGGNVGEVVFTIIGTVFGAG--RAPVGTRQLLLVNLLTDM
MAB_0962|M.abscessus_ATCC_1997 GNIERVSNLFLTKTVYSVLLALTVGLAGLGSKIFHYGAVPFPFQPIHVTI
: . : . : .
Mflv_0956|M.gilvum_PYR-GCK PPALALGVDPTEPDVMHQKPR---------------------PPTERLLN
MSMEG_3926|M.smegmatis_MC2_155 TLGLALAFEPPEAGVMRRKPR---------------------APSESLLS
Mb0433c|M.bovis_AF2122/97 LPAAALAVSKPSDPVTPATRG----------------------PDQRELW
Rv0425c|M.tuberculosis_H37Rv LPAAALAVSKPSDPVTPATRG----------------------PDQRELW
Mvan_1651|M.vanbaalenii_PYR-1 LPAAALAVSRQTDTTGQVDL------------------------DEAAMW
TH_2876|M.thermoresistible__bu IPCKARAIPSMVMSGATAHS------------------------TDASMC
MMAR_1228|M.marinum_M LPAAALAVSPQTSN-VEVER------------------------DEAAMW
MAV_5219|M.avium_104 FPALAVAVTSQYVEPDEAEYPSAADAEAARREHRRAVLTGPTPSLDAPLM
MUL_4826|M.ulcerans_Agy99 FPALAVAITSQYDDPEDDSDLSDEEIEEARRRRQRAVLTAPTPSLDAPLM
MLBr_02671|M.leprae_Br4923 FPALSIAVTSQYEEPGEDEYQTDEEADEARRTHQHEVLTGPTPSLDAPLM
MAB_0962|M.abscessus_ATCC_1997 AAWFTIGIPAFILSLAPNNER-----------------------AQTGFV
: .. : :
Mflv_0956|M.gilvum_PYR-GCK RARLQRILVLG-MVMTLGTVTVLMLADDLFPESAGDPLFATTLAFTTFVF
MSMEG_3926|M.smegmatis_MC2_155 RHFAWRVLLVS-VLMAGGALGMFLWE----LRSGTSVETARTMAVNAIVA
Mb0433c|M.bovis_AF2122/97 RAVGIRG-----ATTAAAATVAWVMAGFTGLPRRAS---------TVALV
Rv0425c|M.tuberculosis_H37Rv RAVGIRG-----ATTAAAATVAWVMAGFTGLPRRAS---------TVALV
Mvan_1651|M.vanbaalenii_PYR-1 RAIGVRG-----AATTVGATSAWAMASMTGTPQRAS---------TVALI
TH_2876|M.thermoresistible__bu TAIPAISGRRRPNESDRGPTTSWPSASPTSVPVNVSCATDDDTFSSSAIR
MMAR_1228|M.marinum_M RAIGIRG-----ASTTTGAMLAWLMASATGTRRRAA---------TVALI
MAV_5219|M.avium_104 RQIVTRG-----AVTAAGATAAWAIGRWTPGTERRT--------ATMGLT
MUL_4826|M.ulcerans_Agy99 RQIANRG-----VVTAAGATAAWAIGRWTPGTERRT--------ATMGLT
MLBr_02671|M.leprae_Br4923 RQIVNRG-----VVTAAGATTAWAIGRWTPGTERRT--------ATMGLT
MAB_0962|M.abscessus_ATCC_1997 RRVMLSAIPSG-LTVGIATFLSYLLARQILHVSGNS--------TQASTA
..
Mflv_0956|M.gilvum_PYR-GCK YQVFNLLNVRSDTGSAFSRQ-TFTNGAIWVS----------------LAA
MSMEG_3926|M.smegmatis_MC2_155 AEMFYLLNNRFLLEPVLNRIGLFGNKIAFAT----------------VVA
Mb0433c|M.bovis_AF2122/97 A----LVAAQLGQTLVD-SHAWLVVLTALGS---------------LAAL
Rv0425c|M.tuberculosis_H37Rv A----LVAAQLGQTLVD-SHAWLVVLTALGS---------------LAAL
Mvan_1651|M.vanbaalenii_PYR-1 G----LVSTQLAQTLID-SRSPLVVATALGS---------------FATL
TH_2876|M.thermoresistible__bu GSAGRYMSMVSGPRVIS-APSIRIMRVRLGIPLGVRGDVRSERATAFDSA
MMAR_1228|M.marinum_M G----LVGTQLTQTVAD-SHGPLVVLTTVGS---------------FGVL
MAV_5219|M.avium_104 A----LVTTQLAQTLLTRRHSPLVVATALGS---------------AGVL
MUL_4826|M.ulcerans_Agy99 A----LVTTQLAQTLLTRSHSPLVLATAFGS---------------AGVL
MLBr_02671|M.leprae_Br4923 A----LVTTQLAQTLLTRRHSPLVVATALGS---------------AGVL
MAB_0962|M.abscessus_ATCC_1997 ALITELVAAVWVLAVVARPYQWWRVALVALSG---------------LGY
:
Mflv_0956|M.gilvum_PYR-GCK VIVLQVLVVQLDVLQNLFDTTELTSAQ-------WLFAIAVGSSVLVVDE
MSMEG_3926|M.smegmatis_MC2_155 CTALQLVFTYAPAMNAVFGSTPLGYVD-------WIKAAAVGAPVFGVVE
Mb0433c|M.bovis_AF2122/97 ATLISIP-----VVSQLLGCTPLDPLG-------WAQATAAATAATVAVA
Rv0425c|M.tuberculosis_H37Rv ATLISIP-----VVSQLLGCTPLDPLG-------WAQATAAATAATVAVA
Mvan_1651|M.vanbaalenii_PYR-1 AGVISTP-----GVSQVFGCTPVGPVG-------WGQAFSATAVAALLSA
TH_2876|M.thermoresistible__bu TEVLSDANHLFCSRTRGFGARVVAHIGGTRQALAWAQPLRHREAAAHERM
MMAR_1228|M.marinum_M AVVVTTP-----GLSHLFGCTPVGPLA-------WGQALLAAAVAGSASV
MAV_5219|M.avium_104 VGIVQTP-----VLSQFFGCTPLGPVA-------WTGVLGSTAGATAISA
MUL_4826|M.ulcerans_Agy99 IGIIQTP-----VVSHFFGCTPLGPVA-------WTGVFSATAGATAVSA
MLBr_02671|M.leprae_Br4923 IGIIQTP-----VISQFFGCTPLGPIA-------WSGVITATAGATAVSV
MAB_0962|M.abscessus_ATCC_1997 VAIFAIP---LARKAFMLDPGNLAVTG---------PALGIGIAAAAVIE
. :. : .
Mflv_0956|M.gilvum_PYR-GCK IGKAVVRT------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155 LEKFMVR-------------------------------------------
Mb0433c|M.bovis_AF2122/97 VLNRVLTGRDK---------------------------------SGQPNP
Rv0425c|M.tuberculosis_H37Rv VLNRVLTGRDK---------------------------------SGQPNP
Mvan_1651|M.vanbaalenii_PYR-1 TAPELLN------------------------------------------R
TH_2876|M.thermoresistible__bu VPREGPVGRDTRHSIRWGVRWGVRWGARSGGGGAGADRDHRTRLPGAGPR
MMAR_1228|M.marinum_M IAPELLM------------------------------------------R
MAV_5219|M.avium_104 LAP-----------------------------------------------
MUL_4826|M.ulcerans_Agy99 LAP-----------------------------------------------
MLBr_02671|M.leprae_Br4923 LAP-----------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 AVWWLQG-------------------------------------------
Mflv_0956|M.gilvum_PYR-GCK ---ARRRRRRRVSGADRPREARPASGR-----------------------
MSMEG_3926|M.smegmatis_MC2_155 -----RRKARAALAGEEPKGGHTAAHR-----------------------
Mb0433c|M.bovis_AF2122/97 QPPETDALSRDASPGAPPGPRRRRRATARRKAPVKAPSATRQTTKPKGPP
Rv0425c|M.tuberculosis_H37Rv QPPETDALSRDASPGAPPGPRRRRRATARRKAPVKAPSATRQTTKPKGPP
Mvan_1651|M.vanbaalenii_PYR-1 ATDAVRKRVADVVESVPVVDDDDAGLDEDGVEGADR------RRQQ----
TH_2876|M.thermoresistible__bu GARLRRPVAQQVPRRLPGQDRHQAGETLSGDRGGQRGGGRFHRRRAGRGH
MMAR_1228|M.marinum_M VSRQAQRLISVTADGQATVQEREAGAPT----------------------
MAV_5219|M.avium_104 -----NWLAKQVAALEPGQQDA----------------------------
MUL_4826|M.ulcerans_Agy99 -----KWLAKTVDVALEHQDWASGSA------------------------
MLBr_02671|M.leprae_Br4923 -----QWLNKAFGIAQLNQE------------------------------
MAB_0962|M.abscessus_ATCC_1997 -----KWSGQPRHFWATGDD------------------------------
Mflv_0956|M.gilvum_PYR-GCK -----------
MSMEG_3926|M.smegmatis_MC2_155 -----------
Mb0433c|M.bovis_AF2122/97 AHRSSSTYPRR
Rv0425c|M.tuberculosis_H37Rv AHRSSSTYPRR
Mvan_1651|M.vanbaalenii_PYR-1 --MDTGGD---
TH_2876|M.thermoresistible__bu IGRALGGDR--
MMAR_1228|M.marinum_M -----------
MAV_5219|M.avium_104 -----------
MUL_4826|M.ulcerans_Agy99 -----------
MLBr_02671|M.leprae_Br4923 -----------
MAB_0962|M.abscessus_ATCC_1997 -----------