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M. thermoresistible (build 8) TH_2519 (-)

annotation: putative conserved hypothetical protein
coordinates: 889716 - 891134
length: 473

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2519--100% (473)putative conserved hypothetical protein
M. thermoresistible (build 8)TH_2715-1e-5335.73% (459) PUTATIVE conserved hypothetical protein
M. thermoresistible (build 8)TH_3688-5e-3831.84% (490) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3842PE_PGRS622e-1025.99% (404) PE-PGRS family protein
M. gilvum PYR-GCKMflv_1753-5e-2427.21% (452) hypothetical protein Mflv_1753
M. tuberculosis H37RvRv3812PE_PGRS622e-1025.99% (404) PE-PGRS family protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2679-7e-0824.27% (515) hypothetical protein MAB_2679
M. marinum MMMAR_2459-6e-1330.97% (226) PE-PGRS family protein
M. avium 104-----
M. smegmatis MC2 155MSMEG_5322-3e-3027.97% (479) hypothetical protein MSMEG_5322
M. ulcerans Agy99MUL_1639-1e-1326.33% (300) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_3971-6e-3932.36% (411) hypothetical protein Mvan_3971

CLUSTAL 2.0.9 multiple sequence alignment


Mb3842|M.bovis_AF2122/97            MSFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAA-AAADDVSI
Rv3812|M.tuberculosis_H37Rv         MSFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAA-AAADDVSI
MMAR_2459|M.marinum_M               MSFLLVQPEMVSAATESLTAIRSALGEVSAAVAGPTTAVVA-AAGDEVSA
MUL_1639|M.ulcerans_Agy99           MSFLLVQPEMVSAATESLTAIRSALGEVSAAVAGPTTAVVA-AAGDEVSA
Mvan_3971|M.vanbaalenii_PYR-1       ----------------MHVAVRSPLATGVALVGAGAIALTP-VHPSLPDI
MSMEG_5322|M.smegmatis_MC2_155      ----------------MQQAVRSYLTAGVAFAGAGVIAVSP-VAPLPPDI
TH_2519|M.thermoresistible__bu      ----------------MYARLRSFTTAGVALVGAGIITVAPTIAPPVPDI
Mflv_1753|M.gilvum_PYR-GCK          ----------------MYTTLRPYATAGVAMLGASAIAIAP---VVVTPT
MAB_2679|M.abscessus_ATCC_1997      ----------------MDRTANPLFKAGMAAITATALIVAPAVTPPTRQS
                                                          .      *   .    : .         

Mb3842|M.bovis_AF2122/97            AVSQLFGRYGQEFQTVSNQLAAFHTEFVRTLNRGAAAYLNTESANG----
Rv3812|M.tuberculosis_H37Rv         AVSQLFGRYGQEFQTVSNQLAAFHTEFVRTLNRGAAAYLNTESANG----
MMAR_2459|M.marinum_M               AISQVFGAYGQEFQALNAQAAAFQAEFEGLLSGGAAAYVSAEALNSSVFG
MUL_1639|M.ulcerans_Agy99           AISQVFGAYGQEFQALNAQAAAFQAEFEGLLSGGAAAYVSAEALNSSVFG
Mvan_3971|M.vanbaalenii_PYR-1       SVPAVS-SMAVQLTAQPNPIALWTEVFAGAIN------------------
MSMEG_5322|M.smegmatis_MC2_155      TERAQS-SAGVALSALANPIDGYAAAFTAALK------------------
TH_2519|M.thermoresistible__bu      TVEAKYSSASVQPTAFANPLDAYGQLFQNTAE------------------
Mflv_1753|M.gilvum_PYR-GCK          LPDLKVVSTGVQLNAAIDPLTPLLELFNSSEV------------------
MAB_2679|M.abscessus_ATCC_1997      IPLPDIRSASVRLSSLAFTPRAAEVPASPLAALKLSLSPASAAPASPLKR
                                             .    :                                   

Mb3842|M.bovis_AF2122/97            --------------GQLFG--QIEAGQRAVSAAAAAAPG-----------
Rv3812|M.tuberculosis_H37Rv         --------------GQLFG--QIEAGQRAVSAAAAAAPG-----------
MMAR_2459|M.marinum_M               PPMQELLKVVNAPTQMLLGRSLIADGANATVAGGDGRPGGILMGKGGDGA
MUL_1639|M.ulcerans_Agy99           PPMQELLKVVNAPTQMLLGRSLIADGANATAAGGDGRPGGILMGKGGDGA
Mvan_3971|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5322|M.smegmatis_MC2_155      --------------------------------------------------
TH_2519|M.thermoresistible__bu      --------------------------------------------------
Mflv_1753|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997      APLGQLATAVQPRAAAAPLPTPVSAPTQPDAATASSPVVASSLTN-----
                                                                                      

Mb3842|M.bovis_AF2122/97            -GAYGQLVAN-TATNLESLYGAWSANPFPFLRQIIANQQVYWQQ------
Rv3812|M.tuberculosis_H37Rv         -GAYGQLVAN-TATNLESLYGAWSANPFPFLRQIIANQQVYWQQ------
MMAR_2459|M.marinum_M               PGGPGQPGGNGGAAGLIGTGGAGGKEAPSMPGGLGGRGGLLWGDGGKGGD
MUL_1639|M.ulcerans_Agy99           PGGPGQPGGNGGAAGLIGTGGAGGKGAPSMPGGLGGRGGLLWGDGGKGGD
Mvan_3971|M.vanbaalenii_PYR-1       --------------NIGGLGEDLLSDPFPVLNQILRNQFGYLQT------
MSMEG_5322|M.smegmatis_MC2_155      --------------NAEALTARIAAAPAPILSNIVRNQVNSAAG------
TH_2519|M.thermoresistible__bu      --------------NLQGLFSVLSANPAPILQQIVANQVENVEA------
Mflv_1753|M.gilvum_PYR-GCK          --------------NVAALVDAWLEAPAPILQQIIANQIGYLGQ------
MAB_2679|M.abscessus_ATCC_1997      -GIDQAYQFIQYWVDYGVDLAQWGAGFVPVIGGLVSAQIGIVYDN-----
                                                  .             ..   :                

Mb3842|M.bovis_AF2122/97            ------------IAAALANAVQNFPALVANLP---AAIDAAVQQFLAFNA
Rv3812|M.tuberculosis_H37Rv         ------------IAAALANAVQNFPALVANLP---AAIDAAVQQFLAFNA
MMAR_2459|M.marinum_M               GGAPVYDAWGYLLAEAGTGGAGGLPGMFGGLPGVAGAWGGEVPTALAAPM
MUL_1639|M.ulcerans_Agy99           GGAPVYDAWGYLLAEAGTGGAGGLPGIFGGLPGVAGAWGGEVPTALAAPM
Mvan_3971|M.vanbaalenii_PYR-1       ------------IGEAGKGIIDGLVEYASPDN----------PFGLQAGI
MSMEG_5322|M.smegmatis_MC2_155      ------------VATFAEVFTSSVITALADTP---------------EQL
TH_2519|M.thermoresistible__bu      ------------FFPELVSTLQSLAYAFSPEN----------PQGVFFMI
Mflv_1753|M.gilvum_PYR-GCK          ------------LPDIGAILAQMGTNLVAGLR-----------------S
MAB_2679|M.abscessus_ATCC_1997      -----------LVRPIANSFVYNLVDPILNDPSFSNIVNSFGRFGSDIVN
                                                .                                     

Mb3842|M.bovis_AF2122/97            AYYIQQIISSQIG--FAQLFATTVGQGVTSVIAGWPNLAAELQLAFQQLL
Rv3812|M.tuberculosis_H37Rv         AYYIQQIISSQIG--FAQLFATTVGQGVTSVIAGWPNLAAELQLAFQQLL
MMAR_2459|M.marinum_M               ALSAAASSPAAVGGAYQTLFDNTWTN-LQAIGATWNADPAPFLSQFIANQ
MUL_1639|M.ulcerans_Agy99           ALSAAASSPAAVGGAYQTLFDNTWTN-LQAIGATWNADPAPFLSQFIANQ
Mvan_3971|M.vanbaalenii_PYR-1       RDAVAQFKAGDIGAAFTTLASTVITG-PIIVGAGLPLLMSGLLEVPVKMA
MSMEG_5322|M.smegmatis_MC2_155      QSAVEKFSAGDVTGALETVLQTVLGP----VVNGVVDTLLFNPDVWAGLQ
TH_2519|M.thermoresistible__bu      ETAVDLLRAGEIQQAFDVLAMG------PVIVIGLPLLMGNLVPAAIDLI
Mflv_1753|M.gilvum_PYR-GCK          PFAEDPSTLEPLHASIYELIVDGIPG----AIEPAPPQLVPLLEFTTTYL
MAB_2679|M.abscessus_ATCC_1997      SVINFAWAEARYFLPPLPPLPGLALQTTTDANGAAPTSVHEALVPFTKAF
                                                                                      

Mb3842|M.bovis_AF2122/97            VGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTIS------------
Rv3812|M.tuberculosis_H37Rv         VGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTIS------------
MMAR_2459|M.marinum_M               QTYANTVFTSLSNSVQDFGAGLVALPAAYQGAFQALMTG-----------
MUL_1639|M.ulcerans_Agy99           QTYANTVFTSLSNSVQDFGAGLVALPAAYQGAFQALMTG-----------
Mvan_3971|M.vanbaalenii_PYR-1       QNFTDAVAALLNPTTAVPLIT--AALGPILGPFSALGAS-----------
MSMEG_5322|M.smegmatis_MC2_155      NAIRQPVANTLSVIDLLAEPEVYNVLGPLLAPVQLLTD------------
TH_2519|M.thermoresistible__bu      GKPLQNLTNVITSFATDPGTLLGLVLAPLNPVMALVGGTG----------
Mflv_1753|M.gilvum_PYR-GCK          SGVLVGLAGLVMNPVLALGGGIHSVFQSLIGEDADLGAAI----------
MAB_2679|M.abscessus_ATCC_1997      KDAEAHFAEALGLTKPDPKSAALEKTGTAAQTGESLKETTGESVQEEGKT
                                              :                                       

Mb3842|M.bovis_AF2122/97            -----VTAKPKLLGP----------LGDLFTIMTIPAQEAQYFTNLMPPS
Rv3812|M.tuberculosis_H37Rv         -----VTAKPKLLGP----------LGDLFTIMTIPAQEAQYFTNLMPPS
MMAR_2459|M.marinum_M               ----NVSGAVEILGKGYLGL---VFNGFDYTNVPVVTVQGALGDLLPITT
MUL_1639|M.ulcerans_Agy99           ----NVSGAVEILGKGYLGL---VFNGFDYTNVPVVTVQGALGDLLPMTT
Mvan_3971|M.vanbaalenii_PYR-1       -----VQDFVEALGS-----------GDVLDAITTVINVPAKLVGAALNG
MSMEG_5322|M.smegmatis_MC2_155      -----LTDAVGAAGDDVFAG---IKTGDLEKVANAVINLGPNFTYALLNG
TH_2519|M.thermoresistible__bu      ---LALQNIVEAAGDPAQLVS--ALIAAPATILDAALNGYTPDGGLLLGG
Mflv_1753|M.gilvum_PYR-GCK          ---NTLINIPTAMADAFLNGGQSMVVTPLLTALGLELPIPGMEVELNFGG
MAB_2679|M.abscessus_ATCC_1997      AETGAATGTKEALDRKESAEG-KASANDKATAVAEKTKAGDKATTESREP
                                                                                      

Mb3842|M.bovis_AF2122/97            ILRD---------------MSQNFTNVLTTLSNPNIQAVASFDIATTAGT
Rv3812|M.tuberculosis_H37Rv         ILRD---------------MSQNFTNVLTTLSNPNIQAVASFDIATTAGT
MMAR_2459|M.marinum_M               IPGQ---------------ISQNMTNVLQTVTDTSIMANISLLSPSFT--
MUL_1639|M.ulcerans_Agy99           IPGQ---------------ISQNMTNVLQTVTDTSIMANISLLNPSFT--
Mvan_3971|M.vanbaalenii_PYR-1       FTDE---------------GGNFFAGILTVSDDPFSAGLLQTLLVTVPRA
MSMEG_5322|M.smegmatis_MC2_155      APGMPGFSAG-------LLGPQGVVAGLLTLRDMVADAIAPATTAAKTAA
TH_2519|M.thermoresistible__bu      LLGSGVDGNTGGTIALLHGVRVAIAQVLGYTPNPVSTMMSTHTVSTETPV
Mflv_1753|M.gilvum_PYR-GCK          LLSPGGSMFN---------SLNLVFGPGDELPGQGAGLIGSLVALSKVIA
MAB_2679|M.abscessus_ATCC_1997      VTTATEAAKES----TKDSVKDAAVPGVAADSDAASGNLTKGTLAAKETG
                                                                    .            :    

Mb3842|M.bovis_AF2122/97            LSTFFGVPLVLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGALI
Rv3812|M.tuberculosis_H37Rv         LSTFFGVPLVLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGALI
MMAR_2459|M.marinum_M               ----TGFPLTLALDALGAPIVTGQAALQSATTFIDAVQAGDVAGAFGAIV
MUL_1639|M.ulcerans_Agy99           ----TGFPLTLALDALGAPIVTGQAALQSATTFIDAVQAGDVAGAFGAIV
Mvan_3971|M.vanbaalenii_PYR-1       VAAALGAEDAPARVAGALDEVSSPISEPAAAVTVSVTETDSATTEVDSAT
MSMEG_5322|M.smegmatis_MC2_155      GTAAVAEPAALTRASVTLDVPKALVGPETPAAGAVTTPAEATTDAPAAAT
TH_2519|M.thermoresistible__bu      EIDSLDEGDLVENQSAGSQATAETNDGPAIREAGVQRLAAPTEPTVESGL
Mflv_1753|M.gilvum_PYR-GCK          KAIGWDGEGNPLAPPLTPQSTLREATDTSLASVSTVTLETGTAAVVDAAE
MAB_2679|M.abscessus_ATCC_1997      NQQQSATDGKPSPSSAPADKPDKPVKPKVPAASTTEHGSISAQGIVRGPV
                                                  .                                .  

Mb3842|M.bovis_AF2122/97            DAPA--HALDGFLNSATV-LDTPILVPTGL-PSPLPPTVGITLHLPFDGI
Rv3812|M.tuberculosis_H37Rv         DAPA--HALDGFLNSATV-LDTPILVPTGL-PSPLPPTVGITLHLPFDGI
MMAR_2459|M.marinum_M               DAPA--VIANGFLNGE----GTITLDLPTY-LSPISGTESLTSAIPIGGI
MUL_1639|M.ulcerans_Agy99           DAPA--VIANGFLNGE----ETITLDLPTY-LSPISGTESLTSAIPIGGI
Mvan_3971|M.vanbaalenii_PYR-1       EVPA--AEPE----------ETPTAPAEEA-PVEEAPAEERADTSAEDGA
MSMEG_5322|M.smegmatis_MC2_155      DTST--KQAPSATDAASASAASEAKPVADD-SEEAITTPAKPSTVAKPKK
TH_2519|M.thermoresistible__bu      EADS--KSAEDGDTSVSAAEETTGAKEASLTAVESRASLVRDSLRAVPGE
Mflv_1753|M.gilvum_PYR-GCK          DAES--ASGGSAPESSTAPAVSEDQDGEGVAEEDDTAAYDEAVKDEVETV
MAB_2679|M.abscessus_ATCC_1997      SQSTSGQSGPSASTPKTADSKVSSSGASGFQTSDTGTPESKMSDTKTATG
                                    .  :                                 .            

Mb3842|M.bovis_AF2122/97            LVPPHPVTATISFPGAPVPIPGFPTTVTVF-GTPFMGMAPLLINYIPQQL
Rv3812|M.tuberculosis_H37Rv         LVPPHPVTATISFPGAPVPIPGFPTTVTVF-GTPFMGMAPLLINYIPQQL
MMAR_2459|M.marinum_M               LTPLQPVDSTIVFRVLPHTPP-VTQHITLG-GTEFGGLIPGLQSAS-AQL
MUL_1639|M.ulcerans_Agy99           LTPLQPVESTIVFRVLPHTPP-VTQHITLG-GTEFGGLIPGLQSAS-AQL
Mvan_3971|M.vanbaalenii_PYR-1       VQGDAEVTDGEPVVDEAADGDDAPTSDDTE-ADDAGADEGTPSDTSAGDA
MSMEG_5322|M.smegmatis_MC2_155      VNAVKDIRNGIRGAIKNVRNGVKDAVAGLS-GKKAKPAKPVKQESSTKSG
TH_2519|M.thermoresistible__bu      TVADGAKPREQSGPVRGVRGQLRTTAPSVQNGVAATSAVGERVSTNAKDA
Mflv_1753|M.gilvum_PYR-GCK          EEEVEEVAEEAEEVEEAEVADTDVETETETETEKTEAEKTEKTEAEKTET
MAB_2679|M.abscessus_ATCC_1997      TTAGTKATETKPKAAETKPSDAKSSGSTTSGTKSPGTTAHDSANKPSASA
                                                                               .    . 

Mb3842|M.bovis_AF2122/97            ALAIKPAA-------------
Rv3812|M.tuberculosis_H37Rv         ALAIKPAA-------------
MMAR_2459|M.marinum_M               ADAIKLS--------------
MUL_1639|M.ulcerans_Agy99           ADAIKLS--------------
Mvan_3971|M.vanbaalenii_PYR-1       DSTDSSAA-------------
MSMEG_5322|M.smegmatis_MC2_155      GSESDGGGSGGGAE-------
TH_2519|M.thermoresistible__bu      SGSSTSTATGSNDRGPGDADE
Mflv_1753|M.gilvum_PYR-GCK          ESGTDAGAE------------
MAB_2679|M.abscessus_ATCC_1997      SSAAKSGGEGSKSSSGSHR--