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MTVKVFQVATGNVGTEMIKRIADQPDLELIGVHCYSPEKVGRDVGELAGLAPNGVKATGTVDEIIAARPD VVTFHGVFPDEDLYVRVLEAGINIVTTADWITGWHRDRNHPHHSGKPVTQLLQEACEKGGSTFYGTGMNP GLNQILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVGYGQPVDDPEIPGKLEKYTRVFADSVYMMA DCFDLTLDEVKFSYELGACTKDVDLGWYQLPKGSLGGNYIRYQGMVDGVPRVETHLEWQMTPHTDPSWDI KGCYITQIKGDPNIYNKHMIFPKPGVDLSDPASFASIGMTVTGMPALASITSVVAARPGIITSADLPLRG FAGRFKL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2754 | - | - | 100% (357) | dihydrodipicolinate reductase |
| M. gilvum PYR-GCK | Mflv_2658 | - | 4e-60 | 35.84% (346) | dihydrodipicolinate reductase |
| M. gilvum PYR-GCK | Mflv_1767 | - | 3e-58 | 34.96% (349) | dihydrodipicolinate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0949c | - | 2e-31 | 29.54% (369) | hypothetical protein Mb0949c |
| M. tuberculosis H37Rv | Rv0926c | - | 2e-31 | 29.54% (369) | hypothetical protein Rv0926c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0727 | - | 1e-169 | 76.55% (354) | putative dihydrodipicolinate reductase |
| M. marinum M | MMAR_1936 | - | 0.0 | 87.01% (354) | hypothetical protein MMAR_1936 |
| M. avium 104 | MAV_3665 | dapB | 0.0 | 88.70% (354) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. smegmatis MC2 155 | MSMEG_0733 | dapB | 0.0 | 86.76% (355) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. thermoresistible (build 8) | TH_2632 | - | 0.0 | 86.48% (355) | PUTATIVE dihydrodipicolinate reductase, N-terminus domain |
| M. ulcerans Agy99 | MUL_2162 | - | 0.0 | 87.65% (340) | hypothetical protein MUL_2162 |
| M. vanbaalenii PYR-1 | Mvan_3783 | - | 0.0 | 94.40% (357) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2754|M.gilvum_PYR-GCK -----MTVKVFQVATGNVGTEMIKRIADQPDLELIGVHCYSPEKVGRDVG
Mvan_3783|M.vanbaalenii_PYR-1 -----MTIKVFQVATGNVGSEMIKRIADQPDLELIGVHCYSPDKVGRDAG
MAV_3665|M.avium_104 --MGTAPIRVFQVGSGNVGSEMIRRIATQPDLELIGVHCYSPEKIGKDTG
MMAR_1936|M.marinum_M MSARPQPIRVFQVATGNVGREMIKRLQTRPDLELIGLHCYSPDKVGADAG
MUL_2162|M.ulcerans_Agy99 ---------------------MIKRLQTRPDLELIGLHCYSPDKVGADAG
MSMEG_0733|M.smegmatis_MC2_155 ---MSAPIRVFQVATGNVGTEMIKRLQHRTDLELVGLHCYTPEKVGRDAG
TH_2632|M.thermoresistible__bu ---MSAPIRIFQVATGNVGTEMIRRLQHRPDLELIGVHCYTPEKVGRDVG
MAB_0727|M.abscessus_ATCC_1997 ----MSVIRVFQVATGNVGTEMIRRIASHPDLELAGLHCYSPEKVGRDAG
Mb0949c|M.bovis_AF2122/97 -----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAA
Rv0926c|M.tuberculosis_H37Rv -----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAA
:: : .::** *: : * * *..
Mflv_2754|M.gilvum_PYR-GCK ELAGLAP-NGVKATGTVDEIIAARPDVVTFHGVFPD-----EDLYVRVLE
Mvan_3783|M.vanbaalenii_PYR-1 EIAGLAP-NGVIATGSVEEIIAAKPDVLTFHGVFPD-----EDLYVKVLE
MAV_3665|M.avium_104 QFAGLAP-NGVKFTGTVEEIIAAKPDVLTFHGVFPD-----EDLYVKVLE
MMAR_1936|M.marinum_M ELAGIGP-IGVTATGSVSDIVAAKPDVLTFHGVFPD-----EDLYVKVLE
MUL_2162|M.ulcerans_Agy99 ELAGIGP-IGVTATGSVSDIVAARPDVLTFHGVFPD-----EDLYVKVLE
MSMEG_0733|M.smegmatis_MC2_155 EIAGIGP-VGVTATGTIDEIIAARPDVLTFHGVFPD-----EDLYIRVLE
TH_2632|M.thermoresistible__bu EIAGIGP-IGVKATGTIDEIIAAEPDVLTFHGVFPD-----EDLYVKVLE
MAB_0727|M.abscessus_ATCC_1997 ELVGLEP-NGVIATGTVEEIVAAKPDVLTFHGVFPD-----EDLYVKVLE
Mb0949c|M.bovis_AF2122/97 ELAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILA
Rv0926c|M.tuberculosis_H37Rv ELAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILA
::.*: ** : :. ::*: * .::.: : : * ::*
Mflv_2754|M.gilvum_PYR-GCK AGINIVTTADWITGWHRDRNHPHHSGKPVTQLLQEACEKGGSTFYGTGMN
Mvan_3783|M.vanbaalenii_PYR-1 AGINIVTTADWITGWHRDRNHPHPSGKPVTQLLQEACEKGGSTFYGTGMN
MAV_3665|M.avium_104 AGIDIVTTADWITGWHRDKNHPHPSGKPVTQLLAEAAAKGGATFYGTGMN
MMAR_1936|M.marinum_M AGINIVTTADWITGWHRDHNHPHPSGKPVTQLLAEACEKGGATFYGTGMN
MUL_2162|M.ulcerans_Agy99 AGINIVTTADWITGWHRDHNHPHPSGKPVTQLLAEACEKGGATFYGTGMN
MSMEG_0733|M.smegmatis_MC2_155 AGINIVTTADWITGWHRDTNHPHPSGRPVSELLAEACRKGSSTFYGTGMN
TH_2632|M.thermoresistible__bu AGIDIVTTADWITGWHRDTNHPHPSGKPVTELLAEACEKGGSTFYGTGMN
MAB_0727|M.abscessus_ATCC_1997 AGIDIVTTADWITGHHRDQNHPHPSGRPTTEVLQQACERGGSTFYGTGMN
Mb0949c|M.bovis_AF2122/97 AGINIVGSGPVFLQYPWQVIP-----DEIIKPLQDAARAGNSSLYVNGID
Rv0926c|M.tuberculosis_H37Rv AGINIVGSGPVFLQYPWQVIP-----DEIIKPLQDAARAGNSSLYVNGID
***:** :. : : : * :*. *.:::* .*::
Mflv_2754|M.gilvum_PYR-GCK PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVG-YGQPVD
Mvan_3783|M.vanbaalenii_PYR-1 PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVG-YGQPVD
MAV_3665|M.avium_104 PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVG-YGQPVD
MMAR_1936|M.marinum_M PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKETWIEVG-YGQPVD
MUL_2162|M.ulcerans_Agy99 PGLN-QILGVVCSADVSEIENVTTIESVDVSCHHSKETWIEVG-YGQPVD
MSMEG_0733|M.smegmatis_MC2_155 PGLN-QILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVG-YGLPVD
TH_2632|M.thermoresistible__bu PGLN-QILGVVCSADVSEIENVTTIESVDVSCHHSKDTWVEVG-YGLPVD
MAB_0727|M.abscessus_ATCC_1997 PGLT-QILGVIHSCDVAEIENVTVIESVDVSCHHSVDSWEMVG-YGLPVG
Mb0949c|M.bovis_AF2122/97 PGFANDLLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMD
Rv0926c|M.tuberculosis_H37Rv PGFANDLLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMD
**: ::* : : .**:: :* ** : :.* * :* *:.
Mflv_2754|M.gilvum_PYR-GCK DPEIPGKLEKYTRVFADSVYMMADCFDLTLDEVKFSYELGACTKDVDLGW
Mvan_3783|M.vanbaalenii_PYR-1 DPEIPGKLEKYTRVFADSVYMMADCFDLTLDEVKFSYELGACTKDVDLGW
MAV_3665|M.avium_104 DPEIPAKLEKYTRVFADSVYMMADCFDLTLDEVTFSYELGACTKDVDLGW
MMAR_1936|M.marinum_M DPDIPAKLEKYTRVFADSVLMMADCFDLPLDEVKFSYELGACTKDVDLGW
MUL_2162|M.ulcerans_Agy99 DPDIPAKLEKYTRVFADSVLMMADCFDLPLDEVKFSYELGACTKDVDLGW
MSMEG_0733|M.smegmatis_MC2_155 DPSIPGKLEKYTRVFADSVLLMADCFGLQLDEVKFSAELGACTKDVDLGW
TH_2632|M.thermoresistible__bu DPEIPAKLEKYTRVFSDSVLMMADCFGLTLDEVTFSAELGACTRDVDLGW
MAB_0727|M.abscessus_ATCC_1997 DPSIPALLEKGTRVFADGVYLMADCFGLELDDVTFSYELGACTEDIDLGW
Mb0949c|M.bovis_AF2122/97 QIPMLLQPGVLSLAWGSVVRQLAAGLGISLDGVEEMYVREPAPEAFNIAS
Rv0926c|M.tuberculosis_H37Rv QIPMLLQPGVLSLAWGSVVRQLAAGLGISLDGVEEMYVREPAPEAFNIAS
: : : .:.. * :* :.: ** * .... .::.
Mflv_2754|M.gilvum_PYR-GCK YQLPKGSLGGNYIRYQGMVDGVPRVETHLEWQMTPHTDPSWDIKG----C
Mvan_3783|M.vanbaalenii_PYR-1 YRLPKGSLGGNYIKYQGMVDGVPRVETHLEWQMTPHTDPSWDIKG----C
MAV_3665|M.avium_104 YTLPKGSLGGNYIKYQGMVDGVPRVETHLEWQMTPHTDPSWNVKG----C
MMAR_1936|M.marinum_M YTLPKGSLGGNYLKYQGMVGGVPRVETHLEWQMTPHTDPSWNIKG----C
MUL_2162|M.ulcerans_Agy99 YTLPKGSLGGNYLKYQGMVGGVPRVETHLEWQMTPHTDPSWNIKG----C
MSMEG_0733|M.smegmatis_MC2_155 YQLPKGSLGGNYIKYQGMVDGVPRIETHLEWQMTPHTDPHWDIKG----C
TH_2632|M.thermoresistible__bu YQLPKGSLGGSYIKYQGMVDGVPRIETHLEWQMTPHTDPHWDIKG----C
MAB_0727|M.abscessus_ATCC_1997 YRLPKGSLGANYLKYQGIVGGVPKVEVHVEWQMTPKTEPHWNVKG----C
Mb0949c|M.bovis_AF2122/97 GHIPKGSAAALRFEVLGLVDGVPAVVLEHVTRLRADLCPEWPQPAQPGGS
Rv0926c|M.tuberculosis_H37Rv GHIPKGSAAALRFEVLGLVDGVPAVVLEHVTRLRADLCPEWPQPAQPGGS
:**** .. :. *:*.*** : . :: .. * * . .
Mflv_2754|M.gilvum_PYR-GCK YITQIKGDPNIYNKHMIFPKPGVDLSDPASFASIGMTVTGMPALASITSV
Mvan_3783|M.vanbaalenii_PYR-1 YITQIKGDPNIYNKHMIFPKPGVDLSDPANFASIGMTVTGMPALHAIKSV
MAV_3665|M.avium_104 YITQIKGDPCVYNKHMIFPKPGVDLSNPDNFASIGMTVTGMPALAAIRSV
MMAR_1936|M.marinum_M YITQIKGDPCIYNKHMIFPKAGVDLSNPENFASIGMTVTGMPALNSIKSV
MUL_2162|M.ulcerans_Agy99 YITQIKGDPCIYNKHMIFPKAGVDLSNPDNFASIGMTVTGMPALNSIKSV
MSMEG_0733|M.smegmatis_MC2_155 YITQIKGDPCVYNKHMIFPKPGVDLSDPDSFASIGMTVTGMPALNAIASV
TH_2632|M.thermoresistible__bu YITQIKGDPCVYNKHMIFPKPGVDLSDPDSFASIGMTVTGLPALNAIRSV
MAB_0727|M.abscessus_ATCC_1997 YITKIQGDPCVYSKHMVIPKPGTDFTDPAAFASVGMTVTGLPALNAIRSV
Mb0949c|M.bovis_AF2122/97 YRIEISGEPCYAMDICLSSRHGDHN-------HAGLVATAMRIVNAIPAV
Rv0926c|M.tuberculosis_H37Rv YRIEISGEPCYAMDICLSSRHGDHN-------HAGLVATAMRIVNAIPAV
* :*.*:* . : .: * . *:..*.: : :* :*
Mflv_2754|M.gilvum_PYR-GCK VAARPGIITSADLPLRGFAGRFKL-
Mvan_3783|M.vanbaalenii_PYR-1 VAARPGLMTSADLPLRGFAGRFKL-
MAV_3665|M.avium_104 VAAPPGLLTSADLPLRGFAGRFKK-
MMAR_1936|M.marinum_M VAARSGLITSAELPLRGFAGRFKN-
MUL_2162|M.ulcerans_Agy99 VAARPGLITSAELPLRGFAGRFKN-
MSMEG_0733|M.smegmatis_MC2_155 VAAPPGLLTSADVPLRGFAGRFKL-
TH_2632|M.thermoresistible__bu VAAPPGLLTSADVPLRGFAGRFTL-
MAB_0727|M.abscessus_ATCC_1997 IDAPPGILTSADLPLRGFAGRFK--
Mb0949c|M.bovis_AF2122/97 VAAEPGIRTTLDLPLITGEGRYAAA
Rv0926c|M.tuberculosis_H37Rv VAAEPGIRTTLDLPLITGEGRYAAA
: * .*: *: ::** **: