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M. smegmatis MC2 155 MSMEG_2994 (-)

annotation: amidohydrolase family protein
coordinates: 3061057 - 3062286
length: 409

PSRILDFPVFDADNHFYEPKEALTKFLPDHRKGVIDYVDIRGRTKIVVRNHISDYIPNPTFEVVARPGAQ
EEYFRQGSGGKSYREVLGKPMKSIPAFRNPEARLEVMDGLGLDYTLMFPTLASLVEERLKDDPELIHDII
HALNEWMYETWQFDYEGRIFSTPVITLPIVDRALEELEWCLERGAKTVLVRPAPVPGFRGTRSFGTEEFD
PFWQACVKAGIPVAMHASDSGYAQYLNDWEPADEFLPFKPTAFRMVAMGKRPIEDTMTALVCHGTFTRNP
DLRILSIENGASWVPHLFHQFEDVYAKMPQDFPEEPIQAFKRCVYVAPFWEDNFKQMADLIGIDRVIFGS
DWPHPEGLADPINLVSDLQAHGLDDEGVRKVMGRNLVDLFQVENKVVYKPDVPALVIA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2994--100% (409)amidohydrolase family protein
M. smegmatis MC2 155MSMEG_4773-e-12353.91% (384) amidohydrolase family protein
M. smegmatis MC2 155MSMEG_2235-e-10547.55% (387) amidohydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3792-0.084.60% (409) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0299-1e-0825.67% (261) putative amidohydrolase (aminocarboxymuconate-semialdehyde
M. marinum MMMAR_3988-0.075.32% (393) metal-dependent hydrolase
M. avium 104MAV_1625-0.075.06% (401) amidohydrolase family protein
M. thermoresistible (build 8)TH_0536-0.084.56% (408) amidohydrolase family protein
M. ulcerans Agy99MUL_3849-0.075.06% (393) metal-dependent hydrolase
M. vanbaalenii PYR-1Mvan_2602-0.092.42% (409) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2994|M.smegmatis_MC2_155      MPSRILDFPVFDADNHFYEPKEALTKFLPDHRKGVIDYVDIRGRTKIVVR
Mvan_2602|M.vanbaalenii_PYR-1       MPSRILDYPVFDADNHFYEPKEALTKFLPDKRKGVIDYIDVHGRTKIMVR
Mflv_3792|M.gilvum_PYR-GCK          MPSRSLDYPVFDADNHFYEPKEALTQFLPDHRKGVIDYIDVHGRTKIVVR
TH_0536|M.thermoresistible__bu      MPSRELPYPVFDADNHFYEPQEALTKFLPEHRKGVIDYIDVRGRTKIVVR
MMAR_3988|M.marinum_M               MPSRELPFPVFDADNHMYEPQEALTKFLPDKRRHVIDYVQVRGRTKIVVR
MUL_3849|M.ulcerans_Agy99           MPSRELPFPVFDADNHMYEPQEALTKFLPDKRKHVIDYVQVRGRTKIVVR
MAV_1625|M.avium_104                MPSRELSFPVFDADNHMYEPQEALTKFLPDHRKHVIDYVQIRGRTKIVVR
MAB_0299|M.abscessus_ATCC_1997      -----MTSVRIDIHAHLWS-------------------------------
                                         :    :* . *::.                               

MSMEG_2994|M.smegmatis_MC2_155      NHISDYIPNPTFEVVARPGAQEEYFRQGSGGKSYREVLGKPMKSIPAFRN
Mvan_2602|M.vanbaalenii_PYR-1       NHISDYIPNPTFEVVARPGAQEEYFRHGSGGKSFREVMGKPMKAIPAFRN
Mflv_3792|M.gilvum_PYR-GCK          NHISDYIPNPTFEVVARPGAQEEYFKHGSGGKSFREVMGKPMKAIPAFRN
TH_0536|M.thermoresistible__bu      NQISDYIPNPTFEVVARPGAQEEYFKYGSGGKSFREVMGKPMKAIPAFRD
MMAR_3988|M.marinum_M               GQISDYIPNPTFEVVARPGAQEEYFRNGSRGKSYREVMGEPMKAIPAFRE
MUL_3849|M.ulcerans_Agy99           GQISDYIPNPTFEVVARPGAQEEHFRNGSGGKSYREVMGEPMKAIPAFRE
MAV_1625|M.avium_104                GHISEYIPNPTFEVVARPGAQEEYFRNGSGGKSYREILGEPMKAIPAFRE
MAB_0299|M.abscessus_ATCC_1997      ---DEYLS-----LLDGYGRPATDVHRGLGAGATRDDLDG----------
                                       .:*:.     ::   *     .: *  . : *: :.           

MSMEG_2994|M.smegmatis_MC2_155      PEARLEVMDGLGLDYTLMFPTLASLVEERLKDDPELIHDIIHALNEWMYE
Mvan_2602|M.vanbaalenii_PYR-1       PEARLEVMDGLGLDYTLMFPTLASLVEERLKDDPELIHDIIHALNEWMYE
Mflv_3792|M.gilvum_PYR-GCK          PEARLEVLDGLGLDYTIMFPTLASLVEERMKDDPDLILDIVHALNQWMYE
TH_0536|M.thermoresistible__bu      PEARLEVLDGLGLDYTIMFPTLASLVEERMKDDPDLILDVIHALNQWMYE
MMAR_3988|M.marinum_M               PGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQWMYE
MUL_3849|M.ulcerans_Agy99           PGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQWMYE
MAV_1625|M.avium_104                PGARLEVMDELGIDYALMFPTLASLVEERMKDDPEMTHDVIHALNQWMYE
MAB_0299|M.abscessus_ATCC_1997      ---RFELMDEAGVDLQILTATPAS---PHFEDQAAAVASARFIN--DEYA
                                       *:*::*  *:*  :: .* **    :::*:.    .  .      * 

MSMEG_2994|M.smegmatis_MC2_155      TWQFDYEGRIFSTPVITLPIVDRALEELEWCLERGAKTVLVRPAPVPGFR
Mvan_2602|M.vanbaalenii_PYR-1       TWQFDYEGRIFSTPVITLPIVDRALEELEWCLERGAKTVLVRPAPVPGFR
Mflv_3792|M.gilvum_PYR-GCK          TWQFDYQGRILSTPVINLSVVDRALEELQWCLERGARTVLVRPAPVPGYR
TH_0536|M.thermoresistible__bu      TWQFDYEGRILSTPVINLSVVDRALEELEWCLERGAKTILVRPAPVPGYR
MMAR_3988|M.marinum_M               TWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPVPGYR
MUL_3849|M.ulcerans_Agy99           TWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPVPGYR
MAV_1625|M.avium_104                QWSFNYKDRIFATPVITLPIVDRALEELEWCLERGARTVLVRPAPVPGYR
MAB_0299|M.abscessus_ATCC_1997      KLSSEYPGRFGALASLPLPHVPAALEELARAIDELGMYGASITTSVLG--
                                      . :* .*: : . : *. *  *****  .::. .      .:.* *  

MSMEG_2994|M.smegmatis_MC2_155      GTRSFGTEEFDPFWQACVKAGIPVAMHASDSGYAQYLNDWEPADEFLPFK
Mvan_2602|M.vanbaalenii_PYR-1       GTRSFGTEEFDPFWDACVKAGIPVAMHASDSGYAQYLNDWEPADEFLPFR
Mflv_3792|M.gilvum_PYR-GCK          GSRSLGLPEFDPFWDACVQAGIPVCMHASDSGYAQYLNDWEPADEFLPFR
TH_0536|M.thermoresistible__bu      GTRSLGLPEFDPFWDACVKAGIPVCMHASDSGYAQYLNDWEPADEFLPFR
MMAR_3988|M.marinum_M               GSRSFGFEEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGDEFLPFK
MUL_3849|M.ulcerans_Agy99           GSRSFGFKEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGDEFLPFK
MAV_1625|M.avium_104                GSRSFGFEEFDPFWQACVRAEIPVSMHASDSGYSELLNIWEPGDEFLPFK
MAB_0299|M.abscessus_ATCC_1997      --RSIADPIFDPLYAELNRRRAVLFVHPAGCGAESSL----ITDHSLTWS
                                      **:.   ***::    :    : :*.:..*  . *      *. *.: 

MSMEG_2994|M.smegmatis_MC2_155      PTAFRMVAMGKRPIED--TMTALVCHGTFTRNPDLRILSIENGASWVPHL
Mvan_2602|M.vanbaalenii_PYR-1       PTAFRMVAMGKRPIED--TMAALVCHGAFTRNPDLRILSIENGASWVPYL
Mflv_3792|M.gilvum_PYR-GCK          PTAFRMVAMGKRPIED--TMAALVCHGALTRNPDLRILSIENGASWVPYL
TH_0536|M.thermoresistible__bu      PTAFRMVAMGKRPIED--TMAALVCHGALSRNPDLRILSVENGASWVPYL
MMAR_3988|M.marinum_M               PTAFRMLAMGKRPIED--AMGALVCHGALSRNPELRILSIENGADWVPTL
MUL_3849|M.ulcerans_Agy99           PTAFRMLAMSKRPIED--AMGALVCHGALSRNPELRILSIKNGADWVPTL
MAV_1625|M.avium_104                PTAFRSLAMGHRPVED--AFGALICHGALSRNPDLRILSIENGADWVPHL
MAB_0299|M.abscessus_ATCC_1997      --------IG-APIEDTVAIMHLIVAGVPSRYPDMKIVTCHLGGALPMVL
                                            :.  *:**  ::  *:  *. :* *:::*:: . *.     *

MSMEG_2994|M.smegmatis_MC2_155      FHQFEDVYAKMPQDFPEEPIQAFKRCVYVAPFWEDN--FKQMADLIGIDR
Mvan_2602|M.vanbaalenii_PYR-1       FYQFKDVYSKMPQEFPEDPIEAFRRCVYVAPFWEDD--FKKMADLCGIDR
Mflv_3792|M.gilvum_PYR-GCK          FYQFEDVYKKMPQEFPENPIDAFRRGVYVAPFWEDD--FGKMADLLGIDR
TH_0536|M.thermoresistible__bu      FYQFKDVYKKMPQEFAEDPIEAFKRCVYVAPFWEDN--FKEIADLIGIDR
MMAR_3988|M.marinum_M               FKGLKGVYKKMPNAFMEDPIEAFKRCVYISPFWEDR--FAEIVKMVGTDR
MUL_3849|M.ulcerans_Agy99           FKGLKGVYKKMPNAFMEDPIEAFKRCVYISPFWEDR--FVEIVKMVGTDR
MAV_1625|M.avium_104                FKGLKGVYKKMPQAFAEDPIETFKRCVYVSPFWEDR--FAEIVNMVGTDR
MAB_0299|M.abscessus_ATCC_1997      ERAHRQVTEWEATQCPEAPRDAARRLWYDTVGHDHTPALRAAVASLGVDR
                                        . *    .    * * :: :*  * :   :.   :   .   * **

MSMEG_2994|M.smegmatis_MC2_155      VIFGSDWPHPEGLADPINLVSDLQAHGLDDEGVRKVMGRNLVDLFQVENK
Mvan_2602|M.vanbaalenii_PYR-1       VIFGSDWPHPEGLADPINLVADLEAHGLDQEGVRKVMGKNMVDLFRVENK
Mflv_3792|M.gilvum_PYR-GCK          VIFGSDWPHPEGLADPITLVDQLEENGLDEDGIRKVMGGNLVDLFKVPNK
TH_0536|M.thermoresistible__bu      VIFGSDWPHPEGLADPIRLVDELEEHGLDDEGIRKVMGANLIELFGVENK
MMAR_3988|M.marinum_M               VVFGSDWPHPEGLKDPISFVDELAG--FPPEDVAKIMGGNMMEVMKIGTP
MUL_3849|M.ulcerans_Agy99           VVFGSDWPHPEGLKDPISFVDELAG--FPPEDVAKIMGGNMMDVMKIGTA
MAV_1625|M.avium_104                VVFGSDWPHPEGLKDPISFVDELAD--FSDEDKAKIMGGNLMKLMKVSAP
MAB_0299|M.abscessus_ATCC_1997      LIFGSDFPYQAGPRYVSSATYIEEG--LSAEDASAILDHNGAELLGLTGV
                                    ::****:*:  *       .       :  :.   ::. *  .:: :   

MSMEG_2994|M.smegmatis_MC2_155      VVYKPDVPALVIA-
Mvan_2602|M.vanbaalenii_PYR-1       VVYKPDVPALVIA-
Mflv_3792|M.gilvum_PYR-GCK          VVHKPDAPALVIA-
TH_0536|M.thermoresistible__bu      KVHNPNVPALEIPA
MMAR_3988|M.marinum_M               AP-QPVNA------
MUL_3849|M.ulcerans_Agy99           AP-KPVNA------
MAV_1625|M.avium_104                AAKKPVSA------
MAB_0299|M.abscessus_ATCC_1997      --------------