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M. thermoresistible (build 8) TH_2632 (dapB)

annotation: dihydrodipicolinate reductase, N-terminus domain protein
coordinates: 4621833 - 4622912
length: 360

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2632dapB-100% (360)dihydrodipicolinate reductase, N-terminus domain protein
M. thermoresistible (build 8)TH_4249-3e-6635.90% (351) PUTATIVE dihydrodipicolinate reductase
M. thermoresistible (build 8)TH_3380-2e-3729.59% (365) PUTATIVE dihydrodipicolinate reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0949c-8e-2927.52% (367) hypothetical protein Mb0949c
M. gilvum PYR-GCKMflv_2754-0.086.48% (355) dihydrodipicolinate reductase
M. tuberculosis H37RvRv0926c-8e-2927.52% (367) hypothetical protein Rv0926c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0727-1e-17377.62% (353) putative dihydrodipicolinate reductase
M. marinum MMMAR_1936-0.085.31% (354) hypothetical protein MMAR_1936
M. avium 104MAV_3665dapB0.087.08% (356) dihydrodipicolinate reductase N-terminus domain-containing
M. smegmatis MC2 155MSMEG_0733dapB0.091.92% (359) dihydrodipicolinate reductase N-terminus domain-containing
M. ulcerans Agy99MUL_2162-0.086.14% (339) hypothetical protein MUL_2162
M. vanbaalenii PYR-1Mvan_3783-0.086.48% (355) dihydrodipicolinate reductase

CLUSTAL 2.0.9 multiple sequence alignment


TH_2632|M.thermoresistible__bu      ---MSAPIRIFQVATGNVGTEMIRRLQHRPDLELIGVHCYTPEKVGRDVG
MSMEG_0733|M.smegmatis_MC2_155      ---MSAPIRVFQVATGNVGTEMIKRLQHRTDLELVGLHCYTPEKVGRDAG
Mflv_2754|M.gilvum_PYR-GCK          -----MTVKVFQVATGNVGTEMIKRIADQPDLELIGVHCYSPEKVGRDVG
Mvan_3783|M.vanbaalenii_PYR-1       -----MTIKVFQVATGNVGSEMIKRIADQPDLELIGVHCYSPDKVGRDAG
MAV_3665|M.avium_104                --MGTAPIRVFQVGSGNVGSEMIRRIATQPDLELIGVHCYSPEKIGKDTG
MMAR_1936|M.marinum_M               MSARPQPIRVFQVATGNVGREMIKRLQTRPDLELIGLHCYSPDKVGADAG
MUL_2162|M.ulcerans_Agy99           ---------------------MIKRLQTRPDLELIGLHCYSPDKVGADAG
MAB_0727|M.abscessus_ATCC_1997      ----MSVIRVFQVATGNVGTEMIRRIASHPDLELAGLHCYSPEKVGRDAG
Mb0949c|M.bovis_AF2122/97           -----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAA
Rv0926c|M.tuberculosis_H37Rv        -----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAA
                                                          :: :   .::** *:   :  * * *..

TH_2632|M.thermoresistible__bu      EIAGIGP-IGVKATGTIDEIIAAEPDVLTFHGVFPD-----EDLYVKVLE
MSMEG_0733|M.smegmatis_MC2_155      EIAGIGP-VGVTATGTIDEIIAARPDVLTFHGVFPD-----EDLYIRVLE
Mflv_2754|M.gilvum_PYR-GCK          ELAGLAP-NGVKATGTVDEIIAARPDVVTFHGVFPD-----EDLYVRVLE
Mvan_3783|M.vanbaalenii_PYR-1       EIAGLAP-NGVIATGSVEEIIAAKPDVLTFHGVFPD-----EDLYVKVLE
MAV_3665|M.avium_104                QFAGLAP-NGVKFTGTVEEIIAAKPDVLTFHGVFPD-----EDLYVKVLE
MMAR_1936|M.marinum_M               ELAGIGP-IGVTATGSVSDIVAAKPDVLTFHGVFPD-----EDLYVKVLE
MUL_2162|M.ulcerans_Agy99           ELAGIGP-IGVTATGSVSDIVAARPDVLTFHGVFPD-----EDLYVKVLE
MAB_0727|M.abscessus_ATCC_1997      ELVGLEP-NGVIATGTVEEIVAAKPDVLTFHGVFPD-----EDLYVKVLE
Mb0949c|M.bovis_AF2122/97           ELAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILA
Rv0926c|M.tuberculosis_H37Rv        ELAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILA
                                    ::.*:    **  :  :. ::*: *   .::.:  :      : * ::* 

TH_2632|M.thermoresistible__bu      AGIDIVTTADWITGWHRDTNHPHPSGKPVTELLAEACEKGGSTFYGTGMN
MSMEG_0733|M.smegmatis_MC2_155      AGINIVTTADWITGWHRDTNHPHPSGRPVSELLAEACRKGSSTFYGTGMN
Mflv_2754|M.gilvum_PYR-GCK          AGINIVTTADWITGWHRDRNHPHHSGKPVTQLLQEACEKGGSTFYGTGMN
Mvan_3783|M.vanbaalenii_PYR-1       AGINIVTTADWITGWHRDRNHPHPSGKPVTQLLQEACEKGGSTFYGTGMN
MAV_3665|M.avium_104                AGIDIVTTADWITGWHRDKNHPHPSGKPVTQLLAEAAAKGGATFYGTGMN
MMAR_1936|M.marinum_M               AGINIVTTADWITGWHRDHNHPHPSGKPVTQLLAEACEKGGATFYGTGMN
MUL_2162|M.ulcerans_Agy99           AGINIVTTADWITGWHRDHNHPHPSGKPVTQLLAEACEKGGATFYGTGMN
MAB_0727|M.abscessus_ATCC_1997      AGIDIVTTADWITGHHRDQNHPHPSGRPTTEVLQQACERGGSTFYGTGMN
Mb0949c|M.bovis_AF2122/97           AGINIVGSGPVFLQYPWQVIP-----DEIIKPLQDAARAGNSSLYVNGID
Rv0926c|M.tuberculosis_H37Rv        AGINIVGSGPVFLQYPWQVIP-----DEIIKPLQDAARAGNSSLYVNGID
                                    ***:** :.  :     :            : * :*.  *.:::* .*::

TH_2632|M.thermoresistible__bu      PGLN-QILGVVCSADVSEIENVTTIESVDVSCHHSKDTWVEVG-YGLPVD
MSMEG_0733|M.smegmatis_MC2_155      PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVG-YGLPVD
Mflv_2754|M.gilvum_PYR-GCK          PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVG-YGQPVD
Mvan_3783|M.vanbaalenii_PYR-1       PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVG-YGQPVD
MAV_3665|M.avium_104                PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVG-YGQPVD
MMAR_1936|M.marinum_M               PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKETWIEVG-YGQPVD
MUL_2162|M.ulcerans_Agy99           PGLN-QILGVVCSADVSEIENVTTIESVDVSCHHSKETWIEVG-YGQPVD
MAB_0727|M.abscessus_ATCC_1997      PGLT-QILGVIHSCDVAEIENVTVIESVDVSCHHSVDSWEMVG-YGLPVG
Mb0949c|M.bovis_AF2122/97           PGFANDLLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMD
Rv0926c|M.tuberculosis_H37Rv        PGFANDLLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMD
                                    **:  ::* :  :    .**::  :* ** : :.*      *  :* *:.

TH_2632|M.thermoresistible__bu      DPEIPAKLEKYTRVFSDSVLMMADCFGLTLDEVTFSAELGACTRDVDLGW
MSMEG_0733|M.smegmatis_MC2_155      DPSIPGKLEKYTRVFADSVLLMADCFGLQLDEVKFSAELGACTKDVDLGW
Mflv_2754|M.gilvum_PYR-GCK          DPEIPGKLEKYTRVFADSVYMMADCFDLTLDEVKFSYELGACTKDVDLGW
Mvan_3783|M.vanbaalenii_PYR-1       DPEIPGKLEKYTRVFADSVYMMADCFDLTLDEVKFSYELGACTKDVDLGW
MAV_3665|M.avium_104                DPEIPAKLEKYTRVFADSVYMMADCFDLTLDEVTFSYELGACTKDVDLGW
MMAR_1936|M.marinum_M               DPDIPAKLEKYTRVFADSVLMMADCFDLPLDEVKFSYELGACTKDVDLGW
MUL_2162|M.ulcerans_Agy99           DPDIPAKLEKYTRVFADSVLMMADCFDLPLDEVKFSYELGACTKDVDLGW
MAB_0727|M.abscessus_ATCC_1997      DPSIPALLEKGTRVFADGVYLMADCFGLELDDVTFSYELGACTEDIDLGW
Mb0949c|M.bovis_AF2122/97           QIPMLLQPGVLSLAWGSVVRQLAAGLGISLDGVEEMYVREPAPEAFNIAS
Rv0926c|M.tuberculosis_H37Rv        QIPMLLQPGVLSLAWGSVVRQLAAGLGISLDGVEEMYVREPAPEAFNIAS
                                    :  :       : .:.. *  :*  :.: ** *       .... .::. 

TH_2632|M.thermoresistible__bu      YQLPKGSLGGSYIKYQGMVDGVPRIETHLEWQMTPHTDPHWDIKG----C
MSMEG_0733|M.smegmatis_MC2_155      YQLPKGSLGGNYIKYQGMVDGVPRIETHLEWQMTPHTDPHWDIKG----C
Mflv_2754|M.gilvum_PYR-GCK          YQLPKGSLGGNYIRYQGMVDGVPRVETHLEWQMTPHTDPSWDIKG----C
Mvan_3783|M.vanbaalenii_PYR-1       YRLPKGSLGGNYIKYQGMVDGVPRVETHLEWQMTPHTDPSWDIKG----C
MAV_3665|M.avium_104                YTLPKGSLGGNYIKYQGMVDGVPRVETHLEWQMTPHTDPSWNVKG----C
MMAR_1936|M.marinum_M               YTLPKGSLGGNYLKYQGMVGGVPRVETHLEWQMTPHTDPSWNIKG----C
MUL_2162|M.ulcerans_Agy99           YTLPKGSLGGNYLKYQGMVGGVPRVETHLEWQMTPHTDPSWNIKG----C
MAB_0727|M.abscessus_ATCC_1997      YRLPKGSLGANYLKYQGIVGGVPKVEVHVEWQMTPKTEPHWNVKG----C
Mb0949c|M.bovis_AF2122/97           GHIPKGSAAALRFEVLGLVDGVPAVVLEHVTRLRADLCPEWPQPAQPGGS
Rv0926c|M.tuberculosis_H37Rv        GHIPKGSAAALRFEVLGLVDGVPAVVLEHVTRLRADLCPEWPQPAQPGGS
                                      :**** ..  :.  *:*.*** :  .   :: ..  * *   .    .

TH_2632|M.thermoresistible__bu      YITQIKGDPCVYNKHMIFPKPGVDLSDPDSFASIGMTVTGLPALNAIRSV
MSMEG_0733|M.smegmatis_MC2_155      YITQIKGDPCVYNKHMIFPKPGVDLSDPDSFASIGMTVTGMPALNAIASV
Mflv_2754|M.gilvum_PYR-GCK          YITQIKGDPNIYNKHMIFPKPGVDLSDPASFASIGMTVTGMPALASITSV
Mvan_3783|M.vanbaalenii_PYR-1       YITQIKGDPNIYNKHMIFPKPGVDLSDPANFASIGMTVTGMPALHAIKSV
MAV_3665|M.avium_104                YITQIKGDPCVYNKHMIFPKPGVDLSNPDNFASIGMTVTGMPALAAIRSV
MMAR_1936|M.marinum_M               YITQIKGDPCIYNKHMIFPKAGVDLSNPENFASIGMTVTGMPALNSIKSV
MUL_2162|M.ulcerans_Agy99           YITQIKGDPCIYNKHMIFPKAGVDLSNPDNFASIGMTVTGMPALNSIKSV
MAB_0727|M.abscessus_ATCC_1997      YITKIQGDPCVYSKHMVIPKPGTDFTDPAAFASVGMTVTGLPALNAIRSV
Mb0949c|M.bovis_AF2122/97           YRIEISGEPCYAMDICLSSRHGDHN-------HAGLVATAMRIVNAIPAV
Rv0926c|M.tuberculosis_H37Rv        YRIEISGEPCYAMDICLSSRHGDHN-------HAGLVATAMRIVNAIPAV
                                    *  :*.*:*    .  : .: * .          *:..*.:  : :* :*

TH_2632|M.thermoresistible__bu      VAAPPGLLTSADVPLRGFAGRFTL-
MSMEG_0733|M.smegmatis_MC2_155      VAAPPGLLTSADVPLRGFAGRFKL-
Mflv_2754|M.gilvum_PYR-GCK          VAARPGIITSADLPLRGFAGRFKL-
Mvan_3783|M.vanbaalenii_PYR-1       VAARPGLMTSADLPLRGFAGRFKL-
MAV_3665|M.avium_104                VAAPPGLLTSADLPLRGFAGRFKK-
MMAR_1936|M.marinum_M               VAARSGLITSAELPLRGFAGRFKN-
MUL_2162|M.ulcerans_Agy99           VAARPGLITSAELPLRGFAGRFKN-
MAB_0727|M.abscessus_ATCC_1997      IDAPPGILTSADLPLRGFAGRFK--
Mb0949c|M.bovis_AF2122/97           VAAEPGIRTTLDLPLITGEGRYAAA
Rv0926c|M.tuberculosis_H37Rv        VAAEPGIRTTLDLPLITGEGRYAAA
                                    : * .*: *: ::**    **: