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HAMLRAIAALTVAVAAVLAPVTAPTAGAQGVEMLMVPSAAMGRSIPVAFQGGGPHAVVLLDAFNAAPDVS NWVTAGNAMGTLSGRGISVAAPAGGAWSMYTNWEQDGSKQWETFLADELPNWLAANKGLAPNGHAIVGAA QGGTGALTMATFHPDRYRFAGSLSGFLTPSATALNGAITAGLARFGGVDTRNMWGLPQLGRWKWHDPDVH AQLLVNNNTRLWIYSPATTTCTDVPAMIGYCDQAQGSNRTFYQHYRGIGGGNGHFDFPTSGNHDWGSWSG QLAAMSGELVATIG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5644 | - | - | 100% (295) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_2954 | - | 5e-62 | 42.81% (299) | putative esterase |
| M. vanbaalenii PYR-1 | Mvan_1190 | - | 1e-55 | 40.13% (304) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3833c | fbpD | 1e-116 | 67.35% (294) | secreted MPT51/MPB51 antigen protein FBPD (MPT51/MPB51 |
| M. gilvum PYR-GCK | Mflv_1165 | - | 1e-157 | 87.29% (299) | putative esterase |
| M. tuberculosis H37Rv | Rv3803c | fbpD | 1e-116 | 67.35% (294) | secreted MPT51/MPB51 antigen protein FBPD (MPT51/MPB51 |
| M. leprae Br4923 | MLBr_00098 | fbpC | 1e-113 | 67.82% (289) | antigen 85C, mycolyltransferase |
| M. abscessus ATCC 19977 | MAB_0175 | - | 7e-58 | 41.35% (312) | antigen 85-C precursor |
| M. marinum M | MMAR_5367 | fbpD | 1e-114 | 65.64% (291) | secreted Mpt51/Mpb51 antigen protein FbpD |
| M. avium 104 | MAV_0215 | - | 1e-116 | 68.47% (295) | antigen 85-C |
| M. smegmatis MC2 155 | MSMEG_6396 | - | 1e-133 | 76.61% (295) | antigen 85-C |
| M. thermoresistible (build 8) | TH_2468 | - | 1e-132 | 78.29% (281) | PUTATIVE putative esterase |
| M. ulcerans Agy99 | MUL_4986 | fbpD | 1e-113 | 65.29% (291) | secreted Mpt51/Mpb51 antigen protein FbpD |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5644|M.vanbaalenii_PYR-1 ------MHAMLRAIAALTVAV---AAVLAPVT--APT--AGAQGVEMLMV
Mflv_1165|M.gilvum_PYR-GCK ------MRGMVRAVAAVAMAALFWSGAVAPFTPATPV--ARAQGVEMLMV
MSMEG_6396|M.smegmatis_MC2_155 ------MRRGLSLVRALMLTVVLAAGLWTVSATSGAP--ARADGVEYLMV
Mb3833c|M.bovis_AF2122/97 ------MKGRSALLRALWIAALSFG-LGGVAVAAEPT--AKAAPYENLMV
Rv3803c|M.tuberculosis_H37Rv ------MKGRSALLRALWIAALSFG-LGGVAVAAEPT--AKAAPYENLMV
MMAR_5367|M.marinum_M ------MRGVSVVIRLLCVAVLSVT-LGGITVATGSTGKANAAPYETLMV
MUL_4986|M.ulcerans_Agy99 --MEVDMRGVSVVTRLLCVAVLSVT-LGGITVATGSTGKANAAPYETLMV
MLBr_00098|M.leprae_Br4923 ------MRGLSAVVRVLCVAALAVGVFAAAVLLAGTAGNAKAAGYESLMV
MAV_0215|M.avium_104 -MDMTVVRGVSALLRVFCIAVLAAG-LGVALQPAAVTGAARAAGYESLMV
TH_2468|M.thermoresistible__bu ------MNLLSVFFRMMCAAVLAAV---GVTVSTATA--TAQPAVEQLMV
MAB_0175|M.abscessus_ATCC_1997 MSVRVKARRVLSALLAAFVMPVSMAAAMTINPATAHAFSREGLPVEYLDV
. * * *
Mvan_5644|M.vanbaalenii_PYR-1 PSAAMGRSIPVAFQGGGPHAVVLLDAFNAAPDVSNWVTAGNAMGTLSGRG
Mflv_1165|M.gilvum_PYR-GCK PSAAMGRAIPVAFQGGGPHAVVLLDAFNAAPDVSNWVTAGNAMNTLSGLG
MSMEG_6396|M.smegmatis_MC2_155 PSAAMGRDIPVAFQAGGPHAVFLLDAFNAAPDVSNWVNAGSAMSTLAGRG
Mb3833c|M.bovis_AF2122/97 PSPSMGRDIPVAFLAGGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKG
Rv3803c|M.tuberculosis_H37Rv PSPSMGRDIPVAFLAGGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKG
MMAR_5367|M.marinum_M PSGAMGRDIPVAFLAGGPHAAYLLDAFNAGPDVSNWVTAGNAMNTLGGKG
MUL_4986|M.ulcerans_Agy99 PSGAMGRDIPVAFLAGGPHAAYLLDAFNAGPDVSNWVTAGNAMNTLGGKG
MLBr_00098|M.leprae_Br4923 PSNAMGRDIPVAFMAGGPHAVYLLDAFNAALDVSNWVTAGNAMTTLGGRG
MAV_0215|M.avium_104 PSAAMGRDIPVAFLAGGPHAVYLLDAFNAAPDVSNWVTAGNAMNTLGGKG
TH_2468|M.thermoresistible__bu PSAAMGRDIPVSFMAGGPHAVVLLDAFNAAPDVSNWVTVGNAMNTLAGKG
MAB_0175|M.abscessus_ATCC_1997 YSNSMGRNIRVEFQGGGPKAVYLLDGLRAQDDFNGWDINTAAFEWFYQSG
* :*** * * * .***:*. ***.:.* *...* *: : *
Mvan_5644|M.vanbaalenii_PYR-1 ISVAAPAGGAWSMYTNWEQDGSK-------QWETFLADELPNWLAANKGL
Mflv_1165|M.gilvum_PYR-GCK ISVAAPAGGAWSMYTNWEQDGSK-------QWETFLADELPNWLAANKGL
MSMEG_6396|M.smegmatis_MC2_155 ISVAAPAGGAWSLYTNWEQDGSK-------QWETFLTAELPGWLAANKGL
Mb3833c|M.bovis_AF2122/97 ISVVAPAGGAYSMYTNWEQDGSK-------QWDTFLSAELPDWLAANRGL
Rv3803c|M.tuberculosis_H37Rv ISVVAPAGGAYSMYTNWEQDGSK-------QWDTFLSAELPDWLAANRGL
MMAR_5367|M.marinum_M ISVVAPAGGAFSMYTDWEQDGSK-------QWDTFLSSELPDWLAANKGL
MUL_4986|M.ulcerans_Agy99 ISVVAPAGGAFSMYTDWEQDGSK-------QWDTFLSSELPDWLAANKGL
MLBr_00098|M.leprae_Br4923 ISVVAPAGGAYSMYTNWENDGSK-------QWDTFLSSELPDWLATKRGL
MAV_0215|M.avium_104 ISVVAPAGGAWSMYTNWEQDGSK-------QWDTFLSSELPDWLAANKGL
TH_2468|M.thermoresistible__bu ISVVAPAGGAWSLYTNWENDGSK-------QWETFLANELPDWLAANKGL
MAB_0175|M.abscessus_ATCC_1997 ISVVMPVGGQSSFYTDWYSPSALNKQPYTYKWETFLTQELPAYLATNKQI
***. *.** *:**:* . .: :*:***: *** :**::: :
Mvan_5644|M.vanbaalenii_PYR-1 APNGHAIVGAAQGGTGALTMATFHPDRYRFAGSLSGFLTPSATALNGAIT
Mflv_1165|M.gilvum_PYR-GCK APGGHGIVGAAMGGTGALTMATFHPDRYRFAGSLSGFLTPSATAMNGAIT
MSMEG_6396|M.smegmatis_MC2_155 APDGHAVVGAAQGGTAAVTLAAFHPGMFRFAGSLSGFLTPSATTLNGAIT
Mb3833c|M.bovis_AF2122/97 APGGHAAVGAAQGGYGAMALAAFHPDRFGFAGSMSGFLYPSNTTTNGAIA
Rv3803c|M.tuberculosis_H37Rv APGGHAAVGAAQGGYGAMALAAFHPDRFGFAGSMSGFLYPSNTTTNGAIA
MMAR_5367|M.marinum_M APGGHAAVGASQGGYGAMALAAFHPDRFGFAGSLSGFLYPSSTTTNGAIL
MUL_4986|M.ulcerans_Agy99 APGGHAAVGASQGGYGAMALAAFHPDRFGFAGSLSGFLYPSSTTTNGAIL
MLBr_00098|M.leprae_Br4923 APDGHAAVGASQGGYAALALAAFHPDRFGFAGSLSGFVYPSSTNYNGAIL
MAV_0215|M.avium_104 APGGHAAVGASQGGYGAMALAAFHPDRFGFAGSLSGFLYPSSTNYNGAIL
TH_2468|M.thermoresistible__bu APGGHGIVGASQGGTAALTLAAFYPNRYRYAGSMSGFLTPSATALNGAIT
MAB_0175|M.abscessus_ATCC_1997 SATGNGVVGLSMSGGAALILAAFHPAQFRFAGSLSGFLNPSTIFMTNAIR
:. *:. ** : .* .*: :*:*:* : :***:***: ** ..**
Mvan_5644|M.vanbaalenii_PYR-1 AGLARFGGVDTRNMWGLPQLGRWKWHDPDVHAQLLVNNNTRLWIYSP---
Mflv_1165|M.gilvum_PYR-GCK DGLARFGGLDIRNMWGLPQLGRWKWHDPDVHSQLLANNNTRLWIYSP---
MSMEG_6396|M.smegmatis_MC2_155 AGLARFGNVDANRMWGPPQFGRWKWHDPAVHVQLLADSNTRLWVYSP---
Mb3833c|M.bovis_AF2122/97 AGMQQFGGVDTNGMWGAPQLGRWKWHDPWVHASLLAQNNTRVWVWSP---
Rv3803c|M.tuberculosis_H37Rv AGMQQFGGVDTNGMWGAPQLGRWKWHDPWVHASLLAQNNTRVWVWSP---
MMAR_5367|M.marinum_M AGMQQFGGVDGNGMWGAPQLGRWKWHDPWVHAALLAQNNTRVWVWSP---
MUL_4986|M.ulcerans_Agy99 AGMQQFGGVDGNGMWGAPQLGRWKWHDPWVHAALLAQNNTRVWVWSP---
MLBr_00098|M.leprae_Br4923 AGLQQFGGIDGNGMWGAPQLGRWKWHDPYVHASLLAQNNTRVWVYSP---
MAV_0215|M.avium_104 AGLQQYGGVDGNGMWGAPQLGRWKWHDPYVHASLLAQNNTRVWVWSP---
TH_2468|M.thermoresistible__bu AGLQRFGGVETTNMWGLPQAGRWKWRDPDVHAQLLVNNNTRLWVFSP---
MAB_0175|M.abscessus_ATCC_1997 VAMLDAGSYSVDNMWGPPWDPAWRRNDPTVQAQALVAAGTRLYIYCAPGG
.: *. . *** * *: .** *: *. .**::::..
Mvan_5644|M.vanbaalenii_PYR-1 ATTTCTDVPAMIGYCDQAQGS-----NRTFYQHYRGIGGGNGHFDFPTSG
Mflv_1165|M.gilvum_PYR-GCK GTTTCTDVPAMIGYCDQAQGS-----NRTFYQHYRAVGGSNGHFDFPTSG
MSMEG_6396|M.smegmatis_MC2_155 GTLTCSDPAAMIGYCDQAQGS-----NRQFYSDYRRVGGSNGHFDFPASG
Mb3833c|M.bovis_AF2122/97 TNPGASDPAAMIGQAAEAMGN-----SRMFYNQYRSVGGHNGHFDFPASG
Rv3803c|M.tuberculosis_H37Rv TNPGASDPAAMIGQAAEAMGN-----SRMFYNQYRSVGGHNGHFDFPASG
MMAR_5367|M.marinum_M TNPGASDPAAMIGQAGAAMGD-----SRSFYQQYRNVGGHNGHFDFPGGG
MUL_4986|M.ulcerans_Agy99 TNPGASDPAAMIGQAGAAMGD-----SRSFYQQYRNVDGHNGHFDFPGGG
MLBr_00098|M.leprae_Br4923 MTMGG-DIDAMIGQAVASMGS-----SREFYQQYRSVGGHNGHFDFSGGG
MAV_0215|M.avium_104 TNMGG-DDAAMIGQAGAAMGS-----SREFYQQYRSNGGHNGHFDFPGGG
TH_2468|M.thermoresistible__bu QTLTAADPAAMIGYADQAQGS-----NRTFYAHYRQIGGRNGHFDFPTSG
MAB_0175|M.abscessus_ATCC_1997 STPIDDNTDAGVALSASSLESLAVAGNKAFQQAYTAAGGRNANFVFPASG
. : * :. . : . .: * * .* *.:* *. .*
Mvan_5644|M.vanbaalenii_PYR-1 NHDWGSWSGQLAAMSGELVATIG-
Mflv_1165|M.gilvum_PYR-GCK NHDWGSWSGQLAAMTGELVATIR-
MSMEG_6396|M.smegmatis_MC2_155 QHDWGSWAPQLAYMSGELVATIK-
Mb3833c|M.bovis_AF2122/97 DNGWGSWAPQLGAMSGDIVGAIR-
Rv3803c|M.tuberculosis_H37Rv DNGWGSWAPQLGAMSGDIVGAIR-
MMAR_5367|M.marinum_M DNGWGSWSAQLGAMSGDIVGAIR-
MUL_4986|M.ulcerans_Agy99 DNGWGSWSAQLGAMSGDIVGAIR-
MLBr_00098|M.leprae_Br4923 DNGWGAWAPQLAAMSGDIVGAIR-
MAV_0215|M.avium_104 DNGWGSWAGQLGAMSGDIVGAIR-
TH_2468|M.thermoresistible__bu DHGWSSWGPELGKMSGDLVAAIR-
MAB_0175|M.abscessus_ATCC_1997 NHSWPYWGQQLQALKGDLIATLNG
::.* *. :* :.*:::.::