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M. thermoresistible (build 8) TH_2758 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 710540 - 711340
length: 267

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2758 - - 100% (267) short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_1828 - 2e-37 35.42% (271) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8) TH_4323 - 1e-26 31.95% (266) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1277c - 3e-37 36.63% (273) short-chain type dehydrogenase/reductase
M. gilvum PYR-GCK Mflv_2216 - 2e-34 35.56% (270) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv1245c - 3e-37 36.63% (273) short-chain type dehydrogenase/reductase
M. leprae Br4923 MLBr_01094 - 8e-35 34.69% (271) short chain alcohol dehydrogenase
M. abscessus ATCC 19977 MAB_1388c - 1e-35 35.43% (254) short-chain dehydrogenase/reductase
M. marinum M MMAR_4195 - 3e-39 38.17% (262) short-chain type dehydrogenase/reductase
M. avium 104 MAV_1958 - 1e-60 48.50% (266) short chain dehydrogenase
M. smegmatis MC2 155 MSMEG_2872 - 1e-112 77.57% (263) short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99 MUL_4501 - 2e-38 37.40% (262) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1 Mvan_4479 - 1e-36 34.81% (270) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4195|M.marinum_M               MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MUL_4501|M.ulcerans_Agy99           MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
Mb1277c|M.bovis_AF2122/97           MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDGLADTEHRL
Rv1245c|M.tuberculosis_H37Rv        MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDGLADTEHRL
Mflv_2216|M.gilvum_PYR-GCK          MQGFAGKVAVVTGAGSGIGQALAIELGRSGALVAISDVDTEGLAVTEERL
Mvan_4479|M.vanbaalenii_PYR-1       MEGFAGKVAVVTGAGSGIGQALAIELGRSGARVAISDVDTEGLAVTEERL
MLBr_01094|M.leprae_Br4923          MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQL
MAB_1388c|M.abscessus_ATCC_199      MEGFSGKVAVVTGAGSGIGRALAVELARSGAKIAISDIDNEGLAETERQV
TH_2758|M.thermoresistible__bu      -VRITDRVFVVTGSGNGMGREVAVELGRRGAHVAAVDIDREGLAGTAELV
MSMEG_2872|M.smegmatis_MC2_155      -MRIADRVFVVTGAGNGMGREVALGLARRGAHVAAVDLDEAGLAGTAERA
MAV_1958|M.avium_104                -MKIRDKVFVVTGGANGMGRQVALLLVAKGARVAVVDVDVAGLKETAALT
                                       : .:* ****...*:*: :*: *   ** :*  *:*  **  *    

MMAR_4195|M.marinum_M               TALGAEVKTDRLDVTEREAFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MUL_4501|M.ulcerans_Agy99           TALGAEVKTDRLDVTERETFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
Mb1277c|M.bovis_AF2122/97           KAISTPVKTDRLDVTEREAFLAYADAVNEHFGTVNQIYNNAGIAFTGDIE
Rv1245c|M.tuberculosis_H37Rv        KAISTPVKTDRLDVTEREAFLAYADAVNEHFGTVNQIYNNAGIAFTGDIE
Mflv_2216|M.gilvum_PYR-GCK          KAIGTHVKSDRLNVTERERFLQYADDVAEHFGKVHQIYNNAGIAFTGDIE
Mvan_4479|M.vanbaalenii_PYR-1       KAIGAQVKSDRLDVTERETFLLYADDVAEHFGSVNQIYNNAGIAFTGDIE
MLBr_01094|M.leprae_Br4923          KAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTGDVE
MAB_1388c|M.abscessus_ATCC_199      KALGAEVRADRLNVAEREAFLLYADAIKDHFGKVNQIYNNAGIAYQGEVE
TH_2758|M.thermoresistible__bu      RATGARITTHVVDVTDDNAVAALPAAVLDAHGQVDGLVNIAGIAQRFALF
MSMEG_2872|M.smegmatis_MC2_155      RGTGARMSTHVLNVTDRDAVAGLPDAVLDVHGQIDGLVNIAGIAQRFALF
MAV_1958|M.avium_104                APQAGRISTHVVDVAERSATSALPDAVVAAHGAVDGLVNVAGIIHRFARL
                                       .    :. ::*:: .     .  :   .* :. : * ***       

MMAR_4195|M.marinum_M               -VCAFKDIDRVMDVDFGGVLNGTKAFLPYLIASGDGHVINVSSVFGLFSV
MUL_4501|M.ulcerans_Agy99           -VCAFKDIDRVMDVDFGGVLNGTKTFLPYLIASGDGHVINVSSVFGLFSV
Mb1277c|M.bovis_AF2122/97           -VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISSVFGLFSA
Rv1245c|M.tuberculosis_H37Rv        -VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISSVFGLFSA
Mflv_2216|M.gilvum_PYR-GCK          -VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSV
Mvan_4479|M.vanbaalenii_PYR-1       -ITQFKDIERVMDVDYWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSV
MLBr_01094|M.leprae_Br4923          -VSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFSV
MAB_1388c|M.abscessus_ATCC_199      -ESQFKDIERIIDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSLFGVLSM
TH_2758|M.thermoresistible__bu      SDLGAEALDRVPVVNFTGTVRMCRAFLPILLARPEANITNMSSLSALVPF
MSMEG_2872|M.smegmatis_MC2_155      TDLEADQIDRVTTVNFLGTVQMCRAFLPVLRQRPEANITNMSSLSALVPF
MAV_1958|M.avium_104                NDLEFGEIERVLNINLYGVLNVTKAFLPHLLKRPTAHITIVSSMASYAPV
                                           ::*:  ::  *.:.  ::*** *     .::  :**: .  . 

MMAR_4195|M.marinum_M               SGQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNAT
MUL_4501|M.ulcerans_Agy99           SGQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNAT
Mb1277c|M.bovis_AF2122/97           PGQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVKTAIARNAT
Rv1245c|M.tuberculosis_H37Rv        PGQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVKTAIARNAT
Mflv_2216|M.gilvum_PYR-GCK          PGQGAYNAAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIARNAG
Mvan_4479|M.vanbaalenii_PYR-1       PGQAAYNSAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIARNAS
MLBr_01094|M.leprae_Br4923          PGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARNAT
MAB_1388c|M.abscessus_ATCC_199      PGQSAYNSAKFAVRGFTESLRQEMIIGKKPVAVTCVHPGGIKTAIARNST
TH_2758|M.thermoresistible__bu      ASQLLYSASKAAVKQFSEGLDAELVGTD--VRVVTVFPGNVATELAKNS-
MSMEG_2872|M.smegmatis_MC2_155      ASQVLYSASKAAVQQFSEGLDAELADTN--VRVVTVFPGQVSTNLAQNS-
MAV_1958|M.avium_104                PGQAIYGASKAAVKMLAEGLNSELRDTN--VRVSVVFPGAVKTDIAVNS-
                                    ..*  *.::* **: ::*.*  *:      * *  *.** : * :* *: 

MMAR_4195|M.marinum_M               AAEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPDAKAL
MUL_4501|M.ulcerans_Agy99           AAEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPDAKAL
Mb1277c|M.bovis_AF2122/97           AAEGLDQAELAETFDKRVAHLSPQRAAQIILTGVAKNKARVLVGVDAKVL
Rv1245c|M.tuberculosis_H37Rv        AAEGLDQAELAETFDKRVAHLSPQRAAQIILTGVAKNKARVLVGVDAKVL
Mflv_2216|M.gilvum_PYR-GCK          AAEGLDAEELAKTFDKKLASTTPEKAAQVILDGVRKNKARILIGNDAKMF
Mvan_4479|M.vanbaalenii_PYR-1       AAEGLDAEELAKAFDKKLASTTPEKAAKIILDGVRKNRARILVGNDAKVF
MLBr_01094|M.leprae_Br4923          AAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVGPDAKVA
MAB_1388c|M.abscessus_ATCC_199      TAEGYDQQAMAAMFDKYLANTSPEAAARIILTAVRKKKPRVLVGPDAKIL
TH_2758|M.thermoresistible__bu      ---GVEMLD---AGSRRVYATSPEAAGRKIVAGIARDRYRVIIGADAHVL
MSMEG_2872|M.smegmatis_MC2_155      ---GVKMLD---AGGRRAPVTTPEAAGRKIVTGIAKDRYRVIIGTDAHVL
MAV_1958|M.avium_104                ---GAMTPDENEATARSMRMLPSTVAAAKIVRGIEKDSRRVFVGLDALLL
                                       *                 ..  *.  *: .: :.  *:::* **   

MMAR_4195|M.marinum_M               DIVVRLTG-SGYQRLFMPVLGRLVPASHR--
MUL_4501|M.ulcerans_Agy99           DIVVRLTG-SGYQRLFMPVLGRLVPASHR--
Mb1277c|M.bovis_AF2122/97           DLVVRLTG-SGYQRIFPIITGRLIPRPR---
Rv1245c|M.tuberculosis_H37Rv        DLVVRLTG-SGYQRIFPIITGRLIPRPR---
Mflv_2216|M.gilvum_PYR-GCK          EIAIRALG-AGYQSVFPKVVARLTPPAK---
Mvan_4479|M.vanbaalenii_PYR-1       DVVVRVLG-AGYQSLFPKAVARLTPPAK---
MLBr_01094|M.leprae_Br4923          NVVVRFSGGAGYQRLFAQVASRLILNQR---
MAB_1388c|M.abscessus_ATCC_199      DVIVRLTG-ARYQDIFSVVTRFILPRPGKK-
TH_2758|M.thermoresistible__bu      HALARIAPRRTARLVARQITSVLREQ-----
MSMEG_2872|M.smegmatis_MC2_155      YTLSRLAPRRTARMVAKQIKSVL--------
MAV_1958|M.avium_104                DKLNRLTPASAAKLIWSQMRDVLPPAGQSLR
                                        *       : :       :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2758	-	-	100% (267)	short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_1828	-	2e-37	35.42% (271)	PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8)	TH_4323	-	1e-26	31.95% (266)	PUTATIVE short-chain dehydrogenase/reductase SDR