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SAPIRVFQVATGNVGTEMIKRLQHRTDLELVGLHCYTPEKVGRDAGEIAGIGPVGVTATGTIDEIIAARP DVLTFHGVFPDEDLYIRVLEAGINIVTTADWITGWHRDTNHPHPSGRPVSELLAEACRKGSSTFYGTGMN PGLNQILGVVCSADVAEIENVTTIESVDVSCHHSKDTWIEVGYGLPVDDPSIPGKLEKYTRVFADSVLLM ADCFGLQLDEVKFSAELGACTKDVDLGWYQLPKGSLGGNYIKYQGMVDGVPRIETHLEWQMTPHTDPHWD IKGCYITQIKGDPCVYNKHMIFPKPGVDLSDPDSFASIGMTVTGMPALNAIASVVAAPPGLLTSADVPLR GFAGRFKL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0733 | dapB | - | 100% (359) | dihydrodipicolinate reductase N-terminus domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0560 | dapB | 3e-66 | 36.71% (346) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. smegmatis MC2 155 | MSMEG_5586 | - | 1e-29 | 27.35% (362) | hypothetical protein MSMEG_5586 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1088 | - | 3e-29 | 27.53% (356) | hypothetical protein Mb1088 |
| M. gilvum PYR-GCK | Mflv_2754 | - | 0.0 | 86.76% (355) | dihydrodipicolinate reductase |
| M. tuberculosis H37Rv | Rv1059 | - | 3e-29 | 27.53% (356) | hypothetical protein Rv1059 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0727 | - | 1e-171 | 76.84% (354) | putative dihydrodipicolinate reductase |
| M. marinum M | MMAR_1936 | - | 0.0 | 85.92% (355) | hypothetical protein MMAR_1936 |
| M. avium 104 | MAV_3665 | dapB | 0.0 | 84.31% (357) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. thermoresistible (build 8) | TH_2632 | - | 0.0 | 91.92% (359) | PUTATIVE dihydrodipicolinate reductase, N-terminus domain |
| M. ulcerans Agy99 | MUL_2162 | - | 0.0 | 86.18% (340) | hypothetical protein MUL_2162 |
| M. vanbaalenii PYR-1 | Mvan_3783 | - | 0.0 | 86.76% (355) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0733|M.smegmatis_MC2_155 ---MSAPIRVFQVATGNVGTEMIKRLQHRTDLELVGLHCYTPEKVGRDAG
TH_2632|M.thermoresistible__bu ---MSAPIRIFQVATGNVGTEMIRRLQHRPDLELIGVHCYTPEKVGRDVG
Mflv_2754|M.gilvum_PYR-GCK -----MTVKVFQVATGNVGTEMIKRIADQPDLELIGVHCYSPEKVGRDVG
Mvan_3783|M.vanbaalenii_PYR-1 -----MTIKVFQVATGNVGSEMIKRIADQPDLELIGVHCYSPDKVGRDAG
MAV_3665|M.avium_104 --MGTAPIRVFQVGSGNVGSEMIRRIATQPDLELIGVHCYSPEKIGKDTG
MMAR_1936|M.marinum_M MSARPQPIRVFQVATGNVGREMIKRLQTRPDLELIGLHCYSPDKVGADAG
MUL_2162|M.ulcerans_Agy99 ---------------------MIKRLQTRPDLELIGLHCYSPDKVGADAG
MAB_0727|M.abscessus_ATCC_1997 ----MSVIRVFQVATGNVGTEMIRRIASHPDLELAGLHCYSPEKVGRDAG
Mb1088|M.bovis_AF2122/97 ---MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVG
Rv1059|M.tuberculosis_H37Rv ---MTMSLRVIQWATGSVGVAAIKGVLQHPELELVGCWVHSAAKSGKDVG
*: : :.:*** * ::. * * *.*
MSMEG_0733|M.smegmatis_MC2_155 EIAGIGPVGVTATGTIDEIIAARPDVLTFHGVFPDEDLYIRVLEAGINIV
TH_2632|M.thermoresistible__bu EIAGIGPIGVKATGTIDEIIAAEPDVLTFHGVFPDEDLYVKVLEAGIDIV
Mflv_2754|M.gilvum_PYR-GCK ELAGLAPNGVKATGTVDEIIAARPDVVTFHGVFPDEDLYVRVLEAGINIV
Mvan_3783|M.vanbaalenii_PYR-1 EIAGLAPNGVIATGSVEEIIAAKPDVLTFHGVFPDEDLYVKVLEAGINIV
MAV_3665|M.avium_104 QFAGLAPNGVKFTGTVEEIIAAKPDVLTFHGVFPDEDLYVKVLEAGIDIV
MMAR_1936|M.marinum_M ELAGIGPIGVTATGSVSDIVAAKPDVLTFHGVFPDEDLYVKVLEAGINIV
MUL_2162|M.ulcerans_Agy99 ELAGIGPIGVTATGSVSDIVAARPDVLTFHGVFPDEDLYVKVLEAGINIV
MAB_0727|M.abscessus_ATCC_1997 ELVGLEPNGVIATGTVEEIVAAKPDVLTFHGVFPDEDLYVKVLEAGIDIV
Mb1088|M.bovis_AF2122/97 EIIGSPPLGVIATNSIDDVLALDADAVIYAPLLPSVDEVAALLRSGKNVV
Rv1059|M.tuberculosis_H37Rv EIIGSPPLGVIATNSIDDVLALDADAVIYAPLLPSVDEVAALLRSGKNVV
:: * * ** *.::.:::* .*.: : ::*. * :*.:* ::*
MSMEG_0733|M.smegmatis_MC2_155 TTADWITGWHRDTNHPHPSGRPVSELLAEACRKGSSTFYGTGMNPG-LNQ
TH_2632|M.thermoresistible__bu TTADWITGWHRDTNHPHPSGKPVTELLAEACEKGGSTFYGTGMNPG-LNQ
Mflv_2754|M.gilvum_PYR-GCK TTADWITGWHRDRNHPHHSGKPVTQLLQEACEKGGSTFYGTGMNPG-LNQ
Mvan_3783|M.vanbaalenii_PYR-1 TTADWITGWHRDRNHPHPSGKPVTQLLQEACEKGGSTFYGTGMNPG-LNQ
MAV_3665|M.avium_104 TTADWITGWHRDKNHPHPSGKPVTQLLAEAAAKGGATFYGTGMNPG-LNQ
MMAR_1936|M.marinum_M TTADWITGWHRDHNHPHPSGKPVTQLLAEACEKGGATFYGTGMNPG-LNQ
MUL_2162|M.ulcerans_Agy99 TTADWITGWHRDHNHPHPSGKPVTQLLAEACEKGGATFYGTGMNPG-LNQ
MAB_0727|M.abscessus_ATCC_1997 TTADWITGHHRDQNHPHPSGRPTTEVLQQACERGGSTFYGTGMNPG-LTQ
Mb1088|M.bovis_AF2122/97 TPLGWFYPSEKE-----------AAPLEVAAQAGNATLHGAGIGPGAVTE
Rv1059|M.tuberculosis_H37Rv TPLGWFYPSEKE-----------AAPLEVAAQAGNATLHGAGIGPGAVTE
*. .*: .:: : * *. *.:*::*:*:.** :.:
MSMEG_0733|M.smegmatis_MC2_155 ILGVVCSADVAEIENVTTIESVDVSCHHSKDTW-IEVGYGLPVDDPSIPG
TH_2632|M.thermoresistible__bu ILGVVCSADVSEIENVTTIESVDVSCHHSKDTW-VEVGYGLPVDDPEIPA
Mflv_2754|M.gilvum_PYR-GCK ILGVVCSADVAEIENVTTIESVDVSCHHSKDTW-IEVGYGQPVDDPEIPG
Mvan_3783|M.vanbaalenii_PYR-1 ILGVVCSADVAEIENVTTIESVDVSCHHSKDTW-IEVGYGQPVDDPEIPG
MAV_3665|M.avium_104 ILGVVCSADVAEIENVTTIESVDVSCHHSKDTW-IEVGYGQPVDDPEIPA
MMAR_1936|M.marinum_M ILGVVCSADVAEIENVTTIESVDVSCHHSKETW-IEVGYGQPVDDPDIPA
MUL_2162|M.ulcerans_Agy99 ILGVVCSADVSEIENVTTIESVDVSCHHSKETW-IEVGYGQPVDDPDIPA
MAB_0727|M.abscessus_ATCC_1997 ILGVIHSCDVAEIENVTVIESVDVSCHHSVDSW-EMVGYGLPVGDPSIPA
Mb1088|M.bovis_AF2122/97 LFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGP
Rv1059|M.tuberculosis_H37Rv LFPLLLSVMSTGVTFVRSEEFSDLRSYGAPDVLRYVMGFGGTPDSALTGP
:: :: * : : * * *: .: : : :*:* . ...
MSMEG_0733|M.smegmatis_MC2_155 KLEKYTRVFADSVLLMADCFGLQLD-EVKFSAELGACTKDVDLGWYQLPK
TH_2632|M.thermoresistible__bu KLEKYTRVFSDSVLMMADCFGLTLD-EVTFSAELGACTRDVDLGWYQLPK
Mflv_2754|M.gilvum_PYR-GCK KLEKYTRVFADSVYMMADCFDLTLD-EVKFSYELGACTKDVDLGWYQLPK
Mvan_3783|M.vanbaalenii_PYR-1 KLEKYTRVFADSVYMMADCFDLTLD-EVKFSYELGACTKDVDLGWYRLPK
MAV_3665|M.avium_104 KLEKYTRVFADSVYMMADCFDLTLD-EVTFSYELGACTKDVDLGWYTLPK
MMAR_1936|M.marinum_M KLEKYTRVFADSVLMMADCFDLPLD-EVKFSYELGACTKDVDLGWYTLPK
MUL_2162|M.ulcerans_Agy99 KLEKYTRVFADSVLMMADCFDLPLD-EVKFSYELGACTKDVDLGWYTLPK
MAB_0727|M.abscessus_ATCC_1997 LLEKGTRVFADGVYLMADCFGLELD-DVTFSYELGACTEDIDLGWYRLPK
Mb1088|M.bovis_AF2122/97 MQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEP
Rv1059|M.tuberculosis_H37Rv MQKILDGGFLQSVRLCVDRLGFAADPQIRTSQEVAVATAPIDSPIGVIEP
: * :.* : .* :.: * :: * *:...* :* :
MSMEG_0733|M.smegmatis_MC2_155 GSLGGNYIKYQGMVDGVPRIETHLEWQMTP-HTDPHWDIKGC---YITQI
TH_2632|M.thermoresistible__bu GSLGGSYIKYQGMVDGVPRIETHLEWQMTP-HTDPHWDIKGC---YITQI
Mflv_2754|M.gilvum_PYR-GCK GSLGGNYIRYQGMVDGVPRVETHLEWQMTP-HTDPSWDIKGC---YITQI
Mvan_3783|M.vanbaalenii_PYR-1 GSLGGNYIKYQGMVDGVPRVETHLEWQMTP-HTDPSWDIKGC---YITQI
MAV_3665|M.avium_104 GSLGGNYIKYQGMVDGVPRVETHLEWQMTP-HTDPSWNVKGC---YITQI
MMAR_1936|M.marinum_M GSLGGNYLKYQGMVGGVPRVETHLEWQMTP-HTDPSWNIKGC---YITQI
MUL_2162|M.ulcerans_Agy99 GSLGGNYLKYQGMVGGVPRVETHLEWQMTP-HTDPSWNIKGC---YITQI
MAB_0727|M.abscessus_ATCC_1997 GSLGANYLKYQGIVGGVPKVEVHVEWQMTP-KTEPHWNVKGC---YITKI
Mb1088|M.bovis_AF2122/97 GQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGPAGERYEIEV
Rv1059|M.tuberculosis_H37Rv GQVAGRRFHWEALVEDTVVVQIAVNWLMGSENLDPPWSFGPAGERYEIEV
*.:.. ::::.:* .. :: ::* * . : :* *.. . * ::
MSMEG_0733|M.smegmatis_MC2_155 KGDPCVYNKHMIFPKPGVDLSDPDSFASIGMTVTGMPALNAIASVVAAPP
TH_2632|M.thermoresistible__bu KGDPCVYNKHMIFPKPGVDLSDPDSFASIGMTVTGLPALNAIRSVVAAPP
Mflv_2754|M.gilvum_PYR-GCK KGDPNIYNKHMIFPKPGVDLSDPASFASIGMTVTGMPALASITSVVAARP
Mvan_3783|M.vanbaalenii_PYR-1 KGDPNIYNKHMIFPKPGVDLSDPANFASIGMTVTGMPALHAIKSVVAARP
MAV_3665|M.avium_104 KGDPCVYNKHMIFPKPGVDLSNPDNFASIGMTVTGMPALAAIRSVVAAPP
MMAR_1936|M.marinum_M KGDPCIYNKHMIFPKAGVDLSNPENFASIGMTVTGMPALNSIKSVVAARS
MUL_2162|M.ulcerans_Agy99 KGDPCIYNKHMIFPKAGVDLSNPDNFASIGMTVTGMPALNSIKSVVAARP
MAB_0727|M.abscessus_ATCC_1997 QGDPCVYSKHMVIPKPGTDFTDPAAFASVGMTVTGLPALNAIRSVIDAPP
Mb1088|M.bovis_AF2122/97 RGSP---DTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPA
Rv1059|M.tuberculosis_H37Rv RGSP---DTCVTIKGWQPQTVAAGLKSNPGIVATAAHCVNAIPATCAAPA
:*.* .. : : : . :. *:..*. .: :* :. * .
MSMEG_0733|M.smegmatis_MC2_155 GLLTSADVPLRGFAGRFKL--
TH_2632|M.thermoresistible__bu GLLTSADVPLRGFAGRFTL--
Mflv_2754|M.gilvum_PYR-GCK GIITSADLPLRGFAGRFKL--
Mvan_3783|M.vanbaalenii_PYR-1 GLMTSADLPLRGFAGRFKL--
MAV_3665|M.avium_104 GLLTSADLPLRGFAGRFKK--
MMAR_1936|M.marinum_M GLITSAELPLRGFAGRFKN--
MUL_2162|M.ulcerans_Agy99 GLITSAELPLRGFAGRFKN--
MAB_0727|M.abscessus_ATCC_1997 GILTSADLPLRGFAGRFK---
Mb1088|M.bovis_AF2122/97 GIQSFFDLPLITGRAAPGLAR
Rv1059|M.tuberculosis_H37Rv GIQSFFDLPLITGRAAPGLAR
*: : ::** .