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M. tuberculosis H37Rv Rv3881c (-)

annotation: CONSERVED HYPOTHETICAL ALANINE AND GLYCINE RICH PROTEIN
coordinates: 4360543 - 4361925
length: 460

TQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLA
TSLRNAAKAYGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLE
TGDQGASLAHFADGWNTFNLTLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQY
VAQLHVWARREHPTYEDIVGLERLYAENPSARDQILPVYAEYQQRSEKVLTEYNNKAALEPVNPPKPPPA
IKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPPTGSPGGGLPADTAAQLTSAGREAAALSG
DVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQGQ
GGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3881c--100% (460)CONSERVED HYPOTHETICAL ALANINE AND GLYCINE RICH PROTEIN
M. tuberculosis H37RvRv2487cPE_PGRS423e-1031.01% (158) PE-PGRS family protein
M. tuberculosis H37RvRv2839cinfB1e-0929.50% (200) translation initiation factor IF-2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3911c-0.098.70% (460) hypothetical protein Mb3911c
M. gilvum PYR-GCKMflv_0757-5e-3931.17% (539) hypothetical protein Mflv_0757
M. leprae Br4923MLBr_01556infB4e-1029.35% (184) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_3131c-3e-0730.81% (172) translation initiation factor IF-2 (InfB)
M. marinum MMMAR_5457espB1e-17768.53% (464) ESX-1 secreted protein, EspB
M. avium 104MAV_4827-1e-0929.78% (178) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0076-5e-4730.81% (516) antigen MTB48
M. thermoresistible (build 8)TH_2612-3e-3031.65% (297) PUTATIVE putative hypothetical protein Mjls_0066
M. ulcerans Agy99MUL_2550-2e-7039.47% (489) hypothetical protein MUL_2550
M. vanbaalenii PYR-1Mvan_0090-2e-2726.47% (529) hypothetical protein Mvan_0090

CLUSTAL 2.0.9 multiple sequence alignment


Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3911c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_5457|M.marinum_M               --------------------------------------------------
MUL_2550|M.ulcerans_Agy99           --------------------------------------------------
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0090|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0076|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES
MAB_3131c|M.abscessus_ATCC_199      MAGKARVHELAKELGVTSKEVLARLSDQGEFVKSASSTVEAPVARRLRES
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3911c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_5457|M.marinum_M               --------------------------------------------------
MUL_2550|M.ulcerans_Agy99           --------------------------------------------------
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0090|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0076|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP
MAB_3131c|M.abscessus_ATCC_199      FGGGDKPAPAASNGAAAEAAAP-------------PKKAGPKPGAPKPAP
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3911c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_5457|M.marinum_M               --------------------------------------------------
MUL_2550|M.ulcerans_Agy99           --------------------------------------------------
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0090|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0076|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          VQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA
MAB_3131c|M.abscessus_ATCC_199      KKVAEPVVEAPVAP-EPPAAPAAPAAPAPKPSPAARPAAAEAAAPAPAPA
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3911c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_5457|M.marinum_M               --------------------------------------------------
MUL_2550|M.ulcerans_Agy99           --------------------------------------------------
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0090|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0076|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          PHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRP
MAB_3131c|M.abscessus_ATCC_199      PAP-RPGATPGPKPG-AP----RVPRVGNNPFSSAQPAERPAPRPQAPRP
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3911c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_5457|M.marinum_M               --------------------------------------------------
MUL_2550|M.ulcerans_Agy99           --------------------------------------------------
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0090|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0076|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ------SASPSSMSPRPGGAVGGGGPRPPRTG-VPRPGGGRPGAPVGGRS
MAB_3131c|M.abscessus_ATCC_199      GAPRPGGASPSNMPPRP--SPGSMGPRPPRPGGGPRPGGGPRPGGAGRPG
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        -------------------------MTQSQTVTVDQQEILNRANEVEAP-
Mb3911c|M.bovis_AF2122/97           -------------------------MTQSQTVTVDQQEILNRANEVEAP-
MMAR_5457|M.marinum_M               -------------------------MSQPQTVTVDQQEILNRADEVEAP-
MUL_2550|M.ulcerans_Agy99           -------------------------MTLAQVLAVEGEELLARAVRLEAP-
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          --------------------------MADGELKVDPNDLTTKAATVEGIP
Mvan_0090|M.vanbaalenii_PYR-1       --------------------------MAD-ELKVDPDDLDTKAGTVEAIP
MSMEG_0076|M.smegmatis_MC2_155      ---------------------------MSEELQYELPGLERKAHECEST-
MLBr_01556|M.leprae_Br4923          DAGGGNYRGGGVG-ALPGGGS----GGFRGRPGGGGHGGGGRPGQRGGAA
MAB_3131c|M.abscessus_ATCC_199      GGGGGNYRGGGTGTGAPAGGPPGAGGGFRGRPGGG--GGGGRPGQRGGAA
MAV_4827|M.avium_104                -------------------------MNIVLGVSMAPSSIQMVVLEGEYAD
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        -MADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLAT-
Mb3911c|M.bovis_AF2122/97           -MADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLAT-
MMAR_5457|M.marinum_M               -MATPPTDVPQAPSGLTAANNAAEQLAVSADNVRLYLQAGERERQRLAT-
MUL_2550|M.ulcerans_Agy99           -IPGLPTEDPQPPCDFAPAKEAAAELARSAGEMRKYLGYFDTERARLAQ-
TH_2612|M.thermoresistible__bu      ----MPTD-PQPACGLELAGIAVSQLYAASAETRAKIAAGEVEARRLSQ-
Mflv_0757|M.gilvum_PYR-GCK          WGSDPAAVPLSDPDKLSSTTASVQNLVKNATALGAEQKWGQAESRRLAE-
Mvan_0090|M.vanbaalenii_PYR-1       WGEDPSAVAVADPDKLTPTTASVRNLIKNAEALGAEQRWGIAESRRLAE-
MSMEG_0076|M.smegmatis_MC2_155      --RPEGPGDATKPDELATTASVYSKLMASAAKLKATFAAGDREGERIAA-
MLBr_01556|M.leprae_Br4923          GAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARG
MAB_3131c|M.abscessus_ATCC_199      GAFGRPGGAPKRGRKSKRAKRAEYENMQAPVVGGVRLPHGNGEVIRLARG
MAV_4827|M.avium_104                GATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIG--
                                                                              :   :.  

Rv3881c|M.tuberculosis_H37Rv        ----------------------SLRNAAKAYGEVDEEAATALDNDGEGTV
Mb3911c|M.bovis_AF2122/97           ----------------------SLRNAAKAYGEVDEEAATALDNDGEGTV
MMAR_5457|M.marinum_M               ----------------------SLRNAAAAYGEVEDESATALDNDGNGEV
MUL_2550|M.ulcerans_Agy99           ----------------------SLRNAAKAYEEVDEHAAADLDT-GSASV
TH_2612|M.thermoresistible__bu      ----------------------SLVAAANAYTEFDARAKAALDAGEPIPS
Mflv_0757|M.gilvum_PYR-GCK          ----------------------TLRLVAKAYQDVDEASSSNIDATIPGGA
Mvan_0090|M.vanbaalenii_PYR-1       ----------------------TLRLVAQAYRAVDEASAGNIDSTMPGGT
MSMEG_0076|M.smegmatis_MC2_155      ----------------------AIRAAAGAYQKIEEQKAAELSRQMNGSD
MLBr_01556|M.leprae_Br4923          ASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNV
MAB_3131c|M.abscessus_ATCC_199      ASLSDFAEKIDANPASLVQALFNLGEMVTATQSVGDETLELLGGEMNYVV
MAV_4827|M.avium_104                ---------------------VTWTDQLEAAALRDALAARRIDNVMLVSA
                                                                 *           :.       

Rv3881c|M.tuberculosis_H37Rv        QAESA---------------GAVGGDSSAELTDTPRVATAGEPN------
Mb3911c|M.bovis_AF2122/97           QAESA---------------GAVGGDSSAELTDTPRVATAGEPN------
MMAR_5457|M.marinum_M               DAQSA---------------GGAGAGQTESLEETPKVAAAGESD------
MUL_2550|M.ulcerans_Agy99           SAANP---------------GPAGAEPETEAFDDAGVSTMAADHRL--DG
TH_2612|M.thermoresistible__bu      EPVFP---------------RYDIEPPAPEPTGLPIGQCPGPPG------
Mflv_0757|M.gilvum_PYR-GCK          SVSAP---------------APIPIGLNATPPPPVPQPMEPFGYVSDNDG
Mvan_0090|M.vanbaalenii_PYR-1       SSPAP---------------APVPIPPNSVPAPPPPPPMPGFENVAADGD
MSMEG_0076|M.smegmatis_MC2_155      APPPA---------------AEAVVPDMSGIPGPLAIPSMEYPSAAAAAD
MLBr_01556|M.leprae_Br4923          QVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRL
MAB_3131c|M.abscessus_ATCC_199      QVVSPEDEDRELLESFDLTYGEDEGGEEDLRTRPPVVTVMGHVDHGKTRL
MAV_4827|M.avium_104                FLAAAALAQNVG--------GAMGYERTAVLLVEPDTATLAVVETS-DGS
                                        .                                             

Rv3881c|M.tuberculosis_H37Rv        FMDLKEAARKLETGD-QGASLAHFADGWNTFNLT-----LQGDVKRFRGF
Mb3911c|M.bovis_AF2122/97           FMDLKEAARKLETGD-QGASLAHFADGWNTFNLT-----LQGDVKRFRGF
MMAR_5457|M.marinum_M               FTDLKTAATKLESGD-QGTSMVNFADGWNNFNLS-----LQRDIKRFRIF
MUL_2550|M.ulcerans_Agy99           YADLKVRALTIEWAD-NGNSFENFARTWLDYRLK-----LLEATDRFGPF
TH_2612|M.thermoresistible__bu      YLDVKTAAAQINAPD-QTASLQEFAANWRAYSTQ-----LSERANSFNLD
Mflv_0757|M.gilvum_PYR-GCK          SLDPIQTDKKLAEGD-QGASLRAAATEWTANAAR-----LTEAAIPFEVR
Mvan_0090|M.vanbaalenii_PYR-1       ILDPIETDNKLLEGD-QAAALRAAAARWSANAVR-----LADASAPFEIK
MSMEG_0076|M.smegmatis_MC2_155      EMDWEAAARIIHSGDTQALSMKYFRDQWRDYQST-----LEGHGRHFANP
MLBr_01556|M.leprae_Br4923          LDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTA
MAB_3131c|M.abscessus_ATCC_199      LDTIRKANVREGEAGGITQHIGAYQVAVEHDGTERPITFIDTPGHEAFTA
MAV_4827|M.avium_104                IPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPL
                                                  .     :                  :          

Rv3881c|M.tuberculosis_H37Rv        DN-WEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARRE
Mb3911c|M.bovis_AF2122/97           DN-WEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARRE
MMAR_5457|M.marinum_M               EN-WEGDAATACEASMDQQKEWILHMAKLSASLAKQANFMAQLQLWARRG
MUL_2550|M.ulcerans_Agy99           QR-WDGEAAAAVEDHFDRQIAWLRQMADLCSTMASQAQTVAAAQRQLHAS
TH_2612|M.thermoresistible__bu      DVNWGGTGAESAQDAMTEHRQWLQAMAGVAENLADHAEKLADAHRKAVQE
Mflv_0757|M.gilvum_PYR-GCK          MQNWEGVAAEAAYTKLKSFGGWLQALAGKWNQLAAEAEKLATAHDQAKAA
Mvan_0090|M.vanbaalenii_PYR-1       IQNWEGVAAEAAYIKFKSFGGWLQTLAGKWTQLAAEAEKLAAAHDQAKAA
MSMEG_0076|M.smegmatis_MC2_155      AEGWAGAAAETCAEAQRRLSTWWADMGAECGRLAQEATTFVDAHDKLVAN
MLBr_01556|M.leprae_Br4923          MRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKE
MAB_3131c|M.abscessus_ATCC_199      MRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKE
MAV_4827|M.avium_104                KQVLQTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPG
                                                                            .         

Rv3881c|M.tuberculosis_H37Rv        HP-------TYEDIVGLERLYAENPSA--------RDQILPVYAEYQQRS
Mb3911c|M.bovis_AF2122/97           HP-------TYEDIVGLERLYAENPSA--------RDQILPVYAEYQQRS
MMAR_5457|M.marinum_M               HP-------TLADIVELERL-AKDPDY--------QEQAIKLYAEYQETS
MUL_2550|M.ulcerans_Agy99           HIQFQGKTVRFADLRDLDDLYCSVPKADVT---NMRNQILAIYAVLQQTS
TH_2612|M.thermoresistible__bu      HP-------TEEEVERVENIVRQNFRW------------MDMYHQLQRKS
Mflv_0757|M.gilvum_PYR-GCK          NAP------IRIEFEALQSEFVKQGMA-------ASQASRDRLQQLYRES
Mvan_0090|M.vanbaalenii_PYR-1       NAP------VRAQYEALQTQLMTTSMDG-----GAQRAVQLQMEQLYQES
MSMEG_0076|M.smegmatis_MC2_155      HPT------LENVREFEETEWASEWDR------------QNAWAMLQEQS
MLBr_01556|M.leprae_Br4923          GADPAKIRGQLTEYGLVAEDFGGDTMFIDISA-KVGTNIEALLEAVLLTA
MAB_3131c|M.abscessus_ATCC_199      GADPAKIRAQLTEYNLVAEDFGGDTMFVDISA-RQGTNIEQLLEAVLLTA
MAV_4827|M.avium_104                TGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPE
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        EK---------VLTEYNNKA------------------------------
Mb3911c|M.bovis_AF2122/97           EK---------VLTEYNNKA------------------------------
MMAR_5457|M.marinum_M               EK---------VLSEYNTKA------------------------------
MUL_2550|M.ulcerans_Agy99           DE---------ELAEYEPAAN-----------------------------
TH_2612|M.thermoresistible__bu      DE---------VLSEYAKDS------------------------------
Mflv_0757|M.gilvum_PYR-GCK          EA---------VREIYANGGRPTPVQPPQPRPDSVAPTSPVTANGDPRDR
Mvan_0090|M.vanbaalenii_PYR-1       EA---------IRETYAKAGQPTPVQPPQPRPDAVAPAAPVTGNGDPNRR
MSMEG_0076|M.smegmatis_MC2_155      ED---------ALEAYANGSQIQEIRPGKP----------------PSIG
MLBr_01556|M.leprae_Br4923          DA---------ALDLRANSGMEAQGVAIEAHLDR----GRGPVATVLVQR
MAB_3131c|M.abscessus_ATCC_199      DA---------ALDLRANPDMEAQGVAIEAHLDR----GRGPVATVLIQR
MAV_4827|M.avium_104                DSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQH
                                    :                                                 

Rv3881c|M.tuberculosis_H37Rv        ---------------------------------ALEPVNPPKPPPAIKID
Mb3911c|M.bovis_AF2122/97           ---------------------------------ALEPVNPPKPPPRHQDR
MMAR_5457|M.marinum_M               ---------------------------------DLEPVNPPKPPAAIKID
MUL_2550|M.ulcerans_Agy99           --------------------------------FPLPPVQPTKPPKANEVK
TH_2612|M.thermoresistible__bu      --------------------------------------------ALSGIE
Mflv_0757|M.gilvum_PYR-GCK          GVPARTEDEERRDPWGAGEQPNAQGGGAPSGGEPQQPQTPQEAPVSPP-V
Mvan_0090|M.vanbaalenii_PYR-1       GMPAHTEEESRRGGGSGAGQPSGSGGQQPGG----QPQIPQEAPVSPMSA
MSMEG_0076|M.smegmatis_MC2_155      GLPAVNDGDVQASPTSAPGGPGGPGSGTPGGGGAGGGGGTPEMPELPSTD
MLBr_01556|M.leprae_Br4923          GTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAG
MAB_3131c|M.abscessus_ATCC_199      GTLRVGDSIVAGDAYGRVRRMVDEHGEDVEEALPSRPVQVIGFTSVPGAG
MAV_4827|M.avium_104                LIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPA
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        PPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPP------TGSPGG
Mb3911c|M.bovis_AF2122/97           PAPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPP------TGSPGG
MMAR_5457|M.marinum_M               PPPPAQPQGLIPGFLMPPGDGS-TGLASGMTP-PMIPP------TGG-AG
MUL_2550|M.ulcerans_Agy99           IDPPAQAKPPEQ-IVVPPGPDPVPAPADDWPVDEALPNP--TDMPVVPFA
TH_2612|M.thermoresistible__bu      VPPPPTGAAMVPPVTTNGDPRGRYSRDADLKAKYIQEG------------
Mflv_0757|M.gilvum_PYR-GCK          AEQPPQATQQSGQQESSPAGGQQGGGQQGGAPGGSPGGS---PGGGSPGG
Mvan_0090|M.vanbaalenii_PYR-1       AEQAAQGAQQAAPQGGSQGGSPGGGSQGDGSQGGSPAGG---SQGGAPGG
MSMEG_0076|M.smegmatis_MC2_155      PSMSPMSANSAGEEQSS-GSPSSGGSPSGSPSGGSPSGGGAPSGAGMPDG
MLBr_01556|M.leprae_Br4923          DNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQL
MAB_3131c|M.abscessus_ATCC_199      DNLLVVDEDRIARQIADRRSARKRNALAARSRKRISLDDLDAALKETSQL
MAV_4827|M.avium_104                APPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPR
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        GLPADTAAQLTS--AGREAAA-LSGDVA-VKAASLGGGGGGGVPSAPLG-
Mb3911c|M.bovis_AF2122/97           GLPADTAAQLTS--AGREAAA-LSGDVA-VKAASLGGGGGGGVPSAPLG-
MMAR_5457|M.marinum_M               GTPDVNTAELTS--AGREAASNLSKGLG-VKPMSLGGGGGG-LGGMPMGD
MUL_2550|M.ulcerans_Agy99           GSPQLPGNTLADSFAGRGGGTGLSAGAPKLKPASFGG-AGAASMRPPIGP
TH_2612|M.thermoresistible__bu      -------------------------------APGGGGAPGGGAXRIRVG-
Mflv_0757|M.gilvum_PYR-GCK          GMPTTGKGTEPRLP--TDPSLKPAAAGGGSSGG-GGGGGGVPAGPLQPAV
Mvan_0090|M.vanbaalenii_PYR-1       GMPGLGKG-EPKLP--TDPSLRPAAAGGGGSGG-GGGGGGVPAGPLQPAV
MSMEG_0076|M.smegmatis_MC2_155      GLPSDLPG-GPDIPGLDDPSLKPASAGGGGGGGVGGGGGGMPAAPLGPAV
MLBr_01556|M.leprae_Br4923          NLILKGDN-AGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLAS
MAB_3131c|M.abscessus_ATCC_199      NLILKGDN-AGTVEALEEALLGIAIDDEVQLRVIDRGVGGVTETNVNLAS
MAV_4827|M.avium_104                LSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGN
                                                                           *        . 

Rv3881c|M.tuberculosis_H37Rv        SAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMP-MGAAHQGQG-
Mb3911c|M.bovis_AF2122/97           SAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMP-MGAAHQGQG-
MMAR_5457|M.marinum_M               AALAGGESVRPAAAGDIAGAGQGGGAAGRGMAGGGMGMP-MGGAGQGQG-
MUL_2550|M.ulcerans_Agy99           DSISS-----QLGGRDLLGAG---AAPGAAMGSGGAGMAPMGAPGAGQAP
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          GAETVAPSPARPGAPI-PVASAGSGGGGGAMGGGVGGMAPMHG-AHGGGA
Mvan_0090|M.vanbaalenii_PYR-1       GAETVAPTPIVPAAAAGPGVSSGSGGVAGGMG--AGGMAPMMGGAHGGGA
MSMEG_0076|M.smegmatis_MC2_155      GADSVSPSPSSTRGGGVGVPGGPGGGAGGMMGGGMGGMGAGHGQGQGK--
MLBr_01556|M.leprae_Br4923          ASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLK
MAB_3131c|M.abscessus_ATCC_199      ASDAIIIGFNVRAEGKATELANREGVDIRYYSVIYQAIDEIESALKGMLK
MAV_4827|M.avium_104                YGGGHVPTPGAGGSGGSGGGHVPTPGAGGSGGSGGGHVPTPGTGGPGGTG
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        GAKSKGSQQE--DEALYTEDRA-------WTEAVIGNRRRQ---------
Mb3911c|M.bovis_AF2122/97           GAKSKGSQQE--DEALYTEDRA-------WTEAVIGNRRRQ---------
MMAR_5457|M.marinum_M               GAKSKGAQQD--EEALYTEDRE-------WTEAVIGNRRRQ---------
MUL_2550|M.ulcerans_Agy99           GQTGKGKRAEPGDELLYTEERP-------WTEGLIGKRPRKSAAEVAGPD
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          GEKKRNPQLSV-DEPLYVEDRP-------HTEPVIGVRPRRR--------
Mvan_0090|M.vanbaalenii_PYR-1       GEKKRNPALSP-DEPLYVEDRP-------HTEQVIGVRPRRR--------
MSMEG_0076|M.smegmatis_MC2_155      -EKKRDPKLAP-DEDLYTEDRA-------HTEGVIGHRARRE--------
MLBr_01556|M.leprae_Br4923          PIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVV
MAB_3131c|M.abscessus_ATCC_199      PVYEEVELGRAEIRAMFRSSKVGNIAGCLVTSGIIRRNAKARLLRDNIVV
MAV_4827|M.avium_104                GSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLPTPGAGTPGG
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        -----------------DSKESK---------------------------
Mb3911c|M.bovis_AF2122/97           -----------------DSKESK---------------------------
MMAR_5457|M.marinum_M               -----------------DNK------------------------------
MUL_2550|M.ulcerans_Agy99           VSAAPDSKAGPDSKAGSNSKDSK---------------------------
TH_2612|M.thermoresistible__bu      --------------------------------------------------
Mflv_0757|M.gilvum_PYR-GCK          ----------------GTPEDGKRGETS----------------------
Mvan_0090|M.vanbaalenii_PYR-1       ----------------GAAEDTKKGDT-----------------------
MSMEG_0076|M.smegmatis_MC2_155      ----------------KDSGKQQ---------------------------
MLBr_01556|M.leprae_Br4923          TDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQR
MAB_3131c|M.abscessus_ATCC_199      AETVTISSLRREKDDVVEVRDGYECGLTLTYNDIKEGDVIEAYELREKER
MAV_4827|M.avium_104                GLGGFGGGHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGH
                                                                                      

Rv3881c|M.tuberculosis_H37Rv        -
Mb3911c|M.bovis_AF2122/97           -
MMAR_5457|M.marinum_M               -
MUL_2550|M.ulcerans_Agy99           -
TH_2612|M.thermoresistible__bu      -
Mflv_0757|M.gilvum_PYR-GCK          -
Mvan_0090|M.vanbaalenii_PYR-1       -
MSMEG_0076|M.smegmatis_MC2_155      -
MLBr_01556|M.leprae_Br4923          A
MAB_3131c|M.abscessus_ATCC_199      V
MAV_4827|M.avium_104                K