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M. thermoresistible (build 8) TH_2768 (-)

annotation: phosphonate metabolism protein PhnI
coordinates: 4110082 - 4111143
length: 354

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2768--100% (354)phosphonate metabolism protein PhnI
M. thermoresistible (build 8)TH_3619-6e-0532.87% (143) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4039infB4e-0527.78% (162) translation initiation factor IF-2
M. tuberculosis H37RvRv3881c-8e-0529.56% (159) hypothetical protein Rv3881c
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4665rpfA2e-0537.50% (88) resuscitation-promoting factor RpfA
M. avium 104MAV_1722-2e-0639.73% (73) secreted protein
M. smegmatis MC2 155MSMEG_4787-5e-0536.67% (90) virulence factor mce family protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5871-1e-12266.57% (338) phosphonate metabolism protein PhnI

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4039|M.gilvum_PYR-GCK          MAGKARVHELAKELGVTSKEVLARLGEQGEFVKSASSTVEAPVARRLRES
MAV_1722|M.avium_104                MG------------------------------------------------
TH_2768|M.thermoresistible__bu      -------------------------------------------------M
Mvan_5871|M.vanbaalenii_PYR-1       -------------------------------------------------M
MMAR_4665|M.marinum_M               ------------------------------------------MSGRHRKP
Rv3881c|M.tuberculosis_H37Rv        MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLV
MSMEG_4787|M.smegmatis_MC2_155      --------MNRKRIAKGLAVGLVVLLVAGAAVLVRQVFLAPRTFQALFTS
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          FGGNKPDAVKPAAGASNGAPAKPSAPGARPGPRPGPPAPAQPKEPPAPAA
MAV_1722|M.avium_104                FDPN-----VPAAG-------------------PAPDAPP----PPAPDA
TH_2768|M.thermoresistible__bu      YATMRETAGLEAAR---------ALVTHRPGGGERTDTSLLEEQLCAEAG
Mvan_5871|M.vanbaalenii_PYR-1       YASMHENEALDAAR---------AIAQSTRRGND-ISTAVLEEQICAEAG
MMAR_4665|M.marinum_M               TTSNVSVAKIAFTG-----AVLGGGGIALAGHAAAATDGEWDQVARCESG
Rv3881c|M.tuberculosis_H37Rv        LSADNMREYLAAGAK-------ERQRLATSLRNAAKAYGEVDEEAATALD
MSMEG_4787|M.smegmatis_MC2_155      ATGIYPGDDVRVSG-----VKVGTIEAITPEGTQTRLTLKVDRGVPIPAD
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          PAAAAPAPAAPAP--PAAPPAPAASAAPPSAPEAPSARPTPGPRPGPGGP
MAV_1722|M.avium_104                P--PAPAPDAPPA--PDAPPPPAPDAPPPPAPDAP-------PAPGPDVP
TH_2768|M.thermoresistible__bu      LWEPAVARRALHQ--SRGDIAHAVSMLRVWAATQP-HVAAAAVRPDDVVV
Mvan_5871|M.vanbaalenii_PYR-1       LWEPAAARRALDQ--AHGDPAHAVSILRVWAATQP-HLHALTVQPEDVVL
MMAR_4665|M.marinum_M               GNWAINTGNGYYGGVQFAQSTWASHGGGEYAPSAQLASREEQIAVAERVL
Rv3881c|M.tuberculosis_H37Rv        NDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEP---NFMDLKEAARKL
MSMEG_4787|M.smegmatis_MC2_155      AKAVIVAQNLVAARYVQLAPAYRSEGPTLPDDAVIGLDRTAVPVEWDEVK
                                          .             .                             

Mflv_4039|M.gilvum_PYR-GCK          KPGAPKPAPRTPRVGNNPFSSQQPVERPAPRPQGPAGPGGPRPGPGAGGP
MAV_1722|M.avium_104                PP----PAPKAYSVNWDAIAQCE---------------------------
TH_2768|M.thermoresistible__bu      LRRLSSAYPQIPGGQWLGAAPELMP-------------------------
Mvan_5871|M.vanbaalenii_PYR-1       TRRLSSAYPQIPGGQWLGFAPELIA-------------------------
MMAR_4665|M.marinum_M               ATQGRGAWPVCGHGLSAATPRDVPAP------------------------
Rv3881c|M.tuberculosis_H37Rv        ETGDQGASLAHFADGWNTFNLTLQGDVKR---------------------
MSMEG_4787|M.smegmatis_MC2_155      EQLTRLATELGPRSGVDGTSMAR---------------------------
                                          .                                           

Mflv_4039|M.gilvum_PYR-GCK          RPGGGPRPGATPGNMPPRPVGGPRPGGGPRPGGGPRPGAGPRPTPGGAGR
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      --------------------------------------------------
Mvan_5871|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4665|M.marinum_M               --------------------------------------------------
Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4787|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          PGGGGGGNYRGGGAGGGGGAGGAAAGGFRGRPGGGGGRPGQRGGAAGAFG
MAV_1722|M.avium_104                ----SGGNW--GINTGNGYAGGLQFTSSTWHANGGSGSP-----------
TH_2768|M.thermoresistible__bu      ----RELDWS-QPAPGDGPAAPEPPEQPPGPGPDAKPPTR----------
Mvan_5871|M.vanbaalenii_PYR-1       ----RQLDWTPTPDVSDSPPAAADQDPLTADAPAADAPRR----------
MMAR_4665|M.marinum_M               ----AALDAPLDAPGINGEPAPLAPPPGDDVPPPADPAPP----------
Rv3881c|M.tuberculosis_H37Rv        ---FRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLH
MSMEG_4787|M.smegmatis_MC2_155      -----FIETTADAMEGNGEKLRNTISQLSGVARILAEGSGNIVDIIKNLQ
                                           :                                          

Mflv_4039|M.gilvum_PYR-GCK          RPGGAPKRGRKSKRAKRAEYENMQAPVVGGVRLPHGNGETIRLARGASLS
MAV_1722|M.avium_104                --AGASRE------------------------------EQIRVAENVLHS
TH_2768|M.thermoresistible__bu      --AGTPRVR-----------------------------DLIDGVAMRRPP
Mvan_5871|M.vanbaalenii_PYR-1       --VETLRVR-----------------------------DLIQGAPTVTPP
MMAR_4665|M.marinum_M               VELAANDVPAP---------------------------ADLPPAPEDLPP
Rv3881c|M.tuberculosis_H37Rv        VWARREHPT----------------------------YEDIVGLERLYAE
MSMEG_4787|M.smegmatis_MC2_155      TFVTALRDS----------------------------NQQVVAFQNRLAT
                                                                            :         

Mflv_4039|M.gilvum_PYR-GCK          DFADKINANPASLVQALFNLGEMVTATQSVNDETLELLGGEMNYVVQVVS
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      --------------------------------------------------
Mvan_5871|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4665|M.marinum_M               --------------------------------------------------
Rv3881c|M.tuberculosis_H37Rv        N-------------------------------------------------
MSMEG_4787|M.smegmatis_MC2_155      LTSVVD--------------------------------------------
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          PEDEDRELLQSFDLSYGEDEGGEDDLEFRPPVVTVMGHVDHGKTRLLDTI
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      --------------------------------------------------
Mvan_5871|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4665|M.marinum_M               --------------------------------------------------
Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4787|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          RDATVREGEAGGITQHIGAYQVTVDLDGNERPITFIDTPGHEAFTAMRAR
MAV_1722|M.avium_104                --------------QGIGAWPVCG------------------------RR
TH_2768|M.thermoresistible__bu      -------------VDGDGADPAATVP----------------------AP
Mvan_5871|M.vanbaalenii_PYR-1       -------------ADGAGDDPARAVL----------------------VP
MMAR_4665|M.marinum_M               -------------APEDLAPPAPADLP--------------------PAP
Rv3881c|M.tuberculosis_H37Rv        ------------PSARDQILPVYAEYQQRSEKVLTEYNNKAALEPVNPPK
MSMEG_4787|M.smegmatis_MC2_155      ------------GSRSDLDAALKNLSVAVGEVQRFVAGSRNQTSEQIQRL
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          GAKATDIAILVVAADDGVMPQTVEAVNHAQAADVPIVVAVNKIDKEGADP
MAV_1722|M.avium_104                G-------------------------------------------------
TH_2768|M.thermoresistible__bu      PYPRAAVLALLARGETGALVALAALILGRRSEAVLVELTVGVAGVRVPHP
Mvan_5871|M.vanbaalenii_PYR-1       PHSRPNRLALLTRGETGALVALAAMILGRRQEAVLVELSVAVATVRIHHP
MMAR_4665|M.marinum_M               EDLPPAPQDLPPAPEDVAAPAPADLPPAPEDVAPPVELVGNDVPAPVDLP
Rv3881c|M.tuberculosis_H37Rv        PPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPPTGSP
MSMEG_4787|M.smegmatis_MC2_155      ADVTSNLVDQRLQVENLLHIAPNAFVNGYNIYNPDSGSPVGQFVFHNMSE
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          AKIRGQLTEYGLVPEEYGGDTMFVDISAKAGTNIEALLEAVVLTADASLD
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      R-------------------------TGVPCLAAEVPVTEVEVVLDAEVD
Mvan_5871|M.vanbaalenii_PYR-1       R-------------------------SGIPVAVVELPITEVEVVLDAEVE
MMAR_4665|M.marinum_M               P-----------------------APEDLPPAPEDLAPPAPADLPPAPED
Rv3881c|M.tuberculosis_H37Rv        G-------------------------GGLPADTAAQLTSAGREAAALSGD
MSMEG_4787|M.smegmatis_MC2_155      P--------------------LHFICGAIGAVENVTAPETAKLCAQYLGP
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          LRANPDMEAQGVAIEAHLDRGRGPVATVLIQRGTLRVGDSVVAGDAYGRV
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      GRPGLATGWG------------ASLGTVERRAIALALLDAAMQADR----
Mvan_5871|M.vanbaalenii_PYR-1       GRPGLALGWG------------ATLGTVERRAIALALLDAAILADG----
MMAR_4665|M.marinum_M               LAPPAPADLP-----------PAPEDLAPPAPADLPPAPEDLAPPAP---
Rv3881c|M.tuberculosis_H37Rv        VAVKAASLGG------------GGGGGVPSAPLGSAIGGAESVRPAG---
MSMEG_4787|M.smegmatis_MC2_155      ALRLLNFNNVPFPVSPYLMPSANPENLIYSEPNLAPGAGGGSPQPPETPP
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          RRMVDEHGEDVEEALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQIADR
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      ---------ELREPLLLDPQTVLAATDGPATNGFVEHLRLPHYAGFTAYL
Mvan_5871|M.vanbaalenii_PYR-1       ---------DLAEPLTLDEQTIIAATDGPATNGFVEHLRLPHYAGFTAYL
MMAR_4665|M.marinum_M               --------ADLPPAPEDLPPAPEDLPPPADADNPPVDVHEASTVAYTKKL
Rv3881c|M.tuberculosis_H37Rv        -----------AGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQGQGGAKS
MSMEG_4787|M.smegmatis_MC2_155      VLSAYNPGPPPPPPFTGRPPGTPPPGAAQLLPGAPPIVPPNVPSSVRDML
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          RSARKRNALAARTRKRISLEDLDSALKETSQLNLILKGDNSGTVEALEEA
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      ARAVPDPTTPMTESRMREAP------------------------------
Mvan_5871|M.vanbaalenii_PYR-1       SQAASK------EQR-----------------------------------
MMAR_4665|M.marinum_M               WQAIVGQNISGNDALDALAQPTVFA-------------------------
Rv3881c|M.tuberculosis_H37Rv        KGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK----------------
MSMEG_4787|M.smegmatis_MC2_155      APAGPPPGPVPETGPAPGPLPAEAPLEPAEGTPPA---------------
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          LLGIQVDDEVQLRVIDRGVGGVTETNVNLASASDAIIIGFNVRAEGKATE
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      --------------------------------------------------
Mvan_5871|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4665|M.marinum_M               --------------------------------------------------
Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4787|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          LANREGVEIRYYSIIYQAIDEIESALKGMLKPIYEEKELGRAEIRAIFRS
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      --------------------------------------------------
Mvan_5871|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4665|M.marinum_M               --------------------------------------------------
Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4787|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          SKVGNIAGCLVQSGIMRRNAKARLLRDNVVVAQNLTVSSLKREKDDATEV
MAV_1722|M.avium_104                --------------------------------------------------
TH_2768|M.thermoresistible__bu      --------------------------------------------------
Mvan_5871|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_4665|M.marinum_M               --------------------------------------------------
Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4787|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_4039|M.gilvum_PYR-GCK          REGYECGLTLTYNDIKEGDVIETYELVEKART
MAV_1722|M.avium_104                --------------------------------
TH_2768|M.thermoresistible__bu      --------------------------------
Mvan_5871|M.vanbaalenii_PYR-1       --------------------------------
MMAR_4665|M.marinum_M               --------------------------------
Rv3881c|M.tuberculosis_H37Rv        --------------------------------
MSMEG_4787|M.smegmatis_MC2_155      --------------------------------