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M. thermoresistible (build 8) TH_2259 (deoD)

annotation: PROBABLE PURINE NUCLEOSIDE PHOSPHORYLASE DEOD (INOSINE PHOSPHORYLASE) (PNP)
coordinates: 4412285 - 4413079
length: 265

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2259 deoD - 100% (265) PROBABLE PURINE NUCLEOSIDE PHOSPHORYLASE DEOD (INOSINE PHOSPHORYLASE) (PNP)
M. thermoresistible (build 8) TH_0435 pnp 7e-10 28.88% (232) PROBABLE 5'-METHYLTHIOADENOSINE PHOSPHORYLASE PNP (MTA

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3335 deoD 1e-113 78.46% (260) purine nucleoside phosphorylase
M. gilvum PYR-GCK Mflv_4828 - 1e-117 78.41% (264) purine nucleoside phosphorylase
M. tuberculosis H37Rv Rv3307 deoD 1e-113 78.46% (260) purine nucleoside phosphorylase
M. leprae Br4923 MLBr_00707 deoD 1e-104 71.92% (260) purine nucleoside phosphorylase
M. abscessus ATCC 19977 MAB_3660 - 1e-112 76.81% (263) purine nucleoside phosphorylase
M. marinum M MMAR_1219 deoD 1e-113 76.34% (262) purine nucleoside phosphorylase DeoD
M. avium 104 MAV_4284 - 1e-116 78.08% (260) purine nucleoside phosphorylase
M. smegmatis MC2 155 MSMEG_1701 - 1e-125 84.09% (264) purine nucleoside phosphorylase
M. ulcerans Agy99 MUL_2673 deoD 1e-113 75.95% (262) purine nucleoside phosphorylase
M. vanbaalenii PYR-1 Mvan_1610 - 1e-118 78.41% (264) purine nucleoside phosphorylase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1219|M.marinum_M               -------------------MTGPQPDPDELARRAAQVIGERTGIAEHDVA
MUL_2673|M.ulcerans_Agy99           -------------------MTGPQPDPDELARRAAQVIGERTGIAEHDVA
MLBr_00707|M.leprae_Br4923          -------------------MTYTLLDPDELARRAAQVIGERTGILKHDVA
Mb3335|M.bovis_AF2122/97            -------------------MADPRPDPDELARRAAQVIADRTGIGEHDVA
Rv3307|M.tuberculosis_H37Rv         -------------------MADPRPDPDELARRAAQVIADRTGIGEHDVA
MAV_4284|M.avium_104                -------------------MAETPSNPGELARQAAAVIGERTGVAEHDVA
TH_2259|M.thermoresistible__bu      --------------------VTD---PDTAATQAAAAIADRTGVPHHDVA
MSMEG_1701|M.smegmatis_MC2_155      --------------------MTD---PHTSSQAAATAIADRTGVVEHDVA
Mflv_4828|M.gilvum_PYR-GCK          --------------------MDD---PGVLAQQAADELRRRTGVDTHDVA
Mvan_1610|M.vanbaalenii_PYR-1       --------------------MDD---PAALTRRAADALRERTGSDAHDVA
MAB_3660|M.abscessus_ATCC_1997      MTDEAPARGRYPQPARRVDDADDRLAPDDAAALAAAEIATRTGVPAHRVA
                                                              *   :  **  :  ***   * **

MMAR_1219|M.marinum_M               VVLGSGWSAAIAALGSPTAVLAQTEVPGFTPPSAAGHTGELLSVPVG--D
MUL_2673|M.ulcerans_Agy99           VVLGSGWSAAIAALGSPTAVLAQTEVPGFTPPSAAGHAGELLSVPVG--D
MLBr_00707|M.leprae_Br4923          VVLGSGWSSAVAALGSSRAVFPQAELPGFITPNAAGHTGELLSVRIG--A
Mb3335|M.bovis_AF2122/97            VVLGSGWLPAVAALGSPTTVLPQAELPGFVPPTAAGHAGELLSVPIG--A
Rv3307|M.tuberculosis_H37Rv         VVLGSGWLPAVAALGSPTTVLPQAELPGFVPPTAAGHAGELLSVPIG--A
MAV_4284|M.avium_104                IVLGSGWSPAVAALGTPTAVLPQAELPGFRPPTAVGHTGELVSMRIG--E
TH_2259|M.thermoresistible__bu      VVLGSGWAPAVTELGEPVATVPMAELPGFTPPTAAGHRGQLMSTRIG--E
MSMEG_1701|M.smegmatis_MC2_155      VVLGSGWAPAVAELGDPVGVVDMADLPGFTPPTAAGHGGQVLSVRIG--E
Mflv_4828|M.gilvum_PYR-GCK          VVLGSGWAPAATSLGEPDAAIPMADLPGFTPPSAQGHGGQVLSVRAG--P
Mvan_1610|M.vanbaalenii_PYR-1       VVLGSGWAPAAAQIGDPTAAIPMAELPGFTPPSAQGHGGQVLSLRVG--A
MAB_3660|M.abscessus_ATCC_1997      VVLGSGWAPAAGELGTPATTIPMAELPAFSPPSAAGHGGSVLSVPIGGSD
                                    :****** .*   :* .  ..  :::*.* .*.* ** *.::*   *   

MMAR_1219|M.marinum_M               HRVLVLAGRIHAYEGHDLRHVVHPVRTACAAGARTVVLTNAAGGLRPDMQ
MUL_2673|M.ulcerans_Agy99           HRVLVLAGRIHAYEGHDLRHVVHPVRTACAAGARTVVLTNAAGGLRPDMQ
MLBr_00707|M.leprae_Br4923          HRVLVLAGRIHPYEGHDLRHVVHPVRTACAAGARIIVLTNAAGGLRADMA
Mb3335|M.bovis_AF2122/97            HRVLVLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNAAGGLRADLQ
Rv3307|M.tuberculosis_H37Rv         HRVLVLAGRIHAYEGHDLRYVVHPVRAARAAGAQIMVLTNAAGGLRADLQ
MAV_4284|M.avium_104                HRVLVLVGRIHAYEGHDLCHVVHPVRAACAAGVRAVVLTNAAGGLRPDLA
TH_2259|M.thermoresistible__bu      HRALVLIGRIHAYEGHDLSHVVHPVRAACASGVHTVVLTNAAGGLREDFT
MSMEG_1701|M.smegmatis_MC2_155      HRVLVLVGRIHAYEGHDLAHVVHPVRTAVATGVRTVVLTNAAGGLRPEYT
Mflv_4828|M.gilvum_PYR-GCK          HRVLVLLGRIHAYEGHNLRHVVHPVRTACAAGARTVVLTNAAGGVREDMT
Mvan_1610|M.vanbaalenii_PYR-1       HRVLVLLGRIHAYEGHDLRHVVHPVRTACAAGVHTVVLTNAAGGLRADFS
MAB_3660|M.abscessus_ATCC_1997      ERMLILLGRIHAYEGHDLRHVVHPVRTACAAGARTIILTNAAGGLREDYA
                                    .* *:* ****.****:* :******:* *:*.: ::*******:* :  

MMAR_1219|M.marinum_M               VGQPVLISDHLNLTARSPLVGAQFVDLTDAYSARLRAVARQADPELAEGV
MUL_2673|M.ulcerans_Agy99           VGQPVLISDHLNLTARSPLVGAQFVDLTDAYSARLRAVARQADPELAEGV
MLBr_00707|M.leprae_Br4923          VGQLVLISDHLNLTTRSPLVGTHFVDLTNAYTTRLRKLASDTDPTLTEGV
Mb3335|M.bovis_AF2122/97            VGQPVLISDHLNLTARSPLVGGEFVDLTDAYSPRLRELARQSDPQLAEGV
Rv3307|M.tuberculosis_H37Rv         VGQPVLISDHLNLTARSPLVGGEFVDLTDAYSPRLRELARQSDPQLAEGV
MAV_4284|M.avium_104                VGEPVLISDHLNLTGRSPLVGPQFVDLTDAYSPRLRELARQADPTLAEGV
TH_2259|M.thermoresistible__bu      VGQPVLISDHLNLTARSPLVGPQFVDLVDAYSPRLRRIALGIDPSLAEGV
MSMEG_1701|M.smegmatis_MC2_155      VGQPVLISDHLNLTARSPLVGPQFVDLVDAYSPRLRAVAREFDPSLAEGV
Mflv_4828|M.gilvum_PYR-GCK          VGQPVLISDHLNLTARSPLVGAQFVDMVDAYSPALRALARDIDPSLTEGV
Mvan_1610|M.vanbaalenii_PYR-1       VGQPVLISDHLNLTARSPLVGAQFVDLVDAYSPRLRALAREIEPGLAEGV
MAB_3660|M.abscessus_ATCC_1997      VGQPVLISDHLNLTARSPLVGAQFVDLVDAYSPRLRALAREIDDNLTEGV
                                    **: ********** ****** .***:.:**:. ** :*   :  *:***

MMAR_1219|M.marinum_M               YAGLPGPHYETPAEIRMLRVLGADLVGMSTVHETIAARAAGAEVLGVSLV
MUL_2673|M.ulcerans_Agy99           YAGLPGPHYETPAEIRMLRVLGADLVGMSTMHETIAARAAGAEVLGVSLV
MLBr_00707|M.leprae_Br4923          YAAQPGPHYETPAEIRMLRMLGADLVGMSTVHETIAARAAGAEVLGVSLV
Mb3335|M.bovis_AF2122/97            YAGLPGPHYETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLV
Rv3307|M.tuberculosis_H37Rv         YAGLPGPHYETPAEIRMLQTLGADLVGMSTVHETIAARAAGAEVLGVSLV
MAV_4284|M.avium_104                YAGLPGPHYETPAEIRMLRTLGADLVGMSTVHETIATRAAGAEVLGVSLV
TH_2259|M.thermoresistible__bu      YAGLPGPHYETPAEIRMLRTLGADLVGMSTVHETIAARAAGAQVLGLSLV
MSMEG_1701|M.smegmatis_MC2_155      YAGLPGPHYETPAEIRMLRTLGADLVGMSTVHETIAARAAGAEVLAVSLV
Mflv_4828|M.gilvum_PYR-GCK          YAGLPGPHYETPAEIRMLRTLGADLVGMSTVHETIAARACGAAVLGVSLV
Mvan_1610|M.vanbaalenii_PYR-1       YAGLPGPHYETPAEIRMLRTLGADLVGMSTVHETIAARGAGASVLGLSLV
MAB_3660|M.abscessus_ATCC_1997      YAGLPGPHYETPAEIRMLRTLGADLVGMSTVQETIAARAAGAEVLGVSLV
                                    **. **************: **********::****:*..** **.:***

MMAR_1219|M.marinum_M               TNLAAGITGEPLSHAEVLAAGAASAARIGSLLATVIAGLRNSDA
MUL_2673|M.ulcerans_Agy99           TNLAAGITGEPLSHAEVLAAGAASAARIGSLLATVIAGLRNSDA
MLBr_00707|M.leprae_Br4923          TNLAAGITGKPLNHAEVLAAGTASANRIGSLLADIIARF-----
Mb3335|M.bovis_AF2122/97            TNLAAGITGEPLSHAEVLAAGAASATRMGALLADVIARF-----
Rv3307|M.tuberculosis_H37Rv         TNLAAGITGEPLSHAEVLAAGAASATRMGALLADVIARF-----
MAV_4284|M.avium_104                TNLAAGISGEPLSHTEVLAAGAASATRMGALLALILRQLPRF--
TH_2259|M.thermoresistible__bu      TNLAAGMTGEPLSHADVLAAGRESAARMGALLATVIAAM-----
MSMEG_1701|M.smegmatis_MC2_155      TNLAAGMTGEPLSHAEVLQAGRESATRMGALLASVIARL-----
Mflv_4828|M.gilvum_PYR-GCK          TNLAAGMTGQPLSHEEVLAAGRQSATRMGSLLSAVIAGL-----
Mvan_1610|M.vanbaalenii_PYR-1       TNMAAGMTGRPLSHAEVLEAGRQSATRMGSLLSAVIARL-----
MAB_3660|M.abscessus_ATCC_1997      TNLAAGMTGESLNHEEVLAAGRASATRMGQLLRAVIGRL-----
                                    **:***::*..*.* :** **  ** *:* **  ::  :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2259	deoD	-	100% (265)	PROBABLE PURINE NUCLEOSIDE PHOSPHORYLASE DEOD (INOSINE PHOSPHORYLASE) (PNP)
M. thermoresistible (build 8)	TH_0435	pnp	7e-10	28.88% (232)	PROBABLE 5'-METHYLTHIOADENOSINE PHOSPHORYLASE PNP (MTA